50000
1-10% allele frequency
range
40000
30000
20000
Counts of sequence
artefacts
Count of sequence artefacts
A
HL-60 Cell line
H-1975 Cell line
4000
2000
0
10000
0
Count of sequence artefacts
B
10-25% allele frequency
range
6000
4000
2000
0
C->A/G->T
T->A/A->T
T->C/A->G
G->C/C->G
G->T/C->A
C->T/G->A