Immediate Function in extraction
sites – proven concept with high
patient satisfaction.
Science First
Better soft tissue results
Immediate Function of implants placed in extraction sites is
a proven concept with predictable outcomes for implants
with TiUnite surface. It has the potential to improve esthetic
results and increase patient satisfaction.1 In addition, it
shortens healing times, decreases the number of required
appointments and reduces costs.
Immediate placement combined with Immediate Function has a
positive effect not only on marginal bone levels, but also esthetics,9–12
since immediate restoration preserves pink esthetics.11,12 If primary
implant stability permits, implants should therefore be instantly
provisionalized in the interest of optimal soft tissue esthetics.12
Survival rates comparable to healed sites
High patient satisfaction
Long-term studies with 5 to 10 years follow-up show cumulative
survival rates (CSR) of 96.5% to 100% for immediately loaded
implants placed in extraction sites for any indication.2,3,4 No
statistically significant differences could be observed in prospective
studies with >1 year follow-up on TiUnite implants in fresh extraction
versus healed sites.3,5,6
Significant improvements in patient self-ratings of self-esteem,
function, esthetics, sense and speech, right after implant insertion
and at delivery of the final prosthesis.1,13
Stable or increasing marginal bone levels
Minimal marginal bone change after implant insertion followed by
stable or increasing bone levels.1,2,4,8
Studies with tapered implants such as NobelActive,1,11
NobelReplace10,12 and Replace Select 2,8,11 show excellent results
with regards to CSR, marginal bone levels, esthetics and patient
satisfaction.
Better soft tissue levels
Immediate loading helps support papilla and
midfacial mucosa levels.
0.4
Change of mucosa levels (mm)
Marginalbone
bonelevel
levelchange
change(mm)
(mm)
Marginal
Stable or increasing bone levels
Implants immediately loaded in extraction sites with the
radiographic baseline set at time of insertion. Therefore,
all bone remodeling is reported.
Choice of implant type may be important for successful results
0.2
0
-0.2
-0.4
-0.6
-0.8
-1.0
0
12
Time
after
implantation(months)
(months)
Time
after
implantation
24
0.0
-0.2
Immediate
loading
Delayed
loading
-0.4
-0.6
-0.8
-1.0
36*
Minimal marginal bone change after implant insertion followed by stable
or increasing bone levels (*not significant).1
0246810
12
Time after implantation (months)
Immediate provisionalization limits midfacial soft tissue loss during the first year
after implant placement compared to delayed loading.11
Published clinical studies confirm the reliable performance of TiUnite implants with Immediate Function in extraction sites.
They include 1275 TiUnite implants in nearly 620 patients in various indications, with follow-up times of up to 10 years.
References
1 Kolinski ML, Cherry JE,
McAllister BS, Parrish KD,
Pumphrey DW, Schroering RL.
Evaluation of a Variable-Thread
Tapered Implant in Extraction Sites
With Immediate Temporization: A
3-Year Multi-Center Clinical Study. J
Periodontol 2014;85:386-94
6 Weinstein R, Agliardi E, Fabbro
MD, Romeo D, Francetti L.
Immediate rehabilitation of the
extremely atrophic mandible with
fixed full-prosthesis supported by
four implants. Clin Implant Dent
Relat Res 2012;14:434-41
10 Cosyn J, Eghbali A, De Bruyn H,
Collys K, Cleymaet R, De Rouck T.
Immediate single-tooth implants in
the anterior maxilla: 3-year results of
a case series on hard and soft tissue
response and aesthetics. J Clin
Periodontol 2011;38:746-53
2 Mura P. Immediate Loading of
Tapered Implants Placed in
Postextraction Sockets: Retrospective Analysis of the 5-Year Clinical
Outcome. Clin Implant Dent Relat
Res 2012;14:565-74
7 Mozzati M, Arata V, Gallesio G,
Mussano F, Carossa S. Immediate
Postextractive Dental Implant
Placement with Immediate Loading
on Four Implants for MandibularFull-Arch Rehabilitation: A
Retrospective Analysis. Clin Implant
Dent Relat Res 2013;15:332-40
11 Cosyn J, De Bruyn H, Cleymaet
R. Soft Tissue Preservation and Pink
Aesthetics around Single Immediate
Implant Restorations: A 1-Year
Prospective Study. Clin Implant Dent
Relat Res 2013;15:847–57
3 Degidi M, Nardi D, Piattelli A.
­10-Year Follow-Up of Immediately
Loaded Implants with TiUnite
Porous Anodized Surface. Clin
Implant Dent Relat Res 2012 [epub
ahead of print]
4 Polizzi G, Cantoni T. Five-Year
Follow-Up of Immediate Fixed
Restorations of Maxillary Implants
Inserted in Both Fresh Extraction
and Healed Sites Using the
NobelGuide™ System. Clin Implant
Dent Relat Res 2013 [epub
ahead of print]
5 Malo P, Nobre Mde A, Lopes A.
Immediate Rehabilitation of
Completely Edentulous Arches with
a Four-Implant Prosthesis Concept
in Difficult Conditions: An Open
Cohort Study with a Mean
Follow-up of 2 Years. Int J Oral
Maxillofac Implants 2012;27:1177-90
For more scientific evidence visit
nobelbiocare.com/scientific-evidence
8 Hartlev J, Kohberg P, Ahlmann
S, Gotfredsen E, Andersen NT, Isidor
F, Schou S. Immediate placement
and provisionalization of
single-tooth implants involving a
definitive individual abutment: a
clinical and radiographic
retrospective study. Clin Oral
Implants Res 2013;24:652-58
9 Esposito M, Grusovin MG,
Polyzos IP, Felice P, Worthington HV.
Interventions for replacing missing
teeth: dental implants in fresh
extraction sockets (immediate,
immediate-delayed and delayed
implants). Cochrane Database Syst
Rev 2010:CD005968
12 De Rouck T, Collys K, Wyn I,
Cosyn J. Instant provisionalization of
immediate single-tooth implants is
essential to optimize esthetic
treatment outcome. Clin Oral
Implants Res 2009;20:566-70
13 Hartlev J, Kohberg P, Ahlmann
S, Andersen NT, Schou S, Isidor F.
Patient satisfaction and esthetic
outcome after immediate placement
and provisionalization of
single-tooth implants involving a
definitive individual abutment. Clin
Oral Implants Res 2013 [epub ahead
of print]
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Clinical evidence on Immediate
Function in extraction sites.