Genetic Testing, Insurance Underwriting and Adverse Selection Pradip Tapadar University of Kent Global Conference of Actuaries, Mumbai, India 19-21 February, 2012 P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 1 / 27 Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 2 / 27 Introduction Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 3 / 27 Introduction Background Background Single-gene disorders: Huntington’s disease, Alzheimer’s disease. Multifactorial disorders: Cancer, Cardiovascular disease. The UK Biobank project: Over 500,000 recruited from England, Scotland and Wales. Age-range 40-69: Follow-up period 30 years. DNA extraction from blood sample as and when required. “The main aim of the study is to collect data to enable the investigation of the separate and combined effects of genetic and environmental factors (including lifestyle, physiological and environmental exposures) on the risk of common multifactorial disorders of adult life.” P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 4 / 27 Introduction Genetics and Insurance Regulations Genetics and Insurance Regulations Insurance underwriting and setting premium rates. Information asymmetry and adverse selection. Genetic risk, environmental risk and insurance. Insurance regulatory developments in the UK: 1997: HGAC asks Government to impose a moratorium. 1999: GAIC formed to scrutinise use of genetic tests. 2000: GAIC approves use of genetic tests for HD for life insurance contracts over £500,000. 2001: ABI withdraws all applications – agrees a 5-year moratorium. 2005: Moratorium extended until 2011. 2011: Moratorium extended until 2017. Q: Taking economic and epidemiological issues into account, under what circumstances is adverse selection likely to occur with sufficient force to be problematic? P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 5 / 27 Risk aversion Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 6 / 27 Risk aversion Basic assumptions Basic assumptions Consider an individual with: initial wealth: W ; exposed to an adverse risk with probability q; on adverse event would incur a loss: L; utility function U(w ), which is: ? an increasing function of wealth; ? with decreasing marginal utility. P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 7 / 27 Risk aversion Utility function U(W−L) Utility U(W) Utility function W−L W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 8 / 27 Risk aversion Expected utility of a gamble U(W) Expected utility of a gamble Expected utility U(W−L) Utility qU(W − L) + (1 − q)U(W) W−L W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 9 / 27 Risk aversion A risk-averse individual with insurance U(W) A risk-averse individual with insurance Utility U(W − qL) U(W−L) Fair premium qL W−L W−qL W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 10 / 27 Risk aversion Comparing insurance against a gamble U(W) Comparing insurance against a gamble U(W − qL) Preference for insurance U(W−L) Utility qU(W − L) + (1 − q)U(W) W−L W−qL W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 11 / 27 Risk aversion Tolerance for a higher than fair premium U(W) Tolerance for a higher than fair premium U(W − qL) Tolerance limit Utility qU(W − L) + (1 − q)U(W) Extra premium U(W−L) ∆ W−L W − (qL + ∆) Fair premium qL W−qL W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 12 / 27 Adverse selection Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 13 / 27 Adverse selection Uniform premium for all strata Uniform premium for all strata Suppose: There are two risk groups. Low-risk group’s risk of adverse event q0 . High-risk group’s risk of adverse event q1 . Suppose further: The insurer is not allowed access to private information, and is forced to charge the same average premium, q̄, for both groups. Q: Assuming that the insurance purchasers are aware of their own risk, under what circumstances will the low-risk individuals stop purchasing insurance, triggering adverse selection? P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 14 / 27 Adverse selection Within tolerance limits – no adverse selection U(W) Within tolerance limits – no adverse selection U(W−L) Utility q0U(W − L) + (1 − q0)U(W) Extra premium Fair premium ∆ q0L Average premium q×L W−q×L W−L W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 15 / 27 Adverse selection Outside tolerance limits – adverse selection q0U(W − L) + (1 − q0)U(W) U(W−L) Utility U(W) Outside tolerance limits – adverse selection Extra Fair ∆ q0L Average premium q×L W−q×L W−L W Wealth P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 16 / 27 A Simple Two-state Model Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 17 / 27 A Simple Two-state Model The Model The Model λ - A B Model assumptions: Insured event represented by transition from state A to state B. Two risk groups with different transition intensities λ. Relative risk: k = λ1 λ0 ⇒ q1 = 1 − (1 − q0 )k . Proportion of population in each risk-group is known. The threshold relative risk, above which adverse selection takes place, can now be analysed. P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 18 / 27 A Simple Two-state Model Threshold relative risk Threshold relative risk 3 4 q0 = 0.5 1 2 q0 = 0.1 0 Threshold relative risk 5 50% in low−risk group 0 P Tapadar (University of Kent) Loss ratio (L W) Genetics and Insurance 1 19-21 February, 2012 19 / 27 A Simple Two-state Model Threshold relative risk 8 6 4 q0 = 0.5 2 q0 = 0.1 90% in low−risk group 0 Threshold relative risk 10 Threshold relative risk 0 P Tapadar (University of Kent) Loss ratio (L W) Genetics and Insurance 1 19-21 February, 2012 20 / 27 A Simple Two-state Model Immunity from Adverse Selection Immunity from Adverse Selection 0.9 1 0.5 q0 = 0.1 q0 = 0.5 0 Threshold population The population proportions above which the low-risk group will buy insurance at the average premium regardless of the relative risk: 0 P Tapadar (University of Kent) Loss ratio (L W) Genetics and Insurance 1 19-21 February, 2012 21 / 27 A Simple Two-state Model Summary Summary Observations For low loss ratios, even small relative risks cause people to opt against insurance. At high loss ratios, threshold relative risk increases. A sufficiently high proportion of low risk individuals ensures that adverse selection never occurs whatever the relative risk. Higher risk-aversion ⇒ Higher threshold relative risk. Conclusions Adverse selection in the 2-state insurance model does not appear unless: purchasers insure a small proportion of wealth; the elevated risks implied by genetic information are implausibly high; the size of the low-risk stratum is unrealistically small. P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 22 / 27 Critical Illness Insurance Example Agenda 1 Introduction 2 Risk aversion 3 Adverse selection 4 A Simple Two-state Model 5 Critical Illness Insurance Example 6 References P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 23 / 27 Critical Illness Insurance Example A Critical Illness Insurance Model A Critical Illness Insurance Model λ12 (x) State 2 Heart Attack λ13 (x) State 3 Cancer * State 1 Healthy P Tapadar (University of Kent) λ14 (x) State 4 Stroke H @HH @ HH @ HH @ HH j State 5 Other CI @ λ15 (x) H @ @ @ @ λ16 (x) @ R State 6 Dead Genetics and Insurance 19-21 February, 2012 24 / 27 Critical Illness Insurance Example Heart Attack Rates Heart Attack Rates as a % of Total CI Rates 1 Male Female Ratio 0.8 0.6 0.4 0.2 0 0 10 20 30 40 50 60 70 80 Age (years) P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 25 / 27 Critical Illness Insurance Example Summary Summary Observations Critical illnesses other than heart attacks creates a minimum premium; . . . and dilutes the impact of genetic risk on heart attack. The threshold relative risks are much higher for males than females. Adverse selection appears to be possible only for smaller losses and extremely low levels of risk aversion. Adverse selection does not appear at all at realistic risk-aversion levels. Conclusions The results suggest that in circumstances that are plausibly realistic, private genetic information relating to risks only available to consumers does not lead to adverse selection. P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 26 / 27 References References References Macdonald, A.S. & Tapadar, P. (2010) Multifactorial Genetic Disorders and Adverse Selection: Epidemiology Meets Economics. Journal of Risk and Insurance, 77:1, 152–182 Macdonald, A.S., Pritchard, D.J. & Tapadar, P. (2006) The impact of multifactorial genetic disorders on critical illness insurance: A simulation study based on UK Biobank. ASTIN Bulletin, 36, 311–346 P Tapadar (University of Kent) Genetics and Insurance 19-21 February, 2012 27 / 27
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