DR. WILLIAM J. LANDIS
G. Stafford Whitby Chair and Professor of Polymer Science
Biomineralization, Tissue Engineering, Biomaterials
Research Interests:
Dr. Landis has research interests in understanding basic
mechanisms of mineralization in both vertebrates and
invertebrates; tissue engineering bone, cartilage, tendon
and other connective tissues; and the effects of
mechanical forces on the skeleton and dentition.
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Department of
Polymer Science
The University of Akron, OH
330-972-8483
[email protected]
www.uakron.edu/cpspe/facultyresearch/profile.dot?id=a43a8ed7d12a-416b-8844-f78214fea429
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Biography: William Landis has been a member of
the Department of Polymer Science at UA since
2010.
Previously he was chairman of the
Department of Biochemistry and Molecular
Pathology at the Northeast Ohio Medical
University, Rootstown, OH, and prior to that
position he was a faculty member in the
Department of Anatomy and Cellular Biology at the
Children’s Hospital and Harvard Medical School,
Boston, MA. Dr. Landis received a bachelor’s
degree in physics from the University of
Massachusetts, Amherst, and a Ph.D. in
biophysics from the Massachusetts Institute of
Technology, Cambridge, MA.
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Awards/Accomplishments:
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Distinguished Award of Council, Akron
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Harold Copp Prize, German Osteological Society
Industrial Sector Focus:
Tissue Engineering and Regenerative Medicine – Design
and development of biodegradable polymer scaffolds,
polymer electrospinning
Polymer Composites – Nanocrystal incorporation in
collagen; biological matrix-mineral formation
Unique Laboratory Facilities:
Laser capture microdissection – Isolation of single or small
clusters of cells from heterogeneous cell populations;
quantitative analysis of gene expression from one or more
cells
Recent Publications/Patents:
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Council of Engineering and Scientific Societies (2014)
Fellow of the Microscopy Society of America (2012)
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National tour speaker, Microscopy Society of America
Kappa Delta Award, America Academy of
Orthopaedic Surgeons
Fulbright Senior Research Scholar (Weizmann
Institute, Rehovot, Israel)
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Johnson J, Jones K, Morscher M, Moen S, Klonk C, Jacquet
R, Landis WJ. Gene expression differences in young male
and female ruptured anterior cruciate ligaments. Journal of
Bone and Joint Surgery 2015; 97:71-79.
Shapiro I, Landis W, Risbud MV. Matrix vesicles: Are they
anchored exosomes? Bone 2015; 79:29-36.
Chen L, Jacquet R, Lowder E, Landis WJ. Refinement of
collagen-mineral interaction: A possible role for osteocalcin
in apatite crystal nucleation, growth and development. Bone
2015; 71:7-16.
Grandfield K, Herber R-P, Chen L, Djomehri S, Tam C, Lee
J-H, Brown E, Wolwine III WR, Curtis D, Ryder M, Schuck J,
Webb S, Landis W, Sunita Ho. Strain-guided mineralization
in the bone-PDL-cementum complex of a rat periodontium.
Bone Reports 2015; 3:20-31.
Xu Z, Yang Y, Zhao W, Wang Z, Landis WJ, Cui Q, Sahai N.
Molecular mechanisms for intrafibrillar collagen
mineralization in skeletal tissues. Biomaterials 2015;
39:59-66.