Model User Guide Ver. 1.05 BUILDING THE ECONOMIC CASE FOR TOBACCO CONTROL: A TOOLKIT TO ESTIMATE ECONOMIC IMPACT OF TOBACCO USER GUIDE TO THE ECONOMIC MODEL December 2011 2|Page Model User Guide Ver. 1.05 Background to the project The Health Economics Research Group (HERG) at Brunel University, in partnership with London Health Observatory and Queen’s Medical Centre, University of Nottingham, was commissioned to develop an economic model to estimate the economic impact of tobacco. The model was intended to support commissioners, in health and local authorities, to consider the impacts of tobacco on a range of health and non-health outcomes measured in financial and non-financial terms. This economic impact of tobacco model builds on previous analyses of tobacco control and smoking cessation. Previous economic models of tobacco use typically consider the costs and benefits that are accrued from the use of a particular intervention (e.g. NRT) or alternatively attempt to estimate the economic impact of smoking to the National Health Service. Whilst many of these analyses are robust and well developed, arguably, they lack relevance to a commissioning audience as they often reported aggregated findings over the entire population, taking into account the lifetime impact of smoking. This latest model has been developed to support sub national/local commissioners and decision makers, and incorporates a number of modifications from previous analyses. Crucially, the model attempts to generate outcomes in the short, medium and long-term, allowing commissioners to estimate the short-term return on investment in tobacco control initiatives. Whilst longer term outcomes remain important, it is acknowledged that the current funding environment means that commissioners may be focussed on returns over a shorter period of time. Secondly, the model attempts to capture the impacts of tobacco beyond the impact on healthcare costs by capturing evidence on productivity losses. This will broaden the relevance of the findings to commissioners and stakeholders outside of healthcare, including local authorities and private sector employers. Finally, the model also attempts to capture the impact of passive smoking on adults and children. This has not been attempted in previous analyses and adds an extra dimension to the current model. Finally, the model considers the impact of a comprehensive tobacco control programme, coordinated at a sub-national level, in addition to smoking cessation interventions. This not only reflects best practice, in terms of reducing smoking prevalence and uptake but also reflect current policy initiatives which recognise the importance of promoting tobacco control alongside cessation. 3|Pa ge Model User Guide Ver. 1.05 Model features and data Based on feedback from the stakeholder consultation, the model is built in Microsoft Excel in order to ensure that it is readily available to commissioners. The model is pre-populated with data on population statistics and smoking prevalence using data from the Integrated Household Survey, coordinated by the Office of National Statistics. This constitutes the default data on the basis that it is held to be the most accurate national source of evidence on smoking prevalence. The model is intended to be an interactive tool, for use by commissioners and planners. As such, many of the parameters in the model can be amended to reflect local circumstances. These include local prevalence estimates, wage rates and absenteeism associated with smoking and the underlying quit rate. The model assumes that there exists an underlying ‘background’ quit rate occurring due to social norm changes and self-motivation amongst current smokers to quit, assisted or unassisted. The assumed default background quit rate is 2%. Note that ‘background quit rate’ refers to ‘overall quit rate’, and not the rate that is applicable to only those smokers who quit unassisted. The model allows the user to explore the impact of a collectively commissioned sub-national tobacco control programme as well as the provision of local tobacco control interventions. Subnational strategies aim to change social norms through a combination of education and awareness, health promotion activities and facilitating access to higher quality services. Domestically, current evidence is somewhat limited, although the regional programme co-ordinated across the North-East of England by FRESH, has resulted in smoking prevalence falling at a more rapid rate than the national average. International evidence suggests that tobacco control programmes co-ordinated over a significant sub-national geographic footprint can accelerate the reduction of smoking prevalence. On the best available data, we estimate that the presence of a sub-national programme coordinating a package of tobacco control interventions might increase the background quit rate from 2% to 5%. This increase in background quit rate from 2% to 5% is possible because sub-national programmes tend to increase the number of smokers who are motivated to access Stop Smoking services, which in turn increases the likelihood of them quitting permanently and also impact on the number of new smokers, through improved tobacco control. All of this effect is reflected in this increase from 2% to 5% in background quit rate. So, the model works on the basis of current smoking pool but allows for the increases in number of smokers both quitting unassisted and quitting with support from Stop Smoking Services due to sub-national programmes via the new background quit rate (i.e. 5%). This is so because the evidence base as to how many more smokers would access Stop Smoking Services if sub-national programmes were implemented is not 4|Pa ge Model User Guide Ver. 1.05 sufficiently robust to model the effect of sub-national programmes on the number of current smokers accessing Stop Smoking Services. The model allows the user to estimate the economic impact of tobacco on their local population varying the use of smoking cessation interventions and assuming the absence or presence of a subnational tobacco control programme. It is hoped that the outputs can be used to help inform local investment decisions relating to tobacco control. 5|Pa ge Model User Guide Ver. 1.05 Opening the model The model is built in Microsoft Excel, to ensure that it is easily accessible for commissioners. NOTE: the model includes ‘macros’ and as such the user will have to enable content prior to starting the model. This can be done by clicking the button in the header highlighted in the screenshot below. This will then open the model. This may take a short time during which you will see a message stating ‘Initialising Model.’ 6|Page Model User Guide Ver. 1.05 Introduction page The pop-up box has sheet tabs (highlighted in the figure below) which take the user to introductions, model structure, inputs and disclaimer. The first tab on the pop-up box is the introduction page. This provides an overview of the model as well as details on how this should be cited. 7|Page Model User Guide Ver. 1.05 Model structure The second sheet tab takes the user to the model structure. The model is a simple ‘Markov’ model which includes three states:- smokers, former smokers and death. The model considers the population of a specific region/area. The population is divided into current smokers, former smokers and non-smokers, who may enter the model if they take up smoking (‘new smokers’). The risk of developing any of the smoking related outcomes specified in the model varies according to which state an individual is in – i.e. a current smoker will have the highest risk of developing an adverse outcome, followed by a former smoker, followed by a non-smoker. Individuals can move between each of the health states each year. That is, in any given year an individual might start smoking, continue to smoke, stop smoking and become a former smoker or die. The model follows the cohort over an entire lifetime but also reports short and medium term outcomes as described below. 8|Pa ge Model User Guide Ver. 1.05 Input screen The input screen allows the user to specify what data is to be used in the model. This includes the population under consideration, smoking prevalence and the use of smoking cessation services. In most instances these inputs are populated automatically but the user can over—ride these default inputs. Selecting the population: the user can select their local population, categorised as top tier (subnational), second tier or third tier. Population data for these are already included in the model along with estimates of smoking prevalence. In the example below, we have randomly selected Salford in the North-West which results in the population of 184,000 and a smoking pool (i.e. current smokers) of just over 53,000. 9|Page Model User Guide Ver. 1.05 Use of NHS Stop Smoking Services: The model automatically calculates how many current smokers will access smoking cessation therapy provided by NHS Stop Smoking Services. Cessation therapy is categorised as monotherapy NRT, combination NRT, Buproprion or Varenicline all of which are provided in combination with behavioural support. The default allocation of smokers to each of these services is based on the best available evidence on current use at a national level. However, the user can easily over-ride these values and incorporate local values where these are known, either by incorporating actual numbers of service users or using the up/down buttons in the table. Use of other cessation therapies: the model makes an assumption about the proportion of current smokers who access cessation services without recourse to NHS Stop Smoking Services. Based on the best available evidence at a national level, this is assumed to be 17.2% of all smokers. This default figure can be changed to reflect local uptake where this is known. However, given the difficulties in estimating access to non-NHS services, this functionality is currently locked in the model and can only be changed by users with a password. (Details on how to obtain a password are provided later in the guide). The final row in the table summarises access to smoking cessation therapy provided by the NHS and privately. 10 | P a g e Model User Guide Ver. 1.05 Running the model Once the user is satisfied with the input values, simply click ‘Run Model’ to generate the outputs. The model takes around one minute to run on most computers, during which time you will see a screen which reports on the progress of the model run. 11 | P a g e Model User Guide Ver. 1.05 Outputs The outputs are reported at three intervals 1. Short-term, which summarises the outcomes over two years 2. Medium term, which summarises the outcomes over ten years 3. Long-term, which summarises the lifetime costs and outcomes. Furthermore, three scenarios are also included in the analysis: • • • Scenario 1 assumes that there are no NHS Stop Smoking Services made available and no subnational tobacco control programmes in place so any quitting results from self-motivation. Scenario 2 assumes that NHS Stop Smoking Services are in place, with smokers allocated to these services according to the user-defined inputs. However, this scenario assumes that there are no sub-national tobacco control programmes in place. Scenario 3 assumes that NHS Stop Smoking Services are in place and furthermore these are complemented by a sub-national tobacco control programme. 12 | P a g e Model User Guide Ver. 1.05 Short-term outputs The short-term outputs focus mainly on healthcare resource use and the associated costs. Outcomes included in the model include GP consultations, prescriptions and admissions to secondary care. In addition to this, passive smoking episodes, quitters and productivity losses are also reported. The final two columns of the table report the ‘savings’ that accrue from moving from Scenario 1 to Scenario 2 or 3. The example below, based on Salford in the North West, shows that NHS Stop Smoking Services result in a cumulative saving to the NHS over two years of over £300,000 compared to no intervention. The introduction of a sub-national tobacco control programme leads to a further saving to the NHS of almost £500,000 and results in an additional 2,000 quitters over two years. The tobacco control programme has benefits which reach beyond the health service notably, resulting in productivity gains of over £250,000 compared to the NHS Stop Smoking Service alone. 13 | P a g e Model User Guide Ver. 1.05 Medium term outcomes The medium term outcomes focus mainly on episodes of smoking related morbidity and their costs over a 10 year period. The model estimates the number of smoking attributable cases of lung cancer, CHD, COPD, MI and stroke and estimates the cost of managing these. Once again, the addition of a tobacco control programme on top of NHS Stop Smoking Services results in a significant saving, estimated to be in excess of £4M over 10 years, using our example of Salford in the North-West. 14 | P a g e Model User Guide Ver. 1.05 Long-term outcomes Finally, the long-term outcomes in the model focus on life expectancy, quality adjusted life expectancy (reported as a quality adjusted life years or QALYs) and lifetime treatment costs. The number of deaths attributable to smoking in the selected population is reported, along with the mean number of life years accrued by smokers in the population. Note, the life years does not equate to the life expectancy of the cohort but rather reflects the average number of years lived recognising the baseline age distribution of the population under consideration. Treatment costs reflect the lifetime costs of treating smoking attributable conditions – these exclude any costs not attributable to smoking. The pop-up table reports summary findings for each of the main outcomes at each interval. Further details are available by clicking on the ‘Export Data’ button which takes the user to the Excel worksheets used to generate the outputs. These include counts of admissions as well as costs and are presented in a way intended to be suitable for export to other packages, for example Microsoft Word. 15 | P a g e Model User Guide Ver. 1.05 Accessing the model The model is made freely available for use and can be downloaded at http://www.brunel.ac.uk/about/acad/herg/research/tobacco. Passwords to access protected aspects of the model are available from the contact listed below. Version control Note, some of the model inputs are time limited (e.g. population statistics) and may be updated when new data become available. As such, it is the user’s responsibility to ensure that they are using the latest version of the model. All versions made available for download will be clearly marked with a version number. Referencing the model The Health Economics Research Group at Brunel University developed this work in partnership with London Health Observatory and Queen's Medical Centre, University of Nottingham. This work was funded by Smoke Free North West, Fresh Smoke Free North East and Smokefree South West. Inputs from the Steering Group and stakeholders are acknowledged. For details on how to use this model, please refer to accompanying Report and User Guide. Also, read the disclaimer information before you use this model. The following citation is recommended: Trapero-Bertran M, Pokhrel S, Trueman P. An economic model of tobacco control version 1. Tobacco Free Futures, Fresh Smoke Free North East & Smokefree South West. December 2011. Disclaimer information This toolkit when available on the web can be freely accessed and used for building business cases for tobacco control. This is primarily intended for commissioners, public health professionals, subnational managers and policy-makers. The toolkit has been developed using the current best practice and available data, and while doing so, a number of assumptions have been made. It is the responsibility of the users to understand the workings of the model and accept the assumptions underlying it. The Project team and the sponsors, therefore, accept no liability for any adverse consequence arising from the use of this toolkit. The users are expected to acknowledge the source in any form of verbal and written communications. The accompanying report describes the underlying principles of this toolkit and therefore the users are strongly recommended to read the report and the User Guide beforehand. 16 | P a g e Model User Guide Ver. 1.05 Acknowledgement We would like to thank the members of the Steering Group: Ailsa Rutter, Andrea Crossfield, Fiona Andrews, Adam Lester-George, Paula Wheeler, Mike Lavender, Martyn Willmore and David Phillips, for their guidance throughout the project. We are also thankful to all those practitioners and professionals who participated in our Stakeholder Engagement Events and provided their feedback on various issues they would have liked to be addressed in this work. We particularly thank the following who attended a round table discussion in May 2011 to discuss the development of this toolkit and who have endorsed the need for a tool capable of assessing the impact of tobacco control at a sub-national level: Deborah Arnott, Martin Dockrell, Howard Reed, Robert West, Ann McNeill, Mike Robinson, Lesley Owen and Matthew Glover for their valuable inputs. We are thankful to Matthew Glover who reviewed the model internally. Project Team Brunel University- Paul Trueman; Subhash Pokhrel; Marta Trapero-Bertran University of Nottingham- Tim Coleman London Health Observatory- Bobbie Jacobson; Paul Deponte South West Public Health Observatory- Adam Lester-George Request to the users This toolkit may be subject to continuous improvement. If any problem is encountered or inconsistency is found, please report it to the project team by email. Contact details for further information Any further information on the model can be obtained from Dr Subhash Pokhrel at Brunel University. Dr Subhash Pokhrel ([email protected]). 17 | P a g e Model User Guide Ver. 1.05 Supplements: 1. MS Excel/Web-based toolkit: Economic model of tobacco control 2. User Guide: Economic model of tobacco control (this document) 3. Tobacco Control Economic Toolkit Background and Rational Report 4. Tobacco Control Economic Toolkit Technical Report Recommended citation: Trapero-Bertran M, Pokhrel S, Trueman P. An economic model of tobacco control version 1. Tobacco Free Futures, Fresh Smoke Free North East & Smokefree South West. December 2011. 18 | P a g e
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