This extended online version is produced by the Science/AAAS Custom Publishing Office Career Advice Innovation and Research: The Human Factor CREDIT: © ISTOCKPHOTO.COM/TOMML Continuous innovation and outstanding research are the most important attributes to respondents choosing this year’s best biotech and pharma companies—yet to top employers, their scientists’ ingenuity and enthusiasm are the real essentials for excellence. By Carol Milano The 2011 Science Careers Top Employers Survey was designed to identify the 20 companies with the finest reputations in the industry, as well as the characteristics that most impact an employer’s status. The results are based on 3,784 responses to a web-based survey (see “We choose people who survey methodology in chart below). Nearly half of the respondents aren’t afraid to take risks— are under 40 years old, 79 percent work in the United States, and 40 percent are female. by trying something new Besides innovation and research, survey respondents expect a or bringing a nontraditional leading company to be socially responsible, treat its employees with respect, and inspire their loyalty. This year, the #5 criteria—“has a idea forward—and who are top leadership that successfully makes changes needed to keep the not satisfied with the status organization moving in the right direction”—replaced 2010’s “has quo.” —Lisa Kelly-Croswell, a clear vision of where the organization is headed.” (See Driving Characteristics chart below.) senior vice president, Vertex The 2011 results brought a new, first-time #1 employer: Vertex Pharmaceuticals Incorporated (#3 in 2010). In fact, three of the highest-ranking companies are new to the top 20 list (see Top 20 Employers chart below for complete company listing). These shifts aren’t surprising, because “It’s been an interesting time in the industry,” observes Alan Smith, Genzyme Corporation’s chief scientific officer before its acquisition by Sanofi. “For us, the past year has been a period of upheaval, but we’ve regularly scored well in this survey,” he notes (Genzyme is #13 this year, #8 in 2010). Now chief science advisor for Sanofi Global Research and Development, he says, “As part of Sanofi, we’ll take the approach we’ve used at Genzyme and apply it more generally.” Other top employers are entering new phases, too. Vertex recently introduced their first drug, Incivek, to the market, and has begun been building their first commercial team. “This [survey] recognition is tied directly to the passion and creativity that our 1,800 employees bring to Vertex 1 FOCUS ON CAREERS Produced by the Science/AAAS Custom Publishing Office Employers 2011 2010 Rank Rank Employer (Global Headquarters) Vertex Pharmaceuticals Incorporated (Cambridge, MA) 1 3 Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) 2 – Genentech (South San Francisco, CA) 3 1 4 19 Pioneer Hi-Bred, a DuPont business (Johnston, IA) 5 4 Millennium: The Takeda Oncology Company (Cambridge, MA) 6 10 Amgen (Thousand Oaks, CA) Boehringer Ingelheim (Ingelheim, Germany) 7 6 Syngenta (Basel, Switzerland) 8 7 Novo Nordisk (Bagsvaerd, Denmark) 9 – 10 15 Biogen Idec (Weston, MA) 11 13 Abbott (Abbott Park, IL) Merck KGaA/Merck Serono/EMD Serono (Darmstadt, Germany) 12 9 Genzyme Corp. (Cambridge, MA) 13 8 14 11 Novartis (Basel, Switzerland) Roche (Basel, Switzerland) 15 5 Monsanto Company (Creve Coeur, MO) 16 2 17 14 Eli Lilly and Company (Indianapolis, IN) 18 17 Gilead Sciences (Foster City, CA) 19 20 AstraZeneca PLC (London, UK) Bayer (Leverkusen, Germany) 20 – SURVEY METHODOLOGY Inn Top Twenty ov at i ve Tre lea at s de em r in p t he Is s loy oci ee ind sw all us yr i tr y t h Ha esp res s lo on pe ya s ib l ct l em e Ma plo ke s y ee c ha s Do ng es es ne im ed po ed r ta nt , qu ali ty res ea rc h TOP EMPLOYERS SURVEY æs æs æs ææs æs æs æs ææs ææs æs ææs ææs æs ææs ææs ææs æs ææs æs æs æs ææs æs ææs æs ææs ææs æs ææs æs æs ææs ææs æs æs æs ææs æs ææs æs ææs ææs ææs s s s s s s s s s s s s s s s s s This web-based survey was conducted from March 24 to April 11, 2011 by Brighton Consulting Group and Cell Associates. For this year’s survey, a mixed methodology was again used. The first part of this methodology included e-mailed invitations to roughly 46,000 individuals who were located worldwide. These individuals were Science website visitors who have registered with AAAS and past survey respondents. This year Facebook, Twitter, and online banner ads were also used to promote participation in this survey. Forty-two percent of all surveys submitted were from this first effort. The second part of the methodology included an e-mail blast to a list of about 500 human resource contacts at industry firms that were pulled from the Science Careers sales database. The remaining 58 percent of the surveys were from this second effort. This report is based on a total sample of 3,784 survey respondents. The 20 companies with the best reputations as employers and the top three driving characteristics for each company, according to respondents in the 2011 survey undertaken for the Science/AAAS Custom Publishing Office. The companies without a 2010 rank did not rank among the top 20 in the 2010 survey. each we seek toresearch change thedone lives of being peoplewant with devastating says Peter Mueller, knownday, withinas their field for the they’ve or for to be, not what wediseases,” are today,” says Vertex’s Mueller, who thought leaders. ” science officer and executive vice president looks for people with “the scientific and and technologic expertise Vertex’s chief for global research development. Bayer’s U.S. division seeks scientists with the “ingenuity, to take Vertex to the next frontier, and the courage to constantly Regeneron Pharmaceuticals, Inc. (#2, and new to the top 20 list) has a treatment for a major curiosity, and enthusiasm for working at an organization striving for move the frontier forward. In science, experiments often have eye disease under FDA review. Later this year, seek FDA approval a new cancer drug innovations that make a difference in the world, ” summarizes Bryanthey’ll unexpected outcomes. Some for scientists have the willingness and additional application for Arcalyst, their product on uncertainty. the market. Arcalyst Iams,request director ofan external communications. “In a global company and joy first to deal with this That’sSince the phenotype operating in everyfor country, can genetic they be respectful and understand we’re for.” was created a rare condition, Regeneron is looking now essentially developing a brand-new that in different cultures, different beliefs drive people?” he asks. Mueller wants his scientists “maximally integrated across all funcsales and marketing function. Explains Ross Grossman, human resources vice president, “We’ve With 108,000 employees worldwide, the Germany-based company tions—research, development, commercial, legal, human resources, focused a great energy a true biotech culture—[stressing] innovation and fungreat (#20; reappearing on deal the listofsince being on #19 retaining in 2006) looks for accounting—so they can communicate and collaborate. That’s science—as we’ve and matured as a company. It’stoespecially gratifying toand bedeveloping recognized by versatility and the kind ofgrown entrepreneurial thinking encouraged at damental our ultimate goal: Discovering transforBayer’s “innovation in China, Europe, and California. mational medicines. Science for ourcenters” science-driven culture, and“These to come out so high”in our first year.” then hook into and get translated into our larger global organization,” prefers highly-trained scientists, several years beEight of this year’s top 20 companies are based yond inGenzyme Europe. Global collaborations and concerns are explains Iams. their Ph.D.s. “Our best hires, in a creative sense, have increasingly important to leading biotech/pharma companies, pay carefulThey’re attention to their “It’s sometimes easy to hire someone just because they are an about five years which of postdoc experience. really where the exceptional scientist, but and we spend ample time find a person with excitement is in research—and they’reinexciting to be around,” research facilities services in to developing countries. Health care providers less-developed the technical alsoaccess fits with to ourthe core newest values,” says Lisa says Smith. areas mayskills not who have medical procedures and pharmaceutical treatments. Kelly-Croswell, Vertex senior vice president for human resources. In 2008, needing several hundred additional employees for a Denmark-based Novo Nordisk (#9 this year, and also new to the top 20 list) is one “We choose people who aren’t afraid to take risks—by trying some- new collaboration with Sanofi-Aventis, Regeneron worked with pharmaceutical that addressing specific international need. thing new or bringingcompany a nontraditional ideaisforward—and whoa are a recruitment and branding firm Diabetes to attract thetreatments right people. They not satisfiedfor with the status ” launched an online ad campaign, highlighting account about 75quo. percent of Novo Nordisk’s business. They provide training aboutwhat bestGrossman practices Their research and development group hires “for what we calls their “quirkiness and selectivity, ” by presenting their in diabetes care for thousands of physicians in China. “Diabetes doesn’t get the attention it recently deserves there because of limited resources,” observes Steve Chinn, vice president for human 250resources. “We’re striving to be a partner www.sciencecareers.org with the Chinese health care system, not simply as just a maker of medicine, but by doing more to help educate and inform patients and physicians about the severity of the disease.” 2 FOCUS ON CAREERS Produced by the Science/AAAS Custom Publishing Office TOP EMPLOYERS SURVEY different perspective and understanding, so we can expand globally,” SELECTING THEhuman SCIENTISTS explains Susan Bunz, resources and corporate services vice Being an “innovative president at Pioneer Hi-Bred,leader” a Dupontcontinues business, theto plant genetics be the most powerful forleap selecting a 2010). The company that ranked #4 this driver year (a big from #19 in Iowa-based company’s plus scientists at 110 company as a top 3,000 employer. When work asked to research locations in “what 24 countries. “Ourthe culture is very collaborative. People describe makes best company, GENDER share a ‘can do’ attitude, want to work in a very dynamic environthe best,” survey respondents specifically 57% Male, 40% Female, 3% No response ment, and know how to complete a project.” mentioned “supports a culture of innovation,” EXPERIENCE “employee-driven curiosity,” and “innovative RETAINING OUTSTANDING SCIENTISTS 64% have 10 years or more of work experience ideas of everyone areareconsidered.” The world’s best scientists always on recruiters’ radar screens, and employers know that people often change “It’s one thing to HIGHEST DEGREE EARNED How do top employers create an jobs. innovative attractinspiring new talent,corporate another to retain them,” says Bayer’s Iams. 42% Doctorate, 26% Master's, 27% Bachelor's, and atmosphere? Among “You must provide an environment that recognizes accomplish5% Other many highly qualified applicants, they search ment and celebrates the entire team,” Iams continues. Bayer offers for theprograms, exceptional most likely to so an emCOMPANY TYPE growth such asscientists internal education activities, 53% Biotech, 34% Pharma, 7% University, bring fresh, original ideas to the company. ployee always feels, “I’m learning here.” Motivators include letters 6% Other; more than four out of five work in Novo Nordisk, Chinn specifies of At recognition, awards (some monetary), andone performance-based private industry bonuses, which are sometimes company shares. priority: “Passion about reinvested diabetesinto and However, manythe biotech/pharma companies are moving NATURE OF WORK hemophilia,” two diseases for which theaway from broad eligibility for stock options, according to Grossman. Regen36% Development, 33% Applied Research, 27% Basic company creates medications. “We want eron, though, remains “absolutely committed to employee ownerResearch, 13% Administrative/Executive, 11% QA/QC/ people who Regulatory Affairs, 19% Other (Respondents were able to ship. Every neware hire very will beknowledgeable a shareholder.” Theand company recently educated about these disease states, and University choose more than one response.) introduced an on-site “mini-MBA program” with Rutgers professors a broadtheir view field of thefor industry’s who are presenting known within the business isGEOGRAPHY sues. Beyond classrooms, givebeing scientists very challenging research they’ve done“we or for thought 80% from North America; 12% from Europe; roles, where they can contribute to the fullest extent of their abilileaders.” 6% from Asia/Pacific Rim; 2% from rest of world ties,” adds Grossman. Bayer’s U.S. division seeks scientists with From microbiology to etymology to agronomy, Pioneer Hi-Bred the enthusiasm uses “ingenuity, a diverse rangecuriosity, of expertise.and A scientist’s specific assignment for working at an for Ph.D.s are formalized corporate values (“The Regeneron 5”), through reverse depends somewhat on organization his or her degree,striving explains Bunz. psychology: that make a difference in the world,” summarizes at the senior scientist level; director a B.S.-degree holder would be an asinnovations Bryan Iams, of external sociate or assistant to the and educational support communications. “In a global company operating in every country, canresearcher. they beThanks respectful sæ If science isn’t obsession—DON’T APPLY Pioneerpeople?” provides, “employees can go108,000 back to school while they’re understand thatyour in different cultures, different beliefs drive he asks. With sæ If you’re content being the smartest person in the room— here, when they see that additional education will increase their proemployees worldwide, the Germany-based company (#20; reappearing on the list since being DON’T APPLY motional opportunities.” #19 in 2006) looks for versatility and the kind of entrepreneurial encouraged at Bayer’s sæ If you’re afraid to fail—DON’T APPLY Novo Nordiskthinking encourages scientists to “focus on a specific job “innovation in is China, Europe, andAPPLY California. “These then get and translated intodevelopsæ If you thinkcenters” good enough good enough—DON’T aspect that will hook forwardinto their and research, their personal If you need a routine to define you—DON’T APPLY ment,” says Chinn. Every employee is required to prepare an “Indioursælarger global organization,” explains Iams. vidualare Development Plan.” Theyscientist, can opt to attend symposia, specific “It’s sometimes easy to hire someone just because they an exceptional but we By the year’s time end, Regeneron its goal of hiring 350 highly skills educational otherour learning The company spend ample to find amet person with the technical who programs, also fits or with coreopportunities. values,” says qualified new employees. gladly provides tuition “to further their employees’ education. We Lisa Kelly-Croswell, Vertex’s senior vice president ofhope human resources. “We choose people who Genentech, a member of the Roche group, (#3 in 2011; #1 in eight it’s holistic—not just to help Novo Nordisk, but to improve their aren’t afraid to take risks—by trying something new or bringing a nontraditional out of the 10 years of surveys) is continuously recognized for its own specialized skills,” he explains.idea forward—and who are not satisfied with the status innovative leadership, high-quality research, and quo.” talent pool. GenenVertex holds weekly “social hours” where scientists and other tech’s makers aredevelopment extremely respectful of the company’s staff share The are company also has unique Theirdecision research and group hires “for what wemembers want to be,perspectives. not what we today,” scientists. Emphasizing excellent skills, with Genentech employee incentives, such as “the Vertex Nobel says Vertex’s Mueller, who communication looks for people “the scientific and technologic expertise toPrize” takefor outstandscreens for a strong publication record, because they feel that it ining research and the recently introduced Science Technology ExVertex to the next frontier, and the courage to constantly move the frontier forward. In science, dicates an ability to communicate well in writing. “Everyone I inchange Program (STEP), a sabbatical opportunity. Bench scientists experiments often have unexpected outcomes. Some scientists have willingness andout” joyofto deal terview is very bright, motivated, and accomplished, especially on whose proposals arethe accepted get to “STEP their usual roles with this uncertainty. That’s the phenotype we’re looking for.” the biology side,” observes Andy Chan, senior vice president of reand pursue a new path for three months. The program was develMueller wants integrated allseven functions—research, development, search biology. “Buthis theyscientists must really “maximally want to translate biology into across oped by Vertex scientists working in a focus group on improvmedicine. That’slegal, the driving force behind who comes to Genentech, they ing career and recognition. commercial, human resources, accounting—so can paths communicate and collaborate. That’s and why we’re to in the ” Some skilled scientific problem In many professions, accomplishments and recognition bring profundamental ourbusiness. ultimate goal: Discovering and developing transformational medicines.” solvers, Chan believes, are far better suited for academia. “We want motion into management. “For a scientist, that means moving away Genzyme prefers highly trained scientists, several years beyond their Ph.D.s. “Our best hires, in a the ones who want to make something happen that helps people.” from the bench,” Smith observes, “but you may not want to have a creative have about five of postdoc experience. reallytowhere the excitement is fourAt thesesense, top employers, research andyears development jobs aren’t hundred They’re people reporting you.” Genzyme offers a popular, inonly research—and they’re exciting to be around,” says Smith. for Ph.D.s. Throughout his organization, reports Novo Nordisk’s level alternative track: Fellow, Senior Fellow, Distinguished Fellow, In 2008, needing hundred employees for coveted a new slot collaboration with SanofiChinn, scientists work atseveral many different levels.additional At their Seattle site, and one as Presidential Fellow. “If you want to stay for example, some of theworked scientistswith doing a fundamental research at the bench, herethe can right be paidpeople. as much They as a senior vice Aventis, Regeneron recruitment andonbranding firm atoFellow attract new therapeutic areas have or Master’s degrees.what They’reGrossman president. calls It’s a great to keep people who may not want manlaunched an online ad Bachelor’s campaign, highlighting theirway “quirkiness and selectivity,” working alongside M.D.s and Ph.D.s. agement, but want to progress. It’s very effective—these are such by presenting their recently formalized corporate values (“The Regeneron 5”), through reverse “This is such a diverse organization, we want people who bring a valuable people,” he says. psychology: CREDIT: © ISTOCKPHOTO.COM/ARENACREATIVE SURVEY DEMOGRAPHICS 252 •If science isn’t your obsession—DON’T APPLY www.sciencecareers.org •If you’re content being the smartest person in the room—DON’T APPLY •If you’re afraid to fail—DON’T APPLY •If you think good enough is good enough—DON’T APPLY •If you need a routine to define you—DON’T APPLY 3 By the year’s end, Regeneron met its goal of hiring 350 highly qualified new employees. Genentech, a member of the Roche group, (#3 this year; #1 in 8 out of 10 previous surveys) is continuously recognized for its innovative leadership, high-quality research, and talent pool. Genentech’s decision makers are extremely respectful of the company’s scientists. Emphasizing excellent communication skills, Genentech screens for a strong publication record, because they feel that it indicates an ability to communicate well in writing. “Everyone I interview is very bright, motivated, and accomplished, especially on the biology side,” observes Andy Chan, senior vice president of research biology. “But they must really want to translate biology into medicine. That’s the driving force behind who comes to Genentech, and why we’re in the business.” Some skilled scientific problem solvers, Chan believes, are far better suited for academia. “We want the ones who want to make something happen that helps people.” At these top employers, research and development jobs aren’t only for Ph.D.s. Throughout his organization, reports Novo Nordisk’s Chinn, scientists work at many different levels. At their Seattle site, for example, some of the scientists doing fundamental research on new therapeutic areas have Bachelor’s or Master’s degrees. They’re working alongside M.D.s and Ph.D.s. “This is such a diverse organization, we want people who bring a different perspective and understanding, so we can expand globally,” explains Susan Bunz, human resources and corporate services vice president at Pioneer Hi-Bred, a Dupont business, the plant genetics company that ranked #4 this year (a big leap from #19 in 2010). The Iowa-based company’s 3,000 plus scientists work at 110 research locations in 24 countries. “Our culture is very collaborative. People share a ‘can do’ attitude, want to work in a very dynamic environment, and know how to complete a project.” RETAINING OUTSTANDING SCIENTISTS The world’s best scientists are always on recruiters’ radar screens, and employers know that people often change jobs. “It’s one thing to attract new talent, another to retain them,” says Bayer’s Iams. “You must provide an environment that recognizes accomplishment and celebrates the entire team,” Iams continues. Bayer offers growth programs, such as internal education activities, so an employee always feels, “I’m learning here.” Motivators include letters of recognition, awards (some monetary), and performance-based bonuses, which are sometimes reinvested into company shares. However, many biotech/pharma companies are moving away from broad eligibility for stock options, according to Grossman. Regeneron, though, remains “absolutely committed to employee ownership. Every new hire will be a shareholder.” The company recently introduced an on-site “mini-MBA program” with Rutgers University professors presenting a broad view of the industry’s business issues. Beyond classrooms, “we give scientists very challenging roles, where they can contribute to the fullest extent of their abilities,” adds Grossman. From microbiology to entomology to agronomy, Pioneer Hi-Bred uses a diverse range of expertise. A scientist’s specific assignment depends somewhat on his or her degree, explains Bunz. Ph.D.s are at the senior scientist level; a B.S.-degree holder would be an associate or assistant researcher. Thanks to the educational support Pioneer provides, “employees can go back to school while they’re here, when they see that additional education will increase their promotional opportunities.” Novo Nordisk encourages scientists to “focus on a specific job aspect that will forward their research, and their personal development,” says Chinn. Every employee is required to prepare an “Individual Development Plan.” They can opt to attend symposia, specific educational programs, or other learning opportunities. The company gladly provides tuition “to further their employees’ education. We hope it’s holistic—not just to help Novo Nordisk, but to improve their own specialized skills,” he explains. Vertex holds weekly “social hours” where scientists and other staff members share perspectives. The company also has unique employee incentives, such as “the Vertex Nobel Prize” for outstanding research and the recently introduced Science Technology Exchange Program (STEP), a sabbatical opportunity. Bench scientists whose proposals are accepted get to “STEP out” of their usual roles and pursue a new path for three months. The program was developed by seven Vertex scientists working in a focus group on improving career paths and recognition. In many professions, accomplishments and recognition bring promotion into management. “For a scientist, that means moving away from the bench,” Smith observes, “but you may not want to have a hundred people reporting to you.” Genzyme offers a popular, four-level alternative track: 4 FOCUS ON CAREERS Produced by the Science/AAAS Custom Publishing Office TOP EMPLOYERS SURVEY values risk-taking, creativity, and scientific exploration, which spurs our scientists to succeed,” says Chan. “Once they make a breakthrough, it’s a very addicting feeling. Their suc2011 2010 cess encourages more emphasis on 1. Innovative leader in the industry 1. Innovative leader in the industry innovation.” With its “incredibly strong commit2. Treats employees with respect 2. Treats employees with respect ment to high-risk innovation, Vertex 3. Loyal employees 3. Socially responsible starts with a disease and finds a way 4. Socially responsible 4. Loyal employees to treat its underlying cause,” says 5. Clear vision 5. Makes changes needed Mueller. “We’re innovative in the way we partner, how we set ourselves up 6. Does important quality research 6. Does important quality research as an organization, how we reach out 7. Work and personal values are aligned in the community, and how we interact with patients and physicians. We balance risk on several shoulders, Black type indicates the characteristics in common for the two years. increasing our chances for success, “It’s easier to do well when things are going well,” Smith reflects, through our network of global partners.” “and hard to do well when times are tough. I’m very proud and For Pioneer Hi-Bred, global interconnections are internal. They’ve fellow, senior fellow, distinguished fellow, and one coveted slot as presidential fellow. “If you want pleased that we’ve scored well this year—it says that people are added 4,000 employees since 2007, in 95 locations. Research and toseeing stayand at believing the bench, a fellow here can be paid as much as a senior vice president. It’s a great Latin wayAmerica, in new opportunity here. We pay a lot of attendevelopment (R&D) scientists in Europe, Asia/Pacific, totion keep people who may notconvincing want management, to progress. very effective—these to how we convince and keep people that this but is a want and North America areIt’s in constant contact. “They knoware where the such people,” hea rough says.period. Very few people have soils are similar and who should be collaborating. One strategy may good valuable place to work even during left since the acquisition. ” be applicable in North South the same products “It’s easier to do well when things are going well,” Smith reflects, “andand hard toAmerica, do wellbut when don’t work globally, ” explains Bunz. times are tough. I’m very proud and pleased that we’ve scored well this year—it says that people INNOVATION AND RESEARCH Bayer takes a similar approach. “Collaboration at our worldwide are seeing and believing in new opportunity here. We pay a lot of attention to how we convince Two of the survey’s perennial top drivers—innovative leadership and locations is part of our model for success,” Iams emphasizes. “Sharand keep convincing people that this is a good place to work even today during a rough period. Veryfive few quality research—are never taken for granted at excellent compaing information is so much easier than even years ago. people havecarefully left since theand acquisition.” nies. They’re nurtured cultivated. Other scientists can access your files to further [distant] collabora“We’re highly committed to further strengthening our innovative tions. Now our high-growth regions are really learning from other capabilities—innovation is key to maintaining or gaining a leading polocations, allowing much faster development in China, India, and INNOVATION AND RESEARCH sition in every market in which we operate, and also the foundation Latin America. ” All quality 2,500 Bayer scientists, engineers, and chemists Two of the survey’s perennial top drivers—innovative leadership and research—are never for improving the lives of many millions of people,” says Katharina in various labs are charged with driving innovation. taken for granted at excellent companies. They’re carefully nurtured and cultivated. Jansen, Ph.D., director of global media relations and issues man“We’re committed to further strengthening our innovative is key agementhighly for Bayer Schering Pharma AG in Leverkusen, Germany. ECONOMICcapabilities—innovation IMPACT toShe maintaining or gaining a leading position in every in which we operate, and the has led to layconsiders Bayer’s research and development investments to be market Survey respondents indicated that the softalso economy long-term: Their or agricultural av-of people,” offs, site closures, and outsourcing. When asked which key events foundation forpharmaceutical improving the lives ofresearch many projects millions says Katharina Jansen, director 10 years before reaching the marketplace. have had the greatest effect onAG the in industry over the past year, reoferage global media relations and issues management for Bayer Schering Pharma Leverkusen, To encourage Regeneron labs operate like a hybrid of spondents named mergers andlong-term: acquisitions, which Germany. Sheinnovation, considers Bayer’s research and development investments to be Theirhave created academe and business, Grossman explains. “We give researchers some instability and uncertainty. Yet, many top employers experipharmaceutical or agricultural research projects average 10 years before reaching the marketplace. a great deal of freedom, and encourage employees to suggest imenced surprisingly few effects during the lengthy global recession. To encourage innovation, Regeneron labs operate like a hybrid ofadequate academe and business, provements at the implementation level. Anyone comfortable with a “Bayer takes precautions that economic instabilities do Grossman explains.give-and-take “We give can researchers a great deal not of freedom, encourage scientific organization’s be part of any discussion impact R&D and activities, a priority employees on our agenda,” says Jansen. We’re not yet big enough toat have of channels, formal level. proBayer’s R&D investments increased €2.9 billion in 2009 to €3.1 tohere. suggest improvements thelots implementation Anyone comfortable with afrom scientific cedures, or hierarchies. The enemy iscan bureaucracy, ” heofsays. billionhere. in 2010 We’re and 2011. organization’s give-and-take be part any discussion not yet big enough to have is continuously new approaches, says Gross-The Another firm, Novo lotsRegeneron of channels, formalseeking procedures, or hierarchies. enemy international is bureaucracy,” heNordisk, says. has thrived, with 36 man, and asking at every stage, “What’s the next generation of techquarters of double-digit growth. “We actually grew, added employRegeneron is continuously seeking new approaches, ees, saysand Grossman, and asking at every nology?” He elaborates: “When it wasn’t fashionable, we invested brought new products to market last year,” says Chinn. stage, “What’s the next generation of technology?” “When wasn’t fashionable, in building a technology that was then highly innovative, and broughtHe elaborates: Regeneron also seems it countercyclical, having “hired two-thirds we in building a technology thatawas and brought uswere to our us invested to our first marketable product. Then we invented suite then of tech-highly of ourinnovative, employees since 2008, when we under 700. We’ll soon niques that led to Arcalyst. ” Although uses these suc-of techniques reach 1,800,” says “At the endAlthough of 2010, 43 percent of first marketable product. Then Regeneron we invented a suite thatGrossman. led to Arcalyst.” cessful techniques develop other drugs,techniques they’re also committed had been here onealso year or less.” Regeneron uses tothese successful to developemployees other drugs, they’re committed to to ongoing innovation. Like Regeneron, Genentech has been expanding. Since 2008, as ongoing innovation. Genentech concentrates on innovations in transformative therapy. cutbacks left talented professionals unemployed, the company has Genentech concentrates on innovations in transformative therapy. “Our strength is our patient “Our strength is our patient focus,” asserts Mike Varney, senior vice been “very lucky to hire some exceptionally qualified scientists,” focus,” asserts Mike drug Varney, senior vice president, “We constantly president, small molecule discovery. “We constantly work with small says molecule Varney. “Ourdrug small discovery. molecule group, and research in general, work clinical groupswhat’s to understand going with a growing, particular it’s treated, clinicalwith groups to understand going on with what’s a particular dis- on have been whiledisease, the rest of how the industry is contracting. Beease, howlimitations it’s treated, and limitations of existing This therapies. This ing little out of syncisallowed to cherry-pick the very best.” and the of the existing therapies. proximity toa the patient rare.us Even with portfolio proximity to the patient is center rare. Even with portfolio reviews, discusnot economics, the biggest variable for a Pioneer Hireviews, discussions around the patients, how to Weather, help them, and the is reality of improving sions center around the patients, how to help them, and the reality Bred. “We continue to create products to deal with weather factors,” patient’s life.” of improving a patient’s life.” says Bunz. An innovative new drought-resistant product, AQUAmax, Genentech’s culture encourages research. is “Genentech risk-taking, Genentech’s culture encourages ambitiousambitious research. “Genentech for areas with values a dry climate or too littlecreativity, rainfall for farming. New CREDIT: © ISTOCKPHOTO.COM/RAPIDEYE DRIVING CHARACTERISTICS and scientific exploration, which spur our scientists to succeed,” says Chan. “Once they make a breakthrough, it’s a very addicting feeling. Their success encourages more emphasis on innovation.” 254 With its “incredibly strong commitment to www.sciencecareers.org high-risk innovation, Vertex starts with a disease and 5 finds a way to treat its underlying cause,” says Mueller. “We’re innovative in the way we partner, how we set ourselves up as an organization, how we reach out in the community, and how we interact with patients and physicians. We balance risk on several shoulders, increasing our chances for success, through our network of global partners.” For Pioneer Hi-Bred, global interconnections are internal. They’ve added 4,000 employees since 2007, in 95 locations. Research and development (R&D) scientists in Europe, Asia/Pacific, Latin America, and North America are in constant contact. “They know where the soils are similar and who should be collaborating. One strategy may be applicable in North and South America, but the same products don’t work globally,” explains Bunz. Bayer takes a similar approach. “Collaboration at our worldwide locations is part of our model for success,” Iams emphasizes. “Sharing information today is so much easier than even five years ago. Other scientists can access your files to further [distant] collaborations. Now our high-growth regions are really learning from other locations, allowing much faster development in China, India, and Latin America.” All 2,500 Bayer scientists, engineers, and chemists in various labs are charged with driving innovation. ECONOMIC IMPACT Survey respondents indicated that the soft economy has led to layoffs, site closures, and outsourcing. When asked which key events have had the greatest effect on the industry over the past year, respondents named mergers and acquisitions, which have created some instability and uncertainty. Yet, many top employers experienced surprisingly few effects during the lengthy global recession. “Bayer takes adequate precautions that economic instabilities do not impact R&D activities, a priority on our agenda,” says Jansen. Bayer’s R&D investments increased from €2.9 billion (US$4.06 billion) in 2009 to €3.1 billion (US$4.34 billion) in 2010 and 2011. Another international firm, Novo Nordisk, has thrived, with 36 quarters of double-digit growth. “We actually grew, added employees, and brought new products to market last year,” says Chinn. Regeneron also seems countercyclical, having “hired two-thirds of our employees since 2008, when we were under 700. We’ll soon reach 1,800,” says Grossman. “At the end of 2010, 43 percent of employees had been here one year or less.” Like Regeneron, Genentech has been expanding. Since 2008, as cutbacks left talented professionals unemployed, the company has been “very lucky to hire some exceptionally qualified scientists,” says Varney. “Our small molecule group, and research in general, have been growing, while the rest of the industry is contracting. Being a little out of sync allowed us to cherry-pick the very best.” Weather, not economics, is the biggest variable for Pioneer Hi-Bred. “We continue to create products to deal with weather factors,” says Bunz. An innovative new drought-resistant product, AQUAmax, is for areas with a dry climate or too little rainfall for farming. New products have to be tested in-ground in a target-type location, but uncooperative weather can prevent planting. In areas with a single growing season, that can delay testing for an entire year. CORPORATE CULTURE Three of this year’s top five drivers reflect workplace values and environment. To survey respondents, outstanding employers are socially responsible and have loyal employees whom they treat with respect. “What we do to shape our culture comes from listening to employees,” notes Vertex’s KellyCroswell. “We hold numerous focus groups, often in-the-moment. We take what we hear and translate it into action. Employees routinely tell us, ‘Hey, thanks for asking.’” Leading companies often codify their corporate values, as exemplified by “The Regeneron 5.” “Not only do we hire scientists who will treat patients with respect, we also expect them to respect each other,” asserts Chinn. The recently revised “Novo Nordisk Way” stresses accountability and responsibility. “Our employees have a right and a responsibility to say something if they see people not treating someone else well. Being an organization focused on just a few therapeutic areas, rather than many, makes us different, and gives us a shared sense of commitment.” Bayer, too, recently updated its global corporate values statement, choosing an acronym easily remembered in many languages: LIFE. It stands for Leadership, Integrity, Flexibility, and Efficiency. The company seeks to keep its culture consistent throughout all locations. “LIFE encourages 6 FOCUS ON CAREERS AAAS/Science Business Office Fe TOP EMPLOYERS SURVEY 2010. “That’s a big part of we are,” says Novo Nord Chinn. “We know we have nancial responsibility to s holders, and we also a social and environm 100 Vertex responsibility.” 95 Chan praises Genentec Genentech its “significant infrastru 90 Millennium/ Takeda Pioneer Hi-Bred and philanthropic funds to 85 Regeneron patients copay for me Boehringer 80 Syngenta tions.” Since 1985, when Ingelheim first product was appro 75 Biogen Amgen the company has dispe 70 Idec US$2.3 billion of free me Novo 65 tions in the United States BUBBLE WIDTH = SOCIALLY RESPONSIBLE Nordisk nentech’s Access To Care F 60 60 65 70 75 80 85 90 95 100 dation is based on the prin that no patient should INNOVATIVE go without a Genentech because of inability to pay Comparison of the top 10 companies on the basis of the top three drivers (scored out of 100): Socially responsible The top bio/pharma co (bubble width), Innovative leader (x-axis), and Treats employees with respect (y-axis). nies are also particularly p products have to be tested in-ground in a target-type location, but of their science education programs, both local and distant. S individual employees makecan decisions, to take the with leada whenever they see over things theystudents think in could uncooperativeto weather prevent planting. In areas single the late 1990s, 2 million Asia have participat season, that delay testing for an entire Bayer’s youth environmental programs,see which educate schoo be changedgrowing or adapted. Thecan culture empowers ouryear. research scientists to think independently, dren the aboutcompany the sciencemove and technology that is available to hel ideas and solutions, and propose or just implement whatever helps towards our CORPORATE CULTURE dress current environmental problems. larger vision,” Iams summarizes. Three of this year’s top five drivers reflect workplace values and Regeneron cosponsors the Westchester County National “This is the only place I’ve ever worked,” declares Vertex’s Kelly-Croswell, “where everyone can environment. To survey respondents, outstanding employers are Science and Engineering program, and sends its BioBus to recite our core values, because we allemployees live them: Fearless of excellence; innovation is ourto introduce kids to socially responsible and have loyal whom they treatpursuit with schools. The rolling science lab is designed life-blood; and ‘we’ wins.” respect. makes science so exciting. “We also have 75 high-school and “What we do to shape our culture comes from listening to em- lege interns,” says Grossman, “and we’ve come full-circle. On ployees,” notes Vertex's Kelly-Croswell. “We hold numerous focus our high school interns now is a patient who suffers from the c SOCIAL RESPONSIBILITY groups, often in-the-moment. We take what we hear and translate tion that our first drug treats.” Social responsibility is increasingly significant to both survey respondents and excellent employers. it into action. Employees routinely tell us, ‘Hey, thanks for asking.’” In Vertex’s STEM (Science, Technology, Engineering, and M It rose from Leading ranking #5 in 2010 to #3 this year.values, The increased among companies often codify their corporate as exempli- emphasis matics) Initiative, staff survey scientists volunteer in local schools in ne respondents mirrors a global trend: Eighty-six percent of citizens worldwide believe companies fied by “The Regeneron 5.” “Not only do we hire scientists who will communities, and engage that kids to become enthusiastic abou need to place least with as much on society’s interests they on business interests, treatatpatients respect,emphasis we also expect them to respect each as ence. Thedo company works with United Way to bring eight-to other, ” asserts Chinn. recently Global revised “Novo Way” (www.goodpurposecommunity.com). year-olds to Vertex’s headquarters for hands-on science explora according to a 2010 study byThe Edelman PublicNordisk Relations stresses accountability and responsibility. “Our employees Apart from their academic and motivational benefits to stud The highest-ranking companies in the Science Careers have Top aEmployers Survey take environmental right and a responsibility to say something if they see people not (and strong appeal to staff scientists), science education effort concerns and community involvement seriously. Many larger companies have foundations that treating someone else well. Being an organization focused on just valuable for high-achieving bio/pharma companies. “These typ manage their philanthropic and humanitarian efforts. The traditions are are especially strong in Mueller declares. “Un a few therapeutic areas, rather than many, makes us different, and programs mission-critical, ” Vertex’s European-based businesses. gives us a shared sense of commitment.” nately, in our society the science and technology track is no lo Bayer, for example, beganupdated demonstrating a strong environmental issues early Bayer, too, recently its global corporate valuesconcern statement,for the most wanted. We have toas engage kids when they’re youn easily in many languages: LIFE. Itto partner that science becomes understandable to them, and fun. As a as 1901. Inchoosing 2004, an it acronym became theremembered first private-sector business with the United Nations stands for Leadership, Integrity, Flexibility, and Efficiency. The com- pany, but the also late as a society, we needhas to nurture and inspire f Environment Programme in the areas of youth and environment. Since ‘90s, Bayer pany seeks to keep its culture consistent throughout all locations. scientists.” annually given €$1.2 million (US$1.68 million) plus noncash contributions for environmental “LIFE encourages individual employees to make decisions, to take Top employers invest in developing a stream of eager, cu education programs. Overthey twosee million students in Asia have or participated in these environmental the lead whenever things they think could be changed future scientists because they recognize that, as Genzyme’s education programs. In Bayer’s Young Environmental Envoy Program, students chosen by their adapted. The culture empowers our research scientists to think inde- Smith attests, “Your most precious resource is your people.” home communities in fast-growing, emerging economies—including Thailand, Brazil, Chile, China, pendently, see ideas and solutions, and propose or just implement whateverEcuador, helps the company move towards ouran larger vision,” Iams Carol Milano is an independent in New York City, covering Colombia, Kenya, and Korea—attend intensive one-week study program injournalist Germany. health and science. “They gain summarizes. first-hand experience in the principles and applications of care modern environmental “This is the only place I’ve ever worked,” declares Vertex’s Kellyprotection, and learn how industry, government, and private households interact in environmental Croswell, “where everyone can recite our core values, because we programs,” all explains live them:Iams. fearless pursuit of excellence; innovation is our lifeTo hear the Top Employers Podcast and read the extended “With ourblood; Danish heritage, into Novo Nordisk,” and ‘we’ wins.” social responsibility was essentially built online social responsibility content, see online version RESPECT COMPARISON OF TOP TEN'S TOP CHARACTERISTICS explains Chinn. “It’s such a big part of who we are. We know we have a financial responsibility to www.sciencecareers.org/TopEmployers2011 SOCIAL RESPONSIBILITY shareholders—and we also have a social and environmental responsibility.” Social responsibility is increasingly significant to both survey million) reInitially, the company donated DKK$650 million (US$122 for a 10-year period. In 2008, spondents and excellent employers. It’s the #3 driver, up from #5 in DOI: 10.1126/science.opms.r1100109 shareholders approved an additional DKK$575 million (US$108 million) for the next decade. Although the foundation operates independently, Novo Nordisk’s Chief Executive Officer, Lars www.sciencecareers.org Rebien 256 Sørenson, is on its board of directors. The World Diabetes Foundation focuses on neglected areas of diabetes care, such as preventing 7 unnecessary foot amputations or blindness resulting from the disease. These problems, particularly prevalent in poorer communities, receive little attention from international diabetes organizations. So far, the World Diabetes Foundation has funded 253 projects in developing countries, and paved the way for improved access to diabetes care and screening. Already, its efforts have inspired Uganda, Tanzania, and Kenya to include chronic diabetes care in their national health policies. COMMUNITY OUTREACH Socially responsible companies sometimes tackle a community problem near one of their facilities. Pioneer Hi-Bred’s Thailand team discovered that students in several provinces received inadequate nutrition from their school lunch programs because of insufficient funds. At that time, only US$0.56 per day was needed to feed a child well. In 2002, Pioneer Thailand formed an innovative collaboration among schools, communities, and local businesses to improve students’ nourishment. Pioneer donated high-yielding hybrid corn seed, supplies, and supervision; schools provided land; and each community contributed labor to raise a corn crop. After each harvest, the schools used proceeds from crop sales to fund healthier lunches. Local farmers, gaining valuable experience with seed technology and agricultural practices, began improving regional corn production. Entering its tenth year, Pioneer Hi-Bred’s “Corn for Student Lunch Program,” involving 14,000 people, has estimated revenues exceeding US$330,000, which is shared among all 43 participating schools. “We just received an award in Dar es Salaam from the president of Tanzania,” reports Genzyme’s Smith. “It’s for HAND (Humanitarian Assistance for Neglected Diseases), our malaria research program that looks for new drugs,” he explains. In collaboration with the Broad Institute of Harvard and the Massachusetts Institute of Technology, Genzyme’s focus in Africa is on screening for malaria, on-site. “During the sales meetings that are held in various U.S. locations, Novo Nordisk gets in touch with local communities to see what we can do to help them,” says Chinn. “We’ve built bikes for kids with diabetes. I’ve personally put together ‘care packages’ for the homeless in cities we’ve visited. We’re not just delivering a medication, we believe we have to be part of the community.” Some employers have to match social responsibility activities with their available resources. “We don’t have deep pockets, or a foundation,” notes Regeneron‘s Grossman. “We’re not yet profitable— we’re small but fast-growing, with one approved product. We mobilize our employees to become involved in ‘give-back’ programs in local communities.” Vertex Pharmaceuticals has a similar perspective. “We probably sold the first thing in our company’s history two weeks ago,” jokes Kelly-Croswell, “so we’re mostly giving of our time.” The company’s online community network encourages anyone involved with a local organization (professionally or privately) to post and ask for volunteers. In 2009, Vertex’s founder stepped down after 20 years. “As our parting gift, instead of a trophy, we announced the annual company-wide Joshua Boger Day of Service in his honor. All six global locations have coordinated service opportunities on the same day,” Kelly-Croswell notes. Near their Cambridge, Massachusetts headquarters, the company’s largest site, employees choose from 15 events, ranging from zoo projects to assembling care packages for military personnel to Habitat for Humanity projects. In 2009, about 800 employees took part. In 2010, the 1,100 Joshua Boger Day participants included a team of 15 scientists from the San Diego site. They presented “A Day in the Life of a Scientist/Engineer” to middle- and high-school students throughout the city’s school districts. Genzyme, another Cambridge, Massachusetts-based company, has always had community outreach programs. “We do things like Earth Day initiatives, bike rides for cancer, and walks for the March of Dimes,” says Smith. “They’re very popular with the staff, because they feel like they’re giving back. It’s surprising how important that kind of activity is to generating the right atmosphere around a place.” Genentech’s Chan praises his employer for its significant philanthropic work on behalf of patients. The Genentech Foundation, established in 2002, provides financial support to carefully chosen local and national not-for-profit patient education and advocacy efforts in the United States. The grants are intended for projects that enhance patients’ understanding of their disease, provide support through diagnosis and treatment, and improve their ability to obtain appropriate health care for a serious illness. Recent contributions have focused on support and education programs for patients with cancer or with a diagnosed immunological disorder. Grant recipients include the Children’s Cancer Association, the Multiple Sclerosis Association of America, Guide Dogs 8 for the Blind, the Jack & Jill Late-Stage Cancer Foundation, and the Lupus Foundation of America. Genentech’s Varney “is very conscious of publishing our work. That’s not only good for our science from a reputation perspective, but it’s part of moving science forward in the world. Most companies keep a lot of their work as trade secrets. Genentech has more publications than any other pharmaceutical company.” Noting the high quality of the journals where their research appears, he adds, “We feel publishing our work serves the advancement of the science.” At its sprawling South San Francisco headquarters, with nearly 50 buildings and 9,000 employees, Genentech encourages employee use of public transportation with an on-campus bus system. A fleet of free company buses transports employees throughout the Bay Area, so staff members don’t have to use their cars. ENCOURAGING FUTURE SCIENTISTS Cultivating future scientists is extremely popular among top employers. “Our company leaders are scientists who take science education seriously, no matter what size we’re at,” declares Regeneron’s Grossman. “We have 75 high-school and college interns,” says Grossman, “and we’ve come fullcircle. One of our high-school interns now is a patient who suffers from the condition that our first drug treats.” For Vertex’s STEM (Science, Technology, Engineering, and Mathematics) Initiative, staff scientists volunteer in local schools and engage kids in activities that foster their enthusiasm for science. The company collaborates with the local United Way to bring six-to-ten-year-olds to Vertex for hands-on science exploration, like visiting the formulation labs to learn how a pill is made. “Throughout the day, the kids have a chance to communicate with all sorts of scientists,” says Mueller. “These types of programs are mission-critical. Unfortunately, in our society the science and technology track is no longer the most wanted. We have to engage kids when they’re young so that science becomes understandable to them and fun. As a company, but also as a society, we need to nurture that.” Carol Milano is an independent journalist in New York City, covering health care and science. 10.1126/science.opms.r1100109 Published in advance of print on September 16, 2011. Print Edition available on October 7. To hear the Top Employers Podcast go to www.sciencecareers.org/TopEmployers2011 Upcoming Features Top Employers Survey (print edition) - October 7 Focus on Europe - October 21 Neuroscience: Emerging Fields - November 4 9
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