Main version 1.6
Pos ID
Full name
A
B
HGNC_symbol
Status
HGNC approved symbol
Status of entry
C
D
E
F
G
H
I
J
K
L
M
N
O
HGNC_ID
HGNC_name
GeneID
UniProt_AC
UniProt_ID
Domain
MGI_symbol
MGI_ID
UniProt_AC_Mm
UniProt_ID_Mm
GeneTag
GeneDesc
Function
HGNC ID
HGNC approved name
Entrez gene ID
UniProt AC
UniProt ID
Pfam domains
MGI symbol
MGI ID
UniProt AC (Mm)
UniProt ID (Mm)
HGNC gene family tag
HGNC gene family description
Function
P
Modification
Modification
Q
PMID_function
R
Complex_name
PMID for information on class
and function
Protein complex
S
T
U
V
W
X
Target
Specific_target
Product
UniProt_ID_target
PMID_target
Comment
Target molecule
Target entity
Product
UniProt ID of targets
PMID for reference on target
Comment
Comment
New, Updated, since previous
release (initially empty)
ID AC position
General function, use standard
terms
Which modification the
function is targeted towards,
use standard terms
Use Complex_name from
Complexes table
E.g. histone, DNA, RNA
E.g. histone with residue
E.g. type of modification
Not used yet
Free text
HGNC - www.genenames.org; MGI - www.informatics.jax.org; Pfam - pfam.xfam.org
Example
Source
ACTL6A
New
HGNC
Manual curation
24124
actin-like 6A
86
O96019
ACL6A_HUMAN
LRR_4 PF12799 88-133
Actl6a
1861453
Q9Z2N8
ACL6A_MOUSE
INO80
INO80 complex subunits
Chromatin remodelling
cofactor
DNA methylation
HGNC
HGNC
HGNC
HGNC and manual curation
Uniprot (ID Mapping using AC)
Pfam
MGI (Homology) and manual
MGI (Homology) and manual
MGI (Homology) and manual
Uniprot (ID Mapping using AC)
HGNC
HGNC
Manual curation
9845365
Manual curation
npBAF, NuA4, SWI/SNF,
Ino80, SCRAP, WINAC
histone
H3K36
H3K36me
H2AZ_HUMAN
21239497
This is not a real example …
From Complexes
Manual curation
Manual curation
Manual curation
Manual curation
Manual curation
Manual curation
Manual curation
Complexes version 1.5
Pos ID
Full name
A
B
C
D
Group
Group_name
Complex_name
Status
Complex group
Complex group name
Complex name
Status of entry
E
F
Alternative_name
Protein
Alternative names
Proteins involved
Free text
G
UniProt_ID
Uniprot IDs of involved
proteins
(See description
below table)
H
PMID_complex
I
J
Function
PMID_function
K
L
M
Target
Specific_target
Product
PMID for reference on
complex composition
Function
PMID for reference on
function
Target molecule type
Specific target
Product
N
UniProt_ID_target
Target UniProt ID
O
PMID_target
PMID for reference on
targets and products
P
Comment
Comment
New, Updated, since
previous release
(initially empty)
Example
Source
5
HAT
HBO1
New
Manual curation
Manual curation
Manual curation
Manual curation
Manual curation
Manual curation
ING4 or ING5, KAT7/HBO1, MEAF6, and one of
JADE1, JADE2 and JADE3
EAF6_HUMAN, (ING4_HUMAN|ING5_HUMAN),
Manual curation
(JADE1_HUMAN|JADE2_HUMAN|JADE3_HUMAN)+,
KAT7_HUMAN
16387653
Manual curation
Use standard terms
histone acetylation complex
10438470
Manual curation
Manual curation
Use standard terms
E.g. which histone
Modifications to
target
Comma-separated
list
histone
H3, H4
H3ac, H4ac
Manual curation
Manual curation
Manual curation
H31_HUMAN, H31T_HUMAN, H32_HUMAN,
H33_HUMAN, H3C_HUMAN, H4_HUMAN
10438470
Manual curation
Manual curation
Free text
UniProt_ID - A comma-separated list of complex members, where a member either is a single ID, ACTB_HUMAN, or a list of IDs of alternative proteins
separated by “|”, (ARI1A_HUMAN|ARI1B_HUMAN). An ID can be followed by “?”, indicating that the member is facultative. A list can be followed by
“+”, indicating that more than one member of the list may be included.
Histones version 1.5
Pos ID
Full name
A
B
HGNC_symbol
Status
HGNC approved symbol
Status of entry
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
HGNC_ID
HGNC_name
GeneID
UniProt_AC
UniProt_ID
Domain
MGI_symbol
MGI_ID
UniProt_AC_Mm
UniProt_ID_Mm
GeneTag
GeneDesc
Complex_name
Targeted_by_protein
Targeted_by_complex
PMID
HGNC ID
HGNC approved name
Entrez gene ID
UniProt AC
UniProt ID
Pfam domains
MGI symbol
MGI ID
UniProt AC (Mm)
UniProt ID (Mm)
HGNC gene family tag
HGNC gene family description
Protein complex
UniProt ID of targeting protein
Name of targeting complex
PMID for reference on
annotation
S
Comment
Comment
New, Updated, since
previous release
(initially empty)
ID AC position
Example
Source
H2AFB1
New
HGNC
Manual curation
22516
H2A histone family, member B1
8474382
P0C5Y9
H2AB1_HUMAN
LRR_4 PF12799 88-133
H2afb1
HGNC
HGNC
HGNC
HGNC and manual curation
Uniprot (ID Mapping using AC)
Pfam
MGI (Homology) and manual
MGI (Homology) and manual
MGI (Homology) and manual
Uniprot (ID Mapping using AC)
HGNC
HGNC
From Complexes
From Main and Complexes
From Complexes
Manual curation
RIH
Histones / Replication-independent
Not used yet
Not used yet
Free text
ARP3B_HUMAN
Ino80