DEPARTMENT OF STATIS TICS COLLEGE OF ARTS & SCIENCES 330.972.6886 (TELEPHONE) Course Description 3470:473/573 Survival Analysis 3 credits Prerequisite: 3470:461/561 Applied Statistics or equivalent. Course Description: Basic concepts in survival analysis, censoring and data truncation, estimation of survival models, nonparametric hazard and survival function estimation, comparing survival times between groups. Course Topics: Introduction to Survival Analysis. Definitions and examples of survival and hazard functions and the relationship between them. Common parametric models for survival data. Censoring and truncation, likelihood construction, and the development of maximum likelihood. Nonparametric inferences for survival and hazard functions based on single sample data, Kaplan-Meier estimate, Nelson Aalen estimate. Nonparametric methods for testing equality of survival/hazard curves. Computer assisted analysis of survival data. Continuous and discrete-time regression models with emphasis on Cox's proportional hazards model and partial likelihood estimation. Computer package implementation of the analysis of survival data. Methods for determining parametric and nonparametric model adequacy, including calculation of various kinds of residuals, determination of various plotting techniques, embedding a selected model into a larger model for testing. Regression diagnostics. Fall 2014
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