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Development of chemical tools for promoting iPS cell self renewal
Gu Liu,1 Elizabeth Couper,2 Carole J. R. Bataille,1 Len Seymour,3 Mark Stephenson,3 Camilo E.
Quevdo,1 Graham M. Wynne,1 Stephen G. Davies1*, Sally Cowley,2* and Angela J. Russell1,4*
Disease modelling
Reprogramming
Differentialtion
iPS cells
Neuronal cells
Drug testing
Somatic cells
Toxicity testing
Patient
e.g. Parkinson's Disease
Current method: 2D-culture
Our Aim