Stated-Preference Methods
Quarterly Newsletter
Issue 1, July 2014
The project “Advancing stated-preference methods for measuring the
preferences of patients with type 2 diabetes” was funded by PCORI (grant
number 5946). It aims to address gaps in the understanding and applications
of methods to conduct patient centered outcomes research (PCOR) and is
focused on advancing methods for engaging patients and community
stakeholders. The project addresses several key methodological questions
pertaining to the use of stated-preference methods, using type 2 diabetes as a
case study. The research team, led by John F. P. Bridges, is assisted by the
Diabetes Action Board (DAB), a community advisory board of national and
local stakeholders
Community Engagement
Dr. Bridges joined the Steering Committee of the Duchene Muscular Dystrophy FDA Policy Guidance Group,
an initiative led by Parent Project Muscular Dystrophy (PPMD). As part of this group, Dr. Bridges has co-chaired Working
Group # 1, which is producing guidance on Risk-Benefit Analysis as it pertains to Duchene Muscular
Dystrophy. More information about the work of PPMD can be found at http://www.parentprojectmd.org
The Community Research Advisory Council (C-RAC) met with Dr. Bridges on July 21. The C-RAC was established
in 2009 and leads projects that promote trust, understanding and involvement of the Greater Baltimore community in
research activities and educates researchers about community priorities. Five members of the C-RAC currently serve in the
Diabetes Action Board (DAB) as well. At this meeting, the C-RAC gave its feedback on the White Paper on statedpreferences methods that the team developed and encouraged the dissemination of the paper.
Stated-preference Methods
Dr. Bridges is involved as a member of the leadership group of the Conjoint-Analysis Taskforce at the International
Society of Pharmacoeconomics and Outcomes Research (ISPOR). Currently this group is developing guidance of
good research practices for statistical analysis, with the preliminary findings being presented at ISPOR’S annual meeting in
early June in Montreal, Canada. The Center for Health Services and Outcomes Research (CHSOR) here at Hopkins will be
hosting the Taskforce for a consensus meeting August 25-26th. More information can be found at
http://www.ispor.org/TaskForces/Analyzing_Data_Conjoint_Analysis.asp
Dr. Bridges and colleagues from The University of Twente have published a tutorial on the application of Analytic
Hierarchy Process (AHP) in The Patient – Patient-Centered Outcomes Research. AHP is an increasingly common
multiple criteria decision analysis (MCDA) tool that can be used to promote transparent group decision making. The focus
of the tutorial is on benefit-risk assessment of medical technology, and uses a case study of tissue regeneration to repair small
cartilage lesions in the knee. The abstract for the paper is available at http://www.ncbi.nlm.nih.gov/pubmed/24623191
Stated-Preference Methods Newsletter 1, July 2014 1
Patient Centered Outcomes Research
Springer publishing announced that The Patient – Patient-Centered Outcomes Research will be published bimonthly starting in 2015. Dr. Bridges founded The Patient in 2008 to be the first medical publication to exclusively focus on
the patients’ point of view. Since then the journal has developed an international reputation for publishing and advancing
patient-centered outcomes research, including stated-preference methods. More information on the journal can be found at
http://link.springer.com/journal/40271
Dr. Wu is the Johns Hopkins principal investigator of a newly announced randomized trial of a multifactorial fall
injury prevention strategy. Funded by the National Institute on Aging and the Patient Centered Outcomes Research
Institute, the five-year, $30 million study is the largest of its kind. As part of the team, Dr. Wu will co-lead the ten clinical
trial sites which will enroll approximately 6000 patients age 75 or older from primary care practices across the
country. http://www.pcori.org/2014/pcori-and-nih-announce-major-study-of-patient-centered-approach-to-preventingfall-related-injuries-in-older-adults/
Diabetes
The Johns Hopkins Evidence Based Practice Center (directed by Dr. Eric Bass) has received a contract from the Agency for
Healthcare Research and Quality to update their systematic review about the optimal oral medications for
treatment of type 2 diabetes mellitus. Dr. Jodi Segal will provide guidance on the project that will be led by Dr. Shari
Bolen of Case Western University and Dr. Nisa Maruthur of Johns Hopkins. It is expected that this comprehensive review
will be highly informative to patients, clinicians, and guideline developers when completed next year.
Drs. Tanjala Purnell, John Bridges, Jodi Segal and Nisa Maruthur, Susan Joy and Emily Little conducted a systematic
review of published studies using stated-preference method to study type 2 diabetes. This manuscript
provides a comprehensive synthesis of available evidence about how various clinical and quality of life-related factors
influence patient preferences for non-insulin diabetes medications. It identified 61 studies that used various statedpreference methods, including 10 studies that used conjoint analysis. More information about the paper can be found
at http://www.ncbi.nlm.nih.gov/pubmed/24963113.
Research Team Updates
Lila Cummings graduated with a Master of Health Science in Health Economics from the Johns Hopkins Bloomberg
School of Public Health on May 20, 2014. Ms. Cummings’ studies focused on healthcare financing and delivery and she
completed her capstone, “Health disparities & place: a focused investigation of private investment and
primary care physician shortages”. She will continue to work as a research assistant on the PCORI-funded project
“Advancing stated-preference methods for measuring the preferences of patients with type 2 diabetes” through the summer.
Questions? Comments?
Visit our website:
Contact us at the stated preference hotline:
http://www.jhsph.edu/research/affiliated-
(443) 287-1779
programs/stated-preferences/
or email Ellen Janssen:
Join our mailing list:
[email protected]
[email protected]
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