Shamee Bhattacharjee
Assistant Professor,
Dept. of Zoology,
West Bengal State University.
Berunanpukuria, PO Malikapur, Kolkata-700126.
Telephone: 09831479164 / e-mail: [email protected], [email protected]
EDUCATION
2002-2007
PhD. Cancer Chemoprevention, Chittaranjan National Cancer Institute, Kolkata, India.
2000-2002
MSc in Zoology: University of Calcutta, Ballygunge Science College, Kolkata, India.
EMPLOYMENT
04.04.2009-till date
West Bengal State University.
04.04.2008-03.04.2009
Serampore College
01.11.2006-23.06.2007
Rishi Bankim Chandra College.
01.07.2005-31.10.2006
Dinhata College.
AWARDS & FELLOWSHIPS
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National Scholarship from Govt. of India for performance in BSc (Hons) degree, 2000.
Was a Rank Holder in the Post Graduate examinations, 2002.
Junior Research Fellowship from CSIR-UGC NET, 2003.
Qualified State Level Eligibility Test for Lecturer-ship, 2003.
Selected for the award of CSIR Research Associate in 2008 (File No. 09/030 (0050)/2008EMR-I).
DST Fastrack Award for Young Scientists in 2010.
DBT-CTEP Travel Fellowship for attending Pharma-Nutrition conference held in
Philadelphia, USA in April 2015.
CICS Travel Fellowship for attending Pharma-Nutrition conference held in Philadelphia,
USA in April 2015.
RESEARCH INTERESTS
Elucidating the anti-carcinogenic and chemopreventive potential of natural products such as
spices (both extracts and purified components), traditional medicinal herbs, wild edible fruits and
vegetables in various human cancer cell lines and in vivo murine tumor models and exploring
various signaling pathways to decipher the probable biochemical and molecular mode of action
of these phytochemicals. In future interested to complement and substantiate these laboratory
findings by working with clinical serum and tissue samples.
PEER-REVIEWED PUBLICATIONS IN CHRONOLOGICAL ORDER
1.
Sengupta, A., Ghosh, S., Bhattacharjee, S. and Das, S. (2004) Indian food ingredients and
cancer prevention – an experimental evaluation of anticarcinogenic effects of garlic in rat
colon. Asian Pacific J. Cancer Prevention, 5: 124-130.
2. Sengupta, A., Bhattacharjee, S. and Ghosh, S. (2004) Modulatory influence of Biochanin
A on cyclooxygenase-2 and inducible nitric oxide synthase expression in azoxymethane
induced colonic aberrant crypts. International J. Cancer Prevention, 1(2): 113-121.
3. Sengupta A., Ghosh S., Bhattachrajee S. (2004) Allium Vegetables in Cancer Prevention:
An Overview. Asian Pacific J. cancer Prevention, 5: 237-245.
4. Sengupta A., Ghosh S., Bhattachrajee S. (2005) Dietary Cardamom Inhibits the formation
of Azoxymetahne induced Aberrant crypt foci and reduces COX-2 and iNOS expression in
the colon. Asian Pacific J. cancer Prevention, 6: 118-122.
5. Sengupta, A., Ghosh, S., Das, R. K., Bhattacharjee, S., Bhattacharya, S., (2006)
Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically
induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and
inducible nitric oxide synthase pathways, Eur. J. Cancer Prev., 15, 301-305.
6. Bhattacharjee S., Das I., Rana T., Sengupta A. (2006). Dietary Cinnamon (Cinnmomum
zeylancium) can inhibit the formation of colonic Aberrant Crypt Foci during
experimentally induced colon carcinogenesis in Swiss Albino mice. International J. Cancer
Prevention, Vol 2:5.
7. Rana T, Sengupta A Das I, Bhattacharjee S. (2007). Chemopreventive Efficacy of
Aqueous
Suspension
of Cumin on 7,12-Dimethyl Benz[a] Anthracene Induced Croton
Oil Promoted Skin Carcinogenesis. International J. Cancer Prevention, Vol 3:1/2.
8. Bhattacharjee S., Das I., Rana T., Sengupta A (2007).Inhibition of Lipid peroxidation and
enhancement of GST activity by cardamom and cinnamon during chemically induced
colon carcinogenesis in Swiss albino mice. Asian Pacific J Cancer Prev, 8, 24-26.
9. Bhattacharjee S, Sengupta A (2009) Spices In Cancer Prevention: An Overview.
The
Internet Journal of Nutrition and Wellness.. Volume 7 Number 1.
10. Patra K, Bose S, Sarkar S, Rakshit J, Jana S, Mukherjee A, Roy A, Mandal DP*,
Bhattacharjee S*. Amelioration of cyclophosphamide induced myelosuppression and
oxidative stress by cinnamic acid. Chemico-Biological Interactions 195 (2012) 231–239.
11. Bhattacharjee S* & Mandal DP (2012). Angiogenesis modulation: the "spice effect". J
Environ Pathol Toxicol Oncol. 31(3):273-283.
12. Jana S; Patra K; Sarkar S; Jana J; Mukherjee G; Bhattacharjee S*; Mandal DP* (2014).
Anti-tumorigenic Potential of Linalool is Accompanied by Modulation of Oxidative Stress:
An in vivo Study in Sarcoma-180 Solid Tumor Model. Nutr and Cancer. 66(5): 835-48.
Book Chapter:
1. Rana T, Sengupta A, Das I, Bhattacharjee S, Mondol S (2008). Chemopreventive
Efficacy of Aqueous suspension of Cumin on 7, 12-Dimethylbenz[A]anthracene
induced croton oil promoted skin carcinogenesis. In: Jakobe H Bassiel, Progress in
Cancer Prevention, Nova Science Publishers, pp 81-96.
2. Sengupta A and Bhattacharjee S (2009). Cardamom (Elettaria cardamomum) and Its
Active Constituent, I,8-cineole, in: Aggarwal B and Kunnumakkara A (Eds),
Molecular Targets and therapeutic uses of spices :Modern Uses for Ancient Medicine,
World Scientific Publishing Co., Singapore, pp 65-85.
PATENTS
1. “A cancer chemotherapeutic agent/formulation, manufacture and use thereof”, an
international patent (PCT Int'l Appl. no. PCT/IN2013/000593) for Bose Institute,
Kolkata and West Bengal State University, Barasat, 24 PGS (N). Name of Inventors :
1)DR. SUBHRANGSU CHATTERJEE 2) DR. ANIRBAN BHUNIA 3) DR. DEBA
PRASAD MANDAL 4) DR. SHAMEE BHATTACHARJEE
a. European Phase Patent Application No. 13841638.3 dated 19th March
2015
b. US National Phase Patent Application No. 14428836 dated 17th March
2015
c. Australian National Phase Patent Application No. 2013322120 dated 5th
January 2015
2. Indian patent (1120/KOL/2012 A) entitled “G-QUADRUPLEX STABILIZING
AGENTS AND FORMULATIONS INVOLVING THE SAME”. for Bose Institute,
Kolkata and West Bengal State University, Barasat, 24 PGS (N). Name of Inventors :
1)DR. SUBHRANGSU CHATTERJEE 2) DR. ANIRBAN BHUNIA 3)DR. DEBA
PRASAD MANDAL 4) DR. SHAMEE BHATTACHARJEE
PAPERS PRESENTED IN CONFERENCES
Presented a poster entitled "Mechanism of anti-tumor activity of linalool: pivoting on
differential oxidative stress and angiogenic modulation" at “Pharma-Nutrition 2015” held in
Philadelphia, USA during 13-15th April 2015. Poster was selected for oral presentation in a
session named “Young Investigators Oral Poster presentation”.
RESEARCH PROJECTS
Research Projects as Principal Investigator
Status
Ongoing
(2011-2014)
Title of the Project
Fudging Agency
Modulation of tumor angiogenesis by the use
of active ingredients of Pimpenella anisum
and Coriandrum sativum in mice, a
preclinical study.
Council
for Scientific &
Industrial Research (CSIR),
Govt. of India
Sanction No. Ref No. 37(1487)/1
1/EMR-II
Ongoing
(2012-2015)
An Investigation into the Agrochemicalinduced toxicity in native fishes of the
North24 Parganas district of West Bengal
associated with agricultural run-off events.
Ongoing
(2012-2015)
An Investigation into the Regulation of Nrf2
transcription factor by diosgenin and 1,8cineole using the p53/p21 axis in lung and
leukaemic cancer.
Sanctioned
An investigation into the cross-talk between
transcription factors HIF-1α/2α and Nrf-2
and their modulation by the use of active
ingredients of black pepper (Piper nigrum)
and coriander (Coriandrum sativum).
Department of Science &
Technology (DST), Govt. of
India. under SERC Fast Track
Proposals for Young Scientists
Scheme
Registration. N.o. 0466/2009,
dated 30th June,2010
Indian Council of Medical
Research (ICMR), Govt. of
India.
Letter No. 5/13/49/10/NCD-III,
dated 30-05 -2011
Department of Biotechnology
(DBT), Govt. of India
Research Project as Co-Principal Investigator
Status
Completed
(20112014)
Title of the Project
Funding Agency
Investigation into the modulation of TGFb signaling Department of Biotechnology
by capsaicin and eugenol using the p53/p21 axis in (DBT), Govt. of India.
gastric carcinoma.
Sanction No.
BT/PR15116/GBD/27/327/2011
Ongoing
(20142017)
dated 09/03/2011
Overcoming EGFR resistant Oral Squamous Cell DBT-NER, Govt. of India
Carcinomas with traditional healers of Tripura – A (Twinning Programme 2013-14)
Preclinical Study”
LIST OF COLLABORATORS
Dr. Deba Prasad Mandal, Department of Zoology, West Bengal State University
Dr. Subhragshu Chatterjree, Department of Biophysics, Bose Institute.
Dr. Utpal De , Department of Chemistry, Tripura University
Dr. Gopeswar Mukherjee, Department of Pathology, Barasat District Hospital.
Dr. Anirban Bhunia, Department of Biophysics, Bose Institute.
Dr. Mridu Gupta, Department Dravyaguna (Medicinal plant Pharmacology), Institute of Post
Graduate Ayurvedic Education and Research.
PERSONAL DATA
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DATE OF BIRTH: 14.05.1979
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PLACE OF BIRTH: India.
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LANGUAGES: Bengali, Hindi and English