12/13/2016 Disclosures Modern Approach To Wound Dressings Fred D Cushner, Cushner, MD • Consultant – Smith and Nephew – Pacira – CHE New York, New York Other Disclosures • My fellows/PA’s Close The Wound – Per My Protocol • I Take The Credit For How Good The Wound Looks – They Get Blame in Any Leakage Wound is Like A Burger Perfect Wound Closure • Watertight Arthrotomy • Skin Edges Approximated – Sub Q – Sub Cutaneous – Skin Level • Dressing 1 12/13/2016 My Closure Evolution • Staples Why Necessary ? • Infection • Infection • Infection – Lots of them • 3.0 Nylon • Prineo Closure System – Mesh – Dermabond – No Staples/Sutures Why Do Knees Fail ? Danger Is Everywhere Risk Factors for PeriProsthetic Infection BMI 50 • Infection • Infection • Infection • • • • • • • • Rheumatoid arthritis Steroid therapy Diabetes mellitus Prior septic arthritis Prior arthroplasty Malignancy Lymphocyte <1.5x109 More than 4 hospital days prior to TJR • Homologous blood transfusion within 24 hrs of prosthetic surgery Duration of hospitalization • Decubitus ulcers • NNIS 1 or greater • Superficial wound infection • Wound drainage • Wound hematoma • Wound dehiscence Berbari EF, et al. Clin Infect Dis.1998;27(5):1247-54. 2 12/13/2016 3 12/13/2016 New Dressings 4 12/13/2016 New Dressings Help Avoid Blisters • Non Non--Circumferential • Tolerate Swelling • Enhanced Healing Environment Dressing Options • • • • Standard 4X4 Ace Wrap Xeroform • Non-Occlusive • Require Frequent Changes • Cost Tourniquet and Blisters • Heller et al – J Arthop 2015 – Blister Incidence • Dressing after Tourniquet Deflation Deflation-- 2.2 % • Dressing Before Deflation – 7.5% Benefits of New Occlusive Dressings 1. Permeable 1.Promotes Healing 2.Avoids Excessive Moisture 2. Hospital Infective Environment – Contamination Avoidance 3. Hypoxic Environment 1.Enhances Healing 2.No Need To Change National Institute for Health and Clinical Excellence. Surgical site infection prevention and treatment of surgical site infection. CG74 Surgical site infection: full guideline. http://guidance.nice.org.uk/CG74/Guidance/pdf/English. October 2008 . Modern Dressings • Langlois Langlois-- International Orthop 2015 – Favored By Patients – Favored B Nurses – Less Frequent Dressing Changes – Similar Wound Appearance OPSITE™ Post Post--Op Visible: visible solutions • Superior absorption5,6 • BacteriaBacteria-proof6 • Waterproof • Provides clear visibility of your surgical wounds. 5 12/13/2016 AQUACEL® Ag SURGICAL Dressing Example of dressing fluid handling Skin-friendly hydrocolloid technology flexes with the skin during body movement Patented Hydrofiber® Technology absorbs and locks in fluid, including harmful bacteria.* 1 Unique construction enhances extensibility and flexibility 2 Polyurethane film provides a waterproof viral and bacterial barrier* (when intact and with no leakage) *As demonstrated in vitro 1Walker M, Hobot JA, Newman GR, Bowler PG. Scanning electron microscopic examination of bacterial immobilization in a carboxymethyl cellulose (Aquacel) and alginate dressings. Biomaterials. 2003;24(5):883-890. 2 Clarke JV, et al. A prospective clinical audit of a new dressing design for lower limb arthroplasty wound. J Wound Care. 2009;18(1):5-8, 10-1. Why Silver ? Aerobic bacteria * Staphlococcus aureus (NCTC 8532) Staphlococcus aureus (clinical isolate) Pseudomonas aeruginoss (clinical isolate, x2 strains) Enterobacter cloacae (clinical isolate) Streptococcus pyogenes (clinincal isolate) Klebsiella pnuemoniae (clinical isolate, x3 strains) Enterococcus faecals (clinical isolate) Escherichia coil (NCIMB 8545) Escherichia coil (NCIMB 10544) Acnetobacter baumannii (NCIMB 9214 Anaerobic bacteria * Bacteroides fragilis (clinical isolate) • Antimicrobial properties of silver well documented in literature • Silver ions bind to the DNA of bacteria and reducing their ability to replicate (Ballard 2002; Cooper 2004). • Controlled release of ionic silver • Prospective randomized study of standard surgical dressing vs AQUACEL® Dressing • 200 pts AQUACEL® dressing 5.8 x more likely to result in a wound with NO complications Peptostreptococcus anaerobius (clinincal isolate) Clostridium ramosum (clinincal isolate) Clostridium clostridioforme (clinincal isolate) Clostridium cadaveris (clinincal isolate) Clostridium perfringens (clinincal isolate) Tissierella praeacute (clinincal isolate) • Only silver exposure when exudate is present • Blister rate 22.5 % in standard group vs 2.4% in AQUACEL® dressing group *As demonstrated in vitro 1. Jones SA, Bowler PG, Walker M, Parsons D. Controlling wound bioburden with a novel silver-containing Hydrofiber® dressing. Wound Repair Regen. 2004;12:288-294. Ann R Coll Surg Engl. 2006;88(1):18-22. 6 12/13/2016 Complex Cases PICO™ PICO ™ • Revision • Obese • Spidey Sense • Incredibly simple, ultra-personal NPWT that can help more patients and reduce the human and economic costs of wounds 42 7 12/13/2016 PICO™ PICO ™ dressing: How does it work? The PICO dressing is constructed from 4 layers: 1. 2. 3. 4. The future of NPWT SEM image of a cross-section of dressing • NPWT is becoming more widely understood and utilized through innovation: A high MVTR upper film Absorbent layer Airlock layer Silicone adhesive layer PICO™ • Simple application and operation • Clinically effective • Cost effective • Powered canister canister--free NPWT Pressure is evenly transmitted by the airlock layer (3), which doesn’t collapse under negative pressure The perforated silicone adhesive layer (4) transmits negative pressure to the wound bed and removes fluid • Enhanced portability • Improve patient experience 43 Summary Wound Rescue Protocol • • • • • Quill Closure Prineo on Skin Simple Dressing for 2 days Smart Dressing For 7 Days on D/C Wound Vac if needed Thank You 8
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