Supplemental Table 1. Symbol Description Fold Regulation 95% CI p-value (comparing to control group) Aimp1 Bmp2 Ccl1 Ccl11 Ccl12 Ccl17 Ccl19 Ccl2 Ccl20 Ccl22 Ccl24 Ccl3 Ccl4 Ccl5 Ccl6 Ccl7 Ccl8 Ccl9 Ccr1 Ccr10 Ccr2 Ccr3 Ccr4 Ccr5 Ccr6 Ccr8 Cd40lg Csf1 Csf2 Csf3 Cx3cl1 Cxcl1 Cxcl10 Cxcl11 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Bone morphogenetic protein 2 Chemokine (C-C motif) ligand 1 Chemokine (C-C motif) ligand 11 Chemokine (C-C motif) ligand 12 Chemokine (C-C motif) ligand 17 Chemokine (C-C motif) ligand 19 Chemokine (C-C motif) ligand 2 Chemokine (C-C motif) ligand 20 Chemokine (C-C motif) ligand 22 Chemokine (C-C motif) ligand 24 Chemokine (C-C motif) ligand 3 Chemokine (C-C motif) ligand 4 Chemokine (C-C motif) ligand 5 Chemokine (C-C motif) ligand 6 Chemokine (C-C motif) ligand 7 Chemokine (C-C motif) ligand 8 Chemokine (C-C motif) ligand 9 Chemokine (C-C motif) receptor 1 Chemokine (C-C motif) receptor 10 Chemokine (C-C motif) receptor 2 Chemokine (C-C motif) receptor 3 Chemokine (C-C motif) receptor 4 Chemokine (C-C motif) receptor 5 Chemokine (C-C motif) receptor 6 Chemokine (C-C motif) receptor 8 CD40 ligand Colony stimulating factor 1 (macrophage) Colony stimulating factor 2 (granulocyte-macrophage) Colony stimulating factor 3 (granulocyte) Chemokine (C-X3-C motif) ligand 1 Chemokine (C-X-C motif) ligand 1 Chemokine (C-X-C motif) ligand 10 Chemokine (C-X-C motif) ligand 11 -1.4472 -1.1181 1.7989 1.0759 1.2597 -1.1455 -1.8632 2.3313 -1.1157 1.0519 -1.4517 5.9746 5.3717 -1.0674 -1.4192 3.013 -1.4642 1.032 -1.3827 -1.4457 -1.3259 -1.5786 1.1102 -1.4311 -1.3183 -1.9357 -2.5617 1.5188 1.6871 1.2302 1.1556 5.4732 1.2838 1.0782 ( 0.47, 0.91 ) ( 0.47, 1.32 ) ( 0.00001, 4.02 ) ( 0.00001, 2.17 ) ( 0.92, 1.60 ) ( 0.32, 1.43 ) ( 0.00001, 1.67 ) ( 1.74, 2.92 ) ( 0.00001, 2.55 ) ( 0.00001, 2.21 ) ( 0.00001, 1.74 ) ( 2.98, 8.97 ) ( 3.43, 7.31 ) ( 0.74, 1.13 ) ( 0.46, 0.95 ) ( 2.26, 3.76 ) ( 0.50, 0.87 ) ( 0.73, 1.34 ) ( 0.60, 0.85 ) ( 0.14, 1.24 ) ( 0.62, 0.88 ) ( 0.52, 0.75 ) ( 0.00001, 2.65 ) ( 0.60, 0.80 ) ( 0.00001, 1.68 ) ( 0.00001, 1.57 ) ( 0.00001, 1.29 ) ( 1.04, 1.99 ) ( 0.29, 3.08 ) ( 0.00001, 2.92 ) ( 0.61, 1.71 ) ( 3.09, 7.85 ) ( 0.94, 1.63 ) ( 0.32, 1.83 ) 0.022703 0.781241 0.389185 0.745817 0.10041 0.820606 0.838649 0.000029 0.998956 0.693855 0.97147 0.000642 0.000108 0.519359 0.037155 0.000001 0.012771 0.70402 0.004033 0.41154 0.010296 0.000452 0.591931 0.00074 0.919529 0.597995 0.935043 0.023942 0.511584 0.729052 0.411437 0.000057 0.059405 0.693417 Cxcl12 Cxcl13 Cxcl15 Cxcl5 Cxcl9 Cxcr2 Cxcr3 Cxcr5 Fasl Ifng Il10ra Il10rb Il11 Il13 Il15 Il16 Il17a Il17b Il17f Il1a Il1b Il1r1 Il1rn Il21 Il27 Il2rb Il2rg Il3 Il33 Il4 Il5 Il5ra Il6ra Il6st Il7 Lta Ltb Mif Nampt Chemokine (C-X-C motif) ligand 12 Chemokine (C-X-C motif) ligand 13 Chemokine (C-X-C motif) ligand 15 Chemokine (C-X-C motif) ligand 5 Chemokine (C-X-C motif) ligand 9 Chemokine (C-X-C motif) receptor 2 Chemokine (C-X-C motif) receptor 3 Chemokine (C-X-C motif) receptor 5 Fas ligand (TNF superfamily, member 6) Interferon gamma Interleukin 10 receptor, alpha Interleukin 10 receptor, beta Interleukin 11 Interleukin 13 Interleukin 15 Interleukin 16 Interleukin 17A Interleukin 17B Interleukin 17F Interleukin 1 alpha Interleukin 1 beta Interleukin 1 receptor, type I Interleukin 1 receptor antagonist Interleukin 21 Interleukin 27 Interleukin 2 receptor, beta chain Interleukin 2 receptor, gamma chain Interleukin 3 Interleukin 33 Interleukin 4 Interleukin 5 Interleukin 5 receptor, alpha Interleukin 6 receptor, alpha Interleukin 6 signal transducer Interleukin 7 Lymphotoxin A Lymphotoxin B Macrophage migration inhibitory factor Nicotinamide phosphoribosyltransferase -1.0975 -1.405 -1.3883 1.1828 -1.6053 -1.1507 -1.757 -1.0888 -1.2059 -2.0012 -1.0123 1.0091 1.3818 1.0258 -1.244 -2.39 -1.4008 -1.0239 3.3176 1.2907 -1.1306 1.145 1.3276 -2.6379 1.1679 -1.2969 -1.0759 -1.7583 -2.7934 -1.0418 2.0915 -1.162 1.0761 1.1108 -1.488 -1.3611 1.0818 -1.0444 1.8436 ( 0.58, 1.24 ) ( 0.24, 1.18 ) ( 0.00001, 2.18 ) ( 0.09, 2.27 ) ( 0.00001, 1.35 ) ( 0.57, 1.16 ) ( 0.41, 0.73 ) ( 0.02, 1.82 ) ( 0.00001, 2.23 ) ( 0.00001, 1.66 ) ( 0.73, 1.25 ) ( 0.76, 1.26 ) ( 0.14, 2.62 ) ( 0.00001, 2.70 ) ( 0.61, 0.99 ) ( 0.31, 0.52 ) ( 0.00001, 1.75 ) ( 0.00001, 2.54 ) ( 1.73, 4.90 ) ( 0.76, 1.82 ) ( 0.68, 1.08 ) ( 0.51, 1.78 ) ( 0.96, 1.69 ) ( 0.00001, 1.28 ) ( 0.44, 1.90 ) ( 0.00001, 1.76 ) ( 0.74, 1.12 ) ( 0.00001, 1.75 ) ( 0.00001, 1.30 ) ( 0.30, 1.62 ) ( 0.00001, 5.63 ) ( 0.00001, 2.46 ) ( 0.71, 1.44 ) ( 0.84, 1.38 ) ( 0.40, 0.94 ) ( 0.00001, 1.87 ) ( 0.41, 1.75 ) ( 0.64, 1.28 ) ( 0.00001, 3.74 ) 0.77432 0.430593 0.922626 0.39249 0.626937 0.447959 0.001025 0.919298 0.854039 0.889855 0.966605 0.86121 0.373482 0.680954 0.070104 0.000187 0.842705 0.797583 0.016831 0.184572 0.285858 0.389924 0.038431 0.886613 0.430716 0.901355 0.514102 0.923033 0.941285 0.783145 0.32033 0.68323 0.498693 0.374393 0.072574 0.770473 0.690821 0.85365 0.330972 Osm Pf4 Spp1 Tnf Tnfrsf11b Tnfsf10 Tnfsf11 Tnfsf13 Tnfsf13b Tnfsf4 Vegfa Gapdh Oncostatin M Platelet factor 4 Secreted phosphoprotein 1 Tumor necrosis factor Tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Tumor necrosis factor (ligand) superfamily, member 10 Tumor necrosis factor (ligand) superfamily, member 11 Tumor necrosis factor (ligand) superfamily, member 13 Tumor necrosis factor (ligand) superfamily, member 13b Tumor necrosis factor (ligand) superfamily, member 4 Vascular endothelial growth factor A Glyceraldehyde-3-phosphate dehydrogenase 5.9444 -1.2869 -1.7252 9.4842 ( 3.86, 8.03 ) ( 0.61, 0.94 ) ( 0.43, 0.73 ) ( 4.36, 14.61 ) 0.000065 0.032745 0.001494 0.037842 1.2758 ( 0.69, 1.87 ) 0.334326 -1.7275 ( 0.38, 0.78 ) 0.00154 -1.3516 ( 0.30, 1.18 ) 0.554994 1.1044 ( 0.79, 1.42 ) 0.355428 -1.3184 -1.3814 1.4525 1 ( 0.30, 1.22 ) ( 0.00001, 1.73 ) ( 0.80, 2.10 ) ( 1.00, 1.00 ) 0.504253 0.994622 0.069471 0
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