CRAVINGS? FIX YOUR LEPTIN!
Phuong Anh Tran
Adipose Derived Hormone
Functions: regulating appetite, food intake and metabolism.
Also regulates puberty onset and pregnancy.
Secreted by adipose tissues
1.
2.
3.
4.
Adipose tissue absorbs glucose, & lipids
Releases leptin
Leptin binds to neurons in hypothalamus
α-melanocyte-stimulating hormone synthesizes
Result: sense of satiation
Sources: (“Cravings?” “Leptin,” “The Stomach-”)
HOMEOSTATIC CONTROL OF ADIPOSE TISSUE MASS
 Fat mass fails -> plasma leptin concentration falls -> stimulating appetite
 Fat mass increases -> leptin levels increase -> suppressing appetite
(Source: Nature Medicine)
LEPTIN RESISTANCE
 High levels of leptin = “Brain is starved, the body is obese”
Heart disease, obesity, diabetes
Source: (Leptin Hormones)
ANALOGY
Air-conditioning
Too hot and heating stops
Too cold and heating begins
 Works Cited
 "Cravings? Fix Your Leptin!" Wellness Mama. N.p., n.d.Web. 10 Feb. 2014.
<http://wellnessmama.com/5356/cravings-fix-your-leptin/>.
 "Leptin Hormone & Supplements: Do They Work for Obesity & Weight
Loss?" WebMD. WebMD, n.d.Web. 09 Feb. 2014.
<http://www.webmd.com/diet/features/the-facts-on-leptin-faq?page=2>.
 "Leptin: This Hormone Makes Counting Calories Irrelevant."
Mercola.com. N.p., n.d.Web. 10 Feb. 2014.
<http://articles.mercola.com/sites/articles/archive/2009/06/20/thishormone-makes-counting-calories-irrelevant.aspx>.
 Mandal, Ananya, Dr. "What Is Leptin?" What Is Leptin? News-Medical, n.d.
Web. 10 Feb. 2014. <http://www.news-medical.net/health/What-isLeptin.aspx>.
 "The Stomach Is a Source of Leptin." National Center for Biotechnology
Information. U.S. National Library of Medicine, n.d.Web. 10 Feb. 2014.
<http://www.ncbi.nlm.nih.gov/pubmed/9723619>.