Title: T-bet and interleukin-27: possible TH1 immunomodulators of sarcoidosis
Article type: Original article
Corresponding author: Wei Sheng Joshua Loke, MB BS VI
First Author: Wei Sheng Joshua Loke, MB BS VI
Order of authors: Joshua Loke1,2, Araluen Freeman1, Linda Garthwaite1, Silvie Prazakova1,2,
Mijeong Park1, Kenneth Hsu1, Paul S. Thomas1,2, and Cristan Herbert1
Author affiliations/location:
1. Inflammation and Infection Research Centre, School of Medical Sciences, UNSW, 2052,
Australia.
2. Department of Respiratory Medicine, Prince of Wales Hospital, Randwick, NSW 2031,
Australia.
Corresponding author:
Wei Sheng Joshua Loke, Department of Respiratory Medicine, Prince of Wales Hospital,
Randwick, NSW 2031, Australia. Inflammation and Infection Research Centre, UNSW
Australia, Sydney, 2052, Australia. Email: [email protected]
([email protected]); Telephone: +61 2 9382 4620; Fax: +61 2 9382 4627
Email address of other authors:
Araluen Freeman
[email protected]
Linda Garthwaite
[email protected]
Silvie Prazakova
[email protected]
Mijeong Park
[email protected]
Kenneth Hsu
[email protected]
Cristan Herbert
[email protected]
Online resource
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Online resource 1: Expression of IFNγ, T-bet and IL-27 mRNA (a-c) in PBMC, and protein
(d-f) in plasma or PBMC cell lysates of sarcoidosis patients according to radiological stage.
Data represented as mean ± SD.
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Online resource 2: Expression of IFNγ, T-bet and IL-27 mRNA (a-c) in PBMC, and in
protein (d-f) in plasma or PBMC cell lysates of sarcoidosis patients according to treatment
status. Data represented as mean ± SD.
C o n c e n t r a t io n o f I L 2 7 ( p g / m l )
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Online resource 3: Comparison of EBC IL-27 concentrations in healthy controls and
sarcoidosis patients. Data represented as mean ± SD.