Online Appendix 3. Summary of pooled skin surface pH and TEWL estimates
Article title:
Skin barrier function in infancy: a systematic review
Journal:
Archives of Dermatological Research
Authors:
Laine Ludriksone*, Natalie Garcia Bartels*, Varvara Kanti,
Ulrike Blume-Peytavi, Jan Kottner
* Both authors contributed equally to this paper.
Corresponding author:
Priv.-Doz. Dr. med. Natalie Garcia Bartels, M.D.
Charité-Universitätsmedizin Berlin
Department of Dermatology and Allergy
Clinical Research Center for Hair and Skin Science
Email: [email protected]
1
Online Appendix 3. Summary of pooled skin surface pH and TEWL estimates
Table 1. Summary of pooled skin surface pH estimates according to sample size
Anatomical measurement area
Age,
weeks
Forehead
0.0
6.90
(n = 41)
Cheek
Volar
forearm
Forearm
Hand
dorsum
7.31
(n = 41)
Palm
Chest
7.20
(n = 41)
6.78
(n = 100)
0.1
0.2
6.61
(n = 41)
0.3
5.79
(n = 120)
0.4
5.7
(n = 180)
6.80
(n = 41)
6.71
(n = 41)
Abdomen
Back
Inguinal
7.10
(n = 41)
6.11
(n = 101)
7.01
(n = 41)
6.71
(n = 131)
5.27
(n = 60)
6.81
(n = 41)
6.71
(n = 41)
Pelvis
Upper leg
6.70
(n = 31)
5.95
(n = 254)
6.72
(n = 100)
6.71
(n = 41)
6.90
(n = 41)
6.18
(n = 160)
6.10
(n = 180)
6.08
(n = 160)
5.80
(n = 180)
0.6
5.80
(n = 31)
5.60
(n = 31)
6.00
(n = 18)
0.7
1.0
5.19
(n = 47)
5.71
(n = 78)
5.60
(n = 31)
5.85
(n = 47)
5.60
(n = 47)
2.0
5.40
(n = 16)
5.38
(n = 87)
6.00
(n = 31)
5.67
( n = 36)
5.28
(n = 56)
5.89
(n = 6)
2.4
5.77
(n = 6)
6.05
(n = 6)
3.0
4.0
5.08
(n = 60)
4.3
4.93
(n = 163)
5.3
8.0
5.16
(n = 16)
12.9
4.79
(n = 179)
5.05
(n = 51)
5.48
(n = 163)
4.81
(n = 163)
5.61
(n = 3)
5.10
(n = 18)
5.90
(n = 31)
5.17
(n = 182)
5.90
(n = 31)
5.58
(n = 202)
5.15
(n = 151)
5.65
(n = 3)
5.22
(n = 67)
5.29
(n = 16)
4.83
(n = 179)
5.13
(n = 67)
5.56
(n = 179)
5.30
(n = 4)
19.3
5.10
(n = 31)
5.71
(n = 3)
5.14
(n = 51)
5.53
(n = 179)
6.06
(n = 6)
5.66
(n = 163)
5.48
(n = 3)
5.42
(n = 4)
5.55
(n = 4)
6.03
(n = 4)
19.6
4.79
(n = 44)
5.23
(n = 44)
5.45
(n = 44)
5.25
(n 44)
25.6
4.63
(n = 24)
4.94
(n = 24)
4.86
(n = 24)
4.73
(n = 24)
5.10
(n = 18)
26.1
5.20
(n = 302)
34.8
35.7
5.52
(n = 3)
5.48
(n = 3)
5.50
(n = 3)
5.68
(n = 20)
39.1
5.52
(n = 3)
5.59
(n = 20)
5.92
(n = 20)
5.06
(n = 35)
58.7
62.1
5.45
(n = 70)
62.6
4.90
(n = 18)
5.94
(n = 70)
2
Foot arch
7.00
(n = 41)
6.11
(n = 160)
5.69
(n = 180)
Buttock
Online Appendix 3. Summary of pooled skin surface pH and TEWL estimates
Table 2. Summary of pooled TEWL estimates according to sample size
Anatomical measurement area
Age,
weeks
Forehead
Cheek
Flexor
upper arm
Extensor
upper arm
Upper arm
(no specification)
Volar
forearm
0.0
10.1
(n = 41)
0.1
18.5
(n = 9)
0.2
9.9
(n = 41)
24.3
(n = 41)
0.3
9.2
(n = 121)
6.9
(n = 1106)
0.4
6.7
(n = 36)
Extensor
forearm
Forearm
Hand
dorsum
42.1
(n = 41)
12.7
(n = 9)
5.9
(n = 36)
12.9
(n = 9)
8.1
(n = 36)
8.0
(n = 9)
12.0
(n = 109)
5.1
(n = 36)
6.4
(n = 36)
Palm
Chest
31.0
(n = 41)
7.0
(n = 9)
6.5
(n = 9)
19.2
(n = 9)
5.2
(n = 9)
23.9
(n = 41)
Abdomen
Back
Inguinal
11.0
(n = 41)
7.4
(n = 101)
22.1
(n = 41)
10.1
(n = 177)
3.6
(n = 306)
9.8
(n = 41)
10.2
(n = 41)
Suprapubis
7.3
(n = 82)
26.5
(n = 36)
6.0
(n = 36)
5.7
(n = 36)
Medial
upper leg
Lateral
upper leg
Anterior
upper leg
Posterior
upper leg
Upper leg
(no specification)
6.0
(n = 20)
0.7
12.6
(n = 263)
7.1
(n = 9)
5.7
(n = 9)
11.5
(n = 100)
8.4
(n = 174)
Foot
dorsum
5.0
(n = 9)
7.7
(n = 9)
10.7
(n = 9)
4.6
(n = 9)
5.8
(n = 36)
7.8
(n = 160)
5.4
(n = 36)
6.9
(n = 36)
4.9
(n = 36)
5.2
(n = 36)
4.6
(n = 36)
11.0
(n = 36)
6.8
(n = 82)
9.6
(n =32)
4.6
(n = 32)
7.2
(n = 23)
1.0
9.7
(n = 48)
7.3
(n = 67)
9.5
(n = 48)
6.7
(n = 48)
2.0
8.1
(n = 16)
8.8
(n = 56)
9.5
(n = 36)
9.1
(n = 56)
4.0
9.5
(n = 60)
9.2
(n = 151)
15.4
(n = 204)
9.5
(n = 151)
8.2
(n = 32)
5.6
(n = 32)
5.2
(n = 32)
10.8
(n = 67)
8.2
(n = 16)
10.7
(n = 67)
11.5
(n = 44)
8.9
(n = 44)
12.1
(n = 51)
12.6
(n = 20)
4.4
14.6
(n = 32)
4.8
(n = 32)
4.9
(n = 32)
5.4
(n = 32)
5.6
(n = 20)
6.4
(n = 18)
5.3
8.0
7.8
(n = 16)
10.5
12.6
(n = 16)
11.2
10.5
(n = 240)
13.0
10.7
(n = 330)
11.1
(n = 51)
20.3
(n = 20)
7.6
(n =20)
3.9
(n = 25)
15.0
12.8
(n = 52)
19.1
13.0
(n = 44)
26.1
(n = 19)
25.5
(n = 19)
9.9
(n = 44)
22.7
(n = 586)
24.0
10.3
(n = 24)
8.9
(n = 24)
14.3
(n = 20)
24.3
(n = 611)
8.6
(n = 24)
6.8
(n = 24)
7.4
(n = 38)
11.1
(n = 30)
30.4
41.3
Foot arch
13.6
(n = 41)
6.2
(n = 32)
26.1
Lower leg
(no specification)
22.1
(n = 41)
0.8
25.6
Posterior
lower leg
3.1
(n = 10)
0.6
19.6
Anterior
lower leg
17.1
(n = 41)
8.4
(n = 242)
5.1
(n = 36)
Buttock
29.8
(n = 31)
16.9
(n = 31)
43.1
(n = 35)
58.7
62.1
8.3
(n = 70)
62.6
9.7
(n = 18)
9.1
(n = 70)
3
4.9
(n = 32)