Screening and Assessing Steps to take before you immunize In this section: critical steps for appropriately assessing your patient’s immunization needs and the tools to complete those steps! Overview of this section: Assessing the need for immunizations assures no Best Practices Checklist: Screening and Assessing Five Steps to Take Before You Immunize yy Step 1: Get an immunization history yy Step 2: Determine vaccines needed opportunity is missed to give all vaccines that are due. yy Step 3: Screen for contraindications and precautions yy Step 4: Provide vaccine risk-benefit education yy Step 5: Assess future immunization needs Key Resources for Screening and Assessing Who to Call Centers for Disease Control and Prevention 800-232-4636 Minnesota Immunization Program For Minnesota specific issues (e.g. Minnesota school law) 800-657-3970 651-201-5503 July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 53 Best Practices Checklist: Screening and Assessing The information in this checklist will be covered in more detail throughout this section. clinician (e.g., in the waiting room or exam room). Get an immunization history In advance of patient visits, we review immunization records and flag charts of patients who are due or overdue. We’ve trained our immunization staff to know how to determine valid and invalid contraindications to vaccinations. When providing reminder calls we ask patients or parents to bring their immunization records. We use MIIC to help identify vaccination needs. We follow true contraindications and dispel common misconceptions among staff and patients. Each time a patient comes in, we routinely ask to see their immunization record to determine if they received vaccinations elsewhere. We use all patient encounters (including acutecare and follow-up visits) to assess and provide vaccinations. If we can't locate any records of previous vaccinations, we treat the patient as unvaccinated and give vaccinations that are recommended or required for school, child care, or work. Provide vaccine risk-benefit education We have the patient/parent sign a release of records to obtain immunization records from other clinics. We give patients/parents Vaccine Information Statements (VISs) to read and offer a copy to take home for each vaccine. If they need a VIS in another language, we provide it, if it is available. Determine vaccines needed We post and refer to the current immunization schedule for children, adolescents, and/or adults in order to provide all recommended vaccines. We use the “catch-up” schedule to bring children up to date on their vaccinations when they have fallen behind. We’ve trained our staff (e.g., receptionist, scheduler) to know how to determine the minimum ages and/or intervals permissible between vaccinations. This helps ensure that we miss no opportunity to vaccinate. We are familiar with special vaccination recommendations for high-risk patients (e.g., special groups who need hepatitis A, hepatitis B, pneumococcal, and meningococcal vaccines). We take the time to answer patients’ questions on vaccines and provide resources to those who have questions, concerns, or want more information. Assess future vaccination needs We inform the patient/parent when the next appointment for vaccinations is due. We set up the next immunization appointment and give the patient an appointment card before they leave the clinic. If we are unable to schedule an appointment we put the information in an electronic recall system or manual tickler system. When scheduling appointments, we remind patients/parents to bring along their (or their child’s) personal immunization record. We also confirm the address and phone number in case we need to contact them. Screen for contraindications and precautions We ask patients/parents to complete a screening questionnaire for contraindications and precautions to determine if the vaccinations they need can be given safely on the day of their visit. To save time, we have them complete it prior to seeing the 54 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Step 1: Get an immunization history Review the patient's immunization record at every visit. Whether you use paper or electronic records, make sure you have a system for viewing, reviewing, and flagging patient records for immunizations that are due or overdue. yy Paper medical records ○○ Place the immunization record in the front inside cover of the patient’s medical chart so it can be checked at every visit. ○○ Flag the record if the patient is behind on recommended immunizations. ○○ Make a note of which immunizations are due or overdue. yy Minnesota Immunization Information Connection (MIIC) ○○ View online or print a copy of the patient’s immunization record prior to the visit or when the patient checks in. Five Steps to Take Before You Immunize Don't miss an opportunity! Check the immunization history of ALL patients at every visit. ○○ Review MIIC's predictions to see which immunizations are due or overdue. yy Electronic medical records (EHR) ○○ View online or print a copy of the patient’s immunization record prior to the visit or when the patient checks in. ○○ Review the EHR's alert system to see which immunizations are due or overdue. Can't find an immunization record? Don’t just take your patient’s word for what shots he or she has had. You need a written record of which vaccines the patient has received and when (including the month, year, and preferably the day). Getting an immunization history helps assure that patients receive needed vaccines at the right minimum intervals and are not over-vaccinated. Where to look for patient immunization records yy An immunization registry, such as the Minnesota Immunization Information Connection (MIIC). Immunization registries have been growing since the 1990s and may have at least partial immunization records - especially for patients born since 1995. yy Clinics. Check with all health care providers where shots may have been given, including neighborhood clinics and local public health departments. yy Family records. Family or personal records such as baby books may contain immunization records (e.g., the Minnesota "Gold Card"). yy Schools or child care providers. Child care providers and schools must verify immunizations for attendees and may be able to look up records. yy Military records. Military records may be a source of immunization information for those who have served in the military. yy U.S. Citizenship and Immigration Services (USCIS) health records. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 55 Five Steps to Take Before You Immunize: Step 1 Whose records aren't in MIIC? MIIC only began in 2000, so unless clinics/providers have entered past immunization records, most likely MIIC won't have immunization records for persons: yy Who received their shots in another state yy Who Were born before 1995 yy Whose clinic/provider doesn't participate in MIIC yy Who haven't received any shots Tell patients to call the MIIC Help Desk at 651-201-5503 or 800-657-3970 to find out if their immunization records exist in MIIC. TAKE ACTION If you can’t find a patient’s record anywhere: 1. Consider the patient unvaccinated. 2. Administer shots today that are required for school, child care, or work. 3. Schedule a follow-up appointment and continue to look for records before the patient’s next clinic visit. 4. Obtain a signed release of information form from the patient or parent/ guardian if you need to request immunization records from another state's clinic or immunization registry. 5. Once you have received an immunization history, update the clinic record and MIIC and follow up with the patient or parent/guardian. 56 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Five Steps to Take Before You Immunize: Step 2 Step 2: Determine vaccines needed Use the following resources and guidelines to assess for needed vaccines. Don't assume your patient only needs routine vaccines recommended for his or her age. Check vaccine needs based on risk factors such as occupation, medical condition, or social behavior, and give all the vaccines the patient needs. Patients may need vaccines more frequently, sooner, or in a different dosage than routinely recommended. AGE Infants, children, and adolescents ○ Recommended Immunization Schedule for Children and Adolescents, Minnesota, MDH (pages 73-75) ○ Summary of Recommendations for Child/Teen Immunization, IAC (pages 81-84) ○ Perinatal Hepatitis B Prevention Pocket Guide, MDH (page 89) Adults ○ Do I Need Any Vaccinations Today? IAC (pages 71-72) ○ Recommended Adult Immunization Schedule, Minnesota, MDH (pages 77-79) ○ Summary of Recommendations for Adult Immunization, IAC (pages 85-88) ○ Is your patient behind on their immunizations? Make sure to follow the catchup schedule and minimum intervals for their age. Pneumococcal Vaccination Pocket Guide, MDH (page 90) All ages ACIP’s General Recommendations on Immunization: ○ Table 1. Recommended and minimum ages and intervals between vaccine doses (pages 94-95) ○ ○ ○ Table 3. Guidelines for spacing of live and inactivated antigens (page 96) Table 4. Guidelines for administering antibody-containing products and vaccines (page 96) Table 5. Recommended intervals between administration of antibodycontaining products and measles- or varicella-containing vaccine, by product and indication for vaccination (page 97) FOREIGN-BORN Immunization recommendations for foreign-born persons living in Minnesota are the same as for anyone born in the United States. Follow these general rules: Vaccines administered outside of the U.S., including products not used in the U.S., are considered valid if they meet the minimum age and interval requirements. If no written documentation exists, consider the patient unvaccinated. Vaccinate/revaccinate by giving age-appropriate vaccinations the same as for anyone born in the U.S. Use the catch-up schedule to get patients up to date. Serologic testing is not routinely recommended; however it can help determine which vaccinations are needed in some situations. Serologic testing isn't available for all vaccines and isn't a guarantee of protection against infection; see page 58 for resources. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 57 Five Steps to Take Before You Immunize: Step 2 How many times have you looked at a new patient’s immunization record and said, "I have no idea what this means?" Some patients' immunization records may have foreign vaccine terms listed on them. See pages 111-130 for resources to help you translate foreign vaccine terms. Children adopted internationally may have unreliable immunization records and revaccination may be necessary. Alternatively, serologic testing may be used to determine vaccines needed. For more on vaccine recommendations and serologic testing for foreign-born persons, see: ○ ACIP’s General Recommendations on Immunization: Table 14. Approaches to evaluation and vaccination of persons vaccinated outside the United States who have no (or questionable) vaccination records (page 99) ○ ○ ○ ACIP’s General Recommendations on Immunization: Table 1. Recommended and minimum ages and intervals between vaccine doses (pages 94-95) Recommended Immunization Schedule for Children and Adolescents, Minnesota, MDH (pages 73-75) Recommended Adult Immunization Schedule, Minnesota, MDH (pages 77-79) For translation of foreign vaccine terms and vaccine products, see: ○ Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages, IAC (pages 111-112) ○ Disease, Vaccine and Related Terms, CDC (pages 113-118) ○ Trade Names, CDC (pages 119-129) IMMUNIZATION LAWS Immunization laws protect everyone, because high immunization levels prevent disease outbreaks. Minnesota has various laws requiring immunizations for children and adults enrolled in child care, school, and college settings. Legal exemptions are allowed - both for medical reasons and conscientiously held beliefs. Provider's Quick Reference on Minnesota's Immunization Laws, MDH (pages 133-134) MEDICAL CONDITION It may be helpful to review all of the vaccines that may be indicated, recommended, or contraindicated because of the patient's medical condition. The following resources included in this guide can help. Immunocompromised ○ ACIP’s General Recommendations on Immunization: Table 13. Vaccination of persons with primary and secondary immunodeficiencies (page 98) ○ 58 www.health.state.mn.us/immunize Summary of ACIP Recommendations on Use of Immune Globulins, MDH (page 104) Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Five Steps to Take Before You Immunize: Step 2 Medical and other indications ○ Do I Need Any Vaccinations Today? IAC (pages 71-72) ○ Recommended Adult Immunization Schedule, Minnesota, MDH (pages 77-79) ○ Vaccines Indicated for Infants, Children, and Adolescents Based on Medical and Other Indications, MDH (pages 105-107) Pregnant women ○ Pregnancy and Vaccination pocket guide, MDH (page 91) ○ Recommended Adult Immunization Schedule, Minnesota, MDH (pages 77-79) ○ Guidelines for Vaccinating Pregnant Women, CDC Not included in this guide but available on the web at www.cdc.gov/ vaccines/pubs/preg-guide.htm Premature infants Immunize premature infants according to the child's chronologic age. Hepatitis B is an exception in some cases. ○ Recommended Immunization Schedule for Children and Adolescents, Minnesota, MDH (pages 73-75) ○ Perinatal Hepatitis B Prevention Pocket Guide, MDH (page 89) ○ Vaccines Indicated for Infants, Children, and Adolescents Based on Medical and Other Indications, MDH (pages 107-103) OCCUPATION Some occupations require certain immunizations. To help determine what immunizations might be needed, review the following references. Health care workers ○ Recommended Adult Immunization Schedule, Minnesota, MDH (pages 77-79) ○ Healthcare Personnel Vaccination Recommendations, IAC (page 109) Other occupations that may place patients at risk ○ Vaccines Indicated by Occupation, MDH (pages 105-107) ACIP recommendations Not included in this guide but available on the web at www.cdc.gov/vaccines/ pubs/ACIP-list.htm: ○ Immunization of Health-Care Workers: Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the Hospital Infection Control Practices Advisory Committee (HICPAC), MMWR, December 26, 1997 / 46(RR-18);1-42. ○ Influenza Vaccination of Health-Care Personnel: Recommendations of the Healthcare Infection Control Practices Advisory Committee (HICPAC) and the Advisory Committee on Immunization Practices (ACIP), MMWR, February 24, 2006 / 55(RR02);1-16. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 59 Five Steps to Take Before You Immunize: Step 2 TRAVEL If your patient is traveling out of the country they may need immunizations specific to their destination. For a comprehensive review of immunizations needed as well as disease prevention strategies, refer patients to an international travel health clinic. These clinics provide a variety of pre- and post-travel services and are authorized by the Minnesota Department of Health to administer yellow fever vaccine. International travelers ○ Vaccines for the International Traveler: Plan Ahead for Your Travel Shots, MDH; includes a list of international travel clinics in Minnesota (pages 130132) ○ Health Information for International Travel (Yellow Book), CDC Not included in this guide but available on the web at www.cdc.gov/travel/ index.htm SOCIAL BEHAVIOR Additional immunizations may be recommended based on your patients' social behavior (e.g., sexual activity, sexual orientation, recreational drug use). ○ ○ Do I Need Any Vaccinations Today? IAC (pages 71-72) Recommended Adult Immunization Schedule footnotes, Minnesota, MDH (page 78) ACIP recommendations Not included in this guide but available on the web at www.cdc.gov/vaccines/ pubs/ACIP-list.htm: ○ Prevention of Hepatitis A Through Active or Passive Immunization ○ A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States - 60 www.health.state.mn.us/immunize Part I: Immunization of Infants, Children, and Adolescents Part II: Immunization of Adults ○ Bivalent Human Papillomavirus Vaccine (HPV2, Cervarix) for Use in Females and Updated HPV Vaccination Recommendations from the ACIP ○ Quadrivalent Human Papillomavirus Vaccine (HPV4, Gardasil) for Use in Males and Guidance from the ACIP Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Five Steps to Take Before You Immunize: Step 3 Step 3: Screen for contraindications and precautions Don't miss opportunities to vaccinate because of misconceptions about a contraindication or precaution. Be aware of all possible contraindications or precautions for health conditions that might preclude giving a particular vaccine. See the Guide to Contraindications and Precautions to Commonly Used Vaccines on pages 135138. Remember to screen patients each time you vaccinate because responses to the questions may change. See the Immunization Action Coalition's Screening Checklist for Contraindications to Vaccines for Children and Teens and Screening Checklist for Contraindications to Vaccines for Adults on pages 139-142. What is a contraindication? A contraindication to a vaccine is a condition in a patient that greatly increases the chance of a serious adverse reaction. Generally, vaccines should not be given if someone has a contraindication. What is a precaution? A precaution is a condition in a patient that may either increase the chance of a serious adverse reaction to a vaccine or compromise the ability of the vaccine to produce immunity. Generally, when a precaution exists, vaccines should be deferred. When to give a vaccine despite a precaution: In general, when a permanent or temporary precaution exists, vaccine should be deferred. However, there may be situations when the benefit of vaccination outweighs the risk, and the provider may choose to give the vaccine. For example, prolonged crying or a high fever after a dose of pertussis-containing vaccine is considered a precaution to giving subsequent doses of pertussis vaccine to a child. But, if the child is at high risk of pertussis infection (e.g., during a pertussis outbreak in the community), a provider may choose to vaccinate the child and treat the adverse reaction if it occurs. Screening for contraindications and precautions prevents unnecessary adverse events. Local allergic reaction: Itching or swelling localized to the vaccination site Usually not a contraindication to vaccination A severe allergic reaction (e.g., anaphylaxis) is the sudden or gradual onset of: Generalized itching, redness, or hives Swelling of the lips, face, or throat Bronchospasms (wheezing) Shortness of breath Shock Cardiovascular collapse These are NOT contraindications or precautions for administering any vaccines. Give vaccines. Mild acute illness with or without fever Mild to moderate local reaction (swelling, redness, soreness); fever less than 105°F or 40.5°C after prior dose Lack of prior physical examination in well-appearing person On antibiotics Convalescent phase of illness Premature birth (hepatitis B vaccine is an exception in certain circumstances; see Perinatal Hepatitis B Prevention Pocket Guide, page 89) Recent exposure to an infectious disease Allergy to substances not in the vaccine July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 61 Five Steps to Take Before You Immunize: Step 4 Step 4: Provide vaccine risk-benefit education Risk-benefit education comes in two main forms: giving patients/parents the legally required Vaccine Information Statements (VISs) and talking with them about any concerns they may have. Reminder All patients, including adults, must be given VISs before they get their shots. Use the VIS as an opportunity to talk about vaccine safety issues. Give Vaccine Information Statements (VISs) Federal law (National Childhood Vaccine Injury Act of 1986,42 U.S.C. §300aa-26) requires that VISs be provided to the vaccine recipient (including adult vaccinees) each time vaccinations are administered. This applies to each dose in a multidose series. VISs are required for all recommended childhood and adult vaccines. Additional VISs are available for vaccines not routinely recommended. For more information on VISs see the table Give Vaccine Information Statements (VISs) on page 63 and Instructions for the Use of Vaccine Information Statements on page 143. Encourage patients/parents to carefully read the VISs you give them before receiving the vaccination. The VIS answers questions like: What shots is my child getting today? What diseases are the shots preventing? What are the possible side effects? Is there any reason not to give the shot today? What do I do if a side effect occurs? When do I bring my child back for more shots? In addition to VISs, be sure to have other resources on hand to address patients' concerns; see Reliable Sources on Immunization Information on pages 145-146. 62 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Five Steps to Take Before You Immunize: Step 4 Give Vaccine Information Statements (VISs) What is a VIS? A vaccine information statement (VIS) is an information sheet, produced by CDC, informing vaccine recipients, or their parents or legal guardians, of the benefits and risks of a vaccine. When must a VIS be given? Federal law requires VISs to be given before administering each dose of all recommended vaccines. Note: A Multi-Vaccine VIS is as an optional alternative when two or more routine childhood vaccines (i.e., DTaP, hepatitis B, Hib, pneumococcal, polio, or rotavirus) are administered at the same visit. To whom must a VIS be given? yy The parent or legal guardian of any child to whom the provider intends to administer the vaccine, or yy The adult to whom the provider intends to administer vaccine. How must a VIS be provided? yy Offer a copy to read during the immunization visit and before administering vaccine: ○○Patients may read the VISs as a paper copy, on an office computer, or as a permanent laminated copy. yy Offer a copy to take home with them (however they aren't required to take it with them): ○○Patients may take a paper copy, or if they prefer to download the VIS onto a mobile device, direct them to CDC's patient VIS download webpage during the visit, www.cdc.gov/vaccines/pubs/vis/vis-downloads.htm. Is a parent/patient signature required to acknowledge receiving a VIS? yy No state or federal law requires the signature of the adult patient or of the parent/guardian of a minor child to acknowledge receipt of a VIS. Where can you obtain reproducible copies of VISs? yy Download them from www.immunize.org/vis/ yy Call CDC-INFO at 800-CDC-INFO or 800-232-4636. yy Call the Minnesota Immunization Program at 651-2015503 or 800-657-3970. What VISs translations are available? VISs are available in more than 40 languages. For the most current versions, see www.immunize.org/vis/ Is documentation that we provided a VIS necessary? It is required. The provider must document both the date of the VIS (found at the bottom of the back page) and the date the VIS was given to the patient or parent/guardian. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 63 Five Steps to Take Before You Immunize: Step 4 Discuss vaccine safety concerns Providing patients -- especially parents -- with risk-benefit education is more important than ever. As a result of our immunization success and low levels of vaccinepreventable diseases, some parents fear vaccines more than the diseases they prevent. We need to address these concerns in order to keep immunization rates high. If we don't, diseases like measles and polio that still circulate in many parts of the world can return and cause outbreaks in the U.S. Common parent concerns Parents depend on you to be knowledgeable and to reassure them that vaccines are safe. To do that, you need to know what their common concerns are. Recent CDC focus groups identified these issues: yy Parents want and need to discuss vaccine safety issues. They resent having their concerns dismissed. yy Parents and patients identify their health care provider as their most trusted source of immunization information. yy Until a provider establishes rapport with them, parents do not want to hear about the science of immunization. yy Parents do not want to hear overblown claims (e.g., that vaccines are 100 percent safe and 100 percent effective). Using such claims comes across as defensive and uninformed. That said, it is important to acknowledge that vaccines are very safe and effective. yy Parents only have the health and safety of their child in mind and often have dutifully explored information about immunizations. Providers, who also have the health of the child as a key goal of care, can take advantage of this common value. 64 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Five Steps to Take Before You Immunize: Step 4 Responding to vaccine-hesitant parents using the "CASE" framework Alison Singer of the Autism Science Foundation has developed a framework called CASE for responding to vaccine-hesitant parents. It suggests a sequential discussion process based on focus group findings. The following information is provided courtesy of Alison Singer. Making the CASE for Vaccines Corroborate Acknowledge the parent's concern and find some point on which you can agree. Set the tone for a respectful, successful talk. About Me Describe what you have done to build your knowledge base and expertise. Science Describe what the science says. Explain/Advise Give advice to the patient, based on the science. "I want to spread out the shots so they won't overwhelm my child's immune system." C:Kids today certainly get more shots than kids did years ago. A:Our practice follows the CDC schedule because it is carefully designed to protect children at the time they are most vulnerable to disease. I recently returned from a meeting...or I served on a committee that reviewed the schedule... S:Although kids get more shots today, they actually receive fewer antigens than when they got fewer shots, because technology has enabled us to make vaccines that have only the part of the cell that induces immune response. Plus, the immunological challenge from a vaccine is nothing compared to what kids fight off everyday. An ear infection is a bigger immunological challenge. Immunizations are a "drop in the ocean" compared to what kids fight off everyday. E:We want all the kids in our practice to be immunized on time so that they have the greatest chance for a long, healthy life. Anything less is substandard care. I don't want that for your child. As hard as it was to see my own children get a lot of shots, I knew it was important. My own children are fully vaccinated. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 65 "I heard on TV that vaccines cause autism." C:There's certainly been a lot of television coverage about vaccines and autism so I can understand why you have questions. A: .I always want to make sure I'm up to date on the latest information so that I can do what's best for my patients. So I've researched this thoroughly. In fact, I just returned from a professional conference... S:The scientific evidence does not support a link between vaccines and autism. Several professional organizations and respected scientists from the CDC, AAP, NIH, IOM (etc.) all reviewed the studies that have been conducted and reached the same conclusion. Dozens of studies have been done. None show a link. In fact, the latest autism science indicates... E: .Vaccines are critical to maintaining health and well-being. They prevent diseases that cause real harm. Choosing not to vaccinate does not protect children from autism, but it does leave them open to diseases. Kids need these vaccines. "Measles isn't so bad; I had it and I was fine." C:I can understand why you might feel that way. We just don't hear much about how serious it can be. A: .The vaccine program has been so successful and a lot of the diseases that we feared, like polio and measles, are no longer a concern. Until last year, I had never seen a case of Hib or measles, but now these diseases are making a comeback. In my practice... S:These diseases have come back in areas where vaccination rates are low. For example, in 2010 five children died of Hib and 10 babies died of pertussis in California. In Minnesota in 2011 almost half the children who got measles were hospitalized. They have to be very sick for that to happen. E: We care about our patients and don't want to see your child or any others I care for be hospitalized for a disease that can easily be prevented. 66 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Step 5: Assess future immunization needs Help make sure patients get their next immunizations on time. yy Before they leave the clinic, assess patients’ future immunization needs and schedule the next appointment! Give them an appointment reminder card. yy Use MIIC to help determine which immunizations are due and when. yy Make certain that you observe the minimum interval necessary between doses, see Table 1: Recommended and minimum ages and intervals between vaccine doses on pages 94-95. Use MIIC or the tools in your EHR to create lists of patients whose immunizations are overdue and generate recall notices or labels. yy Be sure each patient leaves with an updated personal immunization record such as the MIIC record or the Minnesota Immunization Record (“Gold Card”). July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 67 68 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 For Determining Vaccines Needed Key Resources for General Immunization Recommendations Screening and Do I Need Any Vaccinations Today? (IAC) Screening questionnaire for adult patients to help assess what shots they may need: Assessing www.immunize.org/catg.d/p4036.pdf Recommended Immunization Schedules, Minnesota (MDH) Minnesota vaccination schedule for adults and children and adolescents, including catch-up schedules: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html Summary of Recommendations (IAC) Reference table on appropriate use, scheduling, and contraindications of childhood and adult vaccines: www.immunize.org/catg.d/p2010.pdf (childh/teen) www.immunize.org/catg.d/p2011.pdf (adult) Specific Populations - Immunization Recommendations Haven’t got time to read through a 54-page ACIP statement? These resources pull together often-used information for easy access. As always, if you need more details or don’t find an answer for your particular situation, you can call the CDC at 800-232-4636. July 2011, Minnesota Department of Health ACIP’s General Recommendations on Immunization: Table 1: Recommended and minimum ages and intervals between vaccine doses Table 3: Guidelines for spacing of live and inactivated antigens Table 4: Guidelines for administering antibody-containing products and vaccines Table 5: Recommended intervals between administration of antibodycontaining products and measles- or varicella-containing vaccine, by product and indication for vaccination Table 13: Vaccination of persons with primary and secondary immunodeficiencies Table 14:Approaches to evaluation and vaccination of persons vaccinated outside the United States who have no (or questionable) vaccination records: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf Perinatal Hepatitis B Prevention Pocket Guide (MDH) Guide to recommended strategies to prevent perinatal transmission of hepatitis B including the vaccine schedule for infants born to HBsAg positive mothers: www.health.state.mn.us/divs/idepc/diseases/hepb/perinatal/hcp.html Pneumococcal Vaccination Pocket Guide (MDH) Guide to assist health care providers to determine who should receive a pneumococcal vaccination: www.health.state.mn.us/divs/idepc/diseases/pneumococcal/hcp/pocket.html Pregnancy and Vaccination Pocket Guide (MDH) Guide to assist health care providers with vaccinating pregnant women, page 91 Summary tables of ACIP recommendations on: ○ Vaccines Indicated for Infants, Children, and Adolescents Based on Medical and Other Indications, page 101-103 ○ Use of Immune Globulins, page 104 ○ Vaccines Indicated by Occupation, page 105-107 Healthcare Personnel Vaccination Recommendations (IAC) Vaccine specific recommendations for health care workers: www.immunize.org/catg.d/p2017.pdf Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 69 Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages (IAC) Table to help providers interpret English disease names into Eastern and Western European languages: www.immunize.org/catg.d/p5122.pdf Disease, Vaccine and Related Terms (CDC) Table to help providers interpret vaccination records from other countries and for translating vaccine-related terms www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/foreignproducts-tables.pdf Trade Names (CDC) Table lists many vaccine products that are (or have been) used in the U.S. and in international markets: www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/foreignproducts-tables.pdf Plan Ahead for Your Travel Shots (MDH) Tips to planning ahead for international travel: www.health.state.mn.us/divs/idepc/immunize/travel/travelshots.pdf Minnesota Immunization Laws Provider's Quick Reference on Minnesota's Immunization Laws (MDH) Quick reference guide for health care providers, child care, and school personnel on Minnesota's immunization laws: www.health.state.mn.us/divs/idepc/immunize/laws/qreflaws.html For Screening for Contraindications and Precautions Guide to Contraindications and Precautions to Commonly Used Vaccines (MDH) Guide to help providers determine what symptoms and conditions contraindicate vaccination: www.health.state.mn.us/divs/idepc/immunize/hcp/vaccine.html Screening Checklist for Contraindications (IAC) Form patients fill out to help you evaluate which vaccines can be given at that day's visit; reverse side includes information for professionals: www.immunize.org/catg.d/p4060.pdf (child and teen) www.immunize.org/catg.d/p4065.pdf (adult) For Providing Risk-Benefit Education 70 www.health.state.mn.us/immunize Instructions for the Use of Vaccine Information Statements (CDC) Information sheet on the use of VISs, including recordkeeping requirements: www.cdc.gov/vaccines/pubs/vis/downloads/vis-Instructions.pdf Reliable Sources of Immunization Information (MDH) Where to go for accurate and up-to-date information on vaccines and vaccine safety; includes web sites, phone numbers, and publications: www.health.state.mn.us/divs/idepc/immunize/safety/imminfo.pdf Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Your name: ____________________________________ Ê>ÌiÊvÊLÀÌ \ÚÚÚÚÉÚÚÚÚÉÚÚÚÚToday’s date:ÊÚÚÚÚÉÚÚÚÚÉÚÚÚÚ (mo.) (day) ; (yr.) (mo.) (day) (yr.) 'R,1HHG$Q\9DFFLQDWLRQV7RGD\" Many adults are behind on their vaccinations. This questionnaire will help you and your healthcare provider determine if you need any vaccinations today. Please check the boxes that apply to you. ,QÁXHQ]DYDFFLQDWLRQ I haven’t had my annual influenza vaccination yet this season — so I need it now. 3QHXPRFRFFDOYDFFLQDWLRQ33693&9 I am age 65 or older, and I have never had a pneumococcal shot. I am age 65 or older and have had 1 or 2 doses of pneumococcal vaccine when I was younger than age 65; it has been 5 years or more since the last shot. I am younger than age 65, I have not been vaccinated against pneumococcal disease, and at least one of the following applies to me: Ê UÊI smoke cigarettes. Ê UÊI have heart, lung (including asthma), liver, kidney, or sickle cell disease; diabetes; or alcoholism. I am younger than age 65, I have or have not been vaccinated against pneumococcal disease, and at least one of the following applies to me: ÊÊ UÊÊ >ÛiÊ>ÊÜi>ii`ÊÕiÊÃÞÃÌiÊ`ÕiÊÌÊV>ViÀ]Ê`}½ÃÊ`Ãi>Ãi]ÊiÕi>]ÊÞ« >]ÊÕÌ«iÊÞi>]Ê`iÞÊv>ÕÀi]Ê6É-ÆÊ or I am receiving radiation therapy; or I am on medication that suppresses my immune system. UÊÊ >ÛiÊ >`Ê>ÊÀ}>ÊÀÊLiÊ>ÀÀÜÊÌÀ>ë>̰ Ê UÊÊ >ÛiÊ >`ÊÞÊëiiÊÀiÛi`]Ê >ÛiÊ >`ÊÀÊÜÊ >ÛiÊ>ÊVV i>ÀÊ«>Ì]ÊÀÊ >ÛiÊi>}Êë>ÊyÕ`° I live in a nursing home or other long-term care facility, and I have never had a pneumococcal shot. 7HWDQXVGLSKWKHULDDQGSHUWXVVLVZKRRSLQJFRXJKFRQWDLQLQJYDFFLQDWLRQHJ'73'7D3 7GDSRU7G I have not had a pertussis-containing vaccine (Tdap) as an adolescent or adult (this applies to pregnant women, too). I have not yet had at least 3 tetanus- and diphtheria-containing shots. ÊÊ >ÛiÊ >`Ê>ÌÊi>ÃÌÊÎÊÌiÌ>ÕÃÊ>`Ê`« Ì iÀ>VÌ>}Êà ÌÃÊÊÞÊviÌi]ÊLÕÌÊÊLiiÛiÊ̽ÃÊLiiÊ£äÊÞi>ÀÃÊÀÊÀiÊÃViÊÊÀiViÛi`ÊÞ last shot. I have no idea if I ever received any tetanus- and diphtheria-containing shots in school, the military, or elsewhere. 0HDVOHV0XPSV5XEHOOD005YDFFLQDWLRQ ÊÊÜ>ÃÊLÀÊÊ£xÇÊÀÊ>ÌiÀÊ>`ÊiÛiÀÊÀiViÛi`Ê>Ê,Êà ÌÊÀÊÊ`½ÌÊÜÊvÊÊÀiViÛi`Ê>Êà ̰ I am a woman thinking about a future pregnancy and do not know if I’m immune to rubella. ÊÊ>Ê>Ê i>Ì V>ÀiÊÜÀiÀ]ÊÊ`ÊÌÊ >ÛiÊ>Ê ÃÌÀÞÊvÊi>ÃiÃÊÀÊÕ«Ã]Ê>`ʽÛiÊ >`ÊÞÊiÊ`ÃiÊvÊ,ÊÛ>VVi° ÊÊÜ>ÃÊLÀÊÊ£xÇÊÀÊ>ÌiÀ]Ê>`ÊÊ>ÊVÕ`i`ÊÊiÊvÊÌ iÊvÜ}Ê}ÀÕ«ÃÊvÀÊÜ ÊÓÊ,Êà ÌÃÊ>ÀiÊÀiVi`i`]ÊLÕÌÊÊ >ÛiÊÀiViÛi`ÊÊ only 1 shot. UÊI am entering college or a post–high school educational institution. UÊI had a blood test that shows I do not have immunity to measles, mumps, or rubella. UÊI am planning to travel internationally. Human papillomavirus (HPV) vaccination I am a woman age 26 or younger and haven’t completed a series of shots against human papillomavirus. I am a man age 21 or younger and haven’t completed a 3-dose series of shots against human papillomavirus. I am a man age 22 through 26, I have not completed a 3-dose series of HPV vaccine, and at least 1 of the following applies to me: t I want to be protected from HPV. t I have a weakened immune system as a result of infection (including HIV), disease, or medications. t I have sex with men. (continued on page 2) I am older than age 26 and although I started the series when I was younger, I never completed it. /iV V>ÊVÌiÌÊÀiÛiÜi`ÊLÞÊÌ iÊ iÌiÀÃÊvÀÊÃi>ÃiÊ ÌÀÊ>`Ê*ÀiÛḭ ÜÜܰÕâi°À}ÉV>Ì}°`É«{äÎȰ«`vÊÊUÊÊÌiÊ*{äÎÈÊnÉ£Ó® Õâ>ÌÊVÌÊ >ÌÊÊUÊÊ£xÇÎÊ-iLÞÊÛi°ÊÊUÊÊ-̰Ê*>Õ]Ê Êxx£ä{ÊÊUÊÊÈx£®ÊÈ{ÇääÊÊUÊÊÜÜܰÛ>VVivÀ>̰À}ÊÊUÊÊÜÜܰÕâi°À} July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 71 'R,1HHG$Q\9DFFLQDWLRQV7RGD\"FRQWLQXHG 3DJH +HSDWLWLV$YDFFLQDWLRQ ÊÊÜ>ÌÊÌÊLiÊÛ>VV>Ìi`ÊÌÊ>Û`Ê}iÌÌ}Ê i«>ÌÌÃÊÊ>`ÊëÀi>`}ÊÌÊÌÊÌ iÀð ÊÊÜ>ÃÊÛ>VV>Ìi`ÊÜÌ Ê i«>ÌÌÃÊÊÛ>VViÊÊÌ iÊ«>ÃÌÊLÕÌÊiÛiÀÊÀiViÛi`ÊÌ iÊÃiV`Êà ̰ ÊÊ} ÌÊ >ÛiÊLiiÊiÝ«Ãi`ÊÌÊÌ iÊ i«>ÌÌÃÊÊÛÀÕÃÊÊÌ iÊ«>ÃÌÊÓÊÜiið ÊÊ>ÊÊiÊvÊÌ iÊvÜ}ÊÀÃÊ}ÀÕ«Ã]Ê>`ÊÊ >Ûi½ÌÊV«iÌi`ÊÌ iÊÓ`ÃiÊÃiÀiÃÊvÊ i«>ÌÌÃÊÊà ÌÃ\ UÊÊÌÀ>ÛiÊÀÊ«>ÊÌÊÌÀ>ÛiÊÊVÕÌÀiÃÊÜ iÀiÊ i«>ÌÌÃÊÊÃÊV°1,2 UÊÊÕÃiÊÃÌÀiiÌÊ`ÀÕ}Ã°Ê UÊÊ >ÛiÊÀÊÜÊ >Ûi®ÊVÌ>VÌÊÜÌ Ê>Ê>`«Ìi`ÊV `ÊÜÌ ÊÌ iÊwÀÃÌÊ UÊÊ >ÛiÊV ÀVÊÛiÀÊ`Ãi>Ãi° Ê ÈäÊ`>ÞÃÊvÊÌ iÀÊ>ÀÀÛ>ÊvÀÊ>ÊVÕÌÀÞÊÜ iÀiÊ i«>ÌÌÃÊÊÃÊV°2 UÊÊ >ÛiÊ>ÊVÌÌ}Êv>VÌÀÊ`ÃÀ`iÀ° UÊÊ>Ê>Ê>ÊÜ Ê >ÃÊÃiÝÊÜÌ Êi°Ê UÊÊÜÀÊÜÌ Ê6viVÌi`Ê«À>ÌiÃÊÀÊÜÌ Ê6ÊÊ>ÊÀiÃi>ÀV laboratory setting. +HSDWLWLV%YDFFLQDWLRQ I want to be vaccinated to avoid getting hepatitis B and spreading it to others. ÊÊ>Ê>}iÊ£nÊÀÊÞÕ}iÀÊ>`Ê >Ûi½ÌÊV«iÌi`ÊÌ iÊÃiÀiÃÊvÊ i«>ÌÌÃÊÊà Ìð I was vaccinated with hepatitis B vaccine in the past but never completed the full 3-dose series. I am in one of the following risk groups, and I haven’t completed the series of hepatitis B shots: UÊÊiVÌÊÃÌÀiiÌÊ`ÀÕ}ð UÊÊ>ÊÃiÝÕ>ÞÊ>VÌÛiÊ>`Ê>ÊÌÊÊ>Ê}ÌiÀ]ÊÕÌÕ>ÞÊ monogamous relationship. UÊÊ >ÛiÊV ÀVÊÛiÀÊ`Ãi>Ãi° UÊÊ>Ê>Ê>ÊÜ Ê >ÃÊÃiÝÊÜÌ Êi° UÊÊ>ÊÀÊÜÊLiÊÊ`iÞÊ`>ÞÃð UÊÊ>Ê>Ê}À>Ì]ÊÀÊÞÊ«>ÀiÌÃÊ>ÀiÊ}À>ÌÃ]ÊvÀÊ>Ê>Ài>Ê UÊÊ>ÊÞÕ}iÀÊÌ >Ê>}iÊÈäÊÞi>ÀÃÊ>`Ê >ÛiÊ`>LiÌið of the world where hepatitis B is common, so I need testing and UÊÊ>Ê>Ê i>Ì V>ÀiÊÀÊ«ÕLVÊÃ>viÌÞÊÜÀiÀÊÜ ÊÃÊiÝ«Ãi`ÊÌÊÊ may need vaccination.Î]{ blood or other body fluids. UÊÊÛiÊÜÌ ÊÀÊ>Ê>ÊÃiÝÊ«>ÀÌiÀÊvÊ>Ê«iÀÃÊÜÌ Ê i«>ÌÌÃÊ°Ê UÊÊ«ÀÛ`iÊ`ÀiVÌÊÃiÀÛViÃÊvÀÊ«i«iÊÜÌ Ê`iÛi«iÌ>Ê disabilities. UÊÊ >ÛiÊLiiÊ`>}Ãi`ÊÜÌ Ê>ÊÃiÝÕ>ÞÊÌÀ>ÃÌÌi`Ê`Ãi>Ãi° UÊÊÌÀ>ÛiÊÀÊ«>ÊÌÊÌÀ>ÛiÊÕÌÃ`iÊÌ iÊ1°-°1,3 UÊÊ >ÛiÊLiiÊ`>}Ãi`ÊÜÌ Ê6° &KLFNHQSR[YDULFHOODYDFFLQDWLRQ ÊÊÜ>ÃÊLÀÊÊ£näÊÀÊ>ÌiÀÊ>`Ê >ÛiÊiÛiÀÊ >`ÊV Vi«ÝÊÀÊÌ iÊÛ>VVi]ÊÀÊÊÕÃÌÊ`½ÌÊܰ ÊÊÜ>ÃÊLÀÊLivÀiÊ£näÊ>`Ê>ÊiÌ iÀÊ>Ê i>Ì V>ÀiÊÜÀiÀÊÀÊvÀi}ÊLÀ]Ê>`Ê>ÊÌÊÃÕÀiÊvʽÛiÊ >`ÊV Vi«ÝÊÀḚ̂ I have received 1 dose of varicella vaccine in the past, but never got a second shot. 0HQLQJRFRFFDOYDFFLQDWLRQ ÊÊ>Ê>}iÊ£nÊÀÊÞÕ}iÀÊ>`Ê >Ûi½ÌÊÀiViÛi`Ê>Êi}VVV>Êà ̰ I am age 21 or younger and am (or will be) in college, living in a residence hall, and haven’t had a meningococcal shot since my 16th birthday. I am traveling to an area of the world where meningococcal disease is common.1 ÊÊ >ÛiÊÃViÊViÊ`Ãi>Ãi]ÊÀÊÞÊëiiÊýÌÊÜÀ}ÊÀÊ >ÃÊLiiÊÀiÛi`]ÊÀÊÊ >ÛiÊ>Ê«iÀÃÃÌiÌÊV«iiÌÊV«iÌÊ`iwViVÞ° I am a microbiologist routinely exposed to isolates of Neisseria meningitidis. ÊÜ>ÃÊ«ÀiÛÕÃÞÊÛ>VV>Ìi`ÊxÊÀÊÀiÊÞi>ÀÃÊ>}Ê>`ÊVÌÕiÊÌÊLiÊ>ÌÊÀÃÊvÀÊi}VVV>Ê`Ãi>Ãi°Ê Ìi\ÊÌ ÃÊ`iÃÊÌÊ>««ÞÊÌÊÃÌÕ`iÌÃÊÊ whose only risk factor is attending college. 6KLQJOHV]RVWHUYDFFLQDWLRQ Ê>Ê>Ê>`ÕÌÊ>}iÊÈäÊÀÊ`iÀÊ>`Ê >Ûi½ÌÊ >`Ê>Êà }iÃÊà ̰ 1RWHÊ`ÕÌÃÊÜ ÊÌÀ>ÛiÊ>ÞÊii`Ê>``Ì>ÊÛ>VV>ÌÃ]ÊÃÕV Ê>ÃÊ«ÊÀÊÌ iÀðÊ/>ÊÌÊÞÕÀÊ i>Ì V>ÀiÊ«ÀÛ`iÀ° )RRWQRWHV £°Ê >ÊÞÕÀÊV>ÊÌÀ>ÛiÊVVÊÌÊw`ÊÕÌÊvÊ>``Ì>ÊÛ>VViÃÊ>ÀiÊÀiVi`i`° Ó°Ê ÕÌÀiÃÊÜ iÀiÊ i«>ÌÌÃÊÊÃÊVÊVÕ`iÊ>ÊVÕÌÀiÃÊÌ iÀÊÌ >ÊÌ iÊ1°-°]Ê7iÃÌiÀÊÕÀ«i]Ê >>`>]Ê>«>]ÊÕÃÌÀ>>]Ê>`Ê iÜÊ<i>>`° Î°Ê Ài>ÃÊÜÌ Ê } ÊÀ>ÌiÃÊvÊ i«>ÌÌÃÊÊVÕ`iÊvÀV>]Ê >]ÊÀi>]Ê-ÕÌ i>ÃÌÊÃ>ÊVÕ`}Ê`iÃ>Ê>`ÊÌ iÊ* ««iÃ]Ê-ÕÌ Ê>`Ê7iÃÌiÀÊ*>VwVÊÃ>`Ã]ÊÌiÀÀÊ>âÊ >Ã]ÊViÀÌ>Ê«>ÀÌÃÊvÊÌ iÊ >ÀLLi>ʰi°]Ê>ÌÊ>`ÊÌ iÊV>Ê,i«ÕLV®]Ê>`ÊÌ iÊ``iÊ>ÃÌÊiÝVi«ÌÊÃÀ>i°ÊÀi>ÃÊÜÌ Ê`iÀ>ÌiÊÀ>ÌiÃÊVÕ`iÊ-ÕÌ Ê iÌÀ>Ê>`Ê -ÕÌ ÜiÃÌÊÃ>]ÊÃÀ>i]Ê>«>]Ê>ÃÌiÀÊ>`Ê-ÕÌ iÀÊÕÀ«i]Ê,ÕÃÃ>]Ê>`ÊÃÌÊvÊ iÌÀ>Ê>`Ê-ÕÌ ÊiÀV>° {°Ê ÃÌÊ>`ÕÌÃÊvÀÊ`iÀ>ÌiÊÀÊ } ÀÃÊ>Ài>ÃÊvÊÌ iÊÜÀ`Ê`ÊÌÊÜÊÌ iÀÊ i«>ÌÌÃÊÊÃÌ>ÌÕðÊÊ«>ÌiÌÃÊvÀÊÌ iÃiÊ>Ài>ÃÊii`Ê i«>ÌÌÃÊÊL`ÊÌiÃÌÃÊto determine if Ì iÞÊ >ÛiÊLiiÊ«ÀiÛÕÃÞÊviVÌi`°Ê/ iÊwÀÃÌÊ i«>ÌÌÃÊÊà ÌÊV>ÊLiÊ}ÛiÊ`ÕÀ}ÊÌ iÊÃ>iÊÛÃÌÊ>ÃÊÌ iÊL`ÊÌiÃÌÃÊLÕÌÊÞÊ>vÌiÀÊÌ iÊL`ÊÃÊ`À>ܰ Õâ>ÌÊVÌÊ >ÌÊÊUÊÊÜÜܰÕâi°À}ÉV>Ì}°`É«{äÎȰ«`vÊÊUÊÊÌiÊ*{äÎÈÊnÉ£Ó® 72 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Recommended Immunization Schedule, Minnesota 2011 Ages 0–6 Years Chart must be used with guidelines below. Age Vaccine Hepatitis B1 Rotavirus Birth HepB 2 1 month 2 4 6 12 15 18 19-23 months months months months months months months see footnote 1 HepB 4-6 years HepB RV RV RV Diphtheria, Tetanus, Pertussis3 DTaP DTaP DTaP Haemophilus influenzae type b4 Hib Hib Hib4 Hib Pneumococcal5 PCV PCV PCV PCV Inactivated Poliovirus6 IPV IPV Range of recommended ages 2 see footnote 3 DTaP DTaP Supplemental PCV13 PPSV IPV Influenza7 Measles, Mumps, Rubella 9 Hepatitis A10 Catch-up vaccination Certain high-risk groups IPV TIV (annually) 8 Varicella 2-3 years TIV or LAIV MMR MMR VAR VAR HepA series Meningococcal11 HepA series MCV • Additional vaccines may be licensed and recommended during the year. For updated information see www.cdc.gov/vaccines/pubs/ACIP-list.htm. • Licensed combination vaccines may be used whenever any components of the combination are indicated and other components of the vaccine are not contraindicated and if approved by the Food and Drug Administration for that dose of the series. Also consider provider assessment, patient preference, and potential for adverse events. • Consult the respective ACIP statement for detailed recommendations. • Report clinically significant adverse events that follow immunization to the Vaccine Adverse Event Reporting System (VAERS). For guidance on how to obtain and complete a VAERS form see http://vaers.hhs.gov/index or call 800-822-7967. 1. Hepatitis B (HepB). Minimum age: birth. At birth: • Give monovalent HepB to all newborns within 12 hours of birth. • If mother is HBsAg positive, give newborn HepB and 0.5 mL of hepatitis B immune globulin (HBIG) within 12 hours of birth. • If mother’s HBsAg status is unknown, give newborn HepB within 12 hours of birth. Determine mother’s HBsAg status as soon as possible and if HBsAg positive, give newborn HBIG as soon as possible and within 1 week. Following the birth dose: • Complete HepB series with either monovalent HepB or a combination vaccine containing HepB. Give second dose at age 1 or 2 months and final dose no sooner than age 24 weeks. Note: Combination vaccines are not indicated before age 6 weeks. It is permissible to give 4 doses of HepB when combination vaccines are given after the birth dose. • Infants that didn’t receive a birth dose should receive HepB on a schedule of 0,1, and 6 months. • Test infants born to HBsAg positive mothers for HBsAg and antibody to HBsAg after completion of 3 or more doses in HepB series, at age 9 through 18 months (generally at the next well-child visit). 4-month dose: • If monovalent HepB is used for doses after the birth dose, a dose at age 4 months is not needed. 2. Rotavirus (RV). Minimum age: 6 weeks. • Give first dose at age 6 through 14 weeks. Do not start the series at age 15 weeks and older. • Give final dose by age 8 months. Do not give a dose at age 8 months and older. • If Rotateq was used for either of the first 2 doses, give a total of 3 doses. • Rotarix only requires 2 doses at 2 months and 4 months. 3. Diphtheria, tetanus, and acellular pertussis (DTaP). Minimum age: 6 weeks. • Fourth dose may be given as early as age 12 months, provided at least 6 months have elapsed since third dose. • Give final dose at age 4 through 6 years. 4. Haemophilus influenzae type b (Hib). Minimum age: 6 weeks. • If PRP-OMP (PedvaxHIB or ComVax) is given at age 2 and 4 months, a dose at age 6 months is not necessary. • Hiberix should not be used for doses at age 2, 4, or 6 months but can be used as a booster following any Hib vaccine in children age 12 months and older. • Not routinely recommended for persons age 5 years and older; however, consider 1 dose for unvaccinated children with sickle cell disease, leukemia, or HIV infection, or who have had a splenectomy. 5. Pneumococcal (PCV, PPSV). Minimum ages: 6 weeks for pneumococcal conjugate vaccine (PCV); 2 years for pneumococcal polysaccharide vaccine (PPSV). Pneumococcal conjugate vaccine (PCV) • Give 1 dose of PCV to any unvaccinated child age 2 through 4 years. If they are at risk for invasive disease give a second dose 2 months after first dose. • Give PCV13 to complete any series started with PCV7. Minnesota Department of Health, IC#141-0188 (03/11) www.health.state.mn.us/immunize 6. 7. 8. 9. 10. 11. • Provide a single supplemental dose of PCV13 following a completed PCV7 series for: ○ Healthy children through age 4 years, ○ Children with certain medical conditions through age 5 years. • Allow 8 weeks between pneumococcal vaccine doses. • Consider a single supplemental dose of PCV13 for children age 6 through 18 years with anatomic or functional asplenia including sickle cell disease, immunocompromising conditions including HIV infection, cochlear implant, or CSF leaks. Pneumococcal polysaccharide vaccine (PPSV) • Give PPSV to certain high-risk groups age 2 years and older. See MMWR 2000; 49(RR-9):1-35. • A single revaccination is recommended 5 years after initial dose for children age 2 years and older with anatomic or functional asplenia or immunocompromising conditions. Inactivated poliovirus (IPV). Minimum age: 6 weeks. • Always give final dose between age 4 through 6 years, regardless of the number of doses previously given. • Give final dose at least 6 months after previous dose. Influenza, seasonal (TIV, LAIV). Minimum ages: 6 months for trivalent inactivated influenza vaccine (TIV); 2 years for live, attenuated influenza vaccine (LAIV). • Give annually to all children: TIV for age 6 months through 2 years and TIV or LAIV for healthy children age 2 through 18 years. • Give 2 doses separated by at least 4 weeks to children younger than age 9 years who are receiving influenza vaccine for the first time or who were vaccinated for the first time last season and only received 1 dose. Measles, mumps, and rubella (MMR). Minimum age: 12 months. • Give first dose on or after first birthday. • Give second dose at age 4 through 6 years. It may be given earlier provided at least 4 weeks have elapsed since first dose. Varicella (VAR). Minimum age: 12 months. • Give first dose on or after first birthday. • Give second dose at age 4 through 6 years. It may be given earlier provided that at least 3 months have elapsed since first dose. If second dose was given at least 28 days after the first dose, it does not need to be repeated. Hepatitis A (HepA). Minimum age: 12 months. • Give 2 doses at least 6 months apart to all children at age 1 year. If not fully vaccinated by age 2 years child can be vaccinated at a subsequent visit. • Consider catch-up vaccination for children through age 18 years. Meningococcal conjugate vaccine (MCV). Minimum age: 2 years. • Give 2 doses 2 months apart to children age 2 years and older with persistent complement component deficiency, anatomic or functional asplenia, or HIV infection and 1 dose every 5 years thereafter. • Give 1 dose of MCV to children through age 6 years who received meningococcal polysaccahride vaccine (MPSV) or MCV three or more years previously and who remain at risk (i.e., travel to endemic areas). Page 2 of 4 CDC’s National Immunization Hotline (in English and Spanish): 800-CDC-INFO (1-800-232-4636), TTY 888-232-6348 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 73 Recommended Immunization Schedule, Minnesota 2011 Ages 7–18 Years Chart must be used with guidelines below. Age Vaccine Tetanus, Diphtheria, Pertussis1 2 Human Papillomavirus Meningococcal3 7–10 years 11–12 years 13–18 years see footnote 1 Tdap Tdap see footnote 2 HPV (3 doses) HPV series MCV MCV MCV Influenza4 PPSV / PCV Hepatitis A6 HepA series Hepatitis B7 HepB series Inactivated Poliovirus8 Catch-up vaccination Certain high-risk groups TIV or LAIV (annually) Pneumococcal5 Range of recommended ages IPV series Measles, Mumps, Rubella9 MMR Varicella10 VAR • Additional vaccines may be licensed and recommended during the year. For updated information see www.cdc.gov/vaccines/pubs/ACIP-list.htm. • Licensed combination vaccines may be used whenever any components of the combination are indicated and other components of the vaccine are not contraindicated and if approved by the Food and Drug Administration for that dose of the series. Also consider provider assessment, patient preference, and potential for adverse events. • Consult the respective ACIP statement for detailed recommendations. • Report clinically significant adverse events that follow immunization to the Vaccine Adverse Event Reporting System (VAERS). For guidance on how to obtain and complete a VAERS form see http://vaers.hhs.gov/index or call 800-822-7967. 1. Tetanus, diphtheria, and acellular pertussis (Tdap). Minimum ages: 10 years for Boostrix and 11 years for Adacel. • Give Tdap at age 11 or 12 years for those who have completed the recommended childhood DTP/DTaP series but have not received a Td booster dose. • Give Tdap to adolescents age 13 through 18 years who have not already received a Tdap. • Tdap can be administered regardless of the interval since the last tetanus and diphtheria toxoid–containing vaccine. • Persons age 7 through 10 years who are not fully immunized against pertussis (including those never vaccinated or with unknown pertussis vaccination status) should receive a single dose of Tdap. Refer to the catch-up schedule if additional doses of tetanus and diphtheria toxoid–containing vaccine are needed. 2. Human papillomavirus (HPV). Minimum age: 9 years. • Give 3-dose HPV series to all females at age 11 or 12 years and to all unvaccinated females at age 13 through 18 years at intervals of 0, 2, and 6 months. • Give HPV2 to prevent cervical cancer. • Give HPV4 to prevent cervical, vaginal, and vulvar cancers and genital warts. • Ideally, vaccine should be given prior to potential exposure through sexual activity; however, sexually active females should still be vaccinated. Inform sexually active females that they may not receive protection against all HPV types in the vaccine if previously exposed to any of them. • As appropriate also instruct females to receive annual Pap smears. • HPV4 may be given to males age 9 through 18 years to reduce the likelihood of acquiring genital warts. 3. Meningococcal conjugate vaccine (MCV). Minimum age: 2 years. • Give 1 dose of MCV at age 11 or 12 years and a booster dose at age 16 years. • Give 1 dose of MCV to unvaccinated adolescents age 13 through 18 years including unvaccinated college freshmen living in dormitories. If vaccinated at age 13 through 15 years, give a booster dose at age 16 though 18 years (i.e., 3 years later). • Give 2 doses 2 months apart to children age 2 years and older with persistent complement component deficiency or anatomic or functional asplenia and 1 dose every 5 years thereafter. • Give 2 doses 2 months apart to adolescents age 11 through 18 years who are HIV positive. • Give 1 dose of MCV to children age 7 years and older who received meningococcal polysaccahride vaccine (MPSV) or MCV five or more years previously and who remain at risk. Minnesota Department of Health, IC#141-0188 (03/11) www.health.state.mn.us/immunize 4. Influenza, seasonal (TIV, LAIV). Minimum ages: 6 months for TIV; 2 years for LAIV. • Give annually to all children age 6 months through 18 years. • For healthy nonpregnant persons age 2 through 49 years, use either LAIV or TIV. • Give 2 doses separated by at least 4 weeks to children younger than age 9 years who are receiving influenza vaccine for the first time or who were vaccinated for the first time last season and only received 1 dose. 5. Pneumococcal polysaccharide vaccine and pneumococcal conjugate vaccine (PPSV and PCV). Minimum ages: 2 years for PPSV; 6 weeks for PCV. • Give PPSV to certain high-risk groups. See MMWR 2010; 59(RR-11);1–24. • A single revaccination is recommended 5 years after initial dose for children age 2 years and older with anatomic or functional asplenia or immunocompromising conditions. • Consider a single supplemental dose of PCV13 for children age 6 through 18 years with anatomic or functional asplenia including sickle cell disease or immunocompromising conditions including HIV infection, cochlear implant, or CSF leaks. 6. Hepatitis A (HepA). Minimum age: 12 months. • Give 2 doses at least 6 months apart. • Consider catch-up vaccination for children through age 18 years. 7. Hepatitis B (HepB). Minimum age: birth. • Give a 3-dose series to unvaccinated children (see catch-up schedule). • A 2-dose series 4 to 6 months apart of adolescent formulation Recombivax HB is licensed for children ages 11 through 15 years. 8. Inactivated poliovirus (IPV). Minimum age: 6 weeks. • Give 3 doses of IPV to unvaccinated children age 7 through 17 years (see catch-up schedule). • IPV is not routinely recommended for persons age 18 years and older. • If both OPV and IPV were given as part of a series, a total of 4 doses should be given, regardless of child’s current age. 9. Measles, mumps, and rubella (MMR). Minimum age: 12 months. • Give 2 doses of MMR at least 4 weeks apart to all unvaccinated children. 10. Varicella (VAR). Minimum age: 12 months. • Give 2 doses to persons without evidence of immunity (i.e., who have not received 2 doses of varicella or have no physician diagnosis of varicella or shingles disease). ੦ For persons younger than age 13 years give 2 doses at least 3 months apart. Do not repeat second dose if given 28 days or more after first dose. ੦ For persons age 13 years and older give 2 doses at least 4 weeks apart. Page 3 of 4 CDC’s National Immunization Hotline (in English and Spanish): 800-CDC-INFO (1-800-232-4636), TTY 888-232-6348 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html 74 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Catch-Up Schedule and Minimum Intervals for Children and Adolescents There is no need to restart a vaccine series no matter how much time has elapsed between doses. Catch-Up Schedule for Ages 4 Months Through 6 Years Minimum Interval Between Doses Dose 2 to Dose 3 Dose 3 to Dose 4 Minimum Age for Dose 1 Dose 1 to Dose 2 Birth 4 weeks 8 weeks1 (and 16 weeks after first Rotavirus2 6 weeks 4 weeks 4 weeks if Rotateq was used for any Diphtheria, Tetanus, Pertussis3 6 weeks 4 weeks Vaccine Hepatitis B1 dose). previous dose(s). 4 weeks 4 weeks if first dose given before age 12 months. Haemophilus influenzae type b4 8 weeks (as final dose) if first dose 6 weeks Pneumococcal5 Inactivated Poliovirus6 Measles, Mumps, Rubella7 Varicella8 Hepatitis A9 6 weeks 12 months 12 months 12 months Tetanus, Diphtheria; Tetanus, Diphtheria, Pertussis10 12 months Birth 6 months 4 weeks 6 weeks 4 weeks Measles, Mumps, Rubella7 12 months 4 weeks 3 months if person is younger than Varicella8 12 months Inactivated Poliovirus Meningococcal12 No further doses needed for healthy children if previous dose given at age 24 months and older. 8 weeks (as final dose) The fourth dose is only necessary for children age 12 months to 5 years who received 3 doses before age 12 months. For at-risk children age 24 through 59 months give PCV if 3 doses received previously. 4 weeks 6 months6 age 12 months. 6 months if first dose given at age 12 months and older. 4 weeks 6 children) if current age is 12 months and older. 8 weeks if first dose given before 9 years Hepatitis A Hepatitis B1 8 weeks (as final dose for healthy The fourth dose is only necessary for children age 12 months to 5 years who received 3 doses before age 12 months. Minimum Interval Between Doses Dose 2 to Dose 3 Dose 3 to Dose 4 Dose 1 to Dose 2 4 weeks 9 4 weeks if current age is less than 12 months. 4 weeks 4 weeks 3 months 6 months 7 years10 Human Papillomavirus11 12 months. Catch-Up Schedule for Ages 7 Through 18 Years Minimum Age for Dose 1 Vaccine 6 months3 8 weeks (as final dose)4 if current age 8 weeks (as final dose) given at age 12 through 14 months. 4 weeks if first dose given before age 12 months and current age is less than 24 months. 8 weeks (as final dose for healthy children) if first dose given at age 12 months and older or current age is 24 through 59 months. No further doses needed for healthy children if first dose given at age 24 through 59 months. 6 months 4 weeks4 if current age is less than is 12 months or older and second dose given before age 15 months. No further doses needed if No further doses needed if first previous dose given at age 15 months dose given at age 15 months and older. and older. 6 weeks Dose 4 to Dose 5 2 years Dose 4 to Dose 5 6 months if first dose given before age 12 months. 12 weeks (and at least 6 months after first dose). 8 weeks (and 16 weeks after first dose). 6 months as final dose. 4 weeks if person has received both IPV and OPV and requires 4 doses. 6 months6 age 13 years. 4 weeks if person is age 13 years and older. 2 months 1. Hepatitis B (HepB). • Final dose should not be given before age 24 weeks. • A 2-dose series 4 to 6 months apart of adolescent formulation Recombivax HB is licensed for ages 11 through 15 years. 2. Rotavirus (RV). • Do not start the series at age 15 weeks and older. • Do not give a dose on or after age 8 months. • If Rotateq was used for either of the first 2 doses, give a total of 3 doses. 3. Diphtheria, tetanus, and acellular pertussis (DTaP). • Fifth dose is not necessary if fourth dose was given at age 4 years or older. • Not indicated for persons age 7 years and older. 4. Haemophilus influenzae type b (Hib). • Consider 1 dose for unvaccinated high-risk persons age 5 years and older with sickle cell disease, leukemia, or HIV infection, or who have had a splenectomy. • If current age is under 12 months and first 2 doses were PRP-OMP (PedvaxHIB or ComVax), give third (and final) dose at age 12 through 15 months and at least 8 weeks after second dose. • If first dose was given at age 7 through 11 months, give 2 doses separated by 4 weeks plus a booster at age 12 through 15 months. 5. Pneumococcal conjugate vaccine (PCV). • Generally not recommended for children age 5 years and older. • Give 1 dose to healthy children age 2 through 4 years who have not received at least 1 dose of PCV on or after 12 months of age. • Give at-risk children age 2 through 5 years 1 dose if 3 doses received previously or give 2 doses 8 weeks apart if child has received fewer than 3 doses. • Consider a single supplemental dose of PCV13 for children age 6 through 18 years with anatomic or functional asplenia including sickle cell disease, immunocompromising conditions including HIV infection, cochlear implant, or CSF leaks. 6. Inactivated poliovirus (IPV). • For children who received an all-IPV or all-oral poliovirus (OPV) series, a fourth dose is not necessary if third dose was given at age 4 years or older and at least 6 months has elapsed from previous dose. CDC’s National Immunization Hotline: 800-CDC-INFO (1-800-232-4636), TTY 888-232-6348 • If both OPV and IPV were given as part of a series, give a total of 4 doses, regardless of child’s current age. • IPV is not routinely recommended for persons age 18 years and older. • Always give final dose on or after age 4 years, regardless of the number of doses previously given. • Give final dose at least 6 months from previous dose. • In children age 6 months and younger; apply minimum age and intervals only if there is an imminent risk of exposure, i.e., community outbreak or travel to endemic areas. 7. Measles, mumps, and rubella (MMR). • Second dose is recommended routinely at age 4 through 6 years but may be given earlier. • Give 2 doses of MMR at least 4 weeks apart to all previously unvaccinated children. • MMR and varicella may be given simultaneously; otherwise separate them by at least 4 weeks. 8. Varicella (VAR). . • Second dose is recommended routinely at age 4 through 6 years but may be given earlier. • If the second dose is given at least 28 days following the first dose it can be considered valid. 9. Hepatitis A (HepA). • Consider catch-up vaccination for children through age 18 years. 10. Tetanus and diphtheria (Td) and tetanus, diphtheria, and acellular pertussis (Tdap). • Substitute Tdap for one dose of Td in the primary catch-up series and use Td for other doses. • Give Tdap in place of Td booster dose for children age 11 through 18 years. 11. Human papillomavirus (HPV). • Give HPV2 or HPV4 series to all unvaccinated females at age 13 through 18 years. May give HPV4 to males age 9 through 18 years. • Follow the dose intervals of 0, 2, and 6 months as closely as possible. 12. Meningococcal conjugate vaccine (MCV). • Give 1 dose of MCV to unvaccinated adolescents age 13 through 18 years. If vaccinated at age 13 through 15 years, give a booster dose at age 16 though 18 years (i.e., 3 years later). • Give 2 doses 2 months apart to adolescents age 11 through 18 years who are HIV positive. • Give 2 doses 2 months apart to children age 2 years and older with persistent complement component deficiency or anatomic or functional asplenia and 1 dose every 5 years thereafter. Page 4 of 4 (03/11) Minnesota Department of Health: www.health.state.mn.us/immunize Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 75 76 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Charts must be used with footnotes on next page. Recommended Adult Immunization Schedule Assess the vaccination status of adult patients at every visit. Vaccine Age 19 through 26 years 27 through 49 years 50 through 59 years 60 through 64 years 65 years and older 1 dose annually Influenza1* Substitute 1-time dose of Tdap for next Td Tetanus, Diphtheria, Pertussis2* Human Papillomavirus3* Td booster every 10 years 3 doses (0, 1-2, 6 months) 2 doses (0, 4−8 weeks) Varicella4* 1 dose (60 years and older) Zoster5 1 - 2 doses Measles, Mumps, Rubella6* 1 - 2 doses 1 - 2 doses Pneumococcal7 1 dose Hepatitis A8* 2 doses (0, 6 months) Hepatitis B9* 3 doses (0, 1, 6 months) Meningococcal10* 1 or more doses Vaccines Indicated for Adults Based on Medical and Other Indications Indication Vaccine HIV infection11,12 ImmunoAsplenia12 (including CD4+ T Men who Heart disease, elective splenectomy compromising Chronic conditions (excluding lymphocyte count have sex chronic lung and persistent liver Pregnancy human immunodewith men disease, chronic complement <200 ≥200 disease ficiency virus [HIV] alcoholism component (MSM) cells/μL cells/μL infection)11,12 deficiencies) Influenza 1* 1 dose TIV or LAIV annually 1 dose TIV annually Tetanus, Diphtheria, Pertussis 2* Human Papillomavirus 3* Diabetes, Health Kidney failure, care end-stage renal personnel disease, on (HCP) hemodialysis 1 dose TIV annually 1 dose TIV or LAIV annually Substitute 1-time dose of Tdap for next Td; then boost with Td every 10 years 3 doses for males and females through age 26 years Varicella 4* Contraindicated Zoster 5 Contraindicated Measles, Mumps, Rubella 6* Contraindicated 2 doses 1 dose 1 or 2 doses 1 or 2 doses Pneumococcal 7 Hepatitis A 8* 3 doses females through age 26 years; males through age 21 years 2 doses Hepatitis B 9* Meningococcal 10* 3 doses 1 or more doses *Covered by the National Vaccine Injury Compensation Program (see back for more information) Recommended for all persons who meet the age requirements and who lack evidence of immunity (i.e., no documented vaccination, no evidence of prior infection, or no laboratory evidence of immunity) Recommended if some other risk factor is present (e.g., based on medical, occupational, lifestyle, or other indications) Contraindicated No recommendation Minnesota Department of Health, IC#141-0316 (01/12) www.health.state.mn.us/immunize Page 2 of 4 CDC’s National Immunization Hotline (in English and Spanish): 800-CDC-INFO (1-800-232-4636), TTY 888-232-6348 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 77 1. Influenza, seasonal (TIV, LAIV) trivalent inactivated influenza vaccine (TIV); live attenuated influenza vaccine (LAIV). • Give LAIV or TIV to healthy (i.e., without high-risk medical conditions) nonpregnant adults under age 50 years. • Give TIV to: ○ Persons with high-risk medical conditions. ○ Persons age 50 years and older. ○ Health care personnel (HCP) who care for severely immunocompromised patients in protective isolation. 2. Tetanus and diphtheria (Td) and tetanus, diphtheria, and pertussis (Tdap) • Give 1 dose of Tdap to adults age 64 years and younger in place of their next 10-year booster dose of Td. Td is recommended every 10 years as a booster for all adults. • Tdap is recommended for adults having close contact with infants under age 1 year including (parents, grandparents, child care staff, pregnant women after 20 weeks gestation, and HCP). • Tdap can be given regardless of when the last Td was given. • Adults with unknown or incomplete history of completing primary vaccination should complete a 3-dose primary series of Td (see page 4 for catch-up schedule). Give Tdap for 1 of the 3 doses. • Pregnant women not vaccinated during pregnancy should receive Tdap in the immediate postpartum period. • Adults age 65 years and older may also receive Tdap. 3. Human papillomavirus (HPV2, HPV4) • Give HPV2 or HPV4 to all females through age 26 years and HPV4 to males through age 21 years. • HPV4 is recommended for males through age 26 years who are immunocompromised or men who have sex with men. • HPV is given as a 3 dose series at intervals of 0, 1-2, and 6 months. • Ideally, vaccine should be given prior to potential exposure through sexual activity; however, sexually active persons should still be vaccinated. Inform them that they may not receive protection against all HPV types in the vaccine if previously exposed to any of them. • Instruct all females to continue to receive annual Pap smears. • HPV4 may be given to males age 22 through 26 years. 4. Varicella (VAR) • Give varicella vaccine as 2 doses separated by 4 to 8 weeks to all adults without evidence of immunity, particularly those who will have close contact with persons at high risk for serious complications (e.g., HCP and family contacts of immunocompromised persons), or at high-risk of exposure (e.g., child care personnel, teachers). • Evidence of immunity to varicella includes any of the following: ○ Documentation of 2 doses of varicella vaccine at least 4 weeks apart, or ○ U.S.-born before 1980, or ○ History of varicella disease verified by a health care provider, or ○ History of herpes zoster disease verified by a health care provider, or ○ Laboratory evidence of immunity. • When assessing immunity of HCP or pregnant women the “U.S.–born before 1980” evidence of immunity should not be considered. ○ HCP with no other evidence of immunity should be given 2 doses of varicella at least 4 to 8 weeks apart. ○ Pregnant women with no other evidence of immunity should be vaccinated upon completion of pregnancy. 5. Zoster (ZOS) • Give 1 dose of zoster vaccine to persons age 60 years and older, regardless of a previous herpes zoster infection. • Persons with chronic medical conditions may be vaccinated unless it is specifically contraindicated, see Vaccines Indicated for Adults Based on Medical and Other Indications chart on page 2. 6. Measles, mumps, rubella (MMR) • Adults born before 1957 are generally considered immune to measles and mumps. • Post-secondary students, persons working in health care facilities, and international travelers need a second dose at least 4 weeks after their first dose. • HCP born before 1957: If they lack evidence of immunity, i.e., documentation of immunization or laboratory confirmation, give 2 doses of MMR at least 4 weeks apart. • Issues specific to measles and mumps: Adults born in 1957 or later should receive 1-2 doses of MMR vaccine unless they have evidence of immunity, which includes: ○ Documentation of 1 or more doses of MMR (or measles vaccine), or ○ History of disease based on health care provider diagnosis, or ○ Laboratory evidence of immunity. ○ Revaccination is recommended for persons that received inactivated (killed) measles vaccine or measles vaccine of unknown type received from 1963 to 1967. • Rubella-specific issues: Women of childbearing age should have rubella immunity assessed and be given MMR if susceptible. If assessment is performed during pregnancy and if susceptible, give MMR upon completion of pregnancy. Minnesota Department of Health, IC#141-0316 (01/12) www.health.state.mn.us/immunize 7. Pneumococcal (PPSV)− Give pneumococcal polysaccharide vaccine (PPSV) to: • All adults age 65 years and older. • Adults younger than age 65 years with chronic cardiovascular disease, chronic pulmonary disease including asthma, diabetes mellitus, alcoholism, chronic liver disease including cirrhosis, CSF leaks, cochlear implants, anatomic or functional asplenia, HIV infection, malignancy, chronic renal failure, nephrotic syndrome, receiving immunosuppressive chemotherapy, who smoke cigarettes, or live in a nursing home or long-term care facility. • Timing: Give PPSV at least 2 weeks prior to an elective splenectomy or when chemotherapy or other immunosuppressive treatment is anticipated. Give PPSV to HIV positive persons as soon as possible after diagnosis. Revaccination • Once-in-a-lifetime revaccination recommended if a person was vaccinated 5 or more years ago and either: ○ Was under age 65 years when first vaccinated and is now age 65 years and older, or ○ Is under age 65 years and at highest risk for invasive pneumococcal infection: chronic renal failure or nephrotic syndrome, anatomic or functional asplenia, or immunocompromising conditions. 8. Hepatitis A (HepA) • Give 2 doses of hepatitis A vaccine 6 months apart to: ○ Persons traveling to or working in countries with intermediate to high rates of HAV. ○ Men who have sex with men. ○ Persons who use street drugs. ○ Persons with chronic liver disease. ○ Persons who receive clotting factor concentrates. ○ Persons working with HAV in research settings or with HAV-infected primates. ○ Persons in close contact (e.g., household or regular child care contact) with an international adoptee during the first 60 days after arrival of the adoptee from an intermediate or high HAV endemic area. Vaccinate at least 2 weeks prior to adoptee’s arrival. ○ Other adults wishing to obtain immunity. 9. Hepatitis B (HepB)− Give 3 doses of hepatitis B vaccine at intervals of 0, 1, and 6 months to all high-risk adults. Indications grouped by risk are as follows: • Occupational: health care and public safety personnel who are exposed to blood or other potentially infectious bodily fluids. • Behavioral: sexually active persons who are not in a long-term mutually monogamous relationship, injection-drug users, persons with a recently acquired STD, clients of STD clinics, and men who have sex with men. • Medical: those with HIV infection, chronic liver disease, persons younger than age 60 years with diabetes, end-stage renal disease, or on dialysis. • Other: household contacts and sex partners of persons with chronic hepatitis B virus (HBV) infection, clients and staff of institutions for the developmentally disabled, jail and prison inmates, persons in drug treatment, and international travelers to countries with intermediate or high rates of HBV. • Higher dosing of HepB is recommended for persons undergoing hemodialysis or who are immunocompromised. Give Recombivax HB 40 mcg at intervals of 0, 1, and 6 months or Engerix-B 20 mcg at intervals of 0, 1, 2, and 6 months. 10. Meningococcal (MCV, MPSV) Meningococcal conjugate vaccine (MCV) • Give a 2-dose series at intervals of 0, 2 months to: ○ Persons with persistent complement component deficiency, anatomic or functional asplenia. ○ Persons with HIV infection who are at risk due to other indicators (e.g., travel to endemic areas, lab personnel working with N. meningitidis). • Give 1 dose to: ○ Persons traveling to countries with endemic meningococcal disease. It is required for travelers to Saudi Arabia during annual Hajj. ○ Military recruits. ○ Lab personnel working with N. meningitidis. ○ College students through age 21 years and living in freshmen dormitories if they have not received MCV on or after their 16th birthday. • Give MCV every 5 years following initial vaccination for adults who remain at risk and are age 54 years and younger. Meningococcal polysaccharide vaccine (MPSV) • Give one dose of MPSV to adults age 56 years and older who have any of the above risk factors. • Give MPSV every 5 years to persons age 56 years or older who remain at risk for meningococcal disease. 11. Immunocompromising conditions • Inactivated vaccines generally are acceptable, e.g., pneumococcal, meningococcal, and inactivated influenza vaccine. However, the immune response and efficacy may be reduced. • Generally avoid live vaccines for persons with immune deficiencies or immunocompromising conditions. • Information on specific conditions is available at www.cdc.gov/vaccines/pubs/acip-list.htm. 12. Selected conditions for which Haemophilus influenzae type b (Hib) vaccine may be used • Consider 1 dose for any unvaccinated persons who have sickle cell disease, leukemia, HIV infection, or who have had a splenectomy. Page 3 of 4 CDC’s National Immunization Hotline (in English and Spanish): 800-CDC-INFO (1-800-232-4636), TTY 888-232-6348 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html 78 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Catch-Up Schedule and Minimum Intervals for Adults This catch-up schedule must be used together with the guidelines printed on the previous page(s). Doses to be given and minimum intervals from previous dose for adults age 19 years and older Vaccine Minimum Interval Between Doses Schedule Tetanus, Diphtheria (Td) Tetanus, Diphtheria, Pertussis (Tdap) Human Papillomavirus (HPV) 0, 1, 7 months Dose 1 to 2 Dose 2 to 3 Booster Dose 4 weeks 6 months Td: 10 years after completing the primary series or since last booster dose Give Tdap for one of the doses in the series 0, 1-2, 6 months 4 weeks Varicella (VAR) 0, 4 weeks 4 weeks Measles, Mumps, Rubella (MMR)1 0, 4 weeks 4 weeks Hepatitis A (HepA) 0, 6 months 6 months Hepatitis B (HepB) 0, 1, 6 months 4 weeks 12 weeks and at least 6 months after first dose 8 weeks and at least 16 weeks after first dose 1. Measles, mumps, and rubella vaccines • May be given simultaneously, otherwise they must be separated by at least 4 weeks. • A Mantoux test can be given simultaneously with any live or inactivated vaccine. If the patient already received MMR vaccine, the Mantoux test must be delayed for at least 4 weeks after MMR vaccination. If the Mantoux was applied first, any vaccine, including MMR can be given at any time. Guidelines for Patients with an Incomplete or Nonexistent Vaccine History • There is no need to restart a vaccine series no matter how much time has elapsed between doses. • For refugees and immigrants, provide vaccinations as you would for any other adult patient. For translations of foreign vaccine terms and vaccine products visit the Immunization Action Coalition website at www.immunize.org/izpractices/p5122.pdf. • Patients age 18 years and older, including foreign-born adults, do not need polio vaccination unless they are traveling to a country where wild poliovirus still exists. • Count only documented vaccinations (i.e., including month, year, and preferably, day of vaccination). If no documentation exists, assume the patient is unvaccinated. It is always better to vaccinate when in doubt, rather than miss an opportunity to provide protection. National Vaccine Injury Compensation Program When vaccinating adults with vaccines covered by the Vaccine Injury Compensation Program, a Vaccine Information Statement (VIS) must be given each time the patient receives vaccine. The date of the edition of VIS given and the date the VIS was provided to the patient must be documented in the clinic/patient record. Other required documentation includes date of vaccination, name of the vaccine, manufacturer, and lot number; and name, address, and title of the individual who gave the vaccine. Download the most current VISs from the Immunization Action Coalition website at www.immunize.org/vis. Reporting Adverse Reactions Report adverse reactions to vaccines through the federal Vaccine Adverse Event Reporting System (VAERS). For information on reporting reactions following vaccines given by private clinics, call the 24-hour national toll-free information line, 800-822-7967. You may also visit http://vaers.hhs.gov/index. Report reactions to vaccines given in public clinics to the Minnesota Department of Health, 651-201-5414 or toll-free 877-676-5414. Minnesota Department of Health, IC#141-0316 (03/11) Disease Reporting Report suspected cases of vaccine-preventable diseases to the local health department or to the Minnesota Department of Health, P.O. Box 64975, St. Paul, MN 55164-0975, 651-201-5414 or toll-free 877-6765414. Page 4 of 4 www.health.state.mn.us/immunize Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/schedules.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 79 80 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 July 2011, Minnesota Department of Health Got Your Shots? 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Immunization (Ages birth through 18 years) 82 www.health.state.mn.us/immunize Got Your Shots? 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Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 83 1147 Give IM or SC Pneumococcal polysaccharide Give IM Pneumococcal conjugate 1$7 Give IM Hib Haemophilus influenzae UZQFC Vaccine name and route t(JWFEPTFBUMFBTUXLTBGUFSGJOBMEPTFPG1$7UPIJHISJTL DIJMESFOBHFZSTBOEPMEFS t'PSDIJMESFOXIPIBWFBOJNNVOPDPNQSPNJTJOHDPOEJUJPOPSIBWF TJDLMFDFMMEJTFBTFPSGVODUJPOBMPSBOBUPNJDBTQMFOJBHJWFBOE EPTFPG1147ZSTBGUFSQSFWJPVT1147DPOTVMU"$*11147 SFDPNNFOEBUJPOTBUXXXDEDHPWWBDDJOFTQVCT"$*1MJTUIUN **High-risk: 5IPTFXJUITJDLMFDFMMEJTFBTFBOBUPNJDPS GVODUJPOBMBTQMFOJBDISPOJDDBSEJBDQVMNPOBSZPSSFOBM EJTFBTFEJBCFUFTDFSFCSPTQJOBMGMVJEMFBLT)*7JOGFDUJPO JNNVOPTVQQSFTTJPOEJTFBTFTBTTPDJBUFEXJUIJNNVOPTVQ QSFTTJWFBOEPSSBEJBUJPOUIFSBQZPSXIPIBWFPSXJMMIBWF BDPDIMFBSJNQMBOU t'PSNJOJNVNJOUFSWBMTTFFSECVMMFUBUMFGU t'PSBHFoN*GIJTUPSZPGEPTFTHJWFEPTFTPG1$7 XLTBQBSUXJUIBSEEPTFBUBHFoNJGIJTUPSZPGPS EPTFTHJWFEPTFPG1$7XJUIBOEEPTFBUBHFoNBU MFBTUXLTMBUFS t'PSBHFoN*GVOWBDDJOBUFEPSIJTUPSZPGEPTFCFGPSFBHF NHJWFEPTFTPG1$7XLTBQBSUJGIJTUPSZPGEPTFBU PSBGUFSBHFNPSPSEPTFTCFGPSFBHFNHJWFEPTFPG 1$7BUMFBTUXLTBGUFSNPTUSFDFOUEPTFJGIJTUPSZPGEPTFT PG1$7PSPUIFSBHFBQQSPQSJBUFDPNQMFUF1$7TDIFEVMFHJWF TVQQMFNFOUBMEPTFPG1$7BUMFBTUXLTBGUFSUIFNPTUSFDFOU EPTF t'PSBHFoNBOEIFBMUIZ*GVOWBDDJOBUFEPSBOZJODPNQMFUF TDIFEVMFPSJGEPTFTPG1$7PSBOZPUIFSBHFBQQSPQSJBUFDPN QMFUF1$7TDIFEVMFHJWFTVQQMFNFOUBMEPTFPG1$7BUMFBTU XLTBGUFSUIFNPTUSFDFOUEPTF t'PSBHFoNBOEBUIJHISJTL*GVOWBDDJOBUFEPSBOZJODPN QMFUFTDIFEVMFPGPSEPTFTHJWFEPTFTPG1$7BUMFBTU XLTBGUFSUIFNPTUSFDFOUEPTFBOEBOPUIFSEPTFBUMFBTUXLT MBUFSJGBOZJODPNQMFUFTFSJFTPGEPTFTPSJGEPTFTPG1$7PS BOZPUIFSBHFBQQSPQSJBUFDPNQMFUF1$7TDIFEVMFHJWFTVQQMF NFOUBMEPTFPG1$7BUMFBTUXLTBGUFSUIFNPTUSFDFOU1$7EPTF t'PSDIJMESFOBHFTUISPVHIZSTXJUIGVODUJPOBMPSBOBUPNJD BTQMFOJBJODMVEJOHTJDLMFDFMMEJTFBTF )*7JOGFDUJPOPSPUIFS JNNVOPDPNQSPNJTJOHDPOEJUJPODPDIMFBSJNQMBOUPS$4'MFBL DPOTJEFSHJWJOHEPTFPG1$7SFHBSEMFTTPGQSFWJPVTIJTUPSZPG 1$7PS1147 All Hib vaccines: t*GXBTHJWFOBUoNHJWFCPPTUFSJOXLT t(JWFPOMZEPTFUPVOWBDDJOBUFEDIJMESFOBHFTUISPVHIN ActHib: tBOENBZCFHJWFOXLTBGUFSQSFWJPVTEPTF t*GXBTHJWFOBUBHFoNPOMZEPTFTBSFOFFEFEJT HJWFOoXLTBGUFSUIFOCPPTUBUBHFoNXBJUBUMFBTU XLTBGUFSEPTF PedvaxHIB and Comvax: tNBZCFHJWFOXLTBGUFSEPTF t"DU)JC1315 HJWFBUBHFNNNoNCPPTUFSEPTF t1FEWBY)*#PS$PNWBYDPOUBJOJOH1310.1 HJWFBUBHFNN oNCPPTUFSEPTF t%PTFPG)JCWBDDJOFTIPVMEOPUCFHJWFOFBSMJFSUIBOBHFXLT t(JWFGJOBMEPTFCPPTUFSEPTF OPFBSMJFSUIBOBHFNBOEBNJOJ NVNPGXLTBGUFSUIFQSFWJPVTEPTF t)JCWBDDJOFTBSFJOUFSDIBOHFBCMFIPXFWFSJGEJGGFSFOUCSBOETPG )JCWBDDJOFTBSFBENJOJTUFSFEGPSEPTFBOEEPTFBUPUBMPG EPTFTJTOFDFTTBSZUPDPNQMFUFUIFQSJNBSZTFSJFTJOJOGBOUT t"OZ)JCWBDDJOFNBZCFVTFEGPSUIFCPPTUFSEPTF t)JCJTOPUSPVUJOFMZHJWFOUPDIJMESFOBHFZSTBOEPMEFS t)JCFSJYJTBQQSPWFE0/-:GPSUIFCPPTUFSEPTFBUBHFNUISPVHIZST t(JWFBUBHFTNNNoN t%PTFNBZCFHJWFOBTFBSMZBTBHFXLT t8IFODIJMESFOBSFCFIJOEPO1$7TDIFEVMFNJOJNVNJOUFSWBMGPS EPTFTHJWFOUPDIJMESFOZPVOHFSUIBOBHFNJTXLTGPSEPTFT HJWFOBUNBOEPMEFSJUJTXLT t(JWFEPTFUPVOWBDDJOBUFEIFBMUIZDIJMESFOBHFoN t'PSIJHISJTLDIJMESFOBHFToN(JWFEPTFTBUMFBTUXLT BQBSUJGUIFZQSFWJPVTMZSFDFJWFEGFXFSUIBOEPTFTHJWFEPTF BUMFBTUXLTBGUFSUIFNPTUSFDFOUEPTFJGUIFZQSFWJPVTMZSFDFJWFE EPTFT t1$7JTOPUSPVUJOFMZHJWFOUPIFBMUIZDIJMESFOBHFZSTBOEPMEFS Schedule for catch-up vaccination and related issues Schedule for routine vaccination and other guidelines BOZWBDDJOFDBOCFHJWFOXJUIBOPUIFS (Page 3 of 4) 1/12 Contraindication 1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPS UPBOZPGJUTDPNQPOFOUT Precaution .PEFSBUFPSTFWFSFBDVUFJMMOFTT Contraindication 1SFWJPVTBOBQIZMBYJTUPB1$7WBDDJOF UPBOZPGJUTDPNQPOFOUTPSUPBOZ EJQIUIFSJBUPYPJEDPOUBJOJOHWBDDJOF Precaution .PEFSBUFPSTFWFSFBDVUFJMMOFTT Contraindications t1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPS UPBOZPGJUTDPNQPOFOUT t"HFZPVOHFSUIBOXLT Precaution .PEFSBUFPSTFWFSFBDVUFJMMOFTT Contraindications and precautions NJMEJMMOFTTJTOPUBDPOUSBJOEJDBUJPO Summary of Recommendations for Child/Teen Immunization (Ages birth through 18 years) 84 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Human papillomavirus )17 )17$FSWBSJY )17(BSEBTJM Give IM .JOJNVNJOUFSWBMTCFUXFFOEPTFTXLT CFUXFFOBOEXLTCFUXFFO BOE0WFSBMMUIFSFNVTUCFBUMFBTU XLTCFUXFFOEPTFTBOE*GQPT TJCMFVTFUIFTBNFWBDDJOFQSPEVDUGPS BMMEPTFT Contraindication 1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPSUPBOZPGJUT DPNQPOFOUT Precautions t.PEFSBUFPSTFWFSFBDVUFJMMOFTT t*GQSFWJPVTMZWBDDJOBUFEXJUI.147 Meningococcal t(JWF.$7SPVUJOFMZBUBHFUISPVHIZSTBOEBCPPTUFSEPTFBU BHFZST PS.$7BOESJTLPGNFOJOHPDPD conjugate, DBMEJTFBTFQFSTJTUTSFWBDDJOBUFXJUI quadrivalent t(JWF.$7UPBMMVOWBDDJOBUFEUFFOTBHFUISPVHIZSTJGWBDDJOBUFE .$7JOZSTJGQSFWJPVTEPTFHJWFO .$7 BUBHFoZSTHJWFCPPTUFSEPTFBUBHFoZST Give IM t(JWFJOJUJBMEPTFUPVOWBDDJOBUFEGJSTUZFBSDPMMFHFTUVEFOUTBHFoZST XIFOZPVOHFSUIBOBHFZST PSJOZST JGQSFWJPVTEPTFHJWFOBUBHFZSTPS XIPMJWFJOSFTJEFODFIBMMTHJWFCPPTUFSEPTFJGNPTUSFDFOUEPTFHJWFO PMEFS 5IFOHJWFBEEJUJPOBMCPPTUFS XIFOZPVOHFSUIBOBHFZST Meningococcal EPTFTFWFSZZSTJGSJTLDPOUJOVFT polysaccharide t(JWF.$7%.FOBDUSB UPDIJMESFOBHFUISPVHINXIPIBWFQFS TJTUFOUDPNQMFNFOUDPNQPOFOUEFGJDJFODZBSFBSFTJEFOUPGPSUSBWFMJOHUP t8IFOBENJOJTUFSJOH.$7UPDIJMESFO .147 BDPVOUSZXJUIIZQFSFOEFNJDPSFQJEFNJDEJTFBTFPSBSFQSFTFOUEVSJOH XJUI)*7JOGFDUJPOHJWFJOJUJBMEPTFT Give SC PVUCSFBLTDBVTFECZBWBDDJOFTFSPHSPVQHJWFEPTFTNBQBSUPSOP TFQBSBUFECZXLT TPPOFSUIBOXLTBQBSU t(JWFFJUIFSCSBOEPG.$7UPVOWBDDJOBUFEDIJMESFOBHFNBOEPMEFS XJUIQFSTJTUFOUDPNQMFNFOUDPNQPOFOUEFGJDJFODZPSBOBUPNJDPSGVOD UJPOBMBTQMFOJBHJWFEPTFTNBQBSU*G.$7%.FOBDUSB JTHJWFOJU NVTUCFTFQBSBUFECZXLTGSPNUIFGJOBMEPTFPG1$7 Give IM t(JWFEPTFTFSJFTPGFJUIFS)17PS)17UPHJSMTBOEEPTFTFSJFTPG )17UPCPZTBUBHFoZSTPOBoNTDIFEVMF.BZCFHJWFOBT FBSMZBTBHFZST t(JWFBEPTFTFSJFTPGFJUIFS)17PS)17UPBMMPMEFSHJSMTXPNFO UISPVHIBHFZST BOEEPTFTFSJFTPG)17UPBMMPMEFSCPZTNFO UISPVHIBHFZST XIPXFSFOPUQSFWJPVTMZWBDDJOBUFE Contraindication 1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPSUPBOZPGJUT DPNQPOFOUT Precautions t.PEFSBUFPSTFWFSFBDVUFJMMOFTT t1SFHOBODZ t.JOJNVNJOUFSWBMCFUXFFOEPTFTJTN t$IJMESFOXIPBSFOPUGVMMZWBDDJOBUFE CZBHFZSTDBOCFWBDDJOBUFEBUTVCTF RVFOUWJTJUT t$POTJEFSSPVUJOFWBDDJOBUJPOPG DIJMESFOBHFZSTBOEPMEFSJOBSFBT XJUIOPFYJTUJOHQSPHSBN t(JWFEPTFBTQPTUFYQPTVSF QSPQIZMBYJTUPJODPNQMFUFMZWBDDJOBUFE DIJMESFOBHFNBOEPMEFSXIPIBWF SFDFOUMZEVSJOHUIFQBTUXLT CFFO FYQPTFEUPIFQBUJUJT"WJSVT t(JWFEPTFTTQBDFEUPNBQBSUUPBMMDIJMESFOBUBHFZSoN t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epatitis A )FQ" Give orally Contraindication 1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPSUPBOZPGJUT DPNQPOFOUT Precautions t.PEFSBUFPSTFWFSFBDVUFJMMOFTT t1SFHOBODZ 1/12 Note: Use MPSV4 ONLY if there is a permanent contraindication or precaution to MCV4. Contraindications t1SFWJPVTBOBQIZMBYJTUPUIJTWBDDJOFPSUPBOZPGJUT DPNQPOFOUT*GBMMFSHZUPMBUFYVTF37 t)JTUPSZPGJOUVTTVTDFQUJPO t%JBHOPTJTPGTFWFSFDPNCJOFEJNNVOPEFGJDJFODZ4$*% Precautions t.PEFSBUFPSTFWFSFBDVUFJMMOFTT t"MUFSFEJNNVOPDPNQFUFODFPUIFSUIBO4$*% t$ISPOJDHBTUSPJOUFTUJOBMEJTFBTF t4QJOBCJGJEBPSCMBEEFSFYTUSPQIZ t%POPUCFHJOTFSJFTJOJOGBOUTPMEFS UIBOBHFXLTEBZT t*OUFSWBMTCFUXFFOEPTFTNBZCFBT TIPSUBTXLT t*GQSJPSWBDDJOBUJPOJODMVEFEVTFPG EJGGFSFOUPSVOLOPXOCSBOET BUPUBM PGEPTFTTIPVMECFHJWFO t3PUBSJY37 HJWFBUBHFNN t3PUB5FR37 HJWFBUBHFNNN t.BZHJWFEPTFBTFBSMZBTBHFXLT t(JWFGJOBMEPTFOPMBUFSUIBOBHFNEBZT Rotavirus 37 Contraindications and precautions NJMEJMMOFTTJTOPUBDPOUSBJOEJDBUJPO Schedule for routine vaccination and other guidelines BOZWBDDJOFDBOCFHJWFOXJUIBOPUIFS (Page 4 of 4) Schedule for catch-up vaccination and related issues Vaccine name and route Summary of Recommendations for Child/Teen Immunization (Ages birth through 18 years) July 2011, Minnesota Department of Health Got Your Shots? 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MBCPSBUPSZ FWJ EFODF PG JNNVOJUZ PS EPDVNFOUBUJPO PG B EPTF HJWFO PO PS BGUFS UIF GJSTU CJSUIEBZ t1FPQMF JO IJHISJTL HSPVQT TVDI BT IFBMUIDBSF QFSTPOOFM QBJE VO QBJE PS WPMVOUFFS TUVEFOUT FOUFSJOH DPMMFHF BOE PUIFS QPTUoIJHI TDIPPM FEVDBUJPOBM JOTUJUVUJPOT BOE JOUFSOBUJPOBM USBWFMFST TIPVME SFDFJWF B UPUBM PG EPTFT t1FPQMF CPSO CFGPSF BSF VTVBMMZ DPOTJEFSFE JNNVOF CVU FWJEFODF PG JNNVOJUZ TFSPMPHZ PS EPDVNFOUFE IJTUPSZ PG EPTFT PG ..3 TIPVME CF DPOTJEFSFE GPS IFBMUIDBSF QFSTPOOFM t8PNFO PG DIJMECFBSJOH BHF XIP EP OPU IBWF BDDFQUBCMF FWJEFODF PG SVCFMMB JNNVOJUZ PS WBDDJOBUJPO People for whom vaccination is recommended Summary of Recommendations for Adult Immunization (Age 19 years & older) July 2011, Minnesota Department of Health Got Your Shots? 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QPMZTBDDIBSJEF t'JSTU ZFBS DPMMFHF TUVEFOUT UISPVHI BHF ZST XIP MJWF JO SFTJ EFODF IBMMT TFF UI CVMMFU JO UIF CPY UP UIF SJHIU GPS EFUBJMT WBDDJOF .147 Give IM M Human papillomavirus (HPV) )17 $FSWBSJY )17 (BSEBTJM Vaccine name and route Summary of Recommendations for Adult Immunization (Age 19 years & older) Front Back Perinatal Hepatitis B Prevention Pocket Guide Management of Pregnant Women Prenatal HBsAg Testing Test ALL pregnant women within first trimester of EACH pregnancy, even if tested before or had hepatitis B vaccines. Send copy of lab report with the HBsAg-positive results to the hospital of delivery and the infant’s healthcare provider. Report to MDH all HBsAg-positive women within one working day of knowledge of the pregnancy. Refer for or provide HBsAg-positive women counseling and medical management. Give the following information: 9 Modes of hepatitis transmission. 9 Perinatal concerns (i.e. HBsAg-positive mothers may breastfeed, treatment of newborns for exposure to hepatitis B). 9 Prevention of HBV to contacts, include vaccine prophylaxis for infant(s) and testing and/or hepatitis B vaccination for household, sexual, and needle-sharing contacts. 9 Substance abuse treatment and/or mental healthcare if appropriate. 9 Medical evaluation and possible treatment of chronic hepatitis B. Management of Delivery and Infant At admission for delivery: Review HBsAg status of all pregnant women. Perform HBsAg testing as soon as possible on women who: 9 do not have a documented HBsAg test result, 9 were at risk for HBV infection during pregnancy, or 9 had clinical hepatitis since previous testing. Retest HBsAg-negative women (at time of hospital delivery) with high-risk behaviors for infection: 9 Injection-drug use, 9 More than one sex partner in 6 months, 9 HBsAg-positive sexual partner, 9 Evaluation or treatment for sexually transmitted disease (STD), 9 Exhibits clinical hepatitis symptoms. Place copy of maternal HBsAg results on labor/delivery record, infant’s delivery summary, and nursery medical record. After delivery: ALL infants If mother’s Also give infant: should receive: HBsAg status is: Positive HBIG within 12 hours of birth Hep B vaccine within Negative No HBIG needed 12 hours Give HBIG if test positive Unknown of birth (at discharge) Must be given within 7 days of birth Minnesota Immunization Program 1-800-657-3970 Preterm infants weighing less than 2,000g: 9 Born to HBsAg-positive mothers: give hep B vaccine and HBIG within 12 hours of birth. 9 Born to HBsAg-negative mothers: give first dose of hep B vaccine at one month of age. 9 Born to mothers whose HBsAg status is unknown: give hep B vaccine and HBIG within 12 hours of birth. For HBsAg-positive mothers and mothers whose HBsAg status is unknown at time of discharge 9 Fax “Hospital Report Form” to MDH within 1 working day of infant’s birth. 9 Alert infant’s pediatric provider. Record date and time vaccines were given on infant’s record. Case Management of Infants Born to HBsAg-positive Mothers Completion of hep B vaccine series at 1-2 months and 6 months of age (using monovalent vaccine). If using a combination hep B vaccine (e.g. Hib-hep B or DTaPIPV-hep B), final dose should NOT be administered before age 24 weeks (164 days). Administration of 4 doses of hep B vaccine is permissible when giving combination vaccines after the birth dose. Report all vaccine dates to local and/or state health departments. Perform post-vaccination serology at 12 months of age. (No earlier than 9 months of age.) Test for both HBsAg and anti-HBs. Report test results to local and/or state health department. Interpretation of Serology Results Result Follow-up needed Anti-HBs positive None. Infant is protected. HBsAg-negative No response. Infant is susceptible to infection. 3 doses of hep B vaccine series as soon as Anti-HBs negative Repeat possible. Schedule of 0,1,4 months. Recheck HBsAg-negative serology 4-6 weeks after last dose. Monovalent hepatitis B vaccine must be used for second series. Anti-HBs negative Infant infected with hepatitis B. Needs regular HBsAg-positive check-ups and liver function tests. Remember to report HBsAg-positive test results to local and/or state health department. Immunization Program P.O. Box 64975 St. Paul, MN, 55164-0975 651-201-5503 or 800-657-3970 www.health.state.mn.us/immunize 1/08 IC#141-1687 Available on the web at: www.health.state.mn.us/divs/idepc/diseases/hepb/perinatal/pocket.htmll July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 89 Front Back Pneumococcal Vaccination Pocket Guide Algorithm for (re)vaccinating persons age 65 years or older Has the person been vaccinated previously? Pneumococcal polysaccharide vaccine (PPSV) is indicated for persons age 65 years or older, or age 2 through 64 years with any of the following: • Chronic cardiovascular disease (e.g., CHF, cardiomyopathies) • Chronic pulmonary disease (e.g., emphysema or COPD, including asthma) • Cigarette smokers age 19 through 64 years • Chronic liver disease, including persons with long-term alcoholism • Diabetes mellitus • CSF leaks • Functional or anatomic asplenia (e.g. sickle cell disease or splenectomy) • Immunosuppressive conditions (e.g., HIV infection, leukemia, congenital immunodeficiency, Hodgkin’s disease, lymphoma, multiple myeloma, or generalized malignancy) • Organ or bone marrow transplantation • Therapy with alkylating agents, antimetabolites, or systemic corticosteroids • Chronic renal failure or nephrotic syndrome • Cochlear implants Was the person age 65 years or older at the time of last vaccination? Yes No Have 5 or more years elapsed since the first dose? Yes Vaccination not indicated No WHO GETS A SECOND DOSE OF PPSV? A maximum of two PPSV doses in a lifetime is all that is recommended. A second dose is indicated for persons: • Age 2 through 64 years with any of the following: functional or anatomic asplenia, immunosuppression, transplant, chronic renal failure, nephrotic syndrome. • Age 65 years or older who received the first dose prior to age 65 years. AGE OF PATIENT: SPACING BETWEEN SHOTS: Age 2 through 9 years Age 10 through 64 years Age 65 years or older 3 years apart At least 5 years apart At least 5 years apart TALKING POINTS WITH PATIENTS CONTRAINDICATIONS AND PRECAUTIONS Previous anaphylactic reaction to PPSV or any of its components Moderate to severe illness • • UNKNOWN HISTORY • Make a reasonable effort to obtain a vaccination history. When in doubt, vaccinate. The risks of invasive pneumococcal disease outweigh the risks of revaccination. • VACCINE ADMINISTRATION • • Administer 0.5 ml PPSV intramuscularly (IM) or subcutaneously (SC): • IM: 1 - 1.5” 22-25 gauge needle OR • SC: 5/8” 23-25 gauge needle • Children age 2 years or older at risk for invasive pneumococcal disease need PPSV. It should be separated by 8 weeks from a dose of PCV. Minnesota Immunization Program (Re)vaccination indicated Yes INDICATIONS • • No or unsure • • • Most pneumococcal deaths are in people age 65 or older. Flu and its most common complication, pneumonia, are the sixth leading cause of death in Minnesota. PPSV is 60-70% effective in preventing most strains of pneumonia from spreading to the blood (bacteremia) or brain (meningitis) Immunization can prevent prolonged hospitalization or death due to invasive pneumococcal disease. The vaccine is important because pneumococcal disease is increasingly drug-resistant and hard to treat. Medicare Part B and most health plans pay for the vaccine. The vaccine is safe; the most common side effect is a sore arm lasting 24-48 hours. PPSV can be given at any time during the year. It’s okay to get this shot at the same time as the flu shot or any other vaccine. 1-800-657-3970 IC# 141-0837 (MDH, 12/2009) Available on the web at: www.health.state.mn.us/divs/idepc/diseases/pneumococcal/hcp/pocket.html 90 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Front Back Pregnancy and Vaccination Pregnant women may be at risk for infectious diseases and their complications. Consider vaccination - even during pregnancy - to protect the woman and the fetus. Recommended Vaccine Contraindicated BEFORE pregnancy If at risk DURING pregnancy Hepatitis A (HepA) If at risk Hepatitis B (HepB) If indicated Human Papillomavirus (HPV) Age 9 through 26 years Influenza (TIV) Contraindicated, under study Avoid conception for 4 weeks Measles, Mumps, Rubella (MMR) Avoid conception for 4 weeks Avoid conception for 4 weeks Contraindicated Give immediately postpartum if susceptible to rubella If indicated Pneumococcal (PPSV) If indicated Tetanus, Diphtheria (Td) Varicella (VAR) Age 9 through 26 years Contraindicated Meningococcal (MCV) one dose only AFTER pregnancy 1 dose annually Influenza (LAIV) Tetanus, Diphtheria, Pertussis (Tdap) If indicated Preferred If at risk of pertussis,otherwise Td preferred Preferred Tdap preferred If indicated Tdap preferred Avoid conception for 4 weeks Contraindicated Give immediately postpartum if susceptible MDH Immunization Program Considerations Recommended - Vaccine is recommended regardless of pregnancy. Contraindicated - Vaccine is contraindicated for pregnant women because of the theoretical risk of transmission of the vaccine virus to the fetus. If at risk - Certain vaccines have limited data regarding administration and pregnancy. Only consider these vaccines for pregnant women if there is a risk of exposure and subsequent disease (e.g., community outbreak). If indicated - Certain vaccines are indicted based on patient risk factors (e.g., medical, occupational, lifestyle, international travel) and should be given if susceptible regardless of pregnancy. Td/Tdap • If last Td vaccination was 10 or more years ago, give Td during the second or third trimester. • If last Td vaccination was within the past 10 years, give Tdap during the immediate postpartum period. • In a pertussis outbreak Td can be deferred during pregnancy and Tdap substituted in the immediate postpartum period, or Tdap can be given instead of Td after discussing the risks and benefits with the pregnant woman. • Give Tdap to household contacts and caregivers to protect the newborn. Vaccine-related prenatal serologic screening • Test for rubella: if susceptible, vaccinate postpartum. • Test for hepatitis B: vaccinate if susceptible and at risk. Send results to birthing hospital; if HBsAg-positive, report results to the Minnesota Department of Health. Vaccinating household contacts of pregnant women • Household contacts of pregnant women should receive Tdap and influenza vaccines, as well as hepatitis B (if pregnant woman is HBsAgpositive). • No vaccine - except smallpox - is contraindicated for household contacts or the children of a pregnant woman. Vaccinating breast-feeding women • Neither inactivated nor live-virus vaccines given to a breast-feeding woman affects the safety of breast-feeding for mothers or infants. − Most live-virus vaccines are not secreted in breast milk; however, if this does occur (i.e., with attenuated rubella vaccination) it produces asymptomatic infection in infants. • Breast-feeding does not adversely affect immunization and is not a contraindication for any vaccine - except smallpox. Vaccinating newborns • Stress the importance of vaccinating newborns, starting with the hepatitis B birth dose. 1-800-657-3970 IC# 141-3140 (12/10) Available to order from the Minnesota Immunization Program, 1-800-657-3970. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 91 92 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Morbidity and Mortality Weekly Report Recommendations and Reports / Vol. 60 / No. 2 January 28, 2011 General Recommendations on Immunization Recommendations of the Advisory Committee on Immunization Practices (ACIP) Table 1: Recommended andExamination minimum available ages and intervals between vaccine doses. Continuing Education at http://www.cdc.gov/mmwr/cme/conted.html Table 3: Guidelines for spacing of live and inactivated antigens. Table 4: Guidelines for administering antibody-containing products and vaccines. Table 5: Recommended intervals between administration of antibody-containing products and Department of Health and Human Services measles- or varicella-containing U.S. vaccine, by product and indication for vaccination. Centers for Disease Control and Prevention Table 13: Vaccination of persons with primary and secondary immunodeficiencies. Table 14: Approaches to evaluation and vaccination of persons vaccinated outside the United States who have no (or questionable) vaccination records. Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdfl July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 93 Recommendations and Reports TABLE 1. Recommended and minimum ages and intervals between vaccine doses*† Recommended age for this dose Vaccine and dose number HepB-1§ HepB-2 HepB-3¶ DTaP-1§ DTaP-2 DTaP-3 DTaP-4 DTaP-5 Hib-1§,§§ Hib-2 Hib-3¶¶ Hib-4 IPV-1§ IPV-2 IPV-3 IPV-4*** PCV-1§§ PCV-2 PCV-3 PCV-4 MMR-1††† MMR-2††† Varicella-1††† Varicella-2††† HepA-1 HepA-2 Influenza, inactivated¶¶¶ LAIV (intranasal)¶¶¶ MCV4-1†††† MCV4-2 MPSV4-1†††† MPSV4-2 Td Tdap§§§§ PPSV-1 PPSV-2¶¶¶¶ HPV-1***** HPV-2 HPV-3††††† Rotavirus-1§§§§§ Rotavirus-2 Rotavirus-3¶¶¶¶¶ Herpes zoster****** Birth 1–2 months 6–18 months 2 months 4 months 6 months 15–18 months 4–6 years 2 months 4 months 6 months 12–15 months 2 months 4 months 6–18 months 4–6 years 2 months 4 months 6 months 12–15 months 12–15 months 4–6 years 12–15 months 4–6 years 12–23 months ≥18 months ≥6 months 2–49 years 11–12 years 16 years — — 11–12 years ≥11 years — — 11–12 years 11–12 years (+2 months) 11–12 years (+6 months) 2 months 4 months 6 months ≥60 years Minimum age for this dose Birth 4 weeks 24 weeks 6 weeks 10 weeks 14 weeks 12 months 4 years 6 weeks 10 weeks 14 weeks 12 months 6 weeks 10 weeks 14 weeks 4 years 6 weeks 10 weeks 14 weeks 12 months 12 months 13 months 12 months 15 months 12 months 18 months 6 months**** 2 years 2 years 11 years (+8 weeks) 2 years 7 years 7 years 7 years 2 years 7 years 9 years 9 years (+4 weeks) 9 years (+24 weeks) 6 weeks 10 weeks 14 weeks 60 years Recommended interval to next dose 1–4 months 2–17 months — 2 months 2 months 6–12 months 3 years — 2 months 2 months 6–9 months — 2 months 2–14 months 3–5 years — 8 weeks 8 weeks 6 months — 3–5 years — 3–5 years — 6–18 months** — 1 month 1 month 5 years — 5 years — 10 years — 5 years — 2 months 4 months — 2 months 2 months — — Minimum interval to next dose 4 weeks 8 weeks — 4 weeks 4 weeks 6 months**,†† 6 months** — 4 weeks 4 weeks 8 weeks — 4 weeks 4 weeks 6 months — 4 weeks 4 weeks 8 weeks — 4 weeks — 12 weeks§§§ — 6 months** — 4 weeks 4 weeks 8 weeks — 5 years — 5 years — 5 years — 4 weeks 12 weeks††††† — 4 weeks 4 weeks — — See table footnotes on page 37 36 MMWR / January 28, 2011 / Vol. 60 / No. 2 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf 94 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Recommendations and Reports TABLE 1. (Continued) Recommended and minimum ages and intervals between vaccine doses*,† Abbreviations: DTaP = diphtheria and tetanus toxoids and acellular pertussis; HepA = hepatitis A; HepB = hepatitis B; Hib = Haemophilus influenzae type b; HPV = human papillomavirus; IPV = inactivated poliovirus; LAIV = live, attenuated influenza vaccine; MCV4 = quadrivalent meningococcal conjugate vaccine; MMR = measles, mumps, and rubella; MMRV = measles, mumps, rubella, and varicella; MPSV4 = quadrivalent meningococcal polysaccharide vaccine; PCV = pneumococcal conjugate vaccine; PPSV = pneumococcal polysaccharide vaccine; PRP-OMB = polyribosylribitol phosphate-meningococcal outer membrane protein conjugate; Td = tetanus and diphtheria toxoids; TIV = trivalent inactiated influenza vaccine; Tdap = tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis; Var = varicella vaccine. * Combination vaccines are available. Use of licensed combination vaccines is generally preferred to separate injections of their equivalent component vaccines. When administering combination vaccines, the minimum age for administration is the oldest age for any of the individual components; the minimum interval between doses is equal to the greatest interval of any of the individual components. † Information on travel vaccines, including typhoid, Japanese encephalitis, and yellow fever, is available at http://www.cdc.gov/travel. Information on other vaccines that are licensed in the United States but not distributed, including anthrax and smallpox, is available at http://www.bt.cdc.gov. § Combination vaccines containing the hepatitis B component are available (see Table 2). These vaccines should not be administered to infants aged <6 weeks because of the other components (i.e., Hib, DTaP, HepA, and IPV). ¶ HepB-3 should be administered at least 8 weeks after HepB-2 and at least 16 weeks after HepB-1 and should not be administered before age 24 weeks. ** Calendar months. †† The minimum recommended interval between DTaP-3 and DTaP-4 is 6 months. However, DTaP-4 need not be repeated if administered at least 4 months after DTaP-3. §§ For Hib and PCV, children receiving the first dose of vaccine at age ≥7 months require fewer doses to complete the series. ¶¶ If PRP-OMP (Pedvax-Hib, Merck Vaccine Division) was administered at ages 2 and 4 months, a dose at age 6 months is not necessary. *** A fourth dose is not needed if the third dose was administered at ≥4 years and at least 6 months after the previous dose. ††† Combination MMRV vaccine can be used for children aged 12 months–12 years. See text for details. §§§ The minimum interval from Varicella-1 to Varicella-2 for persons beginning the series at age ≥13 years is 4 weeks. ¶¶¶ One dose of influenza vaccine per season is recommended for most persons. Children aged <9 years who are receiving influenza vaccine for the first time or who received only 1 dose the previous season (if it was their first vaccination season) should receive 2 doses this season. **** The minimum age for inactivated influenza vaccine varies by vaccine manufacturer. See package insert for vaccine-specific minimum ages. †††† Revaccination with meningococcal vaccine is recommended for previously vaccinated persons who remain at high risk for meningococcal disease. (Source: CDC. Updated recommendations from the Advisory Committee on Immunization Practices (ACIP) for revaccination of persons at prolonged increased risk for meningococcal disease. MMWR 2009;58:[1042–3]). §§§§ Only 1 dose of Tdap is recommended. Subsequent doses should be given as Td. For one brand of Tdap, the minimum age is 11 years. For management of a tetanus-prone wound in persons who have received a primary series of tetanus-toxoid–containing vaccine, the minimum interval after a previous dose of any tetanus-containing vaccine is 5 years. ¶¶¶¶ A second dose of PPSV 5 years after the first dose is is recommended for persons aged ≤65 years at highest risk for serious pneumococcal infection and those who are likely to have a rapid decline in pneumococcal antibody concentration. (Source: CDC. Prevention of pneumococcal disease: recommendations of the Advisory Committee on Immunization Practices [ACIP]. MMWR 1997;46[No. RR-8]). ***** Bivalent HPV vaccine is approved for females aged 10–25 years. Quadrivalent HPV vaccine is approved for males and females aged 9–26 years. ††††† The minimum age for HPV-3 is based on the baseline minimum age for the first dose (i.e., 108 months) and the minimum interval of 24 weeks between the first and third dose. Dose 3 need not be repeated if it is administered at least 16 weeks after the first dose. §§§§§ The first dose of rotavirus must be administered at age 6 weeks through 14 weeks and 6 days. The vaccine series should not be started for infants aged ≥15 weeks, 0 days. Rotavirus should not be administered to children older than 8 months, 0 days of age regardless of the number of doses received between 6 weeks and 8 months, 0 days of age. ¶¶¶¶¶ If 2 doses of Rotarix (GlaxoSmithKline) are administered as age appropriate, a third dose is not necessary. ****** Herpes zoster vaccine is recommended as a single dose for persons aged ≥60 years. TABLE 2. FDA-licensed combination vaccines* Vaccine† Hib-HepB DTaP/Hib HepA-HepB DTaP-HepB-IPV MMRV DTaP-IPV DTaP-IPV/Hib Trade name (year licensed) Age range Comvax (1996) TriHIBit (1996) Twinrix (2001) Pediarix (2002) ProQuad (2005) Kinrix (2008) Pentacel (2008) 6 weeks–71 months 15–18 months ≥18 years 6 weeks–6 years 12 months–12 years 4–6 years 6 weeks–4 years Routinely recommended ages Three-dose schedule at 2, 4, and 12–15 months of age Fourth dose of Hib and DTaP series Three doses on a schedule of 0, 1, and 6 months Three-dose series at 2, 4 and 6 months of age Two doses, the first at 12–15 months, the second at 4–6 years Fifth dose of DTaP and fourth dose of IPV Four-dose schedule at 2, 4, 6, and 15–18 months of age Abbreviations: DT = diphtheria and tetanus toxoids; DTaP = diphtheria and tetanus toxoids and acellular pertussis; FDA = Food and Drug Administration; HepA = hepatitis A; HepB = hepatitis B; Hib = Haemophilus influenzae type b; IPV = inactivated poliovirus; MMR = measles, mumps, and rubella; MMRV = measles, mumps, rubella, and varicella; Td = tetanus and diphtheria toxoids; Tdap = tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis. Source: American Academy of Pediatrics. Passive immunization. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS, eds. Red book: 2009 report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009. * Although MMR, DTaP, DT, Td, and Tdap are combination vaccines, they are not included on this list because they are not available in the United States as single-antigen products. † A dash ( - ) between vaccine products indicates that products are supplied in their final form by the manufacturer and do not require mixing or reconstitution by the user. A slash ( / ) indicates that the products must be mixed or reconstituted by the user. MMWR / January 28, 2011 / Vol. 60 / No. 2 37 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 95 Recommendations and Reports TABLE 3. Guidelines for spacing of live and inactivated antigens Antigen combination Recommended minimum interval between doses Two or more inactivated* Inactivated and live Two or more live injectable† May be administered simultaneously or at any interval between doses May be administered simultaneously or at any interval between doses 28 days minimum interval, if not administered simultaneously Source: American Academy of Pediatrics. Pertussis. In: Pickering LK, Baker, CJ, Kimberlin DW, Long SS, eds. Red book: 2009 report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009:22. * Certain experts suggest a 28-day interval between tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine and tetravalent meningococcal conjugate vaccine if they are not administered simultaneously. † Live oral vaccines (e.g., Ty21a typhoid vaccine and rotavirus vaccine) may be administered simultaneously or at any interval before or after inactivated or live injectable vaccines. TABLE 4. Guidelines for administering antibody-containing products* and vaccines Type of administration Simultaneous (during the same office visit) Nonsimultaneous Products administered Recommended minimum interval between doses Antibody-containing products and inactivated antigen Can be administered simultaneously at different anatomic sites or at any time interval between doses Antibody-containing products and live antigen Should not be administered simultaneously.† If simultaneous administration of measles-containing vaccine or varicella vaccine is unavoidable, administer at different sites and revaccinate or test for seroconversion after the recommended interval (see Table 5) Administered first Antibody-containing products Inactivated antigen Antibody-containing products Live antigen Administered second Inactivated antigen Antibody-containing products Live antigen Antibody-containing products No interval necessary No interval necessary Dose related†,§ 2 weeks† * Blood products containing substantial amounts of immune globulin include intramuscular and intravenous immune globulin, specific hyperimmune globulin (e.g., hepatitis B immune globulin, tetanus immune globulin, varicella zoster immune globulin, and rabies immune globulin), whole blood, packed red blood cells, plasma, and platelet products. † Yellow fever vaccine; rotavirus vaccine; oral Ty21a typhoid vaccine; live, attenuated influenza vaccine; and zoster vaccine are exceptions to these recommendations. These live, attenuated vaccines can be administered at any time before or after or simultaneously with an antibody-containing product. § The duration of interference of antibody-containing products with the immune response to the measles component of measles-containing vaccine, and possibly varicella vaccine, is dose related (see Table 5). 38 MMWR / January 28, 2011 / Vol. 60 / No. 2 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf 96 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Recommendations and Reports TABLE 5. Recommended intervals between administration of antibody-containing products and measles- or varicella-containing vaccine, by product and indication for vaccination Product/Indication Dose (mg IgG/kg) and route* Tetanus IG Hepatitis A IG Contact prophylaxis International travel Hepatitis B IG Rabies IG Varicella IG Measles prophylaxis IG Standard (i.e., nonimmunocompromised) contact Immunocompromised contact Blood transfusion RBCs, washed RBCs, adenine-saline added Packed RBCs (hematocrit 65%)§ Whole blood (hematocrit 35%–50%)§ Plasma/platelet products Cytomegalovirus IGIV IGIV Replacement therapy for immune deficiencies¶ Immune thrombocytopenic purpura treatment Postexposure varicella prophylaxis** Immune thrombocytopenic purpura treatment Kawasaki disease Monoclonal antibody to respiratory syncytial virus F protein (Synagis [MedImmune])†† Recommended interval before measles- or varicella-containing vaccine† administration (months) 250 units (10 mg IgG/kg) IM 3 0.02 mL/kg (3.3 mg IgG/kg) IM 0.06 mL/kg (10 mg IgG/kg) IM 0.06 mL/kg (10 mg IgG/kg) IM 20 IU/kg (22 mg IgG/kg) IM 125 units/10 kg (60–200 mg IgG/kg) IM, maximum 625 units 3 3 3 4 5 0.25 mL/kg (40 mg IgG/kg) IM 0.50 mL/kg (80 mg IgG/kg) IM 5 6 10 mL/kg, negligible IgG/kg IV 10 mL/kg (10 mg IgG/kg) IV 10 mL/kg (60 mg IgG/kg) IV 10 mL/kg (80–100 mg IgG/kg) IV 10 mL/kg (160 mg IgG/kg) IV 150 mg/kg maximum None 3 6 6 7 6 300–400 mg/kg IV¶ 400 mg/kg IV 400 mg/kg IV 1000 mg/kg IV 2 g/kg IV 15 mg/kg IM 8 8 8 10 11 None Abbreviations: HIV = human immunodeficiency virus; IG = immune globulin; IgG = immune globulin G; IGIV = intravenous immune globulin; mg IgG/kg = milligrams of immune globulin G per kilogram of body weight; IM = intramuscular; IV = intravenous; RBCs = red blood cells. * This table is not intended for determining the correct indications and dosages for using antibody-containing products. Unvaccinated persons might not be protected fully against measles during the entire recommended interval, and additional doses of IG or measles vaccine might be indicated after measles exposure. Concentrations of measles antibody in an IG preparation can vary by manufacturer’s lot. Rates of antibody clearance after receipt of an IG preparation also might vary. Recommended intervals are extrapolated from an estimated half-life of 30 days for passively acquired antibody and an observed interference with the immune response to measles vaccine for 5 months after a dose of 80 mg IgG/kg. † Does not include zoster vaccine. Zoster vaccine may be given with antibody-containing blood products. § Assumes a serum IgG concentration of 16 mg/mL. ¶ Measles and varicella vaccinations are recommended for children with asymptomatic or mildly symptomatic HIV infection but are contraindicated for persons with severe immunosuppression from HIV or any other immunosuppressive disorder. ** The investigational VariZIG, similar to licensed varicella-zoster IG (VZIG), is a purified human IG preparation made from plasma containing high levels of antivaricella antibodies (IgG). The interval between VariZIG and varicella vaccine (Var or MMRV) is 5 months. †† Contains antibody only to respiratory syncytial virus MMWR / January 28, 2011 / Vol. 60 / No. 2 39 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 97 Recommendations and Reports TABLE 13. Vaccination of persons with primary and secondary immunodeficiencies Primary Specific immunodeficiency Contraindicated vaccines* Risk-specific recommended vaccines* Effectiveness and comments Severe antibody deficiencies (e.g., X-linked agammaglobulinemia and common variable immunodeficiency) OPV† Smallpox LAIV BCG Ty21a (live typhoid) Yellow fever Less severe antibody deficiencies (e.g., selective IgA deficiency and IgG subclass deficiency Pneumococcal OPV† BCG Yellow fever Other live vaccines appear to be safe. All vaccines likely effective; immune response might be attenuated. Complete defects (e.g., severe combined immunodeficiency [SCID] disease, complete DiGeorge syndrome) All live vaccines§,¶,** Pneumococcal Vaccines might be ineffective. Partial defects (e.g., most patients with DiGeorge syndrome, Wiskott-Aldrich syndrome, ataxia- telangiectasia) All live vaccines§,¶,** Pneumococcal Meningococcal Hib (if not administered in infancy) Effectiveness of any vaccine depends on degree of immune suppression. Complement Persistent complement, properdin, or factor B deficiency None Pneumococcal Meningococcal All routine vaccines likely effective. Phagocytic function Chronic granulomatous disease, leukocyte adhesion defect, and myeloperoxidase deficiency. Live bacterial vaccines§ Pneumococcal†† All inactivated vaccines safe and likely effective. Live viral vaccines likely safe and effective. Secondary HIV/AIDS OPV† Smallpox BCG LAIV Withhold MMR and varicella in severely immunocompromised persons. Yellow fever vaccine might have a contraindication or a precaution depending on clinical parameters of immune function*** Pneumococcal Consider Hib (if not administered in infancy) and meningococcal vaccination. MMR, varicella, rotavirus, and all inactivated vaccines, including inactivated influenza, might be effective.§§ Malignant neoplasm, transplantation, immunosuppressive or radiation therapy Live viral and bacterial, depending on immune status§,¶ Pneumococcal Effectiveness of any vaccine depends on degree of immune suppression. Asplenia None Pneumococcal Meningococcal Hib (if not administered in infancy) All routine vaccines likely effective. Chronic renal disease LAIV Pneumococcal Hepatitis B¶¶ All routine vaccines likely effective. B-lymphocyte (humoral) T-lymphocyte (cell-mediated and humoral) Pneumococcal Consider measles and varicella vaccination The effectiveness of any vaccine is uncertain if it depends only on the humoral response (e.g., PPSV or MPSV4). IGIV interferes with the immune response to measles vaccine and possibly varicella vaccine. Abbreviations: AIDS = acquired immunodeficiency syndrome; BCG = bacille Calmette-Guérin; Hib = Haemophilus influenzae type b; HIV = human immunodeficiency virus; IG = immunoglobulin; IGIV = immune globulin intravenous; LAIV = live, attenuated influenza vaccine; MMR = measles, mumps, and rubella; MPSV4 = quadrivalent meningococcal polysaccharide vaccine; OPV = oral poliovirus vaccine (live); PPSV = pneumococcal polysaccharide vaccine; TIV = trivalent inactivated influenza vaccine. Source: Adapted from American Academy of Pediatrics. Passive immunization. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS eds. Red book: 2009 report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009:74–5. * Other vaccines that are universally or routinely recommended should be given if not contraindicated. † OPV is no longer available in the United States. § Live bacterial vaccines: BCG and oral Ty21a Salmonella Typhi vaccine. ¶ Live viral vaccines: MMR, MMRV, OPV, LAIV, yellow fever, zoster, rotavirus, varicella, and vaccinia (smallpox). Smallpox vaccine is not recommended for children or the general public. ** Regarding T-lymphocyte immunodeficiency as a contraindication for rotavirus vaccine, data exist only for severe combined immunodeficiency. †† Pneumococcal vaccine is not indicated for children with chronic granulomatous disease beyond age-based universal recommendations for PCV. Children with chronic granulomatous disease are not at increased risk for pneumococcal disease. §§ HIV-infected children should receive IG after exposure to measles and may receive varicella and measles vaccine if CD4+ T-lymphocyte count is ≥15%. ¶¶ Indicated based on the risk from dialysis-based bloodborne transmission. *** Symptomatic HIV infection or CD4+ T-lymphocyte count of <200/mm3 or <15% of total lymphocytes for children aged <6 years is a contraindication to yellow fever vaccine administration. Asymptomatic HIV infection with CD4+ T-lymphocyte count of 200–499/mm3 for persons aged ≥6 years or 15%–24% of total lymphocytes for children aged <6 years is a precaution for yellow fever vaccine administration. Details of yellow fever vaccine recommendations are available from CDC. (CDC. Yellow fever vaccine: recommendations of the Advisory Committee on Immunization Practices [ACIP]. MMWR 2010;59[No. RR-7].) 48 MMWR / January 28, 2011 / Vol. 60 / No. 2 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf 98 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Recommendations and Reports TABLE 14. Approaches to evaluation and vaccination of persons vaccinated outside the United States who have no (or questionable) vaccination records Vaccine Recommended approach Alternative approach* MMR Revaccination with MMR Serologic testing for IgG antibodies to measles, mumps, and rubella Hib Age-appropriate revaccination Hepatitis A Age-appropriate revaccination Hepatitis B Age-appropriate revaccination and serologic testing for HBsAg† Poliovirus Revaccination with inactivated poliovirus vaccine Serologic testing for neutralizing antibody to poliovirus types 1, 2, and 3 (limited availability) DTaP Revaccination with DTaP, with serologic testing for specific IgG antibody to tetanus and diphtheria toxins in the event of a severe local reaction Persons whose records indicate receipt of ≥3 doses: serologic testing for specific IgG antibody to diphtheria and tetanus toxins before administering additional doses (see text), or administer a single booster dose of DTaP, followed by serological testing after 1 month for specific IgG antibody to diphtheria and tetanus toxins with revaccination as appropriate (see text) Tdap Age-appropriate vaccination of persons who are candidates for Tdap vaccine on the basis of time since last diphtheria and tetanus-toxoid–containing vaccines. — Varicella Age-appropriate vaccination of persons who lack evidence of varicella immunity — Pneumococcal conjugate Age-appropriate vaccination — Rotavirus Age-appropriate vaccination — HPV Age-appropriate vaccination — Zoster Age-appropriate vaccination — — Serologic testing for IgG antibodies to hepatitis A — Abbreviations: DTaP = diphtheria and tetanus toxoids and acellular pertussis; HBsAg = hepatitis B surface antigen; Hib = Haemophilus influenzae type b; HPV = human papillomavirus; IgG = immune globulin G; MMR = measles, mumps, and rubella; Tdap = tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis. * There is a recommended approach for all vaccines and an alternative approach for some vaccines. † In rare instances, hepatitis B vaccine can give a false-positive HBsAg result up to 18 days after vaccination; therefore, blood should be drawn to test for HBsAg before vaccinating (Source: CDC. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices [ACIP]; Part I: Immunization in Infants, Children, and Adolescents. MMWR 2005;54(No. RR-16.]) MMWR / January 28, 2011 / Vol. 60 / No. 2 49 Available on the web at: www.cdc.gov/mmwr/pdf/rr/rr6002.pdf July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 99 100 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 101 Contraindicated Contraindicated Recommended Recommended If indicated Contraindicated If indicated Recommended If Indicated - Vaccine is indicated based on specific risk factors or timing constraints. Recommended Recommended Kidney failure, end-stage renal disease, on hemodialysis If indicated Recommended Recommended If indicated If indicated Hematopoietic cell transplant recipients (HCT)4 No recommendation. Contraindicated - Vaccine is contraindicated based on the medical condition of the person. Recommended Recommended Asplenia including elective splenectomy and persistent complement component deficiency Recommended Recommended Recommended Recommended Recommended Recommended - Vaccine is recommended for all persons who meet the age requirements and who lack evidence of immunity (i.e., no documented vaccination or no evidence of prior infection, or no laboratory evidence of immunity). Varicella 13 Tetanus, diphtheria, pertussis Rotavirus12 polysaccharide11 Pneumococcal conjugate10 Pneumococcal ages 11-12 years conjugate9 ages 2-10 years Meningococcal conjugate9 Meningococcal Recommended Recommended Influenza 7 Recommended Recommended Inactivated poliovirus Measles, mumps, rubella 8 Recommended Recommended Human papillomavirus Hepatitis B 6 If indicated Non-severe immunosuppression Recommended Severe immunosuppression Hepatitis A immunodeficiency virus [HIV] infection) Diabetes, heart disease, chronic lung disease, chronic alcoholism, cochlear implants Recommended Prematurity HIV infection3 CD4+ T lymphocyte count Haemophilis Influenzae type b5 Vaccine 1 Altered Immunocompetence2 (excluding human Vaccines Indicated for Infants, Children, and Adolescents Based on Medical and Other Indications Vaccines Indicated for Infants, Children, and Adolescents Based on Medical and Other Indications Footnotes: 1. Prematurity yy Vaccinate premature infants, regardless of birth weight, at the same chronologic age and schedule as full-term infants, except for hepatitis B; see Hepatitis B footnote (#6). 2. Altered immunocompetence (excluding HIV) yy Includes congenital immunodeficiency, leukemia, lymphoma, generalized malignancy, or therapy with alkylating agents, antimetabolites, radiation, or a high dose, prolonged course of corticosteroids. yy Inactivated vaccines generally are acceptable, e.g., pneumococcal, meningococcal, and inactivated influenza vaccine. However, the immune response and efficacy may be reduced. yy Generally avoid live vaccines for persons with altered immunocompetence including immune deficiencies or immunocompromising conditions. 3. HIV infection ACIP and AAP define severe immunosuppression in HIV infected children as: yy CD4+ T-lymphocytes counts ○○less than 750 for children younger than 12 months, ○○less than 500 for children age 1 through 5 years, or ○○less than 200 for persons age 6 years or older; yy Or CD4+ T-lymphocytes constituting: ○○less than 15% of total lymphocytes for children younger than 13 years. 4. HCT recipients yy Begin revaccination at least 12 months after HCT. yy For live virus vaccines, MMR and varicella, begin revaccination at least 24 months after HCT; see MMR and varicella footnotes (#8 and #13). 5. Haemophilis Influenzae type b (Hib) yy Consider 1 dose for unvaccinated high-risk persons age 5 years and older with sickle cell disease, leukemia, or HIV infection, or who have had a splenectomy. 6. Hepatitis B (HepB) yy Give hepatitis B vaccine and immune globulin at birth to premature infants born to HBsAgpostive mothers. 102 www.health.state.mn.us/immunize yy Delay the first dose of hepatitis B vaccine to premature infants born to HBsAg-negative mothers until the infant weighs at least 2000 grams. 7. Influenza yy Give HCT recipients influenza vaccine 6 months or more after HCT, and annually thereafter. yy Give annually to all children age 6 months and older regardless of medical and other indications. yy Give 2 doses separated by at least 4 weeks to children younger than age 9 years who are receiving influenza vaccine for the first time or who were vaccinated for the first time last season and only received 1 dose. 8. Measles, mumps, rubella (MMR) yy Evaluation and testing of asymptomatic persons to identify HIV infection is not necessary before deciding to administer MMR or other measlescontaining vaccine. yy Severely immunosuppressed HIV-infected patients who are exposed to measles should receive immune globulin, regardless of prior vaccination status. yy Give 1 dose to HIV-infected children with non-severe immunosuppression (see #3) as soon as possible after their first birthday. The immunologic response to both live and killed antigen vaccines may decrease as HIV disease progresses; vaccination early in the course of HIV infection may be more likely to induce an immune response. ○○Consider giving the second dose of MMR vaccine as soon as 28 days after the first dose rather than waiting until the child is ready to enter kindergarten or first grade. yy Give 1 dose to HCT recipients 24 months after transplant and if the HCT recipient is presumed to be immunocompetent. yy Give 1 dose to all asymptomatic HIV-infected children without evidence of measles immunity. 9. Meningococcal conjugate (MCV) yy Give 2 doses 2 months apart to children age 2 years and older with persistent complement component deficiency, anatomic or functional asplenia, or HIV infection and 1 dose every 5 years thereafter. yy Give 1 dose of MCV to children who remain at risk and are: ○○Age 6 years and older who received MPSV or Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 MCV 3 or more years previously. ○○Age 7 years and older who received MPSV or MCV 5 or more years previously. 10.Pneumococcal conjugate (PCV) yy Consider a single supplemental dose of PCV13 for children age 6 through 18 years with anatomic or functional asplenia including sickle cell disease and immunocompromising conditions including HIV infection, cochlear implant, or CSF leaks. yy Give a single supplemental dose of PCV13 following a completed PCV7 series for children with certain medical conditions through age 5 years. 11.Pneumococcal polysaccharide (PPSV) yy A single revaccination is recommended 5 years after initial dose for children age 2 years and older with anatomic or functional asplenia or altered immunocompetence. yy Give 1 dose to HCT recipients at 12 and 24 months after HCT. Notes: yy For additional ACIP recommendations refer to www.cdc.gov/vaccines/pubs/ACIP-list.htm. yy Vaccines may be also be indicated during a community outbreak of a disease. Sources: yy CDC. General Recommendations on Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2011:60 [No. RR-02]:1-60. yy American Academy of Pediatrics. Pickering LK, Baker CJ, Kimberlin DW, Long SS, eds. Red Book: 2009 Report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009. 12.Rotavirus (RV1, RV5) yy Contraindicated in children with severe combined immunodeficiency. yy Assess children with altered immunocompetence to determine the risk of prolonged shedding versus the benefit of protection against rotavirus disease. 13.Varicella (VAR) yy Give a 2-dose series 3 months apart to asymptomatic or mildly symptomatic HIVinfected children in CDC class N1 or A1 with age-specific CD4+ T-lymphocyte percentages of 25% or greater. Such children should receive 2 doses of vaccine with a 3-month interval between doses. yy Give 1 dose to HCT recipients 24 months after transplant and if the HCT recipient is presumed to be immunocompetent. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 103 Summary of ACIP Recommendations on Use of Immune Globulin Immune globulin Not immunocompromised HIV-infected Severely immunocompromised1 yy Recommended for patients yy Recommended for exposed to measles symptomatic patients regardless of immunization exposed to measles status regardless of immunization status yy Recommended for patients yy Recommended for patients exposed to hepatitis A exposed to hepatitis A yy Recommended for patients yy Recommended for patients who have not received who have not received hepatitis A vaccination hepatitis A vaccination and and are traveling within are traveling within 2 weeks 2 weeks to hepatitis A to hepatitis A endemic areas endemic areas Immune globulin (IG) yy Recommended for infants and adults exposed to measles with a contraindication to measles vaccine yy Recommended for hepatitis A postexposure in persons less than age 1 year and persons over age 40 years Varicella zoster immune globulin2 (VZIG) yy Recommended for newborns of mothers yy Recommended for who develop chickenpox within 5 days susceptible infants and before through 48 hours after delivery adults after significant exposure to varicella zoster yy Recommended for exposed pre-term infants age 28 or more weeks gestation born to a susceptible mother yy Recommended for exposed preterm infants younger than age 28 weeks gestation or less than 1000 g regardless of mother's susceptibility yy May be used for exposed, susceptible adults, pregnant women, and infants less than 28 days old yy Strongly consider for exposed, susceptible pregnant women yy Recommended for those with serious yy Same as for nonwounds who have received fewer than immunocompromised 3 doses of tetanus toxoid vaccination in their lifetime yy Recommended for susceptible infants and adults after significant exposure to varicella zoster yy Recommended for prophylaxis of infants yy Same as for nonborn to HBsAg+ mothers and susceptible immunocompromised persons with percutaneous, sexual, or mucosal exposure to hepatitis B virus yy Recommended for post-exposure yy Same as for nonprophylaxis of persons not previously immunocompromised vaccinated against rabies yy Same as for nonimmunocompromised Tetanus immune globulin (TIG) Hepatitis B immune globulin (HBIG) Human rabies immune globulin (HRIG) Footnotes: 1. Severely immunocompromised includes primary or acquired immunodeficiency, neoplastic diseases, and immunosuppression. 2. Varicella zoster immune globulin (VZIG) yy The most important use of VZIG is for passive immunization of persons at greater risk for complications (e.g., neonates and susceptible, severely immunocompromised persons) after significant exposure to chickenpox or zoster. yy Varicella-susceptible pregnant women may be at higher risk for serious complications than are adults in general. 104 www.health.state.mn.us/immunize yy Same as for nonimmunocompromised yy Same as for nonimmunocompromised yy VZIG protects pregnant women against severe complications but does not prevent viremia and fetal infection, congenital varicella syndrome, or neonatal varicella. Sources: yy CDC. General Recommendations on Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2011:60 [No. RR-02]:1-60. yy CDC. Prevention of Hepatitis A Through Active or Passive Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2006:55 [No. RR-07]:1-23. Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 July 2011, Minnesota Department of Health If indicated Not indicated -Vaccine is not indicated or no evidence of occupational risk. Recommended www.health.state.mn.us/immunize 105 Recommended Recommended - Vaccine is recommended specifically because of their occupation. Yellow fever13 Varicella12 Typhoid11 If indicated If indicated Pre-exposure rabies9 Tetanus, diphtheria, pertussis:Tdap10/Td If indicated Recommended If indicated If indicated Recommended Tdap Recommended If indicated Recommended Veterinarian, animal handler If indicated (e.g., EMTs, paramedics, police, etc.) Sanitation or sewage worker If indicated Laboratory personnel Meningococcal conjugate8 Measles, mumps, rubella 7 Japanese encephalitis6 Child care, school personnel Give 1 dose of Tdap to all adults regardless of the interval since the last dose of Td If indicated Inactivated poliovirus4 Influenza5 Recommended Health care personnel Hepatitis B3 Hepatitis A2 Anthrax1 Vaccine Essential community service worker Vaccines Indicated by Occupation If indicated - Vaccine is indicated based on specific occupational risk factor. Got Your Shots? Providers Guide - SCREENING & ASSESSING If indicated Recommended College student Vaccines Indicated by Occupation Footnotes: 1. Anthrax yy Give 5 doses and an annual booster dose to laboratory personnel who work: ○○with high concentrations or pure cultures of B. anthracis spores, ○○with environmental samples associated with anthrax investigations, or ○○in spore-contaminated areas or other settings with exposure to aerosolized B. anthracis spores. Note: Consider giving anthrax vaccine to veterinarians and other persons at risk for anthrax if they handle potentially infected animals in research settings or in areas with a high incidence of anthrax cases. 2. Hepatitis A (HepA) yy Give 2 doses to persons who work with hepatitis A-infected primates or with the hepatitis A virus in a research laboratory setting. Note: Studies conducted among U.S. workers exposed to raw sewage do not indicate increased risk for hepatitis A infection. No other populations have been demonstrated to be at increased risk for hepatitis A infection because of occupational exposure. 3. Hepatitis B (HepB) yy Give 3 doses to all persons including health care personnel whose tasks involve exposure to blood or bodily fluids. 4. Inactivated poliovirus (IPV) yy Give a booster dose to health care personnel who have close contact with patients who may be excreting polio virus. yy Give a booster dose to laboratory personnel who are routinely exposed to polio viruses. 5. Influenza yy Give annually to all health care personnel and persons whose occupation involves care or close contact with infants less than age 6 months. Note: Give to all persons regardless of occupation. 6. Japanese encephalitis (JE) yy Give 3 doses to laboratory personnel routinely exposed to Japanese encephalitis. Give a booster dose 12 to 24 months after third dose. 7. Measles, mumps, and rubella (MMR) yy Give 2 doses of MMR to students, health care 106 www.health.state.mn.us/immunize personnel, laboratory personnel, and child care and school personnel unless they have evidence of immunity which includes: ○○documentation of 2 MMR doses, or ○○history of measles, mumps, and/or rubella disease verified by a health care provider, or ○○laboratory evidence of measles, mumps, and/ or rubella immunity. Note: Give at least 1 dose of MMR to all persons who lack evidence of immunity, regardless of occupation. 8. Meningococcal conjugate (MCV) yy Give 1 dose of MCV to previously unvaccinated college freshmen who live in dormitories or whose last dose was 5 or more years ago. yy Give 1 dose to laboratory personnel who are routinely exposed to isolates of N. meningiditis. Give a booster dose every 5 years. 9. Pre-exposure rabies (RAB) yy Give 4 doses to laboratory personnel directly involved with testing or isolating rabies virus. Check serum titers every 6 months and give a booster dose if titers fall below protective levels (i.e., complete neutralization at a 1:5 serum dilution by the RFFIT). yy Give 4 doses to veterinarians and animal handlers. Check serum titers every 2 years and give a booster dose if titers fall below protective levels (i.e., complete neutralization at a 1:5 serum dilution by the RFFIT). 10.Tetanus, diphtheria, pertussis (Tdap/Td) yy Give 1 dose of Tdap to adults age 64 years and younger in place of their next 10-year booster dose of Td. yy Give Tdap to adults having close contact with infants under age 1 year (e.g., parents, child care and health care personnel) regardless of when the last Td was given Note: Tdap is recommended for all adults. 11.Typhoid, oral and inactivated yy Inactivated: Give 1 dose to laboratory personnel routinely exposed to Salmonella typhi. Give a booster dose every 2 years. yy Oral: Give 1 capsule every other day for 4 days to laboratory personnel routinely exposed to Salmonella typhi. Give a booster dose every 5 years. 12.Varicella (VAR) yy Give 2 doses of varicella to health care personnel, laboratory personnel, and child care Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 and school personnel unless they have evidence of immunity, which includes: ○○documentation of 2 doses of varicella vaccine at least 4 weeks apart, or ○○U.S.-born before 1980, or ○○history of varicella disease verified by a health care provider, or ○○history of herpes zoster disease based on health care provider diagnosis, or ○○laboratory evidence of varicella immunity. Note: Give to all persons who lack evidence of immunity, regardless of occupation. 13.Yellow fever (YF) yy Give 1 dose to laboratory personnel routinely exposed to yellow fever virus. Give a booster dose every 10 years. Notes: yy For additional ACIP recommendations refer to www.cdc.gov/vaccines/pubs/ACIP-list.htm. yy Vaccines may also be indicated during a community outbreak of a disease. Sources: yy CDC. General Recommendations on Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2011:60 [No. RR-02]:1-60. yy CDC. Human Rabies Prevention: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2008:57 [No. RR-03]:1-26,28. yy CDC. Immunization of Health-Care Workers: Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the Hospital Infection Control Practices Advisory Committee (HICPAC). MMWR 1997:46 [No. RR-18]:1-42. yy CDC. Prevention of Hepatitis A Through Active or Passive Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2006:55 [No. RR-07]:1-23. yy American College Health Association (ACHA). Recommendations for Institutional Prematriculation Immunizations. Linthicum, MD. ACHA Vaccine Preventable Diseases Committee; January 2009. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 107 July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 108 Healthcare Personnel Vaccination Recommendations1 Vaccine Recommendations in brief Hepatitis B Give 3-dose series (dose #1 now, #2 in 1 month, #3 approximately 5 months after #2). Give IM. Obtain anti-HBs serologic testing 1–2 months after dose #3. Influenza Give 1 dose of influenza vaccine annually. Give inactivated injectable influenza vaccine intramuscularly or live attenuated influenza vaccine (LAIV) intranasally. MMR For healthcare personnel (HCP) born in 1957 or later without serologic evidence of immunity or prior vaccination, give 2 doses of MMR, 4 weeks apart. For HCP born prior to 1957, see below. Give SC. Varicella (chickenpox) For HCP who have no serologic proof of immunity, prior vaccination, or history of varicella disease, give 2 doses of varicella vaccine, 4 weeks apart. Give SC. Tetanus, diphtheria, pertussis Give a one-time dose of Tdap as soon as feasible to all HCP who have not received Tdap previously. Give Td boosters every 10 years thereafter. Give IM. Meningococcal Give 1 dose to microbiologists who are routinely exposed to isolates of N. meningitidis. Give IM or SC. Hepatitis A, typhoid, and polio vaccines are not routinely recommended for HCP who may have on-the-job exposure to fecal material. Hepatitis B Healthcare personnel (HCP) who perform tasks that may involve exposure to blood or body fluids should receive a 3-dose series of hepatitis B vaccine at 0-, 1-, and 6-month intervals. Test for hepatitis B surface antibody (anti-HBs) to document immunity 1–2 months after dose #3. t If anti-HBs is at least 10 mIU/mL (positive), the patient is immune. No further serologic testing or vaccination is recommended. t If anti-HBs is less than 10 mIU/mL (negative), the patient is unprotected from hepatitis B virus (HBV) infection; revaccinate with a 3-dose series. Retest anti-HBs 1–2 months after dose #3. – If anti-HBs is positive, the patient is immune. No further testing or vaccination is recommended. – If anti-HBs is negative after 6 doses of vaccine, patient is a non-responder. For non-responders: HCP who are non-responders should be considered susceptible to HBV and should be counseled regarding precautions to prevent HBV infection and the need to obtain HBIG prophylaxis for any known or probable parenteral exposure to hepatitis B surface antigen (HBsAg)-positive blood.1 It is also possible that non-responders are persons who are HBsAg positive. Testing should be considered. HCP found to be HBsAg positive should be counseled and medically evaluated. Note: Anti-HBs testing is not recommended routinely for previously vaccinated HCP who were not tested 1–2 months after their original vaccine series. These HCP should be tested for anti-HBs when they have an exposure to blood or body fluids. If found to be anti-HBs negative, the HCP should be treated as if susceptible.2 Influenza All HCP, including physicians, nurses, paramedics, emergency medical technicians, employees of nursing homes and chronic care facilities, students in these professions, and volunteers, should receive annual vaccination against influenza. Live attenuated influenza vaccine (LAIV) may only be given to non-pregnant healthy HCP age 49 years and younger. Inactivated injectable influenza vaccine (TIV) is preferred over LAIV for HCP who are in close contact with severely immunosuppressed persons (e.g., stem cell transplant patients) when patients require protective isolation. Measles, Mumps, Rubella (MMR) HCP who work in medical facilities should be immune to measles, mumps, and rubella. tHCP born in 1957 or later can be considered immune to measles, mumps, or rubella only if they have documentation of (a) laboratory confirmation of disease or immunity or (b) appropriate vaccination against measles, mumps, and rubella (i.e., 2 doses of live measles and mumps vaccines given on or after the first birthday and separated by 28 days or more, and at least 1 dose /iV V>ÊVÌiÌÊÀiÛiÜi`ÊLÞÊÌ iÊ iÌiÀÃÊvÀÊÃi>ÃiÊ ÌÀÊ>`Ê*ÀiÛḭ of live rubella vaccine). HCP with 2 documented doses of MMR are not recommended to be serologically tested for immunity; but if they are tested and results are negative or equivocal for measles, mumps, and/or rubella, these HCP should be considered to have presumptive evidence of immunity to measles, mumps, and/or rubella and are not in need of additional MMR doses. tAlthough birth before 1957 generally is considered acceptable evidence of measles, mumps, and rubella immunity, healthcare facilities should consider recommending 2 doses of MMR vaccine routinely to unvaccinated HCP born before 1957 who do not have laboratory evidence of disease or immunity to measles and/or mumps, and should consider one dose of MMR for HCP with no laboratory evidence of disease or immunity to rubella. For these same HCP who do not have evidence of immunity, healthcare facilities should recommend 2 doses of MMR vaccine during an outbreak of measles or mumps and 1 dose during an outbreak of rubella. Varicella It is recommended that all HCP be immune to varicella. Evidence of immunity in HCP includes documentation of 2 doses of varicella vaccine given at least 28 days apart, history of varicella or herpes zoster based on physician diagnosis, laboratory evidence of immunity, or laboratory confirmation of disease. Tetanus/Diphtheria/Pertussis (Td/Tdap) All HCPs who have not or are unsure if they have previously received a dose of Tdap should receive a one-time dose of Tdap as soon as feasible, without regard to the interval since the previous dose of Td. Then, they should receive Td boosters every 10 years thereafter. Meningococcal Vaccination is recommended for microbiologists who are routinely exposed to isolates of N. meningitidis. Use of MCV4 is preferred for persons age 55 years or younger; give IM. Use MPSV4 only if there is a permanent contraindication or precaution to MCV4. Use of MPSV4 (not MCV4) is recommended for HCP older than age 55; give SC. References 1. CDC. Immunization of Health-Care Personnel: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR, 2011; 60(RR-7). 2. See Table 3 in “Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV and Recommendations for Postexposure Prophylaxis,” MMWR, 2001; 50(RR-11). For additional specific ACIP recommendations, refer to the official ACIP statements published in MMWR. To obtain copies, visit CDC’s website at www.cdc.gov/vaccines/ pubs/ACIP-list.htm; or visit the Immunization Action Coalition (IAC) website at www. immunize.org/acip. Adapted from the Michigan Department of Community Health ÜÜܰÕâi°À}ÉV>Ì}°`É«Óä£Ç°«`vÊÊUÊÊÌiÊ*Óä£ÇÊÇÉ£Ó® Õâ>ÌÊVÌÊ >ÌÊÊUÊÊ£xÇÎÊ-iLÞÊÛi°ÊÊUÊÊ-̰Ê*>Õ]Ê Êxx£ä{ÊÊUÊÊÈx£®ÊÈ{ÇääÊÊUÊÊÜÜܰÕâi°À}ÊÊUÊÊÜÜܰÛ>VVivÀ>̰À} July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 109 110 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 111 gripa MMR rubeola Human papillomavirus Influenza MMR Measles veliki kašalj dje ja paraliza upala plu a Rotavirus male boginje Pertussis Poliomyelitis Pneumococcal conjugate Rotavirus Rubella tetanus tuberkuloza ospice Tetanus Tuberculosis Varicella (chickenpox) Immunization Action Coalition veliki boginje Smallpox Shingles (Herpes zoster) zauŠnjaci zauške Mumps y ycka y (651) 647-9009 ветряная оспа (вітрянка) şi varicelă (varicelă) y туберкулеѕ столбняк оспа опоясывающий лишай tuberculozei tetanosului variola, variolei Herpes zoster (zona zoster) краснуха rubeola, rubeolei, pojar German St. Paul, MN 55104 ospy wietrznej (ospa wietrzna) gruzlica tężcowi ospa półpasiec r ротавірусной y пневмококковоя конъюгированной пoлиомиелит коклюша свинка, ларотит менингококковая сопряженных коpЬ грипп вирус папилломы человека гепатит B rotavirus pneumococic conjugat skoniugowanej szczepionki pneumokokowej rotavirusy poliomielita tusei convulsive polio krztuścowi oreionul, oreion conjugate meningococice swinka pojarul meningokokom sprzężenia gripa papilomavirus uman hepatita B гепатит А гемофільной инфекции типа B hepatita A дифтерия Haemophilus influenzae tip b boala АКДС Russian difteriei Di-Te-Per Romanian odra grypa 1573 Selby Avenue varicella (vodene kozice) tuberkuloza tetanusa veliki boginje šindra rubeola rotavirusa pneumokoka konjugirano dječje paralize kašalj hripavac meningokoknog konjugirati Meningococcal conjugate ospice gripe utica B, hepatitisa B papilomavirusi čovjeka utica B, Hepatitis B Ljudski papiloma virus Hepatitis B wirusowemu zapaleniu wątroby typu A wirusowemu zapaleniu wątroby typu B wirus brodawczaka ludzkiego utica A, hepatitisa A utica A, Hepatitis A Hepatitis A Haemophilus influenzae typu b Haemophilus influenzae tipa b Haemophilus influenzae type b Hemofili na influenca tipa B difterija Diphtheria Detepe Polish przeciwko błonicy Detepe DTP Croatian difterije Bosnian English Eastern European Languages y (Page 1 of 2) y вітряної віспи (вітрянка) правця оперізуючий герпес (оперізуючий лишай) ротавірусної пневмококковой конъюгированной поліомієліту кашлюку кір менінгококова сполучених грипу вірус папіломи людини гепатиту В гепатиту S гемофільної інфекції типу B захворювань дифтерії Ukrainian [email protected] ovčím kiahňam (ovčie kiahne) Варицелла (цхицкен богиње) www.immunize.org tuberkulóza tetanus kiahne pásového oparu (pásový opar) rubeola Ροтавирус konjugovaná pneumokoková detská obrna čierny kašeľ parotitis meningokokove j konjugovanou morbilli, osýpky chrípka ľudský papillomavírus hepatitída B hepatitída A Haemophilus influenzae typ b ochorenia záškrt DiTePe Slovak Tuberkuloza тетануса veliki boginje херпес зостер (појасни херпес) Ρубеοла рота-вируса Пнеумоцоццал коњунговане дечје парализе великог кашља Эаушκе менингококне коњуговано Μале бοгиње ΜMR грип људски папилома вирус хепатитиса Б хепатитиса A Хаемопхилус инфлуензае тип Б болести дифтерије Detepe Serbian Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages 112 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Haemophilus influenzae b hepatitis A Haemophilus influenzae type b Hepatitis A y Haemophilus influenzae type b Haemophilus influenzae de type b BMR mazelen meningokokken conjugaat bof MMR Measles Meningococcal conjugate Mumps pneumokokken conjugaat rotavirus rode hond gordelroos (herpes zoster) pokken tetanus tering varicella (waterpokken) Pneumococcal conjugate Rotavirus Rubella Shingles (Herpes zoster) Smallpox Tetanus Tuberculosis Varicella (chickenpox) Immunization Action Coalition poliomyelitis Poliomyelitis (Whooping cough) kinkhoest influenza (griep) Influenza (“flu”) Pertussis grippe humaan papillovirus Human papillomavirus y varicella tubercolosi tetano y (651) 647-9009 vannkopper (vannkopper) tuberkulose stivkrampe kopper helvetesild (herpes zoster) fuoco di Sant’Antonion (l’herpes zoster) vaioloso røde hunder rotavirus pneumokokk komjugatvaksine poliomyelitt kikhoste kusma meningokokksykdom konjugert meslinger influensa humant papillomavirus hepatitt B hepatitt A Haemophilus influenzae tipe b difteri Norwegian rosolia rotavirus pneumococcico coniugato poliomielite (tosse asinina) pertosse parotite coniugato meningococcico morbillo MPR l’nfluenzae il papillovirus umano epatite B epatite A Haemophilus influenzae b difterite Italian St. Paul, MN 55104 varizellen (windpocken) tuberkulose wundstarrkrampf pocken 1573 Selby Avenue varicelle tuberculose tétanos variole gürtelrose (herpes zoster) röteln - rubéole - rubéola zona (l’herpès zoster) rotavirus pneumokokken konjugat kinderlähmung keuchhusten ziegenpeter meningokokken konjugatimpfstoff masern MMR influenza (grippe) humanen papillovirus hepatitis B rotavirus antipneumococcique conjugué poliomyélite coqueluche oreillons conjugué contre le méningocoque rougeole ROR papillovirus humaines hepatitis B Hepatitis B hepatite B hepatite A hepatitis A diphtherie diphtérie difterie Diphtheria DT Coq, DTC DKTP German DTP French Dutch English Western European Languages y y varicela www.immunize.org varicella (catapora) y vattkopper tuberkulos stelkramp smittkopper bältros (herpes zoste) röda hund rotavirus konjugerat pneumokock poliomyelitis kikhosta påssjuka meningokockinfektion konjugatet mässling MPR influensa mänskliga papillovirus hepatit B hepatit A Haemophilus influenzae typ b difteri trippel Swedish (Page 2 of 2) [email protected] tuberculínica tétanos, tetánica, tétano tétano, tetânica tuberculose viruela zona de matojos (herpes) rubéola, sarampión aleman rotavirus polio, poliomielitis antineumocócica conjugada (tos ferina) coqueluche paperas, parotiditis sarampión, sarampión comun meningococo conjugada SRP influenza (gripe) Virus del papiloma humano hepatitis B hepatitis A Hemófilo tipo b, Haemophilus influenzae tipo b Difteria Spanish varíola zona (herpes zoster) rubéola (sarampo alamão) rotavírus poliomielite, paralisia Infantil pneumocócica conjugada coqueluche caçhumba meningocóccica conjugada sarampo SPR influenza (gripe) virus do papiloma humano hepatite B hepatite A doenca Haemophilus influenzae tipo b difteria Tríplice Portuguese Quick Chart of Vaccine-Preventable Disease Terms in Multiple Languages The CDC is maintaning the following documents in the Pink Book as table 1 and 2 of Appendix B: Table 1: Disease, Vaccine and Related Terms (previously Vaccines and Biologics Used in U.S. and Foreign Markets) Table 2: Trade Names (previously Translation of Vaccine-Related Terms Into English) Also available on the web at www.cdc.gov/vaccines/pubs/pinkbook/index.html Foreign Language Terms Aids to translating foreign immunization records. Table 1: Disease, Vaccine, and Related Terms. This table lists terms for vaccinepreventable diseases and vaccines, and other terms that might be found on an immunization record, by language. Table 2: Trade Names. This table lists the names of specific vaccines that are used, or have been used, internationally, along with the manufacturer and country or region where the vaccine is produced or used, when known. These tables have been adapted from (among other sources) lists developed by the Minnesota Department of Health Immunization Program (now maintained by the Immunization Action Coalition) and Washington State Department of Health. See also: http://www.immunize.org/izpractices/p5120.pdf http://www.immunize.org/izpractices/p5121.pdf These lists are not comprehensive. We have checked sources, but we cannot claim complete accuracy. Centers for Disease Control and Prevention. Epidemiology and Prevention of VaccinePreventable Diseases (The Pink Book). Atkinson W, Wolfe S, Hamborsky J, eds. 12th ed., second printing. Washington DC: Public Health Foundation, 2012. July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 113 Foreign Vaccines Table 1: Disease, Vaccine, and Related Terms Difteria Fruthi Pertusisi Tetanozi Albanian Arabic Alhasiba As’al Athab Difteria El Safra Has ‘ba Shel’el Bosnian Beseže Detepe Difterija Djeþja paraliza Gripa Male boginje Ospice Rubeola Upala pluüa Veliki boginje Veliki kašalj Zauške Žutica Croatian Beseže Detepe Difterija Djeþja paraliza Gripa Hri pavac Kašalj hripavac Upala pluüa Veliki boginje Vodene kozice Zapaljenje ZauŠnjaci Žutica Davivy Kasel Difterie Hepatitida 114 Czech www.health.state.mn.us/immunize Diphtheria Measles Pertussis Tetanus Rubella Pertussis Mumps Diphtheria Hepatitis Measles Polio BCG DPT Diphtheria Polio Influenza Rubella Measles Rubella Pneumonia Smallpox Pertussis Mumps Hepatitis BCG DTP Diphtheria Polio Influenza Pertussis Pertussis Pneumonia Smallpox Varicella Hepatitis Mumps Hepatitis Pertussis Diphtheria Hepatitis Parotitida Pertuse Poliomyelitis Plané Nestovice Spalnicky Subinuira Zardenky Zaškrt Zlutá Zimnice Mumps Pertussis Polio Chickenpox Measles Influenza Rubella Diphtheria Yellow Fever Danish Bornelammelse Difteritis Faaresyge (Fåresyge) Kighoste Leverbetaendelse Meslinger MFR Rode Hunde Stivkrampe Dutch BMR Bof Difterie DKTP Gelekoorts Gordelroos Griep Kinderverlamming Kinkhoest Longontsteking Mazelen Pokken Rode hond Stijfkramp Tering Waterpekkea Polio Diphtheria Mumps Pertussis Hepatitis Measles MMR Rubella Tetanus MMR Mumps Diphtheria DTP + IPV Yellow Fever Varicella Influenza Polio Pertussis Pneumonia Measles Smallpox Rubella Tetanus Tuberculosis Chickenpox Ethiopian (Oromiffaa) Cufaa Difteeriyaa Gifira Gifira farangli Laamsheesaa Qakkee Shimbiraa Hinkuyska Got Your Shots? Providers Guide - SCREENING & ASSESSING Tetanus Diphtheria Measles Rubella Polio Pertussis Hepatitis Finnish Pertussis Minnesota Department of Health, July 2011 Jaykkakouristus Kurkkumata Lapsihalvaus Sikotauti Tuhkarokko Vihurirokko Tetanus Diphtheria Polio Mumps Measles Rubella French Coqueluche Diphtérie DTC, DT Coq DTCP Fievre jaune Grippe l’Haemophilus b Oreillons Poliomyélite ROR Rougeole Rubéole Tétanos Tuberculose Variole Diphtherie Pertussis Diphtheria DTP DTP +Polio Yellow Fever Influenza Hib Mumps Polio MMR Measles Rubella Tetanus Tuberculosis Smallpox German Diphtheria Tick-borne encephalitis Yellow Fever Influenza Pertussis Polio Measles Smallpox Rubella Tetanus Tuberculosis Tetanus Mumps FSME Gelbfieber Grippe Keuchhusten Kinderlähmung Masern Pocken Röteln Starrkramph Tuberkulose Wundstarrkrampf Zei Genpeter Greek ǻȚQșJȡȓIJȚįĮ, ȉȑIJĮȞȠȢ țĮȚ ȀȠțțȪIJȘȢ ȅ ǹȚȝȩQȚȜȠȢ IJȘȢ ȖȡȓʌʌȘȢ IJȪʌȠȣ Ǻ ȂȘȞȚȖȖȠțȠțțȚțȒ ǹıșȑȞJĮ ȠȝȐįĮȢ C ǿȜĮȡȐ - ȂĮȖȠȣȜȐįJȢ – ǼȡȣșȡȐ ȆȠȜȚȠȝȣJȜȓIJȚįĮ ȉȑIJĮȞȠȢ țĮȚ ǻȚQșJȡȓIJȚįĮ DTP Hib Meningococcal C MMR Polio Td Haitian Creole Difteri Epatit Flou Koklich LawoujEl, LaroujEl July 2011, Minnesota Department of Health Diphtheria Hepatitis Influenza Pertussis Measles Malmouton Polyo RibeyEl Saranpyon TetanEs Mumps Polio Rubella Varicella Tetanus Hmong Hawb pob Kabmob siab hom B Kub cer Qhua Maj Qhua Pias Qog Tuag tes tuag taw Ua npuag Indonesian Batuk rejan Beguk Biring Peluh Campak Difteri Penyakit lumpuh Radang hati Italian Antipolio inattivato Difterite Emofilo b Epatite Febbre Giallo Morbillo MPR (morbillo, parotite, rosolia) Parotite Pertosse Poliomielite Polmonite Rosolia Tetano Tosse Asinina Tubercolosi Vaioloso Japanese A ဳ⢄Ἳ B ဳ⢄Ἳ Fushin (㘑∐ Hashika (㤗∐QTߪߒ߆ Hashofu (⎕்㘑) Hyakaseki (⊖ᣣຕ) Jifuteria (ࠫࡈ࠹ࠕ) Otafukukuaze (ᵹⴕᕈ⡊ਅ⣼Ἳ or߅ߚ߰ߊ߆ߗ) Got Your Shots? Providers Guide - SCREENING & ASSESSING Pertussis Hepatitis B Diphtheria Rubella Measles Mumps Polio Tetanus Pertussis Mumps Rubella Measles Diphtheria Polio Hepatitis IPV Diphtheria Hib Hepatitis Yellow Fever Measles MMR Mumps Pertussis Polio Pneumonia Rubella Tetanus Pertussis Tuberculosis Smallpox Hepatitis A Hepatitis B Rubella Measles Tetanus Pertussis Diphtheria Mumps www.health.state.mn.us/immunize 115 Sh naimahi (ࡐࠝ) ਃ⒳ᷙว ᳓∧or ߺߕ߷߁ߘ߁ ⢖Ἳ⩶ ࠗࡦࡈ࡞ࠛࡦࠩ⩶ ᣣᧄ⣖Ἳ ࠗࡦࡈ࡞ࠛࡦࠩ ࠷ࡌ࡞ࠢࡦ ㅊടធ⒳ Malay Batok rejan Penyaakit bengok Sakit champak Sakit rengkong Norwegian Difteri Kikhoste Kopper Kusma Leverbetennelse Meslinger Poliomyelitt RUde hunder Stivkrampe Vannkopper Polish Báonicy, Báonica, Báonnica Dyfteria Gruzlica Grypa Koklusz Krztuscowi, Krztusiec Odra Ospa Ospa Wietrzna Paraliz dzieciecy Pojar German Pojarul, Pojarului Przypominajace Rozyczka Swinka Tezec, TĊžcowi Zapalenie pluc Zapalenie watroby Zólta Goraczka Portugese Cachumba (papeira) Coqueluche Difteria 116 www.health.state.mn.us/immunize Polio DTaP Varicella Pneumococcal Hib Japanese Encephalitis Influenza PPD Booster Pertussis Mumps Measles Diphtheria Diphtheria Pertussis Smallpox Mumps Hepatitis Measles Polio Rubella Tetanus Varicella Diphtheria Diphtheria Tuberculosis Influenza Pertussis Pertussis Measles Smallpox Chickenpox Polio Rubella Measles Booster Rubella Mumps Tetanus Pneumonia Hepatitis Yellow Fever Mumps Pertussis Diphtheria Febre Amarela Gripe Hepatite Paralisia infantil Parotidite epidémica Poliomielite Rúbéola Sarampo Tetânica, Tétano Triplice VAHB VAP Varicela VAS VASPR VAT Yellow Fever Influenza Hepatitis Polio Mumps Polio Rubella Measles Tetanus DTP Hepatitis B Vaccine Polio Vaccine Chickenpox Measles Vaccine MMR Tetanus Vaccine Romanian AR Difteria (Difteriei) Di Te Di-Te-Per Febra Galbena Gripa Hepatita Holera Oreion, Oreionului Pneumoniei Poliomielitic Rubeolei, Rubeola Rujeola, Rujeolei Tetanos,Tetanosul, Tetanosului Tuse convulsiva, Tusei convulsive Varicelă, Varicelei Variola, Variolei Russian ȻɰU ȺɄȾɋ Ⱦɢɮɬɟɪɢɬ, Ⱦɢɮɬɟɪɢɹ Ƚɟɦɨɢɮɥɸɫ ɢɧɮɥɸɡɧɰɵ ɬɢɩɚ Ȼ Ƚɟɩɚɬɢɬ Ƚɪɢɩɩ Ʉɨɪɶ ɋɜɢɧɤɚ, ɉɚɪɨɬɢɬ Ʉɨɥɸɲ ȼɨɫɩɚɥɟ ɥɺɝɤɢɯ ɉɧɟɜɦɨɧɢɹ ɉɨɥɢɨɦɢɟɥɢɬ Ʉɪɚɫɧɭɯɚ Ɉɫɩɚ ɋɬɨɥɛɧɹɤ, ɋɬɨɥɛɧɹɤɚ Got Your Shots? Providers Guide - SCREENING & ASSESSING Measles Diphtheria DT DTP Yellow Fever Influenza Hepatitis Cholera Mumps Pneumonia Polio Rubella Measles Tetanus Pertussis Varicella Smallpox BCG DTP Diphtheria Hib Hepatitis Influenza Measles Mumps Pertussis Pneumonia Polio Rubella Smallpox Tetanus Minnesota Department of Health, July 2011 Ɍɭɛɟɪɤɭɥɟɡ ȼɟɬɪɹɧɤɚ Ɇɚɧɬɭ ȼɚɤɰɢɧɚ ȼɚɤɰɢɧɚɰɢɹ Ɋɟɜɚɤɰɢɧɚɰɢɹ Mami Misela Rupela Samoan Serbian Beseže Detepe Difterija Djeþja paraliza Gripa Hri pavac Male boginje Pljuskavice, Kozice Upala pluüa Veliki boginje Veliki kašalj Zapaljenje ZauŠnjaci Žutica Slovak Chripka Cierny kasel Diftéria DiTePe Hepatitida Krzamak Osypky Parotitis Polyomyelitida Priusnica Ruzienka Zápalplüc Záskrt Spanish Cólera Coqueluche Difteria Doble Antigen Doble Viral Duple Gripe Hemófilo tipo b Numonía July 2011, Minnesota Department of Health Tuberculosis Varicella Mantoux (TB Test) Vaccine Series Booster Mumps Measles Rubella BCG DTP Diphtheria Polio Influenza Pertussis Rubella Varicella Pneumonia Smallpox Pertussis Hepatitis Mumps Hepatitis Influenza Pertussis Diphtheria DTP Hepatitis Measles Measles Mumps Polio Mumps Rubella Pneumonia Diphtheria Cholera Pertussis Diphtheria Td (Mexico) Measles-Rubella (Mexico) DT (Cuba) Influenza Hib Pneumonia Paperas, Parotiditis Poliomielitis Pulmonía Rubéola Sarampión, Sarampión Comun Sarampión Aleman SPR Tetánica, Tétano Tos Ferina Varicela Viruela Somali Bus-buska Cagaarshowga Cuno xanuun Dabayl Duf Furuq Gowracato Gurra dhaabsis Hablobaas Haemophilus nooca b Infilowense Jadeeco Jadeeco been, Jadeeco jarmalka Joonis Kix Qaamow-Qashiir Qaaxo-Tiibi Qanja Barar Sambabaha Tallaakla Qaaxada Taytano Wareento Xiiqdheer Swedish Got Your Shots? Providers Guide - SCREENING & ASSESSING Varicella Hepatitis Diphtheria Polio Polio Smallpox Diphtheria Mumps Varicella Hib Influenza Measles Rubella Hepatitis Pertussis Mumps Tuberculosis Mumps Pneumonia BCG Tetanus Pneumonia Pertussis Difteri Duplex Gula Febern Kikhosta Kolera Mässling, Masslingormerly Păssjura Polio RĘda Hund Smittkoppor Stelkramp Trippel Beke Mumps Polio Pneumonia Rubella Measles Rubella MMR Tetanus Pertussis Varicella Smallpox Tagalog Diphtheria DT Yellow Fever Pertussis Cholera Measles Mumps Polio Rubella Smallpox Tetanus DTP Mumps www.health.state.mn.us/immunize 117 Dipterya Pertusis Polyo Tetano Tigdas Diphtheria Pertussis Polio Tetanus Measles Turkish Bomaca Çocuk Felci DBT Difteri Erken Yaz-Beyin IltihabȚ’na Grip KKK Kabakulak KȚzamȚk KȚmamȚkçȚk Meningekoklar Kuduz Pnömokoklar Su Çiçei Tetanos Ukranian Ʉɿɪ ɉɨɥɿɨ ɋɬɨɜɧɹɤ Vietnamese Bach Hâu Bai liet Ban Ĉo Dai Ho G% Quai Bi S%i Uon Ván So’i Sot T/ Li/t Thuong h%n Uon ván Vi/m gan si/u vi B (VGSV B) VNNB 118 www.health.state.mn.us/immunize Pertussis Polio DPT Diphtheria Tick-borne encephalitis Influenza MMR Mumps Measles Rubella Meningococcal Rabies Pneumococcal Varicella Tetanus Measles Polio Tetanus Diphtheria Polio Rubella Rabies Pertussis Mumps Tetanus Measles Polio Typhoid Tetanus Hepatitis B Japanese encephalitis April 2009 Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Foreign Language Terms Table 2: Product Names Trade Name Antigen(s) Manufacturer, Country A.D.T. Diphtheria, tetanus, pertussis, polio, Hib, hepatitis B Diphtheria, tetanus (adsorbed) A.K.D.S. Diphtheria, tetanus, pertussis UK ACVax GSK, UK Acelluvax Meningococcal (polysaccharide A & C) Meningococcal (polysaccharide A, C, Y, W135) Pertussis (acellular) ACTAcel Diphtheria, tetanus, pertussis, Hib Sanofi Pasteur, Argentina Adifteper Diphtheria, tetanus, pertussis Ism, Italy Adinvira A+B Influenza (whole virus) Imuna Adiugrip Influenza Sanofi Pasteur Admun Influenza (whole virus) Duncan Admune GP Influenza (whole virus) Duncan Agrippal Influenza Novartis AH Hepatitis B Aimmugen Hepatitis A (inactivated) Aldiana Diphtheria (adsorbed) (Romania) Chemo-Sero-Therapeutic Resh Inst. Japan Sevac, Czech Republic Alditeana Sevac, Czech Republic Almevax Diphtheria, tetanus (adsorbed) Diphtheria, tetanus (adsorbed), pertussis Rubella Alorbat Influenza (whole virus) Asta Pharma Alteana Sevac Tetanus Institute of Sera and Vaccines AM-BC Meningococcal B & C Cuba Amaril Yellow Fever Sanofi Pasteur, France AmBirix Hepatitis A, Hepatitis B GSK, Europe AMC Hib (polysaccharide) Cuba Anadifterall Diphtheria (adsorbed) Chiron, Italy Anatetall Tetanus (adsorbed) Chiron, Italy Anatoxal Di Te Diphtheria, tetanus Berna Biotech, Europe Anatoxal Di Te per Diphtheria, tetanus, pertussis Berna Biotech, Europe AP Polio (Romania) AS Measles Cuba Arilvax Yellow fever MEDI, UK ATPA Tetanus toxoid (Romania) AVAC-1, AVA Anthrax (for U.S. military use) AVAXIM Hepatitis A Aventis Pasteur, France B-Hepavac II Hepatitis B Merck, Singapore 6 in 1 ACWYVax Alditerpera July 2011, Minnesota Department of Health GSK, Ireland Commonwealth, Australia GSK, UK Chiron, Italy Sevac, Czech Republic Evans Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 119 Trade Name Antigen(s) Manufacturer, Country Begrivac Influenza (split virus) Novartis Betagen Biaflu Zonale Biken-HB Bilive Biviraten Berna Buccopol Berna BVAC Hepatitis B Influenza (whole virus) Hepatitis B Hepatitis A/Hepatitis B (recombinant) Hepatitis B (recombinant, adsorbed, yeast derived) Measles, mumps (live) Polio (oral) Botulinum antitoxin B-Vaxin Hepatitis B C.D.T. CEF Cacar Campak Kerig Celluvax Chiromas Cinquerix Cocquelucheau Cuadruple Diphtheria, tetanus (pediatric, adsorbed) Measles (Schwarz strain) Smallpox Measles Pertussis (acellular) Influenza (same as Fluad) Diphtheria, tetanus, pertussis, Hib, polio Pertussis (adsorbed) Diphtheria, tetanus, pertussis, Hib D-Immun Diphtheria Sanofi Pasteur Farmabiagini, Italy Biken, Japan Sinovac, China Chemo-Sero-Therapeutic Resh Inst., Japan Berna Biotech, Switzerland Berna Biotech, Europe (for U.S. military use) Laboratorios Pablo Cassara, Argentina Commonwealth, Australia Chiron, Italy Indonesia Pasteur Institute, Indonesia Chiron, Italy Novartis, Spain GSK, Europe Sanoti Pasteur, France Mexico Osterreichisches Institut, Austria Bimmugen D.S.D.P.T. D.T. Bis Rudivax Di Anatoxal Di Te Per Pol Impfstoff Diphtheria, tetanus, pertussis (adsorbed) Diphtheria, tetanus, rubella Diphtheria Sanofi Pasteur, France Berna Biotech, Europe Diphtheria, tetanus, pertussis, polio Berna Biotech, Switzerland Di-Te-Pol SSI Diphtheria, tetanus, polio Dif-Tet-All Diftavax Ditanrix DiTe Anatoxal Ditoxim Double Anigen B.I. DT Adulte DT Bis DT Coq DT Polio Diphtheria, tetanus Diphtheria, tetanus Diphtheria, tetanus Diphtheria, tetanus (adsorbed) Diphtheria, tetanus (adsorbed) Diphtheria, tetanus Diphtheria, tetanus (adult) Diphtheria, tetanus (booster) Diphtheria, tetanus, pertussis Diphtheria, tetanus, polio Diphtheria, tetanus Salmonella typhi, Paratyphi A & B Diphtheria, tetanus (pediatric) Diphtheria, tetanus (pediatric) Diphtheria, tetanus (adsorbed) Diphtheria, tetanus, polio Diphtheria, tetanus Diphtheria, tetanus DTwP-Hib-HepB Measles, rubella (Schwarz & RA 27/3) DT TAB DT Vax DT Wellcovax Dual Antigen Sii Dultavax Dupla Duplex Easyfive Ecolarix 120 www.health.state.mn.us/immunize Dong Shit Pharm, Korea Statens Seruminstitut, Denmark Chiron, Italy Sanofi Pasteur GSK, Europe Berna Biotech, Switzerland Dong Shin Pharm, Korea Bengal Immunity Co., India Sanofi Pasteur, France Sanofi Pasteur, France Sanofi Pasteur, France Sanofi Pasteur, France Sanofi Pasteur, France Sanofi Pasteur, France Chiron, UK Serum Institute of India (Sii) Aventis Pasteur, France Instituto Butantan, Brazil Sweden India GSK, Europe Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Trade Name Antigen(s) Manufacturer, Country VEB, Sachsesches Serumwerk Dresden Chiron, Europe Centro de Ingenieria Genetica Y Biotecnologia, Cuba Isi CSL GSK, Europe Berna Biotech, Switzerland GSK, Mexico GSK, Belgium Elvarix Influenza (split virus) Encepur Tick-borne encephalitis Enivac-HB Hepatitis B (recombinant DNA) Enterovaccino Enzira Eolarix Epaxal Berna Ervax Ervevax RA 27/3 Euvax-B Typhoid (IM) Influenza Measles, rubella (Schwartz & RA 27/3) Hepatitis A – virosomal vaccine Rubella (live) Rubella (live) (Hexavalent) Diphtheria, tetanus, pertussis, polio, Hib, hepatitis B Hepatitis B (recombinant DNA) Fendrix Hepatitis B (dialysis formulation) GSK, Europe Fluad Influenza (adults >65) Novartis, Europe, Asia, NZ Flubron Influenza (whole virus) Pfizer Flugen Influenza UK Fluvax Influenza CSL, Australia Fluvirine Influenza CellTech Pharma SA FOH-M Polio (inactivated) Russia FrocuoOke Polio (inactivated) Russia FSME-IMMUNE Tick-borne encephalitis Baxter, Austria FSPD Measles Russia Funed-CEME Diphtheria, tetanus, pertussis Belo Horizonte, Brazil Gen H-B-Vax GenHevac B Pasteur Gene Vac-B Hepatitis B Merck-Behringwerke Hepatitis B Sanofi Pasteur Hepatitis B Serum Institute of India (Sii) Gripax Influenza (whole virus) Hebrew University Gripe Influenza (whole virus) Spain Gripguard Influenza (same as Fluad) Novartis, France Gripovax Influenza (whole virus) GSK Gunevax Rubella Chiron, Italy H-Adiftal Diphtheria Ism, Italy H-Adiftetal Diphtheria, tetanus Ism, Italy H-Atetal HarPaBreHnr B CtauOHAP HAVPur Tetanus Ism, Italy Rubella Russia Hepatitis A Chiron, Germany HB Vax Pro Hepatitis B SP HBY Hepatitis B (recombinant) KGC, Japan HDCV Human Diploid Cell Rabies Vaccine Heberbiovac HB Hepatitis B Heberbiotec, Cuba Hepabest Hepatitis A Sanofi Pasteur, Mexico Esavalenti July 2011, Minnesota Department of Health Italy LG Chemical, South Korea Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 121 Trade Name Antigen(s) Manufacturer, Country Hepacare Hepatitis B (recombinant) Chiron, Europe Hepaccine-B Hepatitis B (plasma derived) Chiel Jedang, South Korea Hepagene Hepatitis B Chiron, Europe Hepativax Hepatitis B Sanofi Pasteur, Mexico Hepatyrix Hepatitis A, typhoid Hepavax-B Hepatitis B (plasma derived) Hepavax-Gene Hepatitis B (recombinant DNA) Hepcare Heprecomb Hevac B Hiberix HIBest Hepatitis B Hepatitis B (yeast derived) Hepatitis B (plasma derived) Diphtheria, tetanus, pertussis, polio, hepatitis B, Hib Hib conjugate Hib Hinkuys karokoe Pertussis (adsorbed) HIS Influenza IBV Polio (inactivated) Immravax Immugrip Immunil Imovax Parotiditis Imovax Polio Imovax Sarampion Imovas D.T. Imovas Gripe Imovax D.P.T. Imovax R.O.R. Imovax Rubeola Imovax Mumps Imovax Oreillons Imovax Rage Imovax Tetano Infanrix Quinta Infanrix Tetra Measles, mumps, rubella Influenza Pneumococcal (polysaccharide) Mumps Polio Measles Diphtheria, tetanus (adult) Influenza Diphtheria, tetanus, pertussis Measles, rubella, mumps (live) Measles Mumps Mumps Rabies Tetanus Diphtheria, tetanus, pertussis, polio, Hib, hepatitis B Diphtheria, tetanus, pertussis, hepatitis B, polio Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio GSK Korea Green Cross, South Korea Korea Green Cross, South Korea Chiron, Europe Berna Biotech, Switzerland Sanofi Pasteur, France Sanofi Pasteur, Europe or Mexico GSK Sanofi Pasteur Natl. Public Health Institute, Finland Serbian Institute, Yugoslavia Statens Seruminstitut, Denmark Sanofi Pasteur, Europe Pierre Fabre Médicament Sidus Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur Mexico Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Sanofi Pasteur, Europe Inflexal Influenza Influmix Influpozzi Zonale Influenza (whole virus) Influenza (whole virus) Influsplit SSW Influenza (split virus) Influvac Influvirus Influenza Influenza Hexavac (Hexavax) Infanrix Hexa Infanrix Penta 122 www.health.state.mn.us/immunize GSK, France GSK, Europe GSK, Europe GSK, Europe Swiss Serum and Vaccine Institute Schiapparelli Ivp VEB Sachsecsches Serumwerk Dresden Solvay-Pharma Ism, Italy Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Trade Name Antigen(s) Manufacturer, Country Invirin Ipad TP IPV-Virelon Isiflu Zonale Istivac Kaksoisrokote Dubbelvaccin Influenza (whole virus) Tetanus, polio Polio (inactivated) Influenza (whole virus) Influenza Kikhoste-Vaksine Pertussis Koplivac Kotipa Krztuscowi Ksztu Measles (Edmonston strain) Cholera, typhoid, paratyphoid Pertussis Pertussis Lancy Vaxina Smallpox Lavantuu Tirokote Typhoid Liomorbillo Liovaxs Lirugen LM – 3 RIT LM – 2 RIT Lteanas Imuna Lyssavac N M-M-Rvax M-M-Vax M-Vac Massern-Impfstoff SSW Massling MDPH-PA Measavac MenAfriVac Measles Smallpox Measles Measles, mumps, rubella (live) Measles, mumps (live) Tetanus (adsorbed) Rabies Measles, mumps, rubella Measles, mumps Measles (live) Chiron, Italy Sanofi Pasteur Dong Shin Pharm, Korea Dong Shin Pharm, Korea Imuna sp., Slovakia Berna Biotech, Europe Chiron, Europe Merck, Europe Serum Institute of India (Sii) Measles (live) Chiron, Germany Measles Anthrax Measles (Edmonston strain) Meningococcal A Conjugate Meningococcal Group A (polysaccharide) Meningococcal quadravalent Meningococcal Groups A & C (conjugate) Meningococcal Group C (conjugate) Meningococcal Group C (conjugate) Meningococcal Group C (conjugate) Meningococcal Group C (conjugate) Meningococcal Groups A, C, Y & W135 (polysaccharide) Meningococcal Groups A & C Meningococcal Group B Measles (Edmonston strain) Measles (Schwarz strain) Influenza (whole virus) Influenza (whole virus) Influenza Sweden Mencevax A Mencevax ACWY Mengivax A/C Meningitec Meningtec Meninvact Menjugate Menpovax 4 Menpovax A+C MeNZB Mesavac Mevilin-L MFV MFV-Ject Miniflu Diphtheria, tetanus (pediatric) July 2011, Minnesota Department of Health GSK Sanofi Pasteur, France Chiron, Europe Isi, Italy Sanofi Pasteur, Europe Natl. Public Health Institute, Finland Statens Institutt for Folkehelse, Norway Philips-Duphar, Australia Perum Bio Farma, Indonesia Poland Poland Swiss Serum and Vaccine Institute, Switzerland Central Pub Health La, Finland Pfizer, UK Africa SmithKline/RIT, Belgium GSK Sanofi Pasteur, Europe Wyeth, UK, Australia Wyeth, Canada Sanofi Pasteur Novartis Chiron, Europe Chiron, Italy Novartus, New Zealand Pfizer, UK Chiron, UK Servier, UK Sanofi Pasteur, Europe Schiapparelli, Italy Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 123 Trade Name Mo-Ru Viraten Antigen(s) Neotyf Nilgrip Measles, rubella Pneumococcal 17-valent (polysaccharide) BCG Measles, mumps (live) Measles (live) Measles, rubella (live) Measles immunoglobulin Measles, mumps, rubella (live) Measles (live) Mumps (live) Influenza (whole virus) Influenza Influenza Meningococcal Group C (conjugate) Pneumococcal 23-valent (polysaccharide) Typhoid (live, oral) Influenza Nivgrip Influenza (whole virus) NorHOMHerHTA Nothav Polio (inactivated) Hepatitis A Okavax Varicella (live) Optaflu Influenza (cell culture-based) Oral Virelon Pariorix Pavivac Polio (oral) Mumps (live) Mumps (live) Diphtheria, tetanus, acellular pertussis, Hib, polio Diphtheria, tetanus, acellular pertussis, Hib, polio Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, hepatitis B, Hib Diphtheria, tetanus, pertussis, polio, Hib OR Diphtheria, tetanus, pertussis, polio, hepatitis B Diphtheria, tetanus, pertussis, polio, Hib Measles, rubella Pneumococcal 23-valent (polysaccharide) Diphtheria, tetanus, pertussis, polio, Hib Polio (inactivated) Polio (live, oral, trivalent) Polio (oral) Moniarix Monovax / Monovac Mopavac Morbilvax Morubel Moruman Berna Morupar Movivac Mumaten Munevan Mutagrip Nasoflu Neis Vac-C Neumo Imovax Pediacel Penta PENT-HIBest Pentacel Pentacoq PentAct-HIB Pentavac Pentavalente Pentavalenti Pentaxim Pluserix Pneumopur POLIAcel Poliomyelite Polioral Polio Sabin 124 www.health.state.mn.us/immunize Manufacturer, Country Berna Biotech, Canada GSK, Europe Sanofi Pasteur, France Sevac, Czech Republic Chiron, Italy Chiron, Italy Berna, Switzerland Chiron, Italy Sevac, Czech Republic Berna Biotech, Switzerland Medeva Sanofi Pasteur, Germany GSK, Europe Baxter, Europe & Canada Sanofi Pasteur, Mexico Chiron, Italy CSL Nicolau Institute of Virology, Romania Russia Chiron, Italy Biken / Sanofi Pasteur, Japan & Europe Novartis, Europe, Iceland, Norway Chiron, Germany GSK, Mexico & Europe Sevac, Czech Republic Europe Sanofi Pasteur, Europe Sanofi Pasteur Sanofi Pasteur, Canada Sanofi Pasteur Sanofi Pasteur, Europe Sanofi Pasteur Mexico Italy Aventis Pasteur, France GSK, Mexico & Europe Chiron, Europe Sanofi Pasteur, Argentina France Novartis GSK, Europe Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Trade Name Antigen(s) Poloral Polio (oral) Prevenar Previgrip Primavax Priorix Priorix-Tetra Probivac-B Procomvax PRS R-HB Vaccine R-Vac Rabdomune Rabipur Rabivac Rasilvax RDCV Refortrix Repevax Revaxis Rimevax Rimparix RIT-LM-2 RIT-LM-3 Pneumococcal 7-valent (conjugate) Influenza Diphtheria, tetanus, hepatitis B Measles, mumps, rubella (live) Measles, mumps, rubella, varicella (live) Hepatitis B Hib, hepatitis B MMR Pneumococcal 23-valent (polysaccharide) Diphtheria, tetanus, pertussis, hepatitis B Diphtheria, tetanus, acellular pertussis, polio Diphtheria, tetanus, acellular pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio Diphtheria, tetanus, pertussis, Hib Diphtheria, tetanus, pertussis, polio Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, polio, Hib Diphtheria, tetanus, pertussis, Hib, Hepatitis B Hepatitis B (recombinant) Rubella (live) Rabies Rabies Rabies Rabies “Rabies Diploid Cell Vaccine” Diphtheria, tetanus (adult) Diphtheria, tetanus, pertussis, polio Tetanus, diphtheria, polio (adult) Measles (live, Schwarz strain) Measles, mumps (live) Measles, mumps (live) Measles, mumps, rubella (live) Rorvax Measles, mumps, rubella (live) Rosovax Rouvax Rubavax Rubeaten Rubellovac Rubilin Rudi-Rouvax Rudivax Sahia Sampar Rubella Measles (live) Rubella (live) Rubella (live) Rubella (live) Rubella (live) Measles, rubella (live) Rubella (live) Polio (live oral) Plague Pulmovax Q-Vac Quadracel QUADRAcel/Hibest Quadravax Quadruple Quatro-Virelon Quinivax-IN Quintuple Quinvaxem July 2011, Minnesota Department of Health Manufacturer, Country Swiss Serum and Vaccine Institute Wyeth, France Chiron, France Sanofi Pasteur, Europe GSK, Europe & Australia GSK, Europe Probiomed, Mexico Sanofi Pasteur, Europe Cuba Merck Serum Institute of India (Sii) Sanofi Pasteur, Mexico Sanofi Pasteur, Argentina GSK Mexico Chiron, Europe Valda Laboratori, Europe GSK, Mexico Novartis/Crucell Mitsubishi Chem Corp, Japan Serum Institute of India (Sii) Impdfstofwerke, Germany Chiron, Germany Chiron, Germany Chiron, Italy GSK Sanofi Pasteur Sanofi Pasteur (Europe) GSK, Mexico & Europe GSK, Europe Dong Shin Pharm, Korea Dong Shin Pharm, Korea Sanofi Pasteur, Europe & Brazil Ism, Italy Sanofi Pasteur, Europe Sanofi Pasteur, UK Berna Biotech, Europe Chiron, Germany Chiron, UK Sanofi Pasteur, France Sanofi Pasteur, France Multiple manufacturers Sanofi Pasteur, Indonesia Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 125 Trade Name Sandovac Serap Shanvac-B SMBV Sii Rabivax Sii Triple Antigen Stamaril Antigen(s) Subinvira Synflorix T. Polio Influenza Diphtheria, tetanus, pertussis Hepatitis B Rabies Rabies Diphtheria, tetanus, pertussis Yellow fever (live) Pneumococcal 23-valent (polysaccharide) Influenza (split virus) Pneumococcal (10-valent, conjugate) Tetanus, polio T.A.B. Typhoid, paratyphoid (A & B) T-Immun T-Vaccinol T-Wellcovax Tanrix Td-Pur Td-Virelon Te Anatoxal Telvaclptap Tet-Aktiv Tet-Tox Tetagrip Tetanus (adsorbed) Tetanus Tetanus Tetanus Tetanus, diphtheria (adult) Tetanus, diphtheria, polio Tetanus Tetanus Tetanus Tetanus Tetanus, influenza Tetamun SSW Tetanus (fluid, nonadsorbed) Tetamyn Tetano-difter Tetanus Tetanus, diphtheria Tetanol Tetanus (adsorbed) Tetanovac Tetanus Tetasorbat SSW Tetanus (adsorbed) Tetatox Tetavax Tetracoq 05 TetrAct-HIB Tetraxim Theracys Ticovac Tifovax Titifica TOPV Tetanus (adsorbed) Tetanus (adsorbed) Diphtheria, tetanus, pertussis, polio Diphtheria, tetanus, pertussis, Hib Diphtheria, tetanus, acellular pertussis, polio Diphtheria, tetanus, pertussis, hepatitis B Tetanus, diphtheria, pertussis, polio BCG Tick-borne encephalitis Typhoid (Vi polysaccharide) Typhoid and paratyphoid Polio (oral, trivalent) Trenin DPT Behring Diphtheria, tetanus, pertussis Streptopur Tetravac Acellulaire Tetravalenti 126 www.health.state.mn.us/immunize Manufacturer, Country Sandoz, Austria Perum Bio Farma, Indonesia Shantha, India Sanofi Pasteur, Europe Serum Institute of India (Sii) Serum Institute of India (Sii) Sanofi Pasteur, Europe Chiron, Europe Imuna, Czech Republic GSK, Europe, Australia SP (Canada) - Institute Pasteur, Tunisia - Egypt - Pharmaceutical Industries Corp., Burma Baxter, Germany Roehm Pharma, Germany Wellcopharm, Germany GSK, Europe Chiron, Europe Chiron, Europe Berna Biotech, Switzerland Yugoslavia Tropon-Cutter, Germany CSL Limited, Australia SP, France Veb Sachsisches Serumwerk, Germany Bioclon, Mexico Celltech Pharma Chiron, Sanofi Pasteur, Europe & Mexico Sanofi Pasteur, Mexico Veb Sachsisches Serumwerk, Germany Berna Biotech, Italy Sanofi Pasteur, Europe Sanofi Pasteur, France Sanofi Pasteur, Europe Sanofi Pasteur, Europe Italy Sanofi Pasteur, Europe Aventis Pasteur, Canada Baxter SA Sanofi Pasteur, Mexico Italy Multiple manufacturers Chiron Behring GmbH, Germany Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Trade Name Antigen(s) Tresivac Measles, mumps, rubella (live) Triacel Diphtheria, tetanus, acellular pertussis Triacelluvax Trimovax Tripacel Diphtheria, tetanus, acellular pertussis Measles, mumps, rubella (live) Diphtheria, tetanus, acellular pertussis Triple antigen Diphtheria, tetanus, pertussis Triple Sabin Triple Polio (live, oral) Diphtheria, tetanus, pertussis Triple viral Measles, mumps, rubella Triplice (VT) Triplice Viral (VTV) Diphtheria, tetanus, pertussis Measles, mumps, rubella Triplovax Measles, mumps, rubella Tritanrix Diphtheria, tetanus, whole-cell pertussis Diphtheria, tetanus, whole-cell pertussis, hepatitis B Diphtheria, tetanus, whole-cell pertussis, hepatitis B, Hib Diphtheria, tetanus (adsorbed), pertussis Diphtheria, tetanus (plain), pertussis Diphtheria, tetanus (adsorbed), pertussis Diphtheria, tetanus, pertussis, Hib Diphtheria, tetanus, pertussis Measles, mumps, rubella (live) Measles, mumps, rubella (live) Measles, mumps, rubella Pertussis BCG BCG Typhoid (Vi polysaccharide) Tritanrix-HB Tritanrix-HB-Hib Trivacuna Leti Trivax Trivax-AD Trivax-Hib Trivb Triviraten Trivivac Trivivax Tussitrupin Forte Tuvax Tyne Typherix Typhoparatyphoidique Typhoral-L Typh-Vax Manufacturer, Country Serum Institute of India (Sii) Sanofi Pasteur, Europe & Mexico Chiron, Europe Sanofi Pasteur, Sanofi Pasteur, Europe - Chowgule & Co., India - CSL Limited, Australia Mexico Cuba, Mexico - Mexico - Immunology Institute, Croatia Instituto Butantan, Brazil Instituto Butantan, Brazil Sanofi Pasteur, Europe & Brazil GSK GSK, Mexico GSK Laboratory Leti, Spain Chiron, UK Chiron, UK GSK, Europe Brazil Berna Biotech, Switzerland Sevac, Czech Republic Sanofi Pasteur, Mexico Staatliches Institut, Germany Japan BCG Laboratory, Japan Sweden GSK, Europe & Australia Typhoid and paratyphoid France Typhoid (Ty21a oral) Typhoid Berna Biotech, Germany CSL Limited, Australia Finlay Vacunas y Sueros, Cuba Finlay Vacunas y Sueros, Cuba Bioclon, Mexico Cantacuzino Institute, Romania Va-Diftet Diphtheria, tetanus Va-Mengoc-BC Meningococcal Groups B & C Vac-DPT Vaccin Difteric Adsorbit Vaccin Rabique Pasteur Vaccin Combinat Diftero-Tetanic Vaccin tuberculeux attenue lyophilize Diphtheria, tetanus, pertussis Diphtheria (adsorbed) Rabies Pasteur Vaccins Diphtheria, tetanus (adsorbed) Cantacuzino Institute, Romania BCG Sanofi Pasteur, France July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 127 Trade Name Vaccinum Morbillorum Vivum Vacina Dupla Vacina Triplice Vacina Triplice Viral Vacuna Doble Vacunol Vaksin Sampar Vaksin Cacar Vaksin Serap Vaksin Campak Kerig Vaksin Kotipa Antigen(s) Diphtheria, tetanus Diphtheria, tetanus, pertussis Measles, mumps, rubella Tetanus, diphtheria Tetanus Plague Smallpox Diphtheria, tetanus, pertussis Moscow Research Institute, Russia Instituto Butantan, Brazil Instituto Butantan, Brazil Brazil Instituto Biologico Argentino Temis-Lostato, Brazil Perum Bio Farma, Indonesia Indonesia Perum Bio Farma, Indonesia Measles (live) Perum Bio Farma, Indonesia Cholera, typhoid, paratyphoid A, B & C Rabies (purified vero cell) Hepatitis A, typhoid Cholera Hepatitis B Polio (inactivated) Polio (live, oral trivalent) Measles, mumps, rubella (live) Perum Bio Farma, Indonesia Institute of Immunology, Croatia GSK, Europe Behringwerke Aktiengesellischaft, Germany Institute of sera and Vaccine, Czech Republic GSK, Australia, New Zealand GSK, Europe & Mexico Finlay Vacunas & Sueros, Cuba Chiron, Europe Sanofi Pasteur, France Sanofi Pasteur, Europe & Australia Riker, UK Chiron, Italy Cantacuzino Institute, Romania Cantacuzino Institute, Romania Sanofi Pasteur, France Sanofi Pasteur, UK Duncan Flockhart, UK Ivax Pharmaceuticals, Mexico Chiron, Germany Chiron, Germany Merck, Finland Measles, mumps, rubella Sweden Polio (oral) Human Papillomavirus Diphtheria, tetanus, pertussis PT Biofarma, Indonesia Spanish Instituto Butantan, Brazil Measles, mumps, rubella Brazil Measles (live) Vamoavax Measles, mumps (live) Varicella-RIT Varicella Varicellon Zaricella zoster immunoglobulin Varie Smallpox (lyophilized) Varilrix Varirix Varicella (live, Oka strain) Varicella (live, Oka strain) Vax-Tet Tetanus Vaxem-Hib Vaxicoq Hib (polysaccharide) Pertussis (adsorbed) Vaxigrip Influenza Vaxihaler-Flu Vaxipar Influenza (inhaler) Mumps (live) VCDT Diphtheria, tetanus (pediatric) VDA Vaccin Difteric Adsorbit Verorab ViATIM Vibriomune Viralinte Virelon C Virelon T 20 Virivac Virovac Massling, Perotid, Rubella Vopix VPH V T (Vacine Triplice) V T V (Vacina Triplice Viral) Diphtheria VVR Measles (live) Welltrivax Trivalente X-Flu Diphtheria, tetanus, pertussis Influenza 128 Manufacturer, Country www.health.state.mn.us/immunize Cantucuzino Institute, Romania Spain CSL Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Trade Name Zaantide Zaantite Zaditeadvax Zaditevax Zamevax A+C Zamovax Zamruvax Zapavax Zaruvax Zatetravax Zatevax Zatribavax Zatrivax July 2011, Minnesota Department of Health Antigen(s) Diphtheria antitoxin Tetanus antitoxin Diphtheria, tetanus Diphtheria, tetanus Meningococcal Groups A & C (polysaccharide) Measles (live) Measles, rubella (live) Mumps Rubella (live) Diphtheria, tetanus, pertussis, parapertussis Tetanus Diphtheria, tetanus, pertussis Measles, mumps, rubella (live) Manufacturer, Country Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia Imunoloski Zavod, Croatia February 2012 Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 129 Vaccines for the international traveler Traveling outside the United States? Plan ahead for your international travel shots Where can I get information on international travel shots? The Minnesota Department of Health does not provide international travel health consultation or international travel shots. Information on international travel shots and other travel health issues including disease and concerns about food and water supplies is available by country from the Centers for Disease Control and Prevention (CDC): x CDC Travel website www.cdc.gov/travel How soon before I travel do I have to get the vaccines I need? Start planning now. Some vaccines take up to six months for the entire series. What vaccines will I need? The international travel vaccines you need depend on your travel destination, age, current medical condition, occupation and lifestyle. Where do I go to get international travel shots? It depends. If you are going to Europe, Canada, Mexico, Japan, Australia, or New Zealand, your health care provider should be able to give you the shots you need. If you are going to any other country than those just listed, an international travel health clinic is your best resource. Where can I find an international travel health clinic? International travel health clinics in Minnesota are listed on the back of this fact sheet. Do I need yellow fever vaccine? If you are going to Africa, Central America, or South America, you may need yellow fever vaccine or other vaccines your health care provider might not have. International travel health clinics are the only places that can give yellow fever vaccine. Are your routine immunizations up to date? Don’t just get your international travel shots! It’s a good idea for adults and children to be up to date with routine vaccines before they leave the country. Children. Children are vaccinated against 12 diseases in the United States. If you aren’t sure your children are up to date with their routine shots, call their health care provider. Adults. Adults need routine vaccines too! If you aren’t sure you are up to date, call your health care provider. Other information for the international traveler The State Department’s travel website includes travel warnings, information on how to get visas and passports, and a wealth of other international travel tips. This information is available at www.state.gov/travel. Visit MDH’s website This fact sheet and a list of international travel health clinics in Minnesota are available on the Web at www.health.state.mn.us/immunize under “For Travelers.” International travel health clinics in Minnesota (see back) 叝叝叝叝叝 Immunization Program P.O. Box 64975 St. Paul, MN 55164-0975 651-201-5414 or 1-877-676-5414 www.health.state.mn.us/immunize (MDH 10/2012) Available on the web at: www.health.state.mn.us/divs/idepc/immunize/travel/travelshots.html 130 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 International travel health clinics serving Minnesota residents The international travel health clinics listed below are authorized to administer yellow fever vaccine. They also provide a variety of other pre- and post-travel services to travelers. Most international travel clinics require an appointment and may require you to see a health care provider. ALWAYS call first. Greater Minnesota clinics: Mayo Health System Austin 1000 1st Drive NW Austin, MN 55912 Phone: 507-433-7351 Sanford Clinic - Bemidji 1233 34th Street NW Bemidji, MN 56601 Phone: 218-333-4944 Essentia Health Brainerd Clinic 2024 S. Sixth Street Brainerd, MN 56401 Phone: 218-828-7100 Parkview Clinic 1400 First Street. NE New Prague, MN 56071 Phone: 952-758-2535 Park Nicollet Clinic – Burnsville 14000 Fairview Drive Burnsville, MN 55337 Phone: 952-993-3131 New Ulm Medical Center 1324 5th Street N. New Ulm, MN 56073 Phone: 507-233-1000 Allina Medical Clinic/ Crossroads Chaska 111 Hundertmark Road, Suite 220 Chaska, MN 55318 Phone: 952-448-2050 Allina Medical Clinic - Northfield 1400 Jefferson Road Northfield, MN 55057 Phone: 507-663-9000 800-272-0508 Cambridge Medical Center 701 S. Dellwood Avenue Cambridge, MN 55008 Phone: 763-689-8700 Northside Medical Center Ortonville Area Health Services 450 Eastvold Avenue Ortonville, MN 56278 Phone: 320-839-6157 St. Luke’s Infectious Disease and Travel Center 1001 East Superior Street, L201 Duluth, MN 55805 Phone: 218-249-7990 Owatonna Clinic Mayo Health System 2200 26th Street NW Owatonna, MN 55060 Phone: 507-444-5020 Essentia Health Duluth Clinic 400 East Third Street Duluth, MN 55805 Phone: 218-786-3737 Mayo Clinic Tropical Travel & Medicine 200 First Street SW Rochester, MN 55905 Phone: 507-255-7763 Allina Medical Clinic – Faribault 100 State Avenue Faribault, MN 55021 Phone: 507-334-3921 Hutchinson Medical Center 3 Century Avenue Hutchinson, MN 55350 Phone: 320-587-2020 Immanuel St. Josephs Mayo Health System 1015 Marsh Street Mankato, MN 56002 Phone: 507-385-4700 Lake Region Healthcare Clinic Services 615 Mill Street S. Fergus Falls, MN 56537 Phone: 218-739-2221 Mankato Clinic 1230 East Main Street Mankato, MN 56001 Phone: 507-625-1811 Olmsted Medical Center 210 9th Street SE Rochester, MN 55904 Phone: 507-288-3443 CentraCare Clinic—Family Medicine—Health Plaza 1900 CentraCare Circle St. Cloud, MN 56303 Phone: 320-229-4917 Affiliated Community Medical Center 101 Willmar Avenue SW Willmar, MN 56201 Phone: 320-231-5070 Twin Cities metropolitan area clinics: MD Physicals, Inc. 14135 Cedar Avenue, Suite 300 AppleValley, MN 55124 Phone: 952-431-9655 Allina Medical Clinic/ Coon Rapids Coon Rapids Medical Center 9055 Springbrook Dr. Coon Rapids, MN 55433 Phone: 763-780-9155 N.W. Family Physicians 5700 Bottineau Boulevard Crystal, MN 55429 Phone: 763-287-6500 Passport Health 6700 France Avenue S., Suite 150 Edina, MN 55435 Phone: 952-922-9089 Axis Medical Center 1801 Nicollet Avenue S. Minneapolis, MN 55403 Phone: 612-823-2947 Airport Medical Clinic 7550 34th Avenue S. Minneapolis, MN 55450 Phone: 612-727-1167 Boynton Health Services 410 Church Street SE Minneapolis, MN 55455 Phone: 612-625-3222 Crown Medical Center 1925 1st Avenue S. Minneapolis, MN 55403 Phone: 612-871-4354 Fairview Uptown Clinic 3033 Excelsior Boulevard, Suite 275 Minneapolis, MN 55416 Phone: 612-827-4751 Hennepin Faculty Associates Internal Medicine 825 S. 8th Street, Suite 206 Minneapolis, MN 55404 Phone: 612-347-7534 Continued on next page Æ Available on the web at: www.health.state.mn.us/divs/idepc/immunize/travel/travelshots.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 131 International Travel Clinic AbbottNorthwestern 2545 Chicago Avenue S., Suite 200 Minneapolis, MN 55405 Phone: 612-863-1939 NorthPoint Health and Wellness Center 1313 Penn Avenue N. Minneapolis, MN 55411 Phone: 612-543-2522 Allina Medical Clinic/Woodbury 8675 Valley Creek Road Woodbury, MN 55124 Phone: 651-501-3000 Clinics near Minnesota borders: North Iowa Mercy Internal Medicine Mason City, IA Phone: 800-756-4423 Minneapolis VA Medical Center U.S. Veterans only, 3-D Clinic One Veterans Drive Minneapolis, MN 55417 Phone: 612-467-1100 Fargo/Cass Public Health Department Fargo, ND Phone: 701-298-6938 International Travel Clinic Ridgedale Office Center 13911 Ridgedale Drive Suite. 484 Minnetonka, MN 55305 Phone: 952-405-8812 Where can I get travel immunization information? The Minnesota Department of Health does not provide travel health consultation or travel vaccines. Use resources from the Centers for Disease Control and Prevention to learn about travel vaccines and other travel health issues: CDC’s travel website (www.cdc.gov/travel). If you have insurance, call your health plan’s member services office to see if you are covered for your travel vaccines. Altru Main Clinic Grand Forks, ND Phone: 701-780-6234 Sanford Health Sioux Falls, SD 605-328-8120 Fairview RidgeValley Medical Center 4151 Willowwood Street SE Prior Lake, MN 55372 Phone: 952-226-2600 Gunderson Lutheran Medical Center LaCrosse, WI Phone: 800-362-9567 Quello Clinic - Savage 6350 W 143rd Street, Suite. 102 Savage, MN 55378 Phone: 952-428-0200 St. Croix Regional Medical Center St. Croix Falls, WI Phone: 800-828-3627 Complete Home Health Services 4001 Stinson Boulevard, LL32 St. Anthony, MN 55421 Phone: 612-788-2273 HealthPartners Travel & Tropical Medicine Center 5100 Gamble Drive Suite. 100 St. Louis Park, MN 55416 Phone: 952-967-7978 Park Nicollet Clinic 3800 Park Nicollet Boulevard St. Louis Park, MN 55416 Phone: 952-993-3131 HealthPartners Travel & Tropical Medicine Center 401 Phalen Boulevard St. Paul, MN 55101 Phone: 952-967-7978 St. Paul Ramsey County Department of Public Health 555 Cedar Street St. Paul, MN 55101 Phone: 651-266-1234 Stillwater Medical Group 1500 Curve Crest Boulevard Stillwater, MN 55082 Phone: 651-439-1234 Minnesota Department of Health, Rev October 2012 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/travel/travelshots.html 132 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Provider’s Quick Reference on Minnesota’s Immunization Laws Be sure you have up-to-date information on Minnesota’s School Immunization Law by visiting the MDH website at www.health.state.mn.us/immunize. To help prevent over-immunization and missed opportunities, providers are encouraged to enroll in the Minnesota Immunization Information Connection (MIIC) web-based application, which allows immunization providers to enter and view all immunizations given to their patients. Immunizations Required for Licensed Child Care Facilities and School Grades K - 12 Minnesota Statutes, section 121A.15, subd. 1 Age/Grade of Child1 PCV-13 Birth to 2 months 2 months to 15 months 15 months to kindergarten age Pre-kindergarten (3-4 years) Kindergarten st 1 grade through 6 years 7 years through grade 6 None None Age 3 appropriate Age appropriate Age 3 appropriate 1 None 1 None None 5 None 5 6 3 8 Grade 7 Grades 8 through 12 1 2 3 4 5 6 7 8 9 10 11 Number of Doses Required by Vaccine Type DTaP/ Hib DTP/ Polio MMR Varicella2 DT/Tdap/Td None None None None None Age appropriate Age appropriate None None None 4 Age appropriate Age appropriate 1 1 None 4 4-5 1 1 None 4 2 2 3 7 1 None None 3 1 None None 3 2 2 11 2 None None None None Hep B 5 3-4 4 None None 3 plus booster 9 None None 3 plus booster 9 3 5 2-3 10 None A vaccine dose administered four or fewer days before the minimum age required by law is considered valid. As of September 1, 2010, only a health care provider (physician, nurse practitioner, or physician assistant) can verify history of chickenpox disease for a child entering child care or school. Pneumococcal vaccine is required for children 2 to 24 months of age. Minnesota law requires children enrolled in a child care facility have at least one dose of Hib vaccine given at or after 12 months of age; however it is always recommended to vaccinate children according to age appropriate recommendations. MDH recommends that school “boosters” for DTaP/DTP/DT and polio be administered before entrance to kindergarten. The fifth dose of DTaP is not required if the fourth DTaP was administered after the fourth birthday. The fourth dose of polio vaccine is not required if the third dose of polio was administered after the fourth birthday. Pertussis vaccine is not required of students 7 years of age or older. If a child in grades 7 through 12 received a Tdap/Td booster after their seventh birthday but before age 11 they are exempt until 10 years have elapsed since that dose was given. A two-dose hepatitis B adolescent schedule is acceptable; however, it must be clearly documented that the two-dose product, such as Recombivax, was given. Students age 18 years or older are exempt from the polio vaccine requirement. Exemptions to the Child Care and K-12 School Immunization Law Minnesota Statutes, 121A.15, Section 3 For a medical contraindication to the required vaccine(s), including anaphylactic reaction to a previous dose or to vaccine component(s), the parent/guardian must have a signed statement by a physician specifying the vaccine(s). For laboratory evidence of immunity to a disease covered by the law, the parent/guardian must have a signed statement by a physician specifying the vaccine(s). For conscientious objection by a parent or legal guardian to one or more of the vaccine(s), the parent/guardian must have a notarized statement that specifies the vaccine(s) and is signed by the parent/guardian. MDH, Immunization Program (4/11) Page 1 of 2 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/laws/qreflaws.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 133 Immunizations Required for Post-Secondary Schools and Colleges Minn. Stat. Section 135.14 Required Vaccines Number of Doses Tetanus and diphtheria (Td or Tdap) One dose given in the 10 years prior to initial enrollment Measles, mumps, and rubella (MMR) One dose given on or after the first birthday (a second dose is recommended) Recommended Vaccines Number of Doses Meningococcal Medically acceptable standard Hepatitis A and B Medically acceptable standard Exemptions to Post-Secondary School and College Immunization Law Minnesota Statutes, section 135.14, subd. 3 A person who graduated from a Minnesota high school in 1997 or later is exempt from these requirements because they will already have met them as a high school student. For a medical contraindication to required vaccine(s), including anaphylactic reaction to a previous dose or to vaccine component(s), the patient or parent/guardian must have a signed statement by a physician specifying the vaccine(s). For laboratory evidence of immunity to a disease covered by the law, the patient/parent/guardian must have a signed statement by a physician specifying the vaccine(s). For conscientious objection by the patient/parent/legal guardian to one or more of the vaccines, the patient/parent/guardian must have a notarized statement specifying the vaccine(s) and signed by the patient/parent/guardian. Related Legal Requirements for Child Care, Schools, and Colleges Exemption Information: It is a state law that any written materials given to parents of pediatric patients about vaccines required for grades K-12 or child care must contain information on legal exemptions. The exemption information must be in the same font size and style and on the same page as the requirements. Vaccine Information Statements: It is a federal requirement that providers must give a copy of the Vaccine Information Statement (VIS) to any patient/parent/guardian receiving a vaccine. Immunization Program P.O. Box 64975 St. Paul, MN 55164-0975 651-201-5503 or 1-800-657-3970 www.health.state.mn.us/immunize (4/11) Page 2 of 2 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/laws/qreflaws.html 134 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Guide to Contraindications and Precautions to Commonly Used Vaccines Make sure you are aware of all possible contraindications and precautions for health conditions that might preclude a particular vaccine. Also, don’t miss opportunities to vaccinate because of misperceptions of a contraindication or precaution. Remember to screen patients each time you vaccinate because responses to the questions may change. True Contraindications and Precautions Not True (give vaccines) Diphtheria, tetanus, pertussis (DTaP) Vaccine Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components • Encephalopathy (e.g., coma, decreased level of consciousness, prolonged seizures) without an identified cause within 7 days of administration of prior dose of DTP or DTaP Precautions: • Moderate or severe acute illness with or without fever • Fever of 105°F or greater ( 40.5°C or greater) within 48 hours after a previous dose of DTP or DTaP • Progressive neurological disorder, including infantile spasms, uncontrolled epilepsy, progressive encephalopathy: defer DTaP until neurologic status clarified and stabilized • Collapse or shock-like state (hypotonic hypo-responsive episode) within 48 hours of receiving a previous dose of DTP/DTaP • Seizure within 3 days of receiving a previous dose of DTP/DTaP • Persistent, inconsolable crying lasting 3 hours or more within 48 hours after receiving a previous dose of DTP/DTaP • Guillain-Barré syndrome (GBS) within 6 weeks after a previous dose of tetanus toxoid-containing vaccine • History of arthus-type reaction following a previous dose of tetanus-toxoid containing vaccine; defer until at least 10 years from previous dose (Arthus-type reactions are rare in childhood DTaP series.) • Temperature less than 105°F or 40.5°C within 48 hours of receiving DTaP or DTP • Fussiness or mild drowsiness after a previous dose of DTP/DTaP • Family history of seizures • Family history of sudden infant death syndrome • Family history of an adverse event after DTP or DTaP administration • Stable neurological conditions (e.g., cerebral palsy, well controlled convulsions, developmental delay) Diphtheria, tetanus, (DT and Td) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components Precautions: • Moderate or severe acute illness with or without fever • Guillain-Barré syndrome (GBS) within 6 weeks after a previous dose of tetanus toxoid-containing vaccine • History of Arthus-type reaction following a previous dose of tetanus-toxoid containing vaccine; defer until at least 10 years from previous dose Tetanus, diphtheria, pertussis (Tdap) • See page 3, tetanus, diphtheria, pertussis (Tdap) Haemophilus influenzae type B (Hib) Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components • Age less than 6 weeks Precaution: • Moderate or severe acute illness with or without fever Hepatitis A (HepA) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components Precautions: • Moderate or severe acute illness with or without fever • Pregnancy Hepatitis B (HepB) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components Precautions: • Moderate or severe acute illness with or without fever • Infant weighing less than 2000 grams1 • Pregnancy • Autoimmune disease (e.g., systemic lupus erythematosis, rheumatoid arthritis) Immunization Program P.O. Box 64975 St. Paul, MN 55164-0975 651-201-5503, 1-800-657-3970 www.health.state.mn.us/immunize IC#141-0649 (05/11) Page 1 of 4 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/vaccine.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 135 Vaccine True Contraindications and Precautions Human Papillomavirus (HPV2, HPV4) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components Precautions: • Moderate or severe acute illness with or without fever • Pregnancy • • • • • Inactivated polio vaccine (IPV) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) to previous dose or to a vaccine component Precautions: • Moderate or severe acute illness with or without fever • Pregnancy • Previous receipt of oral polio vaccine (OPV) Influenza, injected trivalent (TIV) Contraindication: • Severe allergic reaction (e.g., anaphylaxis) to previous dose or to a vaccine component, including egg protein Precautions: • Moderate or severe acute illness with or without fever • Guillain-Barré syndrome (GBS) within 6 weeks after a previous dose of influenza vaccine Contraindications: • Severe allergic reaction (e.g., anaphylaxis) to previous dose or to a vaccine component, including egg protein • Aspirin therapy in children and adolescents • Known severe immunodeficiency (e.g., hematologic and solid tumors, congenital immunodeficiency, long term immunosuppressive therapy4 including chemotherapy, severely symptomatic HIV infection) • Pregnancy Precaution: • Moderate or severe acute illness with or without fever • Children with recurrent wheezing or asthma • Guillain-Barré syndrome (GBS) within 6 weeks after a previous dose of influenza vaccine • Persons with chronic medical conditions for which yearly influenza vaccination is recommended should not receive LAIV • Receipt of specific influenza antivirals (i.e., amantadine, rimantadine, or oseltamivir, or zanamivir) 48 hours before vaccination; if possible delay resumption of these antiviral drugs for 14 days after vaccination. • Non-systemic allergy to latex, thimerosal, or egg • Current administration of coumadin (warfarin) or aminophylline Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component • Known severe immunodeficiency (e.g., hematologic and solid tumors, congenital immunodeficiency, long term immunosuppressive therapy4 including chemotherapy, severely symptomatic HIV infection5) • Within 24 months of a hematopoietic stem cell transplant (HSCT) • Pregnancy Precautions: • Moderate or severe acute illness with or without fever • Recent (within 11 months) receipt of antibody-containing blood product (specific interval depends on product)6 • History of thrombocytopenia or thrombocytopenic purpura • • • • Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component • Known severe immunodeficiency (e.g., hematologic and solid tumors, congenital immunodeficiency, long term immunosuppressive therapy4 including chemotherapy, severely symptomatic HIV infection5) • Within 24 months of a hematopoietic stem cell transplant (HSCT) • Pregnancy Precautions: • Moderate or severe acute illness with or without fever • Personal or family history of seizures • Recent (within 11 months) receipt of antibody-containing blood product (specific interval depends on product)6 • History of thrombocytopenia or thrombocytopenic purpura • Receipt of specific antivirals (i.e., acyclovir or valacyclovir) 24 hours before vaccination; if possible delay resumption of these antiviral drugs for 14 days after vaccination. • • • • Influenza, live attenuated (LAIV)3 Measles, mumps, rubella (MMR)3 Measles, mumps, rubella, varicella (MMRV)3 Not True (give vaccines) Previous HPV infection2 Immunosuppression Breastfeeding History of genital warts Previous questionable or abnormal PAP test • Immunodeficient family member or household contact • Pregnant or breastfeeding family member or household contact • Breastfeeding • Health care workers (those that care for patients in protective isolation should receive a TIV or defer care for 7 days following LAIV) • Contacts of persons with chronic medical conditions • • • • • • • • • • Positive tuberculin skin test Simultaneous TB skin testing7 Breastfeeding Pregnancy of recipient’s mother or other close or household contact Recipient is female of childbearing-age Immunodeficient family member or household contact Asymptomatic or mildly symptomatic HIV infection5 Allergy to eggs Receipt of RSV monoclonal antibody (Synagis) Positive tuberculin skin test Simultaneous TB skin testing7 Breastfeeding Pregnancy of recipient’s mother or other close or household contact Recipient is female of childbearing-age Immunodeficient family member or household contact8 Asymptomatic or mildly symptomatic HIV infection5 Allergy to eggs Receipt of RSV monoclonal antibody (Synagis) MDH Immunization Program IC#141-0649 (05/11) Page 2 of 4 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/vaccine.html 136 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Vaccine True Contraindications and Precautions Meningococcal, Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to conjugate a vaccine component (MCV) Precaution: • Moderate or severe acute illness with or without fever Not True (give vaccines) • History of Guillain-Barré syndrome (GBS) Meningococcal, Contraindication: polysaccharide • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component (MPSV) Precaution: • Moderate or severe acute illness with or without fever Pneumococcal, Contraindication: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose of conjugate PCV7, PCV13 or any diphtheria containing vaccine or to their vaccine (PCV) components Precaution: • Moderate or severe acute illness with or without fever Pneumococcal, Contraindication: polysaccharide • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component (PPSV) Precaution: • Moderate or severe acute illness with or without fever • History of pneumonia or previous invasive pneumococcal disease Rotavirus (RV1, RV5) Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components • Severe Combined Immunodeficiency (SCID) Precautions: • Moderate or severe acute illness with or without fever • Chronic gastrointestinal disease • Altered immunocompetence other than SCID • History of intussusception • Infants with spina bifida or bladder exstrophy (RV1 only) Tetanus, diphtheria (Td) Tetanus, diphtheria, pertussis (Tdap) • See page 1, diphtheria, tetanus, (DT and Td) Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components • Encephalopathy (e.g., coma, decreased level of consciousness, prolonged seizures) without an identified cause within 7 days of administration of prior dose of DTP, DTaP, or Tdap Precautions: • Moderate or severe illness with or without fever • Guillain-Barré syndrome (GBS) within 6 weeks after previous dose of tetanus toxoid-containing vaccine • Progressive or unstable neurologic disorder, uncontrolled seizures or progressive neuropathy until stabilized • History of Arthus-type reaction following a previous dose of tetanus-toxoid containing vaccine; defer until at least 10 years from previous dose • Less than 10 years since previous dose of Td • Temperature less than 105°F or 40.5°C within 48 hours of receiving DTaP or DTP • Collapse or shock within 48 hours of receiving DTaP or DTP • Persistent, inconsolable crying lasting more than 3 hours within 48 hours of receiving DTaP or DTP • History of severe limb swelling after receiving DTaP or DTP • Stable neurological conditions (e.g., cerebral palsy, well controlled convulsions, developmental delay) • History of bronchial neuritis • Non-systemic allergy to latex • Immunosuppression • Breastfeeding Varicella (VAR)3 Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to a vaccine component • Known severe immunodeficiency (e.g., hematologic and solid tumors, congenital immunodeficiency, long term immunosuppressive therapy4 including chemotherapy, severely symptomatic HIV infection5) • Within 24 months of a hematopoietic stem cell transplant (HSCT)9 • Pregnancy Precautions: • Moderate or severe acute illness with or without fever • Recent (within 11 months) receipt of antibody-containing blood product (specific interval depends on product)6 • Receipt of specific antivirals (i.e., acyclovir, famciclovir, or valacyclovir) 24 hours before vaccination, if possible; delay resumption of these antiviral drugs for 14 days after vaccination. • Pregnancy of recipient’s mother or other close or household contact • Immunodeficient family member or household contact8 • Asymptomatic or mildly symptomatic HIV infection5 • Humoral immunodeficiency (e.g.,agammaglobulinemia) • Receipt of RSV monoclonal antibody (Synagis) • Immunodeficient family member or household contact • Mild diarrheal disease • Prematurity • Pregnant family member or household contact • Receipt of RSV monoclonal antibody (Synagis) MDH Immunization Program IC#141-0649 (05/11) Page.3 of 4 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/vaccine.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 137 Vaccine Zoster (ZOS)3 True Contraindications and Precautions Contraindications: • Severe allergic reaction (e.g., anaphylaxis) after a previous dose or to their vaccine components • Primary or acquired immunodeficiency (e.g., leukemia, lymphoma, AIDS or symptomatic HIV, long term immunosuppressive therapy4, receiving chemotherapy for malignancy, undergoing stem-cell transplantation, receiving immune mediators or modulators) • Pregnancy Precautions: • Moderate or severe acute illness with or without fever • Receipt of specific antivirals (i.e., acyclovir or valacyclovir) 24 hours before vaccination, if possible; delay resumption of these antiviral drugs for 14 days after vaccination. What is a contraindication? A contraindication to a vaccine is a condition in a patient that greatly increases the chance of a serious adverse reaction. Generally, a vaccine should not be given if someone has a contraindication to that vaccine. Permanent contraindications to vaccine and for which specific vaccines should not be given: y A history of a severe allergic reaction (e.g., anaphylaxis) to a previous dose of a specific vaccine or a component of that vaccine y Specific to DTaP or Tdap: encephalopathy without a known cause occurring within seven days of a dose of any pertussis-containing vaccine is a permanent contraindication for DTaP or Tdap What is a severe allergic reaction (e.g., anaphylaxis)? Sudden or gradual onset of generalized itching, redness, or hives; swelling of the lips, face, or throat; bronchospasm (wheezing); shortness of breath; shock; abdominal cramping; or cardiovascular collapse. There are two temporary contraindications to live attenuated viral vaccines where vaccines should be given after these temporary conditions no longer exist: y Immunosuppression (in most cases) y Pregnancy The following are NOT a contraindication or precaution to administration of any vaccine. Give vaccines: • Mild acute illness with or without fever • Mild to moderate local reaction (swelling, redness, soreness); fever less than 105°F or 40.5°C after prior dose • Lack of prior physical examination in well-appearing person • On antibiotics • Convalescent phase of illness Footnotes 1. 2. 3. 4. Not True (give vaccines) • Short-term, low-dose, or local (e.g., topical or non-systemic administration) corticosteroid therapy4 • Receipt of blood products • History of zoster not a consideration for vaccination • Contacts of patients with chronic diseases or altered immunocompetence • Low-dose treatment for rheumatoid arthritis, psoriasis, polymyositis, sarcoidosis, inflammatory bowel disease, or other conditions10 • Premature birth (hepatitis B vaccine is an exception in certain circumstances)1 • Recent exposure to an infectious disease • Allergy to products not in the vaccine • What is a local allergy reaction? Onset of itching or swelling localized to the injection site or site of exposure. Usually not a contraindication to vaccination. What is a precaution? A precaution is a condition in a patient that may increase the chance of a serious adverse reaction if vaccine is given, or may compromise the ability of the vaccine to produce immunity. Under normal circumstances, vaccines should be deferred when a permanent or temporary precaution exists, but sometimes the benefits outweigh the risks. There are two common temporary precautions to vaccines: y Moderate or severe acute illness (a precaution that applies to all vaccines) y Recent receipt of an antibody-containing blood product such as immune globulin (e.g., MMR, MMRV, and varicella) When to give a vaccine despite a precaution: In general, when a precaution exists, a dose of vaccine is not recommended. However, there may be situations when the benefit of vaccine outweighs the risk, and the provider may choose to give the vaccine. For example, a fever of 105°F / 40.5°C or greater within 48 hours after a previous dose of DTP or DTaP vaccine is considered a precaution to giving subsequent doses of pertussis vaccine to a child. But, if the child were at high risk of pertussis infection (e.g., a pertussis outbreak in the community), a provider may choose to vaccinate the child and treat the adverse reaction if it occurs. HIV-infected children may receive MMR and varicella vaccines if their CD4 T-lymphocyte count is greater than 15 percent. 6. For details on receipt of anitbody-containing blood product see page 39 of ACIP’s General Recommendations on Immunization in the January 28, 2011 MMWR at www.cdc.gov/ vaccines/pubs/ACIP-List.htm. 7. Vaccination with measles-containing vaccine can temporarily suppress tuberculin reactivity. However, measles-containing vaccine can be given on the same day as tuberculin skin testing. If not done on the same day postpone the skin test for 4 or more weeks after the vaccination. If the skin test is urgent do it with the understanding that the vaccine might reduce reactivity. 8. If a patient develops a presumed vaccine-related rash 7-25 days after receiving varicella-containing vaccine, they should avoid direct contact with immunocompromised persons for the duration of the rash. 9. Providers should assess immune status and risk of varicella on a case by case basis to determine need for vaccine before 24 months. 10. Low dose treatment is defined as 0.4 mg/kg/week or less of methotrexate, 0.3 mg/kg/day or less of azathioprine, or 1.5 mg/ kg/day or less of 6-mercaptopurine. 5. Defer hepatitis B vaccination for infants weighing less than 2,000 grams if the mother is documented to be HBsAg negative at the time of the infant’s birth. Start vaccinating these infants at age 1 month (28 days). For infants born to HBsAg-positive women, give HBIG and hepatitis B vaccine within 12 hours of birth regardless of weight and give 3 additional doses starting at 28 days and using a 0, 1-2, 6 month interval schedule. Unvaccinated sexually active women and those with a previous HPV infection may not receive the full benefit of the vaccine if they were already infected with an HPV type found in the vaccine. Live virus vaccines can be given at the same visit. However, if not given at the same visit, they should be separated by at least 28 days. Immunosuppressive steroid dose is defined as 2 weeks or more of 20 mg/day or 2 mg/kg/day or more of prednisone or equivalent. Non-immunosuppressive steroid dose is defined as either short-term (less than 2 weeks) or low-to-moderate dose (less than 20 mg/day or less than 2 mg/kg/day) of prednisone or equivalent. MDH Immunization Program IC#141-0649 (05/11) Page 4 of 4 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/hcp/vaccine.html 138 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 *>ÌiÌÊ>i\Ê Ê>ÌiÊvÊLÀÌ \Ê (mo.) (yr.) (day) Screening Checklist for Contraindications to Vaccines for Children and Teens For parents/guardians: The following questions will help us determine which vaccines your child may be given today. If you answer “yes” to any question, it does not necessarily mean your child should not be vaccinated. It just means additional questions must be asked. If a question is not Don’t clear, please ask your healthcare provider to explain it. Yes No Know 1. Is the child sick today? 2. Does the child have allergies to medications, food, a vaccine component, or latex? 3. Has the child had a serious reaction to a vaccine in the past? 4. Has the child had a health problem with lung, heart, kidney or metabolic disease (e.g., diabetes), asthma, or a blood disorder? Is he/she on long-term aspirin therapy? 5. If the child to be vaccinated is between the ages of 2 and 4 years, has a healthcare provider told you that the child had wheezing or asthma in the past 12 months? 6. If your child is a baby, have you ever been told he or she has had intussusception? 7. Has the child, a sibling, or a parent had a seizure; has the child had brain or other nervous system problems? 8. Does the child have cancer, leukemia, HIV/AIDS, or any other immune system problem? 9. In the past 3 months, has the child taken medications that weaken their immune system, such as cortisone, prednisone, other steroids, or anticancer drugs, or had radiation treatments? 10. In the past year, has the child received a transfusion of blood or blood products, or been given immune (gamma) globulin or an antiviral drug? 11. Is the child/teen pregnant or is there a chance she could become pregnant during the next month? 12. Has the child received vaccinations in the past 4 weeks? ÀÊV«iÌi`ÊLÞ\ ___________________________________________ ÊÊÊÊ>Ìi\_________________ ÀÊÀiÛiÜi`ÊLÞ\ÊÊ ___________________________________________ ÊÊÊÊ>Ìi\_________________ Did you bring your child’s immunization record card with you? yes no It is important to have a personal record of your child’s vaccinations. If you don’t have one, ask the child’s healthcare provider to give you one with all your child’s vaccinations on it. Keep it in a safe place and bring it with you every time you seek medical care for your child. Your child will need this document to enter day care or school, for employment, or for international travel. /iV V>ÊVÌiÌÊÀiÛiÜi`ÊLÞÊÌ iÊ iÌiÀÃÊvÀÊÃi>ÃiÊ ÌÀÊ>`Ê*ÀiÛiÌ ÜÜܰÕâi°À}ÉV>Ì}°`É«{äÈä°«`vÊÊUÊÊÌiÊ*{äÈäÊÊ£äÉ£Ó® IÕâ>ÌÊVÌÊ >ÌÊUÊ£xÇÎÊ-iLÞÊÛi°ÊUÊ-̰Ê*>Õ]Ê Êxx£ä{ÊUÊÈx£®ÊÈ{Çää ÊUÊÜÜܰÕâi°À}ÊUÊÜÜܰÛ>VVivÀ>̰À} July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 139 Information for Health Professionals about the Screening Checklist for Contraindications (Children & Teens) Are you interested in knowing why we included a certain question on the screening checklist? If so, read the information below. If you want to find out even more, consult the references listed at the bottom of this page. 1. Is the child sick today? [all vaccines] There is no evidence that acute illness reduces vaccine efficacy or increases vaccine adverse events (1, 2). However, as a precaution with moderate or severe acute illiÃÃ]Ê>ÊÛ>VViÃÊà Õ`ÊLiÊ`i>Þi`ÊÕÌÊÌ iÊiÃÃÊ >ÃÊ«ÀÛi`°Ê`ÊiÃÃiÃÊÃÕV Ê >ÃÊÌÌÃÊi`>]ÊÕ««iÀÊÀiëÀ>ÌÀÞÊviVÌÃ]Ê>`Ê`>ÀÀ i>®Ê>ÀiÊ "/ÊVÌÀ>`V>ÌÃÊ to vaccination. Do not withhold vaccination if a person is taking antibiotics. 2. Does the child have allergies to medications, food, a vaccine component, or latex? [all vaccines] If a person reports they have an allergy to egg, ask if they can eat lightly cooked eggs (e.g., scrambled eggs). If they can, trivalent influenza vaccine (TIV) may be administered. If after eating eggs or egg-containing foods, they have a reaction consisting of only hives, TIV may be given and the person should be observed for at least 30 minutes. If a person experiences a serious systemic or anaphylactic reaction (e.g., hives and either swelling of the lips or tongue, acute respiratory distress, or collapse) after eating eggs, do not administer TIV or live attenuated influenza vaccine (LAIV). It is possible that they may be eligible to be given TIV, but only after they have seen a physician with expertise in the management of allergic conditions. If a person has ana« Þ>ÝÃÊ>vÌiÀÊi>Ì}Ê}i>Ì]Ê`ÊÌÊ>`ÃÌiÀÊ6]Êi>ÃiÃÕ«ÃÀÕLi>Ê,®]Ê ,³Û>ÀVi>Ê,6®]ÊÀÊÛ>ÀVi>ÊÛ>VVi°ÊÊV>ÊÀi>VÌÊÃÊÌÊ>ÊVÌÀ>`V>Ì°Ê For a table of vaccines supplied in vials or syringes that contain latex, go to www.cdc. }ÛÉÛ>VViÃÉ«ÕLÃÉ«LÉ`Ü>`ÃÉ>««i`ViÃÉÉ>ÌiÝÌ>Li°«`v°ÊÀÊ>ÊiÝÌiÃÛiÊ table of vaccine components, see reference 3. 3. Has the child had a serious reaction to a vaccine in the past? [all vaccines] History of anaphylactic reaction (see question 2) to a previous dose of vaccine or vaccine component is a contraindication for subsequent doses (1). HisÌÀÞÊvÊiVi« >«>Ì ÞÊÜÌ ÊÇÊ`>ÞÃÊvÜ}Ê/*É/>*ÊÃÊ>ÊVÌÀ>`V>ÌÊvÀÊ vÕÀÌ iÀÊ`ÃiÃÊvÊ«iÀÌÕÃÃÃVÌ>}ÊÛ>VVi°Ê*ÀiV>ÕÌÃÊÌÊ/>*ÊÌÊ/`>«®ÊVÕ`iÊ Ì iÊvÜ}\Ê>®ÊÃiâÕÀiÊÜÌ ÊÎÊ`>ÞÃÊvÊ>Ê`Ãi]ÊL®Ê«>iÊÀÊ«Êi«Ã`iÊÀÊV>«ÃiÊ within 48 hours of a dose, (c) continuous crying for 3 or more hours within 48 hours of a dose, and (d) fever of 105°F (40°C) within 48 hours of a previous dose. There are other adverse events that might have occurred following vaccination that constitute contraindications or precautions to future doses. Under normal circumstances, vaccines are deferred when a precaution is present. However, situations may arise when the benefit outweighs the risk (e.g., during a community pertussis outbreak). 4. Has the child had a health problem with lung, heart, kidney, or metabolic disease (e.g., diabetes), asthma, or a blood disorder? Is he/she on long-term aspirin therapy? [LAIV] Children with any of the health conditions listed above should not be given the intranasal, live attenuated influenza vaccine (LAIV). These children should be vaccinated with the injectable influenza vaccine. 5. If the child to be vaccinated is between the ages of 2 and 4 years, has a healthcare provider told you that the child had wheezing or asthma in the past 12 months? [LAIV] ÃÌÀÞÊvÊ«ÀÀÊ/`>«ÆÊÓ®ÊyÕiâ>ÊÛ>VViÊ/6ÊÀÊ6®\ÊvÊ-Ê >ÃÊVVÕÀÀi`ÊÜÌ ÊÈÊ weeks of a prior influenza vaccination, vaccinate with TIV if at high risk for severe influenza complications. 8. Does the child have cancer, leukemia, HIV/AIDS, or any other immune system problem? [LAIV, MMR, MMRV, RV, VAR] ÛiÊÛÀÕÃÊÛ>VViÃÊi°}°]Ê,]Ê,6]ÊÛ>ÀVi>]ÊÀÌ>ÛÀÕÃ]Ê>`ÊÌ iÊÌÀ>>Ã>ÊÛi]Ê>Ìtenuated influenza vaccine [LAIV]) are usually contraindicated in immunocompromised V `Ài°ÊÜiÛiÀ]ÊÌ iÀiÊ>ÀiÊiÝVi«ÌðÊÀÊiÝ>«i]Ê,ÊÃÊÀiVi`i`ÊvÀÊ asymptomatic HIV-infected children who do not have evidence of severe immunosuppression. Likewise, varicella vaccine should be considered for HIV-infected children with age-specific CD4+ T-lymphocyte percentage at 15% or greater and may be considered for children age 8 years and older with CD4+ T-lymphocyte counts of greater than or equal to 200 cells/μL. Immunosuppressed children should not receive LAIV. Infants who have been diagnosed with severe combined immunodeficiency - ®Êà Õ`ÊÌÊLiÊ}ÛiÊ>ÊÛiÊÛÀÕÃÊÛ>VVi]ÊVÕ`}ÊÀÌ>ÛÀÕÃÊ,6®ÊÛ>VVi°ÊFor `iÌ>Ã]ÊVÃÕÌÊÌ iÊ *ÊÀiVi`>ÌÃÊ{]Êx]ÊÈ®° 9. In the past 3 months, has the child taken medications that weaken their immune system, such as cortisone, prednisone, other steroids, or anticancer drugs, or had radiation treatments? [LAIV, MMR, MMRV, VAR] ÛiÊÛÀÕÃÊÛ>VViÃÊi°}°]Ê,]Ê,6]ÊÛ>ÀVi>]Ê6®Êà Õ`ÊLiÊ«ÃÌ«i`ÊÕÌÊ>vÌiÀÊ chemotherapy or long-term high-dose steroid therapy has ended. For details and length vÊÌiÊÌÊ«ÃÌ«i]ÊVÃÕÌÊÌ iÊ *ÊÃÌ>ÌiiÌÊ£®°Ê/Êw`ÊëiVwVÊÛ>VV>ÌÊÃV i`ÕiÃÊ for stem cell transplant (bone marrow transplant) patients, see reference 7. LAIV can be given only to healthy non-pregnant individuals age 2–49 years. 10. In the past year, has the child received a transfusion of blood or blood products, or been given immune (gamma) globulin or an antiviral drug? [LAIV, MMR, MMRV, VAR] iÀÌ>ÊÛiÊÛÀÕÃÊÛ>VViÃÊi°}°]Ê6]Ê,]Ê,6]ÊÛ>ÀVi>®Ê>ÞÊii`ÊÌÊLiÊ`iviÀÀi`]Ê `i«i`}ÊÊÃiÛiÀ>ÊÛ>À>LiÃ°Ê ÃÕÌÊÌ iÊÃÌÊVÕÀÀiÌÊ *ÊÀiVi`>ÌÃÊÀÊÌ iÊVÕÀrent Red Book for the most current information on intervals between antiviral drugs, immune globulin or blood product administration and live virus vaccines (1, 2). 11. Is the child/teen pregnant or is there a chance she could become pregnant during the next month? [LAIV, MMR, MMRV, VAR] ÛiÊÛÀÕÃÊÛ>VViÃÊi°}°]Ê,]Ê,6]ÊÛ>ÀVi>]Ê6®Ê>ÀiÊVÌÀ>`V>Ìi`ÊiÊÌ Ê before and during pregnancy because of the theoretical risk of virus transmission to the fetus (1, 6). Sexually active young women who receive a live virus vaccine should be instructed to practice careful contraception for one month following receipt of the vaccine (5, 8). On theoretical grounds, inactivated poliovirus vaccine should not be given during pregnancy; however, it may be given if risk of disease is imminent (e.g., travel to endemic areas) and immediate protection is needed. Use of Td or Tdap is not contraindicated in pregnancy. At the provider’s discretion, either vaccine may be administered during the 2nd or 3rd trimester (9). Children who have had a wheezing episode within the past 12 months should not be given the live attenuated influenza vaccine. Instead, these children should be given the inactivated influenza vaccine. 12. Has the child received vaccinations in the past 4 weeks? 6. If your child is a baby, have you ever been told that he or she has had intussusception? [Rotavirus] If the child was given either live, attenuated influenza vaccine (LAIV) or an injectable ÛiÊÛÀÕÃÊÛ>VViÊi°}°]Ê,]Ê,6]ÊÛ>ÀVi>]ÊÞiÜÊviÛiÀ®ÊÊÌ iÊ«>ÃÌÊ{ÊÜiiÃ]ÊÌ iÞÊ should wait 28 days before receiving another vaccination of this type. Inactivated vaccines may be given at the same time or at any spacing interval. Infants who have a history of intussusception (i.e., the telescoping of one portion of the intestine into another) should not be given rotavirus vaccine. 7. Has the child, a sibling, or a parent had a seizure; has the child had brain or other nervous system problem? [DTaP, Td, Tdap, TIV, LAIV, MMRV] />*Ê>`Ê/`>«Ê>ÀiÊVÌÀ>`V>Ìi`ÊÊV `ÀiÊÜ Ê >ÛiÊ>Ê ÃÌÀÞÊvÊ iVi« >«>Ì ÞÊÜÌ ÊÇÊ`>ÞÃÊvÜ}Ê/*É/>*°ÊÊÕÃÌ>LiÊ«À}ÀiÃÃÛiÊiÕÀ}VÊ«ÀLiÊÃÊ>Ê«ÀiV>ÕÌÊÌÊÌ iÊÕÃiÊvÊ/>*Ê>`Ê/`>«]Ê>`Ê>Ê«À}ÀiÃÃÛiÊiÕÀ}VÊ disorder in a teen is a precaution to the use of Td. For children with stable neurologic disorders (including seizures) unrelated to vaccination, or for children with a family history of seizures, vaccinate as usual (exception: children with a personal or family [i.e., «>ÀiÌÊÀÊÃL}RÊ ÃÌÀÞÊvÊÃiâÕÀiÃÊ}iiÀ>ÞÊà Õ`ÊÌÊLiÊÛ>VV>Ìi`ÊÜÌ Ê,6ÆÊ Ì iÞÊà Õ`ÊÀiViÛiÊÃi«>À>ÌiÊ,Ê>`Ê6,ÊÛ>VViî°ÊÊ ÃÌÀÞÊvÊÕ>>ÀÀjÊÃÞ`ÀiÊ-®ÊÃÊ>ÊVÃ`iÀ>ÌÊÜÌ ÊÌ iÊvÜ}\Ê £®Ê/`É/`>«\ÊvÊ-Ê >ÃÊVVÕÀÀi`ÊÜÌ ÊÈÊÜiiÃÊvÊ>ÊÌiÌ>ÕÃVÌ>}ÊÛ>VViÊ>`Ê decision is made to continue vaccination, give age-appropriate Tdap instead of Td if no [LAIV, MMR, MMRV, VAR, yellow fever] ,iviÀiViÃ\ £°Ê °ÊiiÀ>ÊÀiVi`>ÌÃÊÊÕâ>Ì]Ê>ÌÊÜÜܰV`V°}ÛÉÛ>VViÃÉ«ÕLÃÉ>V«Ã̰ ̰ Ó°Ê *°ÊÊRed Book: Report of the Committee on Infectious Diseases at www.aapredbook.org. Î°Ê />LiÊvÊ6>VViÊ «iÌÃ\ÊÜÜܰV`V°}ÛÉÛ>VViÃÉ«ÕLÃÉ«LÉ`Ü>`ÃÉ>««i`ViÃÉÉÊ Ê excipient-table-2.pdf. {°Ê °Êi>ÃiÃ]ÊÕ«Ã]Ê>`ÊÀÕLi>pÛ>VViÊÕÃiÊ>`ÊÃÌÀ>Ìi}iÃÊvÀÊi>ÌÊvÊi>ÃiÃ]ÊÀÕLi>]Ê>`ÊÊ congenital rubella syndrome and control of mumps. MMWRÊ£nÆÊ{ÇÊ,,n®° x°Ê °Ê*ÀiÛiÌÊvÊÛ>ÀVi>\Ê,iVi`>ÌÃÊvÊÌ iÊ`ÛÃÀÞÊ ÌÌiiÊÊÕâ>ÌÊ*À>VÊ tices. MMWRÊÓääÇÆÊxÈÊ,,{®° È°Ê °Ê*ÀiÛiÌÊ>`Ê ÌÀÊvÊyÕiâ>p,iVi`>ÌÃÊvÊ *Ê>ÌÊÜÜܰV`V°}ÛÉyÕÉ«ÀviÃÊ sionals/vaccination/. Ç°Ê °ÊÝViÀ«ÌÊvÀÊÕ`iiÃÊvÀÊ«ÀiÛiÌ}Ê««ÀÌÕÃÌVÊviVÌÃÊ>}Ê i>Ì«iÌVÊÃÌiÊViÊÊ transplant recipients, MMWR ÓäääÆÊ{Ê,,£ä®]ÊÜÜܰV`V°}ÛÉÛ>VViÃÉ«ÕLÃÉ`Ü>`ÃÉLÚ ÃVÌÀiVð«`v°Ê n°Ê °Ê ÌViÊÌÊÀi>`iÀÃ\Ê,iÛÃi`Ê *ÊÀiVi`>ÌÊvÀÊ>Û`}Ê«Ài}>VÞÊ>vÌiÀÊÀiViÛ}Ê>ÊÊÊ rubella-containing vaccine. MMWR 2001; 50 (49). °ÊÊ °Ê*ÀiÛiÌÊvÊ«iÀÌÕÃÃÃ]ÊÌiÌ>ÕÃ]Ê>`Ê`« Ì iÀ>Ê>}Ê«Ài}>ÌÊ>`Ê«ÃÌ«>ÀÌÕÊÜiÊ>`ÊÊ Ê Ì iÀÊv>ÌÃ\Ê,iVi`>ÌÃÊvÊÌ iÊ *°ÊMMWRÊÓäänÆÊxÇÊ,,{®° Õâ>ÌÊVÌÊ >ÌÊÊUÊÊÌiÊ*{äÈäÊÊUÊÊ«°ÊÓÊÊ 140 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Patient name: Date of birth: (mo.) (yr.) (day) Screening Checklist for Contraindications to Vaccines for Adults For patients: The following questions will help us determine which vaccines you may be given today. If you answer “yes” to any question, it does not necessarily mean you should not be vaccinated. It just means additional questions must be asked. If a question is not clear, please ask your healthcare provider to explain it. Yes No Don’t Know 1. Are you sick today? 2. Do you have allergies to medications, food, a vaccine component, or latex? 3. Have you ever had a serious reaction after receiving a vaccination? 4. Do you have a long-term health problem with heart disease, lung disease, asthma, kidney disease, metabolic disease (e.g., diabetes), anemia, or other blood disorder? 5. Do you have cancer, leukemia, HIV/AIDS, or any other immune system problem? 6. In the past 3 months, have you taken medications that weaken your immune system, such as cortisone, prednisone, other steroids, or anticancer drugs, or have you had radiation treatments? 7. Have you had a seizure or a brain or other nervous system problem? 8. During the past year, have you received a transfusion of blood or blood products, or been given immune (gamma) globulin or an antiviral drug? 9. For women: Are you pregnant or is there a chance you could become pregnant during the next month? 10. Have you received any vaccinations in the past 4 weeks? Form completed by: ___________________________________________ Date:_________________ Form reviewed by: ___________________________________________ Date:_________________ Did you bring your immunization record card with you? yes no It is important for you to have a personal record of your vaccinations. If you don’t have a personal record, ask your healthcare provider to give you one. Keep this record in a safe place and bring it with you every time you seek medical care. Make sure your healthcare provider records all your vaccinations on it. Technical content reviewed by the Centers for Disease Control and Prevention ÊÜÜܰÕâi°À}ÉV>Ì}°`É«{äÈx°«`vÊÊUÊÊÌi*{äÈxÊÊ£äÉ£Ó® IÕâ>ÌÊVÌÊ >ÌÊUÊ£xÇÎÊ-iLÞÊÛi°ÊUÊ-̰Ê*>Õ]Ê Êxx£ä{ÊUÊÈx£®ÊÈ{ÇääÊUÊÜÜܰÕâi°À}ÊUÊÜÜܰÛ>VVivÀ>̰À} July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 141 Information for Health Professionals about the Screening Checklist for Contraindications To Vaccines for Adults Are you interested in knowing why we included a certain question on the screening checklist? If so, read the information below. If you want to find out even more, consult the references listed at the bottom of this page. 1. Are you sick today? [all vaccines] There is no evidence that acute illness reduces vaccine efficacy or increases vaccine adverse events (1). However, as a precaution with moderate or severe acute illness, all vaccines should be delayed until the illness has improved. Mild illnesses (such as upper respiratory infections or diarrhea) are "/ÊVÌÀ>`V>ÌÃÊÌÊÛ>VV>̰ÊDo not withhold vaccination if a person is taking antibiotics. 2. Do you have allergies to medications, food, a vaccine component, or latex? [all vaccines] If a person reports they have an allergy to egg, ask if they can eat lightly cooked eggs (e.g., scrambled eggs). If they can, trivalent influenza vaccine (TIV) may be administered. If after eating eggs or egg-containing foods, they have a reaction consisting of only hives, TIV may be given and the person should be observed for at least 30 minutes. If a person experiences a serious systemic or anaphylactic reaction (e.g., hives and either swelling of the lips or tongue, acute respiratory distress, or collapse) after eating eggs, do not administer TIV or live attenuated influenza vaccine (LAIV). It is possible that they may be eligible to be given TIV, but only after they have seen a physician with expertise in the management of allergic conditions. If a person has anaphylaxis after eating gelatin, do not administer MMR or varicella vaccine. Local reactions are not contraindications. For a table of vaccines supplied in vials or syringes that contain latex, go to www.cdc.gov/vaccines/pubs/ pinkbook/downloads/appendices/B/latex-table.pdf. For an extensive list of vaccine components, see reference 2. 3. Have you ever had a serious reaction after receiving a vaccination? [all vaccines] History of anaphylactic reaction (see question 2) to a previous dose of vaccine or vaccine component is a contraindication for subsequent doses (1). Under normal circumstances, vaccines are deferred when a precaution is present. However, situations may arise when the benefit outweighs the risk (e.g., during a community pertussis outbreak). 4. Do you have a long-term health problem with heart disease, lung disease, asthma, kidney disease, metabolic disease (e.g., diabetes), anemia, or other blood disorder? [LAIV] People with any of these health conditions should not be given the intranasal live attenuated influenza vaccine (LAIV). Instead, they should be vaccinated with the injectable influenza vaccine. 5. Do you have cancer, leukemia, HIV/AIDS, or any other immune system problem? [LAIV, MMR, VAR, ZOS] Live virus vaccines (e.g., LAIV, measles-mumps-rubella [MMR], varicella [VAR], zoster [ZOS]) are usually contraindicated in immunocompromised people. However, there are exceptions. For example, MMR vaccine is recommended and varicella vaccine should be considered for adults with CD4+ T-lymphocyte counts of greater than or equal to 200 cells/μL. Immunosuppressed people should not receive LAIV. For details, consult the ACIP recommendations (3, 4, 5). 6. In the past 3 months, have you taken medications that weaken your immune system, such as cortisone, prednisone, other steroids, or anticancer drugs, or have you had radiation treatments? [LAIV, MMR, VAR, ZOS] Live virus vaccines (e.g., LAIV, MMR, VAR, ZOS) should be postponed until after chemotherapy or long-term high-dose steroid therapy has ended. For details and length of time to postpone, consult the ACIP statement (1, 5). To find specific vaccination schedules for stem cell transplant (bone marrow transplant) patients, see reference 6. LAIV can be given only to healthy nonpregnant people younger than age 50 years. 7. Have you had a seizure or a brain or other nervous system problem? [influenza, Td/Tdap] Tdap is contraindicated in people who have a history of encephalopathy within 7 days following DTP/DTaP given before age 7 years. An unstable progressive neurologic problem is a precaution to the use of Tdap. For people with stable neurologic disorders (including seizures) unrelated to vaccination, or for people with a family history of seizure, vaccinate as usual. A history of Guillain-Barré syndrome (GBS) is a consideration with the following: 1) Td/Tdap: if GBS has occurred within 6 weeks of a tetanus-containing vaccine and decision is made to continue vaccination, give Tdap instead of Td if no history of prior Tdap; 2) Influenza vaccine (TIV/LAIV): if GBS has occurred within 6 weeks of a prior influenza vaccine, vaccinate with TIV if at high risk for severe influenza complications. 8. During the past year, have you received a transfusion of blood or blood products, or been given immune (gamma) globulin or an antiviral drug? [LAIV, MMR, VAR] Certain live virus vaccines (e.g., LAIV, MMR, VAR) may need to be deferred, depending on several variables. Consult the most current ACIP recommendations for current information on intervals between antiviral drugs, immune globulin or blood product administration and live virus vaccines. (1) 9. For women: Are you pregnant or is there a chance you could become pregnant during the next month? [MMR, LAIV, VAR, ZOS] Live virus vaccines (e.g., MMR, VAR, ZOS, LAIV) are contraindicated one month before and during pregnancy because of the theoretical risk of virus transmission to the fetus. Sexually active women in their childbearing years who receive live virus vaccines should be instructed to practice careful contraception for one month following receipt of the vaccine. On theoretical grounds, inactivated poliovirus vaccine should not be given during pregnancy; however, it may be given if risk of disease is imminent and immediate protection is needed (e.g., travel to endemic areas). Use of Td or Tdap is not contraindicated in pregnancy. At the provider’s discretion, either vaccine may be administered during the 2nd or 3rd trimester. (1, 3, 4, 5, 7, 8) 10. Have you received any vaccinations in the past 4 weeks? [LAIV, MMR, VAR, yellow fever] If the person to be vaccinated was given either LAIV or an injectable live virus vaccine (e.g., MMR, VAR, ZOS, yellow fever) in the past 4 weeks, they should wait 28 days before receiving another vaccination of this type. Inactivated vaccines may be given at any spacing interval if they are not administered simultaneously. References: 1. CDC. General recommendations on immunization, at www.cdc.gov/vaccines/pubs/acip-list.htm. 2. Table of Vaccine Components: www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/ excipient-table-2.pdf. 3. CDC. Measles, mumps, and rubella—vaccine use and strategies for elimination of measles, rubella, and congenital rubella syndrome and control of mumps. MMWR 1998; 47 (RR-8). 4. CDC. Prevention of varicella: Recommendations of the Advisory Committee on Immunization Practices. MMWR 2007; 56 (RR-4). 5. CDC. Prevention and control of influenza—recommendations of ACIP, at www.cdc.gov/flu/professionals/vaccination. 6. CDC. Excerpt from Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients, MMWR 2000; 49 (RR-10), www.cdc.gov/vaccines/pubs/downloads/b_hsct-recs.pdf. Ç°Ê °Ê ÌViÊÌÊÀi>`iÀÃ\Ê,iÛÃi`Ê *ÊÀiVi`>ÌÊvÀÊ>Û`}Ê«Ài}>VÞÊ>vÌiÀÊÀiViÛ}Ê>ÊÊÊ rubella-containing vaccine. MMWR 2001; 50 (49). 8. CDC. Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants: Recommendations of the ACIP. MMWR 2008; 57 (RR-4). Õâ>ÌÊVÌÊ >ÌÊÊUÊÊÌiÊ*{äÈxÊÊUÊÊ«°ÊÓ 142 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Instructions for the Use of Vaccine Information Statements Required Use 1. Provide a Vaccine Information Statement (VIS) when a vaccination is given. As required under the National Childhood Vaccine Injury Act (42 U.S.C. §300aa-26), all health care providers in the United States who administer, to any child or adult, any of the following vaccines – diphtheria, tetanus, pertussis, measles, mumps, rubella, polio, hepatitis A, hepatitis B, Haemophilus influenzae type b (Hib), trivalent influenza, pneumococcal conjugate, meningococcal, rotavirus, human papillomavirus (HPV), or varicella (chickenpox) – shall, prior to administration of each dose of the vaccine, provide a copy to keep of the relevant current edition vaccine information materials that have been produced by the Centers for Disease Control and Prevention (CDC): • to the parent or legal representative* of any child to whom the provider intends to administer such vaccine, or • to any adult† to whom the provider intends to administer such vaccine. If there is not a single VIS for a combination vaccine, use the VISs for all component vaccines. VISs should be supplemented with visual presentations or oral explanations as appropriate. *”Legal representative” is defined as a parent or other individual who is qualified under State law to consent to the immunization of a minor child or incompetent adult. †In the case of an incompetent adult, relevant VISs shall be provided to the individual’s legal representative. If the incompetent adult is living in a long-term care facility, all relevant VISs may be provided at the time of admission, or at the time of consent if later than admission, rather than prior to each vaccination. 2. Record information for each VIS provided. Health care providers shall make a notation in each patient’s permanent medical record at the time vaccine information materials are provided, indicating: (1) the edition date of the Vaccine Information Statement distributed, and (2) the date the VIS was provided. This recordkeeping requirement supplements the requirement of 42 U.S.C. §300aa-25 that all health care providers administering these vaccines must record in the patient’s permanent medical record (or in a permanent office log): (3) the name, address and title of the individual who administers the vaccine, (4) the date of administration, and (5) the vaccine manufacturer and lot number of the vaccine used. Applicability of State Law Current VIS Editions Health care providers should consult their legal counsel to determine additional State requirements pertaining to immunization. The Federal requirement to provide the vaccine information materials supplements any applicable State laws. DTaP/DT: 5/17/07 Hib: 12/16/98 Hepatitis A: 10/25/11† Hepatitis B: 2/2/12† HPV (Cervarix): 5/3/11† HPV (Gardasil): 2/22/12† Influenza (inactivated): 7/2/12† Influenza (live): 7/2/12† MMR: 4/20/12† MMRV: 5/21/10† Availability of Copies Copies are available in English and many other languages from CDC’s website at www.cdc.gov/vaccines/pubs/vis. Single camera-ready copies may also be available from State health departments. July 2011, Minnesota Department of Health Meningococcal: 10/14/11† Pneumococcal (PCV13) 4/16/10† Polio: 11/8/11† Rotavirus: 12/6/10† Tdap/Td: 1/24/12† Varicella: 3/13/08† Multi-Vaccine*: 9/18/08† *An optional alternative when two or more routine childhood vaccines (i.e., DTaP, hepatitis B, Hib, pneumococcal, polio, or rotavirus) are administered at the same visit. †Interim Reference 42 U.S.C. §300aa-26 July 3, 2012 Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 143 144 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011 Reliable Sources of Immunization Information :KHUHSDUHQWVDQGSURYLGHUVFDQJRWRÀQGDQVZHUV Websites Vaccines.gov U.S. Department of Health and Human Services (HHS) www.vaccines.gov Consumer-focused immunization website providing easy-to-understand health information to help make informed decisions about immunizations. The content is managed by HHS, but the site is done in collaboration with other government agencies such as CDC and FDA. Vaccine Education Center at Children’s Hospital of Philadelphia www.vaccine.chop.edu Provides facts about each childhood vaccine as well as how vaccines are made, how and why vaccines work, who recommends them, and more. This site notes that it receives no funding from pharmaceutical companies. National Network for Immunization Information (NNii) www.nnii.org Provides current, science-based, extensively reviewed information to health professionals, the media, policy makers, and the public. This site notes that it receives no funding from pharmaceutical companies. Centers for Disease Control and Prevention’s (CDC) National Center for Immunization www.cdc.gov/vaccines Provides immunization information about vaccineSUHYHQWDEOHGLVHDVHVWKHEHQH¿WVRILPPXQL]DWLRQ and the risk of immunization versus the risk of disease, as well as educational materials and resources. Centers for Disease Control and Prevention (CDC) For Parents: Vaccines for Your Children www.cdc.gov/vaccines/parents/index.html 3URYLGHVLPPXQL]DWLRQLQIRUPDWLRQVSHFL¿FDOO\IRU parents. The information can be viewed based on your child’s age. There are also links to parent-friendly immunization schedules and fact sheets about diseases and the vaccines that prevent them. American Academy of Pediatrics Immunization Initiatives www.cispimmunize.org Provides comprehensive immunization information for parents and health professionals. Minnesota Department of Health (MDH) Immunization Program www.health.state.mn.us/immunize Provides information on child, adolescent, adult immunization schedules, policy, laws, and the GLVHDVHVYDFFLQHVSUHYHQW)RUVSHFL¿FLQIRUPDWLRQRQ vaccine safety, click on the vaccine safety link in the left column. Immunization Action Coalition www.immunize.org and www.vaccineinformation.org These sites offer educational pieces for parents and health professionals including many resources on vaccine safety concerns. Publications Clear Answers & Smart Advice About Your Baby’s Shots By Ari Brown, MD, FAAP. This 6-page publication is available for download at www.immunize.org/catg.d/p2068.pdf. Do Vaccines Cause That? A Guide for Evaluating Vaccine Safety Concerns By Martin G. Meyers, MD, and Diego Pineda. I4PH Press. To purchase this book, visit your local bookstore or go to www.immunizationinfo.org/bookstore. Plain Talk About Childhood Immunizations An easy-to-read online immunization booklet for parents, available in English and Spanish from Seattle and King Co. Public Health, WA. Download at www.kingcounty.gov/healthservices/health/communicable/ immunization/plaintalk.aspx or call the Family Health Hotline at 1-800-322-2588. Minnesota Department of Health - Immunization Program (8/12) Page 1 of 2 Available on the web at: www.health.state.mn.us/divs/idepc/immunize/safety/imminfo.html July 2011, Minnesota Department of Health Got Your Shots? Providers Guide - SCREENING & ASSESSING www.health.state.mn.us/immunize 145 Vaccines and Your Child: Separating Fact from Fiction, 2011 %\3DXO2I¿W0'DQG&KDUORWWH0RVHU&ROXPELD University Press. This book answers questions about the science and safety of modern vaccines. To purchase, visit your local bookstore or www.cup.columbia.edu. Parent’s Guide to Childhood Immunizations A 68-page booklet from CDC's National Immunization Program. Available at www.cdc.gov/vaccines/pubs/ parents-guide/default.htm. Call 800-232-4636 for a hard copy or complete the online order form at: www. cdc.gov/vaccines/pubs/default.htm. Vaccine Information Statements (VISs) These fact sheets, produced by the federal Centers for Disease Control and Prevention (CDC) explain the EHQH¿WVDQGULVNVRIYDFFLQHVWRYDFFLQHUHFLSLHQWV their parents, or their legal representatives. Federal law requires that VISs be handed out before certain vaccine doses are given. The VISs are available at www.cdc.gov/vaccines/pubs/vis/default.htm or from your health care provider. Also available in many foreign languages at www.immunize.org/vis. Vaccine Safety for Parents $À\HUIURP&'&¶V1DWLRQDO,PPXQL]DWLRQ3URJUDP available at ZZZFGFJRYYDFFLQHVSXEVÀ\HUV brochures.htm#vacsafe. 7KLVÀ\HUJLYHVHDV\WRXQGHUVWDQGH[SODQDWLRQVRI common vaccine safety concerns. Minnesota Department of Health Immunization Program A toll-free number for health care professionals and FRQVXPHUVZKRKDYH0LQQHVRWDVSHFL¿F immunization questions. 1-800-657-3970 or 651-201-5503. Videos Vaccines: Separating Fact from Fear Vaccines and Your Baby Produced by the Children’s Hospital of Philadelphia. These videos provide answers to parents questions about vaccines. Also available in Spanish. View online at www.chop.edu/service/vaccine-education-center/ order-educational-materials/#viewable-resources or order a copy by calling 215-590-9990 or visiting https://www.chop.edu/vaccine/vec/vec_order.cfm. Vaccine-Preventable Disease – Family Stories This website contains short videos about families who were affected by vaccine-preventable diseases, SURGXFHGE\WKHQRQSUR¿WRUJDQL]DWLRQ3NLGV9LHZ online at www.pkids.org/im_videos.php. Vaccine-Preventable Disease Videos This website contains a variety of short videos about vaccine-preventable disease. www.vaccineinformation.org/video/index.asp Phone Numbers Centers for Disease Control and Prevention (CDC) Immunization Information Hotline A toll-free number for consumers and health professionals who have questions about vaccinepreventable diseases and immunizations. 1-800-CDC-INFO (1-800-232-4636) (Note: This line is for English and Spanish) TTY: 1-800-232-6348 Adapted from the Immunization Action Coalition’s website. Minnesota Department of Health - Immunization Program IC# 141-1450 651-201-5503 or 1-800-657-3970 (8/12) Page 2 of 2 Print version available on the web at: www.health.state.mn.us/divs/idepc/immunize/safety/imminfo.html 146 www.health.state.mn.us/immunize Got Your Shots? Providers Guide - SCREENING & ASSESSING Minnesota Department of Health, July 2011
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