Sup data Table 1A. List of genes identified as up-regulated in the liver of mice fed the LIN diet (rich in
ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_51_P482051
A_55_P2121225
A_51_P355301
A_55_P2001780
A_55_P2028046
A_51_P238576
A_55_P1985623
A_51_P110471
A_55_P2024033
A_51_P319070
A_55_P2389900
A_51_P307168
A_51_P425962
A_55_P1968433
A_55_P1985351
A_55_P2092030
A_55_P1952399
A_55_P2030524
A_55_P1987620
A_55_P2180899
A_52_P543430
A_55_P2038347
A_52_P681391
A_55_P1969128
A_51_P343309
A_51_P369784
A_51_P424532
A_55_P2122464
A_55_P2069907
A_55_P2293013
A_55_P2002578
A_55_P2055442
A_55_P1969131
A_52_P215170
A_55_P2148071
A_52_P574668
A_51_P421846
A_51_P344008
A_52_P535255
A_55_P2002577
A_51_P462918
A_55_P2011111
A_55_P2050628
A_51_P254895
A_55_P1961645
A_51_P287198
A_55_P2054743
A_52_P518808
GeneName
Cyp3a16
Cyp3a11
Cyp3a11
Cyp3a41b
Cyp3a59
Cyp4a14
Abcc3
Ddah1
Cyp4a31
Retsat
Gpr64
Ddah1
Khdrbs3
Agpat9
Slc35f2
Cyp4a10
Cyp4a31
Vldlr
Cyp4a32
Aldh3a2
NAP095541-001
Acot3
G0s2
Cidec
Cmas
Es22
Vnn1
A_55_P2122464
Acot3
Ces6
Ephx1
Pafah2
Cidec
Acot4
LOC673748
Nt5e
Ech1
Slc25a20
Syf2
Ephx1
Ehhadh
Cyp4a10
Cyp4a31
Cyp4a10
Vcp
Krt23
Sh3bgrl2
LOC676546
SystematicName
NM_007820
NM_007818
NM_007818
NM_001105159
NM_001105160
NM_007822
NM_029600
NM_026993
NM_201640
NM_026159
NM_178712
NM_026993
NM_010158
NM_172715
NM_028060
NM_010011
NM_201640
NM_013703
NM_001100181
NM_007437
NAP095541-001
NM_134246
NM_008059
NM_178373
NM_009908
NM_133660
NM_011704
A_55_P2122464
NM_134246
NM_133960
NM_010145
NM_133880
NM_178373
NM_134247
XM_001481151
NM_011851
NM_016772
NM_020520
NM_026780
NM_010145
NM_023737
NM_010011
NM_201640
NM_010011
NM_009503
NM_033373
NM_172507
XM_990990
logFC
2,28
1,99
2,31
2,04
1,40
2,89
1,02
0,64
1,40
0,97
0,51
0,49
0,50
1,04
0,73
1,49
1,33
0,70
1,26
0,84
0,31
1,67
0,84
0,64
0,41
0,65
1,09
0,64
1,15
0,62
0,70
0,27
1,75
0,65
1,59
0,58
0,51
0,41
0,36
0,73
0,77
1,53
1,57
1,52
0,27
1,45
0,44
0,41
tstat
13,32
13,19
12,21
11,76
9,94
8,82
8,51
7,95
7,64
7,24
7,16
7,06
6,92
6,88
6,80
6,78
6,75
6,62
6,47
6,40
6,39
6,27
6,21
6,18
6,16
6,08
6,02
6,01
6,00
5,92
5,84
5,79
5,75
5,67
5,66
5,65
5,64
5,61
5,52
5,52
5,51
5,49
5,39
5,38
5,33
5,32
5,28
5,23
p-value
4,73E-11
5,60E-11
2,07E-10
3,92E-10
6,12E-09
4,01E-08
6,95E-08
1,89E-07
3,42E-07
7,39E-07
8,62E-07
1,04E-06
1,40E-06
1,51E-06
1,76E-06
1,82E-06
1,95E-06
2,55E-06
3,45E-06
4,01E-06
4,11E-06
5,21E-06
5,92E-06
6,29E-06
6,52E-06
7,77E-06
8,78E-06
8,97E-06
9,11E-06
1,08E-05
1,28E-05
1,44E-05
1,57E-05
1,87E-05
1,89E-05
1,95E-05
1,96E-05
2,12E-05
2,56E-05
2,59E-05
2,62E-05
2,76E-05
3,42E-05
3,50E-05
3,92E-05
4,01E-05
4,32E-05
4,89E-05
q-value
4,64E-07
4,64E-07
1,14E-06
1,62E-06
2,03E-05
1,11E-04
1,65E-04
3,49E-04
5,67E-04
1,11E-03
1,19E-03
1,33E-03
1,56E-03
1,57E-03
1,68E-03
1,68E-03
1,70E-03
2,11E-03
2,60E-03
2,83E-03
2,83E-03
3,45E-03
3,77E-03
3,86E-03
3,86E-03
4,15E-03
4,44E-03
4,44E-03
4,44E-03
5,12E-03
5,88E-03
6,43E-03
6,66E-03
7,57E-03
7,57E-03
7,57E-03
7,57E-03
7,97E-03
9,24E-03
9,24E-03
9,24E-03
9,52E-03
1,13E-02
1,14E-02
1,23E-02
1,23E-02
1,25E-02
1,40E-02
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_51_P339540
A_55_P2005213
A_55_P1962214
A_52_P597860
A_51_P352381
A_55_P2107528
A_51_P333111
A_55_P2101776
A_66_P136998
A_51_P243304
A_52_P423174
A_55_P2101191
A_55_P2124619
A_55_P2032946
A_51_P299287
A_55_P2144436
A_55_P1991585
A_55_P2031471
A_51_P327585
A_52_P327156
A_55_P2039044
A_55_P2038362
A_55_P2140646
A_51_P178772
A_55_P2170454
A_55_P1959228
A_52_P35304
A_51_P491227
A_55_P1973844
A_55_P2013765
A_52_P315976
A_52_P220163
A_51_P215077
A_51_P196590
A_55_P2133205
A_52_P655803
A_55_P2121408
A_55_P2074081
A_51_P497061
A_55_P2080880
A_55_P1998656
A_55_P2159189
A_66_P104527
A_55_P2162404
A_55_P2102065
A_52_P590154
A_52_P231635
A_51_P386899
GeneName
Cdkn1c
Ces2
Kpna3
Wasf2
Dhrs4
A_55_P2107528
Aox1
Adora1
Tmem43
Galk1
Acaa1b
Arrdc4
Smurf2
Gsta1
Impa2
Rrp1
Blvrb
Rufy4
Gstm4
0610008F07Rik
Cyp3a59
Acot5
Creg1
AU018778
Gsta2
Slc4a4
Chkb
Suclg1
Sema5b
Raly
Tpm2
5830454E08Rik
Mgst3
Hadh
Nmt2
Chpt1
Tpm2
A_55_P2074081
Ppp2r2d
Clcnkb
Entpd5
Decr1
Tbl1x
LOC100047327
Gm10639
Hsd17b6
Oxsm
Mfsd7c
SystematicName
NM_009876
NM_145603
NM_008466
NM_153423
NM_030686
A_55_P2107528
NM_009676
NM_001008533
NM_028766
NM_016905
NM_146230
NM_025549
NM_025481
NM_008181
NM_053261
NM_010925
NM_144923
NM_001034060
NM_026764
NR_027970
NM_001105160
NM_145444
NM_011804
NM_144930
NM_008182
NM_018760
NM_007692
NM_019879
NM_013661
NM_023130
NM_009416
XM_001473897
NM_025569
NM_008212
NM_008708
NM_144807
NM_009416
A_55_P2074081
NM_026391
NM_019701
NM_001026214
NM_026172
NM_020601
XM_001477908
NM_001122660
NM_013786
NM_027695
NM_145447
logFC
0,34
0,56
0,29
0,36
0,42
0,60
0,57
0,57
0,45
0,42
0,66
0,32
0,37
0,77
0,37
0,40
0,38
0,53
0,46
0,84
0,58
0,99
0,52
0,30
0,94
0,41
0,34
0,24
0,30
0,56
0,85
0,29
0,67
0,29
0,22
0,50
0,95
0,29
0,32
0,27
0,40
0,42
0,26
0,49
0,92
1,03
0,25
0,51
tstat
5,21
5,20
5,17
5,08
5,07
5,06
5,04
5,00
4,99
4,98
4,95
4,92
4,82
4,82
4,78
4,78
4,72
4,69
4,68
4,67
4,67
4,66
4,63
4,63
4,61
4,56
4,56
4,54
4,54
4,53
4,50
4,49
4,47
4,47
4,47
4,46
4,45
4,45
4,42
4,42
4,42
4,40
4,40
4,38
4,36
4,34
4,33
4,33
p-value
5,10E-05
5,20E-05
5,49E-05
6,81E-05
6,98E-05
7,14E-05
7,40E-05
8,16E-05
8,22E-05
8,54E-05
8,96E-05
9,73E-05
1,19E-04
1,21E-04
1,31E-04
1,33E-04
1,52E-04
1,62E-04
1,64E-04
1,67E-04
1,68E-04
1,73E-04
1,84E-04
1,87E-04
1,96E-04
2,16E-04
2,19E-04
2,25E-04
2,28E-04
2,31E-04
2,50E-04
2,55E-04
2,68E-04
2,68E-04
2,68E-04
2,70E-04
2,76E-04
2,77E-04
2,96E-04
2,97E-04
2,98E-04
3,11E-04
3,12E-04
3,27E-04
3,45E-04
3,59E-04
3,63E-04
3,67E-04
q-value
1,43E-02
1,44E-02
1,49E-02
1,73E-02
1,73E-02
1,74E-02
1,78E-02
1,92E-02
1,92E-02
1,96E-02
2,03E-02
2,18E-02
2,58E-02
2,58E-02
2,68E-02
2,70E-02
2,93E-02
3,08E-02
3,08E-02
3,09E-02
3,09E-02
3,15E-02
3,27E-02
3,29E-02
3,38E-02
3,66E-02
3,66E-02
3,70E-02
3,71E-02
3,72E-02
3,95E-02
3,98E-02
3,99E-02
3,99E-02
3,99E-02
3,99E-02
4,03E-02
4,03E-02
4,22E-02
4,22E-02
4,22E-02
4,34E-02
4,34E-02
4,44E-02
4,62E-02
4,73E-02
4,73E-02
4,73E-02
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P1967776
A_52_P1181112
A_52_P515036
A_55_P2125551
A_51_P386612
A_55_P2178800
A_55_P2326260
A_55_P2045036
A_55_P2093770
A_55_P2043892
A_55_P2093705
A_51_P308961
A_55_P2073294
A_52_P316933
A_55_P2069969
A_55_P1970164
A_55_P2178349
A_55_P2005570
A_55_P2009567
A_55_P2454099
A_66_P100565
A_51_P319879
A_51_P350048
A_66_P106760
A_55_P2180744
A_51_P163378
A_65_P11853
A_51_P412225
A_52_P16419
A_55_P2162880
A_66_P137102
A_55_P1960556
A_55_P2170225
A_51_P179919
A_55_P1997951
A_55_P2079516
A_55_P2118391
A_51_P155313
A_55_P2087066
A_55_P2055632
A_51_P383755
A_55_P1972720
A_51_P269792
A_51_P177762
A_51_P229599
A_55_P2005420
A_51_P112223
A_51_P257156
GeneName
Slc4a4
Slc6a16
Htatip2
Mmadhc
Pir
Ugt1a10
4930525G20Rik
Gm6911
A_55_P2093770
Srd5a3
Meig1
Hmgcl
Hadhb
Sh3bgrl2
Gm10639
Rnf11
Ywhaq
Cugbp2
Rod1
Mgea5
RP23-195K8.6
Acadm
Gstt2
Adam32
Clstn3
Zwint
Arhgap28
Tbc1d16
Gpd1
Cyp3a57
6330409N04Rik
Acox1
Sh3bgrl2
Ces5
Htatsf1
Mpp1
Lrp6
Gsto1
Slc25a10
2410001C21Rik
1110006G14Rik
Pmm1
Rad51l1
Rdh9
Etnk1
Gm16439
Gsta4
Ddrgk1
SystematicName
NM_018760
XM_355900
NM_016865
NM_133839
NM_027153
NM_201641
AK029746
XM_893520
A_55_P2093770
NM_020611
NM_008579
NM_008254
NM_145558
NM_172507
NM_001122660
NM_013876
NM_011739
NM_010160
NM_144904
NM_023799
NM_001037913
NM_007382
NM_010361
NM_153397
NM_153508
ENSMUST00000020081
NM_172964
NM_172443
NM_010271
NM_001100180
NM_025697
NM_015729
NM_172507
NM_172759
NM_028242
NM_008621
NM_008514
NM_010362
NM_013770
NM_025542
XM_989766
NM_013872
NM_009014
NM_153133
NM_029250
XM_001478188
NM_010357
NM_029832
logFC
0,41
0,31
0,40
0,27
0,44
0,45
0,49
0,33
0,63
0,25
0,28
0,38
0,31
0,36
0,72
0,27
0,31
0,31
0,26
0,31
0,29
0,43
0,56
0,42
1,02
0,22
0,20
0,34
0,52
0,52
0,26
0,32
0,30
0,24
0,34
0,21
0,23
0,37
0,47
0,53
0,39
0,39
0,83
0,46
0,26
0,30
0,50
0,25
tstat
4,33
4,31
4,31
4,30
4,30
4,30
4,29
4,29
4,27
4,26
4,24
4,23
4,22
4,21
4,21
4,20
4,19
4,19
4,18
4,17
4,17
4,17
4,16
4,16
4,16
4,14
4,13
4,13
4,11
4,09
4,08
4,08
4,06
4,05
4,03
4,01
3,97
3,97
3,97
3,97
3,96
3,96
3,96
3,95
3,95
3,94
3,94
3,93
p-value
3,68E-04
3,78E-04
3,85E-04
3,87E-04
3,93E-04
3,93E-04
3,99E-04
4,00E-04
4,22E-04
4,23E-04
4,44E-04
4,55E-04
4,68E-04
4,77E-04
4,77E-04
4,94E-04
4,97E-04
5,05E-04
5,14E-04
5,21E-04
5,22E-04
5,23E-04
5,31E-04
5,34E-04
5,36E-04
5,64E-04
5,74E-04
5,75E-04
6,04E-04
6,36E-04
6,42E-04
6,51E-04
6,70E-04
6,94E-04
7,24E-04
7,50E-04
8,25E-04
8,32E-04
8,33E-04
8,36E-04
8,44E-04
8,45E-04
8,46E-04
8,61E-04
8,74E-04
8,81E-04
8,96E-04
9,00E-04
q-value
4,73E-02
4,82E-02
4,84E-02
4,84E-02
4,84E-02
4,84E-02
4,84E-02
4,84E-02
4,98E-02
4,98E-02
5,15E-02
5,24E-02
5,35E-02
5,38E-02
5,38E-02
5,42E-02
5,42E-02
5,47E-02
5,49E-02
5,49E-02
5,49E-02
5,49E-02
5,52E-02
5,52E-02
5,52E-02
5,77E-02
5,81E-02
5,81E-02
6,04E-02
6,31E-02
6,33E-02
6,38E-02
6,49E-02
6,69E-02
6,94E-02
7,15E-02
7,45E-02
7,45E-02
7,45E-02
7,45E-02
7,45E-02
7,45E-02
7,45E-02
7,55E-02
7,62E-02
7,64E-02
7,70E-02
7,70E-02
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_51_P464981
A_51_P443618
A_52_P357055
A_55_P2180121
A_55_P2181753
A_51_P445662
A_55_P2179348
A_51_P368496
A_52_P161297
A_52_P526265
A_55_P2056342
A_55_P1980062
A_55_P2025153
A_52_P57622
A_55_P1978596
A_52_P49601
A_55_P2413458
A_55_P2176530
A_52_P57526
A_55_P2003494
A_51_P430563
A_55_P2032740
A_55_P2419514
A_55_P2095859
A_51_P456957
A_66_P136099
A_65_P06446
A_51_P434697
A_55_P2153923
A_55_P1957378
A_52_P480064
A_52_P598714
A_52_P134639
A_51_P386526
A_52_P572197
A_55_P2157019
A_55_P1965416
A_55_P1988368
A_55_P2112549
A_52_P469381
A_52_P631356
A_55_P1990894
A_51_P113784
A_52_P570240
A_52_P339791
A_55_P2087404
A_55_P1967196
A_55_P1999785
GeneName
Map1lc3a
0610011F06Rik
Ccdc91
1300010F03Rik
Bdh1
Hsd17b4
Mapk14
Tmem98
Tcea3
Wdr73
Mgst3
A_55_P1980062
Hmgb1
Acss3
Trit1
Fth1
Tcfcp2l1
1110057K04Rik
Sin3b
NAP071796-1
Mtpn
Iars2
Ccny
ENSMUST00000077287
Pex11a
Coasy
Tfrc
Ube2e2
Slc17a5
Unc119
Tmem134
Afg3l1
Tgoln2
Wbscr16
Pank3
Phb2
Atp9a
Upp1
NAP103155-1
Comtd1
Cobll1
Psmd4
Prpf19
Kbtbd11
Hdgf
Mapre3
Lamb3
Gm14048
SystematicName
NM_025735
NM_026686
NM_025911
NM_173758
NM_001122683
NM_008292
NM_001168514
NM_029537
NM_011542
NM_028026
NM_025569
A_55_P1980062
NM_010439
NM_198636
NM_025873
NM_010239
NM_023755
NM_001167768
NM_001113248
NAP071796-1
NM_008098
NM_198653
NM_026484
ENSMUST00000077287
NM_011068
NM_027896
NM_011638
NM_144839
NM_172773
NM_011676
NM_001078649
NM_054070
NM_009444
NM_033572
NM_145962
NM_007531
NM_015731
NM_009477
NAP103155-1
NM_026965
NM_177025
NM_008951
NM_134129
NM_029116
NM_008231
NM_133350
NM_008484
XR_005128
logFC
0,42
0,21
0,23
0,24
0,35
0,31
0,25
0,27
0,43
0,28
0,71
0,17
0,29
0,39
0,32
0,17
0,32
0,27
0,18
0,29
0,20
0,32
0,49
0,24
0,60
0,24
0,28
0,23
0,25
0,47
0,32
0,23
0,36
0,26
0,22
0,25
0,33
0,35
0,27
0,28
0,22
0,26
0,41
0,53
0,24
0,21
0,52
0,23
tstat
3,93
3,93
3,91
3,91
3,90
3,89
3,87
3,87
3,86
3,86
3,86
3,85
3,85
3,84
3,84
3,84
3,83
3,83
3,82
3,80
3,79
3,79
3,78
3,78
3,77
3,76
3,76
3,75
3,75
3,75
3,73
3,73
3,73
3,73
3,72
3,71
3,70
3,69
3,68
3,68
3,68
3,67
3,66
3,66
3,65
3,64
3,63
3,63
p-value
9,03E-04
9,07E-04
9,43E-04
9,60E-04
9,79E-04
9,86E-04
1,04E-03
1,05E-03
1,06E-03
1,06E-03
1,06E-03
1,08E-03
1,09E-03
1,11E-03
1,11E-03
1,12E-03
1,13E-03
1,13E-03
1,16E-03
1,21E-03
1,24E-03
1,24E-03
1,27E-03
1,27E-03
1,31E-03
1,33E-03
1,34E-03
1,35E-03
1,36E-03
1,36E-03
1,42E-03
1,43E-03
1,44E-03
1,44E-03
1,46E-03
1,50E-03
1,55E-03
1,58E-03
1,60E-03
1,62E-03
1,62E-03
1,65E-03
1,68E-03
1,69E-03
1,71E-03
1,74E-03
1,78E-03
1,78E-03
q-value
7,70E-02
7,70E-02
7,81E-02
7,91E-02
7,99E-02
8,01E-02
8,29E-02
8,29E-02
8,32E-02
8,32E-02
8,32E-02
8,41E-02
8,45E-02
8,50E-02
8,50E-02
8,56E-02
8,56E-02
8,56E-02
8,76E-02
9,06E-02
9,15E-02
9,15E-02
9,23E-02
9,23E-02
9,38E-02
9,50E-02
9,54E-02
9,57E-02
9,57E-02
9,57E-02
9,85E-02
9,87E-02
9,88E-02
9,88E-02
9,91E-02
1,01E-01
1,03E-01
1,05E-01
1,06E-01
1,06E-01
1,06E-01
1,07E-01
1,09E-01
1,09E-01
1,10E-01
1,11E-01
1,12E-01
1,12E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P2054744
A_55_P2039210
A_55_P2052848
A_66_P139460
A_55_P2010672
A_51_P443293
A_55_P2097665
A_55_P2210315
A_55_P2006255
A_55_P2430122
A_55_P2038358
A_51_P445683
A_51_P424878
A_51_P375146
A_51_P126437
A_55_P1985259
A_52_P132165
A_55_P2113466
A_52_P326664
A_55_P1982744
A_51_P246224
A_55_P2094079
A_55_P1970537
A_51_P214107
A_55_P2180201
A_55_P2056241
A_55_P2002859
A_55_P2039038
A_55_P2071601
A_66_P119123
A_51_P259902
A_55_P2156625
A_65_P19149
A_55_P1953758
A_55_P2149821
A_55_P1957593
A_55_P2010008
A_55_P2041360
A_52_P284778
A_55_P2104798
A_55_P1960828
A_51_P365694
A_55_P2095035
A_52_P243599
A_55_P2042923
A_51_P350453
A_55_P1992045
A_55_P2091681
GeneName
Sh3bgrl2
Cpt1b
Mif
Mia3
Kif17
Decr2
Arl4a
1110007L15Rik
Txnip
Ilf2
Acot1
4931406C07Rik
2810405K02Rik
Cd36
Enc1
C2cd3
Hsd17b11
A_55_P2113466
Unc93a
NAP062435-1
Tram2
Terf2ip
Bcl7b
Tbc1d20
Mrpl10
Pdlim5
Aifm2
Zfp664
Ppara
A1cf
Arl6ip5
A_55_P2156625
Nln
Serinc2
Sfrs11
Ino80b
Zfp113
Lrp6
Rae1
LOC100044040
Slc16a13
Rala
Gm1833
Hsd17b12
Sgk2
Pdk4
Msi2
Nudt1
SystematicName
NM_172507
NM_009948
NM_010798
NM_177389
NM_010623
NM_011933
NM_001039515
NM_026269
NM_001009935
NM_026374
NM_012006
NM_133732
NM_025582
NM_007643
NM_007930
NM_001017985
NM_053262
A_55_P2113466
NM_199252
NAP062435-1
NM_177409
NM_020584
NM_009745
NM_024196
NM_026154
NM_019808
NM_153779
NM_001081750
NM_011144
NM_001081074
NM_022992
A_55_P2156625
NM_029447
NM_172702
NM_026989
NM_023547
NM_019747
NM_008514
NM_175112
XM_001480269
NM_172371
NM_019491
XM_129965
NM_019657
NM_013731
NM_013743
NM_054043
NM_008637
logFC
0,36
0,28
0,23
0,33
0,43
0,39
0,39
0,24
0,45
0,22
1,11
0,34
0,50
0,58
0,35
0,21
0,34
0,28
0,40
0,25
0,43
0,21
0,21
0,27
0,21
0,24
0,22
0,29
0,25
0,31
0,36
0,40
0,27
0,41
0,42
0,38
0,33
0,20
0,24
0,24
0,36
0,23
0,48
0,30
0,43
0,45
0,17
0,29
tstat
3,63
3,63
3,63
3,62
3,61
3,61
3,61
3,61
3,60
3,60
3,59
3,59
3,59
3,58
3,58
3,58
3,57
3,57
3,57
3,56
3,56
3,56
3,55
3,54
3,54
3,54
3,54
3,54
3,53
3,53
3,53
3,53
3,52
3,52
3,52
3,52
3,51
3,51
3,50
3,50
3,49
3,49
3,48
3,48
3,48
3,48
3,47
3,45
p-value
1,80E-03
1,81E-03
1,81E-03
1,85E-03
1,86E-03
1,86E-03
1,86E-03
1,86E-03
1,93E-03
1,94E-03
1,95E-03
1,96E-03
1,96E-03
2,00E-03
2,02E-03
2,02E-03
2,05E-03
2,06E-03
2,08E-03
2,09E-03
2,11E-03
2,12E-03
2,18E-03
2,18E-03
2,18E-03
2,18E-03
2,19E-03
2,22E-03
2,25E-03
2,28E-03
2,28E-03
2,28E-03
2,28E-03
2,29E-03
2,30E-03
2,31E-03
2,36E-03
2,37E-03
2,41E-03
2,41E-03
2,46E-03
2,49E-03
2,52E-03
2,53E-03
2,54E-03
2,55E-03
2,57E-03
2,68E-03
q-value
1,13E-01
1,13E-01
1,13E-01
1,13E-01
1,13E-01
1,13E-01
1,13E-01
1,13E-01
1,16E-01
1,16E-01
1,17E-01
1,17E-01
1,17E-01
1,19E-01
1,19E-01
1,19E-01
1,20E-01
1,20E-01
1,21E-01
1,21E-01
1,22E-01
1,22E-01
1,22E-01
1,22E-01
1,22E-01
1,22E-01
1,22E-01
1,23E-01
1,24E-01
1,24E-01
1,24E-01
1,24E-01
1,24E-01
1,24E-01
1,24E-01
1,24E-01
1,27E-01
1,27E-01
1,28E-01
1,28E-01
1,30E-01
1,31E-01
1,31E-01
1,31E-01
1,31E-01
1,31E-01
1,31E-01
1,37E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P2017944
A_55_P2078123
A_51_P520106
A_52_P413502
A_55_P2009604
A_52_P290511
A_55_P2039110
A_55_P2066782
A_55_P2000683
A_55_P2064478
A_55_P2036220
A_51_P103222
A_55_P1959500
A_55_P2063283
A_55_P2047509
A_52_P85983
A_55_P2025702
A_52_P537466
A_52_P652913
A_52_P155708
A_52_P13897
A_55_P2073134
A_55_P2087923
A_51_P208697
A_55_P1962707
A_51_P276943
A_52_P9437
A_51_P220135
A_55_P2117146
A_52_P432570
A_52_P663585
A_51_P135654
A_55_P2146976
A_55_P2117843
A_51_P284665
A_51_P133097
A_51_P510663
A_55_P2030183
A_55_P1994917
A_55_P2117574
A_52_P176737
A_66_P104618
A_55_P1957624
A_55_P2057916
A_51_P182471
A_55_P2025123
A_55_P1966982
A_55_P2004119
GeneName
SystematicName
Etfb
NM_026695
Rora
NM_013646
Adprhl2
NM_133883
2410001C21Rik
NM_025542
ENSMUST00000088356 ENSMUST00000088356
Tstd2
NM_173033
ND2
ENSMUST00000082396
D11Wsu99e
NM_138598
Peci
NM_011868
Cdc27
NM_145436
Chadl
NM_001164320
Slc39a4
NM_028064
Ces5
NM_172759
XM_001001076
XM_001001076
Ufd1l
NM_011672
Mrpl45
NM_025927
C330007P06Rik
NM_029951
Zfp330
NM_145600
D930014E17Rik
NM_020616
Creg1
NM_011804
Hook1
NM_030014
Gm5831
XM_901143
Otud3
NM_028453
Ttl
NM_027192
A_55_P1962707
A_55_P1962707
Gpc1
NM_016696
Psmb3
NM_011971
Nfatc1
NM_016791
Pa2g4
NM_011119
Chdh
NM_175343
Sept10
NM_001024910
Eif4ebp2
NM_010124
Gm7026
XM_001476449
Coasy
NM_027896
Plcb1
U85712
Gm4013
XM_001477379
Supt3h
NM_178652
NAP112908-1
NAP112908-1
Wdr5
NM_080848
Ppih
NM_001110130
Lcorl
NM_178142
ENSMUST00000069762 ENSMUST00000069762
Insig2
NM_178082
Pex5
NM_008995
Cugbp2
NM_010160
ENSMUST00000108317 ENSMUST00000108317
Gsr
NM_010344
A_55_P2004119
A_55_P2004119
logFC
0,23
0,35
0,26
0,30
0,26
0,17
0,17
0,20
0,28
0,17
0,31
0,59
0,39
0,90
0,20
0,25
0,20
0,30
0,23
0,33
0,30
0,18
0,29
0,22
0,27
0,48
0,21
0,18
0,32
0,24
0,31
0,21
0,17
0,26
0,22
0,27
0,23
0,25
0,23
0,24
0,25
0,18
0,48
0,17
0,25
0,29
0,19
0,20
tstat
3,44
3,44
3,43
3,43
3,42
3,42
3,42
3,41
3,40
3,40
3,40
3,40
3,40
3,39
3,39
3,39
3,39
3,39
3,38
3,38
3,38
3,37
3,37
3,37
3,37
3,37
3,36
3,36
3,34
3,34
3,33
3,33
3,32
3,32
3,31
3,31
3,31
3,31
3,31
3,31
3,30
3,30
3,30
3,30
3,29
3,28
3,28
3,28
p-value
2,78E-03
2,78E-03
2,81E-03
2,85E-03
2,88E-03
2,88E-03
2,90E-03
2,96E-03
2,99E-03
3,01E-03
3,01E-03
3,02E-03
3,02E-03
3,07E-03
3,07E-03
3,10E-03
3,11E-03
3,11E-03
3,13E-03
3,15E-03
3,18E-03
3,20E-03
3,22E-03
3,23E-03
3,24E-03
3,27E-03
3,28E-03
3,31E-03
3,46E-03
3,49E-03
3,51E-03
3,57E-03
3,62E-03
3,62E-03
3,70E-03
3,70E-03
3,70E-03
3,71E-03
3,73E-03
3,74E-03
3,76E-03
3,79E-03
3,79E-03
3,80E-03
3,85E-03
3,94E-03
3,96E-03
3,97E-03
q-value
1,40E-01
1,40E-01
1,40E-01
1,42E-01
1,43E-01
1,43E-01
1,43E-01
1,46E-01
1,47E-01
1,47E-01
1,47E-01
1,47E-01
1,47E-01
1,48E-01
1,48E-01
1,49E-01
1,49E-01
1,49E-01
1,49E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,51E-01
1,54E-01
1,55E-01
1,55E-01
1,57E-01
1,58E-01
1,58E-01
1,61E-01
1,61E-01
1,61E-01
1,61E-01
1,61E-01
1,61E-01
1,61E-01
1,62E-01
1,62E-01
1,62E-01
1,63E-01
1,66E-01
1,66E-01
1,66E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P2152014
A_51_P114177
A_55_P2002160
A_51_P164630
A_55_P2162592
A_55_P1978696
A_55_P2178247
A_55_P1991906
A_55_P1958220
A_51_P336952
A_52_P160518
A_55_P1983903
A_55_P1963150
A_55_P1979699
A_55_P2060897
A_51_P438952
A_51_P117109
A_55_P1978236
A_51_P489153
A_55_P2091348
A_51_P490023
A_55_P2156101
A_55_P1981217
A_55_P2010788
A_51_P314701
A_55_P2169259
A_55_P2363030
A_52_P182118
A_55_P2064507
A_52_P657240
A_55_P2096807
A_55_P1971174
A_51_P438805
A_51_P233603
A_55_P2089780
A_55_P2107422
A_55_P1994112
A_52_P436238
A_55_P2024046
A_55_P2029503
A_51_P149455
A_55_P2063312
A_55_P2123802
A_55_P2029366
A_51_P163106
A_55_P2166990
A_55_P2133187
A_51_P130427
GeneName
LOC100044952
1810022C23Rik
Sumo3
Fitm1
Lman2
ENSMUST00000101612
Fam20b
Acadvl
Crebl2
Cryl1
Sfmbt1
Thap4
Creg1
Spop
LOC100047628
Bag4
Ilvbl
Mrps7
Crot
A_55_P2091348
Tubb2a
Skp1a
Aatf
Slc6a9
Cyth1
Cyp3a25
Gm9853
NAP058998-1
Msra
Cdc40
Rbms1
Cd1d2
Txnip
Psma7
Fam54b
Kif21a
Sema5b
Odc1
Slc16a5
Osbpl1a
Acadl
Mgll
A_55_P2123802
Abhd6
Bdh1
Ppcs
A_55_P2133187
Psmd3
SystematicName
XM_001473387
NM_026947
NM_019929
NM_026808
NM_025828
ENSMUST00000101612
NM_145413
NM_017366
NM_177687
NM_030004
NM_019460
NM_025920
NM_011804
NM_025287
XM_001476679
NM_026121
NM_173751
NM_025305
NM_023733
A_55_P2091348
NM_009450
NM_011543
NM_019816
NM_008135
NM_011180
NM_019792
BC022771
NAP058998-1
NM_026322
NM_027879
NM_020296
NM_007640
NM_001009935
NM_011969
NM_029759
NM_001109040
NM_013661
NM_013614
NM_001080934
NM_207530
NM_007381
NM_001166250
A_55_P2123802
NM_025341
NM_175177
NM_026494
A_55_P2133187
NM_009439
logFC
0,23
0,30
0,19
0,67
0,17
0,40
0,20
0,21
0,23
0,39
0,18
0,19
0,48
0,35
0,86
0,22
0,27
0,19
0,47
0,28
0,47
0,21
0,18
0,34
0,15
0,45
0,62
0,23
0,23
0,21
0,22
0,34
0,42
0,19
0,22
0,24
0,46
0,22
0,77
0,17
0,21
0,48
0,31
0,45
0,32
0,17
0,35
0,24
tstat
3,27
3,27
3,27
3,27
3,26
3,26
3,26
3,26
3,25
3,25
3,25
3,24
3,24
3,24
3,23
3,23
3,23
3,22
3,22
3,21
3,21
3,21
3,20
3,20
3,20
3,19
3,19
3,19
3,18
3,18
3,18
3,18
3,17
3,17
3,17
3,16
3,16
3,16
3,16
3,16
3,15
3,15
3,15
3,14
3,14
3,14
3,13
3,13
p-value
4,02E-03
4,04E-03
4,05E-03
4,06E-03
4,11E-03
4,12E-03
4,12E-03
4,15E-03
4,21E-03
4,24E-03
4,24E-03
4,31E-03
4,33E-03
4,34E-03
4,40E-03
4,42E-03
4,45E-03
4,49E-03
4,56E-03
4,60E-03
4,62E-03
4,65E-03
4,70E-03
4,75E-03
4,77E-03
4,87E-03
4,87E-03
4,88E-03
4,90E-03
4,91E-03
4,97E-03
4,99E-03
5,08E-03
5,10E-03
5,12E-03
5,14E-03
5,17E-03
5,19E-03
5,20E-03
5,22E-03
5,28E-03
5,31E-03
5,31E-03
5,41E-03
5,41E-03
5,48E-03
5,48E-03
5,51E-03
q-value
1,68E-01
1,68E-01
1,68E-01
1,68E-01
1,69E-01
1,69E-01
1,69E-01
1,70E-01
1,71E-01
1,72E-01
1,72E-01
1,74E-01
1,74E-01
1,74E-01
1,76E-01
1,76E-01
1,77E-01
1,78E-01
1,80E-01
1,80E-01
1,81E-01
1,82E-01
1,83E-01
1,85E-01
1,85E-01
1,87E-01
1,87E-01
1,87E-01
1,88E-01
1,88E-01
1,89E-01
1,89E-01
1,91E-01
1,91E-01
1,91E-01
1,91E-01
1,91E-01
1,91E-01
1,91E-01
1,92E-01
1,93E-01
1,94E-01
1,94E-01
1,96E-01
1,96E-01
1,97E-01
1,97E-01
1,97E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P1971179
A_55_P2131481
A_55_P2340448
A_51_P229655
A_55_P1998912
A_55_P1994947
A_55_P2313033
A_52_P547662
A_52_P434974
A_51_P325318
A_55_P2001948
A_55_P2077783
A_52_P134381
A_51_P192860
A_55_P1982718
A_55_P2052106
A_52_P136709
A_55_P1991911
A_55_P2114863
A_55_P2083449
A_55_P2026982
A_51_P386270
A_52_P347591
A_55_P2175060
A_55_P2151116
A_52_P478629
A_51_P136441
A_52_P625171
A_52_P467046
A_51_P272283
A_51_P202801
A_55_P2055369
A_55_P2094686
A_66_P135742
A_55_P2122314
A_55_P2115995
A_55_P2076580
A_55_P2068988
A_55_P2149274
A_51_P180001
A_51_P427768
A_52_P304323
A_55_P2032659
A_55_P2110567
A_51_P301215
A_55_P2152049
A_55_P2176753
A_52_P52263
GeneName
Cd1d1
A_55_P2131481
B230114P17Rik
Acsm5
Txnrd2
Gm6097
Ptprb
P2ry1
Ubqln1
Serinc2
Cab39l
Tubb2a-ps2
Psmd12
Hint1
2410001C21Rik
BC049762
Pctp
EG626095
Mgll
6330409N04Rik
2610019F03Rik
Cyp2d12
Ndufa7
Ppapdc1b
Cbara1
Arcn1
Nudt12
Asph
Wdr48
Cmbl
Abcb9
LOC100045699
AK078025
Wdr1
C230096C10Rik
Sms
Acaa1a
Gm5678
Sh3bp5l
Eif2c2
Diap1
Isca1
Tox
Proca1
2310008H09Rik
Xrcc3
LOC640614
D17Wsu92e
SystematicName
NM_007639
A_55_P2131481
AK045415
NM_178758
NM_013711
XM_883948
NM_029928
NM_008772
NM_152234
NM_172702
NM_026908
NR_003964
NM_025894
NM_008248
NM_025542
NM_177567
NM_008796
XM_909743
NM_001166251
NM_025697
NM_173744
NM_201360
NM_023202
NM_028000
NM_144822
NM_145985
NM_026497
NM_133723
NM_026236
NM_181588
NM_019875
XM_001474166
AK078025
NM_011715
NM_146157
NM_009214
NM_130864
XM_487442
NM_001161338
NM_153178
NM_007858
NM_026921
NM_145711
NM_001045516
NM_023197
NM_028875
XM_917662
NM_001044719
logFC
0,28
0,26
0,59
0,20
0,29
0,20
0,19
0,37
0,20
0,42
0,15
0,25
0,26
0,13
0,38
0,17
0,37
0,23
0,41
0,28
0,26
0,18
0,15
0,23
0,21
0,20
0,23
0,23
0,17
0,25
0,24
0,32
0,38
0,15
0,15
0,17
0,25
0,26
0,18
0,25
0,20
0,21
0,42
0,33
0,29
0,27
0,21
0,33
tstat
3,13
3,13
3,13
3,11
3,11
3,10
3,10
3,10
3,10
3,10
3,09
3,08
3,08
3,07
3,07
3,07
3,07
3,06
3,06
3,06
3,05
3,04
3,04
3,04
3,04
3,04
3,04
3,04
3,03
3,03
3,03
3,02
3,02
3,02
3,02
3,02
3,01
3,01
3,01
3,01
3,01
3,01
3,00
3,00
3,00
3,00
2,99
2,99
p-value
5,53E-03
5,55E-03
5,57E-03
5,73E-03
5,85E-03
5,90E-03
5,92E-03
5,94E-03
5,94E-03
5,95E-03
5,99E-03
6,20E-03
6,23E-03
6,30E-03
6,35E-03
6,36E-03
6,39E-03
6,41E-03
6,46E-03
6,49E-03
6,61E-03
6,74E-03
6,77E-03
6,78E-03
6,79E-03
6,81E-03
6,82E-03
6,83E-03
6,90E-03
6,96E-03
6,99E-03
7,01E-03
7,04E-03
7,09E-03
7,11E-03
7,15E-03
7,18E-03
7,19E-03
7,20E-03
7,28E-03
7,29E-03
7,29E-03
7,40E-03
7,40E-03
7,44E-03
7,47E-03
7,54E-03
7,54E-03
q-value
1,97E-01
1,97E-01
1,97E-01
2,00E-01
2,04E-01
2,05E-01
2,05E-01
2,05E-01
2,05E-01
2,05E-01
2,05E-01
2,11E-01
2,11E-01
2,13E-01
2,14E-01
2,14E-01
2,14E-01
2,14E-01
2,15E-01
2,15E-01
2,18E-01
2,21E-01
2,21E-01
2,21E-01
2,21E-01
2,21E-01
2,21E-01
2,21E-01
2,23E-01
2,24E-01
2,24E-01
2,25E-01
2,25E-01
2,26E-01
2,26E-01
2,27E-01
2,27E-01
2,27E-01
2,27E-01
2,28E-01
2,28E-01
2,28E-01
2,30E-01
2,30E-01
2,31E-01
2,31E-01
2,32E-01
2,32E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_55_P2119257
A_55_P1959703
A_55_P2119155
A_52_P685999
A_55_P1977776
A_55_P1965154
A_51_P478003
A_55_P1994020
A_51_P125368
A_55_P1953608
A_55_P2176325
A_66_P110798
A_52_P5549
A_52_P50287
A_51_P105589
A_55_P2462377
A_55_P2043762
A_55_P2043531
A_55_P2032478
A_51_P513992
A_52_P38157
A_55_P2095578
A_52_P654752
A_55_P2113912
A_52_P658974
A_55_P1977875
A_66_P140507
A_55_P2169135
A_55_P2013701
A_55_P2093023
A_52_P75384
A_55_P1970806
A_55_P1973838
A_55_P2184741
A_55_P2117579
A_55_P2039284
A_51_P308681
A_51_P165060
A_55_P2062589
A_55_P2063251
A_51_P150710
A_52_P163515
A_52_P652212
A_55_P2100770
A_55_P1991239
A_55_P2033605
A_55_P2004333
A_55_P2129219
GeneName
Serpine1
Tubb2c-ps1
Set
Mettl7b
LOC790956
Spc25
Papolg
Casc4
Hars
A_55_P1953608
Prex1
AK145507
Fam133b
Bend7
Dci
Nsf
N6amt1
A_55_P2043531
ENSMUST00000113788
Spag4
Lypla1
Spata5l1
Trub1
Gm5473
Gm5396
Arglu1
Lhpp
NAP113691-1
Ttpa
Xrcc6bp1
B230219D22Rik
Gm16379
Slc6a9
Katnal1
Ppih
Hspb1
Ccdc90a
Slc22a5
Mtnr1a
Dusp3
Igj
NAP112224-1
Psmd14
Usp48
ENSMUST00000061906
9430038I01Rik
Rpl24
NAP113071-1
SystematicName
NM_008871
XM_001473123
NM_023871
NM_027853
NR_003280
NM_025565
NM_172555
NM_177054
NM_008214
A_55_P1953608
NM_177782
AK145507
NM_001042501
NM_178663
NM_010023
NM_008740
NM_026366
A_55_P2043531
ENSMUST00000113788
NM_139151
NM_008866
XM_001481333
NM_029839
XM_484474
XM_358238
NM_176849
NM_029609
NAP113691-1
NM_015767
NM_026858
NM_181278
NM_001111330
NM_008135
NM_153572
NM_001110129
NM_013560
NM_001081059
NM_011396
NM_008639
NM_028207
NM_152839
NAP112224-1
NM_021526
NM_130879
ENSMUST00000061906
ENSMUST00000117404
NM_024218
NAP113071-1
logFC
0,47
0,36
0,19
0,22
0,51
0,34
0,13
0,15
0,21
0,15
0,16
0,46
0,24
0,23
0,37
0,21
0,19
0,26
0,18
0,14
0,21
0,15
0,16
0,25
0,24
0,20
0,20
0,21
0,27
0,19
0,23
0,18
0,35
0,19
0,17
0,51
0,15
0,44
0,33
0,30
0,44
0,27
0,26
0,18
0,24
0,22
0,12
0,19
tstat
2,99
2,99
2,98
2,98
2,98
2,98
2,98
2,97
2,97
2,97
2,97
2,97
2,96
2,96
2,96
2,96
2,95
2,95
2,95
2,95
2,95
2,94
2,94
2,94
2,94
2,93
2,93
2,93
2,93
2,92
2,92
2,92
2,92
2,92
2,92
2,90
2,90
2,90
2,90
2,90
2,89
2,89
2,89
2,88
2,88
2,88
2,88
2,88
p-value
7,57E-03
7,60E-03
7,65E-03
7,70E-03
7,71E-03
7,72E-03
7,77E-03
7,84E-03
7,85E-03
7,90E-03
7,90E-03
7,97E-03
8,02E-03
8,12E-03
8,14E-03
8,15E-03
8,18E-03
8,26E-03
8,27E-03
8,29E-03
8,33E-03
8,44E-03
8,49E-03
8,49E-03
8,51E-03
8,55E-03
8,64E-03
8,68E-03
8,71E-03
8,81E-03
8,84E-03
8,84E-03
8,88E-03
8,88E-03
8,91E-03
9,16E-03
9,19E-03
9,24E-03
9,26E-03
9,31E-03
9,43E-03
9,44E-03
9,45E-03
9,54E-03
9,55E-03
9,56E-03
9,58E-03
9,62E-03
q-value
2,32E-01
2,32E-01
2,33E-01
2,34E-01
2,34E-01
2,34E-01
2,35E-01
2,36E-01
2,36E-01
2,36E-01
2,36E-01
2,37E-01
2,37E-01
2,39E-01
2,39E-01
2,39E-01
2,40E-01
2,42E-01
2,42E-01
2,42E-01
2,43E-01
2,45E-01
2,45E-01
2,45E-01
2,45E-01
2,45E-01
2,47E-01
2,48E-01
2,48E-01
2,51E-01
2,51E-01
2,51E-01
2,51E-01
2,51E-01
2,51E-01
2,58E-01
2,58E-01
2,59E-01
2,59E-01
2,59E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,61E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_66_P106133
A_51_P407904
A_55_P1983459
A_52_P240796
A_66_P134704
A_55_P2074174
A_52_P125550
A_51_P461067
A_55_P2098335
A_55_P1962284
A_55_P2019254
A_55_P1973699
A_51_P168524
A_52_P509710
A_51_P256304
A_52_P205789
A_55_P1980237
A_52_P679101
A_51_P334308
A_55_P2058359
A_52_P568805
A_55_P2109712
A_55_P2010768
A_55_P2057686
A_52_P570652
A_55_P2095271
A_55_P2029732
A_55_P2094100
A_51_P402435
A_55_P2058628
A_51_P345110
A_51_P427232
A_51_P411728
A_66_P134690
A_51_P249793
A_55_P1966432
A_55_P1994694
A_55_P2001903
A_51_P391926
A_55_P2337138
A_51_P407774
A_55_P2047788
A_52_P18807
A_55_P1973723
A_55_P1975052
A_52_P541270
A_55_P2138257
A_55_P2457912
GeneName
Magi3
Trappc4
Cflar
Rdh16
Gm4952
Cpt2
Rhod
ENSMUST00000103420
Map2k4
Klhl24
A_55_P2019254
Htra2
ENSMUST00000101245
Zwint
Mrpl37
Unc119b
Acad11
Tjp2
Tspan14
H2afy
Ubxn1
Csnk1g2
Dpm3
Cdc42ep5
Flywch1
Pkn3
C730027H18Rik
BC085271
Trap1
Hnrnpa3
Thap4
Scand3
2900026A02Rik
Spin1
Dusp28
Gstm1
Serinc2
2010107H07Rik
Ubxn6
1110029L17Rik
Slc22a21
Katnal1
Eif3c
Etfdh
Amt
Crebl2
Ube2d2
Psme4
SystematicName
NM_133853
NM_021789
NM_207653
NM_009040
NM_001013762
NM_009949
NM_007485
ENSMUST00000103420
NM_009157
NM_029436
A_55_P2019254
NM_019752
ENSMUST00000101245
NM_025635
NM_025500
NM_175352
NM_175324
NM_011597
NM_145928
NM_012015
NM_146093
NM_134002
NM_026767
NM_021454
NM_153791
NM_153805
XM_001473569
NM_001008551
NM_026508
NM_198090
NM_025920
NM_183088
NM_172884
NM_146043
NM_175118
NM_010358
NM_172702
NR_024069
NM_024432
AK003962
NM_019723
NM_153572
NM_146200
NM_025794
NM_001013814
NM_177687
NM_019912
NM_134013
logFC
0,23
0,20
0,13
0,49
0,48
0,24
0,30
0,72
0,25
0,22
0,25
0,18
0,15
0,20
0,19
0,17
0,28
0,21
0,16
0,24
0,21
0,15
0,13
0,33
0,25
0,20
0,15
0,20
0,15
0,24
0,13
0,22
0,17
0,25
0,23
0,39
0,34
0,19
0,19
0,19
0,23
0,20
0,30
0,26
0,21
0,20
0,13
0,21
tstat
2,88
2,87
2,87
2,87
2,87
2,86
2,86
2,85
2,85
2,85
2,85
2,85
2,85
2,84
2,84
2,84
2,84
2,84
2,83
2,83
2,83
2,83
2,83
2,83
2,82
2,82
2,82
2,82
2,81
2,81
2,80
2,80
2,80
2,80
2,80
2,80
2,80
2,80
2,79
2,79
2,79
2,79
2,79
2,78
2,78
2,78
2,78
2,78
p-value
9,73E-03
9,75E-03
9,76E-03
9,78E-03
9,94E-03
1,01E-02
1,01E-02
1,02E-02
1,02E-02
1,02E-02
1,03E-02
1,03E-02
1,03E-02
1,05E-02
1,05E-02
1,05E-02
1,05E-02
1,06E-02
1,07E-02
1,08E-02
1,08E-02
1,08E-02
1,08E-02
1,08E-02
1,09E-02
1,09E-02
1,09E-02
1,11E-02
1,12E-02
1,12E-02
1,14E-02
1,14E-02
1,14E-02
1,14E-02
1,15E-02
1,15E-02
1,15E-02
1,15E-02
1,16E-02
1,17E-02
1,17E-02
1,17E-02
1,18E-02
1,19E-02
1,19E-02
1,20E-02
1,20E-02
1,21E-02
q-value
2,62E-01
2,63E-01
2,63E-01
2,63E-01
2,67E-01
2,69E-01
2,69E-01
2,70E-01
2,70E-01
2,70E-01
2,71E-01
2,71E-01
2,71E-01
2,73E-01
2,73E-01
2,73E-01
2,73E-01
2,74E-01
2,76E-01
2,76E-01
2,76E-01
2,76E-01
2,76E-01
2,77E-01
2,77E-01
2,77E-01
2,77E-01
2,80E-01
2,81E-01
2,82E-01
2,84E-01
2,85E-01
2,85E-01
2,85E-01
2,85E-01
2,85E-01
2,85E-01
2,85E-01
2,86E-01
2,86E-01
2,86E-01
2,86E-01
2,88E-01
2,89E-01
2,89E-01
2,90E-01
2,90E-01
2,91E-01
Sup data Table 1A (continued). List of genes identified as up-regulated in the liver of mice fed the LIN diet
(rich in ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_52_P613808
A_55_P2069714
A_51_P380750
A_51_P272563
A_66_P127024
A_55_P2180425
A_55_P2007733
A_51_P401964
A_55_P2151817
A_51_P156955
A_55_P2183032
A_55_P2172892
A_55_P2104597
A_51_P210143
A_55_P2137494
A_66_P130960
GeneName
Zbtb7a
Sqstm1
Cbfa2t3
Naa25
Mbd3
Uqcc
Epn1
Aph1a
Chdh
Cfd
Gm3217
1700080G18Rik
Kctd9
Syne2
A_55_P2137494
Psmd11
SystematicName
NM_010731
NM_011018
NM_009824
NM_172722
NM_013595
NM_018888
NM_010147
NM_146104
NM_001136240
NM_013459
XM_001476004
XM_001000195
NM_001111028
NM_001005510
A_55_P2137494
NM_178616
logFC
0,40
0,27
0,21
0,16
0,20
0,18
0,15
0,16
0,16
2,10
0,30
0,14
0,17
0,33
0,15
0,21
tstat
2,77
2,77
2,77
2,77
2,77
2,76
2,76
2,76
2,76
2,76
2,76
2,75
2,75
2,75
2,75
2,75
p-value
1,22E-02
1,22E-02
1,22E-02
1,22E-02
1,24E-02
1,24E-02
1,25E-02
1,25E-02
1,25E-02
1,26E-02
1,26E-02
1,26E-02
1,27E-02
1,27E-02
1,28E-02
1,28E-02
q-value
2,92E-01
2,92E-01
2,92E-01
2,92E-01
2,95E-01
2,95E-01
2,96E-01
2,96E-01
2,96E-01
2,96E-01
2,96E-01
2,96E-01
2,97E-01
2,97E-01
2,98E-01
2,98E-01
All genes with q-value<0.3 are provided. Genes in grey have q-value<0.05 and were used for plotting
heatmap and for functional categories (GO and KEGG) enrichment tests. Differentially expressed genes
were identified using the limma package of Bioconductor (www.bioconductor.org).
ProbeName: Unique identifier for Agilent Probe; GeneName: Gene symbol; SystematicName: Sequence
accession number; logFC: log2 fold change for LIN group vs PALM group; tstat: limma moderated tstatistic for LIN group vs PALM group; p-value: corresponding raw p-value; q-value: corresponding q-value
(to be used for filtering results based on FDR threshold).
Sup data Table 1B. List of genes identified as down-regulated in the liver of mice fed the LIN diet (rich in
ALA) compared to mice fed the PALM diet (rich in SFA).
ProbeName
A_51_P336325
A_51_P134142
A_55_P2100928
A_51_P480233
A_51_P141546
A_51_P456208
A_51_P381618
A_66_P110633
A_52_P2710
A_51_P479230
A_55_P1995243
A_51_P452768
A_51_P155323
A_55_P1977144
A_66_P108019
A_52_P197402
A_52_P18765
A_51_P137336
A_55_P2067518
A_51_P262701
A_51_P299805
A_52_P84027
A_55_P2132147
A_55_P2032272
A_55_P2077501
A_55_P2112637
A_55_P2058433
A_55_P2026270
A_55_P2043367
A_55_P1984976
A_55_P2095325
A_55_P1971074
A_55_P1971076
A_52_P119060
A_55_P1956862
A_55_P2150179
A_52_P257502
A_55_P1986341
A_55_P1960331
A_55_P2024679
A_51_P365516
A_55_P1988899
A_52_P147803
A_55_P2079713
A_55_P1985428
A_55_P1978502
A_51_P128876
A_55_P2002757
GeneName
SystematicName
Orm1
NM_008768
Cyp2c70
NM_145499
Ptgds
NM_008963
Nmral1
NM_026393
Orm2
NM_011016
Tff3
NM_011575
Pla1a
NM_134102
Apol9b
NM_001168660
Cml5
NM_023493
Nat8
NM_023455
Cobl
NM_172496
Cyp4f14
NM_022434
Hc
NM_010406
Cyp2c67
NM_001024719
Heatr1
NM_144835
Tbc1d30
NM_029057
Hsbp1l1
NM_001136181
Cdh1
NM_009864
Slc13a3
NM_054055
Cpb2
NM_019775
Slc46a3
NM_027872
Cyp7a1
NM_007824
ND3
ENSMUST00000082411
Habp2
NM_146101
Gm6940
XM_901095
ENSMUST00000078284 ENSMUST00000078284
Cyp2c68
NM_001039555
Cfi
NM_007686
Apol9a
NM_173786
Wnt5b
NM_009525
AI182371
NM_178885
Atp11a
NM_015804
Atp11a
NM_015804
Acpp
NM_207668
Egfr
NM_007912
Gm5077
NM_173864
Igfbp4
NM_010517
Gm4956
NR_002858
Srbd1
NM_030133
ENSMUST00000099399 ENSMUST00000099399
Spink3
NM_009258
Mblac2
NM_028372
AI428936
NM_153577
Gramd1c
NM_153528
Atg16l2
NM_001111111
H2-Q1
NM_010390
Ifitm3
NM_025378
Blnk
NM_008528
logFC
-1,09
-0,66
-0,68
-0,42
-1,09
-2,11
-0,41
-0,47
-0,84
-0,97
-0,58
-0,37
-0,42
-0,35
-0,34
-0,40
-0,59
-0,41
-0,56
-0,34
-0,61
-0,91
-0,35
-0,40
-0,35
-0,36
-0,43
-0,23
-0,45
-0,48
-0,39
-0,54
-0,46
-0,53
-0,55
-0,29
-0,23
-0,75
-0,31
-0,41
-0,49
-0,29
-0,55
-0,38
-0,60
-0,91
-0,35
-0,87
tstat
-8,01
-6,91
-6,50
-6,11
-6,11
-5,75
-5,41
-5,36
-5,31
-5,29
-5,13
-5,09
-5,08
-5,07
-4,84
-4,82
-4,79
-4,78
-4,75
-4,74
-4,72
-4,65
-4,62
-4,57
-4,54
-4,50
-4,48
-4,46
-4,39
-4,38
-4,35
-4,33
-4,29
-4,28
-4,27
-4,26
-4,21
-4,20
-4,19
-4,18
-4,11
-4,07
-4,01
-4,00
-3,99
-3,99
-3,99
-3,98
p-value
1,72E-07
1,41E-06
3,23E-06
7,22E-06
7,33E-06
1,56E-05
3,30E-05
3,65E-05
4,10E-05
4,24E-05
6,02E-05
6,63E-05
6,72E-05
6,97E-05
1,16E-04
1,21E-04
1,29E-04
1,31E-04
1,40E-04
1,43E-04
1,51E-04
1,75E-04
1,88E-04
2,11E-04
2,25E-04
2,48E-04
2,61E-04
2,69E-04
3,22E-04
3,24E-04
3,46E-04
3,68E-04
3,98E-04
4,08E-04
4,15E-04
4,31E-04
4,81E-04
4,91E-04
4,98E-04
5,14E-04
6,05E-04
6,64E-04
7,55E-04
7,80E-04
7,90E-04
7,92E-04
7,97E-04
8,11E-04
q-value
3,49E-04
1,56E-03
2,55E-03
4,05E-03
4,05E-03
6,66E-03
1,12E-02
1,16E-02
1,23E-02
1,25E-02
1,61E-02
1,73E-02
1,73E-02
1,73E-02
2,56E-02
2,58E-02
2,68E-02
2,68E-02
2,80E-02
2,82E-02
2,93E-02
3,15E-02
3,29E-02
3,61E-02
3,70E-02
3,95E-02
3,99E-02
3,99E-02
4,44E-02
4,44E-02
4,62E-02
4,73E-02
4,84E-02
4,90E-02
4,94E-02
5,03E-02
5,38E-02
5,42E-02
5,42E-02
5,49E-02
6,04E-02
6,47E-02
7,15E-02
7,35E-02
7,37E-02
7,37E-02
7,38E-02
7,45E-02
Sup data Table 1B (continued). List of genes identified as down-regulated in the liver of mice fed the LIN
diet (rich in ALA) compared to mice fed the PALM diet (rich in SFA)..
ProbeName
A_51_P502119
A_51_P497985
A_55_P2126572
A_52_P240712
A_51_P400366
A_55_P1961014
A_66_P137943
A_55_P2131766
A_51_P290626
A_52_P682382
A_51_P154842
A_52_P362111
A_55_P1989215
A_52_P674467
A_52_P504361
A_51_P353895
A_55_P2032294
A_51_P349727
A_51_P113205
A_51_P255295
A_55_P2397599
A_55_P1954116
A_55_P2144636
A_55_P1969904
A_55_P2135551
A_55_P2106844
A_55_P2061273
A_55_P2303868
A_55_P1962661
A_52_P550147
A_55_P1952071
A_55_P1967591
A_52_P235102
A_52_P127325
A_55_P2101944
A_55_P2082215
A_55_P2122841
A_66_P138289
A_55_P2347756
A_51_P198434
A_55_P1953387
A_51_P101545
A_55_P1972297
A_55_P2141306
A_55_P2116305
A_52_P512553
A_51_P311958
A_55_P2026233
GeneName
SystematicName
F11
NM_028066
C2
NM_013484
Tmem25
NM_027865
Cml2
NM_053096
Rhbg
NM_021375
Selenbp1
NM_009150
Tctn2
NM_026486
D4Wsu53e
NM_023665
Gulo
NM_178747
Scd1
NM_009127
Oas1f
NM_145153
Fam3c
NM_138587
Entpd8
NM_028093
Lin7a
NM_001039354
Naglu
NM_013792
Sult1c2
NM_026935
ENSMUST00000112536 ENSMUST00000112536
Slc25a45
NM_134154
F13b
NM_031164
C9
NM_013485
B930025B16Rik
AK047130
C8b
NM_133882
Ccdc163
NM_026714
Abcc6
NM_018795
Dnase1l2
NM_025718
Gm7475
XM_001476912
Tbx6
NM_011538
5033421B08Rik
AK050516
Cyp2c67
NM_001024719
Sned1
ENSMUST00000062202
Npb
NM_153288
LOC100044615
XM_001472709
Gm5595
NM_001008427
AI182371
NM_178885
Gm9444
XM_001479912
Ttbk1
NM_001162864
NAP114472-1
NAP114472-1
Rdh5
NM_134006
AU040972
BG080322
H2-K1
NM_001001892
Fabp5
NM_010634
Hgfac
NM_019447
Plk5
NM_183152
Synj2bp
NM_025292
Tnfrsf25
NM_033042
Atg16l2
NM_001111111
Orm3
NM_013623
Uba7
NM_023738
logFC
-0,44
-0,31
-0,42
-0,34
-0,49
-0,46
-0,23
-0,37
-0,35
-0,87
-0,40
-0,45
-0,27
-0,30
-0,31
-0,66
-0,21
-0,30
-0,25
-0,39
-0,25
-0,51
-0,31
-0,28
-0,17
-0,34
-0,21
-0,43
-0,40
-0,32
-0,28
-0,37
-0,17
-0,25
-0,37
-0,31
-1,31
-0,35
-0,46
-0,19
-1,25
-0,31
-0,20
-0,26
-0,19
-0,40
-0,93
-0,33
tstat
-3,96
-3,92
-3,92
-3,92
-3,92
-3,90
-3,89
-3,88
-3,88
-3,81
-3,79
-3,79
-3,78
-3,78
-3,74
-3,74
-3,72
-3,70
-3,70
-3,70
-3,66
-3,65
-3,64
-3,63
-3,61
-3,60
-3,55
-3,55
-3,55
-3,54
-3,53
-3,51
-3,50
-3,50
-3,48
-3,47
-3,47
-3,45
-3,45
-3,44
-3,39
-3,38
-3,37
-3,37
-3,37
-3,37
-3,36
-3,35
p-value
8,45E-04
9,18E-04
9,20E-04
9,21E-04
9,38E-04
9,67E-04
9,93E-04
1,01E-03
1,02E-03
1,18E-03
1,24E-03
1,25E-03
1,28E-03
1,28E-03
1,38E-03
1,40E-03
1,45E-03
1,52E-03
1,52E-03
1,54E-03
1,69E-03
1,73E-03
1,75E-03
1,82E-03
1,86E-03
1,93E-03
2,13E-03
2,15E-03
2,17E-03
2,18E-03
2,26E-03
2,36E-03
2,40E-03
2,43E-03
2,50E-03
2,56E-03
2,56E-03
2,69E-03
2,71E-03
2,74E-03
3,12E-03
3,17E-03
3,23E-03
3,26E-03
3,27E-03
3,27E-03
3,30E-03
3,35E-03
q-value
7,45E-02
7,71E-02
7,71E-02
7,71E-02
7,81E-02
7,93E-02
8,02E-02
8,15E-02
8,15E-02
8,86E-02
9,15E-02
9,19E-02
9,23E-02
9,23E-02
9,67E-02
9,77E-02
9,91E-02
1,02E-01
1,02E-01
1,03E-01
1,09E-01
1,10E-01
1,11E-01
1,13E-01
1,13E-01
1,16E-01
1,22E-01
1,22E-01
1,22E-01
1,22E-01
1,24E-01
1,27E-01
1,28E-01
1,28E-01
1,31E-01
1,31E-01
1,31E-01
1,37E-01
1,37E-01
1,38E-01
1,49E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,50E-01
1,51E-01
1,52E-01
Sup data Table 1B (continued). List of genes identified as down-regulated in the liver of mice fed the LIN
diet (rich in ALA) compared to mice fed the PALM diet (rich in SFA)..
ProbeName
A_51_P506328
A_51_P204247
A_55_P2150976
A_52_P308465
A_55_P2300913
A_55_P2137521
A_55_P1984098
A_51_P114634
A_52_P467861
A_51_P400016
A_55_P2098734
A_55_P2114953
A_55_P2120706
A_55_P2025343
A_55_P1990505
A_52_P611798
A_55_P1956863
A_51_P280437
A_52_P231292
A_51_P499169
A_55_P1981830
A_55_P2005783
A_51_P214747
A_55_P2000521
A_52_P123485
A_51_P193336
A_55_P1964359
A_55_P2096043
A_51_P122582
A_55_P2148935
A_55_P2035265
A_55_P2019690
A_51_P384318
A_55_P2079659
A_51_P253547
A_52_P284889
A_51_P108226
A_55_P2010332
A_55_P1991199
A_55_P2105100
A_52_P1092823
A_55_P2078633
A_55_P2023703
A_51_P487690
A_55_P2138739
A_52_P237077
A_52_P745
A_51_P378699
GeneName
Cyp2j6
C8a
Fabp5l2
Plxnb1
D130095D21Rik
Nmral1
Mst1
Amz1
Prhoxnb
ENSMUST00000114964
Ttc21b
Usp18
A_55_P2120706
Mup21
Masp2
Ddx5
Egfr
Slc12a6
Cyp2j6
Tram1
LOC100041203
Ifih1
Parp12
Lonrf1
Tcf25
Nucb2
Cnot8
Acot11
Daglb
LOC100040286
Trpm7
Slc43a1
C1ra
Dnase2b
Ctsl
Prkcz
1100001G20Rik
Ewsr1
Nos1ap
Lrig1
Irx1
C4b
Zfp386
Ifi44
LOC100039570
Esr1
Acox3
Sohlh2
SystematicName
NM_010008
NM_146148
XM_886827
NM_172775
AK084110
NM_026393
NM_008243
NM_173405
NM_001039678
ENSMUST00000114964
NM_001047604
NM_011909
A_55_P2120706
NM_001009550
NM_001003893
NM_007840
NM_007912
NM_133649
NM_010008
NM_028173
XM_001475952
NM_027835
NM_172893
NM_001081150
NM_025804
NM_016773
NM_026949
NM_025590
NM_144915
XM_001474432
NM_021450
NM_001081349
NM_023143
ENSMUST00000029836
NM_009984
NM_008860
NM_183249
NM_007968
NM_001109985
NM_008377
NM_010573
NM_009780
NM_001004066
NM_133871
XM_001473119
NM_007956
NM_030721
NM_028937
logFC
-0,38
-0,30
-1,19
-0,32
-0,40
-0,27
-0,20
-0,22
-0,36
-0,34
-0,23
-0,45
-0,16
-0,36
-0,28
-0,33
-0,47
-0,20
-0,34
-0,22
-0,51
-0,28
-0,23
-0,29
-0,18
-0,19
-0,20
-0,30
-0,20
-0,44
-0,27
-0,43
-0,27
-0,26
-0,27
-0,26
-0,24
-0,14
-0,24
-0,27
-0,23
-0,23
-0,21
-0,26
-0,66
-0,28
-0,20
-0,35
tstat
-3,35
-3,35
-3,35
-3,35
-3,35
-3,34
-3,34
-3,34
-3,32
-3,29
-3,29
-3,28
-3,27
-3,25
-3,25
-3,23
-3,22
-3,22
-3,19
-3,19
-3,18
-3,18
-3,17
-3,17
-3,17
-3,17
-3,16
-3,14
-3,14
-3,14
-3,13
-3,13
-3,13
-3,12
-3,12
-3,12
-3,12
-3,12
-3,10
-3,10
-3,09
-3,09
-3,09
-3,07
-3,07
-3,07
-3,06
-3,06
p-value
3,37E-03
3,38E-03
3,41E-03
3,41E-03
3,42E-03
3,42E-03
3,42E-03
3,47E-03
3,62E-03
3,84E-03
3,84E-03
3,95E-03
4,02E-03
4,21E-03
4,26E-03
4,42E-03
4,53E-03
4,56E-03
4,84E-03
4,89E-03
4,99E-03
4,99E-03
5,03E-03
5,04E-03
5,05E-03
5,11E-03
5,15E-03
5,37E-03
5,45E-03
5,46E-03
5,54E-03
5,54E-03
5,56E-03
5,61E-03
5,63E-03
5,64E-03
5,65E-03
5,69E-03
5,94E-03
5,95E-03
6,03E-03
6,11E-03
6,12E-03
6,27E-03
6,35E-03
6,39E-03
6,47E-03
6,49E-03
q-value
1,53E-01
1,53E-01
1,53E-01
1,53E-01
1,53E-01
1,53E-01
1,53E-01
1,54E-01
1,58E-01
1,63E-01
1,63E-01
1,66E-01
1,68E-01
1,71E-01
1,72E-01
1,76E-01
1,79E-01
1,80E-01
1,87E-01
1,87E-01
1,89E-01
1,89E-01
1,90E-01
1,90E-01
1,90E-01
1,91E-01
1,91E-01
1,96E-01
1,97E-01
1,97E-01
1,97E-01
1,97E-01
1,97E-01
1,98E-01
1,98E-01
1,98E-01
1,98E-01
1,99E-01
2,05E-01
2,05E-01
2,06E-01
2,09E-01
2,09E-01
2,12E-01
2,14E-01
2,14E-01
2,15E-01
2,15E-01
Sup data Table 1B (continued). List of genes identified as down-regulated in the liver of mice fed the LIN
diet (rich in ALA) compared to mice fed the PALM diet (rich in SFA)..
ProbeName
A_51_P215438
A_51_P336622
A_55_P2023783
A_51_P179504
A_52_P219266
A_51_P510418
A_55_P2009066
A_55_P2043157
A_55_P2408330
A_55_P2019964
A_55_P1974780
A_51_P204845
A_52_P297642
A_51_P483511
A_55_P2003638
A_51_P472879
A_55_P2170881
A_51_P342926
A_55_P1975120
A_51_P308844
A_55_P2088965
A_55_P1998942
A_55_P1998943
A_55_P2023114
A_55_P2064568
A_51_P186547
A_55_P2029842
A_52_P530280
A_55_P2278965
A_51_P155503
A_55_P2063505
A_51_P359570
A_55_P2398995
A_52_P527842
A_55_P1969072
A_51_P327751
A_55_P2011385
A_55_P2117243
A_55_P2046398
A_55_P2107775
A_55_P1953931
A_66_P112482
A_55_P2119957
A_55_P2111980
A_51_P105017
A_55_P1994550
A_51_P431316
A_55_P1967216
GeneName
SystematicName
Prodh
NM_011172
Dexi
NM_021428
Leng8
NM_172736
Ang3
NM_001123394
Frmd8
NM_026169
Aldh1b1
NM_028270
2010015L04Rik
NM_001166029
Cadps2
NM_153163
Prr8
NM_028234
Lancl1
NM_021295
Gm3306
XM_001476301
ENSMUST00000111451 ENSMUST00000111451
Pdia5
NM_028295
Dock8
NM_028785
Stxbp6
NM_144552
Masp1
ENSMUST00000023605
Arhgap26
NM_175164
Omd
NM_012050
ENSMUST00000099432 ENSMUST00000099432
Nrn1
NM_153529
Scarb1
NM_016741
Oas1a
NM_145211
Oas1a
NM_145211
Hsd3b2
NM_153193
Anks1
NM_181413
Pah
NM_008777
Hnrnpa1
NM_001039129
Nsa2
NM_021552
5430420F09Rik
AK017326
Klk1b8
NM_008457
Gm4235
XM_001479508
Ifit3
NM_010501
Lelp1
NM_027042
Reps1
NM_009048
Cbx3
NM_007624
Ifit1
NM_008331
LOC637082
XM_916287
Npm1
AK088923
Eif4a1
NM_144958
Apol9a
NM_173786
Fam193a
NM_001030306
Tmem184c
NM_145599
Mlxipl
NM_021455
Hsd3b5
NM_008295
Rad52
NM_011236
Shank1
NM_001034115
Ube2w
NM_025773
Adam10
NM_007399
logFC
-0,37
-0,21
-0,26
-0,33
-0,25
-0,71
-0,24
-0,20
-0,25
-0,20
-0,48
-0,20
-0,31
-0,22
-0,22
-0,24
-0,36
-0,36
-0,21
-0,41
-0,26
-0,24
-0,40
-0,40
-0,27
-0,23
-0,15
-0,24
-0,21
-0,30
-0,32
-0,29
-0,19
-0,12
-0,15
-0,26
-0,41
-0,20
-0,19
-0,37
-0,15
-0,28
-0,32
-0,65
-0,18
-0,16
-0,13
-0,21
tstat
-3,06
-3,05
-3,04
-3,03
-3,03
-3,02
-3,01
-3,01
-3,00
-2,99
-2,99
-2,99
-2,98
-2,97
-2,97
-2,97
-2,97
-2,96
-2,96
-2,96
-2,94
-2,94
-2,94
-2,93
-2,91
-2,90
-2,90
-2,89
-2,89
-2,89
-2,89
-2,89
-2,89
-2,88
-2,88
-2,88
-2,88
-2,86
-2,85
-2,85
-2,85
-2,85
-2,85
-2,85
-2,84
-2,84
-2,84
-2,83
p-value
6,51E-03
6,63E-03
6,79E-03
6,90E-03
6,91E-03
7,12E-03
7,18E-03
7,21E-03
7,45E-03
7,51E-03
7,53E-03
7,56E-03
7,74E-03
7,84E-03
7,86E-03
7,93E-03
7,97E-03
7,99E-03
8,02E-03
8,07E-03
8,41E-03
8,45E-03
8,48E-03
8,62E-03
8,93E-03
9,26E-03
9,31E-03
9,33E-03
9,34E-03
9,37E-03
9,46E-03
9,48E-03
9,48E-03
9,53E-03
9,55E-03
9,64E-03
9,67E-03
1,00E-02
1,02E-02
1,02E-02
1,02E-02
1,03E-02
1,03E-02
1,04E-02
1,04E-02
1,05E-02
1,06E-02
1,07E-02
q-value
2,15E-01
2,18E-01
2,21E-01
2,23E-01
2,23E-01
2,26E-01
2,27E-01
2,27E-01
2,31E-01
2,32E-01
2,32E-01
2,32E-01
2,35E-01
2,36E-01
2,36E-01
2,37E-01
2,37E-01
2,37E-01
2,37E-01
2,38E-01
2,44E-01
2,45E-01
2,45E-01
2,47E-01
2,52E-01
2,59E-01
2,59E-01
2,59E-01
2,59E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,60E-01
2,61E-01
2,61E-01
2,68E-01
2,70E-01
2,70E-01
2,70E-01
2,71E-01
2,71E-01
2,71E-01
2,72E-01
2,73E-01
2,74E-01
2,75E-01
Sup data Table 1B (continued). List of genes identified as down-regulated in the liver of mice fed the LIN
diet (rich in ALA) compared to mice fed the PALM diet (rich in SFA)..
ProbeName
A_52_P330395
A_51_P198694
A_55_P2004168
A_55_P2303310
A_55_P2104572
A_51_P192089
A_52_P10041
A_55_P1961466
A_55_P2003053
A_55_P1955078
A_55_P2021510
A_55_P2144746
A_55_P2127179
A_55_P2155654
A_55_P1996578
A_55_P2107070
A_51_P140347
A_55_P2327518
A_52_P344290
A_51_P129012
A_51_P388847
A_55_P2068248
A_55_P2179246
A_55_P2023537
A_55_P1963767
A_55_P1968085
GeneName
Farp1
Gckr
LOC100046325
C730036E19Rik
6330416G13Rik
2610028A01Rik
Akr1b3
Dct
Dct
Tmem149
LOC100045679
Apip
Gm379
Pvt1
Fgfr3
Cabyr
Slc4a9
1500032P08Rik
F2r
B2m
Stap2
Gm2488
LOC100044553
LOC100046290
Npr2
A_55_P1968085
SystematicName
NM_134082
NM_144909
XM_001476023
AK050309
NM_144905
NM_028228
NM_009658
NM_010024
NM_010024
NM_145580
XM_001474939
NM_019735
XM_142052
NR_003368
NM_008010
NM_027687
NM_172830
AK005351
NM_010169
NM_009735
NM_145934
XM_001473755
XM_001472564
XM_001476520
NM_173788
A_55_P1968085
logFC
-0,16
-0,23
-0,36
-0,32
-0,27
-0,47
-0,30
-0,96
-0,89
-0,30
-0,16
-0,19
-0,69
-0,21
-0,27
-0,72
-0,22
-0,29
-0,28
-0,18
-0,28
-0,36
-0,45
-0,26
-0,20
-0,50
tstat
-2,83
-2,82
-2,82
-2,82
-2,81
-2,81
-2,81
-2,81
-2,80
-2,80
-2,80
-2,79
-2,78
-2,78
-2,78
-2,77
-2,77
-2,76
-2,76
-2,76
-2,76
-2,76
-2,76
-2,75
-2,75
-2,75
p-value
1,08E-02
1,10E-02
1,11E-02
1,11E-02
1,11E-02
1,11E-02
1,12E-02
1,13E-02
1,16E-02
1,16E-02
1,16E-02
1,16E-02
1,18E-02
1,19E-02
1,20E-02
1,22E-02
1,23E-02
1,24E-02
1,25E-02
1,25E-02
1,25E-02
1,26E-02
1,26E-02
1,27E-02
1,28E-02
1,29E-02
q-value
2,76E-01
2,80E-01
2,80E-01
2,80E-01
2,80E-01
2,80E-01
2,81E-01
2,83E-01
2,85E-01
2,85E-01
2,85E-01
2,86E-01
2,89E-01
2,89E-01
2,90E-01
2,93E-01
2,93E-01
2,95E-01
2,96E-01
2,96E-01
2,96E-01
2,96E-01
2,96E-01
2,97E-01
2,98E-01
2,99E-01
All genes with q-value<0.3 are provided. Genes in grey have q-value<0.05 and were used for plotting
heatmap and for functional categories (GO and KEGG) enrichment tests. Differentially expressed genes
were identified using the limma package of Bioconductor (www.bioconductor.org).
ProbeName: Unique identifier for Agilent Probe; GeneName: Gene symbol; SystematicName: Sequence
accession number; logFC: log2 fold change for LIN group vs PALM group; tstat: limma moderated tstatistic for LIN group vs PALM group; p-value: corresponding raw p-value; q-value: corresponding q-value
(to be used for filtering results based on FDR threshold).
Sup data Table 2A. Enrichment of Gene Ontology (GO) Biological Processes (BP) and KEGG Pathway
among the genes udown-regulated in the liver of mice fed the LIN diet (rich in ALA) compared to mice fed
the PALM diet (rich in SFA).
GOBPID
GO:0044710
GO:0055114
GO:0032788
GO:0032789
GO:0006082
GO:0044238
GO:0042178
GO:0051186
GO:0048252
GO:0044282
GO:0006637
GO:0001676
GO:0000038
GO:0006720
GO:0006104
GO:0043651
GO:0006066
GO:0071466
GO:0019752
GO:0006635
GO:0034440
Pvalue OddsRatio ExpCount Count Size
Term
7,46E-09
5,3
7,3
25 1289 single-organism metabolic process
8,67E-08
5,2
4,6
19
660 oxidation-reduction process
3,59E-07
Inf
0,0
3
3 saturated monocarboxylic acid metabolic process
3,59E-07
Inf
0,0
3
3 unsaturated monocarboxylic acid metabolic process
4,01E-06
5,5
2,8
13
406 organic acid metabolic process
2,01E-05
3,4
9,6
23 1176 primary metabolic process
5,69E-05
53,7
0,1
3
11 xenobiotic catabolic process
1,25E-04
7,0
1,1
7
157 cofactor metabolic process
1,53E-04
282,8
0,0
2
3 lauric acid metabolic process
1,93E-04
6,5
1,2
7
167 small molecule catabolic process
2,47E-04
14,8
0,3
4
44 acyl-CoA metabolic process
3,50E-04
25,9
0,1
3
20 long-chain fatty acid metabolic process
4,35E-04
23,8
0,2
3
21 very long-chain fatty acid metabolic process
4,81E-04
12,3
0,4
4
51 isoprenoid metabolic process
5,04E-04
94,3
0,0
2
5 succinyl-CoA metabolic process
5,04E-04
94,3
0,0
2
5 linoleic acid metabolic process
8,20E-04
6,0
1,1
6
157 alcohol metabolic process
1,03E-03
17,1
0,2
3
28 cellular response to xenobiotic stimulus
1,06E-03
4,8
1,6
7
246 carboxylic acid metabolic process
3,37E-03
11,0
0,3
3
42 fatty acid beta-oxidation
8,74E-03
7,6
0,4
3
59 lipid oxidation
KEGGID
PATH:00830
PATH:00071
PATH:00980
PATH:00982
PATH:00140
PATH:01100
PATH:03320
PATH:01040
PATH:00280
PATH:00380
PATH:00480
PATH:00983
PATH:00590
PATH:00640
Pvalue OddsRatio ExpCount Count Size
Term
9,24E-09
19,8
0,7
9
49 Retinol metabolism
4,95E-08
20,3
0,6
8
42 Fatty acid metabolism
3,86E-07
15,0
0,7
8
54 Metabolism of xenobiotics by cytochrome P450
1,31E-06
12,5
0,8
8
63 Drug metabolism - cytochrome P450
6,34E-05
14,4
0,4
5
33 Steroid hormone biosynthesis
7,03E-05
3,1
12,1
25
903 Metabolic pathways
1,49E-04
8,8
0,8
6
62 PPAR signaling pathway
2,10E-04
16,7
0,3
4
23 Biosynthesis of unsaturated fatty acids
2,59E-04
10,3
0,6
5
44 Valine, leucine and isoleucine degradation
9,87E-04
10,6
0,5
4
34 Tryptophan metabolism
2,40E-03
8,1
0,6
4
43 Glutathione metabolism
2,84E-03
7,7
0,6
4
45 Drug metabolism - other enzymes
4,50E-03
6,7
0,7
4
51 Arachidonic acid metabolism
7,13E-03
8,6
0,4
3
30 Propanoate metabolism
The enrichment of GO Biological Processes and KEGG pathways was evaluated with a conditional
hypergeometric test as implemented in the GOstats R package (Falcon and Gentleman, 2007).
Categories/pathways with at least 2 genes and a p-value <0.01 and were considered significantly enriched.
GOBPID / KEGGID: GO Biological Process (GOBP) or KEGG pathway identifier; Pvalue: P-value of the
enrichment test; OddsRatio: Odds ratio for the category tested: ExpCount: Expected number of genes from
the category in the selected genes; Count: Observed number of genes from the category in the selected
genes; Size: Number of genes annotated with the category in the gene universe; Term: GO Term.
Sup data Table 2B. Enrichment of Gene Ontology (GO) Biological Processes (BP) and KEGG Pathway
among the genes udown-regulated in the liver of mice fed the LIN diet (rich in ALA) compared to mice fed
the PALM diet (rich in SFA).
GOBPID
GO:0006953
GO:0006958
GO:0001702
GO:0035272
GO:0007162
GO:0072376
GO:1901568
GO:0046824
GO:0006959
Pvalue OddsRatio ExpCount Count Size
Term
1,64E-03
38,6
0,1
2
23 acute-phase response
1,94E-03
35,2
0,1
2
25 complement activation, classical pathway
2,26E-03
32,4
0,1
2
27 gastrulation with mouth forming second
2,26E-03
32,4
0,1
2
27 exocrine system development
4,39E-03
22,6
0,1
2
39 negative regulation of cell adhesion
4,44E-03
22,5
0,1
2
38 protein activation cascade
5,66E-03
19,7
0,1
2
43 fatty acid derivative metabolic process
8,81E-03
15,5
0,1
2
54 positive regulation of nucleocytoplasmic transport
9,13E-03
15,2
0,1
2
55 humoral immune response
KEGGID
PATH:00590
PATH:04610
PATH:00591
PATH:05219
PATH:05150
PATH:05213
PATH:05218
Pvalue OddsRatio ExpCount Count Size
Term
1,73E-05
36,14
0,2
4
51 Arachidonic acid metabolism
1,04E-03
19,05
0,2
3
63 Complement and coagulation cascades
3,47E-03
27,96
0,1
2
27 Linoleic acid metabolism
5,16E-03
22,51
0,1
2
33 Bladder cancer
6,45E-03
19,92
0,1
2
37 Staphylococcus aureus infection
8,27E-03
17,40
0,1
2
42 Endometrial cancer
9,86E-03
15,81
0,2
2
46 Melanoma
The enrichment of GO Biological Processes and KEGG pathways was evaluated with a conditional
hypergeometric test as implemented in the GOstats R package (Falcon and Gentleman 2007).
Categories/pathways with at least 2 genes and a p-value <0.01 and were considered significantly enriched.
GOBPID / KEGGID: GO Biological Process (GOBP) or KEGG pathway identifier; Pvalue: P-value of the
enrichment test; OddsRatio: Odds ratio for the category tested: ExpCount: Expected number of genes from
the category in the selected genes; Count: Observed number of genes from the category in the selected
genes; Size: Number of genes annotated with the category in the gene universe; Term: GO Term.