14
A: MiR-187 in BAL vs DLCO
14
B: MiRNA-187 in BAL vs FEV1
12
12
8
10
6
8
miR-187
miRNA-187
10
4
2
y = -16.598x + 17.9
R² = 0.2688
0
0.0%
-2
6
4
50.0%
100.0%
150.0%
2
0
0.0%
-4
-6
miR-3141
y = -12.069x + 15.631
R² = 0.1722
-2
DLCO (% pred)
50.0
45.0
40.0
35.0
30.0
25.0
20.0
15.0
10.0
5.0
0.0
C: miR-3141 in urine vs DLCO ACT
D: miR-548p in urine vs DLCO (% pred)
7
5
4
3
2
y = -9.2974x + 9.4101
R² = 0.2622
1
y = -1.5616x + 33.458
R² = 0.2161
2
4
6
0
-10.0%
20.0%
-2
8
E: miR-574-5p in serum vs RV (% pred)
7
7
6
6
miR-574-5p
miR-574-5p
8
4
60.0%
80.0%
100.0%
120.0%
F: miR-574-5p
in serum vs TLC (% pred)
9
8
5
40.0%
DLCO (% pred)
DLCO ACT
5
4
3
3
y = -4.9928x
+ 9.8499
2
R² = 0.2232
1
y = -2.3776x + 7.206
R² = 0.2623
1
2
0
0.0%
FEV 1 (% pred)
6
0
9
20.0% 40.0% 60.0% 80.0% 100.0% 120.0% 140.0%
50.0%
0
0.0%
100.0%
RV (% pred)
150.0%
200.0%
50.0%
100.0%
TLC (% pred)
150.0%