Name _________________________________ Date__________ Period _____ _ Genetics PRACTICE TEST MULTIPLE CHOICE: Circle the answer that best completes the sentence. The different alternatives or choices for a gene (like blue, green, or brown eyes) are called _____________. A. generations B. traits C. tetrads D. alleles Crossing organisms from the F1 generation produces the _____ generation. A. P2 B. F2 C. P1 D. None of these-you can’t cross F1 organisms with each other! Crossing organisms from the P1 generation produces the _____ generation. E. P2 F. F1 G. F2 H. None of these-you can’t cross P1 organisms with each other! Mendel’s “factors” are now called ___________________. A. gametes B. genes C. cells D. zygotes What pattern did Mendel see when crossing pure TALL with pure SHORT pea plants? A. ALL the F1 offspring were short, but the F2 generation were all tall. B. ALL the F1 offspring were tall, but the F2 generation were all short. C. ALL the F1 offspring were short, but 50% the F2 generation were all tall and 50% were short. D. ALL the F1 offspring were tall, but 25% the F2 generation were short and 75% were tall. WHICH OF THE FOLLOWING IS TRUE of MENDELIAN INHERITANCE? A. If a dominant allele is present, the recessive allele won’t be seen. B. If a recessive allele is present, the dominant allele won’t be seen. C. Both recessive and dominant alleles show if present * * * * * * * * * 1 * * * * * * MATCH THE WORD FROM THE WORD BANK WITH ITS DEFINITION: GENETICS HEREDITY TRAIT DOMINANT RECESSIVE ____ TRAIT PURE-BREEDING ALLELE FERTILIZATION ___ A characteristic that can be observed such as hair color, seed shape, flower color, etc ___ FERTILIZATION _____ The joining of a sperm and egg to make a zygote ____ DOMINANT ____ A gene choice that MASKS ANOTHER choice for a trait _____ RECESSIVE _____ A gene choice that IS MASKED BY ANOTHER choice for a trait _____ GENETICS ____ the branch of biology that studies how characteristics are transmitted from parent to offspring _____ HEREDITY ______ the passing of characteristics from parent to offspring _____ ALLELE ______ An alternative choice for a gene (such as brown, green, or blue eyes) ____ PURE-BREEDING ___ An organism that always produces offspring identical to itself if self pollinated * * * * * * * * * * * * * * PUNNETT SQUARE PRACTICE Use a Punnett Square to show the possible offspring from the crosses given and answer the questions: IN PEAS: R = round r=wrinkled T= tall t = short Y = yellow peas P = purple flowers y = green peas p = white flowers MAKING MONOHYBRID CROSSES: What is the genotype of a HOMOZYGOUS YELLOW SEED plant? ______YY________ What is the genotype of A HOMOZYGOUS GREEN SEED plant? _______yy_____________ What is the genotype of a HETEROZYGOUS YELLOW plant? ________Yy_______ 2 Make a cross between a PURE YELLOW SEED parent and a PURE GREEN SEED parent. Genotypes of Parents: Yy Yy Yy Yy ____YY__ X ___yy___ POSSIBLE OFFSPRING GENOTYPES ___Yy______________________________ POSSIBLE OFFSPRING PHENOTYPES ___Yellow_____________________________________ What is the probability an offspring will show the DOMINANT TRAIT (YELLOW SEEDS)? __100__% What is the probability an offspring will show the RECESSIVE TRAIT (GREEN SEEDS)? ___0______% * * * * * * * * * * * * * * What is the genotype of a PURE PURPLE FLOWERED plant ? = _PP_____ What is the genotype of a PURE WHITE FLOWERED plant? = ___pp______ What is the genotype of a HYBRID PURPLE FLOWERED plant? = __Pp___ Make a cross between a HOMOZYGOUS PURPLE FLOWERED plant and a HOMOZYGOUS WHITE FLOWERED plant. Genotypes of Parents: Pp Pp Pp Pp __PP______ X _pp_________ POSSIBLE OFFSPRING GENOTYPES __________ Pp, ______________________ POSSIBLE OFFSPRING PHENOTYPES _____purple, _______________________________ 3 What is the probability an offspring will show the DOMINANT TRAIT (PURPLE FLOWERS)? __________100_______________% What is the probability an offspring will show the RECESSIVE TRAIT (WHITE FLOWERS)? ____________0________________% SEE A PATTERN FOR HOMOZYGOUS (P1) MONOHYBRID CROSSES: If you cross plants that are PURE DOMINANT for a trait with plants that are PURE RECESSIVE for that trait, __100______ % of the offspring will show the DOMINANT trait and the ___recessive________________ trait will not show at all. USE THE PATTERN ABOVE TO MAKE PREDICTION ABOUT A CROSS If you cross a HOMOZYGOUS ROUND SEED plant with a PURE WRINKLED SEED plant 100% will look _____round_____________ 0% will look _______wrinkled_____________ The offspring will have a 100% probability of having the __Rr____ genotype. * * * * * * * * * * * * MAKE SOME HETEROZYGOUS MONOHYBRID CROSSES A black coat (B) is DOMINANT in guinea pigs. A brown coat (b) is RECESSIVE. What is the genotype of a HOMOZYGOUS BLACK guinea pig? = ___BB____ What is the GENOTYPE of a HETEROZYGOUS BLACK guinea pig? =___Bb______ What is the GENOTYPE of a brown guinea pig? =_____bb_____ 4 * * Make a cross between TWO HETEROZYGOUS BLACK guinea pigs. Genotypes of Parents: BB Bb Bb bb ____Bb______ X ____Bb______ POSSIBLE OFFSPRING GENOTYPES _____BB, Bb, bb___________________________________ POSSIBLE OFFSPRING PHENOTYPES ____Black, browm__________________________________ What is the probability that a baby will be black? ____75_____ % What is the probability that a baby will be brown? ____25_____% What is the probability the baby will be a HYBRID? ____50____% What is the probability the baby will be HOMOZYGOUS DOMINANT ? ___25______% What is the probability the baby will be HOMOZYGOUS RECESSIVE? ____25_______% * * * * * * * * * * * * * * Purple fur (P) is DOMINANT in monsters. Yellow fur (p) is RECESSIVE. What is the genotype of a PURE PURPLE monster? __PP______ What is the GENOTYPE of a HETEROZYGOUS purple monster? __Pp__ What is the GENOTYPE of a YELLOW monster? ____pp____ Make a cross between TWO HETEROZYGOUS PURPLE MONSTERS. Genotypes of Parents: PP Pp Pp pp _____Pp_____ X ___Pp_______ 5 POSSIBLE OFFSPRING GENOTYPES ____________ PP, Pp, pp_____________ POSSIBLE OFFSPRING PHENOTYPES ____________Purple, yellow_________________________ What is the probability that a baby will be purple? ______75____% What is the probability that a baby will be yellow? _____25_____% What is the probability the baby will be a heterozygous? ____50___% What is the probability the baby will be HOMOZYGOUS DOMINANT ? _25________% What is the probability the baby will be HOMOZYGOUS RECESSIVE? ____25_______% SEE A PATTERN FOR HETEROZYGOUS (F1) MONOHYBRID CROSSES: If you cross 2 parent plants that are BOTH HETEROZYGOUS for a trait the offspring will show a __3__ : __1__ phenotypic ratio. _75_______ % of the offspring will show the DOMINANT trait and ___25_____ % of the offspring will show the RECESSIVE trait. USE DOMINANT OR RECESSIVE TO FILL IN THE BLANKS BELOW: ¼ of the offspring will have two ____dominant______________ alleles, ½ will be hybrids with one _____ dominant ____ and one ______recessive_________ allele, and ¼ will have two ______ recessive ___________ alleles. USE THE PATTERN ABOVE TO MAKE PREDICTION ABOUT A CROSS If you cross two HETEROZYGOUS ROUND SEED plants 75% will look ____round______________ 25% will look _______wrinkled___________ The probability is: ¼ will have the genotype __RR____ genotype __rr___ ½ will have the genotype __Rr___ 6 ¼ will have the * * * * * * * * * * * * * * Scientists have been investigating the genetic make up of the residents in Bikini Bottom. Complete the following questions about these inhabitants. For each genotype below, indicate whether it is HETEROZYGOUS (HE) or HOMOZYGOUS (HO). TT ___Ho Bb __He DD ___ Ho tt ____ Ho Ff ____ He Dd _____ He ff ____ Ho bb ____ Ho BB ____ Ho FF __ Ho _ Determine the PHENOTYPE for each genotype given. IN SPONGE PEOPLE the allele for YELLOW BODY COLOR (Y) is DOMINANT to BLUE (y). YY = ____yellow____ Yy = _____ yellow _____ yy = ___blue_________ IN SPONGEPEOPLE the allele for SQUARE SHAPE (S) is dominant to ROUND (s). SS = ___square_______ Ss = ____square_______ * * * * * * * * * * * ss = _____round_______ * * * * SpongeBob SquarePants recently met SpongeSuzie RoundPants at a dance. SpongeBob is HETEROZYGOUS for his square pants, but Suzie is ROUND. Create a Punnett square to show the possibilities that could result if SpongeBob and SpongeSuzie had children. Genotypes of Parents: ____Ss______ X _____ss_____ What is SpongBob’s genotype? ___Ss__________ What is SpongeSuzie’s genotype? ____ss_______ What are the chances a child will have a square shape? __2______ out of 4 OR ___50____% What are the chances a child will have a round shape? ___2_____ out of 4 OR _50______% * * * * * * * * * * * * * * In SQUID PEOPLE the allele for LIGHT BLUE SKIN (B) is DOMINANT over the GREEN (b) allele. Everyone in SquidWard’s family has light blue skin. His family brags that they are a “purebred” line. He recently married a nice girl with light green skin, which is recessive. Create a Punnett square to show the possible offspring from this match. 7 Genotypes of Parents: _____BB_____ X ____bb______ POSSIBLE OFFSPRING GENOTYPES ___Bb_____________________________________ POSSIBLE OFFSPRING PHENOTYPES __Blue______________________________________ What are the chances of a child with green skin? ___0___% Would SquidWard’s children still be considered “purebreds”? YES NO EXPLAIN WHY or WHY NOT. ______No, they are heterozygous Bb, not homozygous (pure) _____________________________________________________________________ _____________________________________________________________________ * * * * * * INCOMPLETE DOMINANCE: * * * * * * * * In Four O’clock plants RED FLOWERS (FR) are INCOMPLETELY dominant over white (FW) flowers. Heterozygous plants show a blended intermediate phenotype of PINK flowers. MAKE A CROSS WITH 2 HETEROZYGOUS FOUR O’CLOCK PLANTS. Genotypes of Parents: ___ FR FW _______ X ____ FR FW ______ Genotypes____ FR FR ____ FR FW __ FW FW ___ Genotypic Ratio _1:2:1_____________________ Phenotypes __red, pink, white______________ Phenotypic Ratios _1:2:1____________________ IF the red allele in Four-o’clocks WAS COMPLETELY DOMINANT over the white allele, what would the phenotype be for a plant with Rr genotype? __________red__________ * * * * * * * * * 8 * * * * * * You are exploring the jungle and find a new species of plant. Some of the plants have red flowers and some have yellow flowers. You cross a red flowering plant with a yellow flowering plant and all the offspring have orange flowers. You might assume that the alleles for flower color in this plant show ____________________. A. complete dominance B. incomplete dominance C. codominance If the red and yellow alleles in the mystery jungle plant above showed CODOMINANCE instead, what might you expect a plant with one red allele and one yellow allele to look like? A. B. C. D. It would have all red flowers It would have all blue flowers It would have red and yellow flowers together on one plant It wouldn’t make any flowers because it is a mutant. BLOOD TYPES: In the ABO blood type system the A and B alleles are dominant to O allele, and A and B are codominant to each other. Make a cross between a type A (heterozygous) mom and a type B (heterozygous) dad. IAi x IBi What are the possible genotypes of the offspring? __IAIB______ ___IA_i_____ ___IB_i_____ ____ii_____ What is the probability the offspring will have: A type blood _25___% B type blood __252___% O type blood _25____% AB type blood ___25____% * * * * * * * * * 9 * * * * * * Make a cross between a type A (heterozygous) mom and a type B (homozygous) dad. IAi x IBIB What are the possible genotypes of the offspring? ___ IAIB _____ ___ IAIB ______ ___ IB_i ______ ____ IB_i _____ What is the probability the offspring will have: A type blood __0___% B type blood ____50__% O type blood ___0__% AB type blood ___50___% * * * * * * * * * * * * * * * Make a cross between type A (homozygous) mom and a type O dad. IAIA x ii What are the possible genotypes of the offspring? ___IA_i____ ___ IA_i ___ __ IA_i ___ ___ IA_i ____ What is the probability the offspring will have: A type blood ___100_% B type blood ___0__% O type blood ____0_% AB type blood ___0___% * * * * * * * * * * * * * * * You are working in the Emergency room and a bleeding patient with type B blood is brought in. You need to give him blood, but the hospital is all out of type B. Circle ALL the types of blood could you safely give him instead. 10 A AB O EXPLAIN your choices. __Type B makes anti-a antibodies, so cannot give him blood with A antigen______________________________________________________ What if the bleeding patient had type AB blood and the hospital was out of AB blood. Circle ALL the types of blood could you safely give him. A B O EXPLAIN your choices. Type AB has A and B antigens and makes no antibodies, so can receive all JERRY SPRINGER GENETICS: Wanda tells Jerry Springer that she thinks either Ralph or Fred could be the father of her baby. Wanda’s genotype is IAi. Wanda’s baby has type O blood. Ralph’s is type AB. Fred’s genotype is IBi. Make two crosses to show who could be the father of Wanda’s baby. Ralph X Wanda IA Fred X Wanda i IA i IA IAIA IAi IB IAIB IBi IB IAIB IBi I IAi ii Is it possible for Ralph to be the baby’s father? YES Is it possible for Fred to be the baby’s father? YES NO NO Does this absolutely PROVE that Fred IS the baby’s father? EXPLAIN YOUR ANSWER. 11 YES NO ___This just means that Fred has the same blood type as the baby ___________________________________________________________ ___________________________________________________________ IF Wanda’s baby has type O blood, what are the possible genotypes for men who COULD BE the father of Wanda’s baby? _____IAi, IBi, ii_________________________________________ * * * * * * * * * * * * * * * IN PEAS: R = round T= tall Y = yellow peas r = wrinkled t = short y = green peas P = purple flowers p = white flowers MAKING HOMOZYGOUS DIHYBRID CROSSES: Cross a HOMOZYGOUS TALL, HOMOZYGOUS ROUND pea with a SHORT, WRINKLED pea. Parent's genotypes _TTRR_________ X ___ttrr_______ Possible gametes _TR_ _TR_ _TR_ _TR_ _tr__ _tr_ _tr__ tr__ How many out of 16 will be: ____16___ TALL & ROUND _____0__ TALL & WRINKLED _____0__ SHORT & ROUND _____0__ SHORT & WRINKLED 12 * * * * * * * * * * * * * * * * * * * * * * * * * * * * SEE A PATTERN FOR HOMOZYGOUS (P1) DIHYBRID CROSSES: * * If you cross plants that are PURE DOMINANT for TWO TRAITS with plants that are PURE RECESSIVE for TWO TRAITS, ___100_____ % of the offspring will look DOMINANT for BOTH traits and the _____recessive___________ traits will not show at all. * * * * * * * * * * * * * * * Cross a HETEROZGOUS TALL, HETEROZYGOUS ROUND pea with a PURE SHORT, WRINKLED pea. Parent's genotypes ___TtRr_______ X _____ttrr_____ Possible gametes _TR_ _Tr _tR_ _tr_ _tr_ _tr_ _tr__ _tr_ How many out of 16 will be: ___4____ TALL ROUND ___4____ TALL WRINKLED ___4____ SHORT ROUND ___4___ SHORT WRINKLED 13 * * * * * * * * * * * * * * * FIND THE PATTERN FOR HETEROZYGOUS (F1) DIHYBRID CROSSES: If you cross 2 parent plants that are BOTH HETEROZYGOUS for TWO TRAITS, the offspring will show a _9___ : __3__ : _3___ : __1__ phenotypic pattern. Fill in the blanks below with: DOMINANT or RECESSIVE 9/16 of the offspring will show both ____ DOMINANT _______________ traits. 3/16 will look _____ DOMINANT ____________ for trait 1 and ___________ RECESSIVE ______ for trait 2. 3/16 will look _________ RECESSIVE _________ for trait 1 and _____ DOMINANT ____________ for trait 2. 1/16 will look _______ RECESSIVE _____________ for both traits. USE THIS PATTERN TO TELL THE POSSIBLE OFFSPRING OF A HETEROZYGOUS DIHYBRID CROSS WITHOUT USING A PUNNETT SQUARE: R = round r=wrinkled RrTt T= tall t = short X RrTt 9/16 will look _____round ___________ and _______tall________ 3/16 will look _____round___________ and _______short__________ 3/16 will look _____wrinkled__________ and ______tall_________ 1/16 will look _____wrinkled____________ and ____short______________ 14 Rhett and Scarlett are expecting a baby. Rhett’s rich uncle has promised them $1 million if their baby is a blue eyed boy that can carry on the family name. Brown eyes (B) are dominant over blue eyes (b). Rhett is heterozygous for brown eyes, while Scarlett has blue eyes. Fill in the Punnett square with Rhett and Scarlett’s possible gametes. Rhett’s Genotype: __BbXY___ Scarlett’s Genotype: _bbXX_____ Possible gametes: _BX__ __BY__ __bX__ _bY___ __bX__ _bX_ ___bX_ _bX__ What genotype does a baby need to be a blue eyed boy and get the $1 million? ____bbXY____ Use a Punnett square to show the possible genotypes for their baby. ___4____ Brown eyed boys __4_____ Brown eyed girls ___4____ Blue eyed girls ___4____ Blue eyed boys What is the probability they will have a BLUE-EYED BOY and get the $1 million? ____25______% Why does this cross not follow the 9:3:3:1 pattern for DIHYBRID (2 gene) crosses? Not 2 parents that are both dihybrid for 2 traits 15 LINKAGE A boy, whose parents and grandparents had normal vision, is color-blind. What are the genotypes for his mother and his maternal grandparents. Use XB for the dominant normal condition and Xb for the recessive, color-blind phenotype. XBXb Xb XBXb Xb XbY The bison herd on Konza Prairie has begun to show a genetic defect. Some of the males have a condition known as "rabbit hock" in which the knee of the back leg is malformed slightly. We do not yet know the genes controlling this trait but for the sake of our question, we shall assume it is a sex-linked gene and that it is recessive. Now, suppose that the herd bull (the dominant one which does most of the breeding) who is normal (XN) mates with a cow that is a carrier for rabbit hock. What are his chances of producing a normal son? X NY x X N X n XN Xn XN XN XN Xn Y XN Y Xn Y 25% chance In humans the gene from normal blood clotting, H, is dominate to the gene for hemophilia, h. This is a sex-linked trait found on the X chromosome. A woman with normal blood clotting has four children. They are a normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is the probable genotype for each member of the family? 16 woman with normal blood clotting XN Xn father has normal blood clotting XN Y normal son XN Y hemophiliac son Xn Y two normal daughters XN XN or XN Xn XN Y XN XN XN XN Y Xn XN Xn Xn Y 10.3.1 Define polygenic inheritance. 10.3.2 Explain that polygenic inheritance can contribute to continuous variation using two examples, one of which must be human skin colour. Modified from: http://brookings.k12.sd.us/biology 17
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