Science Signaling: Research, Teach, and
Discover with the Weekly Journal
Devoted to Cellular Signal Transduction
Nancy R. Gough, Ph.D., Editor
Science Signaling
June 2011
What Is Signal Transduction?
Signal transduction is the molecular
processes by which cells respond to cues
in their internal or external environment.
Signal transduction mechanisms
are targets for drug development.
Signal transduction research is an intensely active field of biomedical
research and is of interest to a broad array of scientists.
330,683 results in PubMed for “signal transduction”
482,130 results in PubMed for “signaling OR signalling”
Who Studies Signal Transduction?
Signal transduction is multidisciplinary:
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Biochemistry
Bioinformatics
Cell Biology
Development
Host-Pathogen Interactions
Immunology
Microbiology
Molecular Biology
Neuroscience
Plant Biology
Pharmacology
Physiology and Medicine
Systems Biology
A Primary Research Journal
January 2008:
Change name from
Science’s STKE to
Science Signaling
September 2008:
First issue containing
Research Articles
August 2010:
First issue containing
Research Resources
53 selected in Faculty
of 1000
Indexed in PubMed, Google
and Google Scholar, and
Thomson Web of Science
Research Content
Research Articles
Research Resources
Hypothesis-driven research leading
to major advances in
understanding cell regulation,
especially research with
impact across multiple
disciplines in the biological
sciences
Nonhypothesis-driven papers
relevant to signal research,
including analysis of
validated datasets and
development of new tools,
methods or techniques
~8-12 per monthly
print compilation
~2 per month
print compilation
Journal Content
Editorial Guides
Editorials
Editors’ Choice
Research Articles
and Resources
Perspectives
Reviews
Protocols
Journal Club
Meeting Reports
Section
2010
Total
Research Articles
91
227
Research Resources
4
7
Perspectives
51
620
Reviews
10
148
Protocols
3
90
Editorial Guides
12
121
Editors’ Choice
392
5179
Meeting Reports
3
32
Journal Club
8
16
Teaching Resources
5
74
Podcasts
23
70
Presentations
2
18
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Weekly Electronic Journal
Monthly Print Compilation
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RESEARCHER
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Research Article
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Slides
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Cell Signaling
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Fig. 1 An extensively validated mammalian genome-wide siRNA
screen of the Wnt/{beta}-catenin signal transduction pathway
Published by AAAS
M. B. Major et al., Sci. Signal. 1, ra12 (2008)
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