FCC-­‐60-­‐00 p.Trp1038* FCC-­‐317-­‐000 p.Gly1121Valfs*3 FCC-­‐681-­‐000 p.Gln60Argfs*7 FCC-­‐905-­‐000 p.Asn1039Ilefs*2 FCC-­‐1322-­‐000 p.Glu650Argfs*13 FCC-­‐1423-­‐000 p.Trp1038* FCC-­‐2104-­‐000 p.Trp1038* FCC-­‐2121-­‐000 p.Gly796* FCC-­‐2431-­‐000 p.Arg175Thrfs*9 FCC-­‐2677-­‐000 p.Trp1038* FCC-­‐3397-­‐000 p.Ser254Ilefs*3 FCC-­‐3527-­‐000 p.Trp1038* FCC-­‐2965-­‐000 p.Arg1086* Breast HAPS-­‐081242 p.Ala995Cysfs*16 Cervical Bilateral breast Unknown 2 39 2 2 2 4 38 46, 70 late 60s [ ] 47 24 2 2 ? Other HAPS-­‐060382 p.Gln66* 40s 61 2 71 ?40s 65 47, 58 50s 50s 3 42 Prostate Bilateral breast Bowel ? 70s 60s Breast 40s 30s 60s 50s 60s 60s HAPS-­‐110583: p.Tyr1183* Stomach Prostate Breast Bowel 80 69 50, 70 80 39 3 2 HAPS-­‐090978: p.Thr193Asnfs*2 9 61 60s 60s Breast Bilateral breast HAPS-­‐100240: p. His1170Phefs*19 AML Ovarian Breast 72 68 36 48 HAPS-­‐110283: p.Trp1038* Ovarian ? Breast Bowel 60 85 57 50s 2 46 5 HAPS-­‐121549: p.Trp1038* Breast ? 50s 56 44 HAPS-­‐114269: p.Pro656Glnfs*11 60s 45 70s 50 3 Br 46 Ov 49 2 Breast 3 2 Unknown primary Ovarian/Prostate 2 HAPS-­‐120953 p.Gln797Hisfs*54 55 62 46 41 Breast 64 NHL Melanoma 55 Bladder HAPS-­‐120272 p.Ser254Ilefs*3 56 3 40s 40s Breast Br 33 Ov 58 Throat 52 50s Ovarian 2 50s Kidney HAPS-­‐090809 p.Gly232Argfs*3 60 3 40 48-­‐50 68 45 41, 47 3 Breast 3 2 Bilateral breast Lung Bowel 2