A2 Milk: Golden Opportunity for Dairy by Ken Rabas (Editor’s note: In this article we refer to the subject as “A2” milk. The firm which owns the patent and trademark rights is the a2 Corp. of New Zealand. ) A2 milk has been previously covered in The Milkweed, but let’s revisit this potentially important dairy consumption trend. A2 milk first came to public attention in 2007, with the release of Keith Woodford’s book, “Devil in the Milk.” Dr. Woodford is a Professor of Agri-Food Systems at Lincoln University, in New Zealand. Early on, Woodford absorbed plenty of criticism from New Zealand’s dairy industry. NZ dairy interests scorned his detailing perceptions regarding A1 milk’s potential human health negatives. In truth, Woodford merits commendation for researching and detailing the human health benefits A2 milk. He has a website at Lincoln University: https://keithwoodford.wordpress.com Woodford occasionally posts updates on A2 milk issues. Much of this article derives directly from Woodford’s posts, which generally cover recently released research about A2 milk matters. Woodford discusses both sides of A1/A2 milk issues. After several very interesting posts in 2010 and 2011, Woodford submitted no new posts until 2014. All milk was once A2, until a genetic mutation affected some European cattle thousands of years ago. Most cows in Asia, Africa, Isle of Guernsey, and parts of southern Europe produce A2 milk, but in the United States, Canada, New Zealand, Australia, and northern Europe the majority of the cows produce A1 milk. This issue isn’t so much of A1 versus A2. This problem is caused by the breakdown of A1 milk in digestion, to the small protein/peptide, beta-casomorphin 7, or BCM7, that repeatedly shows up were we also see adverse health issues. A2 milk does not and BCM7, and we do not see health problems related to it. A personal note for me, since I have been on A2 milk, I no longer have problems with phlegm. I used to have to quit drinking milk when I had a cold. Now I continue to drink my A2 milk, without any problems. Let’s quickly summarize the perceived human health benefits of A2 milk. (A more proper, in-depth discussion of the science behind A2 merits a followup article in The Milkweed.) Keith Woodford’s comments allowed us to catch up on the last several years work of A1 versus A2 developments. Just a brief review of the health issues that have been suspected of having links to A1 milk and BCM7, includes heart disease, type 1 diabetes, autism, and schizophrenia. BCM 7 also appears to complicate issues for people that suffer from various digestive disorders and auto-immune disorders, which would include Coeliac disease and Crohn’s disease. SIDS (sudden infant death syndrome), multiple sclerosis, and Parkinson’s disease have also been mentioned. Human health discussions of A2 milk’s importance begins with infants and mothers. During digestion A1 milk breaks down to BCM7. If BCM7 gets in the blood stream, it can cause problems. BCM7 gets in the blood stream when there is leaky gut syndrome, from digestive disorders, stress, or in the case of infants, until their digestive system becomes fully developed, at 2 or 3 years of age. It has been shown that BCM7 in a mother’s bloodstream passes to the nursing baby from mother’s milk, even though mother’s milk is A2A2. BCM7 can be tested for in both the blood and urine. Many of the health issues that appear to correlate with elevated BCM7 levels begin in early childhood. With SIDS it appears that the elevated opioid effect of BCM7 may lower the respiratory rate and possibly be a contributing factor. Anything that is associated with babies’ poor health is an emotional issue for parents and grandparents. The science behind A2 milk is very strong. But the dairy industry politics opposing A2 milk have been even stronger. The dairy industry politics assure that public funding for significant A2 milk research is kept as close to zero as possible. For that 10 — The Milkweed • February 2015 reason, almost all A2 milk research is labeled as inconclusive by most major dairy interests. But evidence against A1 milk grows with the release of each new research report. It is becoming increasingly more difficult for the dairy industry to say there is no difference between A1 and A2 milk. Following my research on A2 milk, my personal opinion is that all mothers and young children should drink A2 milk. That should be a high priority for all families, for the health and well-being of children. Let me explain these strong opinions about A2 milk. I became aware of A2 milk a dozen years ago, when Gearld Fry explained A2 issues following his visit New Zealand. In 2013, I reread Dr. Woodford’s “Devil in the Milk” and received a better understanding of the science behind A2 milk – important information missed during the first reading. Rereading that book afforded a better understanding of the science. The first week of January 2014, I did a Google search for Keith Woodford A2 milk, and found the above-mentioned post at Lincoln University. I read the posts from 2010 and 2011. With a four-month old son, the health information I read became both scary and emotionally charged. Young children and grandchildren compel us to think more deeply about food and environmental issues. So I hope readers will excuse my writing this article with emotion that may push beyond readers’ comfort zones. At the most basic levels: I believe that A2 milk offers a wonderful opportunity for the U.S. dairy industry. But in the likely future scenario of “out with the old, and in with the new,” we’ll witness controversy and collateral damage in our hidebound dairy industry. A2: tremendous future opportunity A2 milk offers great opportunity to improve the health and well-being of family members, friends, and neighbors. At our home, we have our own grass-fed, A2, real milk. Most people have to depend on what is in the grocery store. Currently no A2 options may be found on supermarket shelves for consumers. This needs to change. The only way a consumer can find A2 milk today, is to find a source of raw A2 milk … and decide whether to home-pasteurize, or not. Expect increased consumer interest in A2 raw milk, if the U.S. dairy industry doesn’t offer commercial A2 products. I’m not advocating raw milk, rather, I am encouraging the dairy industry to give future consumers what they will want, so they don’t have to turn to raw milk. Let’s expand our sometimes “dairy tunnel vision” to imagine A2 milk as a tremendous opportunity for the dairy industry. Australia has become the most successful market for A2 milk. And A2 milk sales are being conducted successfully in Great Britain. Those two countries – modern and English-speaking – can serve as valid “test plots” for the U.S. market. Last year, Dr. Woodford wrote three articles for the Fairfax NZ Sunday Star Times (August 24, 31, and September 7). That series updated and summarized A2 milk issues. I will be quoting heavily from these articles. From Woodford’s Aug. 24, 2014 article “Evidence that A1 beta-casein might be a human health issue has been available for more than 15 years. However the mainstream dairy industry has always fought against the notion that it might be important. Within the last year, The a2 Milk Company has also launched an infant formula, ‘a2 Platinum’. It is produced here in New Zealand by Synlait on contract to The a2 Milk Company, and is marketed in Australia, New Zealand, and China. Within New Zealand, the promotion has been limited, but in Australia it is clearly getting lots of traction … there is a flood of new research now being published in the international scientific and medical journals demonstrating the relevance of A1 beta-casein to human health. The underlying cause is that A1 betacasein digests to release a peptide (a protein fragment) which has opioid characteristics. The peptide is called beta-casomorphin-7, or BCM7. This translates as ‘a morphine-like fragment from beta-casein containing seven amino acids’. The effects are multifaceted and every month we are learning more.” In 2007, author Keith Woodford released “Devil In The Milk” – the book that brought to public attention the differences between A1 and A2 milk. A2 milk is expected to be sold in the U.S. later in 2015. “The key research which is bringing the betacasein issue back to public attention right now has come from Curtin University’s School of Public Health. This research has demonstrated in a human clinical trial that A1 and A2 beta-casein produce statistically significant differences in digestive symptoms.” “I have always argued that for New Zealand the A1 versus A2 milk issue could be either a risk or an opportunity. Unfortunately, to a large extent we have squandered the opportunity – by ignoring rather than managing the risk – and now it is about to become a real risk.” “The way to get rid of A1 beta-casein is to breed cows that produce only the A2 type of beta-casein. It is easy to breed out the A1, but it takes time. Sheep, goats, camels, buffalo and humans only produce beta-casein of the A2 type. The A1 type is only in cattle and has been caused by a historical mutation.” “There is a lot more to be said about A1 betacasein, including specifics of the health implications, and the associated industry politics.” “The big message is that New Zealand should quickly get on with the task of breeding its dairy herds to be free of A1 beta-casein. Unfortunately, that will take at least ten years.” From Woodford’s August 31 article: “However, what has remained controversial until recently has been whether or not the BCM7 can pass through into the blood. Russian researchers have now shown quite clearly that it does pass into the blood of babies fed infant formula. They have also shown that a proportion of these babies are unable to metabolize the BCM7 efficiently between feeds and these particular babies have delayed psycho-motor (brain-to-muscle) development.” “Russian workers have also found BCM7 in the urine of all children on normal milk diets. Polish researchers have even found that mothers who are themselves drinking cow milk can pass bovine BCM7 to their babies in breast milk.” “The original evidence implicating A1 betacasein came from Professor Bob Elliott from Auckland University. He noted that Samoan children brought up in Samoa had a minimal level of Type 1 diabetes whereas children of Samoan ethnicity in New Zealand are vulnerable. He looked for differences in lifestyle, and identified exposure to cow milk as a possibility. Subsequently working with Dr Murray Laugesen, he showed that across the developed world more than 80% of the between-country variations in Type 1 diabetes could be explained by Continued on page 11 U.S. Imported Butter in 2014 from 9 Nations with Foot-and-Mouth Disease Problems Bad enough that Secretary of Agriculture Tom Vilsack wants to import beef from Foot and Mouth Disease-infected (FMD) nations like Brazil and Argentina. But in reviewing the nations that exported butter to the U.S. in 2014, we find a handful of nations with FMD problems. Somebody in Washington, D.C. is asleep at the switch on this one! In 2014, the U.S. imported butter from the following nations that lack FMD-free status by the World Organization for Animal Health: India, Israel, Egypt and Bangladesh. Further, the following nations have FMD regions that do or do not practice vaccination: Columbia, Argentina, Brazil, Turkey, and Philippines. In total, the U.S. imported 929,051.5 pounds of butter valued at $1,879,000 from FMD-infected countries during 2014. (See table.) FMD may survive in processed dairy products and meats (even frozen products) for up to seven weeks. Importing dairy products from nation’s with FMD problems is incredibly unwise. 2014 U.S. Butter Imports from FMD Nations Volume and Dollar Value Partner Colombia Argentina Israel(*) Brazil Philippines Egypt Bangladesh Total Product 040510 - Butter 040510 - Butter 040510 - Butter 040510 - Butter 040510 - Butter 040510 - Butter 040510 - Butter UOM Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Source: USDA Foreign Agricultural Service GATS database Value (1,000) $752 $666 $228 $120 $63 $29 $21 $1,879 2014 Qty 414,464.80 313,714.60 94,015.20 61,411.30 20,280.10 20,716.60 4,448.90 929,051.50 2014 U.S. Butter Imports By Nation, Volume and Dollar Value (1,000) 2014 Partner World Total Ireland France(*) New Zealand(*) Australia(*) Germany(*) Denmark(*) India Colombia Argentina Poland Italy(*) United Kingdom Mexico Netherlands Belgium-Luxembourg(*) Israel(*) Costa Rica Lithuania Portugal Brazil Finland Turkey Canada Czech Republic Philippines Egypt Bangladesh Greece Grand Total Product 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 040510 - Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter Butter UOM Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Lbs.* Value Qty 68,203 28,948,710.60 30,704 11,978,839.60 13,986 5,091,347.30 11,695 6,754,830.50 2,809 1,388,009.50 1,451 664,451.00 1,181 334,689.10 1,082 448,486.20 752 414,464.80 666 313,714.60 545 213,500.10 527 177,986.20 483 122,602.20 400 211,915.00 317 149,019.90 251 101,411.60 228 94,015.20 225 125,662.20 154 61,188.70 122 35,853.40 120 61,411.30 112 72,284.40 94 25,064.10 93 28,853.80 92 33,069.00 63 20,280.10 29 20,716.60 21 4,448.90 3 595.2 68,203 28,948,710.60 A2 Milk: Golden Opportunity for Dairy, con’t Continued from page 10 per capita intake of A1 beta-casein. Corran McLachlan showed similar correlations between intake of A1 beta-casein and heart disease. The correlations are statistically very strong and no alternative explanation for these between-country differences has stood the test of time.” “The New Zealand ‘AgRats’ study also found, as expected, that the opioid effects of BCM7 from A1 beta-casein slowed down the passage of food through the rat intestines. Intriguingly, the A1 beta-casein also significantly increased the release of an enzyme called DPP4. The reason this is so intriguing is that the modern gliptin drugs, now widely used to control Type 2 diabetes, act by inhibiting this enzyme, whereas with A1 beta-casein the level increased.” “There is a lot more research of relevance, including arterial plaque in rabbits and increased antibodies to oxidized LDL in humans. I now have several hundred published studies of relevance in my database. There is also a stream of additional studies in the pipeline about which I am very excited. There is no chance this issue will go away.” From Woodford’s September 7 article: ”Farmers can increase the rate of conversion by a range of active decisions. The most powerful is to genetically test each calf at birth and select replacements accordingly. Many farmers already genetically test their calves for other reasons, so adding the available test for A1 beta-casein is easy.” “A second strategy is to test the cows. This can have some effect through more effective culling, but is less powerful than testing the calves.” “The other way to greatly speed up the conversion is to use sex-selected semen. This would allow all existing A2 cows to produce female A2 progeny. This system works very well in intensive year-round mating systems used overseas, but needs further refinement for New Zealand’s seasonal mating systems.” “The concern about damage to the ‘existing category’ remains a key constraint influencing industry decisions. It is also an issue many politicians would prefer not to face up to. The alternative perspective is that it is better to manage risks pro-actively.” “Patents, which are not effective in New Zealand, run out in most other countries starting in 2016. So we have less than two years to build our lead. Thereafter, other countries, and particularly the USA with its mega-sized herds and the use of sex-selected semen, can quickly catch up, and race ahead with differentiated A1-free premium products. Oh dear!” Did any readers see the same, potential huge opportunity for the U.S. dairy industry that I saw in Woodford’s comments? Now I will share some of the things that I discovered as I looked into Holstein A2 genetics available in the U.S. I only looked at the Holstein population. ALL of the AI studs that I looked into have A2 DNA tests for their bulls. Surprisingly, many popular sires of sons the last several years have been A2A2. Thus, the U.S. dairy industry at this time has a much higher level of A2 genetics than Keith Woodford thought. In fact, one of the larger U.S. studs shows that over 50% of their bulls are A2A2 only 10% A1A1 for a 70% A2 gene total. 2 other studs were also well over 50% A2. The A2 DNA test is available from both the University of California-Davis, and GeneSeek in Lincoln, Nebraska. I have used the GeneSeek lab, the test is $12/animal, and there #is 402-435-0665. That test requires about 30 hair follicles from tail hair; also, the animal should be at least 6 month old. (Younger animals can be tested, but require a blood sample instead of a tail hair sample.) Last January I was faced with a dilemma: what to do about my growing knowledge of A2 milk, and how to help people, especially the people closest to me? I live in what’s called the largest Amish community west of the Mississippi River. Almost all of those families drink milk direct from the farm, so I set out to spread the word among my neighbors. I challenge each farm to test half a dozen cows – at a total cost of well under $100. Testing a half dozen milk cows should reveal at least one or two A2A2 cows. Some neighbors are finding more. Then: the only milk that goes to the house is from A2A2 cows. I would urge any dairy farmers drinking their own herd’s milk to do the same for your family, employees and their families. Taking A2 beyond dairy dinner tables The dairy industry has built a huge infrastructure to produce Whole Milk Powder, (WMP). But right now U.S. processors cannot market the volume of powder anywhere near what they’ve intended to produce. Domestic and global demand for U.S.-produced WMP is stagnant. A2 Whole Milk Powder, for infant formula or just a stable marketable A2 milk product for the general public, could be a way to bring the WMP industry back to profitability. As Keith Woodford, said, the evidence against A1 milk is mounting and the issue isn’t going away. The dairy industry is one angry parent away from a lot of bad publicity. If one very upset parent starts asking questions about why their sick baby has such elevated levels of BCM7 in their blood, asks were BCM7 comes from, goes to the internet, and says, “Oh, no! I drank the wrong milk,” and turns to social media. Look out. Remember what pink slime did to IBP. BCM7 is much bigger than pink slime. Let’s make some changes, so this never happens. Organic dairy producers in the U.S. deserve commendations, because since the 2007 release of “Devil in the Milk,” organic dairy farmers have been paying attention to A2 and are changing their genetics. There are 35-40 organic dairy farmers in my community, and virtually all know about A2 milk. We still have work to do, but everyone is aware. Last winter, in a conversation with one of the larger conventional dairy farmers in the community, he was asked about A2 milk. Answer: “What’s that?” … along with a confused look. No “bad case scenarios” of this sort need happen, if the U.S. dairy industry refocuses dairy cattle genetics and works to eliminate the A1 gene from our nation’s dairy herd – all in tandem with a wellcoordinated marketing program. If there is no A1 milk, there is no BCM7 in children’s blood. And we never have to hear about it again. The U.S. dairy industry could have a role in improving the overall health and well-being of their consumers … our proclaimed goal, eh??? Let dairy, through A2 milk, become a “farm-acy” for improved human wellness! The a2 Corporation of New Zealand has announced that it intends to re-enter the U.S. market in 2015. Several years ago, the initial effort in the U.S. bombed. Thus, the advent of commercial A2 sales may be soon. The a2 Corporation of New Zealand owns both the testing technology and has intellectual property rights over A2 milk. Whenever and however A2 milk arrives as supermarkets in the U.S., let’s hope that it’s an opportunity that may be widely shared and enjoyed. Some day, A2 milk might be the “new Organic” … and if those cows gorge on a lot of grass and pasture … so much the better! More information is available at: www.a2milk.com or www.thea2milkcompany.com I would personally love to see the dairy industry become the farm-acy, helping our family, friends, and neighbors and maybe even the people I don’t like so much. The Milkweed • February 2015 — 11
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