PDMS Chip Interface
product datasheet
Description
Main Benefits
Specification
Cross-Sectional View
Geometry
Design Guidelines
Fabrication Guidelines
PDMS Chip Interface Starter Kit
Custom Options
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The Dolomite Centre Ltd
Part name
Part number
PDMS Chip Interface
3200232
PDMS Chip Slide 50 x 25 mm (pack of 10)
3200264
PDMS Chip Slide 75 x 25 mm (pack of 10)
3200275
PDMS Chip Interface Starter Kit
3200273
Description
The PDMS Chip Interface (Part No. 3200232) allows users to create fast and reliable
fluidic connections to PDMS-on-glass devices. The interface is designed to be used with a
PDMS device (fabricated by the user) mounted to a PDMS Chip Slide with pre-drilled
holes for fluidic connection (2 sizes available).
Designing a PDMS device to fit the Dolomite format is quick and easy when following the
design guidelines. Fabrication can be carried out using existing methods and equipment.
The PDMS Chip Interface is compatible with the Multiflux® Linear Connector 4-way (Part
No. 3000024) to provide 4 or 8 fluidic connections from 1/16” OD tubing to the PDMS
chip.
PDMS Chip Interface (Part No. 3200232)
Full assembly of the PDMS Chip with two
PDMS Chip Interfaces and two Linear
Connectors 4-way (Part No. 3000024)
PDMS_chip_interface_product_datasheet
PDMS Chip Slide (Part No. 3200275)
Full assembly of the PDMS Chip with one
PDMS Chip Interface and one Linear
Connector 4-way (Part No. 3000024)
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The Dolomite Centre Ltd
Main Benefits
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Robust and reliable connections
Provides a standard format for PDMS chip connections
Ideal for research use
Time savings in fabrication: no requirement to punch holes in PDMS
Time savings in use: no downtime due to leaks
Extends chip lifetimes
Widens applications for PDMS chips outside of research labs
Quick connect/disconnect
Low dead volume
Good microscope access
Accommodates wide range of PDMS device heights
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The Dolomite Centre Ltd
Specification
Specification
Number of fluidic connections
Compatible glass slide dimensions
Glass slide hole size
PDMS Chip Interface (Part No. 3200232)
4 or 8*
50 x 25 x 1.3mm or 75 x 25 x 1.3mm (L x W x H)
Ø0.5mm
PDMS chip thickness options
Up to 6mm
PDMS chip width options
Up to 15mm
PDMS chip length options
10 – 44mm (50 x 25mm slide)
10 – 69mm (75 x 25mm slide)
Outside diameter of connection tubing
Inside diameter of connection tubing
Connection tubing material
Operating pressure
Operating temperature range of seal
Wetted materials
Connector materials
1.6mm (1/16inch)
0.25, 0.5 or 0.8mm
PTFE, FEP
5bar**
-15 to 150°C***
Glass, PDMS, PTFE (or FEP), and perfluoroelastomer
PEEK, Stainless Steel 316
*8 fluidic connections requires 2 x PDMS Chip Interface (Part No. 3200232) and 2 x Multiflux®
Linear Connector 4-way (Part No. 3000024)
**Based on tests at 21C, PDMS chip may delaminate at lower pressure
***Assumes external surfaces of connector are at room temperature and tube I.D. <0.5mm.
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Cross-sectional view
Linear Connector 4-way
(Part No. 3000024)
Glass slide 50 x 25 mm
(Part No. 3200264)
Left: Cross-sectional view
with PDMS Chip Slide 50 x 25
mm (Part No. 3200264)
Below: Cross-sectional view
with PDMS Chip Slide 75 x 25
mm (Part No. 3200275)
PDMS Chip Interface (Part No. 3200232)
PDMS microfluidic device
Linear Connector 4-way
(Part No. 3000024)
Glass slide 75 x 25 mm
(Part No. 3200275)
PDMS Chip Interface (Part No. 3200232)
PDMS microfluidic device
PTFE or FEP tubing
Perfluoroelastomer seal
Hole through glass slide
Microchannel in PDMS
Detailed View of Sealing Interface
PDMS_chip_interface_product_datasheet
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Geometry
Geometry of PDMS Chip with one PDMS Chip Interface and one Linear Connector 4-way (Part No. 3000024)
PDMS_chip_interface_product_datasheet
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The Dolomite Centre Ltd
Geometry of PDMS Chip with two PDMS Chip Interfaces and two Linear Connectors 4-way (Part No. 3000024)
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Design Guidelines
In order to design a compatible PDMS device for use with the PDMS Chip Interface, it is
necessary to follow 5 simple steps:
1. Decide if you require 4 fluidic connections or 8 fluidic connections.
a. 4 connections can be made with one PDMS Chip Interface and one Linear
Connector 4-way. Two chips can be mounted to each slide.
b. 8 connections can be made with two PDMS Chip Interfaces and two Linear
Connectors 4-way. One chip can be mounted to each slide.
2. Decide if your device length fits onto the standard 50 x 25 mm slide or if you
require the longer 75 x 25 mm slide.
3. Design pad features in PDMS (recommended Ø1 mm) at a pitch of 3 mm to align
with Ø0.5 holes in glass slide. These are the inlet and outlet ports.
4. Design outer dimensions of PDMS device ensuring that the boundaries are within
the maximum width and length specified.
a. Maximum width is 15 mm. The maximum distance from outside port to
PDMS side edges is 3 mm.
b. Maximum length depends on the number of fluidic connections (step 1)
and the slide size selected (step 2). The maximum distance from inlet and
outlet ports to PDMS back edge is 3 mm.
5. Design channel features in PDMS ensuring that all features to be viewed are
positioned at least 3 mm from the inlet and outlet ports. Visible features should be
outside of the red box in the diagram below.
PDMS_chip_interface_product_datasheet
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The Dolomite Centre Ltd
Key design dimensions of PDMS replica if 4 fluidic connections are required and
2 chips of equal length are mounted onto the PDMS Chip Slide
Key design dimensions of PDMS replica if 8 fluidic connections are required (1 chip
mounted onto PDMS Chip Slide)
PDMS_chip_interface_product_datasheet
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The Dolomite Centre Ltd
Fabrication Guidelines
Fabrication of the PDMS device can be carried out using existing soft lithographic
methods and equipment:
1. Fabricate a photoresist master (spin coat photoresist onto a silicon wafer, expose
and develop).
2. Degas the PDMS mixture. Then cast the PDMS onto the master, cure and peel
the wafer of PDMS replicas from the photoresist master. The PDMS height should
be no greater than 6 mm.
3. Dice the wafer of PDMS replicas into individual chips ensuring that outer
dimensions are within the allowed size.
4. Ensure that bonding surfaces of the glass and PDMS are clean then expose both
surfaces to O2 plasma.
5. Align PDMS pad features to holes in the glass slide by eye or using low
magnification eyepiece or viewer. Apply light pressure to create bond.
6. The completed PDMS chip can then be used with the PDMS Chip Interface.
Described above is a typical soft lithography process, but alternative methods may be
used for the creation of channel features in the PDMS.
Example of PDMS replica mounted onto PDMS Chip Slide
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PDMS Chip Interface Starter Kit
The PDMS Chip Interface Starter Kit (Part No. 3200273) contains the required
components to start using the Multiflux® PDMS chip connection system.
The starter kit includes:
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1 x PDMS Chip Interface – Part No. 3200232
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1 x PDMS Chip Slide 50 x 25mm (pack of 10) – Part No. 3200264
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1 x Multiflux® Linear Connector 4-way – Part No. 3000024
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1 x Fluid Tube PTFE 1/16” OD, 0.5mm I.D, 10m Length – Part No. 3200067
PDMS Chip Interface Starter Kit (Part No. 3200273)
Custom Options
Dolomite can offer custom connection systems for individual applications including thin
layer glass slides for high magnification microscopy. Microscope holders are also
available on request. The range of Dolomite services available covers all aspects of the
development process from concept studies and feasibility testing to the design of
commercial instruments. Please contact Dolomite to discuss your application.
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The Dolomite Centre Ltd
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