Introductory Biology Welcome to Introductory Biology Bio 160 1024.4 Lecture: M,W,F Room104 (2-3) Lab: T – Th Room 306 (2-4) Anna Davis, Ph.D., RYT What is Biology? bios = life (Greek) What fundamental characteristics are used to distinguish whether something is living or non-living? ology = branch of science, knowledge Unifying themes 1. Levels of organization are used to understand biology a. Structure and function are correlated at all levels of biological organization b. At each level, new properties emerge 2. Cells are the basic building blocks of all organisms 3. The continuity of life is based on the transfer of heritable information in the form of DNA from one generation to the next 4. Living organisms are different (diverse) and similar (unity) 5. Evolution accounts for the diversity and unity of life 6. Organisms are interdependent with their environments exchanging matter and energy Levels of Organization Ecosystem Community Population Organism Organ System Organ Tissue Cell Molecule Atom Levels of Organization: Novel properties emerge at each level Ecosystem: all the living and non-living components of particular area. living organisms: people, trees, moss, fish, grass, bacteria, fungus, etc. non-living: soil, sunlight, wind, rain, water, etc. Community: all the living components of a particular area; all the different species Population: interacting group of individuals of the same species Organism: an individual living thing Organ Systems: group of organs that function together to perform a vital bodily function Organ: a structure consisting of several tissues adapted as a group to perform a specific function Tissue: a cooperative unit of many similar cells that perform a specific function (within a multicellular organism) Cell: the fundamental structural unit of Life; a basic unit of living matter separated from its environment by a plasma membrane Molecule: two or more atoms held together by covalent bonds Atom: the smallest unit of matter that retains the properties of an element The biosphere Cells 10 µm Organs and organ systems Cell Ecosystems Organelles Communities 1 µm Atoms Tissues 50 µm Molecules Populations Organisms Levels of Organization: Structure and function are correlated Novel properties emerge at each level of organization: Cells Cells are the building blocks of life: There are two types of cells Membrane DNA (no nucleus) Membrane Cytoplasm Cytoplasm Organelles Nucleus (contains DNA) 1 µm 8 The continuity of life is based on the transfer of DNA from one generation to the next DNA = deoxyribonucleic acid. Sperm cell Nuclei containing DNA Egg cell Fertilized egg with DNA from both parents Embryo’s cells with copies of inherited DNA Living organisms are different (diverse) and similar (unity) Images not to scale SIMILAR Species: EX: Homo sapiens DIVERSE • Approximately 1.8 million species have been identified and thousands more are identified each year • The total number of species that actually exist on earth range are likely to be much larger (10 - 100 million) • Scientists organize the diversity of life into 3 large groups based on similarities and differences, These groups are called DOMAINS 1. 2. 3. Bacteria Archaea Eukarya 1. Planta 2. Fungi 3. Animalia Living organisms are different (diverse) and similar (unity) SIMILAR • The instructions used to build and maintain life are contained in DNA. These instructions are similar in all living organisms. Examples: Cilia of windpipe cells Cilia of Paramecium • Unity is evident in many features of cell structure (anatomy) and function (physiology) References • http://www.ornl.gov/sci/techresources/Human_Genome/education/ed ucation.shtml • http://www.genomenewsnetwork.org/resources/sequenced_genome s/genome_guide_p1.shtml • http://www.sciencemag.org/content/291/5507/1219.full • http://evolution.berkeley.edu/evolibrary/article/history_26 Cross section of a cilium, as viewed with an electron microscope Scientific Method 1. Observe some aspect of nature 2. Frame a question about your observation 3. Propose a hypothesis (a testable explanation of the observation) 4. Make a prediction – a statement based on a hypothesis, about some condition that should exist if the hypothesis is not wrong 5. Test the accuracy of the prediction by experiments or gathering information (tests may be performed on a model) 6. Assess the results of the tests (data) to see if they support or disprove the hypothesis 7. Conclusions: Report all steps of your work and conclusions to the scientific community Darwin’s Theory of Evolution accounts for the diversity and unity of life Species show evidence of “descent with modification” from common ancestors. Observations: 1. Individuals in a population have traits that vary, some traits are advantageous 2. Many of these traits are heritable (passed from parents to offspring in DNA) 3. More offspring are produced than survive because resources are limited 4. Competition for limited resources is inevitable 5. Species generally suit their environment (are well adapted) Darwin inferred that: – Individuals that are best suited to their environment are more likely to survive and reproduce – Over time, more individuals in a population will have the advantageous traits In other words, the natural environment “selects” for beneficial traits. Natural selection is the mechanism behind “descent with modification”. Natural selection does not create variation but screens for variations. Watch video: http://www.pbs.org/wgbh/nova/evolution/evolution-action-salamanders.html Berkely: http://evolution.berkeley.edu/evolibrary/article/evo_02 History of Life http://evolution.berkeley.edu/evolibrary/article/0_0_0/evo_13 Geologic time: http://evolution.berkeley.edu/evolibrary/search/lessonsummary.php?audience_level%5B2%5D=68&topic_id=&keywords=&type_id=&sort_by=audience_rank&Submit=Search&thisaudience=6-8&resource_id=26 Origin of solar system and Earth 4 1 Proterozoic 2 Archaean 3 16 Tree of Life: How are living organisms related to each other? Organisms are interdependent with their environments (ecosystem) Organisms are interdependent with their environments exchanging matter and energy Energy flows through ecosystems Nutrients cycle among organisms to sustain life. DEFINITONS – – – – Energy • The capacity to do work • Example: heat, light, chemical, kinetic, thermal Nutrient • Substance that is necessary for survival, but that an organism can’t make for itself • Example: minerals like iodine Producers • Organisms that make their own food using energy and simple raw materials from the environment • Example: plants Consumers • Organisms that get energy and carbon by feeding on tissues, wastes, or remains of other organisms • Example: animals, bacteria Details Instructor Office Hours Office Location Phone E-mail (preferred) Web Sites Lecture: MWF Lab: T Th Anna Davis, Ph.D., RYT MWF 1:30-2 PM and by appointment SAM 415 The best way to reach me is via email [email protected] http://www.seattlecentral.edu/faculty/adavis/ ANGEL: http://angel.seattlecentral.edu SAM 104; 2-2:50 PM SAM 305; 2 – 3:50 PM Biology Today and Tomorrow without Physiology, 3rd or 4th editions Starr/Evers/Starr. Used textbooks are fine too. Please note ISBN below includes CourseMate and e-book access which is optional. 4th edition: ISBN - 10 1133365361 ISBN-13: 9781133365365 3rd edition: ISBN-10: 0-495-95949-9, ISBN-13: 978-0-495-95949-6 © 2010 Textbook General Course Goals Learn Actively: • Ask “How do we know this?” and “Why does it matter?” • Think Critically and Reflect • Interpret, Present and Apply Your Knowledge SPECIFIC LEARNING OBJECTIVES •Identify the major themes of biology and list characteristics of living things. •Identify and distinguish the major characteristics of the domains and kingdoms of life •Demonstrate the methodology of scientific inquiry by observation, experimentation, data collection and data interpretation in problem solving and the generation of new knowledge. •Recognize that science is the study of the natural (physical) world and that science is based on common laws or principles and methods. •Describe the properties of carbon that make it the central component of organic compounds. •Compare the functions and chemical functional groups of the major groups of organic compounds: carbohydrates, lipids, proteins, and nucleic acids. •Demonstrate the special properties of water that support life. •Explain why the cell is the basic unit of life. •Compare and contrast properties of eukaryotic and prokaryotic cells. •Describe the structure and function of eukaryotic cell organelles. •Describe the fluid mosaic model of cell membrane structure in relationship to membrane function. •Describe how the first and second laws of thermodynamics relate to living systems. •Explain the chemical structure of ATP and its central role in metabolism. •Describe the relationship between enzyme properties and types and rates of chemical reactions. •Describe the processes of photosynthesis and how it is essential to all life •Describe aerobic cellular respiration and fermentation. •Describe the cell cycle and the process of mitosis. •Describe the process of meiosis. •Relate the contributions of Mendel to inheritance and solve inheritance problems using Mendel’s principles. •Describe the chemical and physical features of DNA and the major scientific discoveries that led to this understanding. •Discuss the significance of chromosomes in inheritance and the transmission of genetic information from generation to generation. •Outline the flow of genetic information in cells, from DNA to RNA to protein and how this process may be controlled. •Explain the scientific origins of biotechnological developments and evaluate the implications of those developments. •Summarize evidence supporting the theory of evolution. •Explain why evolution is the central theme of all biology. •Explain how genetic variation and selection are the basis for evolution in a given environment. •Use various laboratory techniques and equipment to observe specimens and perform experiments. •Develop the general skills (e.g., observation, problem solving, hypothesis generation and testing) used in science . Evaluations Assessment Method Point Value % Points 3 Exams 100 pts 37.5% 300 1 Cumulative Final Exam 200 pts 25% 200 4 Quizzes 30 pts 15% 120 8 - 12 Graded Homework Assignments (e.g. study questions, presentations, labs, etc. details will be provided) 10 - 30 pts 15% 120 Participation 60 pts 7.5% 60 TOTAL = 800 Test Reflections: As part of this course you will be required to submit corrected responses to any missed exam/quiz questions and a brief reflection on why you missed the question (rubric will be provided). These are due in writing 2 days after assessments are returned to you. You may earn “recapture” points on the first 2 quiz reflections and for Exam 1, and 1 additional quiz. To recapture points, you must defend your corrected test answers in-person with Dr. Davis It is highly encouraged that you recapture points. Up to 1/3 of missed points can be recaptured.
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