CMS UPDATES: Observation and the 2-Midnight Rule Society of Cardiovascular Patient Care 18th Congress – San Antonio, Texas Michael A. Ross MD FACEP Professor of Emergency Medicine Emory University School of Medicine Medical Director – Observation Medicine Atlanta, Georgia Disclosure of Commercial Relationships: • Nature of Relationship Name of Commercial Entity • • • • • • • Advisory Board Consultant Employee Board Member Shareholder Speaker’s Bureau Patents • Other Relationships ` None None None None None None None CMS Technical Advisory Panel: AMI, HF, pneumonia Past CMS APC Advisory Panelist Chair – Visits and Observation Subcommittee Co-chair, Mission Lifeline Atlanta, AHA Objectives: • A. Past: Understand the background and history of observation services and the 2-Midnight Rule • B. Present: Know the “Two Midnight Rule” and how it relates to observation medicine • C. Future: Know current and future CMS policy issues regarding Observation Services and the 2-Midnight Rule The Anatomy and Physiology of Medicare . . . • U.S. Government: • Senate • House of Representatives • Executive Branch • Cabinets • Secretary of State, etc • Secretary of Health and Human Services Emory University 4 • Judicial Branch • Legislative Branch: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. Assistant Secretary for Health Public Health Service Office of the Surgeon General Public Health Service Commissioned Corps Assistant Secretary for Preparedness and Response Office of the Assistant Secretary for Preparedness and Response Biomedical Advanced Research and Development Authority Assistant Secretary for Legislation Assistant Secretary for Planning and Evaluation Assistant Secretary for Administration Assistant Secretary for Public Affairs Assistant Secretary for Financial Resources Office of the Inspector General Administration for Children and Families Administration on Aging Agency for Healthcare Research and Quality Agency for Toxic Substances and Disease Registry Centers for Disease Control and Prevention Centers for Medicare and Medicaid Services Food and Drug Administration Health Resources and Services Administration Indian Health Service National Institutes of Health Substance Abuse and Mental Health Services Administration Emory University 5 DHHS: Center for Medicare and Medicaid Services • Employs approximately 4,100 employees: • Hubert H. Humphrey Building in Washington, D.C. • 10 regional offices • Various field offices located throughout the United States. • The head of the CMS is appointed by the president and confirmed by the Senate. Emory University 6 • 2,700 are located at its headquarters in Baltimore • The remaining employees are located in: Regional Offices • Region I – Boston, Massachusetts • Connecticut, Massachusetts, Maine, New Hampshire, Rhode Island and Vermont. • Region II – New York City, New York • New Jersey, New York, as well as the U.S. Virgin Islands and Puerto Rico. • Region III – Philadelphia, Pennsylvania • Delaware, Maryland, Pennsylvania, Virginia, West Virginia and the District of Columbia. • Region IV – Atlanta, Georgia • Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina and Tennessee. • Region V – Chicago, Illinois • Illinois, Indiana, Michigan, Minnesota, Ohio and Wisconsin. • Region VI – Dallas, Texas • Arkansas, Louisiana, New Mexico, Oklahoma and Texas. • Region VII – Kansas City, Missouri • Iowa, Kansas, Missouri, and Nebraska. • Region VIII – Denver, Colorado • Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming. • Region IX – San Francisco, California • Arizona, California, Hawaii, Nevada, the Territories of American Samoa, Guam, and the Commonwealth of the Northern Mariana Islands. • Region X – Seattle, Washington • Alaska, Idaho, Oregon, and Washington 1. 2. 3. 4. 5. Medicare Medicaid State Children’s Health Insurance Program (SCHIP) Clinical Laboratory Improvement Amendments (CLIA) Health Insurance Portability and Accountability Act (HIPA) of 1996 Note: Medicare eligibility is determined by the Social Security Administration Emory University 8 Medicare administers: • • • • Part A: Hospital Insurance - 1966 Part B: Medical Insurance Part C: Medicare Advantage plans Part D: Prescription drug plans Emory University 9 Medicare Parts Part A: Hospital Insurance • Part A covers inpatient hospital stays, including semiprivate room, food, and tests. • Part A — For each benefit period, a beneficiary will pay: How much??? Emory University 10 • Definition of an inpatient – to be discussed Part A: Hospital Insurance • Part A covers inpatient hospital stays, including semiprivate room, food, and tests. • Part A — For each benefit period, a beneficiary will pay: • A Part A deductible of $1,216 (in 2014) for a hospital stay of 1–60 days. • A $304 per day co-pay (in 2014) for days 61–90 of a hospital stay. • A $592 per day co-pay (in 2014) for days 91–150 of a hospital stay, as part of their limited Lifetime Reserve Days. • All costs for each day beyond 150 days[33] • Coinsurance for a Skilled Nursing Facility is $144.50 per day (in 2012) for days 21 through 100 for each benefit period. • A blood deductible of the first 3 pints of blood needed in a calendar year, unless replaced. There is a 3 pint blood deductible for both Part A and Part B, and these separate deductibles do not overlap. • Covers hospice benefits Emory University 11 • Definition of an inpatient – to be discussed Part A: Rehab or Skilled Nursing Facility (SNF) payment 1. A preceding hospital stay must be at least three days as an inpatient, three midnights, not counting the discharge date. 2. The nursing home stay must be for something diagnosed during the hospital stay or for the main cause of hospital stay. 3. If the patient is not receiving rehabilitation but has some other ailment that requires skilled nursing supervision then the nursing home stay would be covered. 4. The care being rendered by the nursing home must be skilled. • Medicare part A does not pay stays which only provide custodial, nonskilled, or long-term care activities, including activities of daily living (ADL) such as personal hygiene, cooking, cleaning, etc. Emory University 12 • The Four “IF”s: • Medicare will take back hospital inpatient payments and far more, 4 to 18 times the initial payment, if an above-average number of patients from the hospital are readmitted within 30 days. • These readmission penalties apply after some of the most common treatments: pneumonia, heart failure, heart attack, COPD, knee replacement, hip replacement Emory University 13 Hospital Inpatient Readmission Penalties . . . Medicare Contractors • MAC: Medicare Administrative Contractors • RAC: Recovery Audit Contractors 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. Outpatient hospital procedures and visits Physician and nursing services X-rays Laboratory and diagnostic tests Influenza and pneumonia vaccinations Blood transfusions Renal dialysis Limited ambulance transportation Immunosuppressive drugs for organ transplant recipients Chemotherapy Hormonal treatments such as lupron Other outpatient medical treatments administered in a doctor's office. 13. Medication administered by the physician during an office visit 14. Durable Medical Equipment Emory University 15 Medicare Part B coverage includes: Medicare Part B - deductible • Exceptions – Medicare pays: • Most lab services – 100% • Outpatient mental health services – 55% (planned trending toward 20% over several years) Emory University 16 • For “covered” services - After a beneficiary meets the yearly deductible of $140.00, they will be required to pay a coinsurance of 20% Medicare payment issues: Inpatient vs. Outpatient Outpatient: ED or Obs • 20% copayment for all unpackaged services • Time does NOT count toward SNF • Self administered drugs NOT covered Inpatient • Single copayment for MSDRG ($1,216) • Time counts toward 3-day SNF benefit • Self administered drugs included Where to find Medicare Part B coverage criteria: • National Coverage Determinations (NCD) • at the national level • multi-state area managed by a specific regional Medicare Part B contractor • Other sources: • • • • CMS Internet-Only Manuals (IOM) The Code of Federal Regulations (CFR) The Social Security Act The Federal Register Emory University 18 • Local Coverage Determinations (LCD) Medicare rule making process: • Proposed Rule (Federal Register) • Open comment period • Public / stakeholder organizations • HOP (Hospital Outpatient Panel) • Med Pac • Closed comment period • Final Rule (Federal Register) • Program Memorandum • Hospital Manual • CMS website • Implementation date The 2-MN Rule: How did we get here??? 1983: DRGs “Houston, we have a problem”. . . • The Problem: • Patients that are “too sick to go home, but do not meet inpatient admission criteria” • The Solution: CMS created a “fix”: • Observation Services 20 DEFINITION: OBSERVATION Observation services are those services furnished on a hospital's premises, including use of a bed and periodic monitoring by nursing or other staff, which are reasonable and necessary to evaluate an outpatient's condition or determine the need for a possible admission as an inpatient... ... Such services are covered only when provided by order of a physician or another individual authorized by State licensure law and hospital bylaws to admit patients to the hospital or to order outpatient tests. . . . . . Observation services usually do not exceed one day. Some patients, however, may require a second day of outpatient observation services. Observation services exceeding 48 hours will be denied. Observation services history: as the Pendulum swings. . . • 1984 – The creation of observation services (unstructured) • Pendulum swings to observation • Hospitals over-use for all outpatient surgeries • Pendulum swings to admission • 2003 – CMS starts paying observation for only 3 conditions with many stipulations • Slight rise in obs • 2007 – CMS removes stipulations, starts paying for all obs conditions, interqual grows, RAC and readmission penalties grow • Pendulum swings to observation • 2012 – CMS redefines inpatient: the 2-MN rule • Decrease prolonged observation and RAC audits? • Impact on observation services? Emory University 22 • 2000 – CMS stopped paying separately for observation CMS Payment Policy for Observation Services - APC 8009 (effective 2014) • Requirements: • Physician order and documentation supporting the need for observation • Preceding (packaged) HOSPITAL visit: any of the following • • • • Clinic visit (HCPCS code G0463) Type A ED visit - level 4 or 5 (HCPCS code 99284; 99285) Type B ED visit – level 5 (HCPCS code G0384) Critical care (CPT code 99291) • Minimum of 8 hours of observation: • “observation services of substantial duration” • HCPCS code G0378 X 8 or more • No associated “T-status” procedure on the same or preceding day • Surgery or procedures • 2014 APC 8009 Payment Amount = $1,357 • 2014 APC 99285 amount = $ 456 Growth in observation services • 2007 – 2009: Observation Services • 34% rise in Medicare ratio of observation to inpatient stays (Feng, Health Affairs, 2012; 31:6 1251-1259) Reasons for growth in OS: 1. Return to baseline – observation policy changes • 2000 - OS Elimination • 2003 - 3 conditions with restrictions • 2007 - No restrictions, all conditions 2. 3. 4. 5. Shift from inpatient to outpatient – independent of OS RAC audit pressures – 80% targeted status issues Re-admission pressures – stiff penalties Admission criteria confusion • CMS criteria – legally binding, simple, intuitive (not used) • RAC criteria – often commercial criteria (i.e. Interqual) • Issues – a “book”, complex, poor evidence basis for several conditions (musculoskeletal pain in the elderly) Trends in observation services • 2007 – 2009: length of stay creep (Feng, Health Affairs, 2012; 31:6 1251-1259) • >24 hours = 50% • >48 hours = 10% Reasons for LOS creep . . . • Patient selection: A growing pool of patients that did not meet Interqual criteria • Hospital fears – RAC and readmissions • Setting – type 4 setting B. The Present: OIG Reports • Driven by concerns: To clarify • Use of observation, long outpatient, and short inpatient services • Copayments for OS vs DRG • Impact of these services on SNF benefit • Issues with 2-midnight rule • Scope of improper payments for all the above 2012 Medicare Data: OBS, LOPS, and SIPS • OBS: Observation volumes - 2.1 million: • 1.5 million Obs => home • 0.6 million Obs => Inpatient • 78% began in the ED; 9% from cath lab/OR • LOPS: Non-observation outpatient volumes: • 1.4 million Long OP stays • SIPS: Short Inpatient Stays ( <2 nights) • 1.1 million SIPs • Case mix was similar across all three groups! • Total = 4.6 million claims Does observation cost Medicare less? YES!!! – almost 3 times less • Over all: • SIPS = $5.9 BILLION • Obs = $2.6 BILLION • By case: • SIPS = $5,142 per case • Obs = $1,741 per case • Variation between conditions, however all favor observation over inpatient Does observation cost patients more? NO!!! • Average inpatient copay is almost twice as much as obs • Observation copay is less than inpatient 94% of the time • Average SIPS copayment = $725 • Average Obs copayment = $401 • 51% had self admin Rx costs = $528 • 6% (n=84K) paid more than IP deductible • 0.2% (n=3K) paid more than 2X IP deductible • By condition: • IP more for 12/14 (359-$572 more) • IP less for 2/14: Stent ($817) and circulatory disorder ($359) • Policy question: • Do you compromise the 94% for the 6%? • How to address the copayment issue? SNF Breakdown: • 3 days, but less than 3 IP days • Received SNF services • Medicare paid (inappropriately) = 617,702 = 25,245 (4%) = 23,148 (92%) • Medicare payment = $255M • Ave patient copay = $2,735 • Medicare did NOT pay • Ave patient copay = 2,097 (8%) = $10,503 • Bottom Line: • SNF patients at risk represent 0.6% of whole group IS THIS REALLY TRUE???? • 100% of 2009 Medicare inpatient and outpatient claims: • >1 million observation visits • 2.9% (29,324) discharged to a SNF • 62% came from the SNF • 8% came from a NH • 26% (7,537) came from community (at risk) • 0.75% (7,537) with SNF benefit at risk • NOTE: OIG (above) reported that CMS still paid 92% of these (inappropriately). Is observation hiding readmissions? - NO For all Medicare beneficiaries: 2007-2012 • IP admits/ben fell 4.3% • IP re-admits/ben fell 6.8% • Obs visits/ben increased 11% • Obs “re-admits”/ben increase 3.7% • In absolute numbers: • Observation did not come close to accounting for the decline in readmissions Is observation hiding readmissions? - NO Pressure on CMS to do something B. PRESENT: IPPS 2 Midnight Rule From the “clock” to the “calendar” • Written to: • Provide a clear “Benchmark” to physicians for determining the appropriateness of an inpatient admission. • Decrease prolonged observation stays • Decrease admission denials and RAC audits • Timing: • • • • Final rule out Implementation date: October 1, 2013 Audit and educate period (MAC) Final enforcement (RAC) – April 1, 2015 OLD INPATIENT DEFINITION: Hospital Manual: Chapter II - Coverage of Hospital Services 210. COVERED INPATIENT HOSPITAL SERVICES. Page 21.3/Rev. 525, 01-89 An inpatient is a person who has been admitted to a hospital for bed occupancy for purposes of receiving inpatient hospital services. Generally a person is considered an inpatient if formally admitted as an inpatient . . . . . . with the expectation that he will remain at least overnight and occupy a bed even though it later develops that he can be discharged or transferred to another hospital and does not actually use a hospital bed overnight. The physician should use a 24-hour period as a benchmark, i.e., he or she should order admission for patients who are expected to need hospital care for 24 hours or more, and treat other patients on an outpatient basis. However, the decision to admit a patient is a complex medical judgment which can be made only after the physician has considered a number of factors, including the patient's medical history and current medical needs, the types of facilities available to inpatients and to outpatients, the hospital's bylaws and admissions policies, and the relative appropriateness of treatment in each setting. NEW INPATIENT DEFINITION • A 2-midnight benchmark: FOR DOCTORS • An inpatient is expected to stay in the hospital at least two midnights: • 24 hours and 1 minute, or 47 hours and 59 minutes • “Clock” starts at triage • Outpatient time (ED or observation) counts • Inpatient stays < 2-MN not paid as an inpatient • except death, transfer, AMA, etc • A 2-midnight presumption: FOR REVIEWERS • If a patient met benchmark criteria, the admission will not be scrutinized by reviewers (RAC, MAC, etc) Under the Final Rule, CMS codified the definition of an inpatient admission at 42 C.F.R. § 412.3. An inpatient admission is appropriate and payable under Medicare Part A when: • ORDER: The patient is formally admitted to the hospital pursuant to an order for inpatient admission by a physician or other qualified practitioner eligible to admit; • The order is present in the medical record and is supported by the physician admission and progress notes; and • CERTIFICATION: The physician certifies the services are required to be provided on an inpatient basis, and the certification must include: • The order for inpatient admission; • A documented reason for the inpatient hospitalization for either inpatient medical treatment or diagnostic study, or special or unusual services for cost outlier cases; and • A statement that the inpatient hospital services were provided in accordance with new section 42 C.F.R. §412.3 (i.e., the order). Asserts the authority of Medicare policy over commercial tools: CMS Open Door Forum: IPPS and 2-midnight rule August 15, 2013 http://downloads.cms.gov/media/audio/081513InpHosAdm2MidnightProvSODF.mp3 George Mills: George Mills, Director, Provider Compliance Group, Medicare Staff “InterQual and Milliman are just tools, they are not Medicare policy; the RACs and MACs and CERT use them, but they are not definitive on Medicare rules and regulations and coverage decisions (Medicare rules) are what is definitive, not the InterQual or Milliman.” 42 OP ordered (obs) (obs) Outpatient Midnight #1 Discharge before MN #2 likely? + Maintain OP status. − Admit as IP (generally) Discharge before MN #3 likely? − Maintain IP status + + Midnight #2 IP criteria met amd 2MN benchmark? − Convert to OP status (code 44) Midnight #3 Maintain IP status • OBSERVATION PATIENTS: • If a patient is not going to be discharged before second midnight – admit on second day (don’t wait until third day). • Avoid IP conversion then discharge (abuse?) risk • Avoid risking 3 day SNF benefit • MAC and RACs will target patients for review for inpatient stays of 0-1 days IPPS and the 2MN Rule • May 15th, 2014: IPPS Proposed Rule • “Solicitation of comments on an alternative payment methodology under the Medicare program for short inpatient stays” • “Discussion of the process for submitting exceptions to the 2-midnight benchmark” • August 19th, 2014: IPPS Final Rule • Summary of comments • No change in short inpatient payment policy OPPS and the 2MN Rule • July 14, 2014: OPPS Proposed Rule • No meaningful change in the structure of payment for APC 8009 “Extended Assessment and Management” (observation) • Proposed 2015 payment = $1,287 • 2-MN rule: Proposed revision of the requirements for “physician certification” of inpatient admission under the 2-MN rule • Remove the requirement except for cases that are “outliers” – whose length of day is expected to go beyond 20 days. Reflections on the 2-MN Rule: • Unintended consequences of the 2-MN Rule – Procedural cases: • Not the intent of the 2-MN rule as stated • Big financial impact on hospitals • Beneficiary Impact with deductibles markedly increase • Example: EP Procedure from $1,068 to $6,224 • Is it a solution, or a symptom? • Solution – • Simplifies and reasserts the authority of CMS inpatient criteria • Prolonged outpatient stays – should decrease SNF, RAC issues • Symptom – “6-24 hour patients” • Observation services – does it address their needs adequately? • Unresolved issues – SNF, self administered meds, site of service C. FUTURE: U.S. Health Care - 2014 Health care costs . . . Patient co-pays are increasing 2013 Kiaser EmployerHealthBenefitsSurvey: http://kff.org/private-insurance/report/2013-employer-health-benefits/ “Hospitalized but Not Admitted” Sheehy AM et al. JAMA IM 2013 • Retrospective observational cohort study • Setting: Type 4 (No type 1 obs unit) • 566 bed Academic Medical Center (U. Wisc) • Time frame:36 months • Population: Hospitalized patients • 43,853 patients • 10.4% for “observation” • Mean LOS = 33.3 hours (17% over 48 hours) • Medical patients = 41.1 hours • More medical, elderly, and female patients • Hospital Margin = LOSS of $331 per case • Conclusion: “. . . observation status” • Are they missing something??? Variations in Observation Services – Wright, Hockenberry • Hospital characteristics are associated with the duration of observation services • Prolonged observation services increase patient costs Vankatesh A, Suter L; HSR Aug 2014, 1083-1087 Observation Service Settings: 52 Condition / Year / Author N Primary Outcome 1. Syncope / 14 / Sun * 124 ↓ admissions and LOS 2. Chest Pain / 10 / Miller * 110 ↓ Cost (stress MRI) 3. Atrial Fib / 08 / Decker 153 ↑ conversion to sinus 4. TIA / 07 / Ross 149 ↓ LOS and cost 5. Syncope / 04 / Shen 103 ↑ established diagnosis, ↓ admissions 6. Asthma / 97 / McDermot 222 ↓ admissions, no relapse ↑ 7. Chest Pain / 98 / Farkouh 424 No difference cardiac events 8. Chest Pain / 97 / Roberts 165 ↓ LOS and cost 9. Chest Pain / 96 / Gomez 100 ↓ LOS and cost *Added since published after this review ALOS Trend across State and Nation ED volumes OS Volumes OS LOS >8hr (average) % OS >24hr % OS >36hr % OS >48hr % OS >72hr OS=>IP admit rate Emory/Grady (Type 1 units) 185,901 7,199 17.2 hr 10.4% 0.1% 0.1 % 0% 13.1% Georgia (HCUP 2010) 4,194,602 162,375 27.2 hr 42.8% 23.0% 6.7% 1.5% 17.8% National (NHAMCS 2009-10) 133 million 1,216,000 ** 22.3 hr 29.0% 14.9% 6.9% 0.9% 23.2% 54 • U.S. Savings Potential from Type 1 Units: • Observation patients - $950 Million / year • 38% shorter stays • 44% lower admit rates • Short Inpatients - $8.5 Billion / year • 11.7% of all admissions • Savings potential – ED visits vs ED admissions: • Avoided ED visits = • Avoided ED admits = • Relative savings = (avoided: admits vs ED visits) $2.3-3.4 Billion/yr $5.5-8.5 Billion/yr 2.4-2.5 times greater • • • • • Observation Paradox . . . Consider E&M services: E/M Service: Clinic Visits Emergency (99281-5) Critical Care Inpatient Services • Observation Services (99217-20, 99234-6) Service Location: Clinics Emergency Departments Critical Care Units Inpatient Beds 2/3 of U.S. hospitals: Anywhere in the hospital??? 56 ACEP 2015 OPPS Proposal to CMS regarding observation • CMS should ask hospitals to report the “site of service” for observation patients (in a dedicated unit or not) • Apply time in observation to the SNF 3-day stay • Cover self administered medications • We agree - Remove the certification requirement from the 2MN rule Summary • To understand current 2-MN rule and observation policy issues, one needs to know their history • The 2-MN rule is a big change that will better define and value observation services • Like other E/M services, CMS needs to recognize the setting in which observation services occur. • If you don’t have an observation unit, you have a problem! References: • • • • • • • • • • Office of Inspector General. 2013. “Memorandum Report: Hospitals’ Use of Observation Stays and Short Inpatient Stays for Medicare Beneficiaries, OEI-02-12- 00040.”Washington, DC [accessed on September 10, 2013]. Available at http://oig.hhs.gov/oei/reports/oei-02-12-00040.asp Feng Z, Jung HY, Wright B, Mor V. The origin and disposition of Medicare observation stays; Medical Care; 2014, article in press Ross MA, Aurora T, Graff L, Suri P, O’Malley R, Ojo A, Bohan S, Clark C. State of the Art: Emergency Department Observation Units. Critical Pathways in Cardiology 2012;11: 128–138 Sheehy A, Graf B, Gangireddy S, et al. Hospitalized but not admitted: characteristics of patients with “observation status” at an academic center. JAMA Intern Med. 2013;173(21):1991-8. doi: 10.1001/jamainternmed.2013.8185. Wright, B., H.-Y. Jung, Z. Feng, and V. Mor. 2014. “Hospital, Patient, and Local Health System Characteristics Associated with the Prevalence and Duration of Observation Care.” Health Services Research 49 (4): 1088–1107. Hockenberry JM, Mutter R, Barrett M, Parlato J, Ross MA Factors associated with prolonged observation services stays and the impact of long stays on patient cost. Health Services Research. Dec 2013. 1-17 Ross MA, Hockenberry JM, Mutter R, Wheatley M, Pitts S. Protocol-Driven Emergency Department Observation Units Offer Savings, Shorter Stays, And Reduced Admissions. Health Affairs. Pub pending, 2013 Dec; 32(12):21492156 Venkatesh, A. K., B. P. Geisler, J. J. G. Chambers, C. W. Baugh, J. S. Bohan, and J. D. Schuur. 2011. “Use of Observation Care in US Emergency Departments, 2001 to 2008.” PLoS ONE 6 (9): e24326. Baugh, C.W., A. K.Venkatesh, J. A. Hilton, P. A. Samuel, J. D. Schuur, and J. S. Bohan. 2012. “Making Greater Use of Dedicated Hospital Observation Units for Many Short-Stay Patients Could Save $3.1 Billion a Year.” Health Affairs 31 (10):2314–23. Venkatesh, A. K . Suter LG. 2014. Observation “Services” and Observation “Care” – One Word Can Mean a World of Difference. Health Services Research 49 (4): 1083–1087.
© Copyright 2026 Paperzz