1 CURRICULUM VITAE OF DAVID GORDON, MD 2014-2015 Rank: Professor Area of Responsibility: Dean, College of Health Professions, University of Akron Date of Initial Appointment: October 31, 2014 Date of Appointment to Current Rank: October 31, 2014 License Numbers: 1980 Washington 1992 Michigan Certifications: Board 1985 Anatomic Pathology Graduate Faculty Status: Pending EDUCATION Sept. 1967- June 1969 June 1969 – Sept. 1969 Sept. 1969- May 1973 May 1973-Sept 1973 Sept. 1973- June 1979 Northwood High School, Silver Spring, MD Summer employment (Mrs. Kay’s Toll House, Silver Spring, MD) Amherst College, Amherst, MA, A.B. (summa cum laude) Summer employment (Natl. Oceanic Atmospheric Admin., Silver Spring, MD) Harvard Medical School, Boston, MA, M.D. (cum laude) POSTDOCTORAL TRAINING & FELLOWSHIPS Dec. 1, 1977- Nov. 30, 1979 Medical Student Research Fellowship with Morris J. Karnovsky, Harvard Medical School, Boston, MA (Vessel wall biology in rat models of intimal thickening) July 1, 1979- June 29, 1980 Internship in Internal Medicine, University of Massachusetts Medical Center, Worchester, MA July 1, 1980- Mar. 1985 Residency in Pathology, University of Washington School of Medicine, Seattle, WA July 1, 1981-June 30, 1984 Postdoctoral Research Fellowship, Department of Pathology, University of Washington School of Medicine, Seattle, WA 1 2 EXECUTIVE EDUCATION (Courses/Seminars) 2000 Univ. of Michigan Business School Executive Education Center: “Fundamentals of Leadership.” 2002 Harvard Univ. Program on Negotiation: “Teaching Negotiation in the Organization” April 7-9. Essentials for Leading a Diverse Workforce (diversity training course given by UMHS Human Resources. I also served as a facilitator for other such courses) 2003 2004-2005 Univ. of Michigan Health System Leadership Development Program 2004, 2008 AAMC Executive Development Seminar for Associate Deans and Dept. Chairs. 2006 The Masters Series Leadership Course (given by UMHS Human Resources June 12-16, 2006) ACADEMIC APPOINTMENTS Mar. 1, 1985- July 1, 1991 Assistant Professor of Pathology, Department of Pathology, University of Washington School of Medicine, Seattle, WA July 1, 1991- Nov. 15, 1991 Associate Professor of Pathology (with tenure), Department of Pathology, University of Washington School of Medicine, Seattle, WA Dec. 1, 1991-Nov. 16, 1997 Associate Professor of Pathology, Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI (Received tenure 1997) Nov. 16, 1997- Jan. 31, 2001 Adjunct Associate Professor of Pathology, Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI (Note: during this time I was a research fellow with Pfizer Global Research and Development, Ann Arbor, MI.) Feb. 1, 2001- Oct. 31, 2014 Oct. 31, 2014 – present Professor of Pathology (with tenure), Dept. of Pathology, Univ. of Michigan School of Medicine, Ann Arbor, MI Professor (Active Emeritus) of Pathology (with tenure), Dept. of Pathology, Univ. of Michigan School of Medicine, Ann Arbor, MI OTHER WORK EXPERIENCE: Nov. 16, 1997- Jan. 31, 2001 Research Fellow, Pfizer Global Research and Development (Preclinical Cardiovascular Division), Ann Arbor, MI. Note: My employment here was originally with Parke-Davis Inc. which was later taken over by Pfizer Inc. 2 3 ACADEMIC ADMINISTRATIVE APPOINTMENTS Mar. 1, 1985- Nov. 15, 1991 Director of Autopsy Service, Univ. of Washington, Univ. Hospital Aug. 1, 1994 - Nov. 16, 1997 Assistant Dean for Faculty Affairs, University of Michigan, Ann Arbor, MI. July 1, 1996- Nov. 16, 1997 Associate Director, Jobst Vascular Research Laboratory, Div. of Vascular Surgery, University of Michigan, Ann Arbor, MI Feb.1, 2001 - Mar. 31, 2004 Assistant Dean for Diversity and Career Development. University of Michigan, Ann Arbor, MI April 1, 2004-2011 Associate Dean for Diversity and Career Development, University of Michigan, Ann Arbor, MI Aug. 16, 2011- Oct. 31, 2014 Dean, School of Health Professions and Studies, University of Michigan-Flint, Flint, MI Oct. 31, 2014 – present Dean, College of Health Professions, University of Akron, Akron, Ohio DEAN’S OFFICE RELATED DUTIES: 2001-2011 2002-2011 2002- 2011 2002-2011 2002-2009 2003-2011 20002-2011 2004 2005 2004-2009 2005 2005 2005-2006 2006 2006-2011 2006-2011 2006-2011 2006-2007 2007 2007-2009 2007-2009 2007-2011 2009-2011 2009-2010 Medical School Admissions Executive Committee Director: Medical School Diversity and Career Development Office Director: Minority Health Research Program Member: Univ. of Michigan Health System Diversity Advisory Team Steering Committee Director, Health Occupations Partners in Education (HOPE) program (a health professions schools program mentoring Ypsilanti middle and high school students towards the health professions). Member: Univ. of Michigan Diversity Council (Chair December 2004 – June 2007) Member Univ. of Michigan Medical School K30/K12 Clinical Research Training Grant Advisory Board. Participant Univ. of Michigan Provost seminar and workshop: Transformative Pedagogy in a Contested World Multicultural Pedagogy Workshop Participant (May 23, 2005) Member: Univ. of Michigan National Center for Institutional Diversity Steering Committee and regular committee. Planner, moderator and participant: Futuring Diversity Conference (May 17-18, 2005) Member: Search Committee for new head of Organizational Effectiveness, UMHS Human Resources Member: Search Committee for new CEO of University of Michigan Hospital and Health Services. Member: Search Committee for new Assoc. Dean for Student Programs (U. of M.) Member Univ. of Michigan Health System Leadership Advisory Group Member of the Leadership Competencies Subcommittee (Leadership Advisory Group) Co-chair of the Succession Planning Subcommittee (Leadership Advisory Group) Member and functional chair of the Medical School Taskforce on Team Science/Scholarship Member, Univ. of Michigan Diversity Blueprints Taskforce Member, Community Health Initiative Committee (Faculty Group Practice subcommittee to look at community benefits from our Health System). Member, Univ. of Michigan Health System Community Benefits Report Committee Medical School Lead for Faculty and Staff Leadership Development Programs. Member, Michigan Institute for Clinical and Health Research (MICHR) Education Admissions Committee Vice-Chair, Univ. of Michigan Human Resources Advisory Group 3 4 2010-2011 2011-2014 2011- 2014 2012-2014 2012-2014 2012-2014 2012 2012-2014 2013-2014 2013-2014 2014 2014 – present Chair, Univ. of Michigan Human Resources Advisory Group Member, Greater Flint Health Coalition Board of Directors Member Michigan Health Council (non-voting member 2011-2014, voting member of their Board of Trustees, 2014 Member, Genesee Health Plan Board of Directors Member, Universal Kidney Foundation Advisory Board Member, Univ. of Michigan MHealthy Advisory Board Michigan State University’s College of Human Medicine’s Milestones Curriculum Project (designing a new curriculum for Flint students) Attendee of the Ann Arbor Veterans Administration Hospital’s Affiliation Partnership Council Attendee of the Saginaw Veterans Administration Hospital’s Academic Affiliation Committee Director, University of Michigan-Flint Social Justice Center (planning) Member, Board of Directors for the Hamilton Community Health Network (a Federally Qualified Health Center in Flint, Michigan) Member, Institute for Healthcare Improvement (IHI) Leadership Alliance of Akron COMMUNITY SERVICE/VOLUNTEERING 2012-2013 2013 Participant, Leadership Genesee Program (Community orientation to Genesee County) Volunteer, Hamilton Community Health Network (Federally Qualified Health Center in Flint) CLINICAL/HOSPITAL APPOINTMENTS 1985-91 1992-present 1991- 2011 Staff physician, University of Washington School of Medicine, Seattle, WA. Staff physician, University of Michigan Health System, Dept. of Pathology, Ann Arbor, MI. Member, Cardiovascular Research Institute, University of Michigan, Ann Arbor, MI CONSULTING POSITIONS 1987-1990 1990 1991-1997 1995 2001-2002 Cardiovascular pathology consultant for Genentech, Inc., San Francisco, CA Cardiovascular pathology consultant for Lilly Research Laboratories, Indianapolis, IN Cardiovascular pathology consultant for Parke-Davis Inc., Ann Arbor, MI Consultant for Gladstone Institute of Cardiovascular Disease, San Francisco, CA Consultant for GenVec Inc. (gene therapy biotechnology company). SCIENTIFIC POSITIONS IN INDUSTRY i) 1997-2001 Research Fellow, Department of Vascular and Cardiac Diseases, Parke-Davis Pharmaceutical Research, Ann Arbor, MI (became part of Pfizer, Inc.). Note: Led a therapeutic angiogenesis discovery team to identify adenoviral mediated gene transfer methods to grow new blood vessels for people with coronary and peripheral vascular disease. 4 5 SCIENTIFIC ACTIVITIES Grant Review Committees 1989 1990 1991 1992 1992-1995 1992-1995 1993-1995 1994 1994 1995-1998 2005 Ad Hoc American Heart Association of Los Angeles, CA NHLBI Ad Hoc Special Review of Wissler PDAY Renewal NHLBI Ad Hoc Review Committee, Duke University Prog. Proj. NHLBI Ad Hoc Review Committee, New England Deaconess, Boston, MA American Heart Association (National) (Grant-In-Aid Committee) American Heart Association (National) (Fellowship Committee) American Heart Association of Michigan (Grant-In-Aid Committee) NIH Minority Fellowship Review Committee (NHLBI) Ad hoc reviewer for NIH Pathology A Study Section. Member NIH Pathology A Study Section Ad hoc reviewer for NIH Hemostasis & Thrombosis Study Section Other National Committees: 2001-2005 National Academy of Sciences Committee for “Assessment for NIH Minority Research Training Programs Phase 3” GRANT SUPPORT Past: 1122.RFP.PD 09/01/06 to 08/31/09 $48,735/year direct costs. No-cost time extension 09/01/09 to 12/31/09 Renewed funding at $35K/year, 1/1/10 – 12/30/11 Blue Cross Blue Shield of Michigan Foundation (D. Gordon, PI 2006-2010, and co-PI 2010-present, 5% effort): “Encouraging Physicians to Practice in Underserved Communities: Medical School Rotation Strategy” NIH PO1 HL57346 “Molecular Genetics Coagulation Disorders” 4/1/09 – 3/31/14 PI: D. Ginsburg Morphology Core Director: D. Gordon (5%); Direct costs ($74,878/year) UL1 RR024986 (K. Pienta, PI) 09/17/2007 – 05/31/2012 KL2 RR024987 (Mentored Career Development Component) TL1 RR024988 (Predoctoral Training Grant Component) NIH / NCRR $54,619,564 total direct cost Michigan Institute for Clinical and Health Research (MICHR); CTSA grant D. Gordon: co-Director, Community Engagement Component (5% effort) HRSA 1D18HP13634 0100: 9/1/2009 to 8/31/2012 Department of-Health Resources and Services Administration (HRSA) HCOP grant: “An Interdisciplinary Approach to Enhancing Access to Health Care” PI: M. Woolfolk; Co-I: D. Gordon. This is a summer academic enrichment program run by the Univ. of Michigan Schools of Dentistry and Medicine and which mentors underrepresented minority and socioeconomically disadvantaged undergraduate students towards dental and medical school. $384,637.00 total annual direct cost. Project Director, National Institute of Health (HL-03174), “The Biochemistry of Vascular Smooth Muscle Cell Differentiation and Proliferation,” Earl P. Benditt, P.I. 3/1/85 2/29/88, ($58,870/yr). 5 6 Robert Wood Johnson Foundation Fellowship (10870), “Smooth Muscle Cell Differentiation” 1/1/85 - 12/31/88 ($58,678/yr). Project Director, Grant-in-Aid from The National American Heart Association and its Washington State Affiliate (88-0916), “Cell Proliferation in the Human Artery Wall”, 7/1/88 - 6/30/91 ($28,000/yr). Principal Investigator, National Institute of Health, (HL-42119-01), “Proliferation and Growth Factors in Atherosclerosis”, 12/1/88 - 11/30/93 ($120,264/yr) National Institute of Health, (RO1 HL-43322-01), “Cells and Molecules Mediating Graft Atherosclerosis” S. Coughlin, P.I.; D. Gordon, P.I. for Seattle subcontract 7/1/89 4/30/94, ($50,134/yr). (P50 HL-42770 SCOR), “Vascular Disease” D.E. Strandness, P.I.; Morphology Core B: D. Gordon, Director, 1/1/90 - 12/1/91, ($146,294/yr). Michigan American Heart Assoc. Grant-in-Aid: “The Patterns of Collagen Synthesis During Arterial Restenosis” D. Gordon, P.I., 7/1/93 - 6/30/94, ($27,000). Michigan Diabetes Research and Training Center Pilot/Feasibility Grant: “Cell proliferation and collagen gene expression in human diabetic atherosclerosis ” D. Gordon, P.I., 12/1/94 - 11/30/95, ($24,000/yr). National American Heart Assoc. Grant-in-Aid: “Vascular Biology Patterns of Collagen Gene Expression in Human Atherosclerosis” D. Gordon, P.I., 7/1/93 - 6/30/96, ($40,000/yr). American Heart Assoc. of Michigan: “A Gene Therapy Approach to Transplant Arteriosclerosis” D. Gordon, P.I., 7/1/95 - 6/30/97, ($28,000/yr). Taisho Excellence in Research Program Grant: “The Fibrogenic Intimal Cell of Atherosclerosis” D. Gordon, P.I., 12/1/95 - 11/30/98, ($70,000/yr). National Institutes of Health, NIH DK42706: “Expression of recombinant TGF-beta in arteries” E.G. Nabel, P.I.; D. Gordon, Co-Investigator, 8/1/93 - 7/31/98 ($161,341/yr). National Institutes of Health, NIH-NIAID AI36606: “Molecular Genetic Interventions for Pediatric AIDS” G.J. Nabel, P.I.; D. Gordon, Co-director of Morphology Core, 8/1/94 7/31/98, ($115,911/yr). NIH-NHLBI HL53466: “Gene Transfer into the Pulmonary Vasculature” E.G. Nabel, P.I.; D. Gordon, Co-Investigator, 12/1/94 - 11/30/98, ($170,314/yr direct costs). Civilian Research & Development Foundation, CRDF Award #RN1-416: “The role of angiogenesis in human atherosclerosis.” D. Gordon, U.S. P.I.; A. Orekhov, Russian P.I. (collaborative grant) 10/1/97 - 9/30/99, ($35,000/2 years direct costs). (NOTE: This grant was given up when I became employed at Parke-Davis Pharmaceutical Research, which is a “for profit” institution.) Association of American Medical Colleges, Health Professions Partnership Initiative: “Health Occupations Partners in Education” (HOPE) D. Gordon, P.I. 7/1/98 - 6/30/03, ($70,000/yr direct costs). 6 7 (NOTE: This is a grant out of the Univ. of Michigan Medical School's Dean's office. I relinquished the position of principal investigator as a result of employment at ParkeDavis Pharmaceutical Research, although Parke-Davis is a formal partner in this grant funded effort.) National Institutes of Health, (HL-42119-01): “Cell growth and collagen synthesis in atherosclerosis” D. Gordon, P.I., 4/1/95 - 3/31/98 with no-cost extension until March, 1999, ($148,810/yr). Kellogg Foundation: “Kellogg Michigan Consortium for Minority Health and Development” D. Gordon PI; 2/1/03 – 1/31/04 ($100,000) M01-RR00042 (R. Kelch) Gen. Clin. Research Center3/01/2006 – 9/17/2007 NIH National Center for Research Resources $5.8 Million D. Gordon: Director of the Minority Health Research Program (5%) NIH PO1 HL57346 “Molecular Genetics Coagulation Disorders” 7/1/03 – 6-30-08 PI: D. Ginsburg Morphology Core Director: D. Gordon (10%); Direct costs ($99,717/year) Howard Hughes Medical Institute: Health Occupations Partners in Education (HOPE) (HHMI Precollege Science Education Initiative): D. Gordon PI; 9/1/03 – 8/31/08 ($538,574) With a no-cost time extension until August 30, 2009. Community Foundation of Greater Flint: “Telemedicine Outreach for Underserved Populations” D. Gordon: PI, March 2013 – Feb. 2014 CERTIFICATION AND LICENSURE Board 1985 Anatomic Pathology License 1980 1992 Washington Michigan MILITARY SERVICE None HONORS AND AWARDS 1973 1979 2004 2004 2009 Phi Beta Kappa; summa cum laude Sigma Xi (Amherst College) cum laude (Harvard Medical School) Univ. of Michigan Harold R. Johnson Diversity Service Award 2003-2004 Medical Student Award for Teaching Excellence (for pathology laboratory instructors) National Center for Institutional Diversity Exemplary Diversity Engagement and Scholarship Award 7 8 MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES Society for Cardiovascular Pathology Councilor 1992-1995, Member 2000-2010 National Medical Association 2003-2011 Association of American Medical Colleges 2001- 2011 Univ. of Michigan representative for the Minority Affairs Section (Group on Student Affairs—GSAMAS) 2001-2009 Univ. of Michigan representative for the Group on Diversity and Inclusion, 2009- 2011 American Society for Investigative Pathology Membership and Program Committees 1992-1996 Membership 1997-2011 Minisymposium Chair, 1996 Exp. Biol. Meeting International Society for Heart Transplantation U.S. and Canadian Academy of Pathology, Inc. Arteriosclerosis Council, American Heart Association Abstract reviewer for National Meeting, 1995 North American Vascular Biology Organization 1995 - 2010 American Heart Association, Michigan Affiliate Program Committee, 1994-2000 JOURNAL EDITORIAL BOARDS Cardiovascular Pathology TEACHING ACTIVITIES University of Washington 1985-1991 1985-1989 1985-1990 1987-1991 1990-1991 1985-1991 1989-1991 1985-1991 Lecturer in HuBio 520 course (“Tissue Reaction to Injury”) Laboratory Section leader for Introduction to Pathology Course for first year medical students (HuBio 520; 6-8 contact hours per year) Lecturer for Pathology Residents Seminar series (one contact hour) on infarct dating Lecturer in Introduction to Pathology Course for first year medical students (HuBio 520; 3 contact hours yearly since 1987) on atherosclerosis and myocardial infarction Lecturer in Introduction to Pathology Course for non-medical students (Pathology 410; two contact hours per year) on atherosclerosis and myocardial infarction Director of weekly Autopsy Conference and Medicine/Pathology Correlation Conference (one hour weekly) Presenter of pathology at monthly thoracic surgery Morbidity and Mortality Conference Give monthly talks about Pathology to visiting high school and college students (particularly minority groups) (1/2 contact hour) University of Michigan 1993-present 1994-1997 1993-1995 1995-present 2001- present Lecturer Cardiovascular Sequence for 2nd year medical students. Chair of Vascular Biology Journal Club Laboratory Instructor Pathology 600 Systemic Pathology Laboratory Instructor Pathology (for 2nd year organ systems courses for medical students) Lecturer Pathology Course for Dental Students (cardiovascular pathology lectures). 8 9 2005- 2011 Lecturer in Dept. of Pathology general pathology course for graduate students (Path 581). Graduate student and Postdoctoral fellows (training/mentoring) 1990-1991 F. Frank Isik, M.D. Frank is currently Asst. Prof. Plastic Surgery, Univ. of Washington, Seattle. 1991-1995 Mark D. Rekhter, M.D., Ph.D. Mark is currently a Senior Scientist at Pfizer, Ann Arbor. 1996-1997 Sergey Filippov, M.D. Sergey is currently a Research Associate, Dept. of Internal Medicine, Univ. of Michigan (Stephen Weiss Laboratory) 1997-1999 Yunling Song, M.D. Yunling is currently a scientist at Pfizer, Ann Arbor Indirect Postdoctoral Fellows (officially in other labs, but mentored by me) 1993-1995 Vincent J. Pompili, M.D. Vince was in the laboratory of Elizabeth Nabel in Cardiology. He is now an Assistant Prof. At the Cleveland Clinic in Cardiology. 1995-1997 Raj Sarkar, M.D., Ph.D. Raj was working with R. Clinton Webb in Physiology, and is currently an Asst. Prof. At Univ. of California San Francisco (Vascular Surgery). 1994-1996 Robert Simari, M.D. Rob was working in the laboratory of Elizabeth Nabel in Cardiology. He is now an Asst. Prof. at Mayo Clinic in Cardiology. 1997-2009 He Wang, M.D., Ph.D. He was a postdoctoral fellow with Joan Keiser at Pfizer, but was assigned to my laboratory, and did research under my direction. As of July 1, 2006 a resident in our Univ. of Michigan Dept. of Pathology. 1998-2000 AtaçTürkay, M.D. I was on his Ph.D. thesis committee (Human Genetics). He took a faculty position at a different institution (Chicago). 2004-2006 Brenda Sun Yong Cho (thesis committee). Research mentor is Gilbert Upchurch (Dept. of Surgery) and research focus is aneurysm biology. EXTRAMURAL INVITED RESEARCH PRESENTATIONS “Growth factors and cell proliferation in human atherosclerosis.” Alexis Carrel Conference on Transplant Arteriosclerosis, 1989. “Cell proliferation in human coronary and carotid arteries.” Altschul Conference on Arteriosclerosis, Saskatoon, Canada, 1989. “Cell proliferation in human coronary arteries.” The Lofland Conference on Arteriosclerosis, San Antonio, Texas, 1990. “Growth factors and cell proliferation in human atherosclerosis. ” Lilly Corp., Indianapolis, IN, 1990. “Cell proliferation in human transplant coronary arteries.” The International Academy of Pathology, Chicago, IL, 1991. “Cell proliferation in human atherosclerosis.” The Department of Pathology, University of Michigan, Ann Arbor, MI, 1991. “Cell proliferation in the coronary arteries of transplanted hearts.” The Blood Vessel Club,” FASEB Meeting, Atlanta, GA, 1991. “Cell proliferation in transplant arteriosclerosis.” St. Louis University, October 25, 1991. “Cell proliferation in human arteries.” The U.S. and Canadian Academy of Pathology, Atlanta, GA, 1992. “Cell proliferation in human arterio-venous dialysis shunts.” The “Blood Vessel Club,” FASEB Meeting, Anaheim, CA , 1992. 9 10 “Cell proliferation in human atherosclerosis.” Tufts University, Division of Cardiology, Boston, MA, 1992. “Cell proliferation in human atherosclerosis.” Krannert Institute of Cardiology, Indianapolis, IN, 1992. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk at Univ. of Virginia (Department of Physiology), June 30, 1992. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Pediatric Cardiology Division, Univ. of Michigan, Feb. 2, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Cleveland Clinic Department of Vascular Biology, Feb. 18, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Department of Pathology, Univ. of Michigan, Feb. 23, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Society for Biomaterials conference held in Boston, MA, April 5, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Vascular Medicine Seminar Series, Univ. of Michigan, May 3, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given to Department of Pathology, Univ. of Toronto, Canada; May 4, 1994. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” American College of Veterinary Pathologists meeting in Toronto, Nov. 3, 1994. “Growth factors as inducers of neointimal hyperplasia.” Special symposium on “Transplant Vascular Sclerosis” sponsored by Ohio State University College of Medicine, held in Bermuda, Feb. 2, 1995. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Univ. of Michigan to Cardiology (Grand Rounds), June 6, 1995. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given at Univ. of Michigan to Gene Therapy Group (seminar series), June 8, 1995. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given to Gladstone Institute of Cardiovascular Disease (San Francisco), July 24, 1995. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given to Texas Biotech. Inst. (Houston, TX) Oct. 13, 1995. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given to Vascular Medicine Program, Univ. of Michigan, Feb. 6, 1996. “Cell Proliferation and Collagen Gene Expression in Human Atherosclerosis.” Talk given to Department of Surgery, at Univ. of Arizona (Tucson), Mar. 8, 1996. “The growth of human atherosclerosis: Cell proliferation and collagen synthesis.” U.S. and Canadian Association of Pathologists meeting (Society for Cardiovascular Pathology) Mar. 24, 1996; Washington D.C. 10 11 “Cell proliferation and collagen synthesis in human atherosclerosis.” Talk given to Genentech Inc. (San Francisco, CA) Sept. 4, 1996. “Restenosis: A Pathologist’s view.” Restenosis Summit, Cleveland, Ohio 1997. “Cell proliferation and collagen synthesis in human atherosclerosis.” Talk given to Cardiology Division, Univ. of Michigan, April 3, 1998. “Growth of human atherosclerosis.” Talk given at the 9th Annual R.W. Gunton Symposium on Cardiovascular Therapeutics, sponsored by the John P. Robarts Research Institute and presented at the University of Western Ontario, Canada (September. 11, 1998). “The cellular growth of human atherosclerosis.” Talk given to the Midwestern Vascular Surgical Society meeting in Chicago, Sept. 25, 1999. “Growth factors, cell proliferation and collagen synthesis in human atherosclerosis.” Talk given to the U.S.-Italy Joint Symposium on Genetic and Pharmacological Approaches in Vascular Biology, at the University of Milan, Italy (Dec. 2-4, 1999, sponsored by the National Institutes of Health, and the Institute of Pharmacological Sciences at the University of Milan). “Atherosclerosis in African Americans: Path Prevention and Treatment.” Ernest E. Just Symposium at Medical University of South Carolina, Feb. 14, 2003 OTHER INVITED DEAN’S OFFICE PRESENTATIONS “Diversity in Medical Education” Presentation to the Medical Educators Scholars Program, Univ. of Michigan, June 17, 2003 “Diversity in Medical Education” Presentation to the Medical Educators Scholars Program, Univ. of Michigan, May 11, 2004 “Visible and Invisible Aspects of Diversity” Presentation to Dept. of Pathology faculty and staff, May 11, 2005. “Life after the Supreme Court: How the University of Michigan maintained their minority medical school enrollment.” Keynote talk at the national American Medical Association meeting (Minority Affairs Caucus), Chicago June 17, 2005. “HPPI Sustaining Funding: The Story of our Univ. of Michigan HOPE Program.” Talk given at the Assoc. of American Medical Colleges’ Health Professionals Partnership Initiative last meeting, Wash. DC, Oct. 2, 2005. “Role of Development in Funding Outreach Clinics and Other Special Projects: Thoughts on Obtaining External Funding.” Talk given at the Assoc. of American Medical Collages GSA-MAS national meeting in Philadelphia, April 4, 2006. "Rock the Match: strengthening your ERAS application” Talk to medical students at the annual Student National Medical Association, New York, March 21, 2008. "Addressing Diversity in Graduate Medical Education: Challenges and Perspectives" Panel discussion at the annual Association of American Medical Colleges meeting, San Antonio, Texas; Nov. 4, 2008 11 12 "Rock the Match: strengthening your ERAS application” Talk to medical students at Wayne State University, Detroit, Michigan, November 10, 2008. "Rock the Match: strengthening your ERAS application” Talk to medical students at the regional Student National Medical Association, Cleveland, Ohio, November 14, 2008. "Rock the Match: strengthening your ERAS application” Talk to medical students at the national Student National Medical Association, New Orleans, Louisiana, April 10, 2009. “Rock the Match: How to beef up your application for Residency Programs.” Talk to medical students at the national Latino Medical Student Association meeting in Chicago, Illinois, Mar 6, 2010 “Community Benefits: What does it mean?” Talk to the Minority Health Research Program’s Community Advisory Board meeting in Ann Arbor, MI, Mar. 9, 2010. “Rock the Match: How to beef up your application for Residency Programs.” Talk to medical students at the Student National Medical Association meeting in Chicago, Illinois, April 2, 2010 “Diversity: Threading the Needle Between Federal Affirmative Action Mandates and State Constitutional Amendments in Four States: Univ. of Michigan Medical School Experience. (panel discussion) Assoc. of American Medical Colleges meeting, New Orleans, Louisiana, March 24, 2011.” “Rock the Match: How to beef up your application for Residency Programs.” Talk to medical students at the Latino Medical Student Association National Meeting at the Univ. of California, Irvine School of Medicine (April, 3, 2011) “Rock the Match: How to beef up your application for Residency Programs.” Talk to medical students at the Student National Medical Association Meeting in Indianapolis, (April, 22, 2011) Panelist for Kaplan Inc.’s, “Kaplan Live, Online Medical School Insider Event” (national/international webcast featuring various premedical advisors and admissions related personnel). New York City, May 23, 2011. Panelist for the Univ. of Michigan Staff Mentoring and Coaching for Diversity Conference (Ann Arbor, MI), June 27, 2011. “Medical School Curriculum.” Workshop for American Medical Student Association’s pre-medical conference in Sacremento, CA (Oct 8-9, 2011) “Rock the Match: How to beef up your application for Residency Programs.” Talk to medical students at the central regional Student National Medical Association Meeting in Ann Arbor, (October, 22, 2011) “Work hard to creatively address unmet needs and you will succeed.” Keynote talk for DNA Night (program to engage Flint area high school students in medical genetics.) University of Michigan-Flint December 20, 2011 “Manage your stress.” Keynote talk for Genesee Early College graduating class, University of MichiganFlint; May 19, 2013 12 13 COMMITTEE AND ADMINISTRATIVE SERVICE University of Washington 1985-1991 1985-1991 1985-1991 Lecturer to Pathology Residents on Cardiovascular Pathology Director, Autopsy Service, University Hospital, Seattle, WA Director, Cardiovascular Pathology, University Hospital, Seattle, WA University of Michigan 1992-present 1992-1998 1994-1997 1994-1997 1996-1997 2002-2011 2001-2011 2003-2011 2002-2011 2004-2008 2006-2008 Attending - autopsy service of Univ. Hospital Univ. of Michigan Diversity Advisory Group Assistant Dean for Faculty Affairs, University of Michigan, Ann Arbor, MI Faculty Affairs Advisory Group Medical School Dean Search Committee Director of the Office of Diversity and Career Development, U. of M. Medical School Medical School Executive Admissions Committee University of Michigan Diversity Council (member) Director, Minority Health Research Program, Univ. of Michigan School of Medicine. Member, Planning Group for the Univ. of Michigan National Center for Institutional Diversity. Member, Univ. of Michigan Advisory Committee for the National Center for Institutional Diversity-ADVANCE Project “Advancing Diversity and Excellence in Science and Engineering.” National 2001-2005 2001-2009 2009-2011 2008-2010 2009-2011 National Academy of Sciences Committee for “Assessment for NIH Minority Research Training Programs Phase 3” Member of the Association of American Medical Colleges Group on Student Affairs – Minority Affairs Section (Univ. of Michigan representative). Member of the Association of American Medical Colleges Group on Diversity and Inclusion (Univ. of Michigan representative). Association of American Medical Colleges Council of Deans Fellow Member, Robert Wood Johnson Foundation Alumni Roundtable on Health and Health Care 13 14 BIBLIOGRAPHY Completed Publications in Scientific Journals: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. Gordon D and Hove, MJ: Triplet excitons in the ionic radical salts of 2,3 dichloro-5, 6-dicyanobenzoquinone. J. Chem. Phys;59:3419-3420, 1973. Gordon D, Guyton, JR and Karnovsky, MJ: Intimal alterations in rat aorta induced by stressful stimuli. Lab. Invest;45:14-27, 1981. Comess, KA, Zibelli, LR, Gordon D and Frederickson, SR: Acute, severe, aortic regurgitation in Behcet's syndrome. Ann. Int. Med;99:639-640, 1983. Foy, HM, Maier, RV, Gordon D and Lee, MJ: Granulomatous peritonitis secondary to pinworm infection. Infect. in Surg, pp.15-28; 1984. Gown, AM, Vogel, AM, Gordon D and LU, PL: A smooth muscle-specific monoclonal antibody recognizes smooth muscle actin isozymes. J. Cell Biol;100:807-813, 1985. Owens, GK, Loeb, A, Gordon D and Thompson, MM: Expression of smooth muscle-specific alpha-isoactin in cultured vascular smooth muscle cells: relationship between growth and cytodifferentiation. J. Cell Biol;102:343-352, 1986. Gordon D, Mohai, LG and Schwartz, SM: Induction of polyploidy in cultures of neonatal rat aortic smooth muscle cells. Circ. Res; 59:633-644, 1987. Tsukada, T, Tippens, D, Gordon D, Ross, R and Gown AM: HHF35, a muscle-actin-specific monoclonal antibody. I. Immunocytochemical and biochemical characterization. Am. J. Pathol; 126:51-60, 1987. Gordon D, Schwartz SM: Replication of arterial smooth muscle cells in hypertension and atherosclerosis. Am. J. Cardiol; 59(2): 44A-48A, 1987. Reilly, DF, Gordon D, Schwartz, SM: Determination and comparison of the aortic polyploid smooth muscle content of human hypertensive subjects and normotensive controls. Acta Physiologica Scandinavica; 133(Suppl. 571):181-188, 1988. Wilcox, JN, Smith, K, Williams, LT, Schwartz, SM and Gordon D: Platelet-derived growth factor mRNA detection in human atherosclerotic plaques, by in situ hybridization. J. Clin. Invest; 82:1134-1143, 1988. Wilcox, JN, Smith, K, Schwartz, SM, Gordon D: Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc. Natl. Acad. Sci. USA;86:2839-2843; l989. Gordon D, Schwartz, SM, Benditt, EP and Wilcox, JN: Growth factors and cell proliferation in human atherosclerosis. Transplantation Proceedings; 21(4):3692-3694, 1989. Swedberg, SH, Brown, BG, Sigley, R, Wight, TN, Gordon D and Nicholls, SC: Intimal fibromuscular hyperplasia at the venous anastomosis of PTFE grafts in hemodialysis patients: Clinical, immunocytochemical, light and electron microscopic assessment. Circulation; 80:1726-1736, 1989. Allen, MD, Tsuboi, H, Togo, T, Eary, JF, Gordon D, Thomas, R and Reichenbach, DD: Detection of cardiac allograft rejection and myocyte necrosis, by monoclonal antibody to cardiac myosin. Transplantation; 48(6):923-928, 1989. Alpers, CE, Gordon D and Gown, AM: Immunophenotype of vascular rejection in renal transplants. Modern Pathology; 3(2):198-203, 1989. Gordon D, Reidy, MA, Benditt, EP and Schwartz, SM: Cell proliferation in human coronary arteries. Proc. Natl. Acad. Sci; 87:4600-4604, 1990. Kohler, T, Kirkman, TR, Gordon D and Clowes, AW: Mechanism of Long-Term Degeneration of Arterialized Vein Grafts. Am. J. of Surg;160:257-261, 1990. Goldman, ML, Whitley, MA, Gordon D, Shaw, DWW, Nicholls, SC, Wan, C and Nelson, JA: Yucatan Microswine Model of Arteriosclerosis: Angiographic-Histologic Correlation. Seminars In Interventional Radiology;7(2):80-85, 1990. Gordon D and Schwartz, SM: Cell proliferation in human atherosclerosis.Trends in Cardiovascular Medicine;1:24-28, 1991. McKeown, PP, Tsuboi, H, Togo, T, Thomas, R, Tuck, R and Gordon D : Growth of tracheal anastomoses using PDS or poly propylene sutures and continuous versus interrupted suturing techniques. Ann. Thor. Surg; S1(4):636-641, 1991. Allen, MD, Shoji, Y, Fujimura, Y, Eary JF, Gordon D, Thomas, R and Reichenbach, D: Effect of cyclosporine on the uptake of monoclonal antibody to cardiac myosin. J. Heart Transplantation; 10:775-781, 1991. 14 15 23. Carlos, T, Gordon D, Fishbein, D, Himes, V, Coday, A, Ross, R and Allen, MD: Vascular cell adhesion molecule-1 is induced on endothelium during acute rejection in human cardiac allografts. J. Heart and Lung Transpl; 11:1103-1109, 1992. 24. McKeown, PP, Tsuboi, H, Togo, T, Thomas, R, Tuck, R and Gordon D: Growth of tracheal anastomoses using PDS or poly propylene sutures and continuous versus interrupted suturing techniques. Ann. Thor. Surg; 51:636-641, 1991. 25. Nelken, N, Coughlin, S, Gordon D and Wilcox, JN: Monocyte chemoattractant protein-1 in human atheromatous plaques. J. Clin. Invest., 1991;88:1121-1127. 26. Isik, FF, Ferguson, M, Yamanaka, E and Gordon D: Proliferating cell nuclear antigen: A marker for cell proliferation in autopsy tissues. Arch. Pathol. Lab. Med; 116:1142-1146, 1992. 27. Gordon D: Growth factors and cell proliferation in human transplant arteriosclerosis. J. Heart Lung Transplant; 11(3 Pt 2): S7, 1992. 28. Isik FF, Valentine HA, McDonald TO, Baird A, Gordon D: Localization of bFGF in human transplant coronary atherosclerosis. Ann. N. Y. Acad. of Sciences; 638:487-488, 1992. 29. Turka LA, Linsley PS, Lin H, Brady W, Leiden JM, Wei R, Gibson ML, Zheng X, Myrdal S, Gordon D, Bailey T, Bolling SF, Thompson CB. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc. Natl. Acad. Sci. USA; 89:11102-11105, 1992. 30. O'Brien KD, Gordon D. Deeb S, Ferguson M, Chait A: Lipoprotein lipase is synthesized by macrophagederived foam cells in human coronary atherosclerotic plaques. J. Clin. Invest; 89:1544-1550, 1992. 31. Isik FF, McDonald TO, Ferguson M, Yamanaka E, Gordon D: Transplant arteriosclerosis in a rat aortic model. Am. J. Pathol; 141:1139-1149, 1992. 32. Urieli-Shoval S; Meek RL; Hanson RH; Ferguson M; Gordon D; Benditt EP: Preservation of RNA for in situ hybridization: Carnoy's versus formaldehyde fixation. J-Histochem-Cytochem; Dec; 40(12): 1879-85, 1992. 33. Huth M Gordon D Verrier ED Otto CM: Aortic valvular fibroma as a source of systemic emboli in POEMS syndrome. J. Am. Soc. Echocardiogr;4(4):401-4, 1992. 34. Allen MD Shoji Y Fujimura Y Gordon D Thomas R Brockbank KG Disteche CM: Growth and cell viability of aortic versus pulmonic homografts in the systemic circulation. Circulatio; 84(5 Suppl):III94-9, 1992. 35. Allen MD McDonald TO Carlos T Himes V Fishbein D Aziz S Gordon D Endothelial adhesion molecules in heart transplantation. J Heart Lung Transplant; 11:S8-13, 1992. 36. Nabel EG, Gordon D, Yang Z, San H, Plautz GE, Gao X, Huang L, Nabel GJ: Gene transfer in vivo with DNALiposome Complexes: Lack of Autoimmunity and Gonadal Expression. Human Gene Therapy; 3:649-656, 1992. 37. Finta KM, Fischer MJ, Lee L, Gordon D, Pitt B, Webb RC: Ramipril prevents impaired endotheliumdependent relaxation in arteries from rabbits fed an atherogenic diet. Atherosclerosis; 100:149-156, 1993. 38. Nabel EG, Yanz Z, Liptay S, San H, Gordon D, Haudenschild CC, Nabel GJ: Recombinant platelet-derived growth factor B gene expression in porcine arteries induces intimal hyperplasia in vivo. J. Clin. Invest; 91:18221829, 1993. 39. Nabel EG, Shum L, Pompili VJ, Yang ZY, San H, Shu HB, Liptay S, Gold L, Gordon D, Derynck R, Nabel GJ: Direct gene transfer of transforming growth factor 1 into arteries stimulates fibrocellular hyperplasia. Accepted to Proc. Natl. Acad. Sci. USA; 90:10759-10763, 1993. 40. Rekhter MD, Zhang K, Narayanan AS, Phan S, Schork MA, Gordon D: Type I collagen gene expression in human atherosclerosis: Localization to specific plaque regions. Am. J. Pathol ;143:1634-1648, 1993. 41. O'Brien,E.R.; Alpers,C.E.; Stewart,D.K.; Ferguson,M.; Tran,N.; Gordon,D.; Benditt,E.P.; Hinohara,T.; Simpson,J.B.; Schwartz,S.M. Proliferation in primary and restenotic coronary atherectomy tissue: Implications for antiproliferative therapy Circ. Res; 73:223-231, 1993. 42. Nabel GJ, Nabel EG, Yang Z, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE: Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. USA; 90:11307-11311, 1993. 43. San H, Yang Z, Pompili VJ, Jaffe ML, Plautz GE, Xu L, Felgner JH, Wheeler CJ, Felgner PL, Gao X, Huang L, Gordon D, Nabel GJ, Nabel EG: Safety and short-term toxicity of a novel cationic lipid formulation for human gene therapy. Human Gene Therapy; 4:781-788, 1993. 44. Beach KW, Hatsukami T, Detmer PR, Primozich JF, Ferguson MS, Gordon D, Alpers CE, Burns DH, Thackray BD, Strandness DE. Carotid artery intraplaque hemorrhage and stenotic velocity. Stroke; 24:314319, 1993. 15 16 45. Aziz S, Tada Y, Gordon D, McDonald TO, Fareed J, Verrier ED: A reduction in accelerated graft coronary disease and an improvement in cardiac allograft survival using low molecular weight heparin in combination with cyclosporine. J.Heart Lung Transplant; 12(4):634-43, 1993. 46. Rekhter MD, Gordon D: Does platelet-derived growth factor-A chain stimulate proliferation of aterial mesenchymal cells in human atherosclerotic plaques? Circ. Res; 75:410-417, 1994. 47. Rekhter, MD, Gordon D: Cell proliferation and collagen synthesis are two independent events in human atherosclerotic plaques. J. Vasc. Res; 31:280-286, 1994. 48. O'Brien KD, Ferguson M, Gordon D, Deeb SS, Chait A: Lipoprotein lipase is produced by cardiac myocytes rather than interstitial cells in human myocardium. Arterioscler. Thromb. 14:1445-1451, 1994. 49. Lin H, Bolling SF, Linsley PS, Wei RQ, Gordon D, Thompson CB, Turka LA: Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med; 178(5):1801-6, 1994. 50. Gibran NS, Isik FF, Heimbach DM, Gordon D: Basic fibroblast growth factor in the early human burn wound. J. Surg. Res; 56:226-234, 1994. 51. Muller DWM, Gordon D, San H, Yang ZY, Pompili VJ, Nabel GJ, Nabel EG: Catheter-mediated pulmonary vascular gene transfer and expression. Circ. Res; 75:1039-1049, 1994. 52. Muller DWM, Golomb G, Gordon D, Levy RJ: “Site-specific dexamethasone delivery for the prevention of neointimal thickening after vascular stent implantation.” Coronary Artery Disease; 5:435-442, 1994. 53. Ohno T, Gordon D, San H, Pompili VJ, Imperiale MJ, Nabel GJ, Nabel EG: Inhibition of vascular smooth muscle cell proliferation following arterial injury by genetic intervention. Science; 265:781-784, 1994. 54. Isik FF, Clowes AW, Gordon D: Elastin expression in a model of acute arterial graft rejection. Transplantation; 58:1246-1251, 1994. 55. Wilcox JN, Nelken NA, Coughlin SR, Gordon D, Schall TJ: Local expression of inflammatory cytokines in human atherosclerotic plaques. J. Atheroscler. Thromb; 1: S10-3, 1994. 56. Hatsukami TS, Thackray BD, Primozich JF, Ferguson MS, Burns DH, Beach KW, Detmer PR, Alpers C, Gordon D, Strandness DE Jr: Echolucent regions in carotid plaque: preliminary analysis comparing threedimensional histologic reconstructions to sonographic findings. Ultrasound Med. Biol; 20(8):743-9, 1994. 57. Lin H, Wei RQ, Gordon D, Linsley P, Turka LA, Bolling SF: Review of CTLA4Ig use for allograft immunosuppression. Transplant. Proc; 26(6):3200-1, 1994. 58. Plautz GE, Nabel EG, Fox B, Yang ZY, Jaffe M, Gordon D, Chang A, Nabel GJ: Direct gene transfer for the understanding and treatment of human disease. Ann. N.Y. Acad. Sci; 716:144-53, 1994. 59. Rekhter MD, Gordon D: Active proliferation of different cell types, including lymphocytes in human atherosclerotic plaques. Am. J. Pathol; 147:668-677, 1995. 60. Kolpakov V, Gordon D, Kulik TJ: Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circ. Res; 76:305-309, 1995. 61. Pompili VJ, Gordon D, San H, Yang Z, Muller DWM, Nabel GJ, Nabel EG: Expression and function of a recombinant PDGF B gene in porcine arteries. Arterioscler. Thromb. Vasc. Biol; 15:2254-2264, 1995. 62. Kolpakov V, Rekhter MD, Gordon D, Wang WH, Kulik TJ: Effect of mechanical force on growth and matrix protein synthesis in the in vitro pulmonary artery: Analysis of the role of individual cell types. Circ Res; 77:823-831, 1995. 63. Thackray BD, Burns DH, Fergurson MS, Gordon D, Beach KW, Hatsukami T, Detmer PR, Primozich JF, Strandness DE. A new method of studying plaque morphology. Amer. J. of Cardiac Imaging; 9:149-156, 1995. 64. Kang S, Kim KJ, Griffiths CEM, Wong TY, Talwar HS, Fisher GJ, Gordon D, Hamilton TA, Ellis CN, Voorhees JJ. Topical tretinoin (retinoic acid) improves early stretch marks. Arch Dermatol; 132:519-526, 1996. 65. Schwartz SM, Gordon D, Mosca RS, Bove EL, Heidelberger KP, Kulik TJ. Collagen content in normal, pressure and pressure-volume overloaded developing human hearts. Am J Cardiol; 77:734-738, 1996. 66. Simari RD, San H, Rekhter M, Ohno T, Gordon D, Nabel GJ, Nabel EG. Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. J Clin Invest; 98:225-235, 1996. 67. Yang ZY, Simari RD, Perkins ND, San H, Gordon D, Nabel GJ, Nabel EG. Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury. Proc Natl Acad Sci USA; 93:7905-7910, 1996. 68. Sarkar R, Meinberg EG, Stanley JC, Gordon D, Webb RC. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells. Circ Res; 78:225-230, 1996. 16 17 69. Rekhter M, Nicholls S, Ferguson M, Gordon D. Cell proliferation in human arteriovenous fistulas used for hemodialysis. Arteriosclerosis and Thrombosis; 13:609-617, 1996. 70. Nabel GJ, Yang ZY, Nabel EG, Bishop K, Marquet M, Felgner PL, Gordon D, Chang AE. Direct gene transfer for treatment of human cancer. Ann. N.Y. Acad. Sci; 772:227-31, 1996 71. Chang MW, Ohno T, Gordon D, Lu MM, Nabel GJ, Nabel EG, Leiden JM. Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery. Mol. Med; 1(2):172-81, 1996. 72. Fox BA, Woffendin C, Yang ZY, San H, Ranga U, Gordon D, Osterholzer J, Nabel GJ: Genetic modification of human peripheral blood lymphocytes with a transdominant negative form of Rev: safety and toxicity. Hum. Gene Ther; 6(8):997-1004, 1995. 73. Rekhter MD, O'Brien E, Shah N, Schwartz SM, Si mpson JB, Gordon D: The importance of thrombus organization and stellate cell phenotype in collagen I gene expression in human, coronary atherosclerotic and restenotic lesions. Cardiovascular Research; 32:496-502, 1996. 74. Nabel GJ, Gordon D, Bishop DK, Nickoloff BJ, Yang ZY, Aruga A, Cameron MJ, Nabel EG, Chang AE. Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc Natl Acad Sci USA; 93:15388-15393, 1996. 75. DeBruyne LA, Chang AE, Cameron MJ, Yang Z, Gordon D, Nabel EG, Nabel GJ, Bishop DK. Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor V beta usage by tumor-infiltrating lymphocytes. Cancer Immunol. Immunother; 43(1): 49-58, 1996. 76. Welling TH, Davidson BL, Zelenock JA, Stanley JC, Gordon D, Roessler BJ, Messina LM. Systemic delivery of the interleukin-1 receptor antagonist protein using a new strategy of direct adenoviral-mediated gene transfer to skeletal muscle capillary endothelium in the isolated rat hindlimb. Hum. Gene Ther; 7(15):1795-802, 1996. 77. Stephan DJ, Yang ZY, San H, Simari RD, Wheeler CJ, Felgner PL, Gordon D, Nabel GJ, Nabel EG. A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo. Hum. Gene Ther; 7(15):1803-12, 1996. 78. Isik FF, Coughlin SR, Nelken NA, Clowes AW, Gordon D. JE gene expression in an animal model of acute arterial graft rejection. J. Surg. Res; 60(1):224-31, 1996. 79. Muller DW, Gordon D, Topol EJ, Levy RJ, Golomb G. Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting. Am. Heart J; 131(2):211-8, 1996. 80. Sarkar R, Gordon D, Stanley JC, Web RC. Cell cycle effects of nitric oxide on vascular smooth muscle cells. Am. J. Physiol. 272:10050-10057, 1997. 81. Sarkar R, Gordon D, Stanley JC, Webb RC. Dual cell cycle-specific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells. J. Hypertens; 15(3):275-283, 1997. 82. Arai H, Gordon D, Nabel EG, Nabel GJ. Gene transfer of Fas ligand induces tumor regression in vivo. Proc. Natl. Acad. Sci. USA; 94(25):13862-7, 1997. 83. Stephan D, San H, Gordon D, Nabel GJ, Nabel EG. [Gene transfer of interferon beta inhibits vascular smooth muscle cell proliferation in vitro and in animal model of arterial injury.] Arch. Mal. Coeur. Vaiss; 90(8):1121-5, 1997. 84. Stephan D, San H, Yang ZY, Gordon D, Goelz S, Nabel GJ, Nabel EG. Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon. Mol. Med; 3(9):593-9, 1997. 85. Lin H, Gastman BR, Wei RQ, Kunkel SL, Gordon D, Bolling SF. Phase-directed therapy and cardiac xenograft survival. J. Surg. Res; 72(1):84-8, 1997. 86. Jejurikar SS, Welling TH, Zelenock JA, Gordon D, Burkel WE, Carlson BM, Messina LM. Induction of angiogenesis by lidocaine and basic fibroblast growth factor: a model for in vivo retroviral-mediated gene therapy. J. Surg. Res; 67(2):137-46, 1997. 87. Hatsukami TS, Ferguson MS, Beach KW, Gordon D, Detmer P, Burns D, Alpers C, Strandness DE Jr. Carotid plaque morphology and clinical events. Stroke; 28(1):95-100, 1997. 88. Lupinetti-FM; Kneebone JM, Rekhter MD, Brockbank KG, Gordon D. Procollagen production in fresh and cryopreserved aortic valve grafts. J. Thorac. Cardiovasc. Surg; 113(1):102-7, 1997. 89. Tanner FC, Yang Z, Duckers E, Gordon D , Nabel GJ, Nabel EG: Expression of cyclin-dependent kinase inhibitors in vascular disease. Circ. Res. 82:396-403, 1998. 90. Rekhter MD, Simari RD, Work C, Nabel EG, Gordon D. Gene transfer into normal and atherosclerotic human blood vessels. Circ Res; 82:1243-1252, 1998. 91. Rekhter MD, Shah N, Simari RD, Work C, Kim J-S, Nabel GJ, Gordon D. Graft permeabilization facilitates gene therapy of transplant arteriosclerosis in rabbit model. Circulation; 98(13): 1335-41, 1998. 17 18 92. Rekhter MD, Hicks GW, Brammer DW, Work CW, Kim JS, Gordon D, Keiser JA, Ryan MJ: Animal model that mimics atherosclerotic plaque rupture. Circ Res, 83(7): 705-13, 1998. 93. Orekhov AN, Andreeva ER, Mikhailova IA, Gordon D: Cell proliferation in normal and atherosclerotic human aorta: proliferative splash in lipid-rich lesions. Atherosclerosis; Jul; 139(1): 41-8, 1998. 94. Andreeva ER, Pugach IM, Gordon D, Orekhov AN: Continuous subendothelial network formed by pericytelike cells in human vascular bed. Tissue and Cell; Feb; 30(1): 127-35, 1998. 95. Ryan, MJ, Emig LL, Hicks GW, Ramharack R, Brammer DW, Gordon D, Auerbach BJ, Keiser JA: Influence of lipoprotein(a) plasma concentration on neointimal growth in a monkey model of vascular injury. Atherosclerosis 139:137-145, 1999. 96. Kornowski R, Leon MB, Fuchs S, Vodovotz Y, Flynn MA, Gordon D, Pierre A, Kovesdi I, Keiser JA, Epstein SE: Electromagnetic-guidance for catheter-based trans-endocardial injection: a platform for intramyocardial angiogenesis therapy. J. Am. Coll. Cardiol. 35(4):1031-1039, 2000. 97. Flynn MA, Vodovotz Y, Kornowski R, Epstein S, Gordon D, Keiser JA: Use of fluorescent microspheres to localize in vivo gene transfer injection sites. BioTechniques, 28(3):470-476, 2000. 98. Song Y, Ford JW, Gordon D, Shanley CJ: Regulation of lysyl oxidase by interferon- in rat aortic smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 20: 982-988, 2000. 99. Sjöland H, Eitzman DT, Gordon D, Westrick R, Nabel EG, Ginsburg D: Atherosclerosis progression in LDL receptor-deficient and apolipoprotein E-deficient mice is independent of genetic alterations in plasminogen activator inhibitor-1. Arterioscler. Thromb. Vasc. Biol; 20(3):846-52, 2000. 100. Wang H, Gordon D, Olszewski B, Song YL, Kovesdi I, Keiser JA: Rat sponge implant model: A new system for evaluating angiogenic gene transfer. Int. J. Mol. Med; 6(6):645-653, 2000. 101. Wang H. Liu C. Song Y. Gordon D. Alavi MZ. Moore S: Expression of metalloproteinases and its inhibitor in later stage of rabbit neointima development. International Journal of Molecular Medicine. 7(1):105-12, 2001 102. Perrin LA, June JE, Rosebury W, Robertson A, Kovesdi I, Bruder JT, Kessler PD, Keiser, JA, Gordon D: Increased revascularization efficacy after administration of an adenovirus encoding VEGF121. Gene Therapy 11:512-521, 2004. 103. Wang H, Keiser JA, Olszewski B, Brammer D, Gordon D: Dose-dependent neovascularization-promoting effect of adenovirus vector CI-1023 in a rat hindlimb ischaemic model. Basic & Clinical Pharmacology & Toxicology. 95(2):76-80, 2004 Aug 104. Wang H. Keiser JA. Olszewski B. Rosebury W. Robertson A. Kovesdi I. Gordon D: Delayed angiogenesis in aging rats and therapeutic effect of adenoviral gene transfer of VEGF. International Journal of Molecular Medicine. 13(4):581-7, 2004 Apr. 105. Miller DL, Li P, Gordon D, Armstrong, WF: Histological characterization of micro-lesions induced by myocardial contrast echocardiography. Echocardiography 22(1):25-34, 2005. 106. Miller DL, Li P., Dou C., Gordon D., Edwards C. A. and Armstrong, W. F.: Influence of Contrast Agent Dose and Ultrasound Exposure on Cardiomyocyte Injury Induced by Myocardial Contrast Echocardiography in Rats. Radiology 2005;237:137-143 107. Shen Y, Bodary PF, Vargas FB, Homeister JW, Gordon D, Ostenso KA, Shayman JA, and Eitzman DT: Galactosidase A deficiency leads to increased tissue fibrin deposition and thrombosis in mice homozygous for the Factor V Leiden mutation.” Stroke 2006 37: 1106 – 1108 108. Miller DL, Li P, Dou C, Armstrong WF, Gordon D. Evans blue staining of cardiomyocytes induced by myocardial contrast echocardiography in rats: evidence for necrosis instead of apoptosis. Ultrasound Med Biol. 2007; 33(12):1988-96. 109. Gualano SK. Bolling SF. Gordon D. Wilson A. Bach DS.: High prevalence of false chordae tendinae in patients without left ventricular tachycardia. Pacing & Clinical Electrophysiology, 2007, Suppl. 30, 1:S156-159 110. Hoashi T, Florentine MS, Gordon D, Ohye RG: Cardiac papillary fibroelastoma presenting as chorea in childhood. Pediatr. Cardiol. 2009;30:995-7 111. Faust SM. Lu G, Marini BL, Zou W, Gordon D, Iwakura Y, Yasmina Laouar Y, and Bishop DK: Role of T Cell Transforming Growth Factor Beta Signaling and IL-17 in Allograft Acceptancee and Fibrosis Associated with Chronic Rejection" J. Immunol. 2009;183:7297-7306 112. Xu Z, Owens G, MD, Gordon D, Cain C, Ludomirsky A: Noninvasive creation of an atrial septal defect by histotrypsy in a canine model. Circulation 2010, 121:742-749 113. Bhavsar J, Gordon D, Shea M: Listeria myocarditis with an atypical intracavitary vegetation/thrombus. Heart 2010, 96:1637. [case report] 18 19 114. Sean J English, Jose A Diaz, Xia Shao, David Gordon, Melissa Bevard, Gang Su, Peter K Henke, Virginia E Rogers, Gilbert R Upchurch Jr and Morand Piert: Utility of 18F-FDG and 11C-PBR28 microPET for the assessment of rat aortic aneurysm inflammation. EJNMMI Research (accepted for publication December 2013) Chapters in Books and Invited Reviews 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. Gordon D and Schwartz, SM: “Arterial smooth muscle differentiation”, in: JH Campbell and GR Campbell (eds.). In: Vascular Smooth Muscle in Tissue Culture, 1987. Wilcox, JN, Schwartz, SM and Gordon D: “Local production of PDGF in the human atherosclerotic plaque”, in: Habenicht, Springer-Verlag and Heidelberg (eds.), In: Growth Factors, Differentiation Factors and Cytokines, 1990. Gordon D: “Cell proliferation in human arteries”. Cardiovascular Pathology, 1992. Nabel GJ, Nabel EG, Yang Z, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE: “Molecular genetic interventions for cancer.” Cold Spring Harbor Symposia on Quantitative Biology. Vol LIX:699-707, 1994. Gordon D and Rekhter MD. “Cell proliferation and collagen gene expression in human intimal hyperplasia”. In: Dorbin (ed), Intimal Hyperplasia, 1994. Gordon D and Nable EG: “Growth factors as inducers of neointimal hyperplasia”. In: Orosz, Sedmak and Ferguson (eds.), In: Transplant Vascular Sclerosis, 1995. Kohler T and Gordon D. “Cerebrovascular atherosclerosis”. In: Zierler (ed), Surgical Management of Cerebrovascular Disease, 1995. Gordon D. “Pathology of Carotid artery restenosis”. In: Ernst and Stanley (eds), Current Therapy in Vascular Surgery, 1995 edition (Elsevier). Gordon D. “Transplant Arteriosclerosis”. In: Ross and Topol (eds). Atherosclerosis and Coronary Artery Disease, 1996. Gordon D., Rekhter MD: “The growth of human atherosclerosis: Cell proliferation and collagen synthesis.” Cardiovasc. Pathol. 6:103-116, 1997. Gordon D, Song Y: “The Pathology of Human Carotid Restenosis.” In Ernst and Stanley (eds), Current Therapy in Vascular Surgery, 1999. (Elsevier) Gordon D. “Transplant Arteriosclerosis” (Ch. 43, pp. 623-635) in Atherothrombosis and coronary Artery Disease ed. Fuster, Topol, and Nabel. Copyright 2005 by Lippincott Williams & Wilkins. Gordon D. “Pathology of Carotid artery restenosis”. In: Stanley, Veith & Wakefield (eds), Current Therapy in Vascular and Endovascular Surgery, 2014 edition (Elsevier) Abstracts, Preliminary Communication, Panel Discussions (not published in full) 1. 2. 3. 4. 5. 6. 7. Gordon D, Vinter, D, Schwartz, SM and Gown, AM, Heterogeneity in the bovine aortic media. Fed. Proc. 45(3):683a,1986. Gordon D, Kollman, GD and Reichenbach, DD, Smooth muscle actin heterogeneity and developing intimal thickening in neonatal human coronary arteries. Fed. Proc., 1988. Wilcox, JN, Augustine, AJ, Smith, KM, Schwartz, SM and Gordon D, Localization of cells expressing tPA, PAII and urokinase by in situ hybridization in human atherosclerotic plaques and in the normal rhesus monkey. Abstract International Thrombosis Meeting, Aug., 1989. Gordon D, Reidy MA, Kollman G, Schwartz SM, Gown AM. Measures of cell proliferation in human coronary and carotid arteries using cyclin/PCNA immunocytochemistry. FASEB J 1989;3:1318a. Wilcox, JN, Schwartz, SM and Gordon D , Mesenchymal-appearing cells in the human saphenous vein expressing tissue factor and PDGF receptor mRNAs may contribute to coronary bypass graft failure. 63rd Scientific Sessions of the American Heart Association, Nov., 1990. Wilcox, JN, Augustine, AJ, Schall, TJ and Gordon D, Local gene expression in human coronary arteries from transplanted hearts analyzed by in situ hybridization. 63rd Scientific Sessions of the American Heart Association, Nov., 1990. Gordon D and Alpers, CE, Proliferation and growth factor expression in human transplant arteries. Presented at the 1991 U.S. and Canadian Academy of Pathology Meeting, Chicago, Illinois. 19 20 8. 9. 10. 11. 12. 13. 14. Isik FF, Coughlin SR, Clowes AW, Gordon D: JE gene expression in a animal model of transplant arteriosclerosis. FASEB J. 1993. 7:A489. Yang Z, Perkins ND, Simari RD, San H, Gordon D, Nabel GJ, Nabel EG. p21 cyclin-dependent kinase inhibitor inhibits intimal lesions through cell cycle arrest and differentiation of vascular cells. Circulation, 68th Scientific Session of the American Heart Association, Vol. 92, (2381) Oct., 1995. Simari RD, San H, Ohno T, Gordon D, Nabel GJ, Nabel EG. Regulation of cellular proliferation and intimal formation following balloon injury in hyperlipidemic rabbit arteries. Circulation, 68th Scientific Session of the American Heart Association, Vol. 92, (2393) Oct., 1995. Rekhter MD, Simari RD, Work C, Nabel EG, Gordon D. Adenovirus-mediated gene transfer into human coronary arteries and rabbit aorta. Circulation, 68th Scientific Session of the American Heart Association, Vol. 92, (2397) Oct., 1995. Shah N, Rekhter MD, Andreeva ER, Orekhov, AN. Fibrin is associated with arterial mesenchymal cell proliferation in human aortas: implications for developments and progression of atherosclerosis. FASEB J. (809) June 1996. Wang H, Keiser JA, Olszewski B, Song Y, Rosebury W, Robertson A, Kovesdi I, Gordon D. The delayed angiogenesis in aged rats can be accelerated by adenoviral gene transfer of VEGF. Circulation 100 (18): I-407, Nov. 1999. Bililolkar AN, Koelling TM, Aaronson KD, Dyke DBS, Gordon D, Matthews JC, Hummel SL, Wu AH. Potential effect of grouping grades 1B with 1A in the revised ISHLT cardiac biopsy grading system. J Heart Lung Transplant 2008;27:S243 Miscellaneous and Non Peer-Reviewed Publications: 1. Gordon, D: “Learn from Computer Industry.” In Modern Healthcare, March 16, 2010 (op-ed piece on making healthcare cheaper). Hobbies: Guitar playing, singing (including being a member of my temple’s choir), reading history/biographies, computer strategy games. I have also finished the 10 mile Crim Walk four times. [Revised, December 15, 2014] 20
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