Applied Microbiology and Biotechnology
This file contains online supplemental material of the article by Kabelitz et al. 2007. EM.
Table S1.16S rRNA gene sequences obtained from HRB soil DNA amplifications
From HRB1:
>296-1-HRB1
Fo
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGGATAACGTAGGG
rP
AAACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGC
GCGGTTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGA
ee
CGATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATG
rR
CCGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCAT
TGGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCC
ev
AGCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTG
CGTAGGCGGTTGGTTAAGTCTGTCGTGAAATCCCCGGGTTCAACCTGGGAATGGCGATGG
iew
AAACTGGCCAGCTGGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGC
GTAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACGCTGACGCTGA
AGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGA
TGCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGACGCTAACGCGTTAAGTTCG
CCGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAA
GCGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATG
TCGCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAAAACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGT
CCTTAGTTGCCA
>296-11-HRB1
Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACCTCGGGA
AACCGGGACTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGTTGGACGGACCGATGTGCGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCAGGAGCGAAATACCACG
GGTCAATACCCTGTGGGGCTGACGGTACCTGAGGAATAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGGGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGGGTGC
Fo
GTAGGCGGTACGTTAGGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGGTAGA
AACCGGCGCACTAGAGTATGGGAGAGGGTGGTGGAATTACAGGTGTAGCGGTGAGATGCG
rP
TAGATATCTGGAGGAACATCAGTGGCGAAGGCGGCCACCTGGCCCAATACTGACGCTGAG
ee
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GAATACTAGATGTTTGGTGCCTAGCGTACTGAGTGTCGTAGCTAACGCGATAAGTATTCC
rR
GCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGGCTTGACATGTC
ev
CGGAATTCTGCAGAGATGCGGAAGTGCCCTTCGGGGAATCGGAACACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGT
>296-12-HRB1
iew
CCTTAGTTGCCA
AGCGGCGGACGGCTGAGTAACGCGTGGGAACATGCCCCAAAGTGAGGAATAACTGCCCGA
AAGGGTAGCTAATGCCGCATATGGTCTTCGGATTAAAGGATTTATCCGCTTTGGGAGTGG
CCTGCGCACGATTAGATAGTTGGTGAGGTAAAGGCTCACCAAGTCAACGATCGTTAGCTG
GTCTGAGAGGATGATCAGCCAGACTGGAACTGAGACACGGTCCAGACTCCTACGGGAGGC
AGCAGTGAGGAATCTTCCACAATGGGCGAAAGCCTGATGGAGCAACGCCGCGTGCAGGAT
GAAGGCCTTCGGGTCGTAAACTGCTTTTATAAGTGAAGAGTATGACGGTAACTTATGAAT
AAGCACCGGCTAACTACGTGCCAGCAGCCGCGGTCATACGTAGGGTGCAAGCATTATCCG
GAGTGACTGGGCGTAAAGAGTTGCGTAGGTGGACAAGTAAGCGAATAGTGAAATCTGGGG
Applied Microbiology and Biotechnology
GCTCAACCTCACAGACTATTACTCGAACTGCTTGTCTCGAGAGTGGTAGAGGTAACTGGA
ATTTCTAGTGTAGGAGTGAAATCCGTAGATATTAGAAGGAACACCAATGGCGTAGGCAGG
TTACTGGACCATTTCTGACACTGAGGCACGAAAGCGTGGGGAGCGAACGGGATTAGATAC
CCCGGTAGTCCACGCCGTAAACGATGGATACTAGCTGTTGGAGGTATCGACCCCTCCAGT
AGCGAAGCTAACGCGTTAAGTATCCCGCCTGTGGAGTACGGTCGCAAGACTAAAACATAA
AGGAATTGACGGGGACCCCCACAAGCGGTGGATCATGTTCTTTAATTCGATGATAAACGA
TAAACCTTACCAGGGCTTGACATCCCGAGAATTAATCCGAAAGGATTGAGTGCTTTTAGA
ACTCGGTGACAGATCTTGCATGGCCGTCGTCAGCTCGTGTTGTGAGATGTTTGGTTAAGT
Fo
CCATCAACGAGCGCAACCCTTGTGAATAGTTGTAT
>296-18-HRB1
rP
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
ee
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
rR
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGGCAATGGGCGCAAGCCTGATCCAGCAATGC
ev
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
iew
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAGGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAATTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAACACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
Applied Microbiology and Biotechnology
CTTAGTTGCCA
>296-23-HRB1
AGTGGCGGACGGGTGAGTAATGCGTAGGAATCTGTCTTTTAGTGGGGGACAACCCAGGGA
AACTTGGGCTAATACCGCATGAGCCCTGAGGGGGAAAGCGGGGGATCTTCGGACCTCGCG
CTAAGAGAGGAGCCTACGTCCGATTAGCTAGTTGGCGGGGTAAAGGCCCACCAAGGCGAC
GATCGGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTTCGCAATGGGGGCAACCCTGACGAAGCAATGC
CGCGTGGATGAAGAAGGCCTTCGGGTTGTAAAGTCCTTTCGTGGAGGACGAAAAGGTGGG
Fo
TTCTAATACAATCTGCTATTGACGTGAATCCAAGAAGAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGGGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGGGTGC
rP
GTAGGCGGTACGTTAGGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGGTAGA
ee
AACCGGCGCACTAGAGTATGGGAGAGGGTGGTGGAATTCCAGGTGTAGCGGTGAAATGCG
TAGATATCTGGAGGAACATCAGTGGCGAAGGCGGCCACCTGGCCCAATACTGACGCTGAG
rR
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GAATACTAGATGTTTGGTGCCTAGCGTACTGAGTGTCGTAGCTAACGCGATAAGTATTCC
ev
GCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGGCTTGACATGTC
iew
CGGAATTCTGCAGAGATGCGGAAGTGCCCTTCGGGGAATCGGAACACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTAT
CCTTAGTTGCCA
>296-24-HRB1
AGTGGCGAACGGGTGAGTAATACATCGGAACGTGCCCGATCGTGGGGGACAACGAAGCGA
AAGCTTTGCTAATACCGCATACGATCCACGGATGAAAGCAGGGGACCGCAAGGCCTTGCG
CGAACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGTCTG
Applied Microbiology and Biotechnology
CCCTAATACGGTGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTGATGTAAGACAAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATATGT
GACTGCATCGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAATTGGTTGTTGGGGATTCACTTCCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
Fo
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAAGATTGCAGAGATGCGATTGTGCTCGAAAGAGAGCCGTAACACAGGTGCTGCATGGC
rP
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGCC
>296-25-HRB1
ee
ATTAGTTGCTA
rR
AGCGGCAGACGGGTGAGTAACGCGTGGGAACGTACCTTTTGGTTCGGAACAACACAGGGA
AACTTGTGCTAATACCGGATAAGCCCTTACGGGGAAAGATTTATCGCCGAAAGATCGGCC
ev
CGCGTCTGATTAGTTAGTTGGTGAGGTAATGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
iew
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
AGGCCCTAGGGTTGTAAAGCTCTTTTGTGCGGGAAGATAATGACGGTACCGCAAGAATAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ATCACTGGGCGTAAAGGGTGCGTAGGCGGGTCTTTAAGTCAGGGGTGAAATCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGAGGATCTTGAGTTCGGGAGAGGTGAGTGGAACTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCCCGATACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTTAGTGGGTTTACTCACTAGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAACC
Applied Microbiology and Biotechnology
TTACCAGCCCTTGACATCCCGGTCGCGGATTCCAGAGACGGAATCCTTCAGTTCGGCTGG
ACCGGAGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTC
CCGCAACGAGCGCAACCCCCGTCCTTAGTTGCTA
>296-3-HRB1
AGTGGCGCACGGGTGAGTAACGCGTGGGAACCTGCCCTTTTGTTCGGAATAACGTTGGGT
AACTGACGCTAATACCGGATACGCCCTTCGGGGGAAAGATTTATCGCAGAAGGAGGGGCC
CGCGTCAGATTAGCTAGTTGGTGGGGTAATGGCCTACCAAGGCGATGATCTGTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
Fo
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
AGGCCTTAGGGTTGTAAAGCTCTTTCGCACGCGACGATGATGACGGTAGCGTGAGAAGAA
rP
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGA
ee
ATTACTGGGCGTAAAGGGCGCGTAGGCGGTTTATCAAGTCAGGCGTGAAAGCCCCGGGCT
CAACCTGGGAATTGCGTTTGATACTGGTAGACTTGAGTTCGGGAGAGGTGAGTGGAATTC
rR
CCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGTGGCGAAGGCGGCTCAC
TGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
ev
GTAGTCCACGCCGTAAACGATGTGCGCTAGACGCTGGGAAACTTAGTTTTCCGGTGTCGC
AGCTAACGCATTAAGCGCACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAAGGAA
iew
TTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAAC
CTTACCAACCCTTGACATGGGAAGTATGGTCCCCGGAGACGGGGTCCTTCAGTTCGGCTG
GCTTCCACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCCTATCTTTAGTTGCCA
>296-31-HRB1
CATGGCAGACGGGTGAGTAACGCGTAGGGAATCTACCTTTTTGTGGGGAATAACGCTCCG
AAAGGAGTGGTAATACCGCATGAGACCGTCGACTGGGATGTCGGTGGTGAAACCTGGGGA
CCGCAAGGCCTGGGGCAAAAAGAGGATCCTGCGTCTGATTAGCTAGTTGGCGGGGTAATG
GCCCACCAAGGCGACGATCAGTAGCCGGCCTGAGAGGGTGATCGGCCACACTGGAACTGA
GACACGGTCCAGACTCCTACGGGAGGCAGCAGTGGGGAATTTTGCGCAATGGACGAGAGT
Applied Microbiology and Biotechnology
CTGACGCAGCAACGCCGCGTGGGTGATGAAGGTCTTCGGACTGTAAAACCCTGTCGTCAG
GGACGAAGGCATGGGAGTTAATAGCTCTTATGCTTGACGGTACCTGGAGAGGAAGCCCCG
GCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGGGGCAAGCGTTATTCGGAATTATT
GGGCGTAAAGGGCGCGTAGGCGGTTTTTTAAGTCAGATGTGTAATCCCCGAGCTCAACTT
GGGAACTGCATCTGAGACTGGAAGGCTAGAGTACTGGAGAGGGTGGTGGAATTCCTCGTG
TAGCGGTGAAATGCGTAGAGATGAGGAGGAACACCAGTGGCGAAGGCGGCCACCTGGACA
GTAACTGACGCTGAGGCGCGAAAGTGTGGGTAGCAAACAGGATTAGATACCCTGGTAGTC
CACGCTGTAAACGATGAACACTTGGTGTGGAGGGAGTTGACCCCCTTCCGTGCCGGAGCT
Fo
AACGCGTTAAGTGTTCCGCCTGGGGAGTACGGTCGCAAGGCTGGAACTCAAAGGAATTGA
CGGGGGCCCGCACAAGCGGTGGAGCATTGGGTTTAATTCGACGCAACGCGAAGAACCTTA
rP
CCTGGGCTTGAACTGTGGTGGACCGGTGCAGAGATGTGCCTTTTCGCAAGAACTGCTACA
AGCGCAACCCTTACCCGTAGTTGCCA
rR
>296-33-HRB1
ee
GAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGATTAAGTCCCGCAACG
AGTGGCGGACGGGTGAGTAATGCGTAGGAATCTGTCTTTTAGTGGGGGACAACCCAGGGA
ev
AACTTGGGCTAATACCGCATGAGCCCTGAGGGGGAAAGCGGGGGATCTTCGGACCTCCCG
CTAAGAGAGGAGCCTACGTCCGATTAGCTAGTTGGCGGGGTAAAGGCCCACCAAGGCGAC
iew
GATCGGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTTCGCAATGGGGGCAACCCTGACGAAGCAATGC
CGCGTGGATGAAGAAGGCCTTCGGGTTGTAAAGTCCTTTCGTGGAGGACGAAAAGGTGGG
TTCTAATACAATCTGCTATTGACGTGAATCCAAGAAGAAGCACCGGCTAACTCCGTGCCA
GTAGCCGCGGTAATACGGGGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGGGTGC
GTAGGCGGTACGTTAGGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGGTAGA
AACCGGCGCACTAGAGTATGGGAGAGGGTGGTGGAATTCCAGGTGTAGCGGTGAAATGCG
TAGATATCTGGAGGAACATCAGTGGCGAAGGCGGCCACCTGGCCCAATACTGACGCTGAG
ACACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GAATACTAGATGTTTGGTGCCTAGCGTACTGAGTGTCGTAGCTAACGCGATAAGTATTCC
Applied Microbiology and Biotechnology
GCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGGCTTGACATGTC
CGGAATTCTGCAGAGATGCGGAAGTGCCCTTCGGGGAATCGGAACACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGT
CCTTAGTTGCCA
>296-34-HRB1
AGTGGCGAACGGGTGAGTAATATATCGGAACGTGCCCAGTCGTGGGGGATAACGTAGAGA
AATTTACGCTAATACCGCATACGATCTAAGGATGAAAGCGGGGGACCTTCGGGCCTCGCG
Fo
CGATTGGAGCGGCTGATATCAGATTAGGTTGTTGGTGAGGTAAAAGCTCACCAAGCCGAC
GATCTGTAGCTGGTTTGAGAGAACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
rP
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGAAAGCCTGATCCAGCAATGC
ee
CGCGTGCAGGAAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGTCTG
CCCTAATACGGCGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
rR
GCAGCCGCGGTAATACGTAGGGTGCGAGCGTTAATCGGAATTACTGGGCGGAAAGCGTGC
GCAGGCGGTTATGTAAGACAGTTGTGAAATCCCCGGGCTCAACCTGGGAATTGCATCTGT
ev
GACTGCATAGCTAGAGTACGGTAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGATCTGTACTGACGCTCAT
iew
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGTGCATTAGTACTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCTACCTTTGACATGTAC
GGAACTCGCCAGAGATGGCTTGGTGCTCGAAAGAGAACCGTAACACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
ATTAGTTGCTA
>296-37-HRB1
AGTGGCGCACGGGTGAGTAACGCGTGGGAATCTGCCCTGTGGTACGGAATAACATCGGGA
AACTGGTGCTAATACCGTATATCCCCTGAGGGGGAAAGATTTATCGCCATGGGAGGAGCC
Applied Microbiology and Biotechnology
CGCGTAGGATTAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGGGAAACCCTGATCCAGCCATGCCGCGTGTGTGATGA
AGGCCTTCGGGTTGTAAAGCACTTTCGCACGTGACGATGATGACGGTAACGTGAGAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCAAGCGTTGTTCGGA
ATTACTGGGCGTAAAGGGCGCGTAGGCGGTGCTCTAAGTCAGGCGTGAAAGCCCTGGGCT
CAACCCGGGAATTGCGCTTGATACTGGAGCGCTTGAATCCAGGAGGGGTTGGTGGAATTC
CCAGTGTAGAGGTGAAATTCGTAGAGATTGGGAAGAACACCGGTGGCGAAGGCGGCCAAC
Fo
TGGACTGGTATTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCTGTAAACGATGTGTGCTAGCCGTTGGGGCTCTTAGAGCTTCGGTGGCGT
rP
CGCTAACGCTTTAAGCACACCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAA
ee
TTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCTCTTGACATGGGGAGTTCGGATGCCAGAGATGGCAACCTTCAGTTCGGCTG
CCCGCAACGAGCGCAACCCTCATCGTCAGTTGCCA
ev
>296-4-HRB1
rR
GCTCCCACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
AGTGGCGAACGGGTGAGTAACACGTGAGCAATCTGCCCTGGACTCTGGGATAAGCGTTGG
iew
AAACGACGTTTAATACCGGATACGCGACGCGAAGGCATCTTCAGCGTCGGGAAAGAACTT
CGGTCCAGGATGAGCTCGCGGCCTATCAGCTAGTTGGTGAGGTAACGGCCCACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGTGACCGGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCAAC
GCCGCGTGAGGGACGACGGCCTTCGGGTTGTAAACCTCTTTTAGTAGGGAAGAAGCGAAA
GTGACGGTACCTGCAGAAAAAGCACCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGT
AGGGTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGTTTGTCGCGT
CTGCTGTGAAAACTGGAGGCTCAACCTCCAGCCTGCAGTGGGTACGGGCAAACTAGAGTG
CGGTAGGGGAGATTGGAATTCCTGGTGTAGCGGTGGAATGCGCAGATATCAGGAGGAACA
CCGATGGCGAAGGCAGATCTCTGGGCCGTAACTGACGCTGAGGAGCGAAAGCATGGGGAG
Page 45 of 160
CGAACAGGATTAGATACCCTGGTAGTCCATGCCGTAAACGTTGGGCGCTAGATGTGGGGA
CCATTCCACGGTTTCCGTGTCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGC
CGCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGCGGAT
TAATTCGATGCAACGCGAAGAACCTTACCAAGGCTTGACATATACCTGAAAAGGCTGGAA
ACAGTCTCCCCGCAAGGCAGGTATACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTG
AGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTTCTATGTTGCCA
>296-40-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAATAATAGTTAGA
Fo
AATGACTGCTAATACCGGATGATGACGAAAGTCCAAAGATTTATCGCCAAGGGATGAGCC
CGCGTAGGATTAGGTAGTTGGTGGGGTAAAGGCCTACCAAGCCGACGATCCTTAGCTGGT
rP
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
ee
AGGCCCTAGGGTCGTAAAGCTCTTTTACCAGGGACGATAATGACAGTACCTGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTGTTCGGA
rR
ATTACTGGGCGTAAAGCGTACGTAGGCGGTTATTCAAGTCAGAGGTGAAAGCCCGGGGCT
CAACCCCGGAACTGCCTTTGAAACTAGGTAACTAGAGTCTTGGAGAGGTTAGTGGAATTC
ev
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTAAC
iew
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
Applied Microbiology and Biotechnology
TGGACAAGTACTGACGCTGAGGTACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCCGGGCACTTGGTGTTTGGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGTCGCAAGATTTAAAACTCAAAGGA
ATTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAA
CCTTACCAGCGTTTGACATCCCGCGCTAACCCAAGAGATTGGGTGTTCCCTTCGGGGACG
CGGTGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCC
GCAACGAGCGCAACCCTCGTCCTTAGTTGCCA
>296-42-HRB1
AGTGGCGGACGGGTGAGTAATGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
Applied Microbiology and Biotechnology
CGGTTGGACGGACCGATGTGCGATTAGCTAGTTGGCGGGGTAATGGCCCCCCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATG
GGTTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTATTACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
Fo
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
rP
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
ee
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAACACAGGTGCTGCATGGC
rR
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
CTTAGTTGCCA
>296-45-HRB1
iew
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AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
ACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCGC
GGTTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGACG
ATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACTC
CTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGCC
GCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATTG
GCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCAG
CAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGCG
TAGGCGGTTGGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGAA
ACTGGCCAGCTGGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCGT
Page 46 of 160
Page 47 of 160
AGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAAG
CACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGATG
CGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGCC
GCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGTC
GCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAACACAGGTGCTGCATGGCT
GTCGTCAGTTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTCC
TTAGTTGCCA
>296-46-HRB1
Fo
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
rP
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
ee
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
rR
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTAGGTTGGGAAGAAAAAATTCG
GGCGAATATCCCGAGTCTTGACGGTACCGACAGAATAAGCACCGGCTAACTCTGTGCCAG
ev
CAGCCGCGGTAATACAGAGGGTGCTAGCGTTAATCGGATTTACTGGGCGTAAAGCGTGCG
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Applied Microbiology and Biotechnology
TAGGCGGTTTTGTTAAGTCGGTTGTGAAAGCCCCGGGCTCAACCTGGGAATTGCAGACGA
TACTGGCAGACTAGAGAACGGTAGAGGGAGGCGGAACTCCAGGTGTAGCGGTGAAATGCG
TAGATATCTGGAAGAACACCGATGGCGAAGGCAACCTCCTGGGCCTGTTCTGACGCTGAG
GCACGAAAGCGTGGGTAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GAGAACTTGACGTCCGGTTTGCTTAGCAAATCGGTGTCGTAGCTAACGCGATAAGTTCTC
CGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGTCTTGACATGT
CGAGAAGTCTGCAGAGATGCGGATGTGCCTTCGGGAACTCGAACACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGCC
CTTAGTTGCCA
Applied Microbiology and Biotechnology
>296-55-HRB1
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTCGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
Fo
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
rP
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGATGCTCAT
ee
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
rR
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTA
ev
CGGAATCCTTCAGAGATGAAGGAGTGCTCGAAAGAGAACCGTAACACAGGTGCTGCATGG
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CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGT
CATTAGTTGCTA
>296-56-HRB1
AGCGGCAGACGGGTGAGTAACGCGTGGGAACGTACCTTTTGGTTCGGAACAACACAGGGA
AACTTGTGCTAATACCGGATAAGCCCTTACGGGGAAAGATTTATCGCCGAAAGATCGGCC
CGCGTCTGATTAGCTAGTTGGTGAGGTAATGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
AGGCCCTAGGGTTGTAAAGCTCTTTTGTGCGGGAAGATAATGACGGTACCGCAAGAATAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
Page 48 of 160
Page 49 of 160
ATCACTGGGCGTAAAGGGTGCGTAGGCGGGTCTTTAAGTCAGGGGTGAAATCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGAAGATCTTGAGTTCGGGAGAGGTGAGTGGAACTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACGCCAGTGGCGAAGGCGGCTCAC
TGGCCCGATACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTTAGTGGGTTTACTCACTAGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAACC
TTACCAGCCCTTGACATCCCGGTCGCGGATTCCAGAGACGGAATCCTTCAGTTCGGCTGG
Fo
ACCGGAGACAGGTGCTGCATGGCTGTCTTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTC
CCGCAACGAGCGCAACCCCCGTCCTTAGTTGCTA
>296-57-HRB1
rP
AGTGGCGTACGGGTGAGTAACACGTGACTAACCTACCCTTGAGTGGGGGATAACCTCGGG
ee
AAACCGTGGCTAATACCGCATAACACCGAAAGGTCAAAGGAGCAATTCGCTTAAGGAGGG
GGTCGCGGCTGATTAGCTAGTTGGTTAGGGTAATGGCCTACCAAGGCGACGATCAGTAGC
rR
CGGCCTGAGAGGGCGCACGGCCACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAG
GCAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGG
ev
ATGAAGTCCCTTGGGATGTAAACTCCTTTCGATCGGGACGATAATGACGGTACCGGAAGA
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Applied Microbiology and Biotechnology
AGAAGCACCGGCTAACTCTGTGCCAGCGGCCGCGGTAATACAGAGGGTGCAAGCGTTGTT
CGGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTGCGGTAAGTCTTTTGTGAAATCTCCG
GGCTCAACTCGGAGCCTGCAGGAGAAACTGCCGTGCTGGAGTATGGGAGAGGTGAGTGGA
ATTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTGTGGCGAAAGCGGC
TCACTGGACCATTACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATAC
CCTGGTAGTCCTAGCCCTAAACGATGATTGCTTGGTGTGGCAGGTACCCAATCCTGCCGT
GCCGAAGCTAACGCGATAAGCAATCCGCCTGGGGAGTGCGGTCGCAAGGCTGAAACTCAA
AGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGACGCAACGCGA
AGAACCTTACCTGGGCTCGAAGCGCAGTGGACTGCGGTAGAAATATCGCTTTCTCGCAAG
AGACTGCTGCGTAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAA
Applied Microbiology and Biotechnology
GTCCCGCAACGAGCGCAACCCTTATTGCCAGTTGCCA
>296-60-HRB1
CATGGCAGACGGGTGAGTAACGCGTGGGGAACCTACCTCTTTGTGGGGAATAACGCTCCG
AAAGGAGTGGTAATACCGCATGAGACCTTCAGCTGGGATGCTGGAGGTGAAACCTGGGGA
CCAGCAATGGCCTGGGGCAAGGAGAGGGTCCTGCGTCTGATTAGCTAGTTGGCGGGGTAA
TGGCCCACCAAGGCATCGATCAGTAGCCGGCCTGAGAGGGTGATCGGCCACACTGGAACT
GAGACACGGTCCAGACTCCTACGGGAGGCAGCAGTGGGGAATTTTGCGCAATGGGCGAAA
GCCTGACGCAGCAACGCCGCGTGGGTGATGAAGGTCTTCGGATTGTAAAACCCTGTCGTC
Fo
AGGGACGAAGGTGCACATGTTAATAGCGTGTGTGCTTGACGGTACCTGGAGAGGAAGCCC
CGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGGGGCAAGCGTTATTCGGAATTA
rP
TTGGGCGTAAAGGGCGCGTAGGCGGTTTTTTAAGTCAGATGTGTAATCCCCGAGCTTAAC
TTGGGAACTGCATCTGAGACTGGAAGGCTAGAGTACTGGAGAGGGTGGTGGAATTCCTCG
ee
TGTAGCGGTGAAATGCGTAGAGATGAGGAGGAACACCAGTGGCGAAGGCGGCCACCTGGA
CAGTAACTGACGCTGAGGCGCGAAAGTGTGGGTAGCAAACAGGATTAGATACCCTGGTAG
rR
TCCACGCTGTAAACGATGAACACTTGGTGTGGAGGGAGTTGACCCCTTCCGTGCCGGAGC
TAACGCGTTAAGTGTTCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAAGGAATTG
ev
ACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAAGAACCTT
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ACCTGGGCTTGAACTGCAGTGGACCGGTGCAGAGATGTGCCTTTTCGCAAGAACTGCTGC
AGAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAAC
GAGCGCAACCCTTACCCGTAGTTGCCA
>296-65-HRB1
AGTGGCGAACGGGTGAGTAATACATCGGAACGTGCCCGATCGTGGGGGACAACGAAGCGA
AAGCTTTGCTAATACCGCATACGATCCACGGATGAAAGCAGGGGACCGCAAGGCCTTGCG
CGAACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGATTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGTCTG
Page 50 of 160
Page 51 of 160
CCCTAATACGGTGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTGATGTAAGACAAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATATGT
GACTGCATCGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGGATTCACTTCCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
Fo
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAAGATTGCAGAGATGCGATTGTGCTCGAAAGAGAGCCGTAACACAGGTGCTGCATGGC
rP
TGTCGTCAGCTCGTGTCGTGAGATGGTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGCC
ATTAGTTGCTA
>296-70-HRB1
ee
AGCGGCAGACGGGTGAGTAACGCGTGGGGATGTGCCCAGAGGTGGGGAATAACTGTGGGA
rR
AACTACAGCTAATACCGCATGAGCCCTTCGGGGGAAAGAGTTATCGCCTTTGGATCAACC
CGCGTCAGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGATCTGTAGCTGGT
ev
CTGAGAGGATGACCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
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Applied Microbiology and Biotechnology
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCTAGCCATGCCGCGTGAGTGATGA
CGGCCTTAGGGTTGTAAAGCTCTTTTAACAGGGACGATAATGACGGTACCTGTAGAATAA
GCCCCGGCAAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGA
ATTACTGGGCGTAAAGCGCACGTAGGCGGATTGTTAAGTCGGGGGTGAAATCCTGAGGCT
CAACCTCAGAACTGCCTTCGATACTGGCGATCTTGAGTTCGGAAGAGGTTGGTGGAACAG
CTAGTGTAGAGGTGAAATTCGTAGATATTAGCTAGAACACCAGTGGCGAAGGCGGCCAAC
TGGTCCGACACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTCGGGGAGCTTGCTCTTCGGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACC
Applied Microbiology and Biotechnology
TTACCTGGCCTTGACATGTCGCGAACCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCG
AACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGC
AACGAGCGCAACCCTTGTCCTTAGTTGCCA
>296-71-HRB1
AGTGGCGAACGGGTGAGTAATACATCGGAACGTACCCGATCGTGGGGGACAACGAAGCGA
AAGCTTTGCTAATACCGCATACGATCCACGGATGAAAGCAGGGGACCGCAAGGCCTTGCG
CGAACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
Fo
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGTCTG
rP
CCCTAATACGGTGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCATGC
ee
GCAGGCGGTGATGTAAGACAAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATATGT
GACTGCATCGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
rR
TAGATATGCGGAGGAACACCGATAGCGAGGGCAATCCCCTGGGCCTGCACTGGCGCTCAT
GCACGAAAGCGTGGGGAGCAAACACGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
ev
GTCAACTGGTTGTTGGGGATTCACTTCCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
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CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAAGATTGCAGAGATGCGATTGTGCTCGAAAGAGAGCCGTAACACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGCC
ATTAGTTGCTA
>296-72-HRB1
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTTGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
Page 52 of 160
Page 53 of 160
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGGTATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
Fo
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
rP
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGATGAAGGAGTGCTCGAAAGAGAACCGTAACACAGGTGCTGCATGGC
ee
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
ATTAGTTGCTA
>296-74-HRB1
rR
AGTGGCGGACGGGTGAGTAATGTATAGGAATCTGCCTTGTAGTGGGGGATAACTAGGGGA
ev
AACTCTGGCTAATACCGCATAACCTCTACGGAGTAAAGCGGGGGACCGTAAGGCCTCGCG
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Applied Microbiology and Biotechnology
CTATAAGATGAGCCTATATTGGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCAAC
GATCCATAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGAAACCCTGATCCAGCAATGC
CGTGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTAGTGGGAAAGAAAAGCTTGA
AACTAATAACTTCGAGCTGTGACGTTACCCACAGAAAAAGCACTGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGAGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCAC
GTAGGTGGATTTTTAAGTCAGATGTGAAAGCCCCGAGCTTAACTTGGGAATTGCATTTGA
TACTGGGAGTCTAGAATATAGTAGAGGGAGGTGGAATTTCCGGTGTAGCGGTGAAATGCG
TAGATATCGGAAGGAACATCAGTGGCGAAAGCGGCCTCCTGGACTAATATTGACACTTAG
GTGCGAAAGCGTGGGGAGCAAACAGGACTAGAGACCCTGGTAGTCCACGCCGTCAACGAT
Applied Microbiology and Biotechnology
GATAACTAGATGTTGGGGAGCTTGCTCCTTAGTATCGAAGCTAACGCGTTAAGTTATCCG
CCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCG
GTGGAGCATGCGGTTTAATTCGATGCAACGCGAAGAACCTTACCTACTTTTGACATCCTC
GGAATCTTCTAGAGATAGAAGAGTGCCTTCGGGAACCGAGAGACAGGTGCTGCATGGCTG
TCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTCGTCCT
TAGTTGCCA
>296-76-HRB1
AGTGGCGAACGGGTGAGTAAAGCATCGGAACGTGCCCGATCGTGGGGGATAACGCAGCGA
Fo
AAGCTGCGCTAATACCGCATAAGATCTACGGATGAAAGCGGGGGACTCGCAAGAGCCTCG
CGCGAACGGAGCGGCCGATGTCAGATTAGGTAGTTGGTGGGGTAAAGGCCCACCAAGCCG
rP
ACGATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCAT
ee
GCCGCGTGCAGGGAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAGCGAAAAGGCC
CCTACTAACACTGGGGGTCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGC
rR
CAGCAGCCGGGTAATACGTAGGGTCGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGT
GCGCAGGGCGGTTTTGTAAAGACAGAGGTGAAATCCCCGGGCTCAACCTGGGAACTGCCT
ev
TTGTGAACTGCAAAGGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGA
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AATGCGTAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGAC
GCTTATGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTA
AACGATGTCAACTGGTTGTTGGGTCTTAGCTGACTCAGTAACGAAGCTAACGCGTGAAGT
TGACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCA
CAAGCGGTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGAC
ATGTACGGAAGTTGCCAGAGATGGCTTCGTGCTCGAAAGAGAGCCGTAACACAGGTGCTG
CATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACC
CTTGCCATTAGTTGCTA
>296-8-HRB1
AGCGGCAGACGGGTGAGTAACGCGTGGGGATGTGCCCAGAGGTGGGGAATAACTGTGGGA
Page 54 of 160
Page 55 of 160
AACTACAGCTAATACCGCATGAGCCCTTCGGGGGAAAGATTTATCGCCTTTGGATCAACC
CGCGTCAGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGATCTGTAGCTGGT
CTGAGAGGATGACCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCTAGCCATGCCGCGTGAGTGATGA
CGGCCTTAGGGTTGTAAAGCTCTTTTAACAGGGACGATAATGACGGTACCTGTAGAATAA
GCCCCGGCAAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGA
ATTACTGGGCGTAAAGCGCACGTAGGCGGATTGTTAAGTCGGGGGTGAAATCCTGAGGCT
CAACCTCAGAACTGCCTTCGATACTGGCGATCTTGAGTTCGGAAGAGGTTGGTGGAACAG
Fo
CTAGTGTAGAGGTGAAATTCGTAGATATTAGCTAGAACACCAGTGGCGAAGGCGGCCAAC
TGGTCCGACACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
rP
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTCGGGGAGCTTGCTCTTTCGGTGGCGC
AGCTAACGCTTTAAGCATTTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGA
ee
ATTGACGGGGGCCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGA
ACCTTACCTGGCCTTGACATGTCGCGAACCCTGCAGAGATGCGGGAGTGCCTTCGGGAAT
rR
GCGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCC
CGCAACGAGCGCAACCCTTGTCCTTAGTTGCCA
>296-80-HRB1
iew
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Applied Microbiology and Biotechnology
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTTGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
Applied Microbiology and Biotechnology
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGATGAAGGAGTGCTCGAAAGAGAACCGTAACACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
ATTAGTTGCTA
>296-82-HRB1
Fo
AGTGGCGAACGGGTGAGTAAAGCATCGGAACGTGCCCGATCGTGGGGGATAACGCAGCGA
rP
AAGCTGCGCTAATACCGCATAAGATCTACGGATGAAAGCGGGGGACTCGCAAGAGCCTCG
CGCGAACGGAGCGGCCGATGTCAGATTAGGTAGTTGGTGGGGTAAAGGCCCACCAAGCCG
ee
ACGATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCAT
rR
GCCGCGTGCAGGAAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAGCGAAAAGGCC
CCTACTAACACTGGGGGTCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGCGC
ev
CAGCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGT
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GCGCAGGCGGTTTTGTAAGACAGAGGTGAAATCCCCGGGCTCAACCTGGGAACTGCCTTT
GTGACTGCAAAGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATG
CGTAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCTC
ATGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACG
ATGTCAACTGGTTGTTGGGTCTTAGCTGACTCAGTAACGAAGCTAACGCGTGAAGTTGAC
CGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAG
CGGTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGT
ACGGAAGTTGCCAGAGATGGCTTCGTGCTCGAAAGAGAGCCGTAACACAGGTGCTGCATG
GCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTG
CCATTAGTTGCTA
Page 56 of 160
Page 57 of 160
>296-83-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAATAACAGCGGGA
AATTGCTGCTAATACCGGATAATGACGTAAGTCCAAAGATTTATCGCCTAGGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
Fo
ATCACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGGGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
rP
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
ee
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
rR
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGATGGATCTCTTCCCTTCGGGGAC
ev
TGGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCC
CGCAACGAGCGCAACCCTCGTCCTTAGTTGCCA
>296-9-HRB1
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Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
Applied Microbiology and Biotechnology
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGCTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAACACAGGTGCTGCATGGC
Fo
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
CTTAGTTGCCA
>296-90-HRB1
rP
AGTGGCGGACGGGTGAGTAATGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
ee
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGTTGGACGGACCGATGTGCGATTAGCTAGTTGGCGGGGTAATGGCCCACCAAGGCGAC
rR
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAATTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
ev
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATG
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GGTTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGTTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGTGCCTTCGGGAATGCGAACACAGGTGCTGCATGGC
Page 58 of 160
Page 59 of 160
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTC
CTTAGTTGCCA
>296-91-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCTTGGGTTCGGAATAACAGCGAGA
AATTGCTGCTAATACCGGATGATGACGTAAGTCCAAAGATTTATCGCCCAAGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGAGGTAAAGGCTCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
Fo
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
rP
ATTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGAGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
ee
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
rR
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCGGGGCTCTTAGAGCTTCGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAAGGAA
ev
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
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Applied Microbiology and Biotechnology
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGATGGATCTCTTCCCTTCGGGGAC
TGGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCC
CGCAACGAGCGCAACCCTCGTCTTTAGTTGCCA
>318-104-HRB1
AGCGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGA
AACTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCG
CTATCAGATGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGAC
GATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATAC
CGCGTGTGTGAAGAAGGCCTTAGGGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCC
Applied Microbiology and Biotechnology
GGCGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCA
GCAGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAG
AACTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
Fo
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCT
GCGAACTTTCTAGAGATAGATTGG
>318-105-HRB1
rP
AGCGGCAGACGGGTGAGTAACACGTGGGGATCTGCCCTTTGGTACGGAATAACCCAGGGA
ee
AACTTGGACTAATACCGTATGTGCCCTTCGGGGGAAAGATTTATCGCCAAAGGATGAACC
CGCGTCGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCGTAGCTGGT
rR
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGTGTGATGA
ev
AGGCCTTAGGGTTGTAAAGCACTTTCGCCGGTGAAGATAATGACGGTAACCGGAGAAGAA
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GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCAAGCGTTGCTCGGA
ATCACTGGGCGTAAAGCGCACGTAGGCGGGTCGTTAAGTCAGAGGTGAAAGCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGGCGACCTAGAGTTCGAGAGAGGTTGGTGGAGCTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCCAAC
TGGCTCGATACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGGATGCTAGCCGTTGGGGGGTTTACCTTTCAGTGGCGCA
GCTAACGCCTTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
TTACCAGCCTTTGACATGGCAGGGCGATTTCCAGAGAT
>318-108-HRB1
Page 60 of 160
Page 61 of 160
ATTGGCGAACGGTGAATAATATATCGGAACGTGCCCAGTCGGTGGGGGGATAACGTAGAG
AAATTTACGCTAATACCGCATACGATCCAAGGGATGAAAGCGGGGGACCTTCGGGGCCTC
GTGCGACTGGAGCGGCTGATATCAGATTAGGTTGTTGGTGAGGTAAAAGCTCACCAAGCC
GACGATCTGTAGCTGGTTTGAGAGAACGACCAGCCACACTGGGACTGAGACACGGCCCAG
ACTCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGAAAGCCTGATCCAGCAA
TGCCGCGTGCAGGAAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGT
CTGCCCTAATACGGTGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTG
CCAGCAGCCGCGGTAATACGTAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCG
Fo
TGCGCAGGCGGTGATGTAAGACAAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATA
TGTGACTGCATCGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAAT
rP
GCGTAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCT
CATGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAAC
ee
GATGTCAACTGGTTGTTGGGGATTCACTTCCTCAGTAACGAAGCTAACGCGTGAAGTTGA
CCGCCTGGGGAGTACGGCCGCAAGGTTGAGACTCAAAGGAATTGACGGGGACCCGCACAA
rR
GCGGTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATG
TACGGAAGATTGCAGAGATGCGATTGT
>318-109-HRB1
iew
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Applied Microbiology and Biotechnology
AGTGGCGAACGGGTGAGTAACACGTGAGTAACCTGCCCTTGACTCTGGGATAAGCACTGG
AAACGGTGTCTAATACCGGATACGAACTTCGACGGCATCGTCAGGAGTTGGAAAGAATTT
CGGTCAAGGATGGACTCGCGGCCTATCAGCTAGTTGGTGAGGTAATGGCCCACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGTGACCGGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCAAC
GCCGCGTGAGGGACGACGGCCTTCGGGTTGTAAACCTCTTTTAGTAGGGAAGAAGCGACG
TGTTTTACACGGAGTGACGGTACCTGCAGAAAAAGCACCGGCTAACTACGTGCCAGCAGC
CGCGGTAATACGTAGGGTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAGCTCGTAGG
CGGTCTGTCGCGTCTGCTGTGAAAACTGGGGGCTCAACCCCCAGCCTGCAGTGGGTACGG
GCAGACTAGAGTGCGGTAGGGGAGATTGGAATTCCTGGTGTAGCGGTGGAATGCGCAGAT
Applied Microbiology and Biotechnology
ATCAGGAGGAACACCGATGGCGAAGGCAGATCTCTGGGCCGTAACTGACGCTGAGGAGCG
AAAGCATGGGGAGCGAACAGGATTAGATACCCTGGTAGTCCATGCCGTAAACGTTGGGAA
CTAGATGTAGGGACCATTCCACGGTTTCTGTGTCGCAGCTAACGCATTAAGTTCCCCGCC
TGGGGAGTACGGCCGCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGC
GGAGCATGCGGATTAATTCGATGCAACGCGAAGAACCTTACCAAGGCTTGACATATACCG
GAAAAGGCTGGAAACAGTCTCCC
>318-110-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAACAACAGCGAGA
Fo
AATTGCTGCTAATACCGGATAATGACGTAAGTCCAAAGATTTATCGCCTAGGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCTTAGCTGGT
rP
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
ee
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
rR
ATTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGGGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
ev
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
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TGGACTGGTATTGACGCTGAGGTGCGAAAGTGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGAT
>318-111-HRB1
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
Page 62 of 160
Page 63 of 160
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
Fo
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
rP
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGAT
>318-112-HRB1
ee
GCAGACGGGTGAGTAACGCGTGGGGAACCTACCTCTTTGTGGGGAATAACGCTCCGAAAG
rR
GAGTGGTAATACCGCATGAGACCTTCAGCTGGGATGCTGGAGGTGAAACCTGGGGACCAG
CAATGGCCTGGGGCAAGGAGAGGGTCCTGCGTCTGATTAGCTAGTTGGCGGGGTAATGGC
ev
CCACCAAGGCATCGATCAGTAGCCGGCCTGAGAGGGTGATCGGCCACACTGGAACTGAGA
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Applied Microbiology and Biotechnology
CACGGTCCAGACTCCTACGGGGGGCAGCAGTGGGGAATTTTGCGCAATGGGCGAAAGCCT
GACGCAGCAACGCCGCGTGGGTGATGAAGGTCTTCGGATTGTAAAACCCTGTCGTCAGGG
ACGAAGGTGCACATGTTAATAGCGTGTGTGCTTGACGGTACCTGGAGAGGAAGCCCCGGC
TAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGGGGCAAGCGTTATTCGGAATTATTGG
GCGTAAAGGGCGCGTAGGCGGTTTTTTAAGTCAGATGTGTAATCCCCGAGCTTAACTTGG
GAACTGCATCCGAGACTGGAAGGCTAGAGTACTGGAGAGGGTGGTGGAATTCCTCGTGTA
GCGGTGAAATGCGTAGAGATGAGGAGGAACACCAGTGGCGAAGGCGGCCACCTGGACAGT
AACTGACGCTGAGGCGCGAAAGTGTGGGTAGCAAACAGGATTAGATACCCTGGTAGTCCA
CGCTGTAAACGATGAACACTTGGTGTGGAGGGAGTTGACCCCTTCCGTGCCGGAGCTAAC
GCGTTAAGTGTTCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAAGGAATTGACGG
Applied Microbiology and Biotechnology
GGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAAGAACCTTACCT
GGGCTTGAACTGCAGTGGACCGGTGCAGAGATGT
>318-113-HRB1
AGCGGCAGACGGGTGAGTAACGCGTGGGAACGTACCTTTTGGTTCGGAACAACACAGGGA
AACTTGTGCTAATACCGGATAAGCCCTTACGGGGAAAGATTTATCGCCGAAAGATCGGCC
CGCGTCTGATTAGCTAGTTGGTGAGGTAACGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
Fo
AGGCCCTAGGGTTGTAAAGCTCTTTTGTGCGGGAAGATAATGACGGTACCGCAAGAATAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
rP
ATCACTGGGCGTAAAGGGTGCGTAGGCGGGTCTTTAAGTCAGAGGTGAAATCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGAGGATCTTGAGTTCGGGAGAGGTGAGTGGAACTG
ee
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCCCGATACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
rR
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTTGGGGAGTTTACTCTTCAGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
ev
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAACC
TTACCAGCCCTTGACATCCC
>318-115-HRB1
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AGCGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGA
AACTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCG
CTATCAGATGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGAC
GATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATAC
CGCGTGTGTGAAGAAGGCCTTAGGGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCC
GGCGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCA
GCAGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
Page 64 of 160
Page 65 of 160
GTAGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAG
AACTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCT
GCGAACTTTCTAGAGATAGATTGGT
>318-116-HRB1
Fo
AGTGGCGCACGGGTGAGTAACGCGTGAGAACCTGCCCTTTTGTTCGGAATAACGTTGGGA
rP
AACTGACGCTAATACCGGATACGCCCTTCGGGGGAAAGATTTATCGCAGAAGGAGGGGCC
CGCGTCAGATTAGCTAGTTGGTGGGGTAATGGCCTACCAAGGCGATGATCTGTAGCTGGT
ee
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
rR
AGGCCTTAGGGTTGTAAAGCTCTTTCGCACGCGACGATGATGACGGTAGCGTGAGAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGA
ev
ATTACTGGGCGTAAAGGGCGCGTAGGCGGTTTATCAAGTCAGGCGTGAAAGCTCCGGGCT
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Applied Microbiology and Biotechnology
CAACCTGGGAATTGCGTTTGATACTGGTAGACTTGAGTTCGGGAGAGGTGAGTGGAATTC
CCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGTGGCGAAGGCGGCTCAC
TGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGTGCGCTAGACGCTGGGAAACTTAGTTTTCCGGTGTCGC
AGCTAACGCATTAAGCGCACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAAGGAA
TTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAAC
CTTACCAACCCTTGACATGGGAAGTATGGTCCCC
>318-120-HRB1
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
Applied Microbiology and Biotechnology
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGAAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
Fo
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
rP
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
ee
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGT
>318-124-HRB1
rR
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGACAACGTTTCGA
ev
AAGGAACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
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CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGAGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGTGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCATTA
ACCTAATACGTTGGTGTCTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATCCAA
AACTGGCGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAGGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
Page 66 of 160
Page 67 of 160
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATGGGT
>318-126-HRB1
AGTGGCGGACGGGTGAGTAACACGTGGGAACGTGCCCTTTGGTTCGGAACAACTCAGGGA
AACTTGAGCTAATACCGGATGTGCCCTTCGGGGGAAAGATTTATCGCCATTGGAGCGGCC
CGCGTTGGATTAGCTAGTTGGTGGGGTAAAGGCCCACCAAGGCTACGATCCATAGCTGGT
Fo
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTTAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCCATGCCGCGTGAATGATGA
rP
AGGTCTTAGGATTGTAAAATTCTTTCAGCGGGGACGATAATGACGGTACCCGCAGAAGAA
GCTCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ee
ATTACTGGGCGTAAAGGGCGCGTAGGCGGATGTTTAAGTCAGAGGTGAAAGCCCAGGGCT
CAACCTTGGAAATGCCTTTGATACTGGACATCTTGAGTATGGGAGAGGTGAGTGGAACTC
rR
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTCAC
TGGCCCATTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
ev
GTAGTCCACGCTGTAAACGATGAGTGCTAGTTGTCGGCATGCATGCATGTCGGTGACGCA
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Applied Microbiology and Biotechnology
GCTAACGCATTAAGCACTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
TTACCACCTTTTGACATGCCTGGACCGCCGGAGAGATCCGGTT
>318-127-HRB1
AGTGGCAGACGGGTGAGTAACGCGTGGGAACCTACCTCAAGGTACGGAACAACCAAGGGA
AACTTTGGCTAATACCGTATGTGCCCGAGAGGGGAAAGATTTATCGCCTTGGGATGGGCC
CGCGTAGGATTAGCTAGTTGGTGAGGTAATGGCTCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGACCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGTGTGATGA
AGGCCTTAGGGTTGTAAAGCACTTTCGCCGATGAAGATAATGACGGTAGTCGGAGAAGAA
Applied Microbiology and Biotechnology
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCAAGCGTTGTTCGGA
TTTACTGGGCGTAAAGCGTACGTAGGCGGATATTTAAGTCAGGGGTGAAATCCCGAGGCT
CAACCTCGGAACTGCCTTTGATACTGGGTATCTTGAGTCCGAGAGAGGTGAGTGGAACTC
CTAGTGTAGAGGTGAAATTCGTAGATATTAGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCTCGGAACTGACGCTGAGGTACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGGATGCTAGCCGTCGGGAAGCTTGCTTCTCGGTGGCGCA
GCTAACGCATTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
Fo
TTACCAGCTCTTGACATGTCACGTATGGTTACCGGAG
>318-136-HRB1
rP
AGTGGCGAACGGGTGAGTAACACGTGAGTAACCTGCCCTTGACTCTGGGATAAGCACTGG
AAACGGTGTCTAATACCGGATACGAACTTCGACGGCATCGTCAGGAGTTGGAAAGAATTT
ee
CGGTCAAGGATGGACTCGCGGCCTATCAGCTAGTTGGTGAGGTAATGGCCCACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGTGACCGGCCACACTGGGACTGAGACACGGCCCAGA
rR
CTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCAAC
GCCGCGTGAGGGACGACGGCCTTCGGGTTGTAAACCTCTTTTAGTAGGGAAGAAGCGACG
ev
TGTTTTACACGGAGTGACGGTACCTGCAGAAAAAGCACCAGCTAACTACGTGCCAGCAGC
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CGCGGTAATACGTAGGGTGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAGCTCGTAGG
CGGTCTGTCGCGTCTGCTGTGAAAACTGGGGGCTCAACCCCCAGCCTGCAGTGGGTACGG
GCAGACTAGAGTGCGGTAGGGGAGATTGGAATTCCTGGTGTAGCGGTGGAATGCGCAGAT
ATCAGGAGGAACACCGATGGCGAAGGCAGATCTCTGGGCCGTAACTGACGCTGAGGAGCG
AAAGCATGGGGAGCGAACAGGATTAGATACCCTGGTAGTCCATGCCGTAAACGTTGGGAA
CTAGATGTAGGGACCATTCCACGGTTTCTGTGTCGCAGCTAACGCATTAAGTTCCCCGCC
TGGGGAGTACGGCCGCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGC
GGAGCATGCGGATTAATTCGATGCAACGCGAAGAACCTTACCAAGGCTTGACATATACCG
GAAAAGGCTGGAAACAGTCTCCC
>318-138-HRB1
Page 68 of 160
Page 69 of 160
AGTGGCGAACGGGTGAGTAAAGCATCGGAACGTGCCCGATCGTGGGGGATAACGCAGCGA
AAGCTGCGCTAATACCGCATAAGATCTACGGATGAAAGCGGGGGACTCGCAAGAGCCTCG
CGCGAACGGAGCGGCCGATGTCAGATTAGGTAGTTGGTGGGGTAAAGGCCCACCAAGCCG
ACGATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCAT
GCCGCGTGCAGGAAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAGCGAAAAGGCC
CCTACTAACACTGGGGGTCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGC
CAGCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGT
Fo
GCGCAGGCGGTTTTGTAAGACAGAGGTGAAATCCCCGGGCTCAACCTGGGAACTGCCTTT
GTGACTGCAAAGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATG
rP
CGTAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCTC
ATGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACG
ee
ATGTCAACTGGTTGTTGGGTCTTAGCTGCCTCAGTAACGAAGCTAACGCGTGAAGTTGAC
CGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAG
rR
CGGTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGT
ACGGAAGTTGCCAGAGATGGCTTCGT
>318-141-HRB1
iew
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Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGCCTCGCGC
GGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGACG
ATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACTC
CTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGCC
GCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATTG
GCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCAG
CAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGCG
TAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGAA
ACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCGT
Applied Microbiology and Biotechnology
AGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAAG
CACGAAGGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGATG
CGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGCC
GCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGTC
GCGAATCCTGCAGAGATGCGGGAGT
>318-142-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTGGGTTCGGAATAACAGCGAGA
Fo
AATTGCTGCTAATACCGGATGATGACGAAAGTCCAAAGATTTATCGCCCAGGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGGGGTAAAGGCTCACCAAGGCGACGATCCTTAGCTGGT
rP
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
ee
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
rR
ATTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGAGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
ev
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
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TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGAT
>318-144-HRB1
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTTGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
Page 70 of 160
Page 71 of 160
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
Fo
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACAGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
rP
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGAT
>318-147-HRB1
ee
CGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGAAA
rR
CTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCGCT
ATCAGATGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGA
ev
TCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCC
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Applied Microbiology and Biotechnology
TACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATACCG
CGTGTGTGAAGAAGGCCTTAGGGTTGTAGAGCACTTTCAGTGGGGAGGAAAAGTTGCCGG
CGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCAGC
AGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGT
AGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAGAA
CTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCGTA
GAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAGGT
GCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGT
CAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACCGC
CTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGG
Applied Microbiology and Biotechnology
TGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCTGC
GAACTTTCTAGAGATAGATTGGT
>318-150-HRB1
AGTGGCGGACGGGTGAGTAACACGTGGGAACGTGCCCTTTGGTTCGGAACAACTCAGGGA
AACTTGAGCTAATACCGGATGTGCCCTTCGGGGGAAAGATTTATCGCCATTGGAGCGGCC
CGCGTTGGATTAGCTAGTTGGTGGGGTAAAGGCCCACCAAGGCTACGATCCATAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTTAGGAATCCTGCGCAATGGGCGAAAGCCTGACGCAGCCATGCCGCGTGAATGATGA
Fo
AGGTCTTAGGATTGTAAAATTCTTTCAGCGGGGACGATAATGACGGTACCCGCAGAAGAA
GCTCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
rP
ATTACTGGGCGTAAAGGGCGCGTAGGCGGATGTTTAAGTCAGAGGTGAAAGCCCAGGGCT
CAACCTTGGAAATGCCTTTGATACTGGACATCTTGAGTATGGGAGAGGTGAGTGGAACTC
ee
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTCAC
TGGCCCATTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
rR
GTAGTCCACGCTGTAAACGATGAGTGCTAGTTGTCGGCATGCATGCATGTCGGTGACGCA
GCTAACGCATTAAGCACTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
ev
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
TTACCACCTTTTGACATGCCTGGACCGCCGGAGAGATCCGGTT
>318-152-HRB1
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AGTGGCGCACGGGTGAGTAACACGTGACTAACCTACCCTGGAGTGGGGAATAACTGAGGG
AAACCTTAGCTAATACCGCATAACACCTACGGGTCAAAGGAGCAATTCGCTTCAGGAGGG
GGTCGCGGCCGATTAGTTAGTTGGCGGGGTAATGGCCCACCAAGACGATGATCGGTATCC
GGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
CAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGGA
TGAAGTACTTCGGTACGTAAACTCCTTTCGATCGGGACGATAATGACGGTACCGAGAGAA
GAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCGAGCGTTGTTC
GGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTTTGGTAAGTCTTGTGTGAAATCTATGG
Page 72 of 160
Page 73 of 160
GCTCAACTCATAGTCTGCACGAGAAACTGCCGGGCTTGAGTATGGAAGAGGTGAGTGGAA
TTCCTGGTGTAGCGGTGAAATGCGTAGATATCAGGAGGAACACCTGTGGCGAAAGCGGCT
CACTGGACCATAACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATACC
CTGGTAGTCCTAGCCCTAAACGATGACTGCTTGGTGTGACGGGTACCCAATCCCGCCGTG
CCGTAGCTAACGCGTTAAGCAGTCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAA
GGGATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAA
GAACCTTACCTGGGCTCGAAATGTTATGGACCGCGGTAGAAATATCGCTTT
>318-153-HRB1
Fo
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAATAACAGCGAGA
AATTGCTGCTAATACCGGATAATGACGTAAGTCCAAAGATTTATCGCCTAGGGATGAGCC
rP
CGCGTAGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
ee
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
rR
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
ACTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGGGGTGAAAGCCTGGAGCT
ev
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
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Applied Microbiology and Biotechnology
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGAT
>318-154-HRB1
AGTGGCGGACGGGTGAGTAATGCGTAGGAATCTGTCTTTTAGTGGGGGACAACCCAGGGA
AACTTGGGCTAATACCGCATGAGCCCTGAGGGGGAAAGCGGGGGATCTTCGGACCTCGCG
CTAAGAGAGGAGCCTACGTCCGATTAGCTAGTTGGCGGGGTAAAGGCCCACCAAGGCGAC
Applied Microbiology and Biotechnology
GATCGGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTTCGCAATGGGGGCAACCCTGACGAAGCAATGC
CGCGTGGATGAAGAAGGCCTTCGGGTTGTAAAGTCCTTTCGTGGAGGACGAAAAGGTGGG
TTCTAATACAATCTGCTATTGACGTGAATCCAAGAAGAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGGGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGGGTGC
GTAGGCGGTACGTTAGGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGGTAGA
AACCGGCGCACTAGAGTATGGGAGAGGGTGGTGGAATTCCAGGTGTAGCGGTGAAATGCG
TAGATATCTGGAGGAACATCAGTGGCGAAGGCGGCCACCTGGCCCAATACTGACGCTGAG
Fo
GCACGAAAGCGTGGGGAGCAGACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GAATACTAGATGTTTGGTGCCTAGCGTACTGAGTGTCGTAGCTAACGCGATAAGTATTCC
rP
GCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGGCTTGACATGTC
CGGAATTCTGCAGAGAT
rR
>318-155-HRB1
ee
AGTGGCGGACGGGTGAGTAACACGTGGGAACGTGCCCTTTGGTTCGGAACAACTCAGGGA
AACTTGAGCTAATACCGGATGTGCCCTTCGGGGGAAAGATTTATCGCCATTGGAGCGGCC
ev
CGCGTTGGATTAGCTAGTTGGTGGGGTAAAGGCCCACCAAGGCTACGATCCATAGCTGGT
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CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTTAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCCATGCCGCGTGAATGATGA
AGGTCTTAGGATTGTAAAATTCTTTCAGCGGGGACGATAATGACGGTACCCGCAGAAGAA
GCTCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ATTACTGGGCGTAAAGGGCGCGTAGGCGGATGTTTAAGTCAGAGGTGAAAGCCCAGGGCT
CAACCTTGGAAATGCCTTTGATACTGGACATCTTGAGTATGGGAGAGGTGAGTGGAACTC
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTCAC
TGGCCCATTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCTGTAAACGATGAGTGCTAGTTGTCGGCATGCATGCATGTCGGTGACGCA
GCTAACGCATTAAGCACTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
Page 74 of 160
Page 75 of 160
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
TTACCACCTTTTGACATGCCTGGACCGCCGGAGAGATCCGGTT
>318-160-HRB1
AGTGGCGAACGGGTGAAGTAATATATCGGAACGTGCCCAGTCGTGGGGGATAACGTAGAG
AAATTTACGCTAATACCGCATACGATCCAAGGATGAAAGCGGGGGACCTTCGGGCCTCGT
GCGACTGGAGCGGCTGATATCAGATTAGGTTGTTGGTGAGGTAAAAGCTCACCAAGCCGA
CGATCTGTAGCTGGTTTGAGAGAACGACCAGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGAAAGCCTGATCCAGCAATG
Fo
CCGCGTGCAGGAAGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGGTCT
GCCCTAATACGGTGGGCCCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCC
rP
AGCAGCCGCGGTAATACGTAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGTG
CGCAGGCGGTGATGTAAGACAAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATATG
ee
TGACTGCATCGCTGGAGTGCGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGC
GTAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGCACTGACGCTCA
rR
TGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGA
TGTCAACTGGTTGTTGGGGATTCACTTCCTCAGTAACGAAGCTAACGCGTGAAGTTGACC
ev
GCCTGGGGAGTACGGCCGCAAGGTTGAGACTCAAAGGAATTGACGGGGACCCGCACAAGC
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Applied Microbiology and Biotechnology
GGTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTA
CGGAAGATTGCAGAGATGCGATTGT
>318-161-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAATAACAGCGAGA
AATTGCTGCTAATACCGGATAATGACGTAAGTCCAAAGATTTATCGCCTAGGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
Applied Microbiology and Biotechnology
ACTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGGGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGAT
>318-162-HRB1
Fo
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
rP
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTTGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
ee
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
rR
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
ev
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
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GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
CCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGAT
>318-163-HRB1
AGTGGCGAACGGGTGAGTAACACATCGGAACGTGCCCGATCGTGGGGGATAACGGAGCGA
Page 76 of 160
Page 77 of 160
AAGCTTTGCTAATACCGCATACGATCTACGGATGAAAGCAGGGGACCCTTGGGCCTTGCG
CGGACGGAGCGGCCGATGGCAGATTAGGTAGTTGGTGGGATAAAAGCTTACCAAGCCGAC
GATCTGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
CGCGTGCAGGATGAAGGCCTTCGGGTTGTAAACTGCTTTTGTACGGAACGAAAAGACTCC
TTCTAATAAAGGGGGTTCATGACGGTACCGTAAGAATAAGCACCGGCTAACTACGTGCCA
GCAGCCGCGGTAATACGTAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GCAGGCGGTTATATAAGACAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTTGT
Fo
GACTGTATAGCTGGAGTACGGCAGAGGGGGATGGAATTCCGCGTGTAGCAGTGAAATGCG
TAGATATGCGGAGGAACACCGATGGCGAAGGCAATCCCCTGGGCCTGTACTGACGCTCAT
rP
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GTCAACTGGTTGTTGGGAATTCACTTTCTCAGTAACGAAGCTAACGCGTGAAGTTGACCG
ee
CCTGGGGAGTACAGCCGCAAGGTTGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCG
GTGGATGATGTGGTTTAATTCGATGCAACGCGAAAAACCTTACCCACCTTTGACATGTAC
GGAATCCTTCAGAGAT
ev
>318-164-HRB1
rR
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
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Applied Microbiology and Biotechnology
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGCCTCGCGC
GGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGACG
ATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACTC
CTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGCC
GCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATTG
GCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCAG
CAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGCG
TAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGAA
ACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCGT
AGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAAG
Applied Microbiology and Biotechnology
CACGAAGGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGATG
CGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGCC
GCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
GGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGTC
GCGAATCCTGCAGAGATGCGGGAGT
>318-167-HRB1
AGCGGCAGACGGGTGAGTAACGCGTGGGAACGTACCTTTTGGTTCGGAACAACACAGGGA
AACTTGTGCTAATACCGGATAAGCCCTTACGGGGAAAGATTTATCGCCGAAAGATCGGCC
Fo
CGCGTCTGATTAGCTAGTTGGTGAGGTAACGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
rP
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
AGGCCCTAGGGTTGTAAAGCTCTTTTGTGCGGGAAGATAATGACGGTACCGCAAGAATAA
ee
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ATCACTGGGCGTAAAGGGTGCGTAGGCGGGTCTTTAAGTCAGAGGTGAAATCCTGGAGCT
rR
CAACTCCAGAACTGCCTTTGATACTGAGGATCTTGAGTTCGGGAGAGGTGAGTGGAACTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
ev
TGGCCCGATACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
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GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTTGGGGAGTTTACTCTTCAGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAACC
TTACCAGCCCTTGACATCCC
>318-172-HRB1
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTGCCCCTTGGTTCGGAATAACAGCGAGA
AATTGCTGCTAATACCGGATAATGACGTAAGTCCAAAGATTTATCGCCTAGGGATGAGCC
CGCGTAGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
Page 78 of 160
Page 79 of 160
AGGCCTTAGGGTTGTAAAGCTCTTTTACCCGGGATGATAATGACAGTACCGGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTATTCGGA
ACTACTGGGCGTAAAGCGCACGTAGGCGGCTTTGTAAGTTAGGGGTGAAAGCCTGGAGCT
CAACTCCAGAATTGCCTTTAAGACTGCATCGCTTGAATCCAGGAGAGGTGAGTGGAATTC
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGACTGGTATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGCTGTCTGGGCTCTTAGAGCTTAGGTGGCGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAA
Fo
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATGTCCGGACGATTTCCAGAGAT
>318-173-HRB1
rP
AGTGGCGGACGGGTGAGTAACACGTGGATAATCTGCCTATGACCCTGGGATAACACCGTG
ee
AAAATGGTGCTAATACCGGATACCTTCGAGAAGCCGCATGGTTTTTTGAAGAAAGATTTA
TCGGTCATAGATGAATCCGCGTCTGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGC
rR
GACGATCAGTAGCCGGCCTGAGAGGGTGAACGGCCACACTGGGACTGAGACACGGCCCAG
ACTCCTACGGGAGGCAGCAGTGGGGAATCTTCCGCAATGGGCGCAAGCCTGACGGAGCAA
ev
CGCCGCGTGAGTGAAGAAGGCCTTCGGGTTGTAAAACTCTGTCTTCAGGGAAGAAAAAAA
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Applied Microbiology and Biotechnology
TGACGGTACCTGAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTA
GGTGGCAAGCGTTGTCCGGAATTACTGGGCGTAAAGGGCGCGTAGGCGGATACTTAAGTC
AGATGTGAAAACTGCAGGCTTAACCTGGAGAGTGCATCTGAAACTGGATATCTTGAGTGC
AGGAGAGGACAGTGGAATTCCTAGTGTAGCGGTGAAATGCGTAGATATTAGGAGGAACAC
CAGTGGCGAAGGCGGCTGTCTGGACTGTAACTGACGCTGAGGCGCGAAAGCGTGGGGAGC
AAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGGGTACTAGGTGTAGGGGG
TATCGACCCCTTCTGTGCCGGAGTTAACACAATAAGTACCCCGCCTGGGGAGTACGGCCG
CAAGGTTGAAACTCAAAGGAATTGACGGGGGCCCGCACAGGCGGTGGAGTATGTGGTTTA
ATTCGACGCAACGCGAAGAACCTTACCAGGTCTTGACATCCTCTGACAGCTCTAGAGATA
GAGTGTT
Applied Microbiology and Biotechnology
>318-174-HRB1
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACC
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
Fo
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
rP
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
ee
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
rR
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGT
iew
>318-176-HRB1
ev
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AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGCTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTTGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
Page 80 of 160
Page 81 of 160
AACTGGCAGGCTAGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAAATTGACGGGGGCCCGCACAA
GCGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATG
TCGCGAATCCTGCAGAGATGCGGGAGT
>318-178-HRB1
Fo
GCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGAAACT
CGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCGCTAT
rP
CAGATGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGATC
CGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTA
ee
CGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATACCGCG
TGTGTGAAGAAGGCCTTAGGGTTGTAGAGCACTTTCAGTGGGGAGGAAAAGTTGCCGGCG
rR
AATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCAGCAG
CCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGTAG
ev
GCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAGAACT
iew
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Applied Microbiology and Biotechnology
GCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCGTAGA
GATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAGGTGC
GAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGTCA
ACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACCGCCT
GGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGGTG
GAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCTGCGA
ACTTTCTAGAGAT
>318-179-HRB1
AGCGGCAGACGGGTGAGTAACACGTGGGGATCTGCCCTTTGGTACGGAATAACCCAGGGA
AACTTGGACTAATACCGTATGTGCCCTTCGGGGGAAAGATTTATCGCCAAAGGATGAACC
Applied Microbiology and Biotechnology
CGCGTCGGATTAGCTAGTTGGTGTGGTAAAGGCGCACCAAGGCGACGATCCGTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGTGTGATGA
AGGCCTTAGGGTTGTAAAGCACTTTCGCCGGTGAAGATAATGACGGTAACCGGAGAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCAAGCGTTGCTCGGA
ATCACTGGGCGTAAAGCGCACGTAGGCGGGTCGTTAAGTCAGAGGTGAAAGCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGGCGACCTAGAGTTCGAGAGAGGTTGGTGGAGCTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCCAAC
Fo
TGGCTCGATACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGGATGCTAGCCGTTGGGGGGTTTACCTTTCAGTGGCGCA
rP
GCTAACGCCTTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
ee
TTACCAGCCTTTGACATGGCAGGGCGATTTCCAGAGAT
>318-180-HRB1
rR
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCCACCCAGGCGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
ev
CGGTTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
iew
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GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTGGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
AACTGGCCAGCTGGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
Page 82 of 160
Page 83 of 160
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGT
>318-181-HRB1
AGCGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGA
AACTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCG
CTATCAGATGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGAC
GATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACT
Fo
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATAC
CGCGTGTGTGAAGAAGGCCTTAGGGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCC
rP
GGCGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCA
GCAGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
ee
GTAGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAG
AACTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCG
rR
TAGAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
ev
GTCAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACC
iew
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Applied Microbiology and Biotechnology
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCT
GCGAACTTTCTAGAGATAGATTGGT
>318-182-HRB1
AGTGGCGGACGGGTGAGTAATGCGTAGGAATCTGTCTTTTAGTGGGGGACAACCCAGGGA
AACTTGGGCTAATACCGCATGAGCCCTGAGGGGGAAAGCGGGGGATCTTCGGACCTCGCG
CTAAGAGAGGAGCCTACGTCCGATTAGCTAGTTGGCGGGGTAAAGGCCCACCAAGGCGAC
GATCGGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATTTTTCGCAATGGGGGCAACCCTGACGAAGCAATGC
CGCGTGGATGAAGAAGGCCTTCGGGTTGTAAAGTCCTTTCGTGGAGGACGAAAAGGTGGG
Applied Microbiology and Biotechnology
TTCTAATACAATCTGCTATTGACGTGAATCCAAGAAGAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGGGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGGGTGC
GTAGGCGGTACGTTAGGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGGTAGA
AACCGGCGCACTAGAGTATGGGAGAGGGTGGTGGAATTCCAGGTGTAGCGGTGAAATGCG
TAGATATCTGGAGGAACATCAGTGGCGAAGGCGGCCACCTGGCCCAATACTGACGCTGAG
GCACGAAAGCGTGGGGAGCAGACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GAATACTAGATGTTTGGTGCCTAGCGTACTGAGTGTCGTAGCTAACGCGATAAGTATTCC
GCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGC
Fo
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGGCTTGACATGTC
CGGAATTCTGCAGAGAT
>318-191-HRB1
rP
GTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGAAACTCGAGCTAATACCGCATACG
ee
CCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCGCTATCAGCTGAGCCTGCGTCGGA
TTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGATCCGTAGCTGGTCTGAGAGGA
rR
TGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAGCAGTGGGGA
ATATTGGACAATGGGGGCAACCCTGATCCAGCCATACCGCGTGTGTGAAGAAGGCCTTAG
ev
GGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCCGGCGAATACCCGGCGACCGTGAC
iew
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GCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGT
GCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGTAGGCGGTTTGGTAAGCTGGAT
GTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAGAACTGCCAAGCTAGAGTATGGTA
GAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCGTAGAGATCGGAAGGAACACCAGT
GGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGTCAACTAGCCGTTGGGCTCCTT
GAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACCGCCTGGGGAGTACGGCCGCAAGG
TTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCG
ATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCTGCGAACTTTCTAGAGATAGATTG
GT
Page 84 of 160
Page 85 of 160
>318-192-HRB1
CGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGAAA
CTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCGCT
ATCAGCTGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGA
TCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCC
TACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATACCG
CGTGTGTGAAGAAGGCCTTAGGGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCCGG
CGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCAGC
Fo
AGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGT
AGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAGAA
rP
CTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCGTA
GAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAGGT
ee
GCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGT
CAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACCGC
rR
CTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGG
TGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCTGC
GAACTTTCTAGAGATAGATTGGT
iew
>318-193-HRB1
ev
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Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCTTCGGGCCTCGCG
CGGTTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
GTAGGCGGTTGGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
Applied Microbiology and Biotechnology
AACTGGCCAGCTGGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACACCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGT
>318-194-HRB1
Fo
AGTGGCGGACGGGTGAGTAAAGCATCGGGACCTACCCAGACGTGGGGGATAACGTAGGGA
AACTTACGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGACCCTCGGGCCTCGCG
rP
CGGTTGGACGGACCGATGTGCGATTAGCTGGTTGGCGGGGTAATGGCCCACCAAGGCGAC
GATCGCTAGCTGGTCTGAGAGGATGATCAGCCACACTGGAACTGAGACACGGTCCAGACT
ee
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAATGC
CGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTATCGGGAGCGAAATACCATT
rR
GGCTAATAACCGGTGGGGCTGACGGTACCCGAGGAATAAGCACCGGCTAACTTCGTGCCA
GCAGCCGCGGTAATACGAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGGGTGC
ev
GTAGGCGGTTGGTTAAGTCTGTCGTGAAATCCCCGGGCTCAACCTGGGAATGGCGATGGA
iew
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AACTGGCCAGCTGGAGTGTGTCAGAGGATGGTGGAATTCCCGGTGTAGCGGTGAAATGCG
TAGAGATCGGGAGGAACATCAGTGGCGAAGGCGGCCATCTGGGACAACACTGACGCTGAA
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGAT
GCGAACTGGATGTTGGTCTCAACTCGGAGATCAGTGTCGAAGCTAACGCGTTAAGTTCGC
CGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAG
CGGTGGAGTATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATGT
CGCGAATCCTGCAGAGATGCGGGAGT
>318-195-HRB1
CGGCGGACGGGTGCGTAACGCGTAGGAATCTGCCTGGTAGTGGGGGATAACTCGGGGAAA
CTCGAGCTAATACCGCATACGCCCCATGGGGGAAAGCGGGGGACCTTCGGGCCTCGCGCT
Page 86 of 160
Page 87 of 160
ATCAGCTGAGCCTGCGTCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGACGA
TCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCC
TACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATACCG
CGTGTGTGAAGAAGGCCTTAGGGTTGTAAAGCACTTTCAGTGGGGAGGAAAAGTTGCCGG
CGAATACCCGGCGACCGTGACGCTACCTGCAGAAGAAGCACCGGCAAACTCCGTGCCAGC
AGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGT
AGGCGGTTTGGTAAGCTGGATGTGAAAGCCCTGGGCTCAACCTGGGAACTGCATCCAGAA
CTGCCAAGCTAGAGTATGGTAGAGGACAGTGGAATTTCCGGTGTAGCGGTGAAATGCGTA
Fo
GAGATCGGAAGGAACACCAGTGGCGAAGGCGACTGTCTGGACCAATACTGACGCTGAGGT
GCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGT
rP
CAACTAGCCGTTGGGCTCCTTGAGGGTCTAGTGGCGCAGCTAACGCGATAAGTTGACCGC
CTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGG
ee
TGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCAGGCCTTGACATCCTGC
GAACTTTCTAGAGATAGATTGGT
iew
>295-10-HRB2
ev
From HRB2:
rR
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Applied Microbiology and Biotechnology
AGTGGCGACCGGGTGAGTAACACGTGACTAACCTACCCTCGAGTGTGGAATAACATCGGG
AAACCGATGCTAATACCGCATAACATCGGCGCTCTAATAAGTGCCGATCAAAGGAGTAAT
CCGCTTGAGGAGGGGGTCGCGGCTGATTAGCTAGTTGGCGGGGTAACGGCCCGCCAAGGC
GAAGATCGGTAGCCGGCCTGAGAGGGCGCACGGCCACACTGGAACTGAAACACGGTCCAG
ACTCCTACGGGAGGCAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAA
CGCCGCGTGGAGGATGAAGCCCCTTGGGGCGTAAACTCCTTTCGACCAAGACGATAATGA
CGGTACTGGTGGAAGAAGCACCGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGG
TGCAAGCGTTGTTCGGAATTATTGGGCGTAAAGGGTGCGTAGGCGGCGCGGTAAGTCACC
Applied Microbiology and Biotechnology
TGTGAAATCTCCAAGCTTAACTTGGAGCCTGCAGGCGAAACTGCCGTGCTGGAGTATGGG
AGAGGTGCGTGGAATTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTG
TGGCGAAAGCGGCGCACTGGACCATAACTGACGCTGATGCACGAAAGCTAGGGGAGCAAA
CAGGATTAGATACCCTGGTAGTCCTAGCCCTAAACGATGATTGCTTGGTGTGGTGGGTAC
CCAATCCCACTGTGCCGTAGCTAACGCGATAAGCAATCCGCCTGGGGAGTACGGTCGCAA
GGCTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATT
CGACGCAACGCGAAGAACCTTACCTGGGCTCGAAATGTAGTGGAATCGGGTGGAAACATC
CGCGTCTCGCAAGAGACTGCTATATAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGA
Fo
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATCCCTAGTTGCCA
>295-12-HRB2
rP
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGAA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
ee
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
rR
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAGGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
ev
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
iew
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GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
Page 88 of 160
Page 89 of 160
TTAGTTACCA
>295-14-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAACCTGCCCCTGGCTCTGGGATAGCCTCCGG
AAACGGGGATTAATACTGGATATTCACTGCTTCCTGCATGGGGGGTGGTGGAAAGTTTTT
CGGTCAGGGTGGGGCTCGCGGCCTATCAGCTTGTTGGGGGGGTGACGGCCCACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGGAAGCCTGACGCAGCGAC
GCCGCGTGCGGGATGAAGGCCTTCGGGTTGTAAACCGCTTTCACCAGGGACGAAGCTAAC
Fo
GTGACGGTACCTGGGGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGT
AGGGCGCGAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGCTGGTTGCGT
rP
CTGCTGTGAAATCCCGGGGCTTAACCCCGGGCGTGCAGTGGATACGGGCCGGCTGGAGGC
AGGCAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
ee
CCGGTGGCGAAGGCGGTTCTCTGGGCCTGTACTGACGCTGAGGAGCGAAAGCGTGGGGAG
CAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGTC
rR
CCTTCCACGGGGTCTGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
ev
AATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGGCCGGAAAACTCGCAGAGA
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Applied Microbiology and Biotechnology
TGCGGGGTCCTTCGGGGCCGGTCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCCATGTTGCCA
>295-18-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAATCTGCCCTTAGCTTCGGGATAGCTCCGGG
AAACCGGAATTAATACCGGATATGACTATGGCCGACATCAGCCATGGTGGAAAGTTTTTC
GGCTAGGGATGAGCTCGCGGCCTATCAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCGA
CGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGAAAGCCTGACGCAGCGACG
CCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAAAG
TGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGTA
Applied Microbiology and Biotechnology
GGGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGTCTGCCACGT
CCGCTGTGAAAACCTAGGGCTTAACCCTGGGCCTGCAGTAGATACGGGCAGACTAGAGGT
AGGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
CCGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAG
CAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGGT
CCTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
AATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGA
Fo
TATGGTGTCCGTAAGGGCCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCTATGTTGCCA
>295-19-HRB2
rP
AGTGGCGGACGGGTGAGTAATGCCTGGGAAACTGCCCGATGGAGGGGGATAACCACTGGA
ee
AACGGTAGCTAATACCGCATAACGTCTTCGGACCAAAGTGGGGGACCTTCGGGCCTCACA
CCATCGGATGTGCCCAGGTGGGATTAGCTAGTAGGTGGGGTAATGGCTCACCTAGGCGAC
rR
GATCCCTAGCTGGTCTGAGAGGATGACCAGCCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCCATGC
ev
CGCGTGTATGAAGAAGGCCTTCGGGTTGTAAAGTACTTTCAGTGGGGAGGAAGGCGATGA
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GGTTAATAGCCTCGTCGATTGACGTTACCCGCAGAAGAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCAC
GCAGGCGGTCTGTCAAGTCGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCGA
AACTGGCAGACTAGAGTCTTGTAGAGGGGGGTAGAATTCCAGGTGTAGCGGTGAAATGCG
TAGAGATCTGGAGGAATACCGGTGGCGAAGGCGGCCCCCTGGACAAAGACTGACGCTCAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCGACTTGGAGGTTGTGCCCTTGAGGCGTGGCTTCCGGAGCTAACGCGTTAAGTCGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAGCTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGCCTTGACATCCA
CGGGATTCGGCAGAGATGCCTTAGTGCCTTCGGGAACCGTGAGACAGGTGCTGCATGGCT
Page 90 of 160
Page 91 of 160
GTCGTCAGCTCGTGTTGTGAAATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATCC
TTTGTTGCCA
>295-20-HRB2
AGTGGCGCACGGGTGAGTAGCGCGTGGGAACCTGCCCTGGAGTGGGGGATAACCGAGGGA
AACTTCGGCTAATACCGCATACGCCGGTGGTCTCGAGAGAGACGGCCGGGAAAGATTTAT
CGCTCTAGGAGGGGCCCGCGTCGGATTAGGTAGTTGGTGGGGTAACGGCCTGCCAAGCCT
GTGATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAAT
Fo
GCCGCGTGAGTGATGAAGGCCTTCGGGTTGTAAAGCTCTTTCGCACGCGAGGATGATGAC
GGTAGCGTGAGAAGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGG
rP
GCGAGCGTTGTTCGGATTTACTGGGCGTAAAGGGCGCGTAGGCGGTGCTTCAAGTCAGGC
GTGAAAGCCCCGGGCTCAACCTGGGAACGGCGCTTGGGACTGGGGCACTGGAGTTCGGGA
ee
GAGGAGCGTGGAATTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGT
GGCGAAGGCGGCGCTCTGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAAC
rR
AGGATTAGATACCCTGGTAGTCCACGCGGTAGACGATGTGTGCTAGACGTTGGGGGGCCT
AGCTCCCCGGTGTCGCCGCTAACGCTTTAAGCACACCGCCTGGGGAGTACGGCCGCAAGG
ev
TTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCG
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Applied Microbiology and Biotechnology
ACGCAACGCGAAGAACCTTACCAGCCCTTGACATGCCTCGTATGGGGCCGAGAGATCGGC
TTCTTCGGTTCGGCCGGCGGGGACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTG
AGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCATCCCCAGTTGCCA
>295-24-HRB2
AGTGGCGCACGGGTGAGTAACACGTGACTAGCCTACCCTGGAGTGGGGGATAACTGAGGG
AAACCTTAGCTAATACCGCATAATACCCACGGGTCAAAGGAGCAATTCGCTTTGGGAGGG
GGTCGCGGCCGATTAGTTAGTTGGCGGGGTAACGGCCCACCAAGACGATGATCGGTATCC
GGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
CAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAGCGCCGCGTGGAGGA
TGAAGTCCTTCGGGACGTAAACTCCTTTCGATCGGGACGATAATGACGGTACCGGAAGAA
Applied Microbiology and Biotechnology
GAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCGAGCGTTGTTC
GGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTTTGGTAAGTCTTATGTGAAATCTATGG
GCTCAACTCATAGACTGCATGAGAAACTGCCGGGCTTGAGTGTGGGAGAGGTGAGTGGAA
TTTCCGGTGTAGCGGTGAAATGCGTAGATATCGGAAGGAACACCTGTGGCGAAAGCGGCT
CACTGGACCACAACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATACC
CTGGTAGTCCTAGCCCTAAACCATGACTGCTTGGTGTGACGGGTACCCAATCCCGCCGTG
CCGTAGCTAACGCGTTAAGCAGTCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAA
GGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAA
Fo
GAACCTTACCTGGGCTCGAAATGTTGTGGACCGGGGTAGAAATATCCCTTCCCCGCAAGG
GGCCGCAATATAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAG
rP
TCCCGCAACGAGCGCAACCCTTATCTTCAGTTGCTA
>295-26-HRB2
ee
AGTGGCGCACGGGTGAGTAGCGCGTGGGAACCTGCCCCGGAGTGGGGGATAACCGAGGGA
AACTTCGGCTAATACCGCATACGCCGGTGGTCTCGAGAGAGACGGCCGGGAAAGATTTAT
rR
CGCTCTAGGAGGGGCCCGCGTCGGATTAGGTAGTTGGTGGGGTAACGGCCTACCAAGCCT
GTGATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGA
ev
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAAT
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GCCGCGTGAGTGATGAAGGCCTTCGGGTTGTAAAGCTCTTTCGCACGCGAGGATGATGAC
GGTAGCGTGAGAAGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGG
GCGAGCGTTGTTCGGATTTACTGGGCGTAAAGGGCGCGTAGGCGGTGCTTCAAGTCAGGC
GTGAAAGCCCCGGGCTCAACCTGGGAACGGCGCTTGGGACTGGGGCACTGGAGTTCGGGA
GAGGAGCGTGGAATTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGT
GGCGAAGGCGGCGCTCTGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCGGTAAACGATGTGTGCTAGACGTTGGGGGGCCT
AGCTCCCCGGTGTCGCCGCTAACGCTTTAAGCACACCGCCTGGGGAGTACGGCCGCAAGG
TTAAAACTCAAAGGAATTGACGGGGGCCCCGCACAAGCGGTGGAGCATGTGGTTTAATTC
GACGCAACGCGAAGAACCTTACCAGCCCTTGACATGCCTCGTATGGGGCCGAGAGATCGG
Page 92 of 160
Page 93 of 160
CTTCTTCGGTTCGGCCGGCGGGGACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGT
GAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCATCCCCAGTTGCCA
>295-3-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
Fo
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
rP
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
ee
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
rR
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
ev
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
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Applied Microbiology and Biotechnology
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-31-HRB2
AGCGGCAGACGAGTGAGTAACGCGTGGGAACGTACCTTTTGGTTCGGAACAACACAGGGA
AACTTGTGCTAATACCGGATAAGCCCTTACGGGGAAAGATTTATCGCCGAAAGATCGGCC
CGCGTCTGATTAGCTAGTTGGTGAGGTAATGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
Applied Microbiology and Biotechnology
AGGCCCTAGGGTTGTAAAGCTCTTTTGTGCGGGAAGATAATGACGGTACCGCAAGAATAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ATCACTGGGCGTAAAGGGTGCGTAGGCGGGTCTTTAAGTCAGGGGTGAAATCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGAGGATCTTGAGTTCGGGAGAGGTGAGTGGAACTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCCCGATACTGACGCTGAGGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGAATGCCAGCCGTTAGTGGGTTTACTCACTAGTGGCGCA
GCTAACGCTTTAAGCATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
Fo
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGCAGAACC
TTACCAGCCCTTGACATCCCGGTCGCGGACTCCAGAGACGGAGTTCTTCAGTTCGGCTGG
rP
ACCGGAGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTC
CCGCAACGAGCGCAACCCCCGTCCTTAGTTGCTA
>295-32-HRB2
ee
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
rR
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
ev
GATCCGTAACTGGTCTGAGCGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
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CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGGGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
Page 94 of 160
Page 95 of 160
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-33-HRB2
AGCGGCGAACGGGTGGGTAACACGTGAGTAACCTGCCCCTAGCTCTGGGATAGCTCCGGG
AAACCGGGATTAATACCAGATACGACCACTTTAGACATCTGTCGTGGTGGAAAGGATTCC
GGCTAGGGATGGGCTCGCGGCCTATCAGCTTGTTGGTGGGGTAACGGCCTACCAAGGCGA
Fo
CGACGGGTAGCCGGCCTGAGAGGGGGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGAAAGCCTGACGCAGCGACG
rP
CCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAGAG
TGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGTA
ee
GGGCGCAAGCGCTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGTCTGTTGCGT
CCGCTGTGAAATCTCGGGGCTTAACCCCGAGCCTGCAGTGGATACGGGCAGACTAGAGGT
rR
AGGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
CCGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAG
ev
CAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGTTGGGCGCTAGGTGTGGGAT
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Applied Microbiology and Biotechnology
CCTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
AATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGA
TACGGTGTCCGTAAGGGTCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCTATGTTGCCA
>295-36-HRB2
AGCGGCGGACGGGTGAGTAACACGTAGGTAACCTGCCACTCAGACTGGGATAACTACCGG
AAACGGTAGCTAAGACCGGATACGCTTAAAGGAGGGCATCCTCTTTTAAGGAAAAGCGGA
GCAATCTGCTGCTGAATGATGGACCTGCGGCGCATTAGCTAGTTGGTGAGGTAGCGGCTC
ACCAAGGCGACGATGCGTAGCCGACCTGAGAGGGTGAACGGCCACACTGGGACTGAGACA
Applied Microbiology and Biotechnology
CGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATCTTCGGCAATGGACGGAAGTCTGA
CCGAGCAACGCCGCGTGAGTGAAGAAGGTTTTCGGATCGTAAAACTCTGTTGCCAGGGAA
GAATGGTTGGGAGAGTAACTGCTCTTGACATGACGGTACCTGAGAAGAAAGCCCCGGCTA
ACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTGTCCGGAATTATTGGGC
GTAAAGCGCGCGCAGGCGGTGATTTAAGTCTGGTGTATAACCCAAGGGCTCAACTCTTGG
TGGCATTGGAAACTGGATGACTGGAGTGTAGGAGAGGAAAGTGGAATTCCACGTGTAGCG
GTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAAGGCGACTTTCTGGCCTATAA
CTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACG
Fo
CCGTAAACGATGAATGCTAGGTGTTAGGGGTTTCAATACCCTTGGTGCCGAAGTTAACAC
ATTAAGCATTCCGCCTGGGGAGTACGCTCGCAAGAGTGAAACTCAAAGGAATTGACGGGG
rP
ACCCGCACAAGCAGTGGAGTATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGG
TCTTGACATCCTCTTGAATACATTAGAGATAGTGTAGGCTTTCGGGACAAGAGAGACAGG
ee
TGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCG
CAACCCTTGATCTTAGTTGCCA
>295-37-HRB2
rR
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGACAACGTTTCGA
ev
AAGGAACGCTAATACCGCATACGTCCTACGGGAGAAAGTGGGGGACCTTCGGGCCTCACG
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CTATCAGATGAGCCTAGGCCGGATTAGCTAGTTGGTGAGGTAAAGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AGCGAATACCTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATCCAA
AACTGGCAAGCTAGAGTACGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACATCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
Page 96 of 160
Page 97 of 160
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-38-HRB2
AGCGGCGAACGGGTGAGTAATGCTTCGGAATCTACCCAGTAGTGGGGAATAACCAATCGA
Fo
AAGGTTGGCTAATACCGCATACGTCCTACGGGAGAAAGCGGGGGATCGTAAGACCTCGCG
CTATCGGATGAGCCGAAGCCGGATTAGCTAGTTGGTAGGGTAATGGCCTACCAAGGCGAC
rP
GATCCGTAGCTGGTCTGAGAGGACGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGGGAAACCCTGATCCAGCGACGC
ee
CGCGTGTGTGAAGAAGGCCTGCGGGTTGTAAAGCACTTTTAGTGGGGATGAAAAGTGCAG
AGCTAACACCTCTGCATCTTGACCTAACCCACAGAAAAAGCACCGGCTAACTCTGTGCCA
rR
GCAGCCGCGGTAATACAGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGTGC
GTAGACGTTAATGTAAGTCGGGTGTGAAAGCCCCGGGCTCAACCTGGGAATTGCATTCGA
ev
GACTGCATTGCTAGGGTGCGGAAGAGGGAAGCGGAATTTCCGGTGTAGCGGTGAAATGCG
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Applied Microbiology and Biotechnology
TAGATATCGGAAGGAACACCAGTGGCGAAAGCGGCTTCCTGGTCCGACACCGACGTTCAG
GCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCATAAACGAT
GAGAACTAGACGTTGAGGGGGGTAAAGCCTCTCAGTGTCGTAGCTAACGCGCTAAGTTTC
TCCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGGAACTGACGGGGGACCCGCAC
AAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAAGAACCTTACCTGGTCTTGACA
TCCTGGGAATCCTGCAGAAATGCGGGAGTGCCGCAAGGAACCCAGAGACAGGTGCTGCAT
GGCTGTCGTCAGCTCGTGTCGTAAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTT
GTCCTTAGTTGCCA
>295-39-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGACAACGTTTCGA
Applied Microbiology and Biotechnology
AAGGAACGCTAATACCGCATACGTCCTACGGGAGAAAGTGGGGGACCTTCGGGCCTCACG
CTATCAGATGAGCCTAGGCCGGATTAGCTAGTTGGTGAGGTAAAGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGTCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AGCGAATACCTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTTAATCGGAATTACTGGGCGTAAAGCGCG
CGTAGGTGGTTTGTTAAGTTGAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATCCA
Fo
AAACTGGCAAGCTAGAGTACGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGC
GTAGATATAGGAAGGAACATCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGA
rP
GGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGA
TGTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGAC
ee
CGCCTGGGAAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAG
CGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCC
rR
AATGAACTTTCCAGAGATGGATTGGTGCCTCCGGGAACATTGAGACAGGTGCTGCATGGC
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTC
CTTAGTTACCA
iew
>295-4-HRB2
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AGCGGCGGACGGGTGAGTAACACGTAGGTAACCTGCCACTCAGACTGGGATAACTACCGG
AAACGGTAGCTAAGACCGGATACGCTTAAAGGAGGGCATCCTCTTTTAAGGAAAAGCGGA
GCAATCTGCTGCTGAATGATGGACCTGCGGCGCATTAGCTAGTTGGTGAGGTAGCGGCTC
ACCAAGGCGACGATGCGTAGCCGACCTGAGAGGGTGAACGGCCACACTGGGACTGAGACA
CGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATCTTCGGCAATGGACGGAAGTCTGA
CCGAGCAACGCCGCGTGAGTGAAGAAGGTTTTCGGATCGTAAAACTCTGTTGCCAGGGAA
GAATGGTTGGGAGAGTAACTGCTCTTGACATGACGGTACCTGAGAAGAAAGCCCCGGCTA
ACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTGTCCGGAATTATTGGGC
GTAAAGCGCGCGCAGGCGGTGATTTAAGTCTGGTGTATAACCCAAGGGCTCAACTCTTGG
Page 98 of 160
Page 99 of 160
TGGCATTGGAAACTGGATGACTGGAGTGTAGGAGAGGAAAGTGGAATTCCACGTGTAGCG
GTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTTTCTGGCCTATAAC
TGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGC
CGTAAACGATGAATGCTAGGTGTTAGGGGTTTCAATACCCTTGGTGCCGAAGTTAACACA
TTAAGCATTCCGCCTGGGGAGTACGCTCGCAAGAGTGAAACTCAAAGGAATTGACGGGGA
CCCGCACAAGCAGTGGAGTATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGT
CTTGACATCCTCTTGAATACATTAGAGATAGTGTAGGCTTTCGGGACAAGAGAGACAGGT
GGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGC
Fo
AACCCTTGATCTTAGTTGCCA
>295-40-HRB2
rP
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
ee
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
rR
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTCTGGCAGGGACGATGATGACGGTACCTGCAGAAT
ev
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
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Applied Microbiology and Biotechnology
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGGCTAGAGTGAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
ATAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
Applied Microbiology and Biotechnology
>295-42-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGGATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCCTTGC
GCTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGA
CGATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATG
CCGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGT
AAATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCC
Fo
AGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCG
CGTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCA
rP
AAACTGACGAGCTAGAGTATGGCAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGC
GTAGATATAGGGAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGA
ee
GGTGCGAAAGCGTGGGGAGCAAACAGGATTAGGTACCCTGGTAGTCCACGCCGTAAACGA
TGTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGAC
rR
CGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAG
CGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCC
ev
AATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGC
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TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTC
CTTAGTTACCA
>295-45-HRB2
AGCGGCAGACGGGAGAGTAACACGTGGGAACGTGCCCTTCAGTTCAGAACAACCCAGGGA
AACTTGGGCTAATACCGGATACGTCCGAAAGGAGAAAGATTTATCGCTGAAGGATCGGCC
CGCGTCTGATTAGCTAGTTGGTGAGGTAACGGCTCACCAAGGCGACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCTCACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGGATGATGA
AGGCCCTAGGGTTGTAAAGTCCTTTCGGCGGGGAAGATAATGACGGTACCCGCAGAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
Page 100 of 160
Page 101 of 160
ATCACTGGGCGTAAAGCGCACGTAGGGCGGCTTTTTAAGTCAGGGGTGAAATCCTGGAGC
TCAACTCCAGAACTGCCTTTGATACTGAGAAGCTTGAGTCCGGGAGAGGTGAGTGGAACT
GCGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCA
CTGGCCCGGTACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCT
GGTAGTCCACGCTGTAAACGATGGATGCTAGCCGTTGTCGGGTTTACTCGTCAGTGGCGC
AGCTAACGCATTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAA
TTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGAAGCAACGCGCAGAAC
CTTACCAGCTCTTGACATGTCCCGTATGAGTACCAGAGATGGAACTCTTCAGTTCGGCTG
Fo
GCGGGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCCTTAGTTGCCA
>295-46-HRB2
rP
AGTGGCGAACGGGTGAGTAATACATCGGAACGTGCCCTGTAGTGGGGGGATAACTAGTCG
ee
AAAGACTAGCTAATACCGCATACGACCTAAGGGTGAAAGTGGGGGACCGCAAGGCCTCAT
GCTATAGGAGCGGCCGATGTCTGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGA
rR
CGATCAGTAGCTGGTCTGAGAGGACGATCAGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATTTTGGACAGTGGGGGCAACCCTGATCCAGCAATG
ev
CCGCGTGTGTGAAGAAGGCCTTCGGGTTGTAAAGCACTTTTGTCCGGGAAGAAATCGCAC
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Applied Microbiology and Biotechnology
CTGATAATACCGGGTGTGGATGACGGTACCGGAAGAATAAGGACCGGCTAACTACGTGCC
AGCAGCCGCGGTAATACGTAGGGTCCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGTG
CGCAGGCGGTTGTGCAAGACCGATGTGAAATCCCCGGGCTTAACCTGGGAATTGCATTGG
TGACTGCACGGCTAGAGTGTGTCAGAGGGGGGTAGAATTCCACGTGTAGCAGTGAAATGC
GTAGAGATGTGGAGGAATACCGATGGCGAAGGCAGCCCCCTGGGATAACACTGACGCTCA
TGCACGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCCTAAACGA
TGTCAACTAGTTGTTGGGGGATTCATTTTCCTTAGTAACGTAGCTAACGCGTGAAGTTGA
CCGCCTGGGGAATACGGTCGCAAGATTAAAACTCAAAGGAATTGACGGGGACCCGCACAA
GCGGTGGATGATGTGGATTAATTCGATGCAACGCGAAAAACCTTACCTACCCTTGACATG
CCACTAACGAAGCAGAGATGCATTAGGTGCTCGAAAGAGAAAGTGGACACAGGTGCTGCA
Applied Microbiology and Biotechnology
TGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCT
TGTCTCTAGTTGCTA
>295-47-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAATCTGCCCTTAGCTTCGGGATAGCTCCGGG
AAACCGGAATTAATACCGGATATGACTATGGCCGACATCAGCCATGGTGGAAAGTTTTTC
GGCTAGGGATGAGCTCGCGGCCTATCAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCGA
CGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGAAAGCCTGACGCAGCGACG
Fo
CCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAAAG
TGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGTA
rP
GGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGGCGGTCTGCCACGT
CCGCTGTGAAAACCTAGGGCTTAACCCTGGGCCTGCAGTAGATACGGGCAGACTAGAGGT
ee
AGGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
CCGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAG
rR
CAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGTTAGGTGTGGGGT
CCTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
ev
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
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AATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGA
TATGGTGTCCGTAAGGGCCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCTATGTTGCCA
>295-5-HRB2
AGTGGCGCACGGGTGAGTAACACGTGACTAACCTACCTTTTAGTGGGGGATAACCTAGGG
AAACCTGGGCTAATACCGCATAACACTTACGAGTCAAAGCAGCAATGCGCTGAAAGAGGG
GGTCGCGGCCGATTAGCTAGTTGGCGGGGTAATAGCCCACCAAGGCAATGATCGGTATCC
GGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
CAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGGA
TGAAGTCCCTTGGGACGTAAACTCCTTTCGATCGGGACGATAATGACGGTACCGGAAGAA
Page 102 of 160
Page 103 of 160
GAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATGCGAGGGGGGCAAGCGTTGTTC
GGAATTATTGGGCGTAAAGGGTGCGTAGGTGGTTCGGCAAGTCTTGTGTGAAATCTTCAG
GCTCAACTTGAAGTCTGCACAAGAAACTGCCGGGCTTGAGTATGGGAGAGGTGAGTGGAA
TTTCCGGTGTAGCGGTGAAATGCGTAGATATCGGAAGGAAACACCTGTGGCGAAAGCGGC
TCACTGGACCATTACTGACACTGAGGCACGAAAGCTAGGGGAGCAAACAGGATTAGATAC
CCTGGTAGTCCTAGCCCTAAACGATGATCGCTTGGTGTGGCGGGTATCCAACCCTGCCGT
GCCGAAGCTAACGCGTTAAGCGATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAA
AGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGA
Fo
AGAACCTTACCTGGGCTCGAAATGTAGTGGACTGGGGTAGGAATATCCCTTCCTAGCAAT
AGGTCGCTATATAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAA
rP
GTCCCGCAACGAGCGCAACCCTTATCTCCAGTTGCCA
>295-62-HRB2
ee
AGTGGCGAACGGGTGAGTAACACGTGAGTAACCTGCCCTTGACTTTGGGATAACTTCAGG
AAACTGGGGCTAATACCGGATAGGAGCTCCTGCTGCATGGTGGGGGTTGGAAAGTTTCGG
rR
CGGTTGGGGATGGACTCGCGGCTTATCAGCTTGTTGGTGGGGTAGTGGCTTACCAAGGCT
TTGACGGGTAGCCGGCCTGAGAGGGTGACCGGCCACATTGGGACTGAGATACGGCCCAGA
ev
CTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGGAAGCCTGATGCAGCAAC
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Applied Microbiology and Biotechnology
GCCGCGTGCGGGATGACGGCCTTCGGGTTGTAAACCGCTTTCGCCTGTGACGAAGCGTGA
GTGACGGTAATGGGTAAAGAAGCACCGGCTAACTACGTGCCAGCAGCCGCGGTGATACGT
AGGGTGCGAGCGTTGTCCGGATTTATTGGGCGTAAAGGGCTCGTAGGTGGTTGATCGCGT
CGGAAGTGTAATCTTGGGGCTTAACCCTGAGCGTGCTTTCGATACGGGTTGACTTGAGGA
AAGGTAGGGGAGAATGGAATTCCTGGTGGAGCGGTGGAATGCGCAGATATCAGGAGGAAC
ACCAGTGGCGAAGGCGGTTCTCTGGGCCTTTCCTGACGCTGAGGAGCGAAAGCGTGGGGA
GCGAACAGGCTTAGATACCCTGGTAGTCCACGCTGTAAACGGTGGGTACTAGGTGTGGGG
TCCATTCCACGGGTTCCGTGCCGTAGCTAACGCTTTAAGTACCCCGCCTGGGGAGTACGG
CCGCAAGGCTAAAACTCAAAGGAATTGACGGGGCCCCGCACAAGCGGCGGAGCATGCGGA
TTAATTCGATGCAACGCGTAGAACCTTACCTGGGTTTGACATGGATCGGGAGTGCTCAGA
Applied Microbiology and Biotechnology
GATGGGTGTGCCTCTTTTGGGGTCGGTTCACAGGTGGTGCATGGCTGTCGTCAGCTCGTG
TCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTTCACTGTTGCCA
>295-64-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
Fo
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
rP
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
ee
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
rR
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
ev
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
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GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATGGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-66-HRB2
AGTGGCGCACGGGTGCGTAACGCGTGGGAATCTACCCTTGGGTTCGGAATAACAGTTAGA
AATGACTGCTAATACCGGATGATGACGAAAGTCCAAAGATTTATCGCCCAGGGATGAGCC
CGCGTAGGATTAGGTAGTTGGTGGGGTAAAGGCCTACCAAGCCGACGATCCTTAGCTGGT
CTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGAGTGATGA
Page 104 of 160
Page 105 of 160
AGGCCTTAGGGTTGTAAAGCTCTTTTACCAGGGATGATAATGACAGTACCTGGAGAATAA
GCTCCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGAGCTAGCGTTGTTCGGA
ATTACTGGGCGTAAAGCGCACGTAGGCGGCTATTCAAGTCAGAGGTGAAAGCCCAGGGCT
CAACCCTGGAACTGCCTTTGAAACTAGGTAGCTAGAATTCTGGAGAGGTCAGTGGAATTC
CGAGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTGAC
TGGACAGATATTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGATAACTAGTTGTTCGGGCACTTGGTGCTTGAGTGACGC
AGCTAACGCATTAAGTTATCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAA
Fo
TTGACGGGGGCCTGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAAC
CTTACCAGCGTTTGACATCCTTGGACGACTACCAGAGATGGTTTTCTTCCCTTCGGGGAC
rP
CAAGTGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCC
CGCAACGAGCGCAACCCTCGTCCTTAGTTGCCA
>295-69-HRB2
ee
AGTGGCGACCGGGTGAGTAACACGTGACTAACCTACCCTCGAGTGTGGAATAACATCGGG
rR
AAACCGATGCTAATACCGCATAACATCGGCGCTTTTAAGAGATGCCGATCAAAGGAGTTA
TCCGCTTGAGGAGGGGGTCGCGGCTGATTAGCTAGTTGGCGGGGTAACGGCCCACCAAGG
ev
CGAAGATCGGTAGCCGGCCTGAGAGGGCGCACGGCCACACTGGAACTGAAACACGGTCCA
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Applied Microbiology and Biotechnology
GACTCCTACGGGAGGCAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCA
ACGCCGCGTGGAGGATGAAGCCCCTTGGGGCGTAAACTCCTTTCGACCAAGACGATAATG
ACGGTACTGGTGGAAGAAGCACCGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGG
GTGCAAGCGTTGTTCGGAATTATTGGGCGTAAAGGGTGCGTAGGCGGCGCGGTAAGTCAC
CTGTGAAATCTCCAAGCTTAACTTGGAGCCTGCAGGCGAAACTGCCGTGCTGGAGTATGG
AGAGGTGCGTGGAATTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTG
TGGCGAAAGCGGCGCACTGGACCATAACTGACGCTGATGCACGAAAGCTAGGGGAGCAAA
CAGGATTAGATACCCTGGTAGTCCTAGCCCTAAACGACGATTGCTTGGTGTGGTGGGTAC
CCAATCCCACTGTGCCGTAGCTAACGCGATAAGCAATCCGCCTGGGGAGTACGGTCGCAA
GGCTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATT
Applied Microbiology and Biotechnology
CGACGCAACGCGAAGAACCTTACCTGGGCTCGAAATGTAGTGGAATCGGGTGGAAACATC
CGCGTCTCGCAAGAGACTGCTATATAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATCCCTAGTTGCCA
>295-71-HRB2
AGTGGCGAACGGGTGAGTAACACATGAGCAACCTGCCCCGAAGACTGGGACAACACCGGG
AAACCGGTGCTAATACCGGATATCCCTATCGGACCGCATGCTCTGATAAGGAAATGGATT
CCGCTTCGGGAGGGGCTCGTGGCCTATCAGCTAGTTGGTGAGGTAATAGCTCACCAAGGC
ATCGACGGGTAGCTGGTCTGAGAGGACGATCAGCCACACTGGGACTGAGACACGGCCCAG
Fo
ACTCCTACGGGAGGCAGCAGTGGGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCAA
CGCCGCGTGGAGGACGAAGGCTTTCTGAGTTGTAAACTCCTTTCAGCAGGGACGATAGTG
rP
ACGGTACCTGCAGAAGAAGCACCGGCCAACTACGTGCCAGCAGCCGCGGTGATACGTAGG
GTGCAAGCGTTGTCCGGATTTATTGGGCGTAAAGAGCTCGTAGGCGGTTTGATAAGTCGG
ee
GTGTGAAACCTCCAGGCTCAACCTGGAGCCGCCACTCGATACTGTCATGACTAGAATCCG
GTAGGGGACCACGGAATTCCTGGTGTAGCGGTGAAATGCGCAGATATCAGGAGGAACACC
rR
AGCAGCGAAGGCGGTGGTCTGGGCCGAAATTGACGCTGAGGAGCGAAAGCGTGGGGAGCG
AACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCACTAGGTGTGGGGACT
ev
ATTCAACGGTTTCCGTGCCGCAGCTAACGCATTAAGTGCCCCGCCTGGGGAGTACGGCCG
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CAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTGGCTTA
ATTCGAGGCAACGCGAAGAACCTTACCTGGGTTTGACATGTAGGGAAAAGCCGTAGAGAT
ACGGTGTCCTTCGGGGCCTTACACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGGG
ATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTCCTATGTTGCCA
>295-75-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGACAACGTTTCGA
AAGGAACGCTAATACCGCATACGTCCTACGGGAGAAAGTGGGGGACCTTCGGGCCTCACG
CTATTAGATGAGCCTAGGCCGGATTAGCTAGTTGGTGAGGTAAAGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
Page 106 of 160
Page 107 of 160
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AGCGAATACCTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATCCAA
AACTGGCAAGCTAGAGTACGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACATCAGTGGCGAAGGCGACCACCTGGACTGTTACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
Fo
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
rP
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
rR
>295-79-HRB2
ee
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
ev
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
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Applied Microbiology and Biotechnology
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGCCTAGAGTGAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACGCCGCCTAGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
Applied Microbiology and Biotechnology
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
>295-80-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
Fo
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
rP
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTGATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
ee
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
rR
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
ev
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
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GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTTAGTGGCGCAGCTAACGCATTAAGTTGAC
CGCCTGGGGAGTACGGCCGCAAGGTTAAAAACTCAAATGAATTGACGGGGGCCCGCACAA
GCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATC
CAATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGT
CCTTAGTTACCA
>295-81-HRB2
AGTGGCGCACGGGTGAGTAGCGCGTGAGAACCTGCCCTGGAGTGGGGGATAACCGAGGGA
AACTTCGGCTAATACCGCATACGCCGGTAGTCTTGCAAGAGATCGCCGGGAAAGATTGAT
CGCTCTAGGAGGGGCCCGCGTCGGATTAGCTTGTTGGTGGGGTAACGGCCCACCAAGGCT
Page 108 of 160
Page 109 of 160
TTGATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGATTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAAT
GCCGCGTGAGTGATGAAGGCCTTCGGGTTGTAAAGCTCTTTCGCCCGCGACGATGATGAC
GGTAGCGGGAGAAGAAGCCCCGGCTAACTTCTTGCCAGCAGCCGCGGTAATACGAAGGGG
GCAGAGCGTTGTTCGGATTTACTGGGCGTAAAGGGCGCGTAGGCGGCGCTGGAAGTCAGG
CGTGAAAGCCCCGGGCTCAACCTGGGAATGGCGCTTGGGACTCTGGTGCTGGAGTTCGGG
AGAGGAGCGTGGAATTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGG
TGGCGAAGGCGGCGCTCTGGACCGAGACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAA
Fo
CAGGATTAGATACCCTGGTAGTCCACGCGGTAAACGATGTGTGCTAGACGTTGGGGGGCC
TAGCTCTCCGGTGTCGCCGCTAACGCTGTAAGCACACCGCCTGGGGAGTACGGCCGCAAG
rP
GTTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTC
GACGCAACGCGAAGAACCTTACCAGCCCTTGACATGCCTCGTATGGGGGCGAGAGATCGC
ee
CTTCTTGGGTTCGGCCGGCGGGGACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGT
GAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCATCTGCAGTTGCCA
>295-83-HRB2
rR
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
ev
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
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Applied Microbiology and Biotechnology
CTATCAGATGAGCCTGGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCTAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTCGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
Applied Microbiology and Biotechnology
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTCCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-87-HRB2
AGTGGCAGACGGGTGAGTAACGCGTGGGAACATACCCTCCGGTTCGGAATAGCTCAGGGA
Fo
AACTTGGATTAATACCGGATACGGCAGTCAAGAGCGATCTTGGAGGCGAAAGATTGATCG
CCGGAGGATTGGCCCGCGTTCGATTAGCTTGTTGGTGAGGTAACGGCTCACCAAGGCGAC
rP
GATCGATAGCTGGTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGC
ee
CGCGTGAGTGATGACGGCCTTAGGGTTGTAAAGCTCTTTCGCTCGGGACGATAATGACGG
TACCGAGAGAAGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGC
rR
TAGCGTTGTTCGGAATTACTGGGCGTAAAGCGCGTGTAGGCGGGTGTCTAAGTCAGGGGT
GAAATGCCAGGGCTCAACCTTGGAACTGCCTTTGATACTGGAGATCTTGAGTCCGGGAGA
ev
GGTGAGTGGAATTGCGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGG
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CGAAGGCGGCTCACTGGCCCGGAACTGACGCTGAGACGCGAAAGCGTGGGGAGCAAACGG
GATTAGATACCCTGGTAGTCCACGCTGTAAACGATGGATGCTAGCCGTTGGGGAGCTTGC
TCTTCAGTGGCGCAGCTAACGCTTTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTA
AAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAG
CAACGCGCAGAACCTTACCAGCTTTTGACATGTCCTGGACGGATTGCAGAGATGCGATCT
TCCCTTCGGGGCCGGGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATG
TTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGCCCTTAGTTGCCA
>295-89-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAACCTGCCCTTAGCTTTGGGATAGCTCCGGG
AAACCGGAATTAATACCGAGTATTACGTCAATCGACATCGGCTGACGTGGAAAGATTTAT
Page 110 of 160
Page 111 of 160
CGGCTGAGGATGGACTCGCGGCCTATCAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGAC
GCCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAAA
GTGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGT
AGGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGACTGTCACGT
CTGCTGTGAAAAGCTAGGGCTTAACCCTGGCCTTGCAGTGGATACGGGCAGACTAGAGGT
AGGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
Fo
CCGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAG
CGAACAGGATTAGATACCCTGGTAGTCCACGCTTTAAACGTTGGGCGCTAGGTGTGGGAT
rP
CCTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
ee
AATTCGACGCAGCGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGA
TACGGTGTCCGTAAGGGTCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
rR
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTTCTATGTTGCCA
>295-91-HRB2
ev
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
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Applied Microbiology and Biotechnology
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
Applied Microbiology and Biotechnology
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACAGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>295-93-HRB2
Fo
AGTGGCGCACGGGGTGAGTAACACGTGACTAACCTACCTTTTAGTGGGGGATAACCTAGG
GAAACCTGGGCTAATACCGCATAATACTTACGAGTCAAAGCAGCAATGCGCTGAAAGAGG
rP
GGGTCGCGGTCGATTAGTTAGTTGACAGGGTAATGGCCTACCAAGACTGTGATCGATATC
CGGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAG
ee
GCAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGG
ATGAAGTCCCTTGGGACGTAAACTCCTTTCGATCGGGACGATAATGACGGTACCGGAAGA
rR
AGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCAAGCGTTGTT
CGGAATTATTGGGCGTAAAGGGTGCGTAGGTGGTTCGGCAAGTCTTGTGTGAAATCTTCA
ev
GGCTCAACTTGAAGTCTGCACAAGAAACTGCCGGGCTTGAGTATGGGAGAGGTGAGTGGA
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ATTTCCGGTGTAGCGGTGAAATGCGTAGATATCGGAAGGAACACCTGTGGCGAAAGCGGC
TCACTGGACCATTACTGACACTGAGGCACGAAAGCTAGGGGAGCAAACAGGATTAGATAC
CCTGGTAGTCCTAGCCCTAAACGATGATCGCTTGGTGTGGCGGGTATCCAACCCTGCCGT
GCCGCAGCTAACGCGTTAAGCGATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAA
AGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGA
AGAACCTTACCTGGGCTCGAAATGTAGTGGACTGGGGTAGAAATATCCCTTCCTAGCAAT
AGGCTGCTATATAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAA
GTCCCGCAACGAGCGCAACCCTTATCTCCAGTTGCCA
>295-94-HRB2
AGTGGCAGACGGGTGAGTAACGCGTGGGAACATACCCTCCGGTTCGGAATAGCTCAGGGA
Page 112 of 160
Page 113 of 160
AACTTGGATTAATACCGGATACGGCTGAGAGGCGAAAGATTTATCGCCGGAGGATTGGCC
CGCGTTCGATTAGCTTGTTGGTGAGGTAACGGCTCACCAAGGCGATGATCGATAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
CGGCCTTAGGGTTGTAAAGCTCTTTCGCTCGGGACGATAATGACGGTACCGAGATAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGA
ATTACTGGGCGTAAAGCGCGTGTAGGCGGGTCTTTAAGTCAGGGGTGAAATGCCAAGGCT
CAACCTTGGAACTGCCTTTGATACTGGAGATCTTGAGTCCGGGAGAGGTGAGTGGAATTG
Fo
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCCCGGAACTGACGCTGAGACGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
rP
GTAGTCCACGCTGTAAACGATGGATGCTAGCCGTTGGGGAGCTTGCTCTTCAGTGGCGCA
GCTAACGCTTTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
ee
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
TTACCAGCTTTTGACATGTCCTGGACGGATTGCAGAGATGCGATCTTCTCTTCGGAGCCG
rR
GGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCC
GCAACGAGCGCAACCCTCGCCCTTAGTTGCCA
>295-95-HRB2
iew
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Applied Microbiology and Biotechnology
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
Applied Microbiology and Biotechnology
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>318-101-HRB2-3
Fo
AKTGGCGGACGGTGAGTAACACGTGGGAACGTGCCCTTGGTTCGGAACAACTCAGGGAAW
rP
CTTGAGCTAATACCGGATGTGCCCTTCGGGGGAAAGATTTATCGCCATTGGAGCGGCCCG
CGTTGGATTAGCTAGTTGGTGGGGTAAAGGCCCACCAAGGCTACGATCCATAGCTGGTCT
ee
GAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAGCA
GTTAGGAATCCTGCGCAATGGGCGAAAGCCTGACGCAGCCATGCCGCGTGAATGATGAAG
rR
GTCTTAGGATTGTAAAATTCTTTCAGCGGGGACGATAATGACGGTACCCGCAGAAGAAGC
TCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGAAT
ev
TACTGGGCGTAAAGGGCGCGTAGGCGGATGTTTAAGTCAGAGGTGAAAGCCCAGGGCTCA
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ACCTTGGAAATGCCTTTGATACTGGACATCTTGAGTATGGGAGAGGTGAGTGGAACTCCG
AGTGTAGAGGTGAAATTCGTAGATATTCGGAAGAACACCAGTGGCGAAGGCGACTCACTG
GCCCATTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGT
AGTCCACGCTGTAAACGATGAGTGCTAGTTGTCGGCATGCATGCATGTCGGTGACGCAGC
TAACGCATTAAGCACTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAATTG
ACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACCTT
ACCACCTTTTGACATGCCTGGACCGCCGGAGAGATCCGGTTTTCCCTTCGGGGACTAGGA
CACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAA
CGAGCGCAACCCTCGCCATTAGTTGCCA
>319-183-HRB2
Page 114 of 160
Page 115 of 160
AGTGGCGTACGGGTGAGTAACACGTGACTAACCTACCCTCGAGTGGGGAATAACCTCGGG
AAACCGGGGCTAATACCGCATAACATCTACGGATCAAATGCGTAAGCAGCTTGAGGAGGG
GGTCGCGGCCGATTAGCTAGTTGGCGGGGTAATGGCCCACCAAGGCAATGATCGGTAGCC
GGCCTGAGAGGGCGCACGGCCACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
CAGCAGTGGGGAATTTTGCGTAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGGA
TGAAGCCCCTTGGGGTGTAAACTCCTCTCGATCGGGACGATTATGACGGTACCGGATGAA
GAAGCACCGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTGTTC
GGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTGCGGTAAGTCTGTTGTGAAATCTCCGG
Fo
GCTCAACTCGGAGTCTGCAACGGAAACTGCCGTGCTCGAGTATGGGAGAGGTGAGTGGAA
TTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTGTGGCGAAAGCGGCT
rP
CACTGGACCATTACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATACC
CTGGTAGTCCTAGCCCTAAACTATGATCGCTTGGTGTGACAGGTACCCAATCCTGTCGTG
ee
CCGGAGCTAACGCGTTAAGCGATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAA
GGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGACGCAACGCGAA
rR
GAACCTTACCTGGGCTCGAAGCGTAGTGGACTGAGGTAGAAATATCTTTTTCCCGCAA
>319-188-HRB2
ev
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCTGGGGTGGGGGACAACAGCGGGA
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Applied Microbiology and Biotechnology
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGACGGTCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGGGCAATCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGTTGTTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTAGCGACTAGAGTAAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
Applied Microbiology and Biotechnology
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGGACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGCAGGCCTGGCACAGAGATGTGTCTTTCCCGCAAGGGA
CCTGCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTTGCCTTTAGTTGCCA
>319-191-HRB2
AGCGGCGCACGGGTGAGTAACACGTGACGAACCTACCCTCGAGTGGGGAATAACCTGGGG
Fo
AAACCCGGGCTAATACCGCATAACACCTACGGGTCAAAGGAGCAATCCGCTTGAGGAGGG
GGTCGCGGCAGATTAGTTAGTTGGCGGGGTAATGGCCCACCAAGACGATGATCTGTATCC
rP
GGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
CAGCAGTGGGGAATTTTGCGCAATGGGGGAAGCCCTGACGCAGCAACGCCGCGTGGAGGA
ee
TGAAGTCCCTTGGGACGTAAACTCCTTTCGACCGGGACGATGATGACGGTACCGGATGAA
GAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCGAGCGTTGTTC
rR
GGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTTCCGCAAGTCTTATGTGAAATCTTCGG
GCTCAACTCGAAGCCTGCATAGGAAACTACGGGGCTTGAGTGTGGGAGAGGTGAGTGGAA
ev
TTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTGTGGCGAAAGCGGCT
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CACTGGACCATAACTGACGCTGATGCACGAAAGCTGGGGGAGCAAACAGGATTAGATACC
CTGGTAGTCCCAGCCCTAAACCATGATTGCTTGGTGTGACGGGTACCCAATCCCGCCGTG
CCGCAGCTAACGCGATAAGCAATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAA
GGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGAA
GAACCTTACCTGGGCTCGAAATGTTGTGGACCGGGGTAGAAATATCCCTTCCCCGCAAGG
GGCCGCAATATAGGTGCCGCATGGCTGTCGTCAGCTCGTGTCATGAGATGTTGGGTTAAG
TCCCGCACGAGCGCAACCCTTATCTCCAGTTGCTA
>319-195-HRB2-2
AGTGGCGCACGGGTGAGTAACACGTGACTAACCTACCCTTGAGTGGGGGATAACCTAGGG
AAACCTGGGCTAATACCGCATAATACCTACGGGTCAAAGGAGCAATTCGCTTAAGCGAGG
Page 116 of 160
Page 117 of 160
GGGTCGCGGCCGATTAGTTAGTTGGCGGGGTAATGGCCCACCAAGACGATGATCGGTATC
CGGCCTGAGAGGGCGCACGGACACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAG
GCAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGG
ATGAAGTCCCTTGGGACGTAAACTCCTTTCGACCGGGACGATAATGACGGTACCGGAAGA
AGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAGGGGGGCGAGCGTTGTT
CGGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTTTGGTAAGTCTTGTGTGAAATCTTCG
GGCTCAACTCGAAGTCTGCACGAGAAACTGCCGGGCTTGAGTGTGGGAGAGGTGAGTGGA
ATTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTGTGGCGAAAGCGGC
Fo
TCACTGGACCACAACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATAC
CCTGGTAGTCCTAGCCCTAAACGATGATCGCTTGGTGTGACGGGTACCCAATCCCGCCGT
rP
GCCGAAGCTAACGCGTTAAGCGATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAA
AGGAATTGACGGGGGCCCGCACAGGCGGTGGAGCATGTGGTTTAATTCGACGCAACGCGA
ee
AGAACCTTACCTGGGCTCGAAATGAGGTGGACCGGAGTAGAAATATTCCTTCCCCGCAAG
GGGCCGCTTTATAGGTGCTGCATGGCTG
>325-101-HRB2
rR
AGCGGCCGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
ev
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
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Applied Microbiology and Biotechnology
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCCAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
Applied Microbiology and Biotechnology
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAA
>325-102-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGACAACGTTTCGA
AAGGAACGCTAATACCGCATACGTCCTACGGGAGAAAGTGGGGGACCTTCGGGCCTCACG
Fo
CTATCAGATGAGCCTAGGCCGGATTAGCTAGTTGGTGAGGTAAAGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
rP
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
ee
AGCGAATACCTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
rR
GTAGGTGGTTTGTTAAGTTGAATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATCCAA
AACTGGCAAGCTAGAGTACGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
ev
TAGATATAGGAAGGAACATCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
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GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>325-104-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
Page 118 of 160
Page 119 of 160
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGGCTAGAGTGAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
Fo
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
rP
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCATAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ee
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
ev
>325-106-HRB2
rR
AGTGGCGAACGGGTGAGTAGCACGTGAGCAACCTGCCCCGAAGACTGGGACAACACCGGG
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Applied Microbiology and Biotechnology
AAACCGGTGCTAATACCGGATATCCCCACCGAGTCGCATGGCTTGGTGAGGAAATGTTTT
TCGCTTCGGGAGGGGCTCGCGGCCTATCAGCTTGTTGGTGAGGTAACGGCTCACCAAGGC
TTCGACGGGTAGCTGGTCTGAGAGGACGATCAGCCACACTGGGACTGAGACACGGCCCAG
ACTCCTACGGGAGGCAGCAGTGGGGAATCTTGCACAATGGGCGAAAGCCTGATGCAGCAA
CGCCGCGTGAGGGACGAAGGCTTTCTGAGTTGTAAACCTCTTTCAGCAGGGACGATTGTG
ACGGTACCTGCAGAAGAAGCCCCGGCCAACTACGTGCCAGCAGCCGCGGTAATACGTAGG
GGGCAAGCGTTGTCCGGATTTATTGGGCGTAAAGAGCTCGTAGGCGGCTTGGCAGGTCGG
ATGTGAAACCTCCAGGCTCAACCTGGAGTCGCCATTCGATACTGCCATGGCTAGAGTTTG
GTAGGGGACCACGGAATTCCTGGTGTAGCGGTGAAATGCGCAGATATCAGGAGGAACACC
AGCGGCGAAGGCGGTGGTCTGGGCCAATACTGACGCTGAGGAGCGAAAGCGTGGGGAGCG
Applied Microbiology and Biotechnology
AACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCACTAGGTGTGGGGACC
TATCGACGGTTTCTGTGCCGCAGCTAACGCATTAAGTGCCCCGCCTGGGGAGTACGGCCG
CAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTGGCTTA
ATTCGATGCAACGCGAAGAACCTTACCTGGGTTTGACATTTAGGGAAAAGCCGTAGAGAT
ACGGTGTCCTTCGGGGTCCTAAACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAG
ATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATTCTATGTTGCCA
>325-107-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
Fo
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
rP
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
ee
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
rR
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGGCTAGAGTGAGGAAGAGGGTTGTGGAAT
ev
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
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CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCATAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCCTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
>325-109-HRB2
AGTGGCAGACGGGTGAGTAACGCGTGGGAACATACCCTCCGGTTCGGAATAGCTCAGGGA
AACTTGGATTAATACCGGATACGGCTGAGAGGCGAAAGATTTATCGCCGGAGGATTGGCC
Page 120 of 160
Page 121 of 160
CGCGTTCGATTAGCTTGTTGGTGAGGTAACGGCTCACCAAGGCGATGATCGATAGCTGGT
CTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAG
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGAGTGATGA
CGGCCTTAGGGTTGTAAAGCTCTTTCGCTCGGGACGATAATGACGGTACCGAGATAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGGAGGGGGCTAGCGTTGTTCGGA
ATTACTGGGCGTAAAGCGCGTGTAGGCGGGTCTTTAAGTCAGGGGTGAAATGCCAAGGCT
CAACCTTGGAACTGCCTTTGATACTGGAGATCTTGAGTCCGGGAGAGGTGAGTGGAATTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
Fo
TGGCCCGGAACTGACGCTGAGACGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCTGTAAACGATGGATGCTAGCCGTTGGGGAGCTTGCTCTTCAGTGGCGCA
rP
GCTAACGCTTTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGAACC
ee
TTACCAGCTTTTGACATGTCCTGGACGGATTGCAGAGATGCGATCTTCTCTTCGGAGCCG
GGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCC
GCAACGAGCGCAACCCTCGCCCTTAGTTGCCA
ev
>325-110-HRB2
rR
AGCGGCGAACGGGTGAGTAACACGTGAGGAACCTGCCCCTGGCTCTGGGATAGCTCCGGG
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Applied Microbiology and Biotechnology
AAACCGGGATTAATACCGGATATGACCACTTGATGCATGTCTTGTGGTGGAAAGTTTTTC
GGCTGGGGATGGCCTCGCGGCCTATCAGCTTGTTGGTGGGGTGATGGCCTACCAAGGCGA
CGACGGGTAGCCGGCCTGAGAGGGCAACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGGAAGCCTGACGCAGCGACG
CCGCGTGGGGGATGACGGCCTTCGGGTTGTAAACCTCTTTCAGCAGGGACGAAGCTAACG
TGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGTA
GGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGCCTGTTGCGTC
TGCTGTGAAATCCCGGGGCTTAACCCCGGGCTTGCAGTGGATACGGGCAGGCTAGAGGCA
GGCAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACAC
CGGTGGCGAAGGCGGTTCTCTGGGCCTGTACTGACGCTGAGGAGCGAAAGCGTGGGGAGC
Applied Microbiology and Biotechnology
GAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGGTC
CTTCCACGGACTCTGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCCG
CAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTTA
ATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATACAGGGAAAAGCCGCAGAGAT
GTGGTGTCCGTAAGGGTCCTGTACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAG
ATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCTATGTTGCCA
>325-111-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
Fo
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
rP
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
ee
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
rR
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGGCTAGAGTGAGGAAGAGGGTTGTGGAAT
ev
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
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CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCATAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
>325-113-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCTGGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
Page 122 of 160
Page 123 of 160
CCTGCGTCTGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGACGATCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGTTGTTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTAGCGACTAGAGTAAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
Fo
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGGACTTAGTTTCTCAGTGTC
rP
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ee
ACCTTACCAGGATTTGACATGGGCAGGCCTGGCACAGAGATGTGTCTTTCCCGCAAGGGA
CCTGCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTTGCCTTTAGTTGCCA
ev
>325-115-HRB2
rR
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
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Applied Microbiology and Biotechnology
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
Applied Microbiology and Biotechnology
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCGTAACGAGCGCAACCCTTGTCCT
TAGTTACCA
>325-117-HRB2
Fo
AGTGGCGCACGGGTGAGTAGCGCGTGGGAACCTGCCCTGGAGTGGGGGATAACCGAGGGA
AACTTCGGCTAATACCGCATACGCCGGTGGTCTCGAGAGAGACGGCCGGGAAAGATTTAT
rP
CGCTCTAGGAGGGGCCCGCGTCGGATTAGGTAGTTGGTGGGGTAACGGCCTACCAAGCCT
GTGATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGA
ee
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAAT
GCCGCGTGAGTGATGAAGGCCTTCGGGTTGTAAAGCTCTTTCGCACGCGAGGATGATGAC
rR
GGTAGCGTGAGAAGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGG
GCGAGCGTTGTTCGGATTTACTGGGCGTAAAGGGCGCGTAGGCGGTGCTTCAAGTCAGGC
ev
GTGAAAGCCCCGGGCTCAACCTGGGAACGGCGCTTGGGACTGGGGCACTGGAGTTCGGGA
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GAGGAGCGTGGAATTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGT
GGCGAAGGCGGCGCTCTGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCGGTAAACGATGTGTGCTAGACGTTGGGGGGCCT
AGCTCCCCGGTGTCGCCGCTAACGCTTTAAGCACACCGCCTGGGGAGTACGGCCGCAAGG
TTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCG
ACGCAACGCGAAGAACCTTACCAGCCCTTGACATGCCTCGTATGGGGCCGAGAGATCGGC
TTCTTCGGTTCGGCCGGCGGGGACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTG
AGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCATCCTCAGTTGCCA
>325-118-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAACCTGCCCTTAGCTTTGGGATAGCTCCGGG
Page 124 of 160
Page 125 of 160
AAACCGGAATTAATACCGAATATTACGTCAATCGACATCGGCTGACGTGGAAAGATTTAT
CGGCTGAGGATGGACTCGCGGCCTATCAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCG
ACGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGAC
GCCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAAA
GTGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGT
AGGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGACTGTCACGT
CTGCTGTGAAAAGCTAGGGCTTAACCCTGGCCTTGCAGTGGATACGGGCAGACTAGAGGT
Fo
AGGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACA
CCGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAG
rP
CGAACAGGACTAGATACCCTGGTAGTCCACGCTGTAAACGTTGGGCGCTAGGTGTGGGAT
CCTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCC
ee
GCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTT
AATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGA
rR
TACGGTGTCCGTAAGGGTCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGA
GATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTTCTATGTTGCCA
>325-119-HRB2
iew
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Applied Microbiology and Biotechnology
AGTGGCGAACGGGTGAGTAGCACGTGAGCAACCTGCCCCGAAGACTGGGACAACACCGGG
AAACCGGTGCTAATACCGGATATCCCCACCGAGTCGCATGGCTTGGTGAGGAAATGTTTT
TCGCTTCGGGAGGGGCTCGCGGCCTATCAGCTTGTTGGTGAGGTAACGGCTCACCAAGGC
TTCGACGGGTAGCTGGTCTGAGAGGACGATCAGCCACACTGGGACTGAGACACGGCCCAG
ACTCCTACGGGAGGCAGCAGTGGGGAATCTTGCACAATGGGCGAAAGCCTGATGCAGCAA
CGCCGCGTGAGGGACGAAGGCTTTCTGAGTTGTAAACCTCTTTCAGCAGGGACGATTGTG
ACGGTACCTGCAGAAGAAGCCCCGGCCAACTACGTGCCAGCAGCCGCGGTAATACGTAGG
GGGCAAGCGTTGTCCGGATTTATTGGGCGTAAAGAGCTCGTAGGCGGCTTGGCAGGTCGG
ATGTGAAACCTCCAGGCTCAACCTGGAGTCGCCATTCGATACTGCCATGGCTAGAGTTTG
GTAGGGGACCACGGAATTCCTGGTGTAGCGGTGAAATGCGCAGATATCAGGAGGAACACC
Applied Microbiology and Biotechnology
AGCGGCGAAGGCGGTGGTCTGGGCCAATACTGACGCTGAGGAGCGAAAGCGTGGGGAGCG
AACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCACTAGGTGTGGGGACC
TATCGACGGTTTCTGTGCCGCAGCTAACGCATTAAGTGCCCCGCCTGGGGAGTACGGCCG
CAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTGGCTTA
ATTCGATGCAACGCGAAGAACCTTACCTGGGTTTGACATTTAGGGAAAAGCCGTAGAGAT
ACGGTGTCCTTCGGGGTCCTAAACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAG
ATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATTCTATGTTGCCA
>325-120-HRB2
Fo
AGTGGCGGACGGGGTGAGTAACGCGTAGGTATCTATCCCTGGGTGGGGGACAACCGTGGG
AAACTACGGCTAATACCGCATGACACCTGAGGGTCAAAGGCGCAAGTCGCCTGGGGAGGA
rP
GCCTGCGTCCGATTAGCTTGTTGGTGGGGTAAAAGCCTACCAAGGCGACGATCGGTAGCT
GGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGG
ee
CAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGGGTGA
AGAAGGTCTTCGGATTGTAAAGCCCTTTCGGCGGGGACGATGATGACGGTACCCGCAGAA
rR
GAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTC
GGAATGACTGGGCGTAAAGGGCGCGTAGGCGGTTCATAGAGTCGGGCGTGAAATTCCTGG
ev
GCTTAACCTGGGGGCTGCGTTCGATACCTATGGACTGGAGTGAGGAAGAGGGTCGTGGAA
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TTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCAGTGGCGTAGGCGGCG
ACCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACC
CTGGTAGTCCACGCCGTAAACGATGTGCGCTGGATGTTGGGCGGCCTAGCCGCTCAGTGT
CGTAGCTAACGCGGTAAGCGCACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAG
GAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGAAGCAACGCGCAG
AACCTTACCAGGGCTTGACATGGGGAGGCCGTGTCCGGAAACGGGCATTTCCCGCAAGGG
ACCTCCCACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAG
TCCCGCAACGAGCGCAACCCTCGCCTTCAGTTGCCA
>325-121-HRB2
AGCGGCGAACGGGTGAGTAACGCGTGAGAATTTACCCTTTAGTGAAGAATACCCCCGAGA
Page 126 of 160
Page 127 of 160
AATCGGGGCTAATACTGCATACGTCCTACGGGAGAAAGATGGCCTCTTTGCTATCGCTAA
AGGCTAAGCTTGCGTACTATCAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTATGACG
GTTAACCGGCCTGAGAGGGTGTTCGGTCACACTGGAACTTAGACACGGTCCAGACTCCTA
CGGGAGGCAGCAGTGAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGACGCCGCG
TGGAGGATGAAGGTCTTAGGATTGTAAACTTCTGTTAAGTGGGAAGAAAGATCCATTTCT
AATAAAGATGGATTATGACGGTACCATTAGAGAAAGCACCGGCTAAACTCGTGCCAGCAG
CCGCGGTAATACGAGTGGTGCAAGCGTTATTCGGATTTATTGGGTGTAAAGGGTGCGCAG
ACGGTTTATTAAGTCACTTGTTAAATTCTCTGGCTTAACTAGAGGCAAGCGGGCGAAACT
Fo
GATGAACTAGAGGGTGGAAGAGAGAAGTGGAATTCTCGGAGTAGCGGTAAAATGCGTAGA
TCTCGAGAGGAACACCAATGGCGAAGGCAGCTTCTTGGTCCATTTCTGACGTTCAGGCAC
rP
GAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGATC
ACTAGACGTTAGTTCTGTTACAGAATTAGTGTCGTAGCTAACGCGTTAAGTGATCCACCT
ee
GGGGACTACGGTCGCAAGACTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTG
GAACATGTGGTTTAATTCGACACTACGCGAGAAACCTTACCTAGGCTTGACATGCTTTTG
rR
ACCGTTGTGGAAACACAACTTTTTAGGCTTCGGTCTAAACAATTGCACAGGTGCTGCATG
GCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCTCTAACGAGCGCACCCCTGC
TGTCAGTTGCTA
iew
>325-122-HRB2
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Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCTGGGGTGGGGGACAACAGTGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTTGTTGGTGGGGTAAAGGCTTACCAAGGCGACGATCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAAGCTAGAGTGAGGAAGAGGGTTGTGGAAT
Applied Microbiology and Biotechnology
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCACGAGCGCAACCCTCGCCTTT
>325-123-HRB2
Fo
AGCGGCGAACGGGTGAGTAACGCGTGAGAATTTACCCTTTAGTGAAGAATACCCCCGAGA
rP
AATCGGGGCTAATACTGCATACGTCCTACGGGAGAAAGATGGCCTCTTTGCTATCGCTAA
AGGCTAAGCTTGCGTACTATCAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTATGACG
ee
GTTAACCGGCCTGAGAGGGTGTTCGGTCACACTGGAACTTAGACACGGTCCAGACTCCTA
CGGGAGGCAGCAGTGAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGACGCCGCG
rR
TGGAGGATGAAGGTCTTAGGATTGTAAACTTCTGTTAAGTGGGAAGAAAGATCCATTTCT
AATAAAGATGGATTATGACGGTACCATTAGAGAAAGCACCGGCTAAACTCGTGCCAGCAG
ev
CCGCGGTAATACGAGTGGTGCAAGCGTTATTCGGATTTATTGGGTGTAAAGGGTGCGCAG
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ACGGTTTATTAAGTCACTTGTTAAATTCTCTGGCTTAACTAGAGGCAAGCGGGCGAAACT
GATGAACTAGAGGGTGGAAGAGAGAAGTGGAATTCTCGGAGTAGCGGTAAAATGCGTAGA
TCTCGAGAGGAACACCAATGGCGAAGGCAGCTTCTTGGTCCATTTCTGACGTTCAGGCAC
GAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGATC
ACTAGACGTTAGTTCTGTTACAGAATTAGTGTCGTAGCTAACGCGTTAAGTGATCCACCT
GGGGACTACGGTCGCAAGACTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTG
GAACATGTGGTTTAATTCGACACTACGCGAGAAACCTTACCTAGGCTTGACATGCTTTTG
ACCGTTGTGGAAACACAACTTTTTAGGCTTCGGTCTAAACAATTGCACAGGTGCTGCATG
GCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCTCTAACGAGCGCAACCCCTG
CTGTCAGTTGCTA
Page 128 of 160
Page 129 of 160
>325-124-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
Fo
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
rP
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
ee
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGCTGACC
rR
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ev
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCGTAACGAGC
>325-125-HRB2
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Applied Microbiology and Biotechnology
AGCGGCGGACGTGTGAGTAATGCCTAGGAATCTGCCTGGTAGGGGGGGATAACGTTCGGA
AACGGGCGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCCAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
Applied Microbiology and Biotechnology
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
Fo
GTCGTCGGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGC
>325-126-HRB2
rP
AGTGGCGTACGGGTGAGTAACACGTGACTAACCTACCCTCGAGTGGGGAATAACCTCGGG
AAACCGGGGCTAATACCGCATAACATCTACGGATCAAATGCGTAAGCAGCTTGAGGAGGG
ee
GGTCGCGGCCGATTAGCTAGTTGGCGGGGTAATGGCCCACCAAGGCAATGATCGGTAGCC
GGCCTGAGAGGGCGCACGGCCACACTGGAACTGAAACACGGTCCAGACTCCTACGGGAGG
rR
CAGCAGTGGGGAATTTTGCGCAATGGGGGAAACCCTGACGCAGCAACGCCGCGTGGAGGA
TGAAGCCCCTTGGGGTGTAAACTCCTTTCGATCGGGACGATTATGACGGTACCGGATGAA
ev
GAAGCACCGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTGTTC
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GGAATTATTGGGCGTAAAGGGTGCGTAGGCGGTGCGGTAAGTCTGTTGTGAAATCTCCGG
GCTCAACTCGGAGTCTGCAACGGAAACTGCCGTGCTCGAGTATGGGAGAGGTGAGTGGAA
TTCCCGGTGTAGCGGTGAAATGCGTAGATATCGGGAGGAACACCTGTGGCGAAAGCGGCT
CACTGGACCATTACTGACGCTGATGCACGAAAGCTAGGGGAGCAAACAGGATTAGATACT
CTGGTAGTCCTAGCCCTAAACTATGATCGCTTGGTGTGACAGGTACCCAATCCTGTCGTG
CCGGAGCTAACGCGTTAAGCGATCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTCAAA
GGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGACGCAACGCGAA
GAACCTTACCTGGGCTCGAAGCGTAGTGGACTGAGGTAGAAATATCTTTTTCCCGCAAGG
GACTGCTACGTAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAG
TCCCGCACGAGCGCAACCCTTATTGCCAGTTGCCA
Page 130 of 160
Page 131 of 160
>325-127-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAATCTGCCCTTAGCTTCGGGATAGCTCCGGG
AAACCGGAATTAATACCGGATATGACCACGGCCGACATCAGCCATGGTGGAAAGTTTTTC
GGCTAGGGATGAGCTCGCGGCCTATCAGCTAGTTGGTGGGGTAACGGCCTACCAAGGCGA
CGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGCGAAAGCCTGACGCAGCGACG
CCGCGTGGGGGATGAAGGCCTTCGGGTTGTAAACCCCTTTCAGCAGGGACGAAGCGAAAG
TGACGGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAACACGTA
Fo
GGGCGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGTCTGCCACGTC
CGCTGTGAAAACCTAGGGCTTAACCCTGGGCTTGCAGTAGATACGGGCAGACTAGAGGTA
rP
GGTAGGGGAGAATGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACAC
CGGTGGCGAAGGCGGTTCTCTGGGCCTTACCTGACGCTGAGGAGCGAAAGCGTGGGGAGC
ee
AAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGGTC
CTTCCACGGATTCCGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCCG
rR
CAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTTA
ATTCGACGCAACGCGAAGAACCTTACCAAGGTTTGACATGCAGGGAAAAGCCGTAGAGAT
ev
ATGGTGTCCGTAAGGGTCCTGCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAG
ATGTTGGGTTAAGTCCGCAACGAGCGCAACCCTCGTCCTATGTTGCC
>325-128-HRB2
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Applied Microbiology and Biotechnology
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
Applied Microbiology and Biotechnology
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCTTTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
Fo
GTCGTCAGCTCGTGTCGCGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>325-129-HRB2
rP
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
ee
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTTGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCTAC
rR
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
ev
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
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GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGGGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
Page 132 of 160
Page 133 of 160
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTACGAGCGCAACCCTTGTCCT
TAGTTACCA
>325-130-HRB2
AGCGGCGAACGGGTGAGTAACGCGTGAGAATTTACCCTTTAGTGAAGAAATACCCCCGAG
AAATCGGGGCTAATACTGCATACGTCCTACGGGAGAAAGATGGCCTCTTTGCTATCGCTA
AAGGCTAAGCTTGCGTACTATCAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTATGAC
GGTTAACCGGCCTGAGAGGGTGTTCGGTCACACTGGAACTTAGACACGGTCCAGACTCCT
ACGGGAGGCAGCAGTGAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGACGCCGC
Fo
GTGGAGGATGAAGGTCTTAGGATTGTAAACTTCTGTTAAGTGGGAAGAAAGATCCATTTC
TAATAAAGATGGATTATGACGGTACCATTAGAGAAAGCACCGGCTAAACTCGTGCCAGCA
rP
GCCGCGGTAATACGAGTGGTGCAAGCGTTATTCGGATTTATTGGGTGTAAAGGGTGCGCA
GACGGTTTATTAAGTCACTTGTTAAATTCTCTGGCTTAACTAGAGGCAAGCGGGCGAAAC
ee
TGATGAACTAGAGGGTGGAAGAGAGAAGTGGAATTCTCGGAGTAGCGGTAAAATGCGTAG
ATCTCGAGAGGAACACCAATGGCGAAGGCAGCTTCTTGGTCCATTTCTGACGTTCAGGCA
rR
CGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGAT
CACTAGACGTTAGTTCTGTTACAGAATTAGTGTCGTAGCTAACGCGTTAAGTGATCCACC
ev
TGGGGACTACGGTCGCAAGACTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGT
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Applied Microbiology and Biotechnology
GGAACATGTGGTTTAATTCGACACTACGCGAGAAACCTTACCTAGGCTTGACATGCTTTT
>325-131-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCTGGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGACGGTCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGGGCAATCCTGATCCAGCAATGCCGCGTGTGTGAA
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
Applied Microbiology and Biotechnology
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGTTGTTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTAGCGACTAGAGTAAGGAAGAGGGTTGTGGAAT
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGGACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCAAAGG
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
ACCTTACCAGGATTTGACATGGGCAGGCCTGGCACAGAGATGTGTCTTTCCCGCAAGGGA
Fo
CCTGCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTTGCCTTTAGTTGCCA
>325-132-HRB2
rP
AGTGGCGAACGGGTGAGTAACACGTGAGCAACCTGCCCTTGGCTCTGGGATAGCCTCCGG
ee
AAACGGGGATTAATACCGGACATGACCTTCTCCTGCATGGGGGAGGGTGGAAAGTTTTTC
GGCCAGGGAGGGGCTCGCGGCCTATCAGCTTGTTGGGGGGGTAACGGCCCACCAAGGCGA
rR
CGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACG
ev
CCGCGTGCGGGATGAAGGCCTTCGGGTTGTAAACCGCTTTCAGCAGGGGCGAATTCAGAC
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GGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGC
GCAAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGCCTGTTGCGTCCGCT
GTGAAATCCCAGGGCTTAACCCTGGGCCTGCAGTGGATACGGGCAGGCTAGAGGCAGGCA
GGGGAGAACGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACACCGGT
GGCGAAGGCGGTTCTCTGGGCCTGTTCTGACGCTGAGGAGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGTCCCTTC
CACGGGGTCTGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCCGCAAG
GCTAAAACTCAAAGAAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTTAATTC
GACGCAACGCGAAGAACCTTACCAAGGTTTGACATGGACCGAAAACTCATGGAGACATGG
GGTCCTTCGGGGCGGTTCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGT
Page 134 of 160
Page 135 of 160
TGGGTTAAGTCCGCAACGAGCGCAACCCTCGTCCAATGTTGCCA
>325-133-HRB2
AGCGGCGAACGGGTGAGTAACGCGTGAGAATTTACCCTTTAGTGAAGAATACCCCCGAGA
AATCGGGGCTAATACTGCATACGTCCTACGGGAGAAAGATGGCCTCTTTGCTATCGCTAA
AGGCTAAGCTTGCGTACTATCAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTATGACG
GTTAACCGGCCTGAGAGGGTGTTCGGTCACACTGGAACTTAGACACGGTCCAGACTCCTA
CGGGAGGCAGCAGTGAGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCGACGCCGCG
TGGAGGATGAAGGTCTTAGGATTGTAAACTTCTGTTAAGTGGGAAGAAAGATCCATTTCT
Fo
AATAAAGATGGATTATGACGGTACCATTAGAGAAAGCACCGGCTAAACTCGTGCCAGCAG
CCGCGGTAATACGAGTGGTGCAAGCGTTATTCGGATTTATTGGGTGTAAAGGGTGCGCAG
rP
ACGGTTTATTAAGTCACTTGTTAAATTCTCTGGCTTAACTAGAGGCAAGCGGGCGAAACT
GATGAACTAGAGGGTGGAAGAGAGAAGTGGAATTCTCGGAGTAGCGGTAAAATGCGTAGA
ee
TCTCGAGAGGAACACCAATGGCGAAGGCAGCTTCTTGGTCCATTTTTGACGTTCAGGCAC
GAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGATC
rR
ACTAGACGTTAGTTCTGTTACAGAATTAGTGTCGTAGCTAACGCGTTAAGTGATCCACCT
GGGGACTACGGTCGCAAGACTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTG
ev
GAACATGTGGTTTAATTCGACACTACGCGAGAAACCTTACCTAGGCTTGACATGCTTTTG
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Applied Microbiology and Biotechnology
ACCGTTGTGGAAACACAACTTTTTAGGCTTCGGTCTAAACAATTGCACAGGTGCTGCATG
GCTGTCGTCAGCTCGTGTCGT
>325-134-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
Applied Microbiology and Biotechnology
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
Fo
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTA
ee
>325-135-HRB2
rP
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
rR
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
ev
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
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CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGCTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
Page 136 of 160
Page 137 of 160
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCGTAACGAGCGCAACCCTTGTCCT
TAGTTACCA
>325-138-HRB2
AGCGGCGAACGGGTGAGTAACACGTGAGCAACCTGCCCTTGGCTCTGGGATAGCCTCCGG
AAACGGGGATTAATACCGGACATGACCTTCTCCTGCATGGGGGAGGGTGGAAAGTTTTTC
GGCCAGGGAGGGGCTCGCGGCCTATCAGCTTGTTGGGGGGGTAACGGCCCACCAAGGCGA
CGACGGGTAGCCGGCCTGAGAGGGCGACCGGCCACACTGGGACTGAGACACGGCCCAGAC
Fo
TCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACG
CCGCGTGCGGGATGAAGGCCTTCGGGTTGTAAACCGCTTTCAGCAGGGGCGAATTCAGAC
rP
GGTACCTGCAGAAGAAGCGCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGC
GCGAGCGTTGTCCGGAATTATTGGGCGTAAAGAGCTCGTAGGCGGCCTGTTGCGTCCGCT
ee
GTGAAATCCCAGGGCTTAACCCTGGGCGTGCAGTGGATACGGGCAGGCTAGAGGCAGGCA
GGGGAGAACGGAATTCCCGGTGTAGCGGTGAAATGCGCAGATATCGGGAGGAACACCGGT
rR
GGCGAAGGCGGTTCTCTGGGCCTGTTCTGACGCTGAGGAGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCCGTAAACGTTGGGCGCTAGGTGTGGGTCCCTTC
ev
CACGGGGTCTGTGCCGCAGCTAACGCATTAAGCGCCCCGCCTGGGGAGTACGGCCGCAAG
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Applied Microbiology and Biotechnology
GCTAAAACTCAAAGAAATTGACGGGGGCCCGCACAAGCGGCGGAGCATGTTGCTTAATTC
GACGCAACGCGAAGAACCTTACCAAGGTTTGACATGGACCGAAAACTCATGGAGACATGG
GGTCCTTCGGGGCGGTTCACAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGT
TGGGTTAAGTCCCGCAACGAGCGCAACCCTCGTCCAATGTTGCC
>325-140-HRB2
AGTGGCGAACGGGTGAGTATCACGTGAGCAACCTGCCCCGAAGATTGGGATAACACCGGG
AAACCGGTGCTAATACCGAATACCCTCCACACATCGCATGATGAGTAGAGGAAATGTTTT
TTCGCTTCGGGAGGGGCTCGCGGTCCATCAGCTTGTTGGCGGGGTAATGGCCCACCAAGG
CAACGACGGATAGCTGGTCTGAGAGGACGATCAGCCGCACTGGAACTGAGACACGGTCCA
GACTCCTACGGGAGGCAGCAGTGGGGAATCTTGCGCAATGGACGAAAGTCTGACGCAGCA
Applied Microbiology and Biotechnology
ACGCCGCGTGAGGGACGAAGGCTTTCTGAGTTGTAAACCTCTTTCGACAGGAACGATTGT
GACGGTACCTGTAGAAGAAGCACCGGCCAACTATGTGCCAGCAGCCGCGGTGATACATAG
GGTGCAAGCGTTATTCGGATTTATTGGGCGTAAAGAGCTCGTAGGCGGTTCAATAAGTCA
CGTGTTAATCCCCCAGGCTCAACCTGGGGCCGCCACGTGAAACTGTTGTGACTAGAGTTT
GGTAGGGGATCACGGAATTCCTGGTGTAGCGGTGGAATGCGCAGATATCAGGAGGAACAC
CAGTAGCGAAGGCGGTGATCTGGGCCAATACTGACGCTGAGGAGCGAAAGCGTGGGGAGC
GAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGGTGGGCACTAGGTGTGGGGAC
TTTTCAACGGTTTCCGCGCCGCAGCTAACGCATTAAGTGCCCCGCCTGGGGAGTACGGTC
Fo
GCAAGACTAAAACTCAAAGAAATTGACGGGGGCCCGCACAAGCAGCGGAGCATGTGGCTT
AATTCGATGCAACGCGAAAAACCTTACCTAGATTTGACATGCTGGGAAAAGCCACAGAGA
rP
TGTGGTGTCCTTCGGGGCCCAGCACAGGTGGTGCATGGCTGTCGCCAG
>325-145-HRB2
ee
AGCGGCAGACGGGAGAGTAACACGTGGGAACGTACCCTTCAGTCCGGAACAACCCAGGGA
AACTTGGGCTAATACCGGATACGTCCGTAAGGAGAAAGATTTATCGCTGAAGGATCGGCC
rR
CGCGTCTGATTAGCTTGTTGGTGAGGTAACGGCTCACCAAGGCTACGATCAGTAGCTGGT
CTGAGAGGATGATCAGCCTCACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAG
ev
CAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGGGTGATGA
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AGGCCCTAGGGTTGTAAAGCCCTTTCGGCGGGGAAGATAATGACGGTACCCGCAGAAGAA
GCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCGGA
ATCACTGGGCGTAAAGCGCACGTAGGCGGCTTTTTAAGTCAGGGGTGAAATCCTGGAGCT
CAACTCCAGAACTGCCTTTGATACTGAGGAGCTTGAGTCCGGGAGAGGTGAGTGGAACTG
CGAGTGTAGAGGTGAAATTCGTAGATATTCGCAAGAACACCAGTGGCGAAGGCGGCTCAC
TGGCCCGGTACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTG
GTAGTCCACGCCGTAAACGATGGATGCTAGCCGTTGTCGGGTTTACTCGTCAGTGGCGCA
GCTAACGCATTAAGCATCCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAAT
TGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTCAATTCGAAGCAACGCGCAGAACC
TTATCAGCCCTTGACATGTCCCGTATGAGTACCAGAGATGGAACTCTTCAGTTCGGCTGG
Page 138 of 160
Page 139 of 160
CGGGAACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTC
CCGCAACGAGCGCAACCCTCGCCCTTAGTTGCCA
>325-146-HRB2
AGTGGCGGACGGGTGAGTAACACGTAGGAATCTATCCCAGGGTGGGGGACAACAGCGGGA
AACTGCTGCTAATACCGCATGATACCTGAGGGTCAAAGGCGCAAGTCGCCTTGGGAGGAG
CCTGCGTCTGATTAGCTTGTTGGTGAGGTAAAGGCTCACCAAGGCTACGATCAGTAGCTG
GTCTGAGAGGATGATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGC
AGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCAATGCCGCGTGTGTGAA
Fo
GAAGGTCTTCGGATTGTAAAGCACTTTTGGCAGGGACGATGATGACGGTACCTGCAGAAT
AAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGCTCG
rP
GAATGACTGGGCGTAAAGGGCGCGTAGGCGGCATGTACAGTCAGAAGTGAAATTCCTGGG
CTCAACCTGGGGACTGCTTTTGATACGTGCAGGCTAGAGTGAGGAAGAGGGTTGTGGAAT
ee
TTCCAGTGTAGAGGTGAAATTCGTAGATATTGGAAAGAACACCGGTGGCGAAGGCGGCAA
CCTGGTCCTTTACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCC
rR
TGGTAGTCCACGCTGTAAACGATGTGTGCTGGATGTTGGGGAACTTAGTTTCTCAGTGTC
GTAGCTAACGCGATAAGCACACCGCCTGGGGAGTACGGCCGCAAGGTTGAAACTCATAGG
ev
AATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGCAGA
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Applied Microbiology and Biotechnology
ACCTTACCAGGATTTGACATGGGGAGGACCGGTACAGAGATGTACTTTTCCCGCAAGGGA
CCTTCCGCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGCCTTTAGTTGCCA
>325-147-HRB2
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
Applied Microbiology and Biotechnology
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
Fo
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
rP
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCT
TA
>325-148-HRB2
ee
AGTGGCGCACGGGTGAGTAGCGCGTGGGAACCTGCCCTGGAGTGGGGGATAACCGAGGGA
rR
AACTTCGGCTAATACCGCATACGCCGGTGGTCTCGAGAGAGACGGCCGGGAAAGATTTAT
CGCTCTAGGAGGGGCCCGCGTCGGATTAGGTAGTTGGTGGGGTAACGGCCTACCAAGCCT
ev
GTGATCCGTAGCTGGTCTGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGA
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CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCAAT
GCCGCGTGAGTGATGAAGGCCTTCGGGTTGTAAAGCTCTTTCGCACGCGAGGATGATGAC
GGTAGCGTGAGAAGAAGCCCCGGCTAACTTCGTGCCAGCAGCCGCGGTAATACGAAGGGG
GCGAGCGTTGTTCGGATTTACTGGGCGTAAAGGGCGCGTAGGCGGTGCTTCAAGTCAGGC
GTGAAAGCCCCGGGCTCAACCTGGGAACGGCGCTTGGGACTGGGGCACTGGAGTTCGGGA
GAGGAGCGTGGAATTCCCAGTGTAGAGGTGAAATTCGTAGATATTGGGAAGAACACCGGT
GGCGAAGGCGGCGCTCTGGACCGATACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAAC
AGGATTAGATACCCTGGTAGTCCACGCGGTAAACGATGTGTGCTAGACGTTGGGGGGCCT
AGCTCCCCGGTGTCGCCGCTAACGCTTTAAGCACACCGCCTGGGGAGTACGGCCGCAAGG
TTAAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCG
Page 140 of 160
Page 141 of 160
ACGCAACGCGAAGAACCTTACCAGCCCTTGACATGCCTCGTATGGGGCCGAGAGATCGGC
TTCTTCGGTTCGGCCGGCGGGGACACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTG
AGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCATCCTCAGTTGCCA
From HRB3:
>294-30-HRB3
Fo
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
rP
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGGAA
ee
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCAT
GCCGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTG
rR
TAGATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGC
CAGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGC
ev
GCGTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTC
AAAACTGACTGACTAGAGTATGGTAGAGGATGGTGGAATTTCCTGTGTAGCGGTGAAATG
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Applied Microbiology and Biotechnology
CGTAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTG
AGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACG
ATGTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGA
CCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAA
GCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATC
CAATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGG
CTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGT
CCTTAGTTACCA
>294-31-HRB3
Applied Microbiology and Biotechnology
AGTGGCGGACGGGTGAGTAACGCGTAAGAACCTGCCCTTGGGAGGGGAACAGCAGCTGGA
AACGGCTGCTAATACCCCGTAGGCTGAGGAGCAAAAGGAGGAATCCGCCCGAGGAGGGGC
TCGCGTCTGATTAGCTAGTTGGTGAGGCAATAGCTTACCAAGGCGATGATCAGTAGCTGG
TCCGAGAGGATGATCAGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCA
GCAGTGGGGAATTTTCCGCAATGGGCGAAAGCCTGACGGAGCAATGCCGCGTGGAGGTAG
AAGGCCTACGGGTCCTGAACTTCTTTTCCCAGAGAAGAAGCAATGACGGTATCTGGGGAA
TAAGCATCGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGATGCAAGCGTTATCC
GGAATGATTGGGCGTAAAGCGTCTGTAGGTGGCTTTTTAAGTCCGCCGTCAAATCCCAGG
Fo
GCTCAACCCTGGACAGGCGGTGGAAACTACCAAGCTTGAGTACGGTAGGGGCAGAGGGAA
TTTCCGGTGGAGCGGTGAAATGCGTAGAGATCGGAAAGAACACCAACGGCGAAAGCACTC
rP
TGCTGGGCCGACACTGACGCTGAGAGACGAAAGCTAGGGGAGCGAATGGGATTAGATACC
CCAGTAGTCCTAGCCGTAAACGATGGATACTAGGCGCTGTGCATATCGACCCGTGCAGTG
ee
CTGTAGCTAACGCGTTAAGTATCCCGCCTGGGGAGTACGTTCGCAAGAATGAAACTCAAA
GGAATTGACGGGGGCCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGATGCAAAGCGAA
rR
GAACCTTACCAGGGCTTGACATGCCGCGAATCCTCTTGAAAGAGAGGGGTGCCTTCGGGA
ACGCGGACACAGGTGGTGCATGGCTGTCGTCAGCTCGTGCCGTAAGGTGTTGGGTTAAGT
CCCGCAACGAGCGCAACCCTCGTGTTTAGTTGCCA
iew
>294-4-HRB3
ev
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AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
Page 142 of 160
Page 143 of 160
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAAAGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCCTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAGGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-57-HRB3
rP
Fo
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
ee
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
rR
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
ev
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
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Applied Microbiology and Biotechnology
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAACCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCGACCCTTGTCC
Applied Microbiology and Biotechnology
TTAGTTACCA
>294-62-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGAGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
Fo
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
rP
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
ee
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
rR
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
ev
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
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ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-71-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAAGGCG
ACGATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGA
CTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCAT
GCCGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAG
Page 144 of 160
Page 145 of 160
TAAATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGC
CAGCAGCCGCGGGTAATACAAAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCG
CGCGTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATT
CAAAACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAAT
GCGTAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACT
GAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAAC
GATGTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTG
ACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACA
Fo
AGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACAT
CCAATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATG
rP
GCTGTCGTCAGCTCGTGTCGTGAGATGTTGTGTTAAGTCCCGTAACGAGCGCAACCCTTG
TCCTTAGTTACCA
>294-72-HRB3
ee
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
rR
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGGTCACCAAGGCGAC
ev
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
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Applied Microbiology and Biotechnology
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAAGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
Applied Microbiology and Biotechnology
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-79-HRB3
ACCGGCGCACGGGTGAGTAACGCGTATCCAACCTGCCCCCAACTAGGGAATAACCTTGCG
AAAGTAAGACTAATACCCTATAATTTCCTCAGATGTCATCTGACGAGGAATAAAGATTTA
TCGGTTGTGGATGGGGATGCGTCTGATTAGCTTGTTGGCGGGGTAACGGCCCACCAAGGC
Fo
AACGATCAGTAGGGGTTCTGAGAGGAAGGTCCCCCACATTGGAACTGAGACACGGTCCAA
ACTCCTACGGGAGGCAGCAGTGAGGAATATTGGTCAATGGGCGGAAGCCTGAACCAGCCA
rP
AGTAGCGTGCAGGATGACGGCCCTATGGGTTGTAAACTGCTTTTATACAGGAATAAAGTT
AGCCACGTGTGGTTATTTGTAGGTACTGTATGAATAAGGACCGGCTAATTCCGTGCCAGC
ee
AGCCGCGGTAATACGGAAGGTCCAGGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT
AGGCCGTCTGTTAAGCGTGTTGTGAAATGTAGATGCTCAACATCTGAATTGCAGCGCGAA
rR
CTGGCAGACTTGAGTGTGCGCAACGTAGGCGGAATTCGTGGTGTAGCGGTGAAATGCTTA
GATATCACGAAGAACTCCGATTGCGAAGGCAGCTTACGGGAGCACAACTGACGCTGAAGC
ev
TCGAAAGTGCGGGTATCGAACAGGATTAGATACCCTGGTAGTCCGCACGGTAAACGATGG
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ATGCCCGCTGTTGACCCACCTGGGCCAGCGGCCAAGCGAAAGCATTAAGCATCCCACCTG
GGGAGTACGCCGGCAACGGTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGAGG
AACATGTGGTTTAATTCGATGATACGCGAGGAACCTTACCCGGGCTTGAATTGCAGAGGA
GAGATCCAGAGATGGTGATGCCCTTCGGGGCCTCTGTGAAGGTGCTGCATGGTTGTCGTC
AGCTCGTGCCGTGAGGTGTCGGCTTAAGTGCCATAACGAGCGCAACCCCCTTCTTTAGTT
GCCA
>294-89-HRB3
AGTGGCGGACGGGTGAGTAATGCTTGGGAATCTAGCTTATGGAGGGGGATAACTACGGGA
AACTGTAGCTAATACCGCGTAGAATCGAGAGATGAAAGTGTGGGACCTTCGGGCCACATG
CCATAGGATGAGCCCAAGCGGGATTAGGTAGTTGGTGAGGTAAAGGCTCACCAAGCCGAC
Page 146 of 160
Page 147 of 160
GATCTCTAGCTGGTCTGAGAGGATGACCAGCCACACTGGGACTGAGACACGGCCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGCGCAATGGGGGCAACCCTGACGCAGCCATGC
CGCGTGAATGAAGAAGGCCTTCGGGTTGTAAAGTTCTTTCGGTAGCGAGGAAGGCATTTA
GTTTAATAGACTAGGTGATTGACGTTAACTACAGAAGAAGCACCGGCTAACTCCGTGCCA
GCAGCCGCGGTAATACGGAGGGTGCGAGCGTTAATCGGAATAACTGGGCGTAAAGGGCAC
GCAGGCGGTGACTTAAGTGAGGTGTGAAAGCCCCGGGCTTAACCTGGGAATTGCATTTCA
TACTGGGTCGCTAGAGTACTTTAGGGAGGGGTAGAATTCCACGTGTAGCGGTGAAATGCG
TAGAGATGTGGAGGAATACCGAAGGCGAAGGCAGCCCCTTGGGAATGTACTGACGCTCAT
Fo
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGAT
GTCGATTTGGGGGTTGAACTTTAAGTTTGGCGCCCGTAGCTAACGTGATAAATCGACCGC
rP
CTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGG
TGGAGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTACTCTTGACATCCAGA
ee
GAACATTCCAGAGATGGATTGGTGCCTTCGGGAACTCTGAGACAGGTGCTGCATGGCTGT
CGTCAGCTCGTGTTGTGAAATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATCCTT
TGTTGCCA
ev
>294-91-HRB3
rR
GGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
iew
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Applied Microbiology and Biotechnology
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTTCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
Applied Microbiology and Biotechnology
GTGCGTAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-93-HRB3
Fo
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
rP
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
ee
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
rR
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
ev
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
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AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-94-HRB3
Page 148 of 160
Page 149 of 160
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCGCCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
Fo
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
rP
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTACCCGAT
ee
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
rR
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
ev
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>294-95-HRB3
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Applied Microbiology and Biotechnology
AGCCGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGGATAACGTTCGG
AAACGGACGCTAATACCGCATACGTCCTACGGGAGAAACCAGGGGACCTTCGGGCCTTGC
GCTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGA
CGATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGAC
TCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATG
CCGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGT
AAATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCC
AGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCG
Applied Microbiology and Biotechnology
CGTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCA
AAACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGC
GTAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGA
GGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGA
TGTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGAC
CGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAG
CGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCC
AATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGC
Fo
TGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTC
CTTAGTTACCA
>317-102-HRB3
rP
AGTGGCGGACGGGTGAGTAACATTTAGGAATCTGCCTAGTAGTGGGGGATAGCTCGGGGA
ee
AACTCGAATTAATACCGCATACGACCTACGGGTGAAAGGGGGCGCAAGCTCTTGCTATTA
GATGAGCCTAAATCAGATTAGCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGACGATCTG
rR
TAACTGGTCTGAGAGGATGATCAGTCACACCGGAACTGAGACACGGTCCGGATTCCTACG
GGAGGCAGCAGTGGGGAATATTGGACAATGGGGGCAACCCTGATCCAGCCATGCCGCGTG
ev
TGTGAAGAAGGCCTTTTGGTTGTAAAGCACTTTAAGCAGGGAGGAGAGGCTAATGGTTAA
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TACCCATTAGATTAGACGTTACCTGCAGAATAAGCACCGGCTAACTCTGTGCCAGCAGCC
GCGGTAATACAGAGGGTGCGAGCGTTAATCGGAATTACTGGGCGTAAAGCGAGTGTAGGT
GGCTCATTAAGTCACATGTGAAATCCCCGGGCTTAACCTGGGAACTGCATGTGATACTGG
TGGTGCTAGAATATGTGAGAGGGAAGTAGAATTCCAGGTGTAGCGGTGAAATGCGTAGAG
ATCTGGAGGAATACCGATGGCGAAGGCAGCTTCCTGGCATAATATTGACACTGAGATTCG
AAAGCGTGGGTAGCAAACAGGATTAGACACCCTGGTAGTCCACGCCGTAAACGATGTCTA
CTAGCCGTTGGGGTCCTTGAGACTTTAGTGGCGCAGTTAACGCGATAAGTAGACCGCCTG
GGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGGTGG
AGCATGTGGTTTAATTCGATGCAACGCGAAGAACCTTACCTGGTCTTGACATAGTGAGAA
TCCTGCAGAGATGCGGGAGTGCCTTCGGGAATTCACATACAGGTGCTGCATGGCTGTCGT
Page 150 of 160
Page 151 of 160
CAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTTTCCTTATT
TGCCA
>317-108-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
Fo
CGCGTGTGTGAAGAAGGTTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGT
AGATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTYGKCCAG
rP
MAGCCSSGGTAYWCAHAGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGTA
GGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCCTGGGAACTACATTCAAAA
ee
CTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCGTA
GATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAGGT
rR
GCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGT
CAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACCGC
ev
CTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGCGG
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Applied Microbiology and Biotechnology
TGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCAAT
GAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCTGT
CGTCAGCTCGTGTCGTGAGAATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCCT
TAGTTACCA
>317-121-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGCCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
Applied Microbiology and Biotechnology
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTTCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
Fo
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
rP
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
rR
>317-127-HRB3
ee
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
ev
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
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GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
Page 152 of 160
Page 153 of 160
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACTA
>317-128-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
Fo
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
rP
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
ee
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
rR
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTACATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
ev
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
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Applied Microbiology and Biotechnology
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>317-129-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
Applied Microbiology and Biotechnology
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
GATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
Fo
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
rP
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
ee
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
rR
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>317-149-HRB3
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AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCGCCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTCGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
Page 154 of 160
Page 155 of 160
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAGCTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>317-154-HRB3
Fo
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
rP
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
ee
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
rR
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
ev
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
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Applied Microbiology and Biotechnology
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTAGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGAAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
Applied Microbiology and Biotechnology
>317-170-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGTGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGCAGTA
AATTAATACTTTGCTGTTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
Fo
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
rP
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
ee
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
rR
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTGATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ev
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
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GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>324-101-HRB3
ACCGGCGCATGGGTGAGTAACGCGTATCCAACCTGCCCCCAACTAGGGAATAACCTTGCG
AAAGTAAGACTAATACCCTATAATTTCCTCAGATGTCATCTGACGAGGAATAAAGATTTA
TCGGTTGTGGATGGGGATGCGTCTGATTAGCTTGTTGGCGGGGTAACGGCCCACCAAGGC
AACGATCAGTAGGGGTTCTGAGAGGAAGGTCCCCCACATTGGAACTGAGACACGGTCCAA
ACTCCTACGGGAGGCAGCAGTGAGGAATATTGGTCAATGGGCGGAAGCCTGAACCAGCCA
AGTAGCGTGCAGGATGACGGCCCTATGGGTTGTAAACTGCTTTTATACAGGAATAAAGTT
AGCCACGTGTGGTTATTTGTAGGTACTGTATGAATAAGGACCGGCTAATTCCGTGCCAGC
Page 156 of 160
Page 157 of 160
AGCCGCGGTAATACGGAAGGTCCAGGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT
AGGCCGTCTGTTAAGCGTGTTGTGAAATGTAGATGCTCAACATCTGAATTGCAGCGCGAA
CTGGCAGACTTGAGTGTGCGCAACGTAGGCAGAATTCGTGGTGTAGCGGTGAAATGCTTA
GATATCACGAAGAACTCCGATTGCGAAGGCAGCTTACGGGAGCACAACTGACGCTGAAGC
TCGAAAGTGCGGGTATCGAACAGGATTAGATACCCTGGTAGTCCGCACGGTAAACGATGG
ATGCCCGCTGTTGACCCACCTGGGCCAGCGGCCAAGCGAAAGCATTAAGCATCCCACCTG
GGGAGTACGCCGGCAACGGTGAAACTCAAAGGAATTGACGGGGGCCCGCACAAGCGGAGG
AACATGTGGTTTAATTCGATGATACGCGAGGAACCTTACCCGGGCTTGAATTGCAGAGGA
Fo
AAGATCCAGAGATGGTGATGCCCTTCGGGGCCTCTGTGAGGGTGCTGCATGGTTGTCGTC
AGCTCGTGCCGTGAGGTGTCGGCTTAAGTGCCATAACGAGCGCAACCCCTTTCTTTAGTT
GCCA
ee
>324-126-HRB3
rP
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
rR
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
ev
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
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Applied Microbiology and Biotechnology
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTACATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
Applied Microbiology and Biotechnology
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>324-142-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAT
GATCCGTAACTGGTCTGAGAGGATGATCAGTCACACTGGGACTGAGACACGGTCCAGACT
Fo
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGGTCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
rP
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
ee
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTGTGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
rR
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
ev
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
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GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>324-151-HRB3
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGCCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
Page 158 of 160
Page 159 of 160
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTTGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACTGACTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTAATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTTCACGCCGTAAACGAT
Fo
GTCAACTAGCCGTTGGAAGCCTTGAGCTTTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
rP
GGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCCAGAGATGGATTGGTGCCTTCGGGAGCATTGAGACAGGTGCTGCATGGCT
ee
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
>324-156-HRB3
rR
AGCGGCGGACGGGTGAGTAATGCCTAGGAATCTGCCTGGTAGTGGGGGATAACGTTCGGA
ev
AACGGACGCTAATACCGCATACGTCCTACGGGAGAAAGCAGGGGACCTTCGGGCCTTGCG
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Applied Microbiology and Biotechnology
CTATCAGATGAGCCTAGGTCGGATTAGCTAGTTGGTGGGGTAATGGCTCACCAAGGCGAC
GATCCGTAACTGGCCTGAGAGGATGATCAGTCACACTGGAACTGAGACACGGTCCAGACT
CCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGC
CGCGTGTGTGAAGAAGGTCTTCGGATTGTAAAGCACTTTAAGTTGGGAGGAAGGGTTGTA
GATTAATACTCTGCAATTTTGACGTTACCGACAGAATAAGCACCGGCTAACTCTGTGCCA
GCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGC
GTAGGTGGTTCGTTAAGTTGGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCATTCAA
AACTGACGAGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTGTGTAGCGGTGAAATGCG
TAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAG
GTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGAT
Applied Microbiology and Biotechnology
GTCAACTAGCCGTTGGGAGCCTTGAGCTCTTAGTGGCGCAGCTAACGCATTAAGTTGACC
GCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGCACAAGC
GGTGGAGCATGTAGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGGCCTTGACATCCA
ATGAACTTTCTAGAGATAGATTGGTGCCTTCGGAAACATTGAGACAGGTGCTGCATGGCT
GTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCC
TTAGTTACCA
iew
ev
rR
ee
rP
Fo
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