Protein
PB2
Highly conserved sequencesa
10-LMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNP-43 (17)
LMSQSRTRE
MSQSRTREI
SQSRTREIL
SRTREILTK
REILTKTTV
ILTKTTVDH
LTKTTVDHM
KTTVDHMAI
TTVDHMAII
TVDHMAIIK
VDHMAIIKK
DHMAIIKKY
HMAIIKKYT
MAIIKKYTS
IIKKYTSGR
IKKYTSGRQ
KYTSGRQEK
45-LRMKWMMAMKYPITADKRI-63 (9)
LRMKWMMAM
RMKWMMAMK
MKWMMAMKY
WMMAMKYPI
MMAMKYPIT
MAMKYPITA
MKYPITADK
KYPITADKR
YPITADKRI
68-PERNEQGQTLWSK-80 (2)
ERNEQGQTL
RNEQGQTLW
92-SPLAVTWWNRNGP-104 (1)
LAVTWWNRN
121-KVERLKHGTFGPVHFRNQVKIRRRVD-146 (11)
VERLKHGTF
LKHGTFGPV
HGTFGPVHF
GTFGPVHFR
GPVHFRNQV
PVHFRNQVK
VHFRNQVKI
HFRNQVKIR
FRNQVKIRR
RNQVKIRRR
QVKIRRRVD
228-YIEVLHLTQGTCWEQMYTPGGEV-250 (8)
YIEVLHLTQ
VLHLTQGTC
LHLTQGTCW
LTQGTCWEQ
QGTCWEQMY
GTCWEQMYT
WEQMYTPGG
QMYTPGGEV
252-NDDVDQSLIIAARNIVRRA-270 (7)
DVDQSLIIA
VDQSLIAA
SLIIAARNI
LIIAARNIV
IIAARNIVR
IAARNIVRR
AARNIVRRA
278-ASLLEMCHSTQIGG-291 (3)
SLLEMCHST
LEMCHSTQI
MCHSTQIGG
345-LTGNLQTLK-353 (1)
LTGNLQTLK
356-VHEGYEEFTMVG-367 (2)
HEGYEEFTM
EGYEEFTMV
369-RATAILRKATRR-380 (2)
Class Ib
Class IIc

B8
B39, B44, B62
A3, B27
A2, B44
A2
A26
B58
A2, A26
A1, A3
A3
A1, A26
A2

A3

A3
DR




DR
DR






DR
DR
DR

B8, B27, B39
A3, B8, B27
A1, A3, B27, B62
A2, A24, B7, B8, B27, B62
A2
A2, A3
A3, B27
A24
B7
DR

DR
DR
DR
DR



B27, B39
B58



DR
A24, B8, B44, B62

B58
A1, A3
B7
A3
A2, B39
A3
A3, B27
A3
B8
DR
DR




DR

DR


A1

B58

A1
B62

A1, A2, B62

DR




DR

A2
B44
A2
A2
A3
A2, A3
B7



DR
DR
DR

A2
A24, B44


DR
DR
A1, A3

B44
A2, A26


PB1
TAILRKATR
AILRKATRR
400-VAMVFSQEDCM-410 (1)
VAMVFSQED
412-KAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLF-446 (21)
KAVRGDLNF
AVRGDLNFV
VRGDLNFVN
LNFVNRANQ
NFVNRANQR
FVNRANQRL
VNRANQRLN
NRANQRLNP
RANQRLNPM
QRLNPMHQL
RLNPMHQLL
LNPMHQLLR
PMHQLLRHF
MHQLLRHFQ
HQLLRHFQK
QLLRHFQKD
LLRHFQKDA
LRHFQKDAK
RHFQKDAKV
HFQKDAKVL
FQKDAKVLF
479-RVSKMGVDEYS-489 (1)
VSKMGVDEY
509-GNVLLSPEEVSETQG-523 (1)
NVLLSPEEV
527-LTITYSSSMMWEINGPESVL-546 (6)
LTITYSSSM
TITYSSSMM
ITYSSSMMW
YSSSMMWEI
MMWEINGPE
WEINGPESV
548-NTYQWIIRNWE-558 (2)
NTYQWIIRN
TYQWIIRNW
570-MLYNKMEFEPFQSLVPKA-587 (5)
MLYNKMEFE
YNKMEFEPF
MEFEPFQSL
FEPFQSLVP
EPFQSLVPK
614-QIIKLLPFAAAPP-626 (4)
QIIKLLPFA
IIKLLPFAA
IKLLPFAAA
LLPFAAAPP
628-QSRMQFSSLTVNVRGSGMRIL-648 (11)
QSRMQFSSL
SRMQFSSLT
RMQFSSLTV
MQFSSLTVN
QFSSLTVNV
FSSLTVNVR
LTVNVRGSG
TVNVRGSGM
VNVRGSGMR
NVRGSGMRI
VRGSGMRIL
685-GVESAVLRGFLI-696 (3)
VESAVLRGF
ESAVLRGFL
SAVLRGFLI
1-MDVNPTLLFLKVP-13 (4)
MDVNPTLLF
DVNPTLLFL
VNPTLLFLK
NPTLLFLKV
15-QNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSE-51 (13)
NAISTTFPY
A3
A3



DR
B58, B62
A2, A26


A3
A1, A2, B7, B8, B39, B62

B27
A2, B7, B8, B58, B62
B27, B39
A1, A2, A3, A24, B8, B58, B62
A2
A24, B62

A3, B27
A2
A2
B27
A2, B27
A2, B8, B39
A1, A24, B8, B27, B39, B44, B62


DR
DR

DR
DR




DR

DR



DR


DR
A1, A26, B62

A2

A1, A2, A26, B7, B58, B62
A26, B7
A1, A3, A24, B58, B62
A1, A2, A24, B58
B62
B44
DR

DR
DR

DR
A2, A3
A24



B8, B62
A2, B39, B44, B62
B44
A3
DR
DR

DR

A2, A26
B8



DR
DR
DR
A2, B7, B8
B27
A1, A2, A3, A24, B7, B8, B27, B62

A2


A26, B7, B62

B7
B27, B39



DR

DR
DR

DR

DR
B44, B62
A26
A24, B7



A1, B44, B62
A2, A26
A3
B7, B8
DR



A1, A3, A26, B8, B58, B62

AISTTFPYT
ISTTFPYTG
FPYTGDPPY
YTGDPPYSH
YSHGTGTGY
HGTGTGYTM
GTGYTMDTV
GYTMDTVNR
YTMDTVNRT
TMDTVNRTH
DTVNRTHQY
VNRTHQYSE
114-VQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIE-148 (14)
VQQTRVDKL
RVDKLTQGR
KLTQGRQTY
LTQGRQTYD
TQGRQTYDW
GRQTYDWTL
QTYDWTLNR
WTLNRNQPA
TLNRNQPAA
LNRNQPAAT
NRNQPAATA
RNQPAATAL
NQPAATALA
AATALANTI
196-TKKMVTQRTIGKKK-209 (4)
KKMVTQRTI
MVTQRTIGK
VTQRTIGKK
TQRTIGKKK
337-LSIAPIMFSNKMARLGKGYMFESK-360 (12)
LSIAPIMFS
SIAPIMFSN
IAPIMFSNK
APIMFSNKM
IMFSNKMAR
MFSNKMARL
FSNKMARLG
SNKMARLGK
KMARLGKGY
MARLGKGYM
ARLGKGYMF
RLGKGYMFE
362-MKLRTQIPAEMLA-374 (4)
MKLRTQIPA
KLRTQIPAE
LRTQIPAEM
RTQIPAEML
474-GINMSKKKSYIN-485 (3)
INMSKKKSY
NMSKKKSYI
MSKKKSYIN
487-TGTFEFTSFFYRYGFVANFSMELPSFGVSG-516 (17)
TGTFEFTSF
GTFEFTSFF
TFEFTSFFY
FEFTSFFYR
EFTSFFYRY
FTSFFYRYG
TSFFYRYGF
SFFYRYGFV
FFYRYGFVA
FYRYGFVAN
YRYGFVANF
RYGFVANFS
YGFVANFSM
FVANFSMEL
ANFSMELPS
NFSMELPSF
SMELPSFGV
518-NESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYR…
NESADMSIG
A2

A1, A26, B7, B8, B62

A1, A3, A26, B27, B58, B62
B39
A1
A3
A1, A2, A26
A1
A1, A26, B62


DR

DR
DR



DR


DR
A24, B62
A3
A1, A2, A3, B8, B58, B62

B58
B27, B39, B44
A1, A2, A3

A2

B27
B7, B8, B39, B44, B62
A2
A2
DR


DR



DR

DR




A24, B27
A3
A3
A3

DR



A2, A3
A3, A26
B7
A3
A24, B8

A3
A1, A3, A26, B8, B27, B58, B62
B7, B8
A1, A24, B8, B27, B39
A3
DR



DR
DR
DR


DR



A2
B27
A1, B58, B62
DR

DR

B62
A2, B8

DR

DR
B58
A1, A26, B58, B62
A1, A3, A24, A26, B62
A3, A2, B44
A1, A24, A26, B8

A26, B58, B62
A24
A2, B8, B39

A1, A26, B8, B27, B39, B62
A24
B8, B39, B58, B62
A1, A2, A3, A26, B7, B8, B39, B58, B62
A3
A24
A1, A2



DR

DR


DR
DR
DR

DR
DR



B44

PA
ESADMSIGV
ADMSIGVTV
DMSIGVTVI
MSIGVTVIK
VTVIKNNMI
TVIKNNMIN
IKNNMINND
MINNDLGPA
INNDLGPAT
NNDLGPATA
LGPATAQMA
GPATAQMAL
ATAQMALQL
TAQMALQLF
AQMALQLFI
QMALQLFIK
ALQLFIKDY
LQLFIKDYR
…QLFIKDYRYTYRCHRGDTQIQTRRSFE-575 (28)
QLFIKDYRY
LFIKDYRYT
FIKDYRYTY
IKDYRYTYR
YRYTYRCHR
YTYRCHRGD
YRCHRGDTQ
GDTQIQTRR
TQIQTRRSF
656-MEYDAVATTHSW-666 (2)
MEYDAVATT
DAVATTHSW
668-PKRNRSILNTSQRGILEDEQMYQ-690 (8)
KRNRSILNT
NRSILNTSQ
RSILNTSQR
ILNTSQRGI
LNTSQRGIL
RGILEDEQM
GILEDEQMY
ILEDEQMYQ
29-KIETNKFAAICTHLEVCFMYSDFHFI-54 (12)
KIETNKFAA
IETNKFAAI
KFAAICTHL
FAAICTHLE
AAICTHLEV
CTHLEVCFM
THLEVCFMY
LEVCFMYSD
EVCFMYSDF
VCFMYSDFH
CFMYSDFHF
FMYSDFHFI
130-YYLEKANKIKSE-141 (3)
YYLEKANKI
YLEKANKIK
LEKANKIKS
143-THIHIFSFTGEEMA-156 (2)
HIFSFTGEE
IFSFTGEEM
185-RGLWDSFRQSERGEETIEE-203 (5)
GLWDSFRQS
FRQSERGEE
RQSERGEET
QSERGEETI
SERGEETIE
298-HEGEGIPLYDAIKC-311 (2)
HEGEGIPLY
IPLYDAIKC
560-SRPMFLYVRTNGTSK-574 (6)
SRPMFLYVR
RPMFLYVRT
MFLYVRTNG
FLYVRTNGT
A1, A2, A26
A2, B44
A2
A3
A1, A2, A24
A3

A3

A2

B7, B8, B39
A1,A2, A3, B7, B39, B58
A24, B58, B62
A2, A24, B44, B62
A2, A3
A1, A2, A3, A26, B62


A1, A3, A26, B8, B58, B62

A1, A3, A26, B8, B27, B62

A1, A3, B27


A3
A24, B7, B27, B39, B62




DR

DR
DR
DR

DR






DR
A2, B44
B58
DR

B27
B27
A3
A2

B58
A1, A26, B62
A2



DR
DR


DR
A2
B8, B44
A2, A24, B44, B58

A2, A26
A2, A26
A1, B39

A26
A3
A24, B58
A2, A24, B8, B39, B62



DR



DR

DR

DR
A2, A24, B39
A1, A2, A3, A24

DR

DR
A3


DR
A2

B62
A1
B44





A1, A26, B44, B62
B7

DR
B27
B7

A2, B8


DR
DR

DR
DR
DR
DR
DR
DR


NP
M1
LYVRTNGTS
YVRTNGTSK
1-MASQGTKRSYEQMET-15 (3)
MASQGTKRS
ASQGTKRSY
GTKRSYEQM
35-GIGRFYIQMCTELKL-49 (5)
IGRFYIQMC
GRFYIQMCT
FYIQMCTEL
YIQMCTELK
IQMCTELKL
66-MVLSAFDERRN-76 (2)
MVLSAFDER
VLSAFDERR
78-YLEEHPSAGKDPKKTGGPIY-97 (4)
LEEHPSAGK
HPSAGKDPK
PSAGKDPKK
DPKKTGGPI
110-LYDKEEIRRIWRQANNG-126 (4)
KEEIRRIWR
IRRIWRQAN
RRIWRQANN
RIWRQANNG
241-DQVRESRNPGNAEIEDL-257 (2)
QVRESRNPG
SRNPGNAEI
410-QPTFSVQRNLPF-421 (1)
FSVQRNLPF
1-MSLLTEVETYVLSI-14 (4)
SLLTEVETY
LLTEVETYV
LTEVETYVL
EVETYVLSI
122-GALASCMGLIYNRMG-136 (4)
GALASCMGL
ALASCMGLI
LASCMGLIY
SCMGLIYNR
175-HENRMVLASTTAKAMEQMAGSSEQAAEAME-204 (9)
NRMVLASTT
RMVLASTTA
MVLASTTAK
VLASTTAKA
LASTTAKAM
TTAKAMEQM
EQMAGSSEQ
QMAGSSEQA
SSEQAAEAM
208-QARQMVQAMR-217 (2)
QARQMVQAM
ARQMVQAMR

A3, B7
DR
DR
A1
A1, A26, B62
A26, B8




B27
A2, A24, B39, B44
A3
A2, A24, B27, B39, B44, B62
DR

DR
DR
DR
A3, A26
A3


A3
B7
A3
B7, B8




A3

B27
A2

DR


A3
B27, B39


A1, A26, B7, B8, B39, B58, B62
DR
A1, A2, A3, A26, B58, B62
A2
A1, B8, B39
A1, A2, A26




A2
A2, A3
A1, A3, A26, B58. B62
A3


DR

B27
A2, B62
A3
A2, A3
B7, B8, B62
A1, A26, B58
B62
A2, B62
A1


DR
DR
DR







B7, B8, B62
A3, B27