Economic Evaluation of Health Interventions Basic Concepts Farid Abolhassani M.D. Resources Time and abilities of individuals Land and natural resources Capital Knowledge of production processes Money is not defined by economists as a resource in itself Economic Evaluation: Definition The comparative analysis of alternative courses of action in terms of both their costs and consequences Economic Evaluation Cost/Effectiveness Ratio InputA CostsA - CostsB InputB Program A Cost Conseq Comparator B OutputA ConseqA - ConseqB OutputB Analytic Techniques Analytic technique Measure of costs Measure of consequences Cost-Effectiveness Money units Analysis Physical units Cost-Utility Analysis Money units QALYs or DALYs Cost-Benefit Analysis Money units Money units QALYs Perfect Health 1 Health-related Quality of Life With program A B Without program 0 Death 1 Duration (Years) Death 2 DALYs Perfect Health Perfect Health 0 Health-related Quality of Life With program A B Without program 1 Death 1 Duration (Years) Death 2 Expected Death When to Use which Analytic Technique Analytic technique Indication Cost-Effectiveness Comparing programs that have the Analysis same outcomes Cost-Utility Analysis Comparing programs that have multiple outcomes related to both quantity and quality of life Cost-Benefit Analysis Comparing programs that have heterogeneous impacts on welfare Viewpoints for Economic Evaluation Societal viewpoint Stakeholders’ viewpoints – Government – Ministry of health – Public / private providers – Other sectors – ..... Discounting: Rationales Taking time preference into account Avoiding a paradoxical result: a justifiable health improving intervention should never be undertaken The Cost-benefit Approach To Decisions The major challenge of daily living: Should I do activity x ? Economists’ answer to this question: If B(x) > C(x) Then Do x Otherwise Do not do x End if B(x) and C(x) could always be expressed in monetary terms Reservation Price: Definition The minimum amount of money one asks to give up something Or The minimum amount of money one is ready to pay to benefit from something The Role of Economic Theory Many economists believe that: Useful insights into our behavior can be gained by assuming that we act as if governed by the rules of rational decision making. Common Pitfalls in Decision Making Ignoring implicit costs Failing to ignore sunk costs Focusing on only some of the relevant costs Common Pitfalls in Decision Making Ignoring implicit costs Failing to ignore sunk costs Focusing on only some of the relevant costs به سينما ميرويد يا . . . . منفعت 9000 هزينهيفرصت هزينه اياب وذهاب 1000 تنقالت 2500 لذت بليط 1000 دستمزد 5000 جمع 4500 جمع 6000 3000 10500 7500 مطبوع نامطبوع 1000 -2000 5000 Cost of Activity x Cost of activity x = Direct costs + Opportunity cost Opportunity Cost The highest valued alternative sacrificed in order to choose an option is called the opportunity (real) cost of that option The Benefit of Activity x Benefit of a pleasant activity = Direct Benefit + Reservation Price Benefit of an unpleasant activity = Direct Benefit – Reservation Price به سينما ميرويد يا . . . . منفعت 9000 هزينهيفرصت هزينهيمستقيم اياب وذهاب 1000 تنقالت 2500 لذت بليط 1000 دستمزد 5000 جمع 4500 جمع 6000 3000 10500 7500 هزينهرفتنبهسينما مطبوع نامطبوع 1000 -2000 5000 Common Pitfalls in Decision Making Ignoring implicit costs Failing to ignore sunk costs Focusing on only some of the relevant costs Sunk Cost: Definition Costs that are beyond recovery at the moment a decision is made Marginal Analysis Tomans / Number Marginal benefit of pizza 2000 1000 Marginal cost of pizza 0 1 - 500 2 3 4 Number Common Pitfalls in Decision Making Ignoring implicit costs Failing to ignore sunk costs Focusing on only some of the relevant costs Buick or Toyota? Cb = 100 + 0.05d Cost Cb Ct 500 Ct = 300 + 0.025d 300 100 0 4000 8000 distance The Invisible Hand Wholly unaware of the effects of their actions, self-interested consumers often act as if driven by what Adam Smith called an invisible hand to produce the greatest social good. Components of Economic Evaluation Costs – C1: Health care sector costs – C2: Patient and family costs – C3: Other sectors costs Consequences – Resources saved – Health effects: QALYs or DALYs – Benefits Benefits: Assigning Monetary Value Human capital approach Willingness to pay approach – Actual health change focus – Global WTP How To Use Cost-effectiveness Analysis? Possible Outcome in the Two-alternative Case Effectiveness of A vs. B Cost of A vs. B More Same Less More ? B B Same A A or B B Less A A ? A or B? Program A Program B Lives saved (E) 1382 1723 Cost (C) 1812 2622 C/E ratio 1.31 1.52 Incremental Analysis Program A Program B Incremental B-A Lives saved (E) 1382 1723 341 Cost (C) 1812 2622 810 C/E ratio 1.31 1.52 2.38 More Than Two Mutually Exclusive Alternatives Effect L M J K Dominant I H (status quo) Cost Dominated Extended Dominance Effect L J M K Cost More Than Two Mutually Exclusive Alternatives Effect L M J K I H (status quo) Cost Equity Considerations Costs – Viewpoints – Valuation of lost work time Preferences – Age weighting – Discounting – Valuation Distribution of costs and consequences Distributional Equity Economic Incidence: Upon whom does something fall? Economic Incidence Fiscal incidence Expenditure/utilization incidence Net-incidence
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