Monitoring progress toward the end of the HIV epidemic in New York State: HIV Epidemiology in NYC Sarah L. Braunstein, PhD MPH Director, HIV Epidemiology and Field Services Program New York City Department of Health and Mental Hygiene HIV in NYC, 1981-2013 140,000 New AIDS Diagnoses 12,000 120,000 Reported Persons Living with HIV (non-AIDS) 10,000 100,000 HIV-Related Deaths 8,000 80,000 6,000 60,000 New HIV Diagnoses Reported Persons Living with AIDS 4,000 40,000 2,000 Number of Reported PLWHA 20,000 NYS HIV HAART CDC AIDS case reporting law introduced definition (23 OIs) takes effect implemented AIDS case definition HIV-related cause NYS expands AIDS expanded of death reporting reporting to (CD4 <200, 26 OIs) begins include HIV AIDS case reporting mandated by NYS • HIV surveillance expands to include all HIV-related laboratory reports *2013 *2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 0 1982 0 1981 Number of New HIV/AIDS Diagnoses and Deaths 14,000 PLWHA=Persons living with HIV/AIDS *Data on 2012 and 2013 deaths are incomplete. Data as reported to NYC DOHMH by June 30, 2014. HIV in NYC, 1981-2013 2013: 2,832 new HIV diagnoses 1,784 new AIDS diagnoses 1,527 deaths among PWH PLWHA=Persons living with HIV/AIDS *Data on 2012 and 2013 deaths are incomplete. Data as reported to NYC DOHMH by June 30, 2014. HIV Diagnoses, 2001-2013 Data as reported to NYC DOHMH by June 30, 2014. New HIV Diagnoses and Estimated Incidence in NYC, 2009-2013 5,000 4500 4000 3599 3584 3141 3,353 2,000 3,225 3146 2927 3,000 2500 2000 3474 3,705 3000 Number Number of HIV cases 4,000 3500 3936 4256 2,990 2,832 2733 2,597 2,718 2,284 2,230 2076 1,894 1500 1000 1,000 500 0 0 2008 2009 2009 2010 Newdiagnoses diagnoses of HIV New of HIV 2010 2011 2011 2012 Year Year of diagnosis Estimated HIV incidence Estimated HIV Incidence 2012* 2013* *2013 incidence data are preliminary. generated September 2014, by the CDC Stratified Extrapolation Approach (SEA). SEA combines results from the Serologic Testing Algorithm for Recent Seroconversion (STARHS) with data on demographic characteristics, risk factor, initial diagnosis date, testing and treatment history that are contained in the HIV surveillance registry. Unknown risk factor was imputed using the Multiple Imputation procedure in SAS v9.2. Surveillance data used in these estimates were reported through June 30, 2014. 1Estimates Geographic Distribution of HIV in NYC, 2013 • • • ZIP codes in the Central Harlem-Morningside Heights, Chelsea-Clinton, and WilliamsburgBushwick neighborhoods had the highest HIV diagnosis rates. ZIP codes in Chelsea-Clinton, West Queens, and East Harlem had the highest HIV prevalence. ZIP codes in Lower Manhattan, Stapleton-St. George, and Willowbrook had the highest mortality among persons with HIV. Data as reported to NYC DOHMH by June 30, 2014. HIV diagnoses includes diagnoses of HIV without AIDS and HIV concurrent with AIDS. ¹Diagnosis rates and percentages calculated using the intercensal 2013 NYC population. ²2013 death data are incomplete. ³Death rates are age-adjusted to the NYC Census 2010 population. HIV Diagnosis Rates1 Among Males and Females in NYC by Race/Ethnicity2, 2013 The HIV diagnosis rate among black males was 1.5 times higher than the rate among Hispanic males and over 2 times higher than the rate among white males. 180 150 The HIV diagnosis rate among black females was over 2 times higher than the rate among Hispanic females and over 9 times higher than the rate among white females. 180 143.7 150 120 120 93.5 90 90 50.8 60 60 26.1 30 42.5 30 18.0 4.3 2.1 White API 0 0 Black Hispanic White API Black Hispanic Data as reported to NYC DOHMH by June 30, 2014. API=Asian/Pacific Islander 1Includes diagnoses of HIV without AIDS and HIV concurrent with AIDS. 2Native American and multiracial groups not shown because of small numbers. New HIV Diagnoses Among MSM in NYC, 2009-2013 New HIV (non-AIDS) diagnoses (N) Overall: 4.3% decline Younger MSM: Stable Older MSM: 8.8% decline 1,200 13-29 years 30+ years 1,000 844 879 845 857 839 868 852 824 800 847 802 600 400 200 0 2009 2010 2011 Year of Diagnosis 2012 2013 Since 2012, the number of new HIV diagnoses is higher among MSM under age 30 than among those in older age groups Data as reported to NYC DOHMH by June 30, 2014. MSM risk category includes men who have sex with men and inject drugs (MSM-IDU). Estimated HIV Incidence Among MSM in NYC, 2009-2013 Estimated HIV Incidence among MSM Overall Estimated HIV Incidence among MSM <30 Estimated HIV Incidence among MSM ≥30 2,000 1,584 1,487 Number of HIV cases 1,500 1,406 1,321 1,246 1,000 816 796 684 775 648 767 500 691 637 631 597 0 2009 2010 2011 2012 2013* Year of diagnosis *2013 incidence data are preliminary. generated September 2014, by the CDC Stratified Extrapolation Approach (SEA). SEA combines results from the Serologic Testing Algorithm for Recent Seroconversion (STARHS) with data on demographic characteristics, risk factor, initial diagnosis date, testing and treatment history that are contained in the HIV surveillance registry. Unknown risk factor was imputed using the Multiple Imputation procedure in SAS v9.2. Surveillance data used in these estimates were reported through June 30, 2014. 2MSM includes persons reporting both MSM and injection drug use history. 1Estimates New HIV Diagnoses Among MSM by Race/Ethnicity* in NYC, 2009-2013 700 Number of new HIV diagnoses 600 500 400 Black MSM Hispanic MSM White MSM 300 Asian/Pacific API MSM Islander 200 100 0 2009 2010 2011 2012 2013 Year of diagnosis Data as reported to NYC DOHMH by June 30, 2014. American and multiracial groups not shown due to small numbers. MSM risk category includes men who have sex with men and inject drugs (MSM-IDU). *Native Age-adjusted Death Rates Among Persons with HIV in NYC, 2000-2013 Age-adjusted¹ death rates per 1,000 mid-year PLWHA 40 35 HIV-related 30 Non-HIV-related All-cause 3 25 20 15 10 5 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Year of death 2009 2010 2011 2012 2013 2 Data as reported to NYC DOHMH by March 31, 2015. ¹Age-adjusted to the NYC Census 2010 population. ²2013 deaths outside NYC are incomplete. ³Includes persons with unknown cause of death. Age-adjusted HIV-related Death Rates in NYC by Race/Ethnicity, 2000-2013 Age-adjusted¹ death rates per 1,000 mid-year PLWHA 40 35 Hispanic Asian/Pacific Islander 30 Black White 25 20 15 10 5 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Year of death 2009 2010 2011 2012 2 2013 Data as reported to NYC DOHMH by March 31, 2015. ¹Age-adjusted to the NYC Census 2010 population. ²2013 deaths outside NYC are incomplete. Age-adjusted HIV-related Death Rates in NYC by Transmission Risk Category, 2000-2013 Age-adjusted¹ death rates per 1,000 mid-year PLWHA 35 30 MSM IDU 25 Heterosexual 20 15 10 5 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Year of death 2009 2010 2011 2012 2013 2 Data as reported to NYC DOHMH by March 31, 2015. ¹Age-adjusted to the NYC Census 2010 population. ²2013 deaths outside NYC are incomplete. HIV-related Death Rates in NYC by Age Group, 2000-2013 60.0 Death rates per 1,000 mid-year PLWHA 50.0 40.0 0 - 12 13 - 19 20 - 29 40 - 49 50 - 59 60+ 30 - 39 30.0 20.0 10.0 0.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013¹ Year of death Data as reported to NYC DOHMH by March 31, 2015. ¹2013 deaths outside NYC are incomplete. Number and Proportion of Persons with HIV in New York City Engaged in Selected Stages of the Continuum of HIV Care in 2013 100% 100% 64% Suppressed 86% 80% Percentage 79% 74% 64% 60% 40% 20% 0% HIV-infected Diagnosed Retained in care Prescribed ART Virally suppressed N=94,912 N=81,625 N=74,590 N=70,488 N=60,547 Xia Q, Kersanske LS, Wiewel EW, Braunstein SL, Shepard CW, Torian LV. Proportions of patients with HIV retained in care and virally suppressed in New York City and the United States. J Acquir Immune Defic Syndr. 2015;68(3):351-358. Includes patients receiving care in NYC but living outside of NYC (N=4,794). 14% of PLWH undiagnosed. Retained in care: ≥1 care visit in 2013. 94.5% of patients who were retained in care prescribed ART (source: MMP 2012). Viral suppression defined as VL ≤200 cc/mL. Data as reported to NYC DOHMH by June 30, 2014. Number and Proportion of Persons with HIV in New York City Engaged in Selected Stages of the Continuum of HIV Care in 2013 by Borough Virally suppressed 100% Bronx: 61% Queens: 64% Brooklyn: 63% Staten Island: 59% Manhattan: 68% Percentage 80% 60% Bronx Brooklyn Manhattan 40% Queens Staten Island 20% 0% HIV-infected Diagnosed Retained in care Xia Q, Kersanske LS, Wiewel EW, Braunstein SL, Shepard CW, Torian LV. Proportions of patients with HIV retained in care and virally suppressed in New York City and the United States. J Acquir Immune Defic Syndr. 2015;68(3):351-358. Prescribed ART Virally suppressed 14% of PLWH undiagnosed. Retained in care: ≥1 care visit in 2013. 94.5% of patients who were retained in care were prescribed ART (source: MMP 2012). Viral suppression defined as VL ≤200 cc/mL. Data as reported to NYC DOHMH by June 30, 2014. Number and Proportion of Persons Newly Diagnosed with HIV in New York City in 2012 Engaged in Selected Stages of the Continuum of HIV Care 100% 100% 80% 66% Suppressed 84% 69% (≤3 mos) 60% 73% 66% 40% 20% 0% Newly diagnosed Linked to care Established in care Virally suppressed N=2,990 N=2,521 N=2,188 N=1,961 Wiewel EW, Braunstein SL, Xia Q, Shepard CW, Torian LV. Monitoring outcomes for newly diagnosed and prevalent HIV cases using a care continuum created with New York City surveillance data. J Acquir Immune Defic Syndr. 2015;68(2):217-226. Linked to care: ≥1 lab after a 7-day lag within 18 months of diagnosis. Established in care: ≥2 labs ≥3 months apart within 18 months of diagnosis. Virally suppressed: ever achieved viral suppression (≤200 cc/mL) within 18 months of diagnosis. Data as reported to NYC DOHMH by June 30, 2014. Viral suppression* at 6 and 12 months after HIV diagnosis, NYC, 2008-2013 70% 64.0% 57.8% 60% 53.4% % Virally suppressed 50% 46.6% 45.6% 40.4% 40% 39.6% 36.3% 35.2% 29.5% 30% 25.7% 23.8% 20% 10% 0% By 6 months By 12 months 2008 By 6 months By 12 months 2009 By 6 months By 12 months 2010 By 6 months By 12 months 2011 By 6 months By 12 months 2012 By 6 months By 12 months 2013 Data as reported to NYC DOHMH by March 31, 2015. *Viral suppression is defined as an HIV RNA level ≤200 copies/mL following HIV diagnosis. Thank you [email protected]
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