You are welcome to the Seminar in Statistics! Date: 9 May 2017 (Tuesday) Time: 13:00 – 15:00 Place: K1073 Lecturer: Krzysztof Podgórski (Lund University) Title: Statistics at random events -- theory and applications Abstract: The talk intends to provide general introduction to a method of analyzing statistical distributions of variables observed at random events of a stochastic process or field. The methodology is aiming at very practical problems and its applicability will be shown on several examples. Nevertheless, it also roots in some purely mathematical considerations going back to the Banach Indicatrix theorem (1925) that later has been generalized in multidimensional formulation through the area-coarea theorem in geometrical measure theory. Our approach draws also on Kac (1943) and Rice's (1944-45) results on the average number of zeros of a random signal. After motivation and a survey of historical aspects of the theory, we turn to the generalized Rice formula approach to deriving long-run distributions of characteristics defined at random events of a stochastic process or field. We illustrate it through a number of practical contexts in which the methodology proves to be useful. In particular, we show applications to sea surface dynamical models and analyses of stochastic vehicle responses. Short break Page 2 (2) Lecturer: Josef Wilzén (Linköping University) Title: Physiological Gaussian Process Priors for the Hemodynamics in fMRI Analysis (Jointly with Anders Eklund and Mattias Villani). Abstract: Inference from fMRI data faces the challenge that the hemodynamic system that relates the underlying neural activity to the observed BOLD fMRI signal is not known. We propose a new Bayesian model for task fMRI data with the following features: (i) joint estimation of brain activity and the underlying hemodynamics, (ii) the hemodynamics is modeled nonparametrically with a Gaussian process (GP) prior with physiological information and (iii) predicted BOLD is not necessarily a linear time-invariant (LTI) system. We place a GP prior directly on the predicted BOLD time series, rather than on the hemodynamic response function as in previous literature. This allows us to incorporate physiological information via the GP prior mean in a flexible way. The prior mean function may be a standard LTI system based on a canonical hemodynamic response function, or a more elaborate physiological model such as the Balloon model. This gives us the nonparametric flexibility of the GP, but allows the posterior to fall back on the physiologically based prior when the data are weak. Results on simulated data show that even if we use an erroneous prior for the GP, the proposed model is still able to discriminate between active and non-active voxels in a satisfactory way and is able to discover the true functional form of the underlying hemodynamics. The proposed model is applied to real fMRI data, where our Gaussian process model finds activity where a baseline model with fixed hemodynamics does not. The learned hemodynamics show a time varying behavior, that can not easily be captured with by an LTI system, even when the hemodynamic response function is estimated. Lecturer: Anders Hildeman (Chalmers University of Technology) Title: Bayesian level set methods for point process data. Abstract: The level set method is a popular approach to inverse problems where interfaces between regions of differing properties are to be identified. Recent research has reformulated such problems in to a Bayesian context where regularization is introduced by the choice of priors. We develop this approach for point process data in spatial statistics. The observed data is assumed to be a point pattern over a spatial domain consisting of several regions with fundamentally different point pattern behavior, and where the classification of the spatial domain in to these regions is unknown. The aim of the analyst might be either to classify the regions, perform Kriging predictions or derive some field parameter properties from one or several of the point pattern classes. The proposed level set method can be viewed as an extension to the log-Gaussian Cox process model, where the latent Gaussian random field is replaced by a latent level set mixture of Gaussian fields.
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