Additional file 2
File Format: DOC
Title: Table of 91 genes identified using class comparison analysis.
Description: Genes differentially expressed between mild and moderate emphysema patients. “Y” indicates that the probes have been
represented in Affymetrix HG-U133A microarray chip.
Unique id
H200000301
H200000406
H200000512
H200000677
H200000945
H200000998
H200001000
H200001346
H200001438
H200001736
H200001865
H200001908
H200002010
H200002080
H200002156
H200002632
H200002708
H200002716
H200002784
Spira
set
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Mean
array
fold
change
1.46
1.27
1.29
0.79
0.76
1.39
0.63
0.67
0.75
1.36
0.50
0.66
1.32
0.80
1.24
0.77
0.75
0.69
0.79
Mean
TPCH
training
fold
change
1.70
1.26
1.41
*
0.95
1.37
1.19
1.44
1.11
1.14
*
1.25
1.22
1.14
1.00
1.46
Mean TPCH
independent
set fold
change
4.28
4.83
2.84
1.33
Array
Parametric
p-value
0.0022
0.0071
0.0091
0.0084
0.0025
0.0026
0.0023
0.0009
0.0053
0.0038
0.0099
0.00002
0.0075
0.0063
0.0074
0.0018
0.0015
0.0052
0.0088
TPCH
training
pvalue
0.0318
0.0252
0.0386
TPCH
independent
set p- value
0.0099
0.2142
0.0646
0.7881
0.0218
0.5769
0.4437
0.1160
0.9819
GeneBank
accession
NM_000077
D42055
NM_000849
NM_000226
NM_001220
NM_017953
NM_006903
NM_006747
AF136407
NM_001545
AK057328
NM_018203
U79297
AF121858
AK054689
D86964
NM_005558
NM_012093
AB037725
Gene symbol
CDKN2A
NEDD4
GSTM3
KRT9
CAMK2B
ZNHIT6
SID6-306
SIPA1
C6orf5
ICT1
FLJ10748
SNX8
DOCK2
LAD1
AK5
SRGAP1
Unique id
H200002856
H200003203
H200003282
H200003420
H200003440
H200003537
H200003640
H200004155
H200004928
H200005125
H200005339
H200005357
H200005448
H200005581
H200006290
H200006635
H200006810
H200007262
H200007273
H200007497
H200007517
H200007642
H200007690
H200007838
H200007867
H200008070
H200008154
H200008156
H200008288
H200008433
H200008505
Spira
set
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Mean
array
fold
change
0.66
0.56
1.43
1.29
1.38
0.75
0.76
0.73
1.36
0.54
0.64
0.77
1.26
1.30
1.64
1.42
1.44
1.33
1.26
1.47
0.81
1.26
0.76
1.32
1.44
1.40
1.24
1.26
0.75
0.75
0.66
Mean
TPCH
training
fold
change
Mean TPCH
independent
set fold
change
1.02
1.22
1.37
*
0.99
1.15
1.05
1.16
0.98
1.15
7.53
2.05
1.79
1.16
0.39
1.14
2.90
1.06
1.16
1.30
0.84
1.54
1.01
1.06
1.65
2.50
Array
Parametric
p-value
0.0003
0.0001
0.0019
0.0082
0.0010
0.0051
0.0067
0.0044
0.0090
0.0089
0.0003
0.0093
0.0041
0.0087
0.0049
0.0098
0.0016
0.0008
0.0031
0.0013
0.0086
0.0100
0.0017
0.0051
0.0021
0.0031
0.0099
0.0051
0.0043
0.0055
0.00003
TPCH
training
pvalue
TPCH
independent
set p- value
0.1024
0.9492
0.6990
0.9236
0.1839
0.0194
0.0224
0.0140
0.4523
0.7471
0.0867
0.3266
0.2526
0.0323
0.9382
0.1203
GeneBank
accession
NM_030793
NM_005700
NM_018842
NM_022136
AK056630
NM_001330
NM_017782
NM_033317
NM_003136
NM_054023
NM_013352
NM_014037
NM_012334
AF339776
NM_000300
NM_001796
NM_004369
L22650
BC011630
AB037804
NM_014908
NM_015640
AK025893
AB051548
NM_003318
NM_002183
NM_002615
NM_014904
AK057131
NM_017512
NM_004306
Gene symbol
SP329
DPP3
LOC55971
SAMSN1
CTF1
FLJ20360
ZD52F10
SRP54
SART-2
NTT5
MYO10
PLA2G2A
CDH8
COL6A3
EPAG
KIAA1383
KIAA1094
PAI-RBP1
FLJ14743
TTK
IL3RA
SERPINF1
Rab11-FIP2
HSRTSBETA
ANXA13
Unique id
H200008939
H200008958
H200008994
H200009299
H200009441
H200010090
H200010806
H200011062
H200011229
H200011233
H200011369
H200011944
H200012231
H200012824
H200013205
H200013655
H200014078
H200014189
H200014801
H200015239
H200015337
H200015361
H200015466
H200015598
H200016125
H200016317
H200016589
H200016590
H200016675
H200017180
H200017197
Spira
set
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Mean
array
fold
change
1.37
1.46
1.58
0.60
0.77
1.32
1.27
0.77
1.32
1.34
1.33
1.33
1.28
0.81
1.30
0.80
0.79
0.76
1.24
1.34
1.26
0.81
0.75
0.78
1.26
0.74
1.43
0.78
1.28
0.80
1.55
Mean
TPCH
training
fold
change
0.60
0.87
1.11
1.35
1.13
1.01
Mean TPCH
independent
set fold
change
1.38
1.44
*
*
*
0.78
0.93
1.21
1.13
Array
Parametric
p-value
0.0022
0.0090
0.0098
0.0001
0.0034
0.0002
0.0038
0.0081
0.0008
0.0088
0.0083
0.0002
0.0092
0.0069
0.0088
0.0085
0.0031
0.0077
0.0084
0.0026
0.0060
0.0098
0.0066
0.0048
0.0099
0.0006
0.00001
0.0023
0.0064
0.0073
0.0031
TPCH
training
pvalue
TPCH
independent
set p- value
0.0073
0.4056
0.1548
0.0385
0.3644
0.0251
0.6033
0.2468
0.3385
GeneBank
accession
AK021603
AK021793
AK022258
NM_002644
NM_020672
AF084555
AK057432
AB067467
AK024978
NM_016588
NM_005264
NM_002618
AL117477
NM_024762
AL137315
AF119843
NM_005339
NM_000200
NM_021105
NM_032365
AL109681
U50748
NM_017928
AK022114
X57131
NM_002999
AB037830
NM_016569
BC014124
AL157439
NM_005525
Gene symbol
PIGR
LOC57402
ARPP-19
KIAA1880
LSR68
LOC51299
GFRA1
PEX13
DKFZP727G051
FLJ21603
PPP4R1L
HIP2
HTN3
PLSCR1
MGC5254
LEPR
FLJ20694
H2AFFP
SDC4
KIAA1409
TBX3
HSD11B1
Unique id
H200017277
H200018561
H200018762
H200018789
H200018824
H200019126
H200019211
H200019309
H200019452
H200019497
H200019564
H200019565
H200020785
H200020805
H200020945
H200021147
H200021295
Spira
set
Y
Mean
array
fold
change
0.71
1.31
1.27
1.31
0.79
1.29
1.34
1.27
1.28
1.38
1.37
0.81
1.27
1.52
0.79
1.28
0.80
Mean
TPCH
training
fold
change
*
Mean TPCH
independent
set fold
change
Array
Parametric
p-value
TPCH
training
pvalue
TPCH
independent
set p- value
0.0031
0.0005
0.0036
0.0074
0.0074
0.0057
0.0078
0.0029
0.0087
0.0045
0.0061
0.0079
0.0085
0.0088
0.0097
0.0021
0.0044
*Probes that blasted partly or fully to multiple gene sequences, **DNA sequences difficult to design primers and /or optimize
GeneBank
accession
NM_000500
AK025148
NM_032135
U79276
AK001567
AK054633
AF339828
NM_032546
AK023292
AK025983
NM_033062
BC017742
AK056398
AK056109
AK054715
AK057241
BC017706
Gene symbol
CYP21A2
DKFZP434F1017
IMAGE3451454
RNF30
KAP4.2