Online Resource 4. Summary of pooled skin surface pH and TEWL estimates
Article title:
Skin barrier function in infancy: a systematic review
Journal:
Archives of Dermatological Research
Authors:
Laine Ludriksone*, Natalie Garcia Bartels*, Varvara Kanti,
Ulrike Blume-Peytavi, Jan Kottner
* Both authors contributed equally to this paper.
Corresponding author:
Priv.-Doz. Dr. med. Natalie Garcia Bartels, M.D.
Charité-Universitätsmedizin Berlin
Department of Dermatology and Allergy
Clinical Research Center for Hair and Skin Science
Email: [email protected]
1
Online Resource 4. Summary of pooled skin surface pH and TEWL estimates
Summary of pooled skin surface pH estimates according to the random effects model and according to the sample size (n) for different skin areas
Age,
weeks
Volar forearm
Random effects
[95% CI]
Weighted
according to n
Abdomen
Random effects
[95% CI]
Weighted
according to n
0.0
Back
Random effects
[95% CI]
Weighted
according to n
6.02 [4.76-7.28]
(n = 101)
6.11
(n = 101)
5.24 [4.53-5.96]
(n = 60)
5.27
(n = 60)
Buttock
Upper leg
Random effects
[95% CI]
Weighted
according to n
Random effects
[95% CI]
Weighted
according to n
5.95 [5.85-6.05]
(n = 254)
5.95
(n = 254)
6.69 [6.50-6.87]
(n = 100)
6.72
(n = 100)
0.1
6.79 [6.67-6.91]
(n = 100)
6.78
(n = 100)
6.70 [6.54-6.86]
(n = 131)
6.71
(n = 131)
4.0
5.05 [4.93-5.17]
(n = 51)
5.05
(n = 51)
5.13 [4.92-5.34]
(n = 82)
5.17
(n = 182)
5.12 [5.02-5.23]
(n = 51)
5.15
(n = 151)
8.0
5.14 [5.04-5.23]
(n = 51)
5.14
(n = 51)
5.17 [4.96-5.38]
(n = 51)
5.22
(n = 67)
5.08 [4.98-5.18]
(n = 51)
5.13
(n = 67)
2
Online Resource 4. Summary of pooled skin surface pH and TEWL estimates
Summary of pooled TEWL estimates in g/m2/h according to the random effects model and according to the sample size (n) for different skin areas
Age,
weeks
Forehead
Random effects
[95% CI]
Weighted
according to n
Cheek
Random effects
[95% CI]
Weighted
according to n
Volar forearm
Random effects
[95% CI]
Weighted
according to n
Abdomen
Random effects
[95% CI]
Back
Weighted
according to n
0.0
0.1
12.1 [11.5-12.7]
(n = 109)
12.0
(n = 109)
9.1 [7.6-10.7]
(n = 177)
10.1
(n = 177)
0.3
4.4 [3.1-5.8]
(n = 57)
6.9
(n = 1106)
7.9 [2.4-13.4]
(n = 81)
8.4
(n = 242)
4.0
12.1 [11.4-12.8]
(n = 51)
12.1
(n = 51)
10.1 [9.5-10.8]
(n = 51)
8.0
11.1 [10.5-11.8]
(n = 51)
11.1
(n = 51)
11.9 [11.0-12.8]
(n = 51)
6.3 [3.1-9.6]
(n = 20)
7.6
(n =20)
7.2 [6.2-8.3]
(n = 38)
7.4
(n = 38)
5.8 [4.6-7.1]
(n = 20)
0.7
10.5
12.1 [10.0-14.2]
(n = 16)
12.6
(n = 16)
11.2
10.5 [8.7-12.4]
(n = 240)
10.5
(n = 240)
13.0
10.7 [8.7-12.6]
(n = 240)
10.7
(n = 330)
26.1
21.1 [17.7-24.5]
(n = 20)
Random effects
[95% CI]
Weighted
according to n
6.1 [3.9-8.4]
(n = 101)
7.4
(n = 101)
3.5 [3.1-4.0]
(n = 306)
3.6
(n = 306)
Buttock
Random effects
[95% CI]
Weighted
according to n
12.5 [11.6-13.5]
(n = 263)
12.6
(n = 263)
Lateral upper leg
Random effects
[95% CI]
Weighted
according to n
Upper leg (no specification)
Random effects Weighted
according to n
[95% CI]
11.3 [10.8-11.7]
(n = 100)
11.5
(n = 100)
9.2
(n = 151)
12.2 [11.7-12.7]
(n = 51)
9.5
(n = 151)
10.8
(n = 67)
11.9 [11.3-12.6]
(n = 51)
10.7
(n = 67)
6.0
(n = 20)
20.3
(n = 20)
40.3 [34.1-46.6]
(n = 35)
58.7
3
43.1
(n = 35)