Province of Limburg Life Sciences & Health in Limburg Province of Limburg Index The Life Sciences & Health sector in Limburg What do we offer you? Contact us for more information • • • • • • • • • • • An introduction Facts & figures The Life Sciences & Health landscape Brightlands Maastricht Health Campus Why Limburg? Who is here? Education Testimonial LIOF is your partner Contact Associations & networks Province of Limburg The Life Sciences & Health sector in Limburg – An introduction Strong Life Sciences cluster The Province of Limburg and adjacent border region (Germany and Belgium) represent a strong Life Sciences cluster with core competences in biotechnology, cardiovascular research and molecular imaging and biomaterials. For life sciences companies the place to be is Brightlands Maastricht Health Campus in Maastricht. It houses a unique line of advanced imaging instruments for MRI, electron microscopy and mass spectrometry relevant for tracking molecular, cell, tissue and in-organ or body processes Research and clinical care focus Research and clinical care focus is on the brain and neurological system, the heart muscle and vascular system, orthopaedics and spine, and ophthalmology. Underlying health management methodology concentrates on healthy living, pre- and early diagnosis, minimally invasive technologies and regenerative medicine applications Logistics distribution hotspot The Limburg region is situated where the Netherlands, Germany and Belgium intersect. In 15-mile radius there are four university hospitals (in Maastricht, Liège and Aachen). This unique feature has proven to be an advantage for ‘Euregional’ clinical projects and product introduction & distribution in the large German market nearby. For that reason Limburg has become the European distribution hotspot for the international medical device industry (Medtronic, Boston Scientific, Abbott, Stryker, to name just a few) Province of Limburg The Life Sciences & Health sector in Limburg – Facts & figures Companies already established in Limburg: no. of companies 300 no. of jobs 94,400 contribution to total employment in the Limburg region 18.30 % 130 world-class research centres and groups in life sciences no. of students on Brightlands Health Campus 300 innovative companies in medical technology and biotechnology 4,000 no. of life sciences students 5 top universities and 3 university hospitals within a 15-mile radius of Maastricht 17,000 life sciences students and 11,000 university employees 17,000 Province of Limburg The LSH sector in Limburg – Brightlands Maastricht Health Campus Brightlands Chemelot Campus Performance materials Bio-based materials Biomedical materials Sustainable technologies Venlo Brightlands Smart Services Campus Big data analysis Finance & business Brightlands Maastricht Health Campus Sittard-Geleen Maastricht Heerlen Regenerative medicine Cardiovascular medicine Biomedical imaging Brightlands Campus Greenport Venlo Food Nutrition Health Province of Limburg The LSH sector in Limburg – Brightlands Maastricht Health Campus Brightlands Maastricht Health Campus and Maastricht University Medical Centre (MUMC+) Maastricht Health Campus & the Brightlands framework Maastricht Health Campus has a strong focus on diagnostics and biomaterials. This is facilitated by a unique collaboration within the Brightlands framework with Chemelot Materials Science Campus. Outcome: new biomaterials and biocompatible coatings for medical use (implants, medication, cell growth and commercial culturing) in conjunction with the development of appropriate manufacturing technologies, with pre-clinical and clinical work carried out at the University Medical Centre Focus on: • Prevention, treatment and research on heart diseases and the vascular system • Regenerative medicine: cell therapy, tissue engineering, bio-based materials with applications in cardiac, orthopaedic & spine, and ophthalmology. • Precision imaging: from nano to macro (nanoscopy, mass spectrometry, high-resolution imaging); from research to ground-breaking clinical applications (Iknife) Unique imaging infrastructure The presence of three ultra high-field whole-body clinical MRI scanners: a 3T Prisma, an actively-shielded 7T system, and one of only five 9.4T systems in the world, complemented by high-power electron microscopy and advanced mass spectrometry Province of Limburg The LSH sector in Limburg – Brightlands Maastricht Health Campus The Heart-Vessel Center The Heart-Vessel Centre (hospital department and research school) has expertise in prevention, treatment and research on patients suffering from heart and other cardiovascular problems. Its main areas of expertise are: • Cardiology • Heart surgery • Vessel surgery • Phlebology • Internal vascular medicine • Vascular neurology Clinical practice facility (for industry and medical clinical training) International medical teaching environment in which doctors and other professionals in health care can increase their cardiovascular knowledge and skills in accordance with the latest developments in technology and science Province of Limburg The LSH sector in Limburg – Brightlands Maastricht Health Campus Medical centres Knowledge institutions • • • • Maastricht University Medical Centre MAASTRO Clinic (cancer radiology treatment) • • CARIM: medical school for cardiovascular diseases MERLN: institute for technology-inspired regenerative medicine Brains Unlimited: neurological institute Centre for Integrated Healthcare: centre for medical and psychological care Province of Limburg The LSH sector in Limburg – Brightlands Maastricht Health Campus Ranks 14th in the Times Higher Education top 100 ‘most international universities in the world’ Maastricht University Medical Center Europe's largest integrated academic center. 44th in the Times Higher Education rankings for clinical, preclinical and health care Medtronic is one of the world’s leaders in the medical devices industry. The Medtronic Bakken Research Centre, with approximately 300 employees, is located at Brightlands Maastricht Health Campus, from where it coordinates its European research and clinical programmes This organization’s multinational research centre for medical and pharmaceutical products is located at Brightlands Maastricht Health Campus Province of Limburg What do we offer you? Province of Limburg LSH sector – Why Limburg? Access to the best clinical research The Clinical Trial Centre Maastricht is the leading academic clinical research organization of the Netherlands. • • • • 100 employees, involved in 450 studies per year €4.5 million turnover Maastricht University Hospital is the only shareholder and largest customer Some other customers: Pfizer, Quintiles, ECRIN, BioActor, VitaK, Zuyderland, VieCuri and many smaller start-ups and SMEs • Customer satisfaction: 8.2 out of 10 Province of Limburg LSH sector – Why Limburg? Access to the best clinical research The Netherlands has one of the best-documented populations in the world. String of Pearls Initiative: bio-bank infrastructure (largest in the EU) linking all university medical centres gathering clinical data and biomaterials for nine different disease areas, ‘pearls’ The Maastricht Study: unique 10 k cohort phenotyping study on type 2 diabetes and its customary complications, including cardiovascular disease Special advantage of Limburg: access to three university hospitals (Maastricht, Aachen, Liège) in three countries (NL, DU, B) within 30 minutes Province of Limburg LSH sector – Why Limburg? Access to state-of-the-art facilities Laboratories Clean rooms Large cohorts Scanners: 3, 7 & 9 Tesla MRI, pet scanners Incubators Business parks Province of Limburg LSH sector – Why Limburg? Access to state-of-the-art facilities for MRI imaging Access to state-of-the-art facilities for bio-imaging M4I: basic, instrumentation and applied studies in molecular imaging. High-resolution imaging of biological surfaces; mass spectrometry & nanoscopy. MI instrumentation centre unique in Europe • • • 3T – a multi-purpose system for many kinds of clinical applications 7T – on the edge of clinical utility, developing the next wave of scientific breakthroughs 9.4T – a unique system providing unparalleled insights into the workings of the brain and the body Province of Limburg LSH sector – Why Limburg? Access to world-class medical equipment builders Have access to state of the art facilities for BIO imaging • M4I : fundamental, instrumentation and applied studies in molecular imaging. High resolution imaging of biological surfaces; mass spectrometry & nanoscopy. Unique MI instrumentation centre in Europe. • • EU customers like Biotronik, MEKO and Boston Scientific working with the NSI-7 Spin-offs to US customers: Boston Scientific, Abbott, Cordis, etc. 100% inspection of stents: geometry, surface and wall thickness Province of Limburg LSH sector – Why Limburg? Access to world-class medical equipment builders Province of Limburg LSH sector – Why Limburg? Access to world-class medical equipment builders Medical quality system • ISO 9001:2008 • ISO 13485:2012 AC2012 Advanced Instruments Manufacturing B.V. (AIM B.V.) The only Dutch FDA-registered contract manufacturer with more than 40 years of experience in medical devices production and life cycle management. In compliance with • 21CFR820 (USA) • CMDCAS (Canada) • MLHW Ministerial Ordinance No. 169, 2004 (Japan) Equipment qualifications • UL and CE certified equipment Equipment production, e.g. • EEG • ECG • Continuous blood pressure • Ultra Sound • High-frequency equipment • Hypothermia • Physiotherapy • Laboratory equipment Province of Limburg LSH sector – Why Limburg? Access to world-class medical equipment builders • • • • Connecting devices to patients and transferring their bio-electric signals Disposable and reusable electrodes, like EMG needles, multiple electrode patches and nerve stimulation probes HQ in the Netherlands, production facility in Asia, service hub in USA (Minnesota) Turn-key development and manufacturing, including all regulatory activities (eg. CE / 510k) Province of Limburg Why Limburg? – Showcase Medtronic / Bakken Research Bakken Research Maastricht • Most of its 300 employees are engaged in designing and managing clinical studies and in generating data for regulatory and reimbursement dossiers in Europe, Japan and the USA • About 30 scientists, engineers and technicians work closely with medical innovators in mainly European hospitals and universities to develop, build and study new devices or methods • Close to 50 linguistic specialists manage the translation of Medtronic’s product manuals and the texts on our product display screens • 25 quality and regulatory affairs professionals ensure that our products and services meet or exceed all applicable requirements Province of Limburg LSH sector – Who is here Province of Limburg Education in Life Sciences & Health Education Type of education Focus areas Maastricht University/ University Hospital University Biomedical sciences, European public health, health sciences, medicine, neuroscience, research, epidemiology, health food innovation management, and more Zuyd University University of Applied Science Care and technology, midwifery, health care Fontys Limburg University of Applied Science Pedagogy Gilde Opleidingen Vocational education Assisting in health care, nursery Arcus College Vocational education Pharmaceutical and physician assistant, technical care, nursery ROC Leeuwenborg Vocational education Pedagogy, nursery Province of Limburg LSH sector – Testimonial ‘In Europe we are number one in the surgical treatment of extensive aneurysms, in volume and complexity. And the annual European Vascular Course event in Maastricht is the meeting place for sharing related best clinical practices among vascular surgeons and the medical industry.’ Maastricht UMC+ and Uniklinik RWTH Aachen Province of Limburg LIOF is your partner We are your partner for making a successful start in the region: • • • • • • Advice on setting up your business and finding the best location Use our extensive local & national network Information on business climate Go on a Fact Finding Tour As your guide, LIOF Assistance in finding skilled personnel ensures that your Information about the region: Quality of Life company finds the best location in Limburg: from here you will succeed in achieving your European expansion! Province of Limburg Contact us for more information Limburg Development and Investment Company Maastricht Office Boschstraat 76 6201 BH Maastricht The Netherlands Innovatoren 3n Sint Jansweg 15 5928 RC Venlo The Netherlands Venlo Office Contact person: Sjoerd Boomsma Foreign Investment Development Logistics [email protected] +31 6 54 64 06 45 www.liof.com Province of Limburg The LSH sector – Associations & networks Relevant Limburg-based associations and network organizations active in the Life Sciences and Health sector Association Goal URL LifeTecZone Networking www.lifeteczone.nl/ Brightlands Brightlands hosts four campuses in Limburg that focus on research and business in materials, food, smart services and health. Brightlands offers accommodation, business and talent support, and a community focused on innovation in a global context www.brightlands.com/
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