TESTING OF HYPOTHESIS-1 Ph.D. Coursework Lecture Prof.K.K.Achary BASIC CONCEPTS • Every research study is seeking answers to questions of scientific interest. • Ex: What is the optimum dose of a drug to be administered in case patients showing some symptoms of mental illness? • Whether drug A is more effective than drug B for treating disease X? • Does training the healthcare workers improve their commitment to service? • In all these examples , the researcher wants to study scientifically and establish the answers. • The answer to these questions should be sought based on evidence, i.e., using sample data to support your research study. • The research studies usually involve estimation of a population parameter or comparing two or more populations responding to an intervention/treatment. • The purpose of hypothesis testing is to aid the researcher in reaching a conclusion concerning a population by examining a sample from that population. • Definitions: • A hypothesis may be defined as a statement about one or more populations. • It is concerned about the parameters of the population. • Researchers are concerned about two types of hypotheses : research hypotheses and statistical hypotheses. • Research hypothesis is the conjecture or supposition that motivates the research. This may be based on researchers own experience or motivated by work carried out by other researchers. • Research hypothesis leads to statistical hypothesis. • Statistical hypotheses are hypotheses that are stated in such a way that they may be evaluated by appropriate statistical techniques. • The process of testing a statistical hypothesis can be seen as a logical sequence of actions and decisions. • The important steps in this sequence are the following: • DATA: It must be understood as it forms the basis of testing procedure. The type of data –discrete or continuous, nominal or ordinal/categorical are to be decided as this will decide the test to be used. • ASSUMPTIONS: Assumptions are very important as they provide the basis for using a particular test procedure. Common assumptions are normality, equality of variances, independence of samples etc. • HYPOTHESIS: There are two hypotheses involved in hypothesis testing - null hypothesis and alternative hypothesis. • Null hypothesis is the hypothesis to be tested; it is the hypothesis of no difference • It is a statement of agreement with the conditions assumed to be true in the population. It is the complement of the conclusion the researcher is seeking. • Ex: Suppose the researcher wants to show that drug A is more effective than drug B. • Then the null hypothesis is a statement about equal effect of the two drugs. • Drug A is equal or less effective than drug B • Null hypothesis is designated by the symbol H0 • The other hypothesis is called the alternative hypothesis. • It is a statement about what the researcher believes to be true if the test of null hypothesis using the sample data rejects the null hypothesis • It is same as the research hypothesis and shown by the symbol H1 (orH A ) • Examples: in determining the dose level,we have to say about the the mean dose level for the population. For this case, the null hypothesis is : H 0 : μ 250mg • The alternativ e hypothesis could be stated in one of the following forms H1 : 250(or 250 ) or H1 : 250 • Your research hypothesis should be placed as the alternative hypothesis • The null hypothesis should contain a statement of equality/inequality, either or or • The null hypothesis is the hypothesis to be tested. • The null and alternative hypotheses are complementary • Neither hypothesis testing nor statistical inference,in general, leads to the proof of a hypothesis; it merely indicates whether the hypothesis is supported or not supported by the available data. • When we fail to reject a null hypothesis, we do not say that it is true,but that it may be true. • Not rejecting H 0 neednot imply H 0isTRUE TEST STATISTIC • A test statistic is a function of the sample data.Depending on the hypothesis to be tested, the test statistic is defined/derived. • It serves as a decision maker , since the decision to reject or accept the null hypothesis depends on the magnitude of the test statistic. • General rule for writing a test statistic: relevant stat. - hypothesis ed parameter test statistic standard error of relevant stat. x 0 z , known, 0 is / n hypothesis ed value of parameter Distribution of test statistic • The key to statistical inference is the sampling distribution – the distribution of the relevant statistics used to formulate the test statistic. • If the hypothesis is about the population mean, then the relevant statistic is the sample mean. The sampling distribution of the sample mean plays the key role in constructing the test statistic. • The distribution of test statistic is derived when the null hypothesis is true. • The test statistic shown below has standard normal distribution. x 0 z , known, 0 is / n hypothesis ed value of parameter Decision Rule • Consider all values of the test statistic and plot them on a line.We can form the set of values into two groups. • One set of values which are less likely to occur if the null hypothesis is true. This group constitutes what is known as the rejection region. • The other set of values are those which are more likely to occur if the null hypothesis is true.This group constitutes what is known as the nonrejection region. • Decision rule: • Reject the null hypothesis if the value of the test statistic computed from the sample is a value in the rejection region. • Do not reject the null hypothesis if the value of the test statistic is in the nonrejection region. • Since the value of the test statistic depends on its distribution , the decision rule is a probability statement/probabilistic decision rule. Level of Significance • The level of significance is the probability of rejecting a true null hypothesis. • It specifies the area under the curve of the probability distribution of the test statistic for its values above the rejection region. • Rejecting a true null hypothesis would constitute an error. This is called the type -1 error. This is denoted by α ( alpha ) . Type -1 error has to be a small value. Usually α =0.01,0.05,0.10 • When we fail to reject a null hypothesis , the risk of failing to reject a false null hypothesis is present. • This is an error again!. The error committed when a false null hypothesis is not rejected is called type-2 error. The probability of committing a type-2 error is denoted by β (beta ). • We fix type-1 error at a low level but we have no control over type -2 error. • The following table shows the actions/decisions of a researcher based on the situation reflected by the test hypothesis. Ho True Reject Fail to Reject Type I Error O.K. False O.K Type II Error Calculation of test statistic • Using the sample data we compute the test statistic. This value is compared with the values in the rejection and nonrejection regions. These regions are specified when we fix the type-1 error. • The hypothesis is rejected if the computed value of the test statistic falls in rejection region and it is not rejected if the value falls in the nonrejection region. • If null hypothesis is not rejected it does not mean the null hypothesis is accepted. We should say that the null hypothesis is ” not rejected”. • We avoid using “ accept “ because we might have committed “ type -2 error “. This error could be quite high and hence we do not commit “ acceptance “. What is p-value? • p-value is the probability that tells how unusual our sample results are, given that the null hypothesis is true.It indicates the probability that the sample results are not likely to have occurred, if the null hypothesis is true. • Assuming H0 is true, the probability that the test statistic will take on values as or more extreme than the observed test statistic (computed from the sample data) is called the p-value of the test. • The smaller the P-value, the stronger the evidence against H0. • To take a decision about the null hypothesis,we compare the p-value with the level of significance α. • If p-value is greater than or equal α, we say that the test is “ not significant”. There is not enough evidence to reject the null hypothesis. • If p-value is less than α, we say that the test is “significant”. There is enough evidence to reject the null hypothesis.
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