Development 143: doi:10.1242/dev.128900: Supplementary information Development • Supplementary information Fig. S1. Comparison of ctsba exon reads in wild-type and split top mutant embryos using the Integrated Genomic Viewer. In split top mutant embryos ctsba transcript reads are greatly reduced relative to wild-type. In split top mutant embryos, exons 1, 6, 7 are not covered by any transcripts while exons 2-5, 8-10 have minimal coverage (≤4 transcripts per exon). Only a subset of the wild-type ctsba reads are shown. Development 143: doi:10.1242/dev.128900: Supplementary information Development • Supplementary information Movie 1. Time-lapse imaging of wild-type zebrafish embryo. Wild-type embryo development from blastula to somitogenesis stages. Development 143: doi:10.1242/dev.128900: Supplementary information Development • Supplementary information Movie 2. Time-lapse imaging of split top mutant embryo phenotypes. split top mutant embryo highlighting the developmental delay, separation of the EVL and the deep cells, and the lysis phenotype. Development 143: doi:10.1242/dev.128900: Supplementary information Development • Supplementary information Movie 3. Time-lapse imaging of split top mutant split-yolk phenotype. split top mutant embryo highlighting the development of the split-yolk phenotype. Development 143: doi:10.1242/dev.128900: Supplementary information Development • Supplementary information Movie 4. Time-lapse imaging of split top mutant early lysis phenotype. split top mutant embryo highlighting the development of the early lysis phenotype.
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