TP53 alterations in acute myeloid leukemia with complex
karyotype correlate with specific copy number alterations,
monosomal karyotype, and dismal outcome
by Frank G. Rücker, Richard F. Schlenk, Lars Bullinger, Sabine Kayser, Veronica
Teleanu, Helena Kett, Marianne Habdank, Carla-Maria Kugler, Karlheinz Holzmann,
Verena I. Gaidzik, Peter Paschka, Gerhard Held, Marie von Lilienfeld-Toal, Michael
Lübbert, Stefan Fröhling, Thorsten Zenz, Jürgen Krauter, Brigitte Schlegelberger,
Arnold Ganser, Peter Lichter, Konstanze Döhner, and Hartmut Döhner
Blood
Volume 119(9):2114-2121
March 1, 2012
©2012 by American Society of Hematology
Mapping of 168 TP53 mutations in 141 CK-AMLs.
Frank G. Rücker et al. Blood 2012;119:2114-2121
©2012 by American Society of Hematology
Relative frequencies and pairwise co-occurrences of TP53 alteration-associated genomic
aberrations illustrated using Circos Table Viewer Version 0.52.28 The percentages indicate the
proportion of each aberration associated with (A) TP53altered CK-AMLs and (...
Frank G. Rücker et al. Blood 2012;119:2114-2121
©2012 by American Society of Hematology
Kaplan-Meier survival estimates according to the TP53 status.
Frank G. Rücker et al. Blood 2012;119:2114-2121
©2012 by American Society of Hematology
Kaplan-Meier survival estimates according to the cytogenetic status.
Frank G. Rücker et al. Blood 2012;119:2114-2121
©2012 by American Society of Hematology