Research Institute GOVERNMENT REDUCES PUBLIC PHARMACEUTICAL EXPENDITURE IN HUNGARY: RATIONAL DECISION IN CHALLENGING ECONOMIC PERIOD? Background: Methods: Scarcity of public resources, especially in challenging economic times, draws attention to the expenditure on pharmaceuticals. Utilisation of innovative drugs is considered to be one of the main contributors for the growth of pharmaceutical expenditures. Price of innovative drugs converges to a narrow price corridor, due to international price referencing and parallel trade in the EU. The proportion of pharmaceuticals spending can be very different for each country. Huber and Orosz maintained that OECD (Organisation for Economic Co-operation and Development) countries with lower income tend to spend a greater proportion on pharmaceuticals (1), partly because labour costs are usually adjusted to local price levels, which reduce the relative weight of health services in cost calculation. Middle income countries have to purchase innovative drugs on the same international reference price as developed countries, whilst their total health budget is much lower. However, policy and scientific reports on pharmaceutical expenditure usually compare pharmaceutical spending among all OECD countries, regardless their economic status. Only few compared pharmaceutical spending separately in high, middle and low income countries (2). To compare health expenditures across countries at a given point in time, it is necessary to convert data from national currency to a common unit, such as USD. Many previous studies adjust health care expenditures with purchasing power parity (PPP). PPP, however, does not seem to be the most appropriate for pharmaceuticals, because of the abovementioned price convergence. We completed an international cross sectional and cluster analysis based on OECD Health Data 2010 and longitudinal analysis of public pharmaceutical expenditure in Hungary. European and American OECD member countries with a population above 300 000 inhabitants were included in the study. All expenditures are in official USD exchange rate. Cluster analysis was performed to compare high income countries (GDP/ capita above 30’000 USD) and middle income countries (GDP/capita under 30’000 USD). Difference in characteristics of the two groups of countries were assessed by Mann-Whitney-Wilcoxon test. Level of significance were set to 0.05 unless stated otherwise. Aims: Our objective was to assess the current level of pharmaceutical expenditure in Hungary by taking into account the economic status of the country and benchmarks from other OECD countries with special focus on Visegrad V4 countries (Czech Republic, Slovakia, Poland, Hungary). Parameters Average of countries above GDP 30.000 USD/capita Difference (high vs middle income countries) P-value 1599 464 372 230 141 7.90 5117 1328 694 412 282 10.00 3517 864 323 182 140 2.10 <0.001** <0.001** <0.001** 0.001** <0.001** 0.002** 2.24 2.65 0.41 0.653 total private total public private Total health care exp. / capita (USD, 2008) pharm & med device exp. /capita (USD, 2008) Health expenditure Private health expenditure Total pharm & med device exp. Public pharm & med device exp. Private pharm & med device exp. Within GDP (%) Total pharm & med device exp. Within total health care exp. (%) Private pharm & med device exp. Average of countries under GDP 30.000 USD/capita Within total pharm & med device exp. (%) Within total private health exp. 1.89 1.41 -0.48 0.039* 1.11 0.83 -0.29 0.185 0.75 0.57 -0.18 0.046* 23.58 14.14 -9.44 <0.001** 41.85 37.48 39.93 23.59 -1.92 -13.90 0.928 Results: Table 1 indicates considerable differences in health care spending between high and middle income countries. Middle income countries spend less proportion of their GDP on health (7.9% vs. 10%, p=0.002) compared to high income countries; whilst the proportion of pharmaceutical expenditure from total health spending is greater (23.58% vs. 14.14%, p<0.001). As a consequence, middle income countries spend higher percentage of their lower GDP on pharmaceuticals, compared to high income countries (1.89% vs. 1.41%, p=0.039). The proportion of private expenditure on pharmaceuticals is also higher within GDP% and total private health expenditure (0.75% vs. 0.57%, p=0.046 and 37.48% vs. 23.59%, p=0.016, respectively). According to Table 2, total health care expenditure in Hungary (1119 USD) is lower than the average of V4 countries (1241 USD). Nominal pharmaceutical expenditure is higher in Hungary (353 USD) compared to the average of V4 countries (316 USD), Slovakia, however, spends more on drugs and medical devices (387 USD). Public pharmaceutical expenditure is also higher in Slovakia (276 USD), compared to Hungary (200 USD). The percentage of total pharmaceutical and medical device expenditure within total health expenditure (31.6%) and within GDP (2.3%) is the highest in Hungary (Table 3). However, GDP% of public pharmaceutical expenditure is considerably lower in Hungary (1.3%) compared to Slovakia (1.6%). Private pharmaceutical expenditure is the highest in Hungary (153 USD) within V4 countries (average of V4: 129 USD). The share of private pharmaceutical expenditure is higher in Hungary (43.3%) than in Slovakia (28.7%). Poland with 61.8% share of private pharmaceutical expenditure has the lowest total expenditure on pharmaceuticals (220 USD). Figure 1 indicates the nominal and real public expenditure on pharmaceuticals in Hungary. Without new cost containment measures, the annual nominal growth of public pharmaceutical expenditures would be 11.3%, and only 1.0% in real expenditure between 1994 and 2010. The government plans to reduce the public pharmaceutical expenditure to 65% by 2014. The annual growth then would be 6.6% nominally between 1994 and 2014, whilst the growth of real expenditure would be negative (-1.9%). Total health care exp / GDP / capita (USD, capita 2008) (USD, 2008) 51685 5117 694 412 10.0 % Average of countries under GDP 30.000 USD/ capita 19819 1599 372 230 7.9 % Average of V4 countries 16960 1241 316 187 7.3 % Czech Republic Poland Slovakia Hungary 21059 13856 17555 15368 1498 972 1400 1119 305 220 387 353 188 84 276 200 7.1 % 7.0 % 7.8 % 7.3 % 0.016* Private Private pharm Private Public pharm & & med device health pharm & med device expenditure / exp. within med device exp / capita capita (USD, total pharm & exp. Within (USD, med device 2008) GDP (%) 2008) exp. (%) Table 2. Comparison of two clusters with the V4 countries I. Public pharmaceutical expenditures in Hungary (1994-2014) Annual nominal growth: 6,6% Annual real growth: -1,9% Nominal expenditure (BN HUF) 14.1 % 1.4 % 0.8 % 281 1327 39.9% 23.6 % 1.9 % 1.1 % 141 463 41.8% 25.7 % 1.9 % 1.1 % 129 320 42.9% Average of V4 countries Czech Republic Poland 20.4 % 1.5 % 0.9 % 117 261 38.3 % 22.6 % 1.6 % 0.6 % 136 269 61.8 % Slovakia 28.1 % 2.2 % 1.6 % 111 426 28.7 % Hungary Health expenditure within GDP % 31.6 % 2.3 % 1.3 % Table 3. Comparison of two clusters with the V4 countries II. 153 324 43.3% Real Expenditure (BN HUF, ref.: 1994) Billion HUF Average of countries above GDP 30.000 USD/capita Average of countries under GDP 30.000 USD/ capita Total pharm & med device exp. within GDP (%) Public pharm & med device exp. / capita (USD, 2008) Average of countries above GDP 30.000 USD/capita Table 1. Comparison of high and middle income countries (*significant at p=0.05, **significant at p=0.01 Total pharm & med device exp. within total health care exp. (%) pharm & med device exp. / capita (USD, 2008) 4 995 996 997 998 999 000 001 002 003 004 005 006 007 008 009 010 011* 012* 013* 014* 9 9 2 1 1 1 1 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 Figure 1. Public pharmaceutical expenditure in Hungary between 1994 and 2014 – the effects of the planned pharmaceutical expenditure reduction on the average annual growth Discussion: Middle income countries have to pay almost the same uniform price for innovative drugs as high income countries due to manufacturers’ response to international price referencing and parallel trade. Conversely, costs of other health care services are lower mainly due to lower salaries of health care professionals. It can be misleading to compare the Hungarian pharmaceutical expenditures to the average of OECD countries. Cluster analyses of countries with similar economic status should be used for comparison of pharmaceutical spending. However, cost containment initiatives are usually based on comparison with the OECD average. Cost-containment of public pharmaceutical spending was very successful in the last fifteen years in Hungary. The burden of pharmaceutical market growth has been shifted to private households. The proposed public budget cut translates to over 30% decrease in real public pharmaceutical spending from 1994 to 2014. As morbidity and mortality indicators of the Hungarian population are extremely unfavourable, current evidences and international benchmarks do not justify significant reduction of the public pharmaceutical budget. References: 1. Huber M, Orosz E.: Health expenditure trends in OECD countries, 1990-2001. Health Care Financ Rev, 2003; 25: 1-22. 2. Hopkins S.: Health Expenditure Comparisons: Low, Middle and High Income Countries, The Open Health Services and Policy Journal, 2010; 3: 111-117. TODAY’S RESEARCH FOR TOMORROW’S HEALTH
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