2016 CAREER HANDBOOK The Employer Sourcebook for Scientists I N T RO D U C T I O N Thanks for picking up a copy of the 2016 Career Handbook. Our goal, with this booklet as well as all the career resources from Science, is to bring you useful, relevant information to help you navigate the job search process and manage your development in a way that leads you to a truly rewarding career. To that end, we have teamed up with some great organizations to bring you information about the latest career opportunities in many different fields. The profiles shown here will give you a sense of the types of organizations that are recruiting and the kinds of positions they offer. We’ve also included some articles with some general tips and advice on job searching. In addition to the companies featured in this book, you can search thousands of additional job postings on our website ScienceCareers.org—all for free. T H E T R A N S F E R R A B L E P OS T D O C BY KENDALL POWELL AUGUST 22, 2 014 CONTENTS ARTICLES The Transferrable Postdoc Kendall Powell.................................. 4 2015 Top Employers Kendall Powell.................................. 7 RESOURCES Job Search Essentials.......................15 EMPLOYER PROFILES AAAS Mass Media Fellowships......... 16 AAAS S&T Policy Fellowships........... 18 Abbvie............................................ 20 Biogen............................................ 22 Harvard University, Department of Molecular and Cellular Biology........................ 24 Now more than ever, experts say, postdoctoral fellows need to cultivate a broad base of beyond-the-bench skills and capitalize on transferring them to the next stage of their career to be as competitive as possible. In today’s competitive job market, it is vitally important for postdocs to accumulate skill sets on their CVs right alongside their publications—whether their next career move is research-based or not. Postdocs who repurpose their lab leadership and project management skills into star candidate qualities have an advantage when looking to step into their next position. When an infectious disease fellowship at the Centers for Disease Control and Prevention in Atlanta turned out to be a poor fit for Melissa Ramirez, she moved on to other postdoctoral opportunities where she picked up skills in grant writing, student mentoring, and teaching. Her last stop was as a postdoctoral teaching scholar at North Carolina State University in Raleigh, where she was immersed in teaching and curriculum development for the campus’s undergraduate microbiology students. At each stage of postdoctoral development, Ramirez gained valuable skills that have now successfully translated into a new career as a teaching assistant professor at NC State. Her success was not a given, but came after several years of gathering broad expertise across areas and matching those skills to her interests. Ramirez’ approach should make her postdoctoral colleagues sit up and take note—no matter which direction they take next, it’s a tough job market out there. Almost every sector of the science and technical labor market has tightened since the Great Recession began in 2008. “It’s very hard to find research positions, in general,” says Paula Stephan, professor of economics at Georgia State University in Atlanta and a research associate at the National Bureau of Economic Research. “Postdocs, for the last couple of years, have had particular difficulty because of a soft economy.” Roche.............................................26 MEG BUSCEMA Editor: Allison Pritchard Design: Lisa Baehr Titles and affiliations for authors and for sources quoted were correct at the time of original publication. © 2016 by The American Association for the Advancement of Science. All rights reserved. 1 February 2015. Problem solving, analytical thinking, and understanding how to run proper experiments translate beautifully in today’s companies operating within Internet-based commerce. — Joe Hardy Paula Stephan urges postdocs to periodically step away from their research to make sure they collect transferrable skills, too. Universities in both the United States and Europe are hiring more contract-based faculty or faculty in tenure-track positions that have no salary guarantee and require outside grant funding. Stephan notes that a combination of factors have hit biomedical job candidates especially hard, including the flattening of the U.S. National Institutes of Health budget and the consolidation, downsizing, and off-shoring of jobs among pharmaceutical firms. Some of the largest chemistry labs in the United States, such as DuPont, are also downsizing. “Once we get updated data from the Survey of Earned Doctorates and Survey of Doctorate Recipients, I think we’ll see that industry is hiring fewer Ph.D.s for research positions as well.” Compounding the problem is the expectation gap that exists among the roughly 56% of postdocs who believe they will continue on to tenure-track academic positions and the 21% who actually did in 2012 (scim.ag/XWZwhv). In addition, the definition of a successful academic job candidate has also shifted in the last decade. Beyond stellar research and publication records, faculty candidates must also collaborate across disciplines and the globe, and have a sharp talent for fundraising. 3 Even though writing clearly, presenting complex ideas, and successful completion of projects comes with the postdoc territory, job seekers might need to spell these abilities out for employers. Another invaluable skill postdocs must possess to succeed in almost any later venture is writing clearly and concisely. Doing three paleontology postdocs in France, Berlin, and New York—and writing multiple fellowship applications to fund them—prepared Faysal Bibi for pursuing the large grant he needs to secure a permanent faculty position. Now in a five-year “habilitation” post as an assistant professor of paleontology at the Museum für Naturkunde in Berlin, Bibi says he has the confidence to write a proposal for the €1–2 million grants necessary to sustain a research program. Although this might all seem bleak, Doctorate-holding scientists are highly employable in many arenas. While postdocs tend to put their heads down and toil to collect data, Stephan and others urge them to periodically step away from their research to make sure they collect transferrable skills, too. “Actually many of the skills we need for academic careers are the same for non-academic careers,” says David Bogle, chemical engineer and pro-provost of the Doctoral School at University College London. Strengths in analytical thinking, problem solving, written and oral communication, and collaboration make postdocs universally attractive. “No employer wants somebody that is narrow-minded” or too narrowly focused, say Bogle. PHOTO: BY BRIAN KRAATZ Got skills? When it dawned on Christine Gould that she actually enjoyed the process of writing up her thesis and postdoctoral work, she investigated scientific writing careers. As a medical writer for Health Interactions in San Francisco she prepares manuscripts, slide presentations, and abstracts for biotechnology clients. Careers that employ scientific writing skills include science communications and journalism, medical writing, regulatory affairs, and continuing medical education (or CME). Jeff Sfakianos even found that his manuscript-writing skills were extremely handy when filing patent applications for his therapeutics startup company. Sfakianos, who did a postdoc at Genentech, found that the back-and-forth with patent examiners mirrored the process of peer review. “Writing my own papers was more important than I imagined,” he says. Faysal Bibi A variety of self-assessment resources can help postdocs track their progress. “Young scientists need to periodically sit back and think, what skills do I have? What skills do I need for my project? And what am I lacking?” says Bogle. He recommends the Researcher Development Framework created by Vitae (scim.ag/1lVhLtb), a career development organization based in Cambridge, United Kingdom. The framework covers four domains scientists need to be effective: intellectual knowledge, personal effectiveness, professional standards, and working with others. Similarly, the myIDP website (myIDP.sciencecareers.org) is particularly well-suited to helping biomedical scientists explore careers and set goals for career development. Sibby Anderson Thompkins, director of postdoctoral affairs at University of North Carolina (UNC), Chapel Hill, advises using the National Postdoctoral Association’s Core Competencies document and the checklist at the end of it (scim.ag/1pmZp9l) as a concrete way to discuss professional development and specific skills goals with postdoctoral advisors. A skills frame-shift The core skills that every postdoc needs to transition to a successful academic career are well known. Professorships go to those who exhibit clever experimental design and efficient research project management, who can deliver persuasive scientific arguments, and who are able to write clear, concise, and winning publications and grant proposals. But many postdocs may overlook that those same skills—with a slight tweak in frame-of-mind—make them highly marketable for other positions as well. Anderson Thompkins says postdocs have to shift their own thinking about their acquired skills and how best to present them to potential future employers. “Postdocs are, in fact, mini project managers,” she says, and should describe themselves as such. “Think more broadly—can you manage people, manage time, meet deadlines, and organize? All those skills are really useful in any job. Any job.” Bogle points to another skill that is highly valued in the workplace, but often undervalued by scientists: “The communication of complex ideas in a clear, transparent way. It’s difficult to deliver complex messages quickly.” Joe Hardy adds that problem solving, analytical thinking, and understanding how to run proper experiments translate beautifully in today’s companies operating within Internet-based commerce. “Right now, the way companies think about developing and marketing products is essentially an experimental model,” says Hardy, the vice-president for research and development at Lumosity, a cognitive-training software company based in San Francisco. Web-based and technology firms often take the approach of an A-B test, he says, with different customers exposed to different experiences. Then, companies measure behaviors like clicking links or purchasing in response. Postdocs understand the importance of random assignment of conditions, good experimental controls, and how to process the data coming back. “In this world of the Internet, millions of experiments are happening simultaneously. Experimental design and analysis are big players now,” Hardy notes. 4 Even though writing clearly, presenting complex ideas, and successful completion of projects comes with the postdoc territory, job seekers might need to spell these abilities out for employers. Hardy of Lumosity stresses that if postdocs are transferring outside of their immediate research field, then they must describe in detail (and perhaps in a professionmatched vocabulary) their accomplishments and what useful, relevant skills they have attained. Gould did this by flipping her curriculum vitae on its head. She listed all of her writing experience at the top—including contract editing work, blogging, and courses in science writing—and de-emphasized her research. “I described myself as a medical writer who happens to have eight years of experience in cancer biology.” Later, she was told her resume stood out to the human resources department. Missing from the toolkit Most postdocs make good project managers, shepherding multiple lines of research into a coherent final publication, but they often lack other types of management training. Fiscal, personnel, and time management are critical for careers both inside and outside academia. These skills, along with teaching and business know-how, should top the list of anyone heading out on the job market, but obtaining them requires extra effort. As a senior postdoctoral researcher at Uppsala University in Sweden, Grzegorz Wicher has acquired an impressive list of technical skills from specialized mass spectrometry to microdissection and primary cell culture. But when it came to starting up his own cell culture company, PrimeCell, he took advantage of the Uppsala Innovation Centre, which helps researchers commercialize their ideas. Through the center, he took the three-month Business Lab program to gain some business, marketing, and legal knowledge and to get connected to experts in those areas. He also attends “business pub” meetings every couple of weeks to chat with others starting companies and “exchange knowledge with a beer in your hands.” Chris Blagden, director of CME development and strategy for HealthmattersCME in New York notices another skills gap: while postdocs get loads of practice at bringing projects to an endpoint, they get “very little training in the way of doing it cost-effectively and time-effectively.” These are key for CME projects—and for many other client- or product-based projects—that must come in on time and under budget. Postdocs who have managed their own research budget or met tight deadlines may have a leg up. 5 PHOTO: COURTESY OF GRZEGORZ WICHE Grzegorz Wicher attends “business pub” meetings every couple of weeks to chat with others starting companies. T O P F I R M S P R I O R I T IZE T R A N S F O R M AT I V E T EC H N O LO G I E S , PAT I E N T S Considerable skills gaps can exist even for postdocs remaining in academia. The leap from postdoc to lab head comes with considerable shifts in focus and responsibilities—teaching, lab management, dealing with interpersonal conflicts, and a penchant for fundraising (scim.ag/1mCSOTf)—which don’t necessarily come naturally. Academic career development programs, like the popular Preparing for Academic Practice at Oxford University in the United Kingdom, can pave the way for postdocs moving toward tenure-track posts. Ramirez’ teaching scholars program at North Carolina State University provides a foundation for transitioning to teaching faculty positions. With other fellows, she helped teach, organize, and administer the courses and answered student questions. Postdocs can also explore teaching careers through programs such as the American Society for Microbiology’s Teaching Fellows Program, a five-month online development course. Ramirez says her past research career greatly influences her teaching. She was already skilled at distilling down her research to a few sentences to grab the attention of scientists outside her field. “It’s the same thing with students—you have a few minutes to capture their attention in a lecture or you’ve lost them for 50 minutes.” Running a successful marketing campaign Regardless of whether postdocs transfer skills to a permanent professorship or to another field entirely, they must think broadly about how to market themselves when the time comes. Much like a presidential bid, running a successful selfmarketing campaign requires starting years ahead. Anderson Thompkins says that postdocs who come to the UNC office early realize they must have a clear sense of their end goal to maximize their postdoctoral time. The most successful postdocs, she says, consider different options, having multiple “plan Bs” and do not bank on one particular career path. Bogle suggests that trainees ponder career choices at two special times: research highs and research lows. “Take a break and look around. Go to the pub with friends and talk about it. Explore, get out there and find out what’s on offer. Make all the connections you can and make use of all the external contacts you can.” “Take a break and look around. Go to the pub with friends and talk about it. Explore, get out there and find out what’s on offer.” — David Bogle Young scientists have things backwards if they research intensely for 10–12 hours per day and then only spend 15 minutes on a job search, says Hardy. “You should spend significant amounts of time investigating, networking, and understanding what people like you have gone on to do.” Although self-promotion doesn’t always come naturally to scientists, postdocs need to think strategically about how best to position themselves in the research enterprise. In his various postdoc posts, Bibi soaked up cutting-edge techniques, such as evolutionary meta-analysis and genomics, and made valuable personal connections. “What paid off is that I liked to be a bit of the odd one out, surrounded by people who worked on different things or in different [geologic] time periods.” This way, he gained both innovative technical skills and expanded his network well beyond his subfield. As an academic job candidate, he says, “this is something I think I can sell much better than simply saying that I study fossil antelopes.” Bibi has landed on the exact right word: “sell.” Job searching in today’s market is fundamentally about selling yourself, your ideas, and your skills and convincing a potential employer of your value. Luckily, that’s one skill many postdocs have already unwittingly mastered. After all, how many times have you given a seminar and successfully persuaded the crowd to believe you and your data? 6 BY KENDALL POWELL O CTOBER 3 0, 2 015 The biotechnology and pharmaceutical sectors have emerged from the global recession to find technological breakthroughs driving renewed enthusiasm and risk-taking at companies. The firms landing at the top of the 2015 Science Careers Top Employers Survey have harnessed these innovative sparks and created workplaces that recruit the best and brightest scientific minds. Their researchers are largely given free rein to develop the next big thing in green agricultural biotechnology (agbiotech) or cancer treatment. Real-world results from such breakthrough innovations inspire the next generation of industry researchers as they ride the crest of a new wave of biological advances. These top employers ensure that their scientists surf that wave with agility, passion for what they do, and creativity to arrive at technologies that will transform lives. It sounds like an old game show. The buzzword is “transformative technologies.” But it’s truly more than a buzzword. A palpable excitement travels through both boardrooms and scientific conferences following breakthroughs in immunotherapy, messenger RNA (mRNA) therapies, or microbiome mining. Many companies have made a strategic migration away from the tried-and-true (but also too long and costly) pathways of drug discovery toward novel approaches that promise unprecedented speed and precision. That excitement is one reason that scores in this year’s Science Careers Top Employers Survey were higher in general— more so than in the last four years. A better economic outlook, with venture capital money flowing into the biotechnology and biopharmaceutical sectors more freely, doesn’t hurt either. The scores reflect a breath of fresh air from scientific advances that translate into not merely incremental advances, but rather transformative new medicines or solutions. This year like all others, scientists want to work at companies that keep innovation front and center, and the top 20 employers in 2015 include those biotechnology and pharmaceutical firms on the leading edge of these advances. Three new players arrive on the top 10 leaderboard this year, focused on making the world a greener place, developing therapies for unique patient populations, or creating a revolutionary technology platform—all first-time survey participants. Each firm is relatively small, but with growing global reach: Novozymes (#1) has 6,000 employees, Alexion Pharmaceuticals (#5) has 2,800 employees, and Moderna Therapeutics (#7) has more than 250 employees. We’re a mid-sized company and that actually matters,” says Peder Holk Nielsen, chief executive officer of top-ranked Novozymes. “It’s possible to maintain a family-like environment and still operate globally.” Novozymes boasts of an uber-friendly workplace (rooted in the company’s Danish heritage) and a culture that is science-centric. Twenty-one percent of the company’s employees are working in labs, and the company touts the fact that 14% of its total revenue is reinvested into R&D annually. “Zymers,” as company employees are called, are also given high levels of responsibility from day one. “It means that young scientists will be charged with significant programs without a lot of managerial follow-up,” says Nielsen. “We trust people to do their best—it’s a flat organization where everyone can talk to everyone else—and you are expected to have an opinion and voice it.” Politely, of course. All the top employers included here exhibit these notions of open communication, flat hierarchies, and environments that encourage scientists to challenge conventional wisdom. As the highest-revenue pharmaceutical company to make the top 10, Roche (#8) had 17,566 R&D employees and invested $9 billion in R&D in 2014. Bristol-Myers Squibb (BMS), which returns to the survey at #20 after an eight-year absence, has a corporate stance of taking big risks while following solid science. Biocon (#13), based in Bengaluru, India, returns to the list this year as the only firm 7 headquartered in Asia. And Celgene Corporation (moving up to #12 this year after placing #17 in 2013 and #15 in 2014) leapt ahead of other mid-sized biopharma peers, Biogen (#18) and Gilead (#19). These successful workplaces keep creativity and innovation at the heart of operations—giving employees the responsibility and control over developing projects and their own careers. These firms are filled with motivated employees because real-life examples of their work’s impact on the world are woven into their cultures. And though recruiting and retaining a highly skilled work force is cited as a major challenge for the industry, these companies excel at attracting and keeping top talent. Benefits, both official and fun perks, keep employees’ eyes on the prize— developing bold ideas into the next transformative application. “We are not looking for therapies that give incremental benefits,” says Martin Mackay, head of research and development for Cheshire, Connecticut-based Alexion. He explains that a focus on rare and ultrarare diseases grew organically out of the company’s mission to find transformative therapies for devastating diseases. One such condition, hypophosphatasia (HPP), can be fatal in severe cases in newborns who lack a properly formed ribcage needed for breathing. This year, Alexion anticipates U.S. approval for Strensiq, an enzyme replacement therapy for HPP. FOCUS ON CAREERS Mackay ticks off the impressive results that patients and their families have experienced: “Babies breathing on their own, Produced by the Science/AAAS Custom Publishing Office children growing at normal rates, even playing sports—this is the daily drive we have at Alexion. ANNUAL TOP EMPLOYERS SURVEY Top twenty employers 2015 2014 Rank Rank 1 2 3 4 5 6 – 1 2 4 – 3 7 – 8 8 9 6 10 11 12 13 14 15 16 17 18 19 20 7 5 15 – 12 13 16 20 10 – – The 20 companies with the best reputations as employers and the top three driving characteristics for each company, according to respondents in the 2015 survey undertaken for the Science/AAAS Custom Publishing Office. The companies without a 2014 rank did not receive enough mentions to qualify or did not receive a high enough ranking during the 2014 survey. Employer (Global headquarters) Innovative leader in the industry Novozymes (Bagsvaerd, Denmark) Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) Novo Nordisk (Bagsvaerd, Denmark) Vertex Pharmaceuticals (Boston, MA) Alexion Pharmaceuticals (Cheshire, CT) Genentech (South San Francisco, CA) Moderna Therapeutics (Cambridge, MA) ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ Roche—excluding Genentech (Basel, Switzerland) Monsanto Company (Creve Coeur, MO) AbbVie (North Chicago, IL) Eli Lilly and Company (Indianapolis, IN) Celgene Corporation (Summit, NJ) Biocon (Bangalore, India) Abbott (Abbott Park, IL) Boehringer Ingelheim (Ingelheim, Germany) Bayer (Leverkusen, Germany) Merck KGaA (Darmstadt, Germany) Biogen (Cambridge, MA) Gilead (Foster City, CA) Bristol-Myers Squibb (New York, NY) Mackay ticks off the impressive results that patients and their families have experienced: “Babies breathing on their own, children growing at normal rates, even playing sports—this is the ✓ ✓ Treats employees with respect ✓ ✓ Has loyal employees ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ 8 ✓ ✓ Work culture values aligned ✓ ✓ ✓ ✓ Is socially responsible ✓ ✓ ✓ 2015 Top employers survey methodology Science Careers conducted its annual web-based survey of individuals familiar with pharmaceutical and biotech employers to determine the best employers in the field. This survey was conducted from March 18 to April 24, 2015. Roughly 41,000 individuals from the AAAS database, as well as former survey participants, were invited via e-mail messages to take this survey. Individuals working in human resources at biotech and pharma companies (Science Careers sales database) were also contacted by e-mail and asked to promote the survey within their organization. In all, 5,700 surveys were submitted, which served as the basis for the analysis. The top 20 companies were selected using a statistical process that calculates a unique ranking score for each company rated. Only companies that were rated by 35 or more respondents were eligible to become part of the top 20 best employers. What makes top employers shine? Each year, Science Careers commissions a survey to identify the top employers in the biotechnology and pharmaceutical industry and to determine the characteristics that best describe a top employer. This year, the results are based on 5,700 responses to a web-based survey deployed by e-mail (see Survey Methodology). The vast majority of respondents are scientists working in areas of basic or applied research and development (see Survey Demographics box). Of the one-fifth of respondents likely to seek a new job in the next year, more than half will do so to seek career advancement or new opportunities. Human resources officers at top firms are not surprised—they say employees place a higher emphasis on career development than total compensation. In selecting the best companies, respondents yet again chose “innovative leader” as the top-driving characteristic. A top employer is also defined as an organization that “treats employees with respect,” “has loyal employees,” “is socially responsible,” and has a “work culture aligned” with employees’ values (see Driving Characteristics table). The 2015 survey included a way for respondents to rank the biggest advantages to working in the biopharma industry. Workers voted “innovation” solidly as #1, followed by “working with smart colleagues” and “excellent compensation and Produced by the Science/AAAS Custom Publishing Office benefits” as a close #2 and #3, respectively. Interestingly, workers ranked having the funding and resources for research ANNUAL TOP EMPLOYERS SURVEY projects as a more distant #4. FOCUS ON CAREERS ✓ Demographics ✓ Gender: 54% Male, 42% Female, 4% No response Experience: ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ with respect,” “has loyal employees,” “is socially responsible,” and has a “work culture aligned” with employees’ values (see Driving Characteristics table, page TK). 65% have 10 or more years work experience ✓ Highest degree earned: 37% Doctorate, 32% Master’s, 24% Bachelor’s, 7% Other Company type: 34% Pharma, 34% Biotech, 24% Biopharma, 2% University, 6% Other; More than 9 out of 10 work in private industry ✓ ✓ ✓ ✓ Nature of work: 36% Development, 28% Applied Research, 20% Basic Research, 10% Administration/Executive, 14% QA/QC/Regulatory Affairs, 8% Production, 11% Other (respondents were able to choose more than one response) Geography: 57% from North America, 27% from Europe, 11% from Asia/Pacific Rim, 5% from rest of world The firm dropped discovery and development in the areas of diabetes, virology, and neuroscience in favor of a research focus 9 for position on the immunotherapy wave, with BMS holding the Companies meeting those challenges adeptly and leader’s position. fulfilling advantages BMS’s twothose monoclonal antibodyinclude productsRegeneron both act on T-cell checkpoints, mechanisms that normally act to shut down an imPharmaceuticals, Incorporated (#2), Novo Nordisk mune response once the job is finished. Some cancers have also (#3),ways Vertex Pharmaceuticals (#4), Genentech (a T found to trigger these checkpoints to effectively shut off member of the Roche group) (#6), Monsanto Company cells and hide from the immune system. By masking checkpoint receptors, Yervoy and Opdivo number circulating, (#9), and AbbVie (#10),expand whichthe round outof the top 10 tumor-recognizing T cells. employers (see chart for full top 20 list). “The consequence is that the T lymphocytes are back at work and our natural defense system does a very good job” attacking tumors, says Namouni. Both drugs are approved for treating The comeback company metastatic melanoma, and Opdivo is also approved for squamous lung cancer. Namouni says immuno-oncology field exploded BMS’s comeback as athetop employer after last after BMS showed that the immune-activating approach not only appearing on the in 2007 is no mere coincidence. worked, but worked on list notoriously stubborn cancers. Theseperiod amazingaligns successes made believers ofmakeover, investors That withhave a company-wide and researchers alike, with a flood of companies adding cancer during which BMS made a series of decisions to immunotherapy components to their portfolios. Both Celgene turn around a firmstaked that out hadterritory become one of the least and Roche have firmly on the immunotherapy stage already. in the industry. profitable Roche has four biologic cancer immunotherapy molecules in clinical trials that could work in powerful combinations with each other or with current drugs, says William Pao, global head of oncology discovery in Basel. Those candidates include antibodies that would activate and arm more T cells and bispecific, engineered antibodies that physically bring T cells to the tumor cells they are armed to kill. Another engineered antibody would tag tumor cells with an immunocytokine that preferentially activates killer T cells. The firm dropped discovery and development in the areas of diabetes, virology, and neuroscience in favor of a research focus on oncology, heart failure, genetically defined diseases, immunoscience, and fibrotic diseases. In 2009, BMS took a big risk jumping into the immunotherapy field by acquiring the company Medarex, which brought with it Yervoy, a member of a new class of cancer drugs. In 2011, Yervoy became a breakthrough treatment for metastatic melanoma, and BMS quickly followed that success with another immuno-oncology drug, Opdivo. By June 2015, the transformation was largely complete, with BMS renewing its focus on the abovementioned areas and also on immuno-oncology, where it held a huge lead over the competition. The company that emerged on the other side was slimmer, shedding the weight of a large, too-diversified drug company to become a biopharmaceutical firm focused on specialty therapies for high medical needs. “It completely changed the atmosphere. It’s changing the outcomes for these terrifying diseases,” says Fouad Namouni, head of development for Yervoy and Opdivo at BMS’s headquarters in Princeton, New Jersey. “We are walking the talk, trying to help save lives.” As such, he says the makeover was not only the right business decision, but was highly motivating for BMS researchers, too. BMS had 7,300 R&D employees, invested $4.5 billion in R&D in 2014, and expects to open a new R&D campus in Cambridge, Massachusetts in 2018. Namouni credits trailblazing and bold leadership for BMS’s success in immuno-oncology. “No matter what the science was telling us, we followed it and applied it, even during times when people thought it was heresy.” Riding the immunotherapy wave And people did think so. Although the idea of immunotherapy—activating or boosting the body’s natural defenses to fight diseases better—has been around for decades, the molecular keys to unleash the immune system without doing more damage than good have long remained mysterious. But in the last decade, the field has made a tsunami of progress. Now, pharmaceutical manufacturers are jostling for position on the immunotherapy wave, with BMS holding the leader’s position. BMS’s two monoclonal antibody products both act on T-cell checkpoints, mechanisms that normally act to shut down an immune response once the job is finished. Some cancers have also found ways to trigger these checkpoints to effectively shut off T cells and hide from the immune system. By masking checkpoint receptors, Yervoy and Opdivo expand the number of circulating, tumor-recognizing T cells. “We are walking the talk, trying to help save lives.” — Fouad Namouni “The consequence is that the T lymphocytes are back at work and our natural defense system does a very good job” attacking tumors, says Namouni. Both drugs are approved for treating metastatic melanoma, and Opdivo is also approved for squamous lung cancer. Namouni says the immuno-oncology field exploded after BMS showed that the immune-activating approach not only worked, but worked on notoriously stubborn cancers. These amazing successes have made believers of investors and researchers alike, with a flood of companies adding cancer immunotherapy components to their portfolios. Both Celgene and Roche have firmly staked out territory on the immunotherapy stage already. Roche has four biologic cancer immunotherapy molecules in clinical trials that could work in powerful combinations with each other or with current drugs, says William Pao, global head of oncology discovery in Basel. Those candidates include antibodies that would activate and arm more T cells and bispecific, engineered antibodies that physically bring T cells to the tumor cells they are armed to kill. Another engineered antibody would tag tumor cells with an immunocytokine that preferentially activates killer T cells. 10 Much like BMS, Celgene also made a big gamble about a decade ago when it developed a class of immune-modulating drugs that included the infamous teratogen thalidomide. These immunomodulatory drug (IMiD) compounds, including Revlimid, were successful at targeting multiple myeloma and lymphoma. They work by boosting the degradation of key factors for white blood cell production. Transformative biotechnologies Other top employer innovations harbor the potential to change lives as well. Transformative biotechnologies at Moderna and Novozymes are changing the way scientists approach both medicine and agriculture. Novozymes is a relative newcomer to the biopharmaceutical realm, having split from Novo Nordisk in 2000. Headquartered in Bagsvaerd, Denmark, the enzyme-based company makes industrial, biofuel, agricultural, and medical products. Some of Novozymes’ latest technological pushes rely on mining the microbiome to find powerful new enzymes or activities. Chief Scientific Officer Per Falholt says that the enzymes discovered to date are only the tip of the iceberg. “In the past, we were restricted to microbes we could grow in the lab, but metagenomics gets around that,” he says. Teaming up with fellow top employer Monsanto, Novozymes’ scientists are developing microbial seed treatments that will yield more corn and soybeans, ideally with less chemical fertilizers, pesticides, or water. These microbes might increase crop yields by releasing more phosphate or nitrogen from the soil. Nathan Cude works in Novozymes’ agbiotech division in Durham, North Carolina in the microbial discovery group, which isolates and identifies thousands of microbes collected from soil samples around the United States. After characterizing the bugs genetically and biochemically, and assessing safety risks, the group nominates promising candidates to Monsanto for testing inthe500,000 annual field trials Produced by Science/AAAS Custom Publishing Office of everyANNUAL imaginable soil and weather TOP EMPLOYERS SURVEY scenario. FOCUS ON CAREERS Driving characteristics of top employers 2015: 2014: 1. Innovative leader in the industry 1. Innovative leader in the industry 2. Treats employees with respect 2. Treats employees with respect 3. Loyal employees 3. Loyal employees 4. Socially responsible 4. Socially responsible 5. Work culture values aligned 5. Work culture values aligned 6. Makes changes needed Driving characteristics are listed in descending order of impact on overall employer rankings. The colored backgrounds indicate the characteristics in common for the two years. aregenetics extremely and genuinely patient-centric,” of molecular to work, but, this case, as an entirely new Moderna’s mRNAgenetics therapeutics alsoin put the power of molecular to work, but, in this case,says asMackay. an entirely new That “patientricity” can be seen in town-hall meetings where drug modality. Formed in 2011 and based in Cambridge, Massadrug modality. Formed in 2011 and based in Cambridge, Massachusetts, Moderna is the newest top employer on the patients share their disease and treatment experiences. After chusetts, Moderna is the newest top employer on the block. The block. The company’s mRNA drugs incorporate occurring analogs that evade the body’s visits from Alexion’s nucleotide youngest patients, Mackay says he often company’s modifiedmodified mRNA drugs incorporate naturally occurring naturally sees employees “walking on air, going back to their lab benches analogs that evade the body’s efficient efficientnucleotide dispatch of foreign, introduced RNA. dispatch of foreign, introduced RNA. or offices knowing that they could have a real impact on children.” Theinnovation urgency to find treatments for life-threatening conditions Matt Stanton, Moderna’s head chemistry, says thethe compaMatt Stanton, Moderna’s head ofofchemistry, says company’s can use exogenous, synthesized mRNA translates into a company culture that is fast-paced, hardworking, ny’s innovation can use exogenous, synthesized mRNA to create to create protein of interest targeted cell types orare tissues. are obvious no-brainer advantages that and“There entrepreneurial in spirit, says Clare Carmichael, chiefto human anyany protein of interest in targetedincell types or tissues. “There resources officer for Alexion. obvious advantages to that approach” in cost, speed, approach” in no-brainer cost, speed, and efficacy, he says. and efficacy, he says. Similarly, Novozymes’ Nielsen says that young employees are not driven by the their paychecks, but rather personal Chief Executive Officer Stéphane Bancel adds: ModernaModerna Chief Executive Officer Stéphane Bancel adds: “mRNA drugs cansize doofthings for patients thatbysmall molecules development and making an impact. “People want to tell their “mRNA drugs can do things for patients that small molecules and huge antibodies cannot do.” Among other feats, the technology has the potential to serve up gene therapy without kids when they pick them up from kindergarten, ‘I did something and huge antibodies cannot do.” Among other feats, the genetictechnology tinkering, and it can deliver without themakes messiness of acell-based therapies. Stanton says today that this world better place to live,’” he says. has the potential to serveregenerative up gene therapymedicine without company’s “makeamore with less” plays out across tinkering,could and it can regenerative medicine without that thegenetic technology alsodeliver tackle “undruggable” targets, forThe example bytagline replacing missing intracellular protein or its science, from detergent enzymes that save energy and water the messiness of cell-based therapies. Stanton says that the disrupting a protein-protein interaction. to technology for converting waste biomass into biofuels. It even technology could also tackle “undruggable” targets, for example by replacing a missing intracellular protein or disrupting a proteinprotein interaction. Innovation has remained the survey’s top driver for 12 years running. It’s not surprising that scientists want employers who give them the space and freedom for the creativity needed to find to trickles into travel planning, with employee reminders about car- footprints. 1bon 1That emphasis on sustainability appealed to scientist Leah Blasiak when she transitioned from academia to her current post in the agbiotech division at Novozymes. “What I do Innovation has remained the survey’s top driver for 12 years running. It’s not surprising that scientists want employers who give them the space and freedom for the creativity needed to find to fresh solutions. Celgene scientist Patrick Hagner develops next-generation IMiD therapies, including drug candidate CC122. When asked what he likes best about working there, he replies, “The nerd in me says innovative science is what defines this company.” But he also mentions a particular 20-year-old lymphoma patient whose cancer had failed to respond to multiple chemotherapies. After enrolling in a clinical trial for CC122, the patient experienced a remission. “To have actually helped somebody live longer—that’s one of the most enjoyable qualities of working here.” Putting patients, planet first Hagner is not alone in being motivated by making such a tangible difference. Most top employers scored highly for being responsible corporate citizens and for having corporate values that aligned with their employees’ own beliefs. Many have sustainability initiatives like buildings powered by wind and recycled water (Celgene), partnering with local Habitat for Humanity projects (Moderna), or volunteering at patient events like the National Veterans Wheelchair Games (BMS). Last year, Celgene employees raised funds alongside the Multiple Myeloma Research Foundation in the Empire State Building Run-Up, racing up all 86 flights of stairs in less than 15 minutes. Recruiting and retaining top talent Recruiting talented young scientists like Blasiak and keeping them on board for the long haul was cited by this year’s survey respondents as one of the industry’s biggest challenges. Top firms say they have not-so-secret weapons for attracting the best scientists and keeping them stimulated. “Novozymes’ success is determined by the passion and energy that Zymers bring to work each morning,” says Nielsen. He says his firm is often a first choice for scientists in Denmark, Sweden, and Germany who are familiar with it, but recruiting in the United States or Asia is more difficult. Falholt says that Novozymes looks for scientists who “burn high,” chewing on problems until a solution comes to them, whether during work hours or not. Likewise, every Moderna employee is given an iPhone and iPad connected to the Produced by the Science/AAAS Custom Publishing Office company cloud, so if genius strikes while an employee reads her Sunday paper, it can be captured instantly. FOCUS ON CAREERS ANNUAL TOP EMPLOYERS SURVEY Comparison of top ten’s top characteristics That “patientricity” can be seen in town-hall meetings where patients share their disease and treatment experiences. After visits from Alexion’s youngest patients, Mackay says he often sees employees “walking on air, going back to their lab benches or offices knowing that they could have a real impact on children.” The urgency to find treatments for life-threatening conditions translates into a company culture that is fast-paced, hardworking, and entrepreneurial in spirit, says Clare Carmichael, chief human resources officer for Alexion. Similarly, Novozymes’ Nielsen says that young employees are not driven by the size of their paychecks, but rather by personal development and making an impact. “People want to tell their kids when they pick them up from kindergarten, ‘I did something today that makes this world a better place to live,” he says. 90 Roche— excluding Genentech AbbVie “People want to tell their kids when they pick them up from kindergarten, ‘I did something today that makes this world a better place to live,” — Peder Holk Nielsen That emphasis on sustainability appealed to scientist Leah Blasiak when she transitioned from academia to her current post in the agbiotech division at Novozymes. “What I do matters, and I am much closer to the direct application of my research,” she says. Novozymes Vertex • Innovative leader in the industry (x-axis), • Treats employees with respect (y-axis), 80 Genentech The company’s tagline “make more with less” plays out across its science, from detergent enzymes that save energy and water to technology for converting waste biomass into biofuels. It even trickles into travel planning, with employee reminders about carbon footprints. 12 RESPECT Two firms, however, stand out in the crowd for placing patients’ needs (Alexion) and sustainability (Novozymes) squarely at the center of their business model. “In this industry, everyone is trying to come up with important, good medicines, but at Alexion, we are extremely and genuinely patient-centric,” says Mackay. Novo Regeneron Nordisk Width of bubble = LOYAL EMPLOYEES 100 70 Comparison of the top 10 companies on the basis of the top three drivers (scored out of 100): Monsanto 75 80 85 90 Moderna Therapeutics 95 • Has loyal employees (bubble width). Alexion 100 INNOVATIVE senior vice president for human resources. “I look for it in every who cares?” he dismisses. Providing an environment where interviewee, because the one constant is that Moderna is employees can dream up new ideas and carry them out is more Manychanging,” top employers employees who arewith “learning whoideation can wear he says. are growing rapidly, and so they look forimportant. “It is the speed which weagile,” move from to When hiring at Roche, Pao says that personality is equally as execution that makes Moderna special.” multiple, shifting hats, and who excel at cross-functional or even cross-company collaboration. Job candidates must important as a deep understanding of disease biology and an showappreciation the capacity for development. managing uncertainty, change, ambiguity in a fast-moving company, says Moderna’s Unbridled enthusiasm of drug “We look for a team player and even That for buzzitfor done permeates all top employer can fit into a matrix echoing other top “I look Stevewho Harbin, senior viceenvironment,” president he forsays, human resources. ingetting everythings interviewee, because the one constant is companies and shines through in this year’s historically positive employers as well. That means someone who can ferry his ideas that Moderna is changing,” he says. overall survey scores. Even though the global economic outlook and data between all the various layers of a drug development ticked upward, attribute theof survey’s optimistarget discovery to that chemistry to preclinical tools Whenprogram—from hiring at Roche, Pao says personality is equally ashas important as aindustry deep leaders understanding disease biology tic attitudes to scientific excitement rather than financial security. and testing, clinical development, and beyond. and an appreciation of drug development. “We look for a team“It’s player fit into asitting matrix environment,” uniquewho to becan at a company on top of discoveries he says, Respect loyalty as well. That means someone who that are actually the and standard care in cancer,” saysvarious echoing otherbegets top employers can ferrychanging his ideas dataof between all the It’s an old maxim of business: People leave employers because Carl Decicco, head of discovery at BMS. Four of the company’s layersofof a drug development program—from target discovery to chemistry to preclinical tools and testing, bad managers. This year, the second-most important driver of immuno-oncology drug trials had to be stopped due to the clinical ethitop employers was respecting employees, followed closely by cal need to offer the more effective experimental treatment to development, and beyond. having loyal employees. Workers at the best companies say that the other arm of patients receiving standard care. “BMS is willing respect, which can take many forms, begets loyalty. At Novoto take risks that are backed by good scientific data,” he says. zymes, employee turnover is low—just 8.5% worldwide in 2014— “We’re getting a lot of things right and people are finding it an reflecting a very low proportion of heavy-handed managers, says exciting place to work.” Michael Almer, vice president of human resources. Not resting on laurels inspires Celgene’s employees to always The company also puts a Scandinavian twist on trust—giving strive for the next level of success, says Chief Financial Officer employees a hefty dose of responsibility upfront. Cude recalls bePeter Kellogg. “We try to keep the money focused on the science ing handed that mantle on day one, starting in an empty lab with and innovation.” He says employees appreciate long-range plan12 others at the new agbiotech facility. “We still had these goals ning and vision that allows companies to ride out shifting financial and timelines dictated by the growing season to meet,” he says. trade winds. “There’s something to be said for persistence and “I was put into the deep end, but it was a really great learning and never feeling like we are a successful company.” networking experience.” Above all else, employees rank innovations that allow them to Smaller tokens of employee appreciation don’t hurt either. Commake a positive, real impact in the world—not compensation, 13 panies have brought in “jeans every day” dress codes (Alexion), retirement benefits, or career advancement—as the biggest refree ice cream trucks (Novozymes), and an electric car for zipping ward of working in biotech and pharmaceuticals. Blasiak refers between campuses (Moderna). to an oft-repeated motto at Novozymes about having a “triple” Job Search Essentials Questions Respect begets loyalty It’s an old maxim of business: People leave employers because of bad managers. This year, the second-most important driver of top employers was respecting employees, followed closely by having loyal employees. Workers at the best companies say that respect, which can take many forms, begets loyalty. At Novozymes, employee turnover is low— just 8.5% worldwide in 2014—reflecting a very low proportion of heavy-handed managers, says Michael Almer, vice president of human resources. The company also puts a Scandinavian twist on trust—giving employees a hefty dose of responsibility upfront. Cude recalls being handed that mantle on day one, starting in an empty lab with 12 others at the new agbiotech facility. “We still had these goals and timelines dictated by the growing season to meet,” he says. “I was put into the deep end, but it was a really great learning and networking experience.” Smaller tokens of employee appreciation don’t hurt either. Companies have brought in “jeans every day” dress codes (Alexion), free ice cream trucks (Novozymes), and an electric car for zipping between campuses (Moderna). More serious benefits make high-performance employees’ lives a little less stressful. Alexion provides paid caregiver leave to spend time with a terminally ill loved one and coaches for families navigating college applications. Celgene places a hefty emphasis on employee wellness, employing a nurse practitioner to treat employees on-site and providing hot, healthy to-go dinners from its cafeteria and local, farm-fresh produce for employees to buy on their way home. Moderna operates on the cantina model, serving a free catered lunch so employees can discuss matters over the daily meal. But Harbin pooh-poohs the idea that perks like foosball tables will reel in or retain employees. “So Moderna provides free lunch, who cares?” he dismisses. Providing an environment where employees can dream up new ideas and carry them out is more important. “It is the speed with which we move from ideation to execution that makes Moderna special.” Unbridled enthusiasm That buzz for getting things done permeates all top employer companies and shines through in this year’s historically positive overall survey scores. Even though the global economic outlook has ticked upward, industry leaders attribute the survey’s optimistic attitudes to scientific excitement rather than financial security. “It’s unique to be at a company sitting on top of discoveries that are actually changing the standard of care in cancer,” says Carl Decicco, head of discovery at BMS. Four of the company’s immuno-oncology drug trials had to be stopped due to the ethical need to offer the more effective experimental treatment to the other arm of patients receiving standard care. “BMS is willing to take risks that are backed by good scientific data,” he says. “We’re getting a lot of things right and people are finding it an exciting place to work.” Not resting on laurels inspires Celgene’s employees to always strive for the next level of success, says Chief Financial Officer Peter Kellogg. “We try to keep the money focused on the science and innovation.” He says employees appreciate long-range planning and vision that allows companies to ride out shifting financial trade winds. “There’s something to be said for persistence and never feeling like we are a successful company.” Above all else, employees rank innovations that allow them to make a positive, real impact in the world—not compensation, retirement benefits, or career advancement—as the biggest reward of working in biotech and pharmaceuticals. Blasiak refers to an oft-repeated motto at Novozymes about having a “triple” bottom line. “‘People, planet, profit’—which is totally buzz-wordy—but it really does mean something here,” she says. Because the company’s leaders truly care that profitable products also do some good for people and the environment, Blasiak and her colleagues are inspired to put forward their best effort. “At the end of the day, everyone wants their work to be doing some good.” 14 Questions to Ask Yourself • What do you like to do? What energizes you? • Do you want to do lab work/research? • Where do you want to work? • What do you want to wear to work? • How often do you want to change projects? • • • • • • • What sorts of hours do you want to work? Are you willing to travel? What sort of funding situation do you want to be in? What nonscience interests or skills do you want to use? How important is your income level? Job security? What sort of stress levels do you want to deal with? Would you like to work independently or as part of a team? Questions to Ask in an Informational Interview • • • • • What attracted you to this field? What do you like most or least about this position or field? Describe a typical day or week. What steps did you take to break into this field? What skills are most helpful in your job? How can I develop them? • To what professional associations do you belong? • What advice would you give somebody interested in your line of work? Questions You Might Be Asked at an Interview • Tell me about yourself. • What are your strengths? • What are your weaknesses? • Why this organization? Why this job? • What can you do for us? • Why are you leaving research? (if applicable) Questions to Ask at an Interview • • • • What does the job entail? What are the opportunities for advancement? How will you help with my professional development? What are the future goals for the organization? • What are the roles of different team members? • Tell me about the culture of the organization. Check out the job listings at ScienceCareers.org The AAAS Mass Media Science & Engineering Fellows Program seeks to increase communication skills in student scientists. From grant writing to interacting with their community, these skills will benefit a student’s career path and increase public The Fellowship places advanced undergraduate, graduate, LOCATION and post-graduate science and engineering students at media Various cities across the US sites nationwide to work as science reporters for ten weeks. Past sites have included the Los Angeles Times, WIRED, training in the sciences as they research, write, and report today’s headlines, sharpening their abilities to communicate complex scientific and technical issues to the public. PRIMARY CONTACT DETAILS: AAAS Mass Media Science & Engineering Fellows Program 1200 New York Ave, NW Washington, DC 20005 Email: [email protected] Phone: 202.326.6441 KEY RECRUITING AREAS Communication Agriculture Animal Studies Anthopology Applied Mathematics Astronomy and Planetary Sciences Atmospheric Science Over its 40-year history, the program has supported over About Us Biochemistry 635 fellows. This highly competitive program strengthens the connections between scientists and journalists by placing advanced undergraduate, graduate, and post-graduate level science, engineering and mathematics students at media organizations nationwide for 10 weeks during the summer. Fellows have worked as reporters, editors, researchers, and production assistants at such media outlets as the Los Angeles Times, WIRED, National Public Radio, National Geographic and Scientific American. The AAAS Fellows use their academic training in the sciences as they research, write and report today’s headlines, sharpening their abilities to communicate complex scientific issues to non-specialists. Participants come in knowing the importance of translating their work for the public, but they leave with the tools and the know-how to accomplish this important goal. Over its 40 year history, the program has supported 635 Fellows. Biology (Cell, Molecular, Developmental) Criteria: Nanoscience 1. Applicants must be enrolled as college or university students (graduate, doctoral, or upper level undergraduates) — or within one year of a completed degree — in the physical, biological, geological, health, engineering, computer, or social sciences or mathematics in order to apply. 2. Students enrolled in English, journalism, science journalism, or other non-technical fields are not eligible for these fellowships. 3. Successful applicants must attend an orientation at AAAS headquarters at the beginning of the summer (early June) and a wrap-up session at the end of the summer (mid-August). They will prepare reports on the progress of their fellowships throughout their placement. 17 Neuroscience Write for the Spanish Language Fellow(s) Initiative Los Angeles Times AAAS initiated the Spanish Language Fellowship in 2014 to focus on serving the growing Latino populations of the U.S. by supporting science communication and education in the language of those communities and by addressing issues of importance to the communities. Once again, we are recruiting Spanish Language Fellow(s) who will be able to expand the work with mainstream Spanish news outlets to bring science news to Spanish-speaking communities. Publish in WIRED Work with teams at NPR Join the science desk at National Geographic [email protected] facebook.com/aaasmmfellows 202-326-6441 @AAASMassMedia Chemistry Climate Science Ecology Engineering Environmental Sciences Genetics Geosciences/Earth Sciences History of Science Material Sciences Mathematics Medical Studies Microbiology/Immunology/Virology Nursing Science Oceanography/Marine Sciences Pharmacology/Toxicology Physical Chemistry Physics Physiology Plant Biology/Physiology Statistics A A A S Ma ss Me dia Fellowships understanding of science and technology. National Geographic, and NPR. Fellows use their academic www.aaas.org/mmfellowship www.aaas.org/massmedia EMPLOY ER PROFILE: AAAS Mass Media Science and Engineering Fellows Program November 1. “My time as a AAAS Fellow was among the most valuable of my career.” Enhancing Policy, Transforming Careers LOCATION AS_ScienceCareers_Louis122814.indd 1 Washington, DC KEY RECRUITING AREAS 12/28/14 11:11 AM Doctoral-level degree (PhD, MD, DVM, DSc, etc.) in any of the following: PRIMARY CONTACT DETAILS: Email: [email protected] Social and Behavioral sciences Phone: 202.326.6700 — Kevin Foster, Ph.D., Executive Branch Fellow, National Science Foundation; Executive Director, ICUSP Inc. and Associate Professor, University of Texas at Austin Medical and Health Sciences Biological, physical and earth sciences About Us Enhancing Policy, Transforming Careers AAAS Science & Technology Policy Fellowships (STPF) connects science with policy to foster a network of STEM leaders who understand government and policymaking and are prepared to develop and execute solutions to address societal challenges. make a difference. Transform Your Career. Apply your scientific analysis and technical knowledge to inform policy through assignments in the Legislative, Executive and Judicial Branches. Fellowships Year: September 1, 2017 – August 31, 2018 Details at: aaas.org/stpf/SC Enhancing Policy, Transforming Careers Engineering disciplines (applicants with a Master’s in engineering with 3 years of engineering related professional experience are also eligible to apply) Fellows represent a broad array of discipline backgrounds, US citizenship diversity of career stages and sectors, and a common interest in learning about science policy and willingness to apply their training in new arenas in yearlong assignments in all three branches of the federal government in Washington, D.C. For more than 42 years, scientists and engineers have applied their knowledge and technical expertise to policy-making at the national and international levels. Learn how you can contribute to public service while developing valuable career-enhancing skills and networks! Online Applications Due: November 1, 2016 Stipends from $75,000 to $100,000. Applications due November 1. Computational Sciences and Mathematics 19 A A A S S &T Fellowship i had a monumental experience. you can too. aaas.org/stpf/sc EMPLOY ER PROFILE: AAAS Science & Technology Policy Fellowships EMPLOY ER PROFILE: LOCATION AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 Phone: 1.800.255.5162 About Us AbbVie is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world’s most complex and serious diseases. AbbVie employs approximately 28,000+ people worldwide and markets medicines in more than 170 countries. For further information on the company and its people, portfolio and commitments, please visit www.abbvie.com. KEY RECRUITING AREAS Corporate Research and Development Regulatory Affairs and Compliance Operations Commercial 21 A bbv ie www.abbvie.com/careers EMPLOY ER PROFILE: Caring Deeply. TM Changing Lives. Through cutting-edge science and medicine, Biogen discovers, develops and delivers to patients worldwide innovative therapies for the treatment of serious diseases. Founded in 1978, Biogen is one of the world’s oldest independent biotechnology companies. LOCATION Cambridge, Massachusetts PRIMARY CONTACT DETAILS: 225 Binney Street Cambridge, MA 02142 USA Phone: 781.464.2000 About Us Through cutting-edge science and medicine, Biogen discovers, develops, and delivers to patients worldwide innovative therapies for the treatment of neurodegenerative diseases, hematologic conditions, and autoimmune disorders. Founded in 1978, Biogen is the world’s oldest independent biotechnology company. KEY RECRUITING AREAS Molecular Biology Immunology Fibrosis Neurobiology Pathology Cell Biology Antibody Engineering Computational Biology To learn more about opportunities at Biogen, visit: Postdoctoral Program BIOGEN.COM/CAREERS 23 Biog en biogen.com/careers KEY RECRUITING AREAS Cambridge, MA, USA The scientific questions explored in the department span a wide range and include as diverse topics as Biochemistry and Biophysics, Genetics and Genomics; Development and Cell Biology, Molecular Evolution as well as Neurobiology and Structural Biology. PRIMARY CONTACT DETAILS: Department of Molecular and Cellular Biology Harvard University 52 Oxford Street Cambridge, MA 02138 About Us Greetings and welcome to the Department of Molecular and Cellular Biology (MCB), at the main Cambridge campus of Harvard University. We are seeking highly creative and motivated postdocs with broad interests and outstanding graduate training. At MCB you will find a collaborative and supportive atmosphere and a high level of interaction among students, faculty and postdoctoral fellows. The department is composed of 30-some faculty, 115 graduate students and 150+ postdoctoral fellows from a wide range of places in the Unites States and abroad, giving rise to a distinct international and cosmopolitan flair. A wide range of scientific lectures, conferences and cultural events bring people from disparate fields together on almost a daily basis. Combined with a genuine enthusiasm and a deep-rooted passion for scientific discovery, this spirit makes MCB an exciting place to do research and to explore the many unsolved questions in biology. The department’s development in recent years reflects the revolution occurring in biology that benefits from new genomewide approaches, powerful new computer and microscope tools, and collaborations between biology and other science and engineering disciplines. Please apply directly to relevant MCB Faculty 25 Har v ard Uni ver sit y, Depar t ment of Mole cul ar and Cellul ar Biolog y LOCATION employer prof ile: https://www.mcb.harvard.edu/postdocs EMPLOY ER PROFILE: careers.roche.ch Roche LOCATIONS Basel/Kaiseraugst (Headquarters), Rotkreuz, Schlieren and Reinach in Switzerland, affiliates in more than 150 countries. 8.9 billion Swiss francs in core research and development expenditure in 2014 makes Roche one of the most research focused companies worldwide. Our 120 year heritage and a stable shareholder structure ensure a long-term view and a strong and stable commitment to researching and developing novel treatments in the areas of oncology, immunology, infectious diseases, ophthalmology and neuroscience in order to improve the lives of patients all over the world. Because it’s not just a job. It’s a responsibility. A big one. The next step is yours. careers.roche.ch/research Biochemistry Bioinformatics PRIMARY CONTACT DETAILS: Think beyond. Make a difference. KEY RECRUITING AREAS Biology F. Hoffmann-La Roche Ltd. Grenzacherstrasse 124 CH-4070 Basel Switzerland Biostatistics Biotechnology Chemical Engineering Chemistry Life Sciences About Us Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and neuroscience. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Roche’s personalised healthcare strategy aims at providing medicines and diagnostics that enable tangible improvements in the health, quality of life and survival of patients. Founded in 1896, Roche has been making important contributions to global health for more than a century. Twenty-nine medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and chemotherapy. In 2014, the Roche Group employed 88,500 people worldwide, invested 8.9 billion Swiss francs in R&D and posted sales of 47.5 billion Swiss francs. Genentech, in the United States, is a wholly owned member of the Roche Group. 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