13th Annual University of Sheffield Medical School Research Meeting
Thursday 15th – Friday 16th June 2017
PROGRAMME
Day 1 - Thursday 15th June 2017
“Research Success: Having an Impact”
The Octagon Centre
09:00 – 11:30
Registration
Poster presenters to hang posters before 11:30 AM
11:30 – 13:00
Themed Poster Tours & Stand Visits:
Themed poster tours organised by Medicine, Dentistry & Health Research Staff
Association (MDHRSA) & Medical Postgraduate Society (MPGS):
 In vivo models
 Clinical
 In vitro models
 Disease pathology/diagnosis
 Qualitative research
 Translational
 Therapy
 Technical
11:30 – 12:15
Poster Tours – Round One
11:45 onwards Lunch (for tour hosts/attendees, speakers & sponsors only)
12:15 – 13:00
Poster Tours – Round Two
Student Union Auditorium
Chaired by Sarah Geere [Impact Consultant, Research and Innovation Services]
13:00 – 13:05
Welcome & Introduction – MDHRSA & MPGS Representatives
13:05 – 13:50
13:50 – 14:45
Plenary Lecture (Clinical/Healthcare/Industry) - “From Bench to Bedside via an IPO”
Richard Ross
Professor of Endocrinology & Head of Unit of Diabetes, Endocrinology &
Metabolism [Department of Oncology & Metabolism]
TALKS ON IMPACT TOPICS – SESSION 1
13:50 – 14:15
Policy – “Making Impact Through Your Research”
Michael Makris
Professor of Haemostasis & Thrombosis [Department of Infection,
Immunity & Cardiovascular Disease]
14:15 – 14:45
Clinical – “A Technological Journey Through Dignity”
Professor Wendy Tindale OBE
Associate of Lab4Living, Scientific Director [Sheffield Teaching
Hospitals NHS Foundation Trust], Honorary Professor [University
of Sheffield], Clinical Director [NIHR Devices for Dignity HTC]
The Octagon Centre
14:45 – 15:10
Refreshments
Delegates can visit posters, industry stands & internal stands including:
 3Rs & Biological Services
 MDHRSA/MPGS/Think Ahead
 Medical School Postgraduate Team
Student Union Auditorium
15:10 – 16:50
TALKS ON IMPACT TOPICS – SESSION 2
15:10 – 15:35
Industry & Collaboration – “The Impact Of Industrial Collaborations
On Academic Research“
Dr Laura Ferraiuolo
Lecturer in Translational Neurobiology [Sheffield Institute for
Translational Neuroscience]
15:35 – 16:00
Patents – “The importance of patent to an academic researcher”
Dr Helen Bryant
Senior Lecturer [Department of Oncology & Metabolism]
16:00 – 16:25
Policy – “How DAFNE changed practice in the management of type
1 diabetes”
Professor Simon Heller
Professor of Clinical Diabetes [Department of Oncology &
Metabolism]
16:25 – 16:50
Parliament – “The Effect Of Research On Tobacco Policy In The UK”
Rt Hon. Kevin Barron MP
Labour MP for Rother Valley, Chair of All Parliamentary Pharmacy
Group, Co-Chair of the Associate Parliamentary Health Group
16:50 – 17:00
Closing Remarks – Sarah Geere [Impact Consultant, Research and Innovation
Services]
The Octagon Centre
17:00 – 18:00
Wine reception & Poster Bay Tours
Day 2 - Friday 16th June 2017
The Octagon Centre
08:45 – 09:00
Registration for Oral & Poster Presenters
Student Union Auditorium
09:00 – 09:10
Welcome & Introduction
Professor Dame Pamela Shaw [Faculty of Medicine, Dentistry & Health Pro-ViceChancellor]
SESSION 1:
09:10 – 10:30
Chaired by Professor Alison Condliffe [Department of Infection, Immunity &
Cardiovascular Disease]
Co-chaired by Daniëlle de Ridder
09:10 – 09:30
09:30 – 09:40
09:40 – 09:50
09:50 – 10:00
10:00 – 10:10
10:10 – 10:20
10:20 – 10:30
Invited speaker
Professor Jon Sayers – Personal Chair in Molecular Medicine & Deputy
Head of Department [Department of Infection, Immunity &
Cardiovascular Disease]
“Mechanistic Enzymology and an "X Files” Plot Line: Generating Branched
DNA to Kill Bacteria”
Dr Peter Novodvorsky [Department of Oncology & Metabolism
Clinical Lecturer in Diabetes]
“Risk of cardiac arrhythmias and electrophysiological responses during
spontaneous hypoglycaemia and hyperglycaemia in young people with
Type 1 diabetes”
Emma Smith [Department of Neuroscience]
PhD Student – 3rd Year
“The role of mitochondria in C9orf72-ALS/FTD”
Hannah Isles [Department of Biomedical Science]
PhD Student – 3rd Year
“Pioneer neutrophils initiate the swarming response to tissue injury in
zebrafish”
Dr Jessica Johnston [Department of Infection, Immunity & Cardiovascular
Disease]
Post-Doctoral Researcher
“Myeloid expression of Trib1 regulates the polarisation state of tissue
resident macrophages that has consequences on plasma lipid and
metabolic homeostasis”
George Pickering [Departments of Oncology & Metabolism & Infection,
Immunity & Cardiovascular Disease]
BMedSci Student
“Kif26b is necessary for osteogenic trans-differentiation and matrix
mineralisation in an in vitro model of pathological ossification”
Claire Green [Department of Neuroscience]
PhD Student – 2nd Year
“Development of an in silico molecular model of TDP-43 dysfunction”
The Octagon Centre
10:30 – 11:00
TEA & COFFEE BREAK
Student Union Auditorium
SESSION 2:
Chaired by Professor Alison Gartland [Department of Oncology & Metabolism]
11:00 – 13:00
Co-chaired by Katja Vogt
11:00 – 11:20
11:20 – 11:30
11:30 – 11:40
11:40 – 11:50
11:50 – 12:00
Invited speaker
Professor Tim Skerry – Head of Department [Department of Oncology &
Metabolism]
“Development of small molecule antagonists of the Adrenomedullin-2
receptor for pancreatic cancer”
Dr Maria Fragiadaki [Department of Infection, Immunity & Cardiovascular
Disease]
Thomas-Berry & Simpson Fellow & KRUK Fellow
“ANKHD1 drives polycystic kidney disease via altering the JAK-STAT
pathway”
Ruth Thomas [Department of Oncology & Metabolism]
PhD Student – 2nd Year
“The role of neuropilin-1 and VEGF isoforms in soft tissue sarcoma and
their potential as predictive biomarkers of response to vascular-targeted
therapies”
Riccardo Manca [Department of Neuroscience]
PhD Student – 2nd Year
“White matter correlates of complex processing speed performance in
relapsing-remitting multiple sclerosis”
Dr Rahaf Issa [Department of Infection, Immunity & Cardiovascular
Disease]
Post-doctoral Research Associate
“Fighting bacterial skin infections with tetraspanin-derived peptides”
Keynote Speaker Introduction – Professor Dame Pamela Shaw [Faculty of Medicine,
Dentistry & Health Pro-Vice-Chancellor]
12:00 – 13:00
KEYNOTE LECTURE: “Insights into the molecular basis of Huntington’s Disease”
Professor Gillian Bates, Professor of Molecular Neuroscience [Institute of
Neurology, University College London]
The Octagon Centre
13:00 – 15:00
LUNCH, POSTER VIEWING, STANDS & NETWORKING
13:20 – 14:50
13:20 – 14:05
14:05 – 14:50
2nd Year Postgraduate Poster Presentation Assessment
Viewing of odd numbered posters
Viewing of even numbered posters
Student Union Auditorium
SESSION 3:
Chaired by Professor Stephen Wharton [Department of Neuroscience]
15:00 – 16:30
Co-chaired by Annabelle Chambers
15:00 – 15:20
Invited speaker
Professor Winston Hide – Chair of Computational Biology [Department of
Neuroscience]
"Translational Neurosciences: The road to data driven precision medicine"
15:20 – 15:30
Ben Ward [Department of Infection, Immunity & Cardiovascular Disease]
15:30 – 15:40
15:40 – 15:50
15:50 – 16:00
16:00 – 16:10
16:10 – 16:20
PhD Student – 3rd Year
“Neutrophil microvesicles are increased by high-fat over-feeding and
enhance monocyte recruitment to endothelial cells under disturbed flow”
Daniëlle de Ridder [Department of Oncology & Metabolism]
PhD Student – 2nd Year
“Bidirectional regulation of osteosarcoma associated bone formation by
exogenous and tumour-derived Sema3A”
Naside Mangir [Department of Materials Science & Engineering]
Clinical Research Fellow
“An estradiol releasing, proangiogenic mesh can improve biomaterial
integration in pelvic floor repair”
Jude Akinwale [Department of Oncology & Metabolism]
PhD Student – 4th Year
“Generation of a Longer-acting Clotting Factor VIII for Haemophilia A
Treatment”
Dr Shuang Feng [Department of Infection, Immunity & Cardiovascular
Disease]
Research Associate
“Mechanical Activation of NF-κB-Cezanne- HIF1α Signaling Drives
Atherosclerosis Initiation”
Dr Alexander McGown [Department of Neuroscience]
Research Associate
“The characterisation of an inducible demyelination zebrafish model to
aid the investigation and development of novel therapeutics in multiple
sclerosis”
16:20 – 16:25
Thank you by Dr Adrian Higginbottom [Chair of the Medical School Research
Meeting Working Group]
16:25 – 16:30
Presentation of Prizes:
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16:30 – 16:35
3Rs Poster Prize: Dr Kamar Ameen-Ali
MPGS/MDH RSA Twitter Poster Prize: MPGS/MDH RSA Reps
Sponsor Stand Passport Prize: Dr Adrian Higginbottom
Oral Presentation & Moderated Poster Prizes: Prof Gillian Bates & Prof Nigel Clarke
Closing remarks by Professor Nigel Clarke [Pro-Vice-Chancellor Faculty of Science]