Prognostic factors and scoring systems in chronic
myelomonocytic leukemia: a retrospective analysis of 213
patients
by Francesco Onida, Hagop M. Kantarjian, Terry L. Smith, Greg Ball, Michael J.
Keating, Elihu H. Estey, Armand B. Glassman, Maher Albitar, Monica I. Kwari, and
Miloslav Beran
Blood
Volume 99(3):840-849
February 1, 2002
©2002 by American Society of Hematology
Kaplan-Meier survival curve of CMML patients.Overall survival of all 213 patients with CMML
(dotted lines denote 95% CI).
Francesco Onida et al. Blood 2002;99:840-849
©2002 by American Society of Hematology
Kaplan-Meier survival curves of CMML patients grouped according to patient characteristics
identified by univariate analysis.Survival curves for patients grouped by (A) WBC counts (≤ or
> 13 × 109/L); (B) hemoglobin (HGB) level (≥ or < 120 g/L [12 g/dL]); (...
Francesco Onida et al. Blood 2002;99:840-849
©2002 by American Society of Hematology
CART survival model.This model identified the presence of peripheral blood IMCs as the
strongest independent variable determining shorter survival, followed by the absolute
lymphocyte count above 1.9 × 109/L and the hemoglobin level below 119 g/dL (11.9 g/d...
Francesco Onida et al. Blood 2002;99:840-849
©2002 by American Society of Hematology
Kaplan-Meier survival curves of CMML patients according to their risk classification by
MDAPS.A total of 213 patients had a diagnosis of CMML; 23 patients had some missing data,
which did not allow assignment of a definite score according to risk factors.
Francesco Onida et al. Blood 2002;99:840-849
©2002 by American Society of Hematology