RNA Sequencing Analysis of Intracranial Aneurysm Walls
Reveals Involvement of Lysosomes and Immunoglobulins
in Rupture
by Rachel Kleinloog, Bon H. Verweij, Pieter van der Vlies, Patrick Deelen, Morris A.
Swertz, Louis de Muynck, Philip Van Damme, Fabrizio Giuliani, Luca Regli, Albert
van der Zwan, Jan W. Berkelbach van der Sprenkel, K. Sen Han, Peter Gosselaar,
Peter C. van Rijen, Emine Korkmaz, Jan A. Post, Gabriel J.E. Rinkel, Jan H. Veldink,
and Ynte M. Ruigrok
Stroke
Volume 47(5):1286-1293
April 25, 2016
Copyright © American Heart Association, Inc. All rights reserved.
Differential expression in aneurysms versus controls visualized in a volcanoplot (A) and a
heatmap (B).
Rachel Kleinloog et al. Stroke. 2016;47:1286-1293
Copyright © American Heart Association, Inc. All rights reserved.
Heatmap showing the differential expression of the 8 genes used in the validation experiment.
Rachel Kleinloog et al. Stroke. 2016;47:1286-1293
Copyright © American Heart Association, Inc. All rights reserved.
Differential expression in ruptured versus unruptured aneurysms visualized in a volcanoplot (A)
and a heatmap (B).
Rachel Kleinloog et al. Stroke. 2016;47:1286-1293
Copyright © American Heart Association, Inc. All rights reserved.