The role of time and risk preferences in adherence to physician advice on health behaviour change Abstract Changing physical activity and dietary behaviour in chronic disease patients is associated with significant health benefits but is difficult to achieve. An often used strategy is for the physician or other health professional to encourage behaviour changes by providing advice on the health consequences of such behaviours. However, adherence to advice on health behaviour change varies across individuals. This paper uses data from a population-based cross-sectional survey of 1,849 individuals with chronic disease to explore whether differences in individuals’ time and risk preferences can help explain differences in adherence. Health behaviours are viewed as investments in health capital within the Grossman model. Physician advice plays a role in the model in that it improves the understanding of the future health consequences of investments. It can be hypothesised that the effect of advice on health behaviour will depend on an individuals’ time and risk preference. Within the survey, which measured a variety of health-related behaviours and outcomes, including receipt and compliance with advice on dietary and physical activity changes, time preferences were measured using financial planning horizon, and risk preferences were measured through a commonly used question which asked respondents to indicate their willingness to take risks on a 10-point scale. Results suggest that time preferences play a role in adherence to physical activity advice. While time preferences also play a role in adherence to dietary advice, this effect is only apparent for males. Risk preferences do not seem 1 to be associated with adherence. The results suggest that increasing the salience of more immediate benefits of health behaviour change may improve adherence. Key words: adherence, time preference, risk preference 2 Introduction Health behaviours such as physical activity and dietary behaviour are major risk factors for chronic disease. It is well known that it is challenging to change these behaviours. An often used strategy is for the physician or other health professional to encourage health behaviour changes by providing advice on the health consequences of such behaviours. Evidence suggests that physician advice1 is effective in changing health behaviours (e.g. Loureiro and Nayga, 2007; Kenkel and Terza, 2001). However, adherence to advice on health behaviour change varies considerably across individuals (WHO, 2003). To devise incentives for better adherence, it is crucial to gain a better understanding of the underlying factors that are correlated with whether patients adhere. Many different determinants of health behaviours and barriers to health behaviour change have been identified in the literature (Fitzgerald and Spaccarotella, 2009). This paper draws on economic theory and explores whether differences in individuals’ time and risk preferences can help explain differences in adherence to physician advice. A number of papers have highlighted the potential role played by time preference in adherence (Reach, 2008; Elliott et al, 2008; Christensen-Szalanksi and Northcraft; 1985; Feldman et al, 2002). Adherence to recommended health behaviour changes and medication regimens is an intertemporal decision with costs and benefits occurring at different points in time. Adherence generally represents a trade-off between short-term costs and long-term benefits. For example, adopting smoking cessation advice involves a trade-off between costs now in terms of withdrawal symptoms in exchange for future health benefits in terms of reduced mortality and morbidity. Time preferences are key parameters in intertemporal models determining how individuals trade- 1 In the remainder of the paper the term physician advice includes advice from physician or any other health professional. 3 off outcomes over time. It could therefore be hypothesized that individuals’ time preference would influence whether they adhere to recommended health behaviour changes. Another feature of the intertemporal decision is that the future health consequences are uncertain. For example an individual does not know with certainty whether adopting smoking cessation advice will lead to future health improvements (they may still experience lung cancer for example). Individuals’ attitude to risk could therefore also play a role in adherence. The aim of this paper is to investigate the relationship between adherence to physician advice in health behavior changes and individuals’ time and risk preferences in a sample of chronic disease patients (heart disease, hypertension, diabetes, stroke). Most previous studies have examined the correlation between health behaviours (smoking, obesity, excessive alcohol use, drug use) and time and risk preferences in relatively healthy samples , comparing for example the time and risk preferences of smokers with those of non-smokers in general population or student samples (Lawless et al., 2013, Story et al, 2014). The contribution of this paper is two-fold. Firstly, this study focuses on chronic disease patients rather than general population samples. Understanding the determinants of health behavior is of particular importance in this group given the larger health effects associated with these behaviors in this group. Secondly, this study examines whether time and risk preferences are associated with how individuals adhere to physician advice, that is, whether time and risk preferences are associated with changes in behavior. Examining adherence has the potential to inform the development of more effective self-management interventions in chronic disease. Previous research into the relationship between adherence to physician advice on health behavior change and time and risk preference is very limited. Chapman et al (2001) investigated the correlation between time preference and medication adherence in individuals with 4 hypertension and high cholesterol. The results were mixed in that the correlations did not always have the expected sign and/or were not statistically significant. Brandt and Dickinson (2013) found a statistically significant relationship between adherence to asthma control medication and time and risk preferences in a small sample of college students. This paper uses a larger population-based survey and examines the role of time and risk preferences in people with a range of chronic conditions (heart disease, hypertension, diabetes, stroke). Conceptual framework The conceptual framework draws on the canonical model of demand for health, the Grossman model. In this model health is viewed as both a consumption good and an investment good. Individuals can invest in (produce) health through investing resources and time. Choices regarding level of health investments are made so that the expected discounted utility over the lifetime is maximised. Grossman did not specifically consider the impact of different time preference rates. Given that health investments such as physical activity typically involve short-term costs and longterm benefits, it can be deduced that a higher time preference rate will reduce the level of health investment. Most studies testing this hypothesis empirically have found a significant association between time preferences and a range of health behaviours (Lawless et al., 2013). The Grossman model was formulated under conditions of certainty and risk preferences were therefore not relevant. Dardanoni and Wagstaff (1987) introduced uncertainty into the Grossman model. Pfeifer (2012) explored the impact of differences in risk preferences within a simplified Grossman model. Risk preferences affect the subjective expectations of health and productivity effects of health investments. Individuals who are more risk averse have higher subjective 5 perceptions of health risks and as a result higher expectations of the earning reductions. As a result, a risk averse individual will make more health investments compared to a risk seeking individual. Empirical evidence suggests a relationship between risk preferences and health behaviours (see for example Barsky et al, 1997 and Pfeifer, 2012). Kenkel and Terza (2001) argue that physician advice enters the model because investment in health depends on the predicted health consequences. Physician advice will improve the understanding of the parameters of the health production function. Note that this assumes that the individual will be receptive to the advice and will accurately interpret the advice. Evidence suggests that most individuals underestimate the health consequences of unhealthy behaviours in terms of both probability and magnitude and as a result underestimate the benefits of health investments (Weinstein, 2000). Provision of information is therefore likely to lead to a higher overall expected utility of health investments. However, given that health benefits tend to occur relatively far into the future, the increase in discounted expected utility is lower for individuals with high time preference rates compared to individuals with a low time preference rate. It is also lower for risk seeking individuals. The increase in expected utility resulting from a better understanding of the probabilities of the health consequences is lower in risk seeking individuals as they are less sensitive to risk compared to risk averse individuals. It is therefore hypothesised that individuals with high time preference rates and risk seeking individuals are less likely to adhere to physician advice compared to individuals with low time preference rates and risk averse individuals. It should be noted that an individual’s perception of the probability and magnitude of the benefits of health investments may also be a function of their time and risk preferences. For example, individuals who are risk averse may be more likely to overestimate the risks of unhealthy 6 behaviours. However, this would also result in higher levels of investment. That is, the direct and this more indirect effect of time and risk preferences on levels of investment work in the same direction. Methods Data Adherence to physician advice on dietary and physical exercise behaviour changes is modelled as a function of time and risk preferences. Data were collected as part of a larger cross sectional survey of chronic disease patients in Western Canada, the Barriers to Care for People with Chronic Health Conditions (BCPCHC) survey (Weaver et al, 2014). The sampling frame of the BCPCHC survey consisted of individuals living in Western Canada (Alberta, British Columbia, Manitoba, Saskatchewan) who were at least 40 years of age and who self-identified as having at least one of four chronic diseases (hypertension, diabetes, heart disease and stroke) in the 2011 Canadian Community Health Survey (CCHS). Using these criteria 2,400 respondents were identified for participation in the BCPCHC, of whom 2,316 were still in scope at the time of survey administration. The response rate was 80%, yielding a final sample of 1,849 individuals. Data were collected by telephone using Computer Assisted Telephone Interviews (CATI) by Statistics Canada. The questions for the survey were designed by subject matter experts in Statistics Canada Health Analysis Division and project researchers including the authors of this paper. Qualitative testing of the questionnaire was undertaken in the form of focus group testing. This included interviews and focus groups with participants having a mix of chronic conditions. With participant consent, responses from the BCPCHC survey were linked to their corresponding 2011 CCHS responses to provide more detailed socio-demographic information, including household income. 7 Table 1 shows the descriptive characteristics of the estimation sample. Due to missing data our sample reduces to 1637 individuals in the case of physical activity advice and 1634 in the case of dietary advice. Notably income was missing for around 30% of the total sample. For those individuals, income was imputed using a nearest neighbour technique including postal code median income, household size and approximate household income range (Yeung and Thomas, 2012). Adherence variables Adherence is measured using self-reported adherence questions (Campbell et al 2014). Respondents were first asked whether they received advice from their doctor or other health professional. If they stated they had received advice, they were asked whether they had ever changed their behaviour. If so, they were then asked whether they still did and at what level (none, some, most or all of the time). Appendix 1 shows the wording of the adherence questions. The focus of this paper is on the two types of advice that are most often received by all patients in the sample: advice to change dietary and physical activity behaviours (Campbell et al, 2014). The dietary advice relates to advice on changing the types of foods individuals eat such as fruits and vegetables, fish or lean meats, foods high in fibre or foods low in fat to help manage their chronic disease. The physical activity advice relates to advice on exercising or participating in physical activities to help manage their chronic disease. Changes in dietary and physical activity behaviours have been shown to reduce morbidity and mortality (Lichtenstein et al, 2006; Boule et al, 2001; Blumenthal et al, 2000). 8 The adherence variables are dichotomised into non-adherence (never or no longer adhere). A binary variable is created that equals one if the individual does not adhere (never or no longer adhere) and zero otherwise. As very few individuals stated that they no longer adhered these were merged with those who never adhered. A number of robustness checks are run on the classification of adherence in the sensitivity analysis. Self-report measures have been used extensively in the literature as they are practical and inexpensive but they are subject to social desirability and recall bias (WHO, 2003). The validity of the measures used in this study is explored by testing whether adherence is associated with Body Mass Index (BMI), physical activity behaviour and diet quality. These measures were collected as part of the Canadian Community Health Survey to which the data were linked. Time and risk preference In the economics literature risk preferences are generally measured using lotteries and time preferences using intertemporal trade-offs. Due to constraints on survey length and the mode of data collection (CATI), it was not possible to use lotteries or intertemporal trade-offs. These questions tend to be cognitively complex and relatively time consuming. Time and risk preferences are therefore measured using proxies in this survey. Time preferences are measured using financial planning horizon. Planning horizon has been used in several studies as a proxy for time preference (for example Picone et al, 2004; Khwaja et al, 2007; Samwick, 1998). Adams and Nettle (2009) show that planning horizon and time preference rate, measured using hypothetical trade-offs over time, are correlated. There are other factors that 9 are likely to be associated with planning horizon such as socio-economic status which are controlled for in the analysis. The financial planning horizon question asks respondents: “In planning your savings and spending which of the following time periods is most important to you?” The respondent has the option of choosing: 1) next week; 2) next few months; 3) next year; 4) next two to four years; 5) next five to ten years; and 6) more than ten years ahead. Risk preferences are measured through a commonly used risk scale. The scale is used in a number of household surveys such as the British Household Panel Survey (BHPS). The question asks respondents to indicate their willingness to take risks on a ten point scale, with one indicating unwilling to take risks, and ten indicating fully prepared to take risks. The wording of the general risk question is as follows: “Are you generally a person who is fully prepared to take risks, or do you try to avoid taking risks? Dohmen et al (2011) showed that the general risk question accurately predicts behaviour within incentive compatible lottery experiments. Other covariates Other variables of interest in this analysis included chronic condition (categorized as hypertension, diabetes, heart disease and stroke); gender; age group (categorized as 40-64 years, 65-74 years and 75 years and older); education (dichotomized as less than post-secondary or post secondary); household income (dichotomized as <$30,000 or $30,000 and greater); marital status (dichotomized as married/common law or widowed/separated/divorced /single); rural residence 10 (dichotomized as living in a population centre or a rural area); severity (dichotomized as 1 chronic condition or more than 1 chronic condition); having a usual doctor (dichotomized as yes or no) and the number of times the respondent saw a family doctor or general practitioner for their chronic condition in the past year. Respondents were also asked if they had enough information to manage their chronic condition and were classified as “yes” if they responded that they had all they had information they needed and “no” otherwise. Some of the covariates are likely to be correlated with time and risk preferences and including the covariates may therefore reduce the size and significance of the time and risk preference coefficients. For example, time preference may affect education which in turn affects nonadherence. However, exclusion of the covariates in the estimation may result in omitted variables bias in the likelihood of non-adherence. To examine whether time and risk preference are correlated with the covariates, willingness to take risk and planning horizon were regressed as a function of the covariates. Appendix 2 shows that risk preferences (willingness to take risk) are correlated with age, sex, education and not having enough information to manage their condition. Time preferences (planning horizon) are correlated with age, income and number of times they saw a family doctor or general practitioner. To understand how the covariates impact the time and risk preferences coefficients we first estimate a basic model with only time and risk preferences included and gradually introduce the covariates. Method of analysis The main hypotheses will be tested using probit regression analysis. The dependent variable is non-adherence to advice on health behaviour change (never or no longer adhere). The independent 11 variables are time and risk preferences and the covariates. The covariates consist of factors that are known to be associated with adherence and include socio-economic factors (gender, age, education, income, marital status, rural residence), condition related factors (severity – defined as having more than one chronic condition), and healthcare system factors (whether the individual has a regular medical doctor and number of times seen or talked to a family doctor or general practitioner for their chronic condition in the last 12 months) (Kardas et al, 2013). Non-adherence to advice is modelled separately for the two types of advice, eating certain foods and physical activity. Whilst the error terms in the two regression models may be correlated as non-adherence to the two types of advice may be influenced by common unobservable factors such as health attitude, no efficiency gains are made by using seemingly unrelated regression methods (such as the bivariate probit) as the regression models have identical independent variables (Greene, 2003). We model receipt of advice and non-adherence using a probit model which can be derived from a latent or unobserved variable model. Let y* denote the latent variable such that 𝑦 ∗ = 𝛽0 + ∑𝑘𝑗=1 𝛽𝑥 + 𝜀, (1) where 𝜀~𝑁(0,1) and y*=1 if y*>0; 0 otherwise. Then the probability of receipt of advice or nonadherence, y, is given by 𝑃(𝑦 = 1|𝑥) = 𝑃(𝑦 ∗ > 0|𝑥) = Φ(𝛽0 + ∑𝑘𝑗=1 𝑥), (2) 12 where Φ(𝑧) = ∫ 𝜙(𝑣)𝑑𝑣 is the cumulative normal distribution function with standard normal density 𝜙(𝑣) = (2𝜋)−1⁄2 𝑒𝑥𝑝(−𝑧 2 ⁄2). This probit model is estimated by maximum likelihood using the software STATA. Receipt of advice and non--adherence is modelled as function of time preference (TP), risk preference (RP) and a range of covariates (D): 𝑅𝑒𝑐𝑒𝑖𝑝𝑡 𝑜𝑓 𝑎𝑑𝑣𝑖𝑐𝑒 = 𝛼0 + 𝛼1 𝑇𝑃 + 𝛼2 𝑅𝑃 + 𝛼3 𝐷 + 𝜀 (3) 𝑁𝑜𝑛 − 𝑎𝑑h𝑒𝑟𝑒𝑛𝑐𝑒 = 𝛾0 + 𝛾1 𝑇𝑃 + 𝛾2 𝑅𝑃 + 𝛾3 𝐷 + 𝜀 (4) Marginal effects are reported as the parameters α and will not allow inference of the magnitude of the impact on the likelihood of receipt of advice and non-adherence. To explore gender differences, the models are run separately for females and males. The analysis is also rerun for hypertension patients only. The health consequences of hypertension tend to occur farther into the future compared to the other chronic diseases (diabetes, stroke and heart disease). It could therefore be hypothesised that time preferences in particular play a more important role in adherence to advice on behaviour changes in hypertension patients. To explore the validity of the self-reported adherence variables, BMI, physical activity and diet quality are regressed on the adherence measures and a range of covariates (gender, age, education, income, marital status, rural residence and severity (having more than one chronic condition)). BMI is measured using self-reported height and weight. Physical activity is measured using a series of questions about the types and intensity of leisure time activity. Answers to these questions 13 were converted into values for total daily energy expenditure (kcal/kg/day) and further categorized into three levels (active, moderately active and inactive). For this analysis the variable was dichotomized into active (incorporating moderately active coded as zero) and inactive (coded as one). Diet quality is measured using a validated measure based on four questions on fruit and vegetable intake (Manuel et al., 2012, Manuel 2013). The four dietary variables were combined into an index based on their individual relationship with mortality that was observed in previous studies (Manuel et al., 2012; Manuel et al., 2014). A composite score was constructed that assigned one point for daily fruit and vegetable consumption excluding fruit juice up to a maximum of eight points. High potato intake (-2 points for ≥7 servings of potato weekly (men) or ≥5 (women) times/week), no carrot intake (-2 points) and high fruit juice intake (-2 points per daily frequency of fruit juice consumption exceeding once/day up to a maximum of -10 points) were penalized, as they were shown to be independently associated with mortality. The diet score was calculated by adding two baseline points to the sum of total points. The resulting score ranged from 0-10 and for this analysis is coded zero for worst diet (score 0 to 3.5), one for medium diet (score 3.5 to 6.5) and two for best diet (score 6.5 to 10.0). BMI is modelled using linear regression, physical activity is modelled using probit regression and diet quality using ordered probit regression. Results Figure 1 shows the distribution of the time and risk preference variables. There is considerable heterogeneity in time and risk preferences in this sample of chronic disease patients. The correlation between time and risk preferences is 0.040 (p-value 0.10). Table 2 shows the adherence variables. The majority of patients have received physician advice (advice from their doctor or 14 health professional) on eating certain foods and physical activity. Non-adherence (never or no longer adhere) is higher in physical activity (14.6%) compared to eating certain foods (7.6%). Table 3 shows the marginal effects of the probit regressions for receipt of advice. Older patients are less likely to have received dietary advice whilst seeing a health professional more often and disease severity (having more than one chronic condition) increases the probability of receiving dietary advice. Receipt of physical activity advice is also a function of age and disease severity. Having a regular doctor increases the probability of receiving physical activity advice whilst having a household income of less than $30,000 reduces the probability of receiving physical activity advice. Table 4 shows the marginal effects of the probit regressions for non-adherence. Risk preferences are not statistically significant in any of the models. Time preferences (planning horizon) are associated with non-adherence to physical activity advice. Individuals with a longer planning horizon (more future oriented) are more likely to adhere (i.e. less likely to not adhere) to advice on physical activity. The marginal effects show that at the mean value a unit increase in planning horizon is associated with a 1.9% increase in the probability of adhering to advice on physical activity. In the case of adherence to advice on eating certain foods, planning horizon is not statistically significant. Table 5 shows the full models by gender and for hypertension patients only. Planning horizon has a consistent effect on non-adherence across the models in the case of physical activity advice. 15 Gender differences are found in the case of adherence to advice on eating certain foods. Planning horizon is statistically significant in case of males but not for females. A number of robustness checks on the classification of adherence and the time and risk preference variables were run. Adhering some of the time was reclassified as non-adherence. Time preference was no longer significant in this case suggesting that time preference explains the upper tail of the adherence distribution only. Time and risk preferences were also entered as binary variables (planning horizon shorter than a year and risk response greater than five) as well as dummy variables for each of the categories (four in the case of time preference and ten in the case of risk preferences). Similar results were found across the alternative specifications. It would have been interesting to explore non-adherence across the two behaviours concurrently but sample sizes are too small to conduct any robust analyses. Table 6 shows the results for exploring the validity of the adherence variable. As expected, individuals who do not adhere to physical activity advice have a higher BMI and are more likely to report that they are not physically active. Individuals who stated that they did not adhere to dietary advice are more likely to have a lower diet quality score but no significant relationship was found with BMI. Discussion This paper explored the role of risk and time preferences in non-adherence to physician advice on health behaviour change in a sample of chronic disease patients. Adherence to dietary and physical 16 activity advice was examined. The results showed that risk preferences were not associated with adherence in any of the models. Time preferences were associated with adherence to physical activity advice. The marginal effects were relatively small which is in line with other literature examining the relationship between time preference and health behaviours (Lawless et al., 2013). There was a gender effect in case of adherence to dietary advice. Time preferences were associated with adherence in males only. Jusot and Khlat (2013) found a similar gender difference in the relationship between time preference and smoking. There are a number of limitations to this study. Both adherence and time and risk preferences are likely to have been measured with some error. Adherence to physician advice on health behaviour changes was self-reported. Evidence suggests that respondents overstate adherence (WHO, 2003). However, adherence was shown to be correlated with BMI, physical activity behaviour and diet quality. Whilst these measures were also self-reported they have been shown to predict a range of objectively measured health outcomes and diseases, including diabetes, stroke, cardiovascular disease, hospitalization and mortality (Rosella et al. 2011; Manuel et al. 2015; Taljaard et al. 2014; Manuel et al. 2014; Manuel et al. 2012) The survey only asked whether people were given certain types of advice and no information was available on the level of detail of this advice, how it was delivered, how long ago and how often they received advice. We only observed adherence for those respondents who stated that they received advice from their physician. Individuals may be less likely to state that they received advice if they did not adhere and this may have introduced a bias in the adherence analysis. This could be explored in future research by obtaining a more objective measure of receipt of advice such as a measure based on medical records. Due to the fact that only a few respondents reported they no longer adhered, it was not possible to examine 17 whether the effect of time and risk preferences is similar for the decision to change behaviour following physician advice and for the decision to maintain the behaviour changes. This would be interesting to explore in future research with larger samples. The question also arises whether planning horizon and the risk scale are valid proxies for time and risk preferences. Empirical evidence suggests that the proxies are correlated with more robust measures of risk and time preferences (Dohmen et al, 2011; Adams and Nettle, 2009). More precise measures of time preferences would have allowed the investigation of alternative discounting models such as the quasi-hyperbolic discounting model. Evidence suggests that individuals have present bias, that is, they attach enhanced significance to outcomes that occur in the present (Frederick et al., 2002). This can explain why individuals often plan behaviour change in the future but fail to follow through with this. For example, they plan to go to the gym next week but when next week arrives the temptation of the sofa is too strong. The role of present bias in adherence to physician advice would therefore be interesting to explore. It is also unclear whether time and risk preferences for money are the most appropriate type of preferences when the interest is in health investments. However, time preferences for monetary outcomes tend to be correlated with time preference for health outcomes (see for example, Lazarro et al, 2001). Moreover the proxies have been shown to be correlated with health behaviours (see for example Dohmen et al, 2011). Further research examining adherence using time and risk preferences for health outcomes is required. Finally, as the study is based on cross sectional data the correlation between time preference and adherence does not necessarily reflect causal relationships. Standard economic theory assumes that time preferences are exogenous and, if this assumption holds, it could be argued that the correlation reflects a causal effect of time preferences on adherence. However, time preferences may be endogenous and change over the lifecycle (Becker and Mulligan, 1997). 18 This study provides some support for the role of time preference in adherence to advice on health behaviour change. This suggests that adherence can be improved by increasing the salience of the more immediate benefits of health behaviour change. Health behaviour advice often consists of information on the longer term health benefits. Individuals who are more present oriented, place relatively less value on longer term benefits than individuals who are more future oriented. However, health behaviour changes often also have shorter term benefits and increasing the salience of these more immediate benefits would be effective in particular in individuals who are present oriented. Increasing the salience of the connection between current activities and future outcomes may also be effective. For example, Hall and Fong (2003) showed that a ‘time perspective’ intervention improved physical activity levels in young adults. The intervention consisted of education and activities to make people more aware of the connections between present behaviour and future outcomes of physical activity and explained how people often forget about these connections. Future research could explore whether such an intervention would also be effective in chronic disease patients. References Adams J, Nettle D. 2009. Time perspective, personality and smoking, body mass, and physical activity: An empirical study. British Journal of Health Psychology 14: 83–105 Becker GS, Mulligan CB. 1997. The endogenous determination of time preference. The Quarterly Journal of Economics 112; 729-758. 19 Barsky RB., Kimball MS., Juster FT., Shapiro MD. (1997) Preference parameters and behavioral heterogeneity: an experimental approach in the health and retirement study. Quarterly Journal of Economics 112; 537-579. Blumenthal JA, Sherwood A, Gulette EC, Babyak M, Waugh R (2001) Exercise and weight loss reduce blood pressure in men and women with mild hypertension: effects on cardiovascular, metabolic, and hemodynamic functioning. Arch Intern Med 160(13): 1947-58. Boule NG, Haddad E, Kenny GP, Wells GA, Sigal RJ (2001) Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA 286(10): 1218-1227. Brandt S, Dickinson MS. (2013). Time and risk preferences and the use of asthma controller medication. Pediatrics 131: e1204-e1210. Campbell JT, Ronksley PE, Manns BJ, Tonelli M, Sanmartin C, Weaver RG, Hennessy D, KingShier K, Campbell T, Hemmelgarn BR. (2014) The association of income with health behavior change and disease monitoring among patients with chronic disease. Plos One 9 (4). Chapman GB, Brewer NT, Coups EJ, Borwlee S, Leventhal H, Leventhal EA. (2001) Value for the future and preventive behaviour. Journal of Experimental Psychology 7: 235-250. Christensen-Szalanski JJJ, Nortcraft GB (1985) Patient compliance behaviour: the effect of time on patients’ values of treatment regimens. Social Science and Medicine 21: 263-273. Dardoni V, Wagstaff A (1990) Uncertainty and the demand for medical care. Journal of Health Economics 9: 23-28. Dohmen T, Falk A, Huffman D, Sunde U,Schupp J, and Wagner GG (2011). Individual Risk Attitudes: Measurement, Determinants and Behavioral Consequences, Journal of the European Economic Association 9: 522-550. 20 Elliott RA, Shinogle JA, Peele P, Bhosle M, Hughes DA. (2008) Understanding medication compliance and persistence from an economics perspective. Value in Health 11: 600-610. Feldman SR, Chen GJ, Hu, JY, Fleischer AB. (2002) Effects of systematic asymmetric discounting on physician-patient interactions: a theoretical framework to explain poor compliance with lifestyle counselling. BMC Medical Informatics and Decision Making 2:8. Fitzgerald N, Spaccarotella K. (2009). Barriers to a Healthy Lifestyle: From Individuals to Public Policy—An Ecological Perspective. Journal of Extension 47: 1. Frederick S, Loewenstein G, O'Donoghue T. (2002). Time Discounting and Time Preference: A Critical Review. Journal of Economic Literature, 40, pp. 351-401. Greene. (2003) Econometric Analysis. Prentice Hall. Hall PA, Fong GT. (2003) The effects of a brief time perspective intervention for increasing physical activity among young adults. Psychology and Health 18: 685-706. Heckman, J. (1979). Sample selection bias as a specification error. Econometrica 47 (1): 153–61 Jusot F, Khlat M. (2013) The role of time preferences in smoking inequalities: a populationbased study. Addictive behaviors 38: 2167-2173. Kardas P, Lewek P, MatyjaszczykM. (2013) Determinants of patient adherence: a review of systematic reviews. Front Pharmacol. 2013; 4: 91. Kenkel D, Terza JV. (2001) The effect of physician advice on alcohol consumption: count regression with an endogenous treatment effect. Journal of Applied Econometrics 16: 165184. Khwaja a, Silverman D, Sloan F. (2007). Time preference, time discounting and smoking decisions. Journal of Health Economics 26: 927-949. 21 Lawless L, Drichoutis AC, Nayga RM. (2013) Time preferences and health behaviour: a review. Agricultural and Food Economics 1: 17. Lazaro A, Barberan R, Rubio E. (2001) Private and social time preferences for health and money: an empirical estimation. Health Economics 10: 351-356. Lichtenstein AH, Appel LJ, Brands M., Carnethon M, Daniels S, (2006) Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation 114(1): 82-96. Loureiro ML, Nayga RM (2007) Physician’s advice affects adoption of desirable dietary behaviors. Review of Agricultural Economics 29: 318-330. Manuel DG, Perez R, Bennett C, Rosella L, Taljaard M, et al. (2012) Seven More Years: The impact of smoking, alcohol, diet, physical activity and stress on health and life expectancy in Ontario. Toronto: Institute for Clinical Evaluative Sciences and Public Health Ontario. Manuel DG (2013) The burden of unhealthy living in ontario: the impact of smoking, alcohol, diet, physical inactivity and stress on life expectancy. Healthcare quarterly 16(1): 1618.Manuel DG, Perez R, Bennett C, Rosella L, Choi B (2014) 900,000 Days in Hospital: The Annual Impact of Smoking, Alcohol, Diet, and Physical Activity on Hospital Use in Ontario. Toronto, ON: Institute for Clinical Evaluative Sciences. Manuel DG, Tuna M, Perez R, Tanuseputro P, Hennessy D, Bennett C, Rosella L, Sanmarin C, van Walraven C, Tu JV. Predicting stroke based on health behaviours: Development of the Stroke Population Risk Tool (SPoRT). PLoS One. 2015. 10(12). Pfeifer C. (2012) A Note on Smoking Behavior and Health Risk Taking. Nordic Journal of Health Economics. 22 Picone G, Sloan F, Taylor D. 2004. Effects of Risk and Time Preference and Expected Longevity on Demand for Medical Tests. Journal of Risk and Uncertainty 28: 39-53. Reach G. (2008) A novel conceptual framework for understanding the mechanism of adherence to long term therapies. Patients Preferences and Adherence 2: 7-19. Rosella LC, Manuel DG, Burchill C, et al. A population-based risk algorithm for the development of diabetes: development and validation of the Diabetes Population Risk Tool (DPoRT). J Epidemiol Community Health 2011; 65:613–20. Samwick AA. 1998. Discount heterogeneity and social security reform. Journal of Development Economics 57: 117-146. Story G, Vlaev I, Seymour B, Darzi A, Dolan RJ (2014) Does temporal discounting explain unhealthy behaviour? A systematic review and reinforcement learning perspective. Frontiers in Behavioural Neuroscience 76. Taljaard M, Tuna M, Bennett C, Perez R, Rosella L, Tu JV, Sanmartin , Hennessy D, Tanuseputro P, Lebenbaum M, Manuel D. Cardiovascualr Disease Population Risk Tool (CVDPoRT): predictive algorithm for assessing CVD risk in the community setting. A study protocol. BMJ Open. 2014. Oct 23; 4(10). Weaver RG, Manns BJ, Tonelli M, Sanmartin C, Campbell DJT, Ronksley PE, Lewanczuk R, Braun TC, Hennessy D, Hemmelgarn B. (2014) Access to primary care and other health care use among western Canadians with chronic conditions: a population-based survey. Canadian Medical Association Journal Open 2(1). Weinstein ND. (2000). Perceived probability, perceived severity, and health- protective behavior. Health Psychology 19: 65–74. 23 WHO (2003) Adherence to long-term therapies: evidence for action. http://apps.who.int/medicinedocs/en/d/Js4883e/ Yeung CW, Thomas S (2012) Income imputation for the Canadian Community Health Survey. Statistics Canada, Ottawa. 24 Table 1. Descriptive characteristics of the study sample* All N Chronic conditions Hypertension Diabetes Heart disease Stroke Sex Male Female Age 40-64 years 65-74 years 75+ years Education Post-secondary education Less than post-secondary education Income $30,000+ <$30,000 Marital status Married/common-law Widowed/separated/divorced/single Rurality Urban Rural Severity One condition More than one condition Usual doctor Yes No Enough info to manage condition Yes No % Males N % Females N % 1363 468 381 117 83.3 28.6 23.3 7.2 584 256 195 51 79.2 34.7 26.4 7.3 779 212 186 66 86.7 23.6 20.7 6.9 738 899 45.1 54.9 --- --- --- --- 628 509 500 38.4 32.1 30.5 324 221 193 43.9 29.9 26.2 304 288 307 33.8 32.0 34.2 906 732 55.4 44.6 424 314 57.5 42.5 482 417 53.6 46.4 1233 552 69.1 30.9 636 163 79.6 20.4 597 389 60.6 39.5 910 727 55.6 44.4 495 243 67.1 32.9 415 484 46.2 53.8 1228 409 75.1 24.9 536 202 72.6 27.4 692 207 76.9 23.1 1059 579 64.7 35.3 451 287 61.1 38.9 608 291 67.6 32.4 1550 87 94.7 5.3 692 46 93.8 6.2 858 41 95.4 4.6 1126 511 Mean 3.69 68.8 31.2 Range 0-104 496 242 Mean 3.73 67.2 32.8 Range 0-48 630 269 Mean 3.65 70.1 29.9 Range 0-104 Times seen family doctor or general practitioner for their chronic condition in the past year * estimation sample for physical activity advice. Descriptive statistics for dietary advice sample are similar and available on request. 25 Table 2. Descriptive statistics advice and adherence variables Eat certain foods (n=1,634) Physical activity (n=1,637) All Male Female All Male Female N (%) N (%) N (%) N (%) N (%) N (%) No 594 (36.3) 251 (34.1) 343 (38.2) 429 (26.2) 188 (25.5) 241 (26.8) Yes 1040 (63.7) 485 (65.9) 555 (61.8) 1210 (73.8) 550 (74.5) 658 (73.2) Never or no longer adhere 79 (7.6) 42 (8.7) 37 (6.7) 177 (14.6) 72 (13.1) 105 (16.0) Adhere some/most/ all of the time 961 (92.4) 443 (91.3) 518 (93.3) 1031 (85.2) 478 (86.9) 553 (84.0) Advice Adherence 26 Table 3. Regression results for receipt of advice Eating certain foods Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income <$30,000 Married/common law Rural place of residence N Pseudo R2 ME 0.010 0.003 SE 0.007 0.005 ME 0.004 -0.001 -0.069** -0.191** 0.025 SE 0.008 0.005 0.030 0.030 0.024 ME 0.007 -0.001 -0.083** -0.216** 0.017 -0.051 0.013** SE 0.008 0.005 0.030 0.031 0.025 0.056 0.004 -0.005 0.099** 0.026 0.025 1634 0.0011 1634 1634 0.0215 1634 1634 0.0374 1634 ME 0.010 0.011** SE ME 0.005 0.009** -0.095** -0.187** -0.009 SE ME 0.005 0.010** -0.111** -0.211** -0.013 -0.187** 0.000 SE ME 0.006 -0.001 -0.081** -0.209** 0.011 -0.053 0.013** SE 0.008 0.005 0.030 0.032 0.025 0.056 0.004 -0.006 0.099** 0.021 -0.042 0.004 0.026 1634 0.0389 0.026 0.025 0.025 0.031 0.027 0.028 Physical activity Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income<$30,000 Married/common law Rural place of residence N Pseudo R2 * 0.007 0.004 0.007 0.004 0.029 0.029 0.022 0.010 0.086** 1639 0.0051 1639 0.0286 1630 0.0437 0.007 0.004 0.029 0.030 0.022 0.056 0.002 0.023 0.022 ME 0.003 0.008* -0.105** -0.188** -0.023 -0.176** 0.001 0.010 0.089** -0.036 -0.057** -0.003 0.008 1639 0.0484 SE 0.007 0.004 0.029 0.031 0.023 0.056 0.002 0.023 0.022 0.023 0.028 0.025 0.025 significant at 10% level; ** significant at 5% level 27 Table 4. Regression results for non-adherence Eating certain foods Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income <$30,000 Married/common law Rural place of residence N Pseudo R2 ME -0.008 -0.002 SE 0.005 0.003 ME -0.006 -0.002 0.026 0.044* 0.025 SE 0.005 0.003 0.021 0.025 0.017 ME -0.006 -0.002 0.029 0.050** 0.025 0.047 -0.001 SE 0.005 0.003 0.021 0.025 0.017 0.046 0.002 0.013 -0.015 1040 0.0044 1040 0.0145 0.018 0.017 1040 0.0204 ME -0.006 -0.002 0.026 0.036 0.031* 0.043 -0.001 SE 0.005 0.003 0.021 0.025 0.017 0.045 0.002 0.012 -0.018 0.013 0.029 0.009 0.017 1040 0.0297 0.018 0.016 0.017 0.022 0.018 0.019 Physical activity Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income<$30,000 Married/common law Rural place of residence N Pseudo R2 * ME -0.021** -0.005 SE 0.006 0.004 ME -0.021** -0.005 0.005 0.012 -0.021 SE 0.006 0.004 0.024 0.026 0.021 ME -0.020** -0.004 -0.003 0.002 -0.028 -0.009 -0.001 0.042* 0.053** 1208 0.0130 1208 0.0144 1208 0.0242 SE 0.006 0.004 0.024 0.025 0.020 0.049 0.003 0.023 0.022 ME -0.019** -0.003 -0.003 -0.006 -0.027 -0.014 -0.001 0.042* 0.052** 0.049** 0.000 -0.003 -0.022 1208 0.0303 SE 0.006 0.004 0.024 0.026 0.021 0.047 0.003 0.023 0.022 0.022 0.025 0.022 0.022 significant at 10% level; ** significant at 5% level 28 Table 5. Regression results for non-adherence by gender and for hypertension patients Eating certain foods Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income<$30,000 Married/common law Rural place of residence N Pseudo R2 Female ME SE 0.008 0.006 -0.002 0.004 0.011 0.027 0.051* 0.033 Male ME SE -0.023** 0.007 -0.002 0.005 0.057* 0.033 0.012 0.034 0.091 -0.001 0.080 0.002 0.000 -0.002 0.046 0.004 0.007 -0.018 0.016 0.030 -0.015 0.005 555 0.0397 0.022 0.021 0.022 0.026 0.023 0.024 0.021 -0.023 0.014 0.032 0.035 0.030 485 0.0663 0.026 0.024 0.025 0.036 0.028 0.029 Hypertension ME SE -0.007 0.005 0.002 0.003 0.043* 0.024 0.051** 0.029 0.039** 0.019 0.055 0.051 -0.001 0.002 0.023 -0.021 0.017 0.028 0.011 0.011 859 0.0474 0.019 0.017 0.018 0.024 0.019 0.020 Physical activity Planning horizon Willingness to take risk Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income<$30,000 Married/common law Rural place of residence N Pseudo R2 * Female ME SE -0.020** 0.009 -0.005 0.006 -0.010 0.034 -0.022 0.036 Male ME SE -0.019** 0.009 0.000 0.006 0.007 0.034 0.021 0.040 -0.025 -0.002 0.070 0.004 0.002 0.000 0.065 0.004 0.049 0.099** 0.034 0.045 -0.018 -0.048 658 0.0454 0.032 0.033 0.030 0.036 0.033 0.030 0.034 0.007 0.063 -0.059 0.008 -0.004 550 0.0283 0.032 0.030 0.031** 0.032 0.032 0.032 Hypertension ME SE -0.018** 0.007 -0.002 0.005 0.021 0.027 -0.001 0.029 -0.011 0.023 0.009 0.055 0.003 0.004 0.046* 0.043* 0.061** -0.044 0.027 -0.033 1009 0.0340 0.025 0.024 0.024 0.026 0.025 0.024 significant at 10% level; ** significant at 5% level 29 Table 6. Regression results for validity of non-adherence variables Non-adherence Age 65-74 years Age 75+ years Male > 1 chronic condition Education post-secondary Income<$30,000 Married/common law Rural place of residence Constant N Adjusted R2 Pseudo R2 * significant at 10% level; Eating certain foods BMI Diet quality Coefficient SE Coefficient SE -0.018 0.610 -0.405** 0.134 -1.612** 0.391 -0.014 0.084 -4.819** 0.443 0.121 0.095 -0.016 0.347 -0.529** 0.075 2.520** 0.344 0.111 0.074 -0.132 0.342 -0.296** 0.073 -0.192 0.423 -0.126 0.091 0.892** 0.375 -0.325** 0.080 0.085 0.383 -0.021 0.081 29.406 0.385 1087 1032 0.1273 0.0460 ** BMI Coefficient 2.067** -1.888** -5.105** -0.248 2.404** 0.078 -0.228 1.065** 0.089 29.482 1253 0.1475 Physical activity Physically active SE Coefficient SE 0.434 0.872** 0.108 0.368 -0.072 0.086 0.405 0.136 0.095 0.322 -0.136* 0.075 0.322 0.175** 0.075 0.321 0.132* 0.075 0.389 0.195** 0.091 0.346 -0.031 0.081 0.357 0.089 0.083 0.361 -0.308 0.084 1291 0.0627 significant at 5% level 30 Figure 1. Histograms time and risk preferences Planning horizon (time preferences) Willingness to take risk (risk preferences) Unwilling to take risks Fully prepared to take risks 31 Appendix 1. Survey questions Adherence questions The next questions are about things that a doctor or other health professional may have suggested to help manage your ^CONDITION, and the things that people might do as a result of being diagnosed Has a doctor or other health professional ever suggested / recommended: eating certain foods such as fruits and vegetables, fish or lean meats, foods high in fibre or foods low in fat to help manage your chronic disease? Yes No Did you ever change type of foods you eat, for example choosing more fruits and vegetables, fish or lean meats, foods high in fibre or foods low in fat to help manage your chronic condition? Yes No Are you still doing this: All of the time Most of the time Some of the time None of the time Has a doctor or other health professional ever suggested / recommended: that you exercise or participate in physical activities to help manage your chronic condition? Yes No Did you ever exercise or participate in physical activities to help manage your chronic condition? Yes No 32 Are you still doing this All of the time Most of the time Some of the time None of the time Planning horizon In planning your saving and spending, which of the following time periods is most important to you? The next week The next few months The next year The next 2 to 4 years The next 5 to 10 years More than 10 years ahead Risk Are you generally a person who is fully prepared to take risks, or do you try to avoid taking risks? On a scale ranging from 1 (Unwilling to take risks) to 10 (Fully prepared to take risks), where would you place yourself? 1: Unwilling to take risks 2 3 4 5 6 33 7 8 9 10: Fully prepared to take risks. 34 Appendix 2. Regression results for time and risk preferences Age 65-74 years Age 75+ years Male No usual doctor Times seen doctor Not enough info to manage condition > 1 chronic condition Education post-secondary Income <$30,000 Married/common law Rural place of residence Constant N Adjusted R2 * Willingness to take risk Coefficient SE -0.028 0.146 -0.349** 0.155 0.727** 0.125 0.234 0.269 0.005 0.014 -0.331** 0.130 -0.117 0.129 -0.532** 0.125 -0.285* 0.150 0.043 0.134 0.220 0.139 5.413 0.153 1639 0.0502 Planning horizon Coefficient -0.162* -0.341** 0.015 -0.180 -0.021** -0.040 -0.122 -0.144* -0.334** -0.085 0.034 3.941 1639 0.0339 SE 0.095 0.100 0.081 0.175 0.009 0.084 0.084 0.081 0.097 0.087 0.090 0.099 significant at 10% level; ** significant at 5% level 35
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