2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) EVENT INFORMATION DESCRIPTION – Disease Detectives allows students to use their investigative skills in the study of disease, injury, health, and disability in populations or groups of people with a focus on the FOODBORNE ILLNESS for 2017. There is a three topic rotation for Disease Detectives: Environmental Quality, Population Growth, and Food Borne Illness – each on a two year rotation 2017-Some Causes of Food Borne Illness • • • • • • Bacteria Viruses Parasites Protozoa Natural toxins Other pathogenic agents (as Prions) Some Environmental Causes of Public Health Problems: • • • • • • • • • Air pollution , Smoking, Inducers of Asthma Flooding health problems, Drought problems Extreme heat, UV exposure Lead contamination, Pesticides, Chemical Spills Water pollutants, Heavy metals Ventilation pollutants Noise induced hearing loss Waste and toxic substance Food contamination Some Population Growth Causes of Health Problems • • • • • • • • • • • • Water Quality, Water Pollution, Water Demands Sanitation Needs Growth of Slums and Household Environment Environmental Degradation Air Pollution Infectious Disease Outbreaks Rapid Spread of Disease via Public Transportation and Air Travel Food Quality and Food Contamination Lack of food in poor nations vs. unhealthy fast food and drinks in technological societies Availability of health care for the poor and the aged People moving into uninhabited areas = new pathogens as Lyme Disease and Ebola 1 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) RULES – Rules are available from your Tournament Director. • 2017 should appear at the bottom by the page number. • BE SURE TO CHECK THE RULES for Event Parameters and suggested topics. • At www.soinc.org see the Event Information and Event Supervisor sections • Rules clarifications are available at www.soinc.org under event information. FORMAT – Disease Detectives may be exam based, station based, or a combination of both It is most often an inquiry-based written exam with 2-3 outbreak scenarios. Division C may do some statistical analysis-< 10% of competition. EVENT NEEDS ROOM TYPE – Classroom when run as an inquiry based exam or a room with tables if run as stations. HELPERS – 2 or 3 helpers are needed to proctor and grade in addition to the event supervisor. If possible it is beneficial to have volunteers who are assigned to grading and others assigned to ranking. This is especially true if the event is run in 2 or more sessions. This ensures that the grading process is continuous and rushed. EQUIPMENT – Any materials needed for the competition. • One exam per team • Grading keys for helpers • One answer sheet per team • Basic office supplies (pens, pencils, stapler, staple removers, etc.) TIME NEEDED FOR SETUP • If possible go by the event room prior (~1 hour) to the exam to properly arrange the room. • When run as an inquiry-based exam, all teams can compete at once if a large enough room is available. • You just need time to check in and distribute the exam and answer sheets. • This event usually takes a long time to grade so it is a good idea to run it early in the day. • Using an answer sheet helps to organize answers for students and makes grading quicker. PREPARATION FOR COMPETITION TIME-LINE FOR PLANNING - You will need to know the number of teams competing. • Teams consist of two students so plan accordingly. Be sure you have enough time to prepare the questions, answer keys, and answer sheets. • Writing a good exam takes time. If possible begin the writing process as soon as possible. • Possible sources of outbreak scenarios are o Morbidity and Mortality Weekly Report o Emerging Infectious Diseases o Journal of Infectious Diseases o Journal of the American Medical Association o New England Journal of Medicine ORGANIZING CONTENT – Be sure to cover the topics presented in the rules and give appropriate emphasis to each area. 2 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) WRITING QUESTIONS • Format and material of the Division B and C event is similar except that the level of reasoning and math skills should be consistent with the grade level. • Differences between the two levels should be reflected in both the type of questions asked and the scoring rubrics. Testing the process is most important – students are taught to relate the 10 step procedure to the scientific method. • Competitions may be written using actual data from an outbreak or it may be a hypothetical outbreak with hypothetical data. • Fill in or multiple choice questions are easier to grade. • Free response questions should have a rubric to assist in scoring. • The Science Olympiad website www.soinc.org has event information with training materials for students, and internet links which may assist you in writing questions. The CDC has information on their website www.cdc.gov/excite as well as previous exams. • The philosophy of Science Olympiad is that the competition be inquiry- based to emphasize process skills and mental challenges using suggested content. • Balance the content so that it reflects the content described in the rules. Students are expecting to see all of the topics listed in the rules to be reflected in the competition. • Develop questions which are easy to grade. • Multiple choice, matching, fill-in-the blank questions are preferable. They are quicker to grade and allows volunteers completely unfamiliar with the event to assist in grading. For example: Okay: List three things that are true of case control studies. • Although the question is limited to 3 responses there are more than three possible correct answers. The grader will have to be familiar with case control studies to properly grade all possible responses. This will likely take from a few seconds to several minutes. Better: Which of the following statements are true about this case control studies? Circle the letters of all that apply. a. Finding adequate numbers of controls can be difficult b. Not vulnerable to bias c. Exposure is determined by memory or records d. Requires little time to conduct e. Can study multiple outcomes f. Used when the population is not well-defined g. All of the above • • • The above question has a definite answer (a, c, d, f) and can be graded by anyone. There are also multiple ways to provide partial points which can help avoid the use of tiebreakers. Objective Questions require a letter or few words and can be graded quickly Free Response or Essay Questions require several words or a paragraph and take longer to grade. They are good questions to use as tie breakers. Answers to short answer questions should require no more than one to two sentences and be very specific. Including questions with multiple interpretations and are open to various answers can be very difficult to grade. For example: 3 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Disease detectives use three pieces of information to characterize an outbreak. What are they? Answer: person, place and time There are only three correct answers to this question. No others are acceptable. A grader with no knowledge of epidemiology could grade this question. • • • • For questions requiring calculations points should be given for both showing their work and the correct answer. Graphs and tables are good potential source of questions. Develop appropriate questions so that all ties can be broken. Be sure that all teams experience the same testing conditions. VARING DIFFICULTY FOR SUCCESS OF MANY - To allow most students to be successful, it may be a good idea to vary the difficulty of questions! ANSWER SHEET ORGANIZATION – Set up the answer sheet so it is easy for students to use and easy for your team to grade. Include team name, team number, student names, as well as a place to record raw score, rank, and points. Be sure you have enough answer sheets for each team. It may be a good idea to put team names and numbers on the answer sheets ahead of time. ANSWER KEY AND SCORING RUBRICS • Questions will be assigned point values. • Students will be ranked from highest to lowest score. • Ties will be broken by pre-determined tie-breaker questions. • Have extra answer sheets so your helpers can assist you in grade the competition. • Be sure each section is graded by the same person. RUNNING THE EVENT SET UP TIPS (Exam format) • Be sure you have a copy of the exam for each team. • It may be advisable to have a separate answer sheet for each team. • The answer sheet will provide ease of recording answers and speed up grading. CHECK IN TIPS– if possible, allow all teams to compete even if one or both members are late. They may need to miss some things but they can do part of the competition. • Check each team member for wrist bands or approved ID before giving teams their answer sheet. • Have extra pencils and direct students print their names on sheet. • Direct student to turn off all non-permitted electronic devices. You may wish to have them put in a designated spot, given to someone outside the room or placed in the student back packs at some to be stored at a designated spot in the room. • Allow each team to have only what is permitted in the Event Parameters. 4 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) TEST FORMAT: • Hand out test packet just before the event is to begin. • Give any directions needed. • Two or three helpers can do the proctoring. • If the event is run in sessions, begin grading after the first session. • Helpers can help with grading as long as there is consistency in grading. DEALING WITH PROBLEM SITUATIONS – have the cell phone numbers of officials • DISQUALIFICATIONS OF A TEAM SHOULD BE RESTRICTED TO SAFETY ISSUES, CHEATING, OR ABUSIVE AND UNSPORTSMAN-LIKE BEHAVIOR. • Be sure that tournament officials and coaches are notified of any disciplinary action. CHECK OUT TIPS • Be sure to get an answer sheet and exam from each team before you allow them to leave the competition. • Be sure the team number, team names and member names are present and legible. • Remind students to take all their backpacks and other possessions as cell phones. SCORING THE EVENT – DO NOT GIVE OUT RESULTS ANY TEAM OR COACH. CONSISTANCY IN GRADING – have the same person grade the same section for all teams. CHECKING MATH AND RANKING – Be sure to check the math and ranking for all teams so they are accurate. Scoring worksheets or computer programs may be available to help with ranking. BREAKING TIES – Break all ties and indicate on the student answer sheets and score sheet how the tie was broken. The DECIMAL METHOD is a good way to indicate the winner of ties. Example: If two teams have the raw score tie of 83 for, the winner of the tie gets 83.1 while the other teams gets 83.0. If several ties are broken, you have .1 to .9 to use. This also points out scores where ties were broken. SCORE SHEET – Fill in all information on the score sheet. Indicate how the raw scores are ranked – high score, low score or some other method. Be sure to include raw score, rank and points for each team. Explain how ties are broken. SCORE COUNSELING • Have your score sheet completed and signed before going to score counseling • Arrange student score sheets in rank order for quick checking. • Turn in answer sheets, a copy of the test and an answer sheet to the Score Counselor I hope these suggestions are helpful in organizing your tournament. Comments or new ideas are always welcome. Please send them to me at the following address. Karen L. Lancour 312 W. Bosley Alpena, Michigan 49707 [email protected] 5 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Examples of types of performance indicators that could be used in Division B and C events at various levels of competition. Competition Level Regional/State Division Division B (Middle School) List and recognize examples of different modes of transmission Division C (High School) Recognize differences between study designs and types of error. Calculate health-related rates (attack, incidence, prevalence, case fatality) Calculate measures of risk (e.g. relative risk or odds ratio) when given a description of the study design Calculate a simple relative risk and describe what it means Calculate measures based on data that is not given but that can be readily extracted. Interpret epi curves, temporal patterns and other simple graphic presentations of health data.. Recognize how gaps in information influence the ability to extend conclusions to the general population. List, discuss and recognize examples of disease causing agents (physical and biological) Do Statistical Analysis on Data for both Descriptive and Analytical Epidemiology Demonstrate an understanding and ability to use terms such as endemic, epidemic and pandemic; population versus sample, association versus cause. National Describe various types of prevention and control strategies (e.g. immunization, behavior change, etc) and situations where they might be used Understand how units affect the relative magnitude of a set of rates with different units. Recognize unmentioned factors that may influence results and types of error. Calculate appropriate measures of risk when given the study design Convert between rates with different basic units (e.g. incidence per 10000 persons/year to incidence per 100 persons/week). Complete tables when given all data needed to complete calculations. Propose a means to evaluate the effectiveness of an intervention or control program. Propose a reasonable intervention to a public health problem. Do Statistical Analysis on Data for both Descriptive and Analytical Epidemiology Recognize gaps in information 6 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Potential Types of Error in Data Collection (Div C) • False Relationships o Random Error - the divergence due to chance alone, of an observation on sample from the true population value, leading to lack of precision in measurement of association o Bias or systematic error in an epidemiologic study that results in an incorrect estimation of the association between exposure and health-related event • Non-Causal Relationships – “guilt by association” o Confounding – occurs when the effects of two risk factors are mixed in the occurrence of the health-related event under study - when an extraneous factor is related to both disease and exposure Random Error: • Is the result of fluctuations around a true value due to sampling variability • It can occur with data collection, coding, transfer, or analysis of data • Affects measurement in a inconsistent manner • Ways to reduce random error may include – increasing the sample size and reduce the variability in measurements Systematic Error: • Occurs when there is a difference between the true value (the population) and the observed value (the sample) • The error is in the system used for measurement so it occurs in each occasion hence systematic error • Conclusions drawn on this data will be inaccurate – too great or too little • Validity of a study depends upon the degree of systematic error – less error equals more validity o Internal validity – the amount of error in measurements including those for exposure, disease, and the association between these variables. o External validity –relates to the process of generalizing the finding of a study to the population from which the study is taken Types of Bias: Describe problems in how the study is organized • Selection bias – occurs when study subjects are selected for the study as a result of a third unmeasured variable which is association with both the exposure and the outcome. There may be association between diseases or between characteristics and a disease related to the admission to a hospital for those with a disease, without the disease but with symptoms, and those with only the characteristics of the disease. • Information bias – occurs from systematic error in the assessment of a variable. Examples are information bias, response bias, interviewer bias, recall bias Confounding: the co-occurrence or mixing of effects of extraneous factors • May lead to overestimating or underestimating the true association between exposure and outcome. • A confounding variable would be a variable (pollution) that can cause the disease under study (cancer) and is also associated with the exposure (smoking). 7 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Statistical Concepts for Disease Detectives Division C Some statics may be used at Division C – but it must be less than 10% of the competition. 2016 Statistics in Science Olympiad Disease Detectives Events – Division C Descriptive and analytic statistical methods are important in the life and health sciences and it is reasonable to expect competitors at the high school level to demonstrate a basic competency in these methods in events such as Disease Detectives. However, statistics is not a major component of the event and should not define the event. Many competitors will not have had statistics and event supervisors should use it like a habanero, sparingly if at all but with purpose. One or two short, well-placed questions are adequate. Key principles • Competitors should be able to use statistics – not do statistics. Competitors should not be expected to do lengthy calculations such as paired T-tests, life tables or analysis of variance using hand calculators. In real life, these are done with computers and statistical software packages such as SAS, SPSS or EpiInfo. • A more realistic approach would be to explain the study design and data collection methods and have competitors interpret printouts from one of the above programs, to use intermediate statistics such as standard deviations and population means to calculate test statistics or tell how changes in the value of intermediate statistics would affect final results. • Students should be provided formulas for all calculations and tables. It is reasonable to expect them to know which test to use, assumptions and limitations of each but not to memorize the formulas. • Interpretation and translation of statistics into plain language is a valid competency that fits easily into a multiple choice format. For example, “Which of the below statements best describes these results?” • Asking students to select a test or what test they would use to test a particular hypothesis is also appropriate. This question may be best suited for multiple choice unless graders have sufficient expertise to know which tests are clearly inappropriate and which are marginally appropriate and recognize the different names for identical tests. • Questions concerning statistics should be part of a larger scenario so that competitors can see how they fit into the larger analysis. • Free-standing questions on statistics just for the sake of including statistics into the competition are contrary to the intent of the event. Event supervisors should not feel compelled to include questions about statistics in the events if they do not fit into the larger picture. 8 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Statistical Concepts for Disease Detectives Division C Descriptive Epidemiology - deals with the frequency and the distribution of risk factors in populations and enables to assess the extent of a disease - the epidemiologist collects information to characterize and summarize the health event or problem • • • Used as a first step to look at health-related outcomes Examine numbers of cases to identify an increase Examine patterns of cases to see who gets sick and where and when they get sick Mean – average – sum of all the given elements divided by the number of elements. Means are typically reported when data are normally distributed. where sum of x scores and n = number of units in a sample Median - The median of a series of numbers is the number that appears in the middle of the list when arranged from smallest to largest. Medians are typically reported when data are skewed. For a list with an odd number of members, the way to find the middle number is to take the number of members and add one. Then divide that value by two. In our case, there are 9 numbers in the series. 9+1 = 10 and half of 10 is 5. The fifth number in the series is the median or 14. If the number of members of the series was even, the average of the two middle numbers would be the median. Mode - The mode is the number in the series that appears the most often. If there is no single number that appears more than any other number in the series, there is no value for the mode. Variance - measures how far the results are from the expected results Standard deviation - expresses how close the results are to each is the square root of the variance other - it 9 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) Standard error of the mean - standard deviation (sample standard deviation) divided by the square root of the sample size Confidence intervals of means - specifies a range of values within which the mean may lie. Z Scores for Commonly Used Confidence Intervals Desired Confidence Interval 90% 95% 99% Z Score 1.645 1.96 2.576 Analytic Epidemiology - the epidemiologist relies on comparisons between groups to determine the role of various risk factors in causing the problem Z-test - compares sample and population means to determine if there is a significant difference. It requires a simple random sample from a population with a Normal distribution and where the mean is known. The Z-test is preferable when the sample number n is greater than 30. The Z value indicates the number of standard deviation units of the sample from the population mean. The Z measure is calculated as: z = (x - m) / SE where x is the mean sample to be standardized, m (mu) is the mean and SE is the standard error of the mean. where s is the population standard deviation and n is the sample population size. The z value is then looked up in a z-table. A negative z value means it is below the population mean (the sign is ignored in the lookup table). T-test - An independent one-sample t-test is used to test whether the average of a sample differ significantly from a population mean, a specified value µ0 Paired T-test -The dependent t-test for paired samples is used when the samples are paired. This implies that each individual observation of one sample has a unique corresponding member in the other sample Chi-square - Any statistical test that uses the chi square distribution used to decide whether there is any difference between the observed (experimental) value and the expected (theoretical) value - Chi square test for independence of two attributes 10 2017 EVENT SUPERVISOR GUIDE – DISEASE DETECTIVES (B/C) McNemar test for paired data - McNemar's test is basically a paired version of Chi-square test – a form of chi-square (Χ2) test for matched paired data which is used to compare paired proportions. It can be used to analyze retrospective case-control studies, where each case is matched to a particular control. Or it can be used to analyze experimental studies, where the two treatments are given to matched subjects. Fischers exact test - a statistical test used to determine if there are nonrandom associations between two categorical variables Cochran Mantel-Haenszel summary odds ratio (often called the Mantel-Haenszel test) is a hypothesis test for association between two variables while controlling for one or more nuisance or control variables. Mantel and Haenszel proposed stratification techniques to account for confounding. 11
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