Experts' Seminar on Ageing and Long-Term Care Needs LSE, Friday, 20 May 2011 The longevity revolution Jean-Marie Robine INSERM, Paris & Montpellier, France How many newborn are becoming adults? sex women 100000 Somme de lx 100000 90000 100000 80000 98000 70000 95000 country Denmark England France Japan Netherlands Norway Sweden Switzerland USA 60000 96000 90000 50000 40000 94000 85000 30000 92000 80000 20000 10000 75000 90000 0 2010 2000 1990 19801985 1970 1980 1960 1975 1950 1970 1940 1965 1930 1920 1950 1955 1960 1990 1995 1751 1776 1801 1826 1851 1876 1901 1926 1951 2000 1976 20052001 Year How far will the adult longevity go up? Halley, first life table, 1693 10000 9000 Halley 1687-1691 8000 7000 6000 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Sweden, 1754-1756, data sent by Wargentin to Deparcieux 10000 9000 Halley 1687-1691 8000 Sweden 1754-1756 7000 6000 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Switzerland, 1876-1880 10000 9000 Halley 1687-1691 Sweden 1754-1756 8000 Switzerland 1876-1880 7000 6000 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Japan, 1950-1954 10000 9000 Halley 1687-1691 Sweden 1754-1756 8000 Switzerland 1876-1880 7000 Japan 1950-1954 6000 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Japan, 1950-1954 10000 9000 Halley 1687-1691 Sweden 1754-1756 8000 Switzerland 1876-1880 7000 Japan 1950-1954 6000 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Japan 1980-1984 10000 9000 Halley 1687-1691 8000 Sweden 1754-1756 Switzerland 1876-1880 7000 Japan 1950-1954 6000 Japan 1980-1984 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 How long are adult life durations? 6 000 5 000 Modal length of life (M) 4 000 1876-80 1929-32 3 000 1988-93 2 000 Standard deviation above M 1 000 Maximum life span 0 20 40 60 80 100 Distribution of the ages at death in Switzerland 1876-1880, 1929-1932, 1988-1993 120 60 Years Life expectancy, median life and modal age at death, Switzerland from 1876 90 Men 80 70 50 Mode Median LE(0) 40 30 2006 1876-1880 1886-1890 1881-1885 1896-1900 1891-1895 1901-1905 1911-1915 1906-1910 1921-1925 1916-1920 1926-1930 1936-1940 1931-1935 1946-1950 1941-1945 1951-1955 1961-1965 1956-1960 1971-1975 1966-1970 1976-1980 1986-1990 1981-1985 1996-2000 1991-1995 2001-2002 Cheung et al, Japan 1980-1984 10000 9000 Halley 1687-1691 8000 Sweden 1754-1756 Switzerland 1876-1880 7000 Japan 1950-1954 6000 Japan 1980-1984 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Japan 2000-2004 10000 9000 Halley 1687-1691 Sweden 1754-1756 8000 Switzerland 1876-1880 7000 Japan 1950-1954 Japan 1980-1984 6000 Japan 2000-2004 5000 4000 3000 2000 1000 0 10 20 30 40 50 60 70 80 90 100 110 120 Compression of or shift in mortality ? Increase in the modal length of life (M), since 1751: a selection of 7 countries 95 90 85 80 Denmark England France 75 Japan Netherlands Sweden 70 Switzerland 65 60 55 1751 1776 1801 1826 1851 1876 1901 1926 1951 1976 2001 Correlation between the modal lenght of life (M) and the mean deviation above (eM) in 4188 life tables since 1751, males and females – (HMD) 14 12 10 e(M) 8 6 4 2 0 60 65 70 75 80 Modal age at death 85 90 95 Correlation between the modal lenght of life (M) and the mean deviation above (eM) in 4188 life tables since 1751, males and females – (HMD) 14 12 10 e(M) 8 6 4 2 0 60 65 70 75 80 Modal age at death 85 90 95 Change in the modal length of life and in SDM+ for women in Japan from 1950-54 to 2000-2004 5000 1950-1954 1960-1964 d(x) function, life table 4000 100 1980-1984 1990-1994 3000 2000-2004 9 2000 1000 8 90 0 0 10 20 30 40 50 60 70 80 90 Age 7 80 SD(M+) (years) Modal age at death (years) Women 1970-1974 100 6 Mode SD(M+) 70 5 2000-04 1995-99 1990-94 1985-89 1980-84 1975-79 1970-74 1965-69 1960-64 1955-59 1950-54 Cheung and Robine, 2007 110 120 Change over time in the distribution of the ages at death in France since 1827, female - for 100.000 newborn 5000 Nombre de décès (dx) 4000 3000 2000 1000 0 0 10 1827 20 1847 30 1867 40 1887 50 1907 60 70 1927 80 1947 90 1967 100 1987 110 2007 120 Emergence of the centenarians & Strong increase in the numbers of the oldest old people Change in the number of centenarians in Europe vs Japan Japan 45000 40000 40000 35000 35000 Male Female Total Females Males Total 2010 2005 2000 1995 1990 1985 1980 2010 2005 2000 1995 1990 1985 1980 1975 1970 1965 0 1960 0 1955 5000 1950 5000 1975 10000 1970 10000 15000 1965 15000 20000 1960 20000 25000 1955 25000 30000 1950 30000 1945 Number of centenarians (100+) 45000 1945 Number of centenarians (100+) Fourteen European countries More than 40,000 centenarians in Japan in 2009 August 14, 2010 45000 Number of centenarians 40000 Centenarians in Japan 35000 30000 25000 20000 15000 Total 10000 Males 5000 Females 0 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 22 Change in the number of centenarians in Europe vs. Japan Japan 45000 40000 40000 35000 35000 Male Female Total Females Males Total 2010 2005 2000 1995 1990 1985 1980 2010 2005 2000 1995 1990 1985 1980 1975 1970 1965 0 1960 0 1955 5000 1950 5000 1975 10000 1970 10000 15000 1965 15000 20000 1960 20000 25000 1955 25000 30000 1950 30000 1945 Number of centenarians (100+) 45000 1945 Number of centenarians (100+) Fourteen European countries Europe vs. Japan Robine and Saito, in press Divergence, variability and uncertainty Divergence in life expectancy at age 65 24 Females 22 22 20 20 Number of years Number of years 24 18 16 18 16 14 14 12 12 10 10 1945 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 Denmark France Japan Spain Sweden USA Males 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 Denmark France Japan Spain Sweden USA Divergence in life expectancy at age 65 24 Females 22 22 20 20 Number of years Number of years 24 18 16 18 16 14 14 12 12 10 10 1945 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 Denmark France Japan Spain Sweden UK USA Males 1950 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010 Denmark France Japan Spain Sweden UK USA The centenarian rate in Europe Robine and Saito, 2009 Are centenarian people healthy people? • The few representative studies of centenarians have demonstrated that they are in relatively poor health with a significant proportion being bedridden and/or demented – only 1% of Italian centenarians are fully independent – none of them continued social or productive activities that could be considered as examples of successful ageing • On the other hand several studies suggested that these extremely old people were in relatively good health 5 or 10 years before (Christensen et al, 2008). Differential mortality must have eliminated the frailer dependant nonagenarians. Population estimates: 100 years Females Males Total 233 250 265 245 47 46 36 43 280 296 301 288 719 773 4841 5210 5722 Denmark 2005 2006 2007 • Are older people more likely to become 2008 centenarians because they are in better health France or because it is much 2005 4189 652 easier to survive today? 2006 4491 4949 2007 • In Denmark, where the number of centenarians is Japan increasing relatively slowly, the functional health status 2005 7674 1533 9207 of female centenarians (100) significantly improved over 2006 8991 1609 10600 9769 1766 11535 the last decade (Engberg et al, 2008). 2007 2008 12483 2232 14715 • On the other hand in Japan, where the number of centenarians has increased more than 3-fold every decade since the 1970s, occasional centenarian surveys demonstrated significant declines in the functional health status of Japanese centenarians. Prevalence of centenarians confined to the room • Are peopleSampling more likely to tobecome Year older Population % confined the room centenarians % bedridden size ratebetter Males Malesit is much Females because they are in healthFemales or because 1973 (1) 405 28.9 19.1 37.5 14.3 21.9 easier to survive today? 1975 (2) 548 39.1 38.5 46.8 15.4 25.7 (3) 1072 94.2 33.1 50.7 18.2 27.9 • 1981 In Denmark, where the number of centenarians is 1992 (4) 4152 13.2 36.5 59.8 21.2 36.6 increasing relatively the functional health status 1993 (5) 4802 59.9 slowly, 39.3 61.1 17.9 34.4 2000 (6) 13036 14.6 57,0 significantly 78,0 22.2 41.1 of female centenarians (100) improved over the last decade. Research reports •(1) Tokyo Onmetropolitan the other hand in Japan, where the number of institute of aging (1973) centenarians has increased more than 3-fold every (2) Center for development of elderly welfare (1976) (3) Japan Health promotion and Fitness (1992)occasional centenarian surveys decade since theFoundation 1970s, (4) Japan College of Social Work (1992) demonstrated significant (5) Japan Health promotion and Fitness Foundation (1993) declines in the functional (6) Japan Health promotion and Fitness Foundation (2002) centenarians. health status of Japanese The Five Country Oldest Old Project (5-COOP): Relationships between the level of mortality selection and the health status of the oldest old Denmark, France, Japan, Sweden & Switzerland Robine et al, Centenarians today: New insights on selection from the 5-COOP study. CGGR 2011 The oldest old support ratio World wide decline in the oldest old support ratio As the number of people aged 50-74 for each person aged ≥ 85 Mortality trajectory Mortality trajectory with age 1891-1898 1899-1903 1909-1913 1921-1925 1926-1930 1935-1936 1947 1950-1952 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 qx series, males 0,8 0,7 0,6 0,5 0,4 0,3 0,2 0,1 0 0 10 20 30 40 50 60 70 80 90 100 110 1891-1898 1899-1903 1909-1913 1921-1925 1926-1930 1935-1936 1947 1950-1952 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 1 0,1 0,01 0,001 0,0001 0,00001 0 10 20 30 40 50 60 70 80 90 100 110 120 1891-1898 1899-1903 1909-1913 1921-1925 1926-1930 1935-1936 1947 1950-1952 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 0,8 0,7 0,6 0,5 0,4 0,3 0,2 0,1 0 0 120 qx series, males qx series, females 10 20 30 40 50 60 70 80 90 100 110 120 1891-1898 1899-1903 1909-1913 1921-1925 1926-1930 1935-1936 1947 1950-1952 1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 qx series, females 1 0,1 0,01 0,001 0,0001 0,00001 0 20 40 60 80 100 120 140 Mortality trajectory… Tokyo, June 2004, females, n=517 1 Probability of death Vincent 0,8 Thatcher et al 0,6 0,4 IDL Th-K Database Vaupel et al 0,2 0 92 96 100 104 108 112 116 120 Robine & Vaupel, 2005 Mortality trajectory… Tokyo, June 2004, females, n=517 1 Probability of death Vincent 0,8 Thatcher et al 0,6 0,4 IDL Th-K Database Vaupel et al 0,2 0 92 96 100 104 108 112 116 120 Robine & Vaupel, 2005 Mortality trajectory… Tokyo, June 2004, females, n=517 1 Probability of death Vincent 0,8 Thatcher et al 0,6 0,4 IDL Th-K Database Vaupel et al 0,2 0 92 96 100 104 108 112 116 120 Robine & Vaupel, 2005 Mortality trajectory… Tokyo, June 2004, females, n=517 1 Probability of death Vincent 0,8 Thatcher et al 0,6 0,4 IDL Th-K Database Vaupel et al 0,2 0 92 96 100 104 108 112 116 120 Robine & Vaupel, 2005 Thank you for your attention! Experts' Seminar on Ageing and Long-Term Care Needs LSE, Friday, 20 May 2011 The longevity revolution Jean-Marie Robine INSERM, Paris & Montpellier, France Change in the distribution of ages at death for women in Japan from 1950-54 to 2000-2004 5000 1950-1954 1960-1964 1970-1974 d(x) function, life table 4000 1980-1984 1990-1994 3000 2000-2004 2000 1000 0 0 10 20 30 40 50 60 70 80 90 100 110 120 Age Cheung and Robine, 2007 Change in the distribution of ages at death for women in Japan from 1950-54 to 2000-2004 5000 1950-1954 1960-1964 1970-1974 d(x) function, life table 4000 1980-1984 1990-1994 3000 2000-2004 2000 1000 0 0 10 20 30 40 50 60 70 80 90 100 110 120 Age Cheung and Robine, 2007 There is no evidence that the maximum human life span has changed from what it was about a hundred thousand years ago… … If the human life span is really increasing, then, for example we might find that the oldest humans were reaching the age of 100 years in 1850, 115 years in 1900, and 120 years in 1950. This would be good evidence that maximum life span is increasing, especially if large numbers of people in each period reached these very old ages. Hayflick, 1996 Number of oldest old in Japan by 5-year age group Centenarian increase in Japan 100000 Number of centenarians Total 100+ 10000 Total 105+ Total 110+ 1000 100 10 1 1960 1970 1980 1990 Calendar year 2000 2010
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