DENNIS S. CHARNEY, M.D. STATE OF THE SCHOOL ADDRESS September 23, 2008 Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Congratulations to Diane E. Meier, M.D. 2008 MacArthur Fellows Program Award Recipient Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Superpower Scientific Dynasties 1735 – 1840 France – Centralized systems led to rigidity and decline of science – Economic decline Mid-18th Century – 1920s Germany – Research oriented university, well equipped labs, and emergence of institutes (Max Planck) – Economic decline Early 20th Century – WWII Britain – Scientific funding from government and vigorous university system – Economic decline WWII – Present United States – World’s economic superpowers – Dominant system of science, NIH Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Superpower Scientific Dynasties • Each former giant of science emerged when the society’s economy became extraordinarily robust by world standards and declined when their economies declined • The message for Mount Sinai is that we must be financially strong Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research 1. Rockefeller University – – – – – – – Founded 1901 First US Institution devoted solely to biomedical research 23 Nobel Prize winners associated with the University 20 Lasker Award winners 13 National Medal of Science winners 35 Members of the National Academy of Sciences 14 Members of the Institute of Medicine Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research Rockefeller University – 69 Laboratories – 6 Research Areas (biochemistry, structural biology, chemistry; immunology, virology and microbiology; molecular, cell and developmental biology; medical sciences and human genetics; neuroscience; physics and mathematical biology) – 9 Interdisciplinary Centers (cancer; hepatitis C; physics and biology; immunology and immune diseases; Alzheimer's disease; sensory neuroscience; biochemistry and structural biology; mind, brain and behavior; human genetics) Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research 2. Salk Institute – Established in 1960 – First lab opened in 1963 with 5 outstanding senior scientists – Currently has 57 faculty investigators organized into 24 laboratories. Has 130 graduate students and 285 postdoctoral trainees. – 3 Centers (Cancer; Theoretical Neurobiology; Theoretical and Computational Biology) – 3 Current faculty are Nobel Laureates, 5 scientists trained at Salk have Nobel Prize Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research Salk Institute – Major areas of focus within 3 areas: molecular biology and genetics; neurosciences ; and plant biology – New directions include chemistry and proteomics; stem cell biology; cell and regulatory biology; metabolic research and computational and theoretical biology – Many major discoveries relevant to human health and diseases Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research 3. Scripps Research Institute – Founded in 1961 by a small group of immunopathologists – 225 Faculty, 235 graduate students, and 815 postdoctoral fellows – 3 Nobel Laureates, 19 NAS members, 8 IOM members – Organized into 7 primary departments (cell biology; chemistry; immunology; molecular biology; experimental medicine; neurobiology; and neuropharmacology) – 8 Centers and Institutes, and 5 consortium – “Rather than insulating faculty members and laboratories into separate and distinct disciplines, as is generally the prescribed university model, the cooperative, collaborative spirit is encouraged and embraced. While the level of scientific investigation is intense, the atmosphere is collegial. The pursuit of scientific excellence is paramount and all efforts are directed toward that end.” Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Research Scripps Research Institute – The Kellog School of Science and Technology, founded about a decade ago, is one of the nation’s best. Coursework is designed to focus on the interplay of disparate fields of study and the student experience transcends multiple laboratories. – Scripps plans to start a small medical school (32-40 students per class) in which every graduate will receive both a medical degree (MD) and a scientific degree (MS or PhD) Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Principles of Success 1. Very high quality of senior leadership 2. Organizational Flexibility – goes where science leads, integration rather than segregation 3. Very high caliber faculty who value scientific diversity and collaboration 4. Expectation of Excellence 5. Outstanding Mentorship Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Sports Dynasties OWNER COACH PLAYERS BOSTON CELTICS 1957-1969 11 Championships Brown Auerbach Russell NEW YORK YANKEES 1947-1962 10 Championships Webb Topping Stengel DiMaggio Mantle UCLA COLLEGE BASKETBALL 1996 -1973 7 Championships UCLA Wooden Abdul-Jabbar Walton GREEN BAY PACKERS 1961-1968 4 Championships Green Bay Fans Lombardi Starr Nickske UNC WOMEN’S SOCCER 19 National Championships in 30 years UNC Dorrance Olympics 1996 – 6(2) 2000 – 6 (2) 2004 – 6 (2) 2008 - 5 Accelerating Science Advancing Medicine Achieving and Maintaining Greatness The Ingredients needed for Achieving and Maintaining Greatness 1. Great Administrative Leadership (Dean, CEO) 2. Great Leaders of People (Chairs, Institute Directors) 3. Great Players (Scientists, Physicians) All 3 are NEEDED. Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Academic Medical Centers and Problems in Making Major Discoveries 1. Increased differentiation (silos) and less integration and collaboration 2. More Bureaucracy 3. When research organizations respond to growth by differentiating into new departments and by imposing hierarchical and bureaucratic controls → limiting the process of crossing academic disciplines and a decline in integration and diminished possibility of major discoveries 4. Most medical schools lack flexibility and there is a sharp differentiation between clinical sciences and basic sciences 5. Has resulted in relatively few major discoveries in the 20th century Accelerating Science Advancing Medicine Achieving and Maintaining Greatness The Challenge to Mount Sinai Leadership – Provide a strategic vision for integrating diverse areas of science to facilitate breakthrough research on important biomedical research questions – Recruit outstanding faculty across diverse areas of biomedical science so that our research teams remain at the cutting edge of science – Demand rigorous evaluation of science within a nurturing environment – Place a high value on outstanding training and mentorship – Facilitate the obtaining of funding necessary for great science – Expectation of excellence and nothing less Accelerating Science Advancing Medicine Achieving and Maintaining Greatness The Challenge to Mount Sinai Scientists – Work on Important Problems which are “Do-able” leading to breakthroughs – Develop Research Teams characterized by Diversity and Depth – Reach across disciplines – Encourage frequent and intense interactions with those having complementary interests – Value mentorship – Peer evaluation and support Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Strategies for Facilitating Biomedical Breakthroughs Academic Medical Centers Mount Sinai 1. Take advantage of the access to patient populations 2. Take advantage of clinical departmental structure that provides a platform for translational and clinical research and training 3. Create multidisciplinary interdepartmental research institutes and centers which are high in scientific diversity, depth, and integration. Encourage a highly focused research effort and intense and frequent interaction of faculty from diverse backgrounds 4. Create a Departmental-Institute matrix that results in scientific breakthroughs relevant to human disease Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Clinical Care Mayo Clinic – The first and largest integrated not for profit medical group practice in the world – “Mayo Clinic is a collaborative organization, a pliable institution that assembles the expertise needed for individual patients. Once the teams provide the necessary care, they disband and reconfigure to meet the medical needs of other patients. Imagine a huge store that sells everything, with experts in every department who work together to help customers. This is how Mayo Clinic is designed for medical customers. Patients don't get just a doctor; they get, in effect, the ‘whole company.’ The Mayo system of integrated, multi-specialty, outpatient and inpatient medical care doesn't always work as intended. But it does work most of the time and represents Mayo Clinic's most important competitive advantage.” Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Clinical Care Mayo Clinic Model of Care • Principles of Outstanding Patient care − Collegial, cooperative, staff teamwork with multispecialty integration. A team of specialists is available and appropriately used. − Highest quality patient care provided with compassion and trust. − Comprehensive evaluation with timely, efficient assessment and treatment. − Availability of the most advanced, innovative diagnostic and therapeutic technology and techniques. Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Biomedical Dynasties Clinical Care • Mayo Clinic's brand is world-class because it reassures; it evokes confidence in customers who truly need to trust. In the end, great services brands are built on excellent customer experiences, and this is the meta branding lesson the Mayo Clinic teaches. • Our goal is to establish Mount Sinai as a world class brand of outstanding patient centered clinical care • When the patient comes to Mount Sinai, they get the entire institution Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Research Productivity 2007-2008 • MSSM is now #18 in NIH Funding with ~$193M in grants (does not include some recent recruits) – This represents approx. 3% over 2007 grants of $187.5M • The efficiency of space utilization has improved – In 2006, the average institutional research density was $565/sf – In 2007, the average institutional research density was $639/sf – In 2008, the average institutional research density is $651/sf • This increase has enabled us to make major recruitments within our existing space Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Research Productivity 2007-2008 Enhancement of Research Support: – Clinical Trials Office Centralized clinical trials office will provide support to researchers during all phases of a trial – Info Ed A specialized application to assist in electronic NIH submission and tracking of grants – Data Warehouse Patient data available to clinicians electronically, improving efficiency – Vivarium Renovations completed for specialized cardiac and behavioral research – Shared Research facilities Creation of new RNAi core, Biorepository Cooperative and enhancements to existing ones, e.g. Microscopy Renovations to house new Cell Sorter to commence shortly Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Research Goals 2009 • Continue to increase NIH Funding at least 5% annually • Increase number of NIH Centers of Excellence • Increase Training Grant awards • Recruit and retain our top scientists • Conduct breakthrough science Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Growth of the Office of Technology and Business Development • Internal Marketing Program – Internship Program – Technology Scouts, Reviewers – More Faculty Education on OTBD Process and What Attracts Industry – Improved Integration with Departments (Attend Departmental Meetings etc.) • External Marketing Program – Develop New Industry Relationships – Broad Based Marketing of MSSM Research and Technologies to Companies • Technology Development Fund – Fund Product Development Projects – Improve Value of Early Stage Technologies Accelerating Science Advancing Medicine • Expand Entrepreneurial Activities – Industry Presentations – VC Introductions – Commercialization Workshops • Develop Relationships with Drug Discovery and Device Prototype Companies • Process Improvement – Use of External Resources to Facilitate Evaluations – Reduce Turn Around Times – Improved Website / Electronic Disclosure Filing Achieving and Maintaining Greatness Medical Education Accomplishments 2007-2008 Recognition – AAMC Spencer Foreman Community Service award: one of three national finalists – AMSA PharmFree Report Card: ranked #3 in the country for the integrity of our COI policies for faculty and students Recruitment – Second class of 140 – GPA 3.66, MCAT 34.8 – Intense focus on diversity, community service and leadership in social advocacy – Over half the class from the following schools Columbia, Yale, NYU, Princeton, Penn, Brown, Cornell, Duke, Harvard, Northwestern Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Medical Education Accomplishments 2007-2008 Curriculum – Accelerating Science: implemented INSPIRE, providing yet another opportunity for students to incorporate mentored scholarship into their medical education – Advancing Medicine: one of two schools in the country to implement a Longitudinal Clinical Experience for an entire entering class, allowing students to experience doctoring from the very start, and helping them ‘translate’ the science they learn into a clinical context Space – Completed Phase Three of our renovation: Annenberg 13 labs and classrooms Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Medical Education Goals 2009 Recognition – NIH rank will break into top 15 – USNWR will break into top 20 – We will win the AAMC Spencer Foreman Community Service award – Continue to fill major national roles in medical education (ex. Associate Dean Suzanne Rose will Chair the AAMC Group on Educational Affairs) Recruitment – Third class of 140 – GPA will surpass 3.70, MCAT will surpass 35.0 – Continue to focus on recruiting diverse student leaders in research, community service, education, and clinical care Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Medical Education Goals 2009 Curriculum – Accelerating Science: implement the MD/MSCR track as a viable alternative to training translational researchers – Advancing Medicine Expand the Longitudinal Experience into the second year Complete curricular mapping based on Competencies, allowing us to redistribute basic principles of clinical care into the first two years, and more sophisticated science into the third and fourth years Space – Complete the 4th and final phase of renovation: Lecture Room 12-01 Simulation – Unveil The Center for Quality, Education, and Patient Safety through Simulation, a joint venture of the Departments of Medical Education and Anesthesiology, co-directed by Yasuharu Okuda and Adam Levine Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Graduate School of Biological Sciences Accomplishments 2007-2008 Fewer acceptances with higher standards • MD/PhD: 14 Students – Mean GPA, 3.7 – Mean MCATs, 34 – Representative Undergrad institutions: Columbia, NYU, Princeton Cornell, U. Washington, Johns Hopkins, U. Penn, UC Berkeley • PhD: 31 Students – Mean GPA: 3.52 – Median GREs: Analytical Writing, 5 (out of 6); Quant., 740; Verbal, 590 – Representative Undergrad institutions: Yale, Caltech, Emory, Cornell, Peking Univ., NYU, U. Rochester, Melbourne U., Vassar, Franklin & Marshall Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Graduate School of Biological Sciences Goals 2009 • Four new Training areas matching the newly formed Research Institutes established: – Cancer Biology, Development & Stem Cell Biology, Immunology and Pharmacology & Systems Biology • Growth of Graduate School will track that of the Institutes • Emphasis on depth over breadth – All training areas must be outstanding • Leverage close linkage with Med School & Hospital Develop high-quality programs Training in an integrated environment promoting Translational research • Establish new metric that measures performance based on impact of publications that emerge from thesis work • Mount aggressive marketing & public relations campaigns to publicize these efforts Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Faculty Practice Associates Accomplishments 2007-2008 • The practice has seen exceptional growth • Jan-Jun 2007 vs 2008 – Membership in FPA has grown by 4% – Number of visits grew by 9% – wRVUs grew by 9% – Receipts grew by >19% • Successful recruitment of outstanding clinicians has driven the volume and receipts • Emphasis on core values has resulted in better patient satisfaction (But we can do better) Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Faculty Practice Associates Accomplishments 2007-2008 FPA Patient Ins titution Care Receipts Northwes tern U F einberg S OM compared to C ornell U Weill Med C oll Was hington Univers ity S OM other Top E mory Univers ity S ch of Med Ranked Univers ity of Wis cons in Schools Mount S inai S O M C olumbia U C oll of P & S Yale Univers ity S OM Mas s achus etts G eneral Hos pital D uke Univers ity S ch of Med Univers ity of Michigan Med S ch Univers ity of P enns ylvania S OM UC L os A ngeles G effen S OM J ohns Hopkins Univers ity S OM B eth Is rael-D eacones s Med C tr UC S an F rancis co S ch of Med Oregon Health & S cience U U North C arolina S OM Univers ity of Was hington S OM UC S an D iego S ch of Med Univ C olorado Hlth S ci C tr S OM Accelerating Science Advancing Medicine T otal R ec eipts $361,567,541 359,386,966 487673805 419,174,882 432,802,603 # of F ac ulty 600 706 1,045 937 1,068 R ec eipts /MD 2007 $602,613 509,047 466,673 447,358 405,246 309,488,186 786 393,751 408,496,245 250,779,688 412,947,087 343,179,103 353,011,655 332,891,000 309,589,739 332,774,595 190,833,000 232,244,046 162,611,333 162,522,871 136,721,523 173,329,149 172,892,993 1,200 762 1,300 1,131 1,294 1,259 1,200 1,431 830 1,049 806 901 947 1,228 1,613 340,414 329,107 317,652 303,430 272,807 264,409 257,991 232,547 229,919 221,396 201,751 180,381 144,441 141,126 107,187 Achieving and Maintaining Greatness Faculty Practice Associates Goals 2009 • Improve Governance: – Enhance collaboration amongst departments • Improve Revenue Cycle Performance – Improve internal business processes & strengthen in-house expertise – Unify revenue cycle operations of all interested departments • Improve Patient Experience – Continually demonstrate improved patient satisfaction scores – Compare performance improvement to peers • Grow Clinical Programs – – – – Maintain annual growth in revenue of at least 12% Targeted recruitments aligned with institutional priorities & goals Establishment of new categories of membership to enable growth Recruit outstanding clinicians Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Campus Renovations-2007 • IMI-2 - Cancer Epidemiology • Atran 5 - Cardiovascular Research Center • Annenberg 5 - Graduate School Classroom • Annenberg 5 - Medical Education Administrative Offices • Annenberg 12 - Medical School Classrooms • Annenberg 15 - Pathology Lab & Offices – Phase 1 • Annenberg 18 - Medicine Labs, RNAi & Microscopy SRF upgrade • Annenberg 19 - Pharmacology Labs – Phase 1 & 2 • Annenberg 21 - Administrative Offices • Annenberg 25 - Stem Cell Research Labs for new recruit • Annenberg 26 - Vivarium Renovations for CRC $ 74M Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Campus Renovations-2008 • • • • • • • • • • • • • • • • Center for Advanced Medicine completed IMI-1 - Cancer Institute Administrative & Academic Offices IMI-16 - Structural Biology IMI-10 - BSL 2 Cell Sorter Atran 6 - Cardiovascular Research Lab Atran 7 - Stem Cell Institute Lab Atran 8 - Cardiac Imaging & Computational Lab Annenberg 13 - Medical School Classrooms Annenberg 15 - Pathology Lab & Offices – Phase 2 Annenberg 19 - Pharmacology Labs – Phase 3 Annenberg 22 - Ophthalmology Clinician Offices Annenberg 24 - Cancer Institute Labs – Phase 1 & 2 Annenberg 25 - Molecular Biology Labs Annenberg 26 - Vivarium Renovations for Behavior Annenberg-SC - MRI upgrade 3 East 101st - Conversion of guest house floors to offices • FPA: – – – – – – Accelerating Science Advancing Medicine Jaffe Allergy Institute Bendhein Parkinson Center Surgery Floor Renovations Ruttenberg Cancer Center Urology Clinical & Robotics Breast Center $97M Achieving and Maintaining Greatness Campus Renovations-Plans for 2009 • GP 1 - Mount Sinai Heart Exam Rooms & Offices • GP 2 - Mount Sinai Heart Education Center • IMI 4 - Health Policy – renovations for Dr. Rose • Annenberg 11 - Levy Library upgrade • Annenberg 12 - Medical School Auditorium • Annenberg 14 - Brain Institute Labs • Annenberg 19 - Pharmacology (Brain & Cancer Institute) Labs • Annenberg 20 - Neurology Labs • Annenberg 22 - Psychiatry (Brain Institute) Labs • Annenberg 23 - Medicine Labs – Phase 1 • Annenberg 24 - Cancer Institute Labs – Phase 3 • FPA at 5 East 98th: - Orthopedics Space Renovation $26M Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Campus Renovations-2007-2009 Annenberg 26 25 24 23 22 21 20 19 Icahn Medical Institute 18 17 16 16 15 15 14 14 13 13 12 Atran Laboratory/Berg Institute 11 10 5 East 98th Street (FPA) Guggenheim Pavillion 8 8 Center for Advanced Medicine 11 10 8 14 12 12 11 11 10 10 9 9 8 8 8 7 7 9 9 15 7 7 7 7 6 6 6 6 6 6 5 5 5 5 5 5 4 4 4 4 4 4 3 3 3 3 3 3 2 2 2 2 2 2 1 1 1 1 1 1 2007 2008 2009 3 101st Street 5 4 3 2 1 3-year Capital Spending $197M (does not include CSM – related expenses) Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Center for Advanced Medicine • Conversion of garage to office & clinical use for both hospital & school functions in 160,000NSF: – Department of Community Medicine offices & programs – Disease Prevention & Public Health Institute – Clinical Trials groups in Cancer & Ophthalmology – Bronfman Institute for Personalized Medicine Biomedical Informatics Center – Clinical Translational Research Institute – Graduate School programs in MPH & MS – Ophthalmology Faculty Practice • Hospital clinics are housed with clinical trials and bio-bank personnel • Co-location of research and clinical functions provides patients easy access to novel treatments Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Center for Advanced Medicine Exterior View – from Fifth Avenue & 101st Street Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Center for Advanced Medicine Interior view of 6-storey atrium and picture wall Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Center for Science & Medicine • 500,000 GSF of research and clinical space • Construction Start 2008 • Expected Completion – 2011 Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Center for Science & Medicine View from Southeast Accelerating Science Advancing Medicine East Elevation Achieving and Maintaining Greatness Center for Science & Medicine Lobby Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Faculty Recruits 2007-2008 Assistant Professors 119 Assistant Professors Pending 53 Associate Professors 28 Professors 22 Department Chairs 2 Total Recruits 224 Accelerating Science Advancing Medicine Achieving and Maintaining Greatness 2008 Financial Results: • Operating Surplus 8 Months Ending August - $4.0 Million – – – – Research Growth 12.1% FPA Growth 17.0% Royalty/Licensing income to exceed $30 million for year Total operating revenues 13% growth for year to $1.1 Billion • Capital Budget $101 Million – 2005 – 2008 Capital Budget for existing facilities – Totals $317 Million • Favorable Bond Ratings Mean Lower Borrowing Costs – S&P A– Positive Outlook – Moody’s A3 Positive Outlook Accelerating Science Advancing Medicine Achieving and Maintaining Greatness 2009 Financial Goals: • Minimum Breakeven Operating Results • Maintain Research & FPA Growth Rates • Manage Program and Administrative Services Expenses (VERY IMPORTANT) • Continue Strategic Plan for Growth – Research & Clinical Faculty Recruitment – CSM Borrowing and Building – Capital Campaign Fund Raising Accelerating Science Advancing Medicine Achieving and Maintaining Greatness The Campaign For Mount Sinai Goals Campaign Objective $1B 1000 900 Dec. 2012 Campaign Totals CY2008 800 Millions 700 600 Current Goal Nucleus Phase 500 August 2008 $353.4M* 400 300 200 100 Dec. 2008 $400M-$450M Dec. 2007 $300M CY 2008 8/31/08 $106.7M Dec. 2009 $500M $150M 0 *Includes $75M reach-back gift from 1999 Accelerating Science Advancing Medicine Achieving and Maintaining Greatness The Campaign For Mount Sinai Update Donor Gift Amount Area Supported Frederick Klingenstein $75,000,000 Campaign James Tisch $40,000,000 The Cancer Institute Charles Bronfman $12,000,000 Personalized Medicine Leon Black $10,000,000 The Stem Cell Institute The Nash Family $10,000,000 The Brain Institute Accelerating Science Advancing Medicine Achieving and Maintaining Greatness Keys to Our Success • Great leadership at all levels • Financial discipline • Transparent decision-making based on performance • Recruitment and retention at all levels • Alignment of Education, Research & Clinical mission A CULTURE OF EXCELLENCE Accelerating Science Advancing Medicine Achieving and Maintaining Greatness
© Copyright 2026 Paperzz