Bayesian Networks as Clinical Decision Support Systems in Medical Settings: A Review Health managers and clinicians are frequently asked to provide quantifiable information to support their decision, which is not always easy to obtain. Therefore, some artificial intelligence systems are idealized to support healthcare professionals with responsibility based on the manipulation of information and knowledge. Bayesian can be used to are represent the These Clinical Decisionnetworks Support Systems (CDSS) considered probabilistic and interdependencies a set an of to combine relationships medical knowledge base, patient among data and variables, engine namelyto diseases and symptoms. inference generate case specific advice.[2] (Classen, 1998) Medical Knowledge Patient Data Advice Artificial Intelligence System (such as Bayesian Networks) In which healthcare domains and clinical fields are Bayesian networks being used as clinical decision support systems in Medicine? Identify the healthcare domains and point out which fields (diagnosis, therapy and prognosis) are usually targeted by BN as CDSS in real-world clinical practice. Discuss the efficacy, effectiveness and efficiency of BN in CDSS expressed in the included studies. Review: The opinions by a review third reviewer and the The divergent articles/papers usedarein solved systematic are searched in exclusion are of registered. It isand necessary evaluate this Medline, causes ISI Web Knowledge Scopus.toThis literature process’ anda toconjunction register the of exclusion motives. search isreproducibility conducted by keywords (and their synonyms) with other words related with variables. Finally, a specific formulary is created for data extraction and processed using SPSS. keywords: - Decision Support Systems, Clinical - Bayes Theorem possible, a meta-analysis will be If applied. The final results are interpreted, discussed and the final article is elaborated. All the articles are collected using EndNote and are reviewed by two peers. Initially, these two reviewers analyze the title and the abstract, registering briefly the causes of non-selection. Then, the chosen articles are read integrally and are applied the inclusion and exclusion criteria, previously elaborated. Types of Study (e.g. Experimental vs observational) and Data types (primary data vs secondary data) Articles’ information (First author’s country affiliation, publication date, institution) Healthcare domains (emergency, critical care, stroke service…) Clinical fields (diagnosis, therapy, prognosis) Efficacy, techniques Effectiveness and Efficiency of Bayesian’s Inclusion Criteria: Applied to diagnosis or prognosis or therapeutic related to Bayes theorem Include results Paper provides details so that the study can be reproduced Written in English Exclusion Criteria: Meta-analysis and reviews Not applied to humans Most of the articles found refer to Diagnostic tests of CDSS based on BN. CDSS based on BN are more frequently used in diagnosis. CDSS based on BN have been applied in Rapid Assessment Unit and in Emergency. CDSS based on BN are efficacious and effective but not efficient. Start 1. 2. 3. 4. 5. 6. 7. Tan J, Sheps S (1998). Health Decision Support Systems. Jones & Bartlett Publishers. Classen DC. Clinical decision support systems to improve clinical practice and quality of care. JAMA. 1998 Oct 21;280(15):1360-1. Coiera E (2003). The Guide to Health Informatics (2nd Edition). Arnold, London. Sim I, Sanders GD, McDonald KM. Evidence-based practice for mere mortals: the role of informatics and health services research. J Gen Intern Med. 2002 Apr;17(4):302-8. Fieschi M, Dufour JC, Staccini P, Gouvernet J, Bouhaddou O. Medical decision support systems: old dilemmas and new paradigms? Methods Inf Med. 2003;42(3):190-8. Erratum in: Methods Inf Med. 2003;42(4):VI. Miller RA. Medical diagnostic decision support systems--past, present, and future: a threaded bibliography and brief commentary. J Am Med Inform Assoc. 1994 Jan-Feb;1(1):8-27. Erratum in: J Am Med Inform Assoc. 1994 Mar-Apr;1(2):160. Wong HJ, Legnini MW, Whitmore HH. The diffusion of decision support systems in healthcare: are we there yet? J Healthc Manag. 2000 Jul-Aug;45(4):240-9; discussion 249-53.
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