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ENGINEERING SCIENCE
Job description and selection criteria
Job title
Post-Doctoral Assistant in Acoustofluidic Devices
Division
Mathematical, Physical and Life Sciences Division
Department
Engineering Science
Location
Headington, Oxford
Grade and salary
Grade 7: £30,738 - £37,768 per annum
Hours
Full time
Contract type
Fixed-term for 2 years.
Reporting to
Dr Eleanor Stride
Vacancy reference
Additional
information
Introduction
The University
The University of Oxford is a complex and stimulating organisation, which enjoys an
international reputation as a world-class centre of excellence in research and teaching. It
employs over 11,000 staff and has a student population of over 22,000.
Our annual income in 2013/14 was £1,174.4m. Oxford is one of Europe's most innovative
and entrepreneurial universities: income from external research contracts exceeds £478.3m
p.a., and more than 80 spin-off companies have been created.
Oxford is a collegiate university, consisting of the central University and colleges. The central
University is composed of academic departments and research centres, administrative
departments, libraries and museums. There is a highly devolved operational structure, which
is split across four academic divisions, Academic Services and University Collections and
University Administrative Services. For further information, please see:
www.ox.ac.uk/staff/about_the_university/new_to_the_university/structure_of_university.
For more information please visit http://www.ox.ac.uk/about
The Mathematical, Physical, and Life Sciences Division
The Mathematical, Physical, and Life Sciences (MPLS) Division is one of the four academic
divisions of the University. In the results of the six-yearly UK-wide assessment of university
research, REF2014, the MPLS division received the highest overall grade point average
(GPA) and the highest GPA for outputs. We received the highest proportion of 4* outputs,
and the highest proportion of 4* activity overall. More than 50 per cent of MPLS activity was
assessed as world leading.
The MPLS Division's 10 departments and 3 interdisciplinary units span the full spectrum of
the mathematical, computational, physical, engineering and life sciences, and undertake
both fundamental research and cutting-edge applied work. Our research addresses major
societal and technological challenges and is increasingly focused on key interdisciplinary
issues. MPLS is proud to be the home of some of the most creative and innovative scientific
thinkers and leaders working in academe. We have a strong tradition of attracting and
nurturing the very best early career researchers who regularly secure prestigious fellowships
We have around 6,000 students and play a major role in training the next generation of
leading scientists. Oxford's international reputation for excellence in teaching is reflected in
its position at the top of the major league tables and subject assessments.
MPLS is dedicated to bringing the wonder and potential of science to the attention of
audiences far beyond the world of academia. We have a strong commitment to supporting
public engagement in science through initiatives including the Oxford Sparks portal
(http://www.oxfordsparks.net/) and a large variety of outreach activities. We also endeavour
to bring the potential of our scientific efforts forward for practical and beneficial application to
the real world and our desire is to link our best scientific minds with industry and public policy
makers.
For more information about the MPLS division, please visit: http://www.mpls.ox.ac.uk/
Engineering Science Department
Engineering teaching and research takes place at Oxford in a unified Department of
Engineering Science whose academic staff are committed to a common engineering foundation
as well as to advanced work in their own specialities, which include most branches of the
subject. We have especially strong links with computing, materials science and medicine. The
Department employs about 90 academic staff (this number includes 13 statutory Professors
appointed in the main branches of the discipline, and 25 other professors in the Department); in
addition there are 9 Visiting Professors. There is an experienced team of teaching support staff,
clerical staff and technicians. The Department has well-equipped laboratories and workshops,
which together with offices, lecture theatres, library and other facilities have a net floor area of
about 22,000 square metres.
Teaching
We aim to admit 160-170 undergraduates per year, all of whom take a 4-year Engineering
Science course leading to the MEng degree. The course is accredited at MEng level by the
major engineering institutions. The syllabus has a common core extending through the first two
years. Specialist options are introduced in the third year, and the fourth year includes further
specialist material and a major project.
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Research
The Department was ranked the top engineering department in the UK, as measured by overall
GPA, in the Research Excellence Framework 2014 exercise. We have approximately 350
research students and about 130 Research Fellows and Postdoctoral researchers. Direct
funding of research grants and contracts, from a variety of sources, amounts to an annual
turnover of approximately £19m in addition to general turnover of about £18m. The research
activities of the department fall into seven broad headings, though there is much overlapping in
practice: Thermofluids; Materials and Mechanics; Civil and Offshore; Information, Control and
Vision; Electrical and Optoelectronic; Chemical and Process; Biomedical Engineering.
For more information please visit:
http://www.eng.ox.ac.uk/
The University of Oxford is a member of the Athena SWAN Charter and holds an institutional
Bronze Athena SWAN award. The Department of Engineering Science holds a Departmental
Bronze Athena award in recognition of its efforts to introduce organisational and cultural
practices that promote gender equality in SET and create a better working environment for
both men and women.
The University of Oxford is also a corporate member of WISE.
Institute of Biomedical Engineering
Biomedical engineers, in partnership with clinical colleagues, can make a unique contribution
to addressing unmet needs in the prevention, early diagnosis or treatment of major diseases
in the 21st century. The Post-Doctoral Research Assistant will be based in laboratories within
the Institute of Biomedical Engineering (IBME), on the University’s medical research campus
adjacent to the Churchill Hospital (about a mile from the City centre). The Institute is a
dedicated research institute of the Department of Engineering Science, which is housed in a
2000 m2 building opened in April 2008. The Institute’s core mission is to develop novel
medical devices, technology and systems capable of delivering substantial healthcare benefit
through personalised monitoring and/or treatment.
Research at the IBME covers medical imaging, patient monitoring, ultrasound therapy,
physiological modelling, tissue engineering, orthopaedic engineering and drug delivery
systems. Most of this research is linked to clinical programmes in heart disease, stroke,
cancer, organ transplantation, regenerative medicine, acute care and the management of
chronic disease (e.g. asthma, diabetes). More information about the Institute and its
research programmes may be found at www.ibme.ox.ac.uk.
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Job description
Research topic
Therapeutic Imaging
Principal Investigator
/ supervisor
Dr Eleanor Stride
Project team
www.ibme.ox.ac.uk/
Project web site
www.ox.ac.uk/........
Funding partner
The funds supporting this research project are provided by the
EPSRC
Recent publications
Please refer to the website.
Description of the project
The project forms part of a wider research programme within the Institute of Biomedical
Engineering. The objective of the programme is to address the following key research
challenges to facilitate the integration of imaging and therapy:
- Development of combined agents for traceable drug delivery and other therapeutic
procedures.
- Investigation of the mechanisms by which imaging and therapeutic agents interact with
tissue at the cellular level.
- Design of technology for fabrication, localisation and activation of therapeutic agents.
Overview of the role
The specific role of the person appointed will be to design and fabricate microfluidic devices
incorporating piezoelectric (or other ultrasound generating) elements for the generation of
solid, liquid or gas-filled particles for use as agents in imaging and/or stimuli responsive drug
delivery.
Responsibilities/duties
Responsibilities/duties
1.
Designing microfluidic devices incorporating ultrasound generating components that
for the purpose of fabricating particles for use in imaging and/or drug delivery.
2.
Generating and characterising different types of particle using appropriate techniques
including (but not restricted to): quantitative fluorescence microscopy, laser scattering,
zeta potential and acoustic measurements; and if appropriate, atomic force or electron
microscopy.
3.
Collaborating, where appropriate, with other researchers to assess the efficacy of drug
delivery vehicles and/or ultrasound exposure protocols being developed within the IBME
in phantoms, in vitro or in vivo models.
4.
5.
Investigating the potential for scale up/multiplexing of the devices.
Attending conferences and presenting recent work and progress reports at meetings
with industrial and academic collaborators.
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6.
Preparing papers for publication.
7.
Helping with the supervision of DPhil, MSc and MEng students where appropriate.
8.
Contributing to the day-to-day running of an experimental laboratory.
Selection criteria
Essential
1.
PhD in a relevant area of physics or engineering.
2.
High degree of competence in design and fabrication of microfluidic devices.
3.
High degree of competence in experimental ultrasonic systems.
4.
Experience with particle characterisation techniques including (but not limited to):
dynamic light scattering, zeta potential measurement, standard fluorescence and
confocal microscopy.
5.
High degree of competence (but not limited to): fluorescent labelling of membrane
components and monitoring of ion channel activity.
6.
Good oral and written communication and presentation skills.
7.
Demonstrated ability to work in a multidisciplinary team of researchers with a
variety of both physical and life sciences backgrounds.
8.
Strong evidence of research achievement to date, as might be demonstrated by a
good publication record and/or academic distinctions and conference prizes.
Desirable
1.
Prior experience with other advanced characterisation techniques such as atomic
force microscopy (AFM) and electron microscopy.
2.
Prior experience with the culture and handling of cells and characterisation techniques
including in microfluidic systems.
3.
Prior experience of biomedical ultrasound.
4.
Prior experience of data processing ideally using Matlab.
5.
Prior experience of instrument interfacing and control, ideally with knowledge of
Labview.
Pre-employment screening
Please note that the appointment of the successful candidate will be subject to standard preemployment screening, as applicable to the post. This will include right-to-work, proof of
identity and references. All applicants must read the candidate notes on the University’s preemployment screening procedures, found at:
https://www.ox.ac.uk/about/jobs/preemploymentscreening/.
The University’s policy on retirement
The University operates an employer justified retirement age for all academic and academicrelated posts (any grade above grade 5), for which the retirement date is the 30 September
immediately preceding the 68th birthday.
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The justification for this is explained at:
www.admin.ox.ac.uk/personnel/end/retirement/revisedejra/revaim/
For existing employees any employment beyond the retirement age is subject to approval
through the procedures outlined at:
www.admin.ox.ac.uk/personnel/end/retirement/revisedejra/revproc/
Working at the University of Oxford
For further information about working at Oxford, please see:
www.ox.ac.uk/about_the_university/jobs/research/
How to apply
If you consider that you meet the selection criteria, click on the Apply Now button on the
‘Job Details’ page and follow the on-screen instructions to register as a user. You will then
be required to complete a number of screens with your application details, relating to your
skills and experience. When prompted, please provide details of two referees and indicate
whether we can contact them at this stage. You will also be required to upload a CV and
supporting statement which explains how you meet the selection criteria for the post. The
supporting statement should explain your relevant experience which may have been gained
in employment, education, or you may have taken time away from these activities in order to
raise a family, care for a dependant, or travel for example. Your application will be judged
solely on the basis of how you demonstrate that that you meet the selection criteria outlined
above and we are happy to consider evidence of transferable skills or experience which you
may have gained outside the context of paid employment or education.
Please save all uploaded documents to show your name and the document type.
All applications must be received by midday on the closing date stated in the online
advertisement.
Information for priority candidates
A priority candidate is a University employee who is seeking redeployment owing to the fact
that he or she has been advised that they are at risk of redundancy, or on grounds of illhealth/disability. Priority candidates are issued with a redeployment letter by their employing
departments.
If you are a priority candidate, please ensure that you:
- attach your redeployment letter to your application
- explain in your covering letter how you meet the selection criteria for the post.
Should you experience any difficulties using the online application system, please email
[email protected]
Further help and support is available from
http://www.ox.ac.uk/about_the_university/jobs/support/
To return to the online application at any stage, please click on the following link
www.recruit.ox.ac.uk
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Please note that you will be notified of the progress of your application by automatic e-mails
from our e-recruitment system. Please check your spam/junk mail regularly to ensure that
you receive all e-mails.
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