Biology Exam Review Name____________________________ EXAM STUDY GUIDE Date_______________ Period________ A. Macromolecules (PowerPoints A5 and A6) Cells and their organelles are made up of smaller building blocks called __________________. The 4 basic types of these are: ______________, _______________, _____________________, __________________________. Macromolecules are actually made up of even smaller subunits. Each subunit of a macromolecule is called a _________________. The macromolecules themselves are called ________________, because they are made up of many of these subunits. Lipids are made up of… Monomer (basic unit): _____________________________. Polymer (chain of units): lipids Specific examples: ______________, _____________________, and ____________________. Properties of Lipids caused by: _________________ (solid at room temp) vs. __________________ (liquid at room temp) ___________ head and __________ tail regions _______________________ (likes water) and _________________________ (doesn’t like or “fears” water) 1 3 Functions of Lipids are: 1. Make up the _______ _____________________, providing cell _______________ 2. Provide _______________________ (fat keeps body warm) 3. Long-term _______________ _________________________. Lipids are found in foods like: _________________________, ___________, ______________, __________ & ___________. The indicator test for lipids (to prove that a certain food has fats in it) __________ __________ test. Proteins are made up of (subunits) ______________ ______________. _______ different kinds!! Polymer (chain of units): Protein……..More specifically, a protein is called a _________________________. Functions of proteins are to ___________________ and __________________ muscle and tissue _______________________ are proteins that speed up chemical reactions! Their _____________ determines their _________________________ !!! Other examples of proteins are _________________ (treats diabetics) and ______________________ (attaches O2 to red blood cells.) Proteins are found in these foods: _____________, ____________, ___________________, _________, _______, ____________, ____________, and _________ _________________. The indicator test for proteins is _________________: turns from ___________ to ____________ if protein is present. Carbohydrates are made up of…Monomer (basic unit): ____________ ____________ (or _________________________________________( literally means 1 sugar) Ex.: glucose 2 Polymer (chain of units): complex __________________________ (or ____________________________-literally means many sugars) Ex.: starch, cellulose, chitin, glycogen ****remember….some words that end with ___________ means they are also sugars! _______________ carbs (simple sugars) are found in ___________ and __________, __________, ______________, and ______________. They are _______________ digested and give a __________ ___________ of ______________. __________________ carbs (like _________________) are found in ____________, __________, _______________, ______________, & _______________. They take __________________ to digest, and provide _______________ _________________. The indicator test for Carbohydrates are actually 2 different tests: 1. Simple Sugars: 2. Complex Carbohydrates: _________ solution Blue solution turns ________________ _______________ solution (aka:_______________) Turns from orange-red-brown to ___________-purple Nucleic Acids are made up of…Monomers (basic unit): _________________________ Polymers (chain of units): _________ (double strand) or ___________ (single strand). Its shape is called a ____________-_____________. _________________ &_______________ are credited with its discovery in the 1950’s. Function is to ________________ and ________________ your ___________________ information. B. Enzymes (PowerPoints A7 and A8) Enzymes are ______________ that ____________________________ chemical reactions. They cause change, so they are also called __________________________. Reactions can occur without enzymes, but they may take a really long time. Enzymes _________ the amount of energy needed for the reaction to take place. 3 Some enzymes can _____________ _______________ substances into smaller parts: Other enzymes can ___________________ substances that cells need: Each enzyme is _______________ for one substrate (the substance it binds to). The enzyme and substrate fit together like a _______________ and ______________. When the substrate and enzyme ____________, the enzyme actually __________ its _________ a little. 4 Once an enzyme has finished with one reaction, it’s ready for another. Enzymes are ___________________. Do enzymes ALWAYS work? __________ - There are two factors that can __________________ enzymes, or alter the enzyme’s shape and stop it from doing its job. They are: __________________ & ________. Their _____________ determines their _________________________ !!! Has the enzyme been destroyed? _____________! Denatured” does not mean the enzyme has been __________________. It has simply lost its ____________. Enzymes can be “re-natured.” If they are returned to normal ______________or (condition), they will regain _______________. Enzymes work ________ at an optimal _______________ and _________ level specific for that enzyme. **Not all enzymes function at the same ____________ or __________!!** _______________- enzyme in mouth Which ones work at the same pH? _______________- enzyme in stomach _____________________ & _______________- enzyme in intestines _________________________ Most enzyme names end with the letters -_______, that’s how you know it’s an ____________or ___________. 5 C. Cell Organelles (PowerPoint A9) 1. The _________________ is the region between nucleus and cell membrane containing _________________, a _______-________ fluid that surrounds all cell parts and keeps them ________________ inside the cell. 2. ____________________ are threadlike structures that allow a cell to ____________ by rotating and propelling the cell forward. 3. The ________________________ supplies the cell with most of its __________ in the form of _________ (adenosine triphosphate). This is why it is commonly called the “_____________________” of the cell. What is the purpose of folding the inner membrane of this structure? To ____________________ surface area for ________________ production during _______________________ cellular respiration. 4. ________________________ are the ________________ organelles in a cell, and they are not surrounded by a membrane. They are responsible for making ___________________, aka: _____________ _______________. 5. Commonly called the “_________________” or “______________” center of the cell, this structure contains the cell’s instructions, or ____________ (genetic material). 6 6. The cell ____________________ encloses the cell and _____________________ the cell interior. It also plays a role in the __________________ of particles into and out of the cell, and cell to cell ___________________. 7. The cell __________ is a thick layer that surrounds the cell membrane for extra _________________ and _____________________ support. It is typically made of _________________________. 8. ______________________ are green colored organelles that use ______________ energy to make carbon compounds that can provide the ________________with energy in a process called _____________________. The pigment that makes these organelles appear green is called ________________________. 9. This is a large, internal compartment of the cell that stores ________________, ions, ___________________, and _____________________. It also helps the plant cell keep its __________________ by filling up much of the empty space in the cytoplasm. 7 ***Label the following Animal, Plant, and Bacterial cell diagrams*** Summarize how the cell’s organelles interact to carry out the following functions: (Google it!!) 1. Energy production and use: _________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ 2. Transport of molecules: _________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ 3. Disposal of wastes: _________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ 4. Synthesis of new molecules: _________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ D. Prokaryotes / Eukaryotes / Microscopy (PowerPoints A10 and A11) There are two basic cell types: __________________________(simple cells) & __________________________(complex cells) No nucleus Has a nucleus No organelles Has organelles Cells are very, very small- about .1 – 1 µm Cells are much larger 8 Example: E. coli (a type of bacteria) Very small in size Example: Animal, Plant, Fungi, Protist very large in size compared to the size of the bacterium These structures are found in both types of cells: _________________________ (protein synthesis), ____________ & ____________ (genetic information) The shape of DNA in Prokaryotes is _________________________(called a _________________), compared to the ________________ _____________________ found in Eukaryotes! Microscopy Microscope Usage • Always carry the microscope with one hand on the _________ and one hand on the _________. • Always look to the _________when ____________________the objectives. • Always begin viewing specimen on the ________________ power, then work up. • The coarse adjustment must only be used on the _________________power. Use ____________ adjustment on higher powers. • To calculate total magnification of microscope: _______________________ X ________________________ (Eyepiece always ________x.) Example: If objective lens is set on 15x, what is the total magnification of the microscope? ____________ What is the purpose of using the more powerful scanning and electron microscopes to look at the different cell types? _____________________________________________________________________________ ______________________________________________________________________________________ E. Homeostasis & Cell Transport (PowerPoints A4 and A13) • Homeo – means “_________________” 9 • -stasis – means “______________________” • Therefore, homeostasis is an organism’s ability to _______________ its _____________________ ________________________ the _________________ in order to survive. Internal conditions must be kept at a constant state so that your _____________, ___________ __________, ___________________, and __________________ can properly function. 1. Temperature: Maintained on cellular level by _________________ in cells (water _________________ __________ in temperature) Maintained at the body level by _________________ and __________________ 2. pH • Body has chemicals called _______________________ that _____________ pH ________________. • Some body fluids need to be: – Acidic – _____________________ (gastric juice), ____________________ – Basic – ______________________, and _________________ 3. Blood Glucose Levels • Body maintains the correct amount of _______________ (glucose) in the blood by ____________ and ____________________ food, then using and ______________________ the products • _____________________ is a disease associated with the ____________________ to control blood _____________________ levels. • _____________________________ is when your blood sugar level is too high. • _____________________________ is when your blood sugar level is too low. • Blood sugar levels are controlled by _______________________- ___________________: decreases blood glucose levels ________________: increases blood glucose levels 10 4. Water Balance • Organisms are ______% - ______% water • Water is needed for maintaining correct ________________ and transporting __________________ throughout the body • However, too much water can be ________________ • The ________________ maintains its correct water balance through the __________ ___________________, called (_______________________). • Body maintains water balance primarily through ___________________________________ (by producing ___________________) Water Loss: There are several ways in which your body can lose water: ___________________ air, ______________________ through moist surfaces like the cornea (eye), ____________________, ________________, _____________________, _______________, _____________________, and _____________________. Water gain: There are three ways in which your body gets water: __________________, _____________ content of _________________, Tissue _______________________________. Water is important for homeostasis because: a. Makes a good __________________ . b. ____________________ temperature change, because it has a high specific heat capacity! c. Universal ___________________ many substances __________________ in it. d. _____________________ helps to dissipate heat. Cell Transport • It consists of 2 layers of __________________ with their tails pointed inward. These lipids are called _______________________________. Their heads are _____________________ (attracted to water) and tails are _____________________________ (repel water). 11 It also contains several different types of ________________________, ______________________ markers, and ___________________________. Types of Cell Transport • Passive Transport- this type of transport requires ___________ energy because particles travel from where they are _____________ concentrated to a __________concentrated area. They travel ________________the concentration gradient. There are 2 types of Passive Transport (diffusion) ____________________________ and _____________________________ 12 Types of cell membrane PROTEINS • Channel proteins are _____________________ in the cell membrane & have a _______________for materials to use to cross through the membrane. • Carrier proteins can change ______________ to move material from one side of the membrane to the other • Active Transport- this type of transport _________________ energy. Particles travel from __________ concentration to ___________ concentration. In other words, they move _____________________ or _________ the concentration gradient. __________________ Transport _________________ Transport ______________________ is when molecules move from high concentration to an area of low concentration. ______________________ is when water moves from high concentration to an area of low concentration. 13 Changes in Osmotic Pressures 10% NaCL 90% H2O ________________ _____________ No Net Movement Cytolysis _________________ Plasmolysis ENVIRONMENT CELL 10% NaCL 90% H2O ________________________________________________ 10% NaCL 90% H2O CELL 20% NaCL 80% H2O _______________________________________________ 15% NaCL 85% H2O ENVIRONMENT CELL 5% NaCL 95% H2O _______________________________________________ 14 F. Energy, Cell Respiration, and Photosynthesis (PowerPoints A15 and A16) The synthesizing of energy molecules is vital for maintaining _________________________ in an organism. __________________________ in cells make the energy molecule __________. This release of this molecule allows for the ____________ to function normally, thus allowing the _____________________ such as muscle, bone, & skin, to perform properly. This action allows _____________________ of the organism, find _______________and _______________(H2O), avoid __________________, make molecules such as __________________ for repairing or building muscles or _____________________ to strengthen our bones, or even to attract a _________________. Cellular Respiration Cell Respiration – _________________________ break down food to make ____________ (energy) ____________________________________________ are types of organisms which utilize cellular respiration. Formula: C6H12O6 + 6O2 _______________ 6CO2 + 6H20 + energy (heat and ATP) ______________________ What environmental factors might alter the rate of this reaction? ___________________________________ _______________________________________________________________________________________ How is energy stored in this system? __________________________________________________________ How is energy released in the system? _________________________________________________________ How is energy transferred within this system? ___________________________________________________ 2 Types of Fermentation are ___________ _____________ and ________________________ _________________________________– builds up in __________________ when they do no get enough _________________ muscle fatigue ____________________________ – yeast cells produce ______ and ethyl alcohol (a.k.a._________________). Aerobic AEROBIC CONDITIONS: (oxygen present) Cell Respiration _________ ATP vs. Anaerobic ANAEROBIC CONDITIONS: (no oxygen) Fermentation ______ ATP 15 Photosynthesis Photosynthesis – process _______________________ use to trap _______________ energy and build __________________________ (glucose) that store energy. Takes place in the ________________________. The green pigment is called _____________________________. Formula: 6CO2 + 6H2O + energy ______________________ C6H12O6 + 6O2 ______________________ What environmental factors might alter the rate of this reaction? ___________________________________ _______________________________________________________________________________________ How is energy stored in this process? __________________________________________________________ How is energy released in the process? _________________________________________________________ How is energy transferred within this system? ___________________________________________________ **How is energy transferred between Cellular Respiration and Photosynthesis? ________________________ ________________________________________________________________________________________ _______________________________________________________________________________________ Compare the different types of Anaerobic and Aerobic organisms that use these systems._____ ____________________________________________________________________________ ____________________________________________________________________________ G. CHROMOSOMES: (Powerpoint ) pieces of _______________ that carry _________________ (instructions for life) Normal human body cells have ____________ chromosomes (1 set of 23 from mom, 1 set of 23 from dad) These cells are called ____________________ because they have two sets of chromosomes. Chromosomes come in __________________ (ex. two #1s, two #2’s, two #3s) Chromosome pairs #1-22 are called _______________________________________. Chromosome pair #23 are the sex chromosomes Females = ___________ Males = ____________ A ______________________________ is a chart of a baby’s chromosomes. It can be used to determine the gender of the baby and to detect chromosome abnormalities. Example: 16 This baby is a ________________________ and has _________________ Syndrome (3 copies of chromosome #21). Other common abnormalities: ____________________________________________ = woman with only one X ______________________________________________ = man with XXY H. CELL CYCLE: how a cell grows and divides Interphase --------------------------------------------> Mitosis -----------------------------------------------> Cytokinesis Interphase: G1 (Growth 1) – cell ________________________ S (Synthesis) – chromosomes (DNA) ___________________________ so that each new cell can have a copy G2 (Growth 2) – cell prepares for _____________________________ Mitosis: Prophase – nucleus ____________________________, chromosomes ______________, spindle ___________________ Metaphase – chromosomes line up in the _______________________, attached to spindle fibers Anaphase – chromosomes _____________________; each half is pulled to opposite ends of cell Telophase – nuclei ____________________, chromosomes ____________________, cell membrane starts to pinch Cytokinesis: ______________________ divides, cell splits into 2 cells 17 OVERALL PURPOSE OF MITOSIS: _______________________ cell becomes ______________________________ cells. The daughter cells are _______________________ to each other and to the parent cell (chromosomes and chromosome number is unchanged). Mitosis is a type of _____________________ reproduction (offspring cells are identical to parent cell). Mitosis is used by some unicellular organisms to ____________________________ and by multicellular organisms to _________________ and to replace ___________________ cells. I. GAMETES: cells that unite during sexual reproduction; sperm and egg Have to have _______________ the number of chromosomes as a body cell (humans = ___________), so when they unite they can make a baby with the correct number Only a single set of chromosomes (one of each instead of a pair), so it is called a _____________________ cell Need to have ________________________ so that no two children are the same except for identical twins Process that makes gametes = __________________________________ Meiosis is the reason why sexually reproducing organisms have such genetic ______________________! Meiosis creates sperm and eggs with ___________________________________________ (different combinations of DNA): 1. During Step 1 above, pairs of chromosomes come together and ________________________ segments of DNA. This is called ________________________________________ and it creates new combinations of genes. 2. During Step 2 above, chromosomes line up in pairs. Each time this happens, they line up in different patterns. This is called _____________________ or ______________________________ assortment. 3. When a unique sperm meets a unique egg (___________________________________), the combination is even more unique. More sources of variation: 4. DNA can _________________________ before gametes are formed. 18 5. During Step 7 above, sometimes chromosomes do not separate like they should. This occurrence is called _________________________________________, and it leads to sperm and eggs having the wrong number of chromosomes. * If either of these events occur in the sperm or egg involved in fertilization, the baby may be affected. OVERALL PURPOSE OF MEIOSIS: _______________________ cell becomes ______________________________ cells. The resulting cells are _______________________ from each other and from the parent cell (different chromosome combinations and chromosome number is halved). Meiosis is a type of _____________________ reproduction (offspring cells are different from parent cell). Meiosis is used to make ___________________________. COMPARISON OF MITOSIS AND MEIOSIS: Type of Cell Division MITOSIS MEIOSIS Purpose # of cell divisions # of cells made # chromosomes per cell Type of Reproduction DNA: a macromolecule made up of subunits called ___________________________________. A nucleotide has 3 parts: a __________________ (deoxyribose), a ________________________________, and a ______________________________ (adenine - A, thymine - T, cytosine - C, guanine - G). The nucleotides form ________ strands that are connected by _____________________________ bonds and _________________________ (“double helix”). J. DNA Model 19 If thought of as a ladder, the sides are the alternating _____________________________________________ backbone, and the “steps” are complementary __________________________________. Base pairing rules: A pairs with _________, C pairs with __________ Give the complementary DNA strand to the DNA strand, C A G G T A. ANSWER: _________________ DNA REPLICATION: process that produces an _______________________________ of a DNA molecule Happens during the __________ part of interphase; must occur before cell _______________________ so that each daughter cell can have a copy of the parent cell’s DNA Steps: 1. weak _________________________________________are broken, separating DNA into two strands 2. new ____________________________ pair with the exposed bases and form new hydrogen bonds 3. new _______________________________ is joined together MUTATIONS: a _______________________ in the DNA code Often occurs when a mistake is made during DNA _____________________________ Includes ____________________________ changes (addition, deletion, or substitution) or chromosome defects Can be spontaneous (random) or caused by mutagens such as _____________________________________________ Only mutations in ________________________ (sperm, egg) will be inherited by children GENE EXPRESSION: the information in DNA (sequence of bases) is used to build a _______________________ K. TRANSCRIPTION: DNA is used to make a copy of _______________ What is RNA? A nucleic acid that differs from DNA in 3 ways: 1. 2. 3. ___________________ (U) instead of thymine (T) ___________________ sugar instead of deoxyribose __________________-stranded instead of double-stranded Transcribe this DNA strand: T A C C C G A G T G T G ANSWER: _________________________________ 3 major types of RNA: _____________________________ RNA (mRNA) – takes DNA code (“the message”) from nucleus to ribosome 20 ribosomal RNA (rRNA) – makes up part of ribosome _____________________________ RNA (tRNA) – transports ______________________________ to ribosome L. TRANSLATION: Messenger RNA is “read” 3 bases at a time to make a protein _____________________ = 3 bases that determines which amino acid will added to the protein mRNA = AUGGGCUCACAC (transcribed from DNA) Protein/Polypeptide = This protein synthesis process is similar for ALL organisms: All organisms use ________________________________ Transcription and translation are similar for all organisms All organisms use the same ________________________________________ Suggests that all organisms have a common _____________________________ Why are proteins important? Proteins can: Be __________________________ – forming cell parts, tissue (ex. collagen – skin), hair (keratin) Be __________________________ – hormones (ex. insulin), enzymes (ex. lactase), etc. Determine ______________________________________ (phenotypes) such as hair color In summary: ___________________________ DNA code --------------------------------------> (sequence of A, T, C, G) _________________________ mRNA code ---------------------------> PROTEIN (sequence of A, U, C, G) (sequence of amino acids) 21 What if the DNA code is changed (mutated)? The instructions for making the protein are __________________________. A single base change in DNA could change an __________________________________, which could ___________________________ the function of the protein or change the phenotype. Example: DNA code Original: CAG Mutated: CGG RNA code Amino acid DIFFERENTIAL GENE EXPRESSION: Proteins can be made in different ________________________, different ___________________, and in different cells. Overproduction of protein – injury repair, cancer Underproduction of protein – ex. diabetes Protein production in response to _______________________________ - tanning (melanin) M. CELL DIFFERENTIATION: process in which cells become different to make up different tissues, organs, etc. in multicellular organisms Nearly all cells in a multicellular organism have the same _______________ (coded instructions) Cells become different because only ______________________________ of the DNA is used (“active”) in each type of cell The parts of DNA that are activated determine the _______________________________________________ of the cell Process cannot be _______________________ (a differentiated cell cannot go back to being undifferentiated) Process of cell differentiation/specialization: FERTILIZATION: sperm and egg unite __________________________ is formed 22 Lots of _________________________ Ball of __________________________________ (undifferentiated cells that have the potential to become any type of cell) ___________________________________ = different genes become active in different cells, causing cells to vary in shape and function Basic genetic terminology and concepts: A ___________________ is a piece of DNA that codes for a protein/trait (ex. plant height) An organism receives ____________ copies of that gene (one from mom, one from dad) An ______________________ is a version of that gene (ex. tall and short) Often, one allele is _____________________ over the other (the dominant allele masks the RECESSIVE allele) Alleles are written using letters. The ____________ letter of the dominant trait is used for both alleles; the dominant allele letter is _______________________ and the recessive allele letter is ___________________________. o Example: If tall is dominant to short, tall is __________ and short is __________. A _______________________ is two letters representing which alleles an organism inherited from its parents If the two letters are the same, the genotype is considered _______________________________________. If the two letters are different, the genotype is considered ______________________________________. A ______________________________ is the outward showing of a trait (a written description). 23 Using phenotype to determine genotype and vice versa: Ex. Round peas are dominant to wrinkled peas. Ex. Purple flowers are dominant to white. Round peas ___________________ Heterozygous purple ________________ Wrinkled peas _________________ White _____________ Homozygous purple _______________ Ex. Yellow peas are dominant to green peas. YY ________________ yy ________________ Yy ________________ Punnett squares = way to solve genetic crosses between two parents to predict offspring N. Types of Inheritance/Genetics Problems: 1. Complete dominance (simple dominant/recessive) a. Rr x Rr (round is dominant to wrinkled) _____% round _____% wrinkled b. What is the result of a heterozygous round crossed with a homozygous round? ________ x ________ _____% round _____% wrinkled c. Which of the parents below produce offspring that were 50% round and 50% wrinkled? RR x Rr RR x rr Rr x rr rr x rr 24 d. _________________________ disease – dominant; breakdown of brain tissue ~ 30-50 years old HH ______________ Hh ______________ A man heterozygous for Huntington’s has a child with a hh _______________ normal woman. What’s the chance the child will have it? _____% chance e. systems ______________________ - recessive; accumulation of mucus in respiratory and digestive NN _______________ Nn _______________ nn ________________ Two carriers of CF have a child. What is the chance that the child will have CF? _____% chance NOTE: Only ____________________________ diseases can have carriers! Both Huntington’s disease and cystic fibrosis are called ___________________________________ because they affect men and women the same. 2. Incomplete dominance – results in the ________________ of traits (“____________________”) * example: black fur mice x white fur mice = _________ fur mice BB = ________________ What would the offspring of 2 gray mice be like? B’B’ = _______________ BB’ = ________________ _____% black, _____% gray, _____% white 25 * example in humans: ________________________________________ - fatigue, joint aches, shortness of breath AA – _____________ (no sickling) SS – _____________ (sickling) normal. Mom has SCA, dad is AS – _____________ (some sickling) 3. ______ x ______ being a carrier makes you more resistant to _____________________, which explains why SCA is more common among African Americans Co-dominance – results in expression of ________________ traits (ex. dominecker chickens) Multiple Alleles – there are __________________________ different forms (alleles) for the gene example in humans: ___________________________________ (alleles: IA, IB, i) IA and IB are co-dominant to one another, “i" is recessive Type A: __________________ Mom is AB, dad is O. Type B: __________________ ________ x _________ Type AB: ____________ Type O: ____________ Children: _________________ Can a man with type A blood and a woman with type B blood have a baby with O blood? 4. Sex Determination * the chance of a man and woman having a son (or daughter) is ALWAYS _________%!!! 5. Sex-Linked Traits – traits controlled by genes on the _______________ chromosomes Affects men and women differently!!! * If trait is on: - X and is dominant – more _________________ have it (ex. scoliosis) - X and is recessive – more _______________ have it (ex. baldness, hemophilia, colorblindness) - Y – only _____________ have it Ex. Hemophilia is a recessive disease carried on the X chromosome. N = ____________________________ n = __________________________________ 26 XNXN _____________________ XNY _____________________ XNXn _____________________ XnY _____________________ XnXn _____________________ A woman who is a carrier and a normal man have a child. What is the chance the child will have hemophilia? _________ x _________ Why is it that hemophilia is much more common in men?? 7. Polygenic Trait – trait controlled by _____________ genes; shows wide ________________ of phenotypes ex. hair color, eye color, skin color, height (humans) hard to predict! --------------------------------------------------------------------------------------------------------------------------------------_________________________ - family tree showing a trait or disease Common symbols: Determining inheritance patterns from pedigrees: 1. If trait or disease shows up in every generation, it is probably ____________________________. 2. If trait or disease skips generation one or more generations, or if a child has it and both parents do not, or if it shows carriers, it is definitely ______________________________. 27 3. If one gender has it a lot more than the other (ex. men have it and women are carriers), it is probably a _________________________________ trait. Determining genotypes from pedigrees: ex. Huntington’s disease ex. cystic fibrosis How environment can affect the expression of certain genetic diseases: Lung/mouth cancer – can be influenced by both “cancer” genes and ______________________ use Skin cancer – influenced by genetics of ________________ skin, sun exposure, and Vitamin D/folic acid (anti-cancer agents) Diabetes and heart disease – influenced by genes and _________________________________ PKU – genetic disease causes brain damage only if baby drinks _______________ products O. GENETIC TECHNOLOGY 1. __________________________________________________ - 1990 – 2003, many countries involved - purposes: ___________ and ________________________ all genes on the human genome - uses: ____________________ of genetic diseases, identifying ______________________ of genetic diseases, developing ___________________________ of genetic diseases (gene therapy) 2. ____________________________ – inserting a normal gene into the cell’s of someone with a defective gene used to treat cystic fibrosis and other genetic diseases gene is “inserted” using a __________________ shell 3. ______________________________ - technique used to separate DNA fragments based on size DNA is sample is cut into pieces with ______________________________________________ DNA is “loaded” into a gel and the gel is subjected to __________________________ charge DNA is negative and it travels toward the positive end Cut DNA fragments separate; ____________________ pieces travel farther through the gel The resulting banding pattern is called a DNA ________________________________, and because it is unique to the person, it can be used in _________________ and _________________ cases. It has also been used to identify missing persons and endangered species. 4. ______________________________________________________ = organisms that contain foreign DNA Agricultural applications o Plants and animals that contain DNA that is not their own are called ________________________________________________________ o Plants engineered to produce pesticides, frost-resistant crops 28 o Controversial because of unknown effects to humans and environment Medical applications o Bacteria engineered to produce human ________________________ o Process is called ___________________________________________________________ 5. ________________________________________________ Stem cells = cells that can become any type of cell (ex. heart, lung, skin) Two types: embryonic stem cells (from embryo) and adult stem cells (from bone marrow) Under correct conditions, stem cells may be able to differentiate into different kinds of __________________________________________, which may be used to treat certain human disorders Controversial P. THEORIES about early Earth and the evolution of life: 1. _________________________________________________ (1923) early Earth was very ____________; atmosphere contained inorganic molecules such as ammonia, hydrogen, water vapor, methane (very little ____________________________) high temperatures, UV light, and lightning converted inorganic molecules to simple molecules, then to more complex organic molecules such as __________________________________ when atmosphere cooled, organic molecules were washed into the oceans where life began supported by a 1953 experiment (see right) 1. first organisms must have been simple (______________________________) and did not require oxygen (____________________________) evolution of organisms most likely followed this pattern: prokaryotic __________________________ _____________________ (oxygen) aerobic eukaryotic & anaerobic eukaryotic cells are thought to have evolved from symbiotic relationships between bacteria = __________________________________________ theory 29 Primate % similarities between primate DNA and human DNA A 95.3% B 97.5% Q. EVOLUTION: change in a population over time Evidence for evolution: 1. _____________________ - trace of a long-dead organism o can tell us what kind of organisms existed at various times in Earth’s history, where they lived, their behavior, and extinctions Which fossil is oldest? ________ youngest? __________ Which fossil is about the same age as #1? ___________ 2. ______________________ - body parts o Some organisms have very similar bone structure. = suggests ___________________________________________! o Some organisms have structures with no present-day function (_________________________) (ex. ostrich wings, human tail bones) 3. _____________________________________ similarities o comparison of DNA, RNA, proteins Which primate is most closely 30 related to humans? _______________ C 94.8% Mechanisms for evolution (how it happens) 1. _______________________________________ (#1 cause) – survival of the fittest The theory of natural selection (proposed by Charles Darwin) states: o There must be ___________________________ in the traits of a population. o There must be environmental __________________________ that favors one variation of the trait over the other. (limited __________________________, predators, pollution, etc.) My pond: Organisms with the “better” traits will ____________________ better and longer, live to _______________________, and pass those good traits on to their offspring. The result will be an accumulation of “good” traits and a population better suited for the environment. My field: 2. __________________________________________ ________ - if the organisms in a population become separated by physical barriers, they will no longer reproduce and may become two separate species (________________________________) Current concerns with evolution o ___________________________-resistant insects o ___________________________-resistant bacteria o as our immune systems evolve to be stronger and we develop medicines, pathogens will evolve to overcome our defenses = ____________________________________ R. Classification, Phylogeny, and Dichotomous Keys (PowerPoint A31) _____________________ is the grouping of objects or information based on similarities. (aka taxonomy) 31 _____________________ is a branch of biology that ______________________________________ organisms based on their characteristics Taxonomists are scientists that _________________ & ________________ organisms • _______________________ & ________________________ names organisms • Prevents ____________________________ such as starfish & jellyfish that aren't really fish • Uses same __________________________ (Latin or some Greek) for all names • The way we classify organisms ___________________ as we gather ______________________ about: • ___________/__________________ analysis • ______________________________- study of an organism’s early stage of life • _____________________ (body parts)/____________________________ (form) • ________________________- evolutionary ______________________ of an organism • ____________________________________ is known as the “father” of modern taxonomy. • Developed the modern system of naming known as _____________________ ___________________ • Two-word name (_________________ & ____________________) Classification of a human: D____________________ (3) – group of similar kingdoms (Eukarya) K____________________ (7) – group of similar phyla (Animalia) P____________________ - group of similar classes (Chordata) C____________________ - group of similar orders (Mammalia) O____________________ - group of similar families (Primates) F____________________ - group of similar genera (Hominidae) G____________________ - group of similar species (Homo) S____________________ - a group of organisms that can interbreed and produce fertile offspring in nature (H. sapiens) The following are examples of a Cladogram and a Phylogenetic tree. 32 A B C D E F Cladogram Phylogenetic Tree Which appeared first in history? Which 2 are more closely related? A. Salamander B. Lamprey A&D C. Wolf D. Vertebral Column B&F E&F D&E Which two are more related? Crocodile/bird or crocodile/whale Human/dimetrodon or human/whale Which is the most primitive organism on this chart? 33 Identify Bird Z using the Dichotomous Key provided: Write your answer here: ______________________________________ S. Unicellular Organism Adaptations (PowerPoints A32 and A33) Explain how the following structures help unicellular organisms survive: • Important structures and their functions: Structure Contractile Vacuole Cilia and pseudopods Function Regulate ________________ content Movement and feeding ________________________ Movement Eyespot Detecting ________________ • • • • • • • • • 34 How do these adaptive behaviors help single-celled (unicellular) organisms survive in different habitats? • Chemotaxis - ____________________________________________________________________ • Phototaxis - _____________________________________________________________________ T. Plant and Animal Adaptations (PowerPoints A32, A34, A35, A36, A37, and A38) Plant Adaptations Non-Vascular (mosses, lichens, liverworts) Transport -Water through ____________________ - Nutrients through _________________ VS Vascular (Ferns, Grass, Herbs, Shrubs, Trees) ________________________(tissue) ___________________(food/glucose) Excretion and Respiration – Non-vascular plants excrete excess gases produced by cellular respiration and photosynthesis through ____________________, the movement of molecules from a high concentrated area to an area of low concentration. Mosses and algae excrete and take in oxygen and carbon dioxide with the environment through this process. Vascular plants excrete oxygen and waste through their _________________, but non-vascular plants lack vascular tissues, so they can't retain and deliver water to their other parts. They thrive in ___________________places and also _________________ water from an outside source. Like vascular plants, they release extra water to the atmosphere and its environment through ____________________. Non-vascular plants found in the _______________________, such as algae and seaweeds, excrete about _______-_______% of the oxygen in the atmosphere. The purpose for excreting these waste products is to help maintain __________________________ within the organism’s cells and tissues. All organisms must be able regulate _________, _______________(NaCl), and __________________(H2O). Vascular plants; however, have special microscopic openings on the surface of the leaves through where the diffusion takes place. These openings are called ____________________ and are formed by two adjacent ______________________ cells. Plants can also store waste in the ________________________ or in organs which are destined to fall off or die (ex. _____________________). Some plants excrete waste products into the soil, occasionally using the wastes as ______________________ weapons against other competing plants. 35 Nutrition – Plants absorb nutrients they need through their_______________ systems. However, in certain conditions or environments that have ______________________-______________ soils, some plants, called ____________________________ plants, get their nutrients from other organisms like insects, small reptiles, and rodents! A good example of this is the ___________________________________. • For life on land: – Vascular tissue- tube-like cells that transport water and nutrients from roots to leaves • Called xylem (for water) and phloem (for food) 36 – Roots- help anchor the plant to the ground and absorb water and nutrients from soil • – – Desert plants have shallow roots- quickly absorb rain Stems- support plant • hold up leaves for photosynthesis • hold up flowers to pollinators • transport water and food • can protect against predators Leaves- used for photosynthesis, control gas exchange and water loss • Rainforest floor- broad leaves • Desert- cactus have spines to prevent water loss • Cold climates- needles on evergreen trees 37 • For Reproduction: – Attracting pollinators- brightly colored or fragrant flowers – Seeds- protective coat outside, nourishment inside to protect plant embryo and allow it to lie dormant for awhile Kingdom: Archaea • Cell Structure: _________________________ (no nucleus) • Unicellular • They can make their own food by a process called ________________________________, or they can consume food. (autotroph/heterotroph) • Reproduction: asexual by _____________________ _____________________ • FYI: - Typically found in ______________________ environments – Thought to be the most _________________________ organisms on Earth Kingdom: Bacteria • Cell Structure: __________________________ (no nucleus) • Unicellular • ________________ (chemosynthesis & photosynthesis) or ________________ (recall fermentation) • Reproduction: mostly asexual by ______________ _________________, though some can reproduce sexually by ____________. • FYI: - Not all bacteria are harmful to humans – They come in many shapes – Used for _____________________________ Kingdom: Protists • Cell Structure: _______________________ (has nucleus) • Unicellular 38 • Autotrophic (_________________________) or heterotrophic • Reproduction: mostly asexual (________________ _____________________), but some sexual (_____________________________) • FYI: - Mostly found in ______________________ environments Kingdom: Fungi • Cell Structure: ______________________________ (has nucleus)- some have more than one! • Multicellular • Heterotrophic- they’re _______________________________ • Reproduction: asexual or sexual • FYI: - Some fungi can be harmful (Athlete’s foot, ringworm) – Others are useful: yeast, edible mushrooms Kingdom: Plants • Cell Structure: ______________________ (has nucleus) • Multicellular 39 • Autotrophic (______________________________) • Reproduction: mostly sexual • FYI: - Carnivorous plants are NOT heterotrophs, they can also do photosynthesis. – Self-pollination is NOT asexual reproduction Kingdom: Animals • Cell Structure: __________________________ (has nucleus) • Multicellular • Heterotrophic • Reproduction: mostly sexual • FYI:- Some animals can reproduce _____________________________ (regeneration, budding, fragmentation)- ex.: starfish Plants and animals have many structural adaptations- this is the reason we see so many different kinds of them. Recall an adaptation is any inherited _________________ that increases an organisms chance of survival. Annelid Worms (____________________ worms) 3 Classes: Oligochaetes- live in soil or freshwater Ex.: __________________________ Leeches- suck _____________________ and body fluids from host Polychaetes- live in ______________________ Ex.: sandworms, bloodworms Feeding methods: _________________ feeding, capture and eat, _____________________ o Earthworm digestion: __________________, __________________________, ________________ (stores food), _________________________ (grinds food), 40 ______________________ – food absorbed, _____________________ expelled through anus (________________________) Most reproduce ____________________; earthworms are _____________________ and can fertilize each other Earthworms are beneficial to _____________________ because they dig tunnels through the ground to allow beneficial ___________________ and ___________________ to penetrate. Insects - ________________________ (segmented body, _____________________, and jointed appendages) ______________________ (no vertebrae). • 3 body segments – ____________________ – with a pair of antennae and two eyes (usually __________________effective at detecting movement) – _______________________ – with ________ legs and usually _______ pairs of wings – ____________________________ – contains most of the insects organs • Contains small tubes that allow air to enter the body; oxygen then travels directly to the cells. • ______________________ – outer covering (made of ________________ and ______________) that supports and protects the body • Nutrition – various diets for different insects in different environments. • Plants/plant products • ___________________ (ex. fleas and mosquitoes) • ____________________ animal bodies (ex. ______________________ beetles) or animal waste (ex. _____________beetle) 41 Insect Life Cycles – 2 Types Incomplete (ex. ______________________) Egg _________________ adult Complete (ex. _______________________) Egg __________________(caterpillar) _____________________ (cocoon) ____________________ (butterfly) Amphibians ____________________________ (with a backbone) _________________________ (cold-blooded) Must absorb heat from _________________________ sources When environment becomes too hot or too cold, many amphibians become ________________________ (inactive or at rest) by burrowing in the ________________. All amphibians begin life in __________________ Most amphibian eggs are fertilized ______________________ Eggs do not have ____________________ (moist; must lay in water) 42 Fertilized eggs hatched into _____________________ (larval stage) Tadpoles have fins, ______________, and a ________-chambered heart Tadpoles develop into _______________. Develop legs, _______________, and a ___________-chambered heart Tadpoles obtain oxygen from ________________ that passes over gills Adults have ____________________ so that they can exchange ________________ with the air Adults also exchange gases through their thin, moist __________________. Mammals - ________________________ (backbone), have ________________, develop specialized ______________. • Have various glands, including ______________________________ glands that produce __________ • _________________________ (warm-blooded) • Can keep a ____________________ temperature by using energy from __________________. • ____________/____________ and fat also provide _____________________ from the environment. • Use _____________ to breathe • __________________________ (at bottom of ____________) forces air into and out of lungs • In lungs, ________________ enters blood and ____________________exits blood • ___-chambered heart and ___ loops of vessels – keeps oxygen-_____________ blood completely separate from oxygen-________________ blood • Blood also removes _________________ from cells and helps regulate body ____________________. • Movement- varies with organisms • ______________ on 2 or 4 limbs, ___________, ____________ on vines, use ______________ • Receives and interprets information from the _______________________________. • _______ senses: _____________, ______________, ____________, ____________, and ___________. • ____________________ and ___________________ signals travel to the ___________, and the brain directs the ______________ of the body • Reproduce ____________________ through internal _____________________ • Mammals are divided into _______-subclasses based on reproductive methods: • ___________________ mammals (90%) – give birth to young that have developed inside the mother’s _____________ until the body systems are fully developed. The _______________ is an organ that passes _______________________ and ____________________ to baby and removes ___________________ from baby through ____________________ _____________. • ____________________ – short period of development inside the mother’s body, then finishes development in a _________________. Ex.: ________________, kangaroo, koala 43 • ________________ – lay ____________. Only 3 (2 spiny anteaters and 1 duck-billed platypus) U. Animal Behavior (PowerPoint A39) Animal _______________ – an action or a group of actions performed by an animal in ______________ to some __________________. There are 3 types of animal behavior: 1. _____________ behavior – ___________________ determined behavior (animal is _________ with the ability to know how to do it) a. _______________ – simple, automatic response that involves no conscious control b. __________________ – complex innate behavior; ex.: __________________, nest building, web spinning c. _________________ – response made by the ____________ organism to an environmental stimulus - insects moving away from or toward light = ______________________ - moving toward chemical substance = ___________________ d. _____________________ – seasonal movement of animals, usually to a _________________ area e. _____________________ – a state of reduced ________________________ that occurs in animals living in conditions of intense ______________. f. _____________________ – a deep sleep in which body _______________, _______________ consumption, and ___________________ rate decrease (conserves ________________). 2. ___________________ behavior – obtained through practice or experience a. _______________________- occurs when an animal is repeatedly given a stimulus that is not associated with any ______________________ or ____________________ - horse not moving when cars go by on a road - Child keeps misbehaving when there is no punishment - Deer at Stone Mountain State Park (not camera-shy) 44 b. ________________________ – an animal forms a social attachment to an object during its “critical time” if you pick up a baby bird, it might think you are its mama c. _________________________________ (stimulus association)- animal learns to ________________ one event with another event EX: _____________________ dog experiments with ___________and _____________. d. ________________ and ______________ – keeps trying until the correct response is made; there must be a __________________. Mouse in a maze (gets faster each time); basketball 3. __________________ Behavior a. Communication within social structure using __________________________ (ex. Bees and ants) – Pheromone = a _____________________ released by an animal that ________________ the _____________________ or ___________________________ of other members of the same species through the sense of smell or taste – Ants leaving a trail to food, bees identifying and defending hive, attracting mates b. ______________________ __________________ – movements to attract _________________ Ex: Spiders, birds, humans c. _____________________________________ (ex. Fighting fish) – animal defends its __________________ space against other members of its species. Prevents _________________ and ____________________ survival. 45
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